Gene: S100b (S100 protein, beta polypeptide, neural) Mus musculus
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Symbol:
S100b
Name:
S100 protein, beta polypeptide, neural
Description:
Predicted to have several functions, including RAGE receptor binding activity; S100 protein binding activity; and metal ion binding activity. Involved in memory and regulation of neuronal synaptic plasticity. Localizes to the cytoplasm; neuronal cell body; and nucleus. Human ortholog(s) of this gene implicated in Alzheimer's disease; Parkinson's disease; aspergillosis; and schizophrenia. Is expressed in several structures, including alimentary system; integumental system; nervous system; respiratory system; and sensory organ. Orthologous to human S100B (S100 calcium binding protein B); PARTICIPATES IN calcium/calcium-mediated signaling pathway; INTERACTS WITH (S)-nicotine; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type:
protein-coding
RefSeq Status:
VALIDATED
Also known as:
AI850290; Bpb; MGC74317; protein S100-B; S-100 protein beta chain; S-100 protein subunit beta; S100 calcium-binding protein B
Orthologs:
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
S100B (S100 calcium binding protein B) HGNC
EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):
S100b (S100 calcium binding protein B) HGNC
Treefam, EggNOG, NCBI, OMA, HomoloGene, Inparanoid, Panther, PhylomeDB, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):
S100b (S100 calcium binding protein B) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
S100B (S100 calcium binding protein B) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
S100B (S100 calcium binding protein B) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
S100B (S100 calcium binding protein B) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Alliance orthologs 3
Rattus norvegicus (Norway rat):
S100b (S100 calcium binding protein B)
Alliance
DIOPT (Ensembl Compara, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, TreeFam)
Homo sapiens (human):
S100B (S100 calcium binding protein B)
Alliance
DIOPT (Ensembl Compara, HGNC, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, Roundup, TreeFam)
Danio rerio (zebrafish):
s100b (S100 calcium binding protein, beta (neural))
Alliance
DIOPT (Ensembl Compara, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, Roundup, TreeFam)
Latest Assembly:
GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm38 10 76,253,836 - 76,261,319 (+) NCBI GRCm38 GRCm38 mm10 GRCm38 MGSCv37 10 75,716,581 - 75,724,064 (+) NCBI GRCm37 mm9 NCBIm37 MGSCv36 10 75,697,569 - 75,703,813 (+) NCBI mm8 Celera 10 77,297,763 - 77,305,246 (+) NCBI Celera Cytogenetic Map 10 C1 NCBI cM Map 10 38.76 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Disease Annotations
RGD Manual Annotations
Acute Coronary Syndrome ISO RGD:737117 5508825 protein:increased expression:serum RGD Alzheimer's disease IMP 5508775 RGD Alzheimer's disease severity ISO RGD:737117 5508798 ; 5508787 RGD Alzheimer's disease ISO RGD:3615 5508780 protein:decreased expression:cerebrospinal fluid RGD aspergillosis ISO RGD:737117 8695981 DNA:SNP: :427C>T (human) RGD asphyxia neonatorum ISO RGD:737117 5508819 protein:increased expression:urine RGD bacterial meningitis ISO RGD:737117 5508818 protein:increased expression:cerebrospinal fluid RGD bipolar disorder ISO RGD:3615 5508853 protein:increased expression:cerebrospinal fluid RGD borna disease ISO RGD:3615 5508841 protein:decreased expression:cerebellum, cerebral cortex RGD brain disease disease_progression ISO RGD:737117 5508782 RGD brain edema ISO RGD:3615 5508832 associated with Stroke, protein:increased expression:serum RGD Brain Injuries severity ISO RGD:737117 5508761 RGD brain ischemia ISO RGD:3615 5508764 protein:increased expression:serum RGD Cerebral Hemorrhage disease_progression ISO RGD:737117 5508801 RGD Creutzfeldt-Jakob disease ISO RGD:737117 5508781 RGD demyelinating disease ISO RGD:3615 5508823 RGD Dental Pulp Exposure ISO RGD:3615 5508788 protein:increased expression:brain, astrocyte RGD Diabetes Mellitus, Experimental ISO RGD:3615 5508836 protein:altered expression:hippocampus, astrocyte RGD Diabetes Mellitus, Experimental ISO RGD:3615 5508821 protein:increased expression:cerebellum, cerebral cortex, hippocampus RGD dilated cardiomyopathy ISO RGD:737117 2324684 protein:increased expression:serum RGD epilepsy ISO RGD:3615 5508766 protein:increased expression:hippocampus RGD Femoral Fractures ISO RGD:3615 5509053 protein:increased expression:blood RGD Hematoma ISO RGD:3615 5508832 associated with Stroke, protein:increased expression:serum RGD hypertension ISO RGD:737117 5508770 protein:increased expression:serum RGD Hypotension ISO RGD:3615 5508837 protein:increased expression:serum RGD Hypoxia-Ischemia, Brain severity ISO RGD:737117 5508819 associated with Asphyxia Neonatorum, protein:increased expression:urine RGD Inflammation ISO RGD:737117 5508779 associated with Stroke RGD invasive aspergillosis IMP 5508765 RGD Machado-Joseph disease ISO RGD:737117 5508762 protein:increased expression:serum RGD mental depression ISO RGD:3615 5508824 protein:increased expression:hippocampus RGD migraine without aura ISO RGD:737117 5508769 protein:increased expression:serum RGD myocardial infarction ISO RGD:3615 2325647 mRNA, protein:increased expression:left ventricle myocardium, plasma RGD Myocardial Reperfusion Injury ISO RGD:3615 5508825 mRNA, protein:increased expression:myocardium RGD neuromyelitis optica ISO RGD:737117 5508767 RGD Parkinson's disease ISO RGD:737117 5508766 RGD Parkinson's disease IEP 5508763 RGD relapsing-remitting multiple sclerosis ISO RGD:737117 5508822 protein:increased expression:brain, cerebrospinal fluid RGD Reperfusion Injury ISO RGD:3615 5508834 RGD schizophrenia ISO RGD:737117 5508799 protein:increased expression:serum RGD schizophrenia susceptibility ISO RGD:737117 14696780 DNA:SNPs, haplotype:3' utr, cds:5748C>T, 2757C>G (rs9722, rs1051169) (human) RGD Sepsis ISO RGD:737117 5508796 RGD sleep apnea ISO RGD:3615 5508790 protein:increased expression:cerebral cortex, hippocampus, astrocyte RGD Spinal Fractures ISO RGD:737117 5508786 protein:increased expression:serum RGD Stroke severity ISO RGD:3615 5508838 protein:increased expression:serum RGD Stroke severity ISO RGD:737117 5508793 RGD urinary bladder cancer IEP 2316906 mRNA:decreased expression:urinary bladder urothelium RGD visual epilepsy ISO RGD:3615 5509052 protein:increased expression:cerebrospinal fluid RGD West Nile fever ISO RGD:737117 5508797 RGD
Imported Annotations - ClinVar
autistic disorder ISO RGD:737117 8554872 ClinVar Annotator: match by term: Autistic disorder of childhood onset ClinVar PMID:21681106 , PMID:30208311 Axenfeld-Rieger syndrome type 3 ISO RGD:737117 8554872 ClinVar Annotator: match by term: Axenfeld-Rieger syndrome type 3 ClinVar PMID:11170889 , PMID:21681106
Imported Annotations - CTD
Animal Disease Models ISO RGD:737117 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:12888777 Attention Deficit and Disruptive Behavior Disorders ISO RGD:737117 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:25451971 bipolar disorder ISO RGD:737117 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:15581912 , PMID:16476148 brain edema ISO RGD:737117 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:19027832 Brain Injuries ISO RGD:737117 11554173 CTD Direct Evidence: marker/mechanism, therapeutic CTD PMID:11520488 , PMID:21783483 Brain Injuries, Diffuse ISO RGD:737117 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:30076900 Brain Neoplasms ISO RGD:737117 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:27935819 Cerebral Hemorrhage ISO RGD:737117 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:19027832 Down syndrome ISO RGD:737117 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:12888777 Hematoma ISO RGD:737117 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:19027832 intracranial vasospasm ISO RGD:737117 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:12186470 Mercury Poisoning, Nervous System ISO RGD:737117 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:30076900 myocardial infarction ISO RGD:737117 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:9788975
(+)-catechin multiple interactions ISO RGD:737117 6480464 Catechin inhibits the reaction [S100B protein results in increased abundance of Reactive Oxygen Species] more ... CTD PMID:17103373 (+)-pilocarpine increases expression ISO RGD:3615 6480464 Pilocarpine results in increased expression of S100B protein CTD PMID:18226170 (1->3)-beta-D-glucan increases expression ISO RGD:737117 6480464 beta-1, 3-D-glucan results in increased expression of S100B protein CTD PMID:28117141 (R)-lipoic acid multiple interactions ISO RGD:3615 6480464 [Furosemide results in decreased activity of SLC12A2 protein] affects the reaction [Thioctic Acid inhibits the reaction [Ammonia results in increased secretion of S100B protein]], Thioctic Acid inhibits the reaction [Ammonia results in increased secretion of S100B protein] CTD PMID:23880158 (R)-noradrenaline increases expression ISO RGD:737117 6480464 Norepinephrine results in increased expression of S100B mRNA, Norepinephrine results in increased expression of S100B protein CTD PMID:9788975 (R)-noradrenaline affects response to substance ISO RGD:737117 6480464 S100B protein affects the susceptibility to Norepinephrine CTD PMID:9788975 (S)-nicotine decreases expression EXP 6480464 Nicotine results in decreased expression of S100B mRNA CTD PMID:21955143 1,2-dimethylhydrazine decreases expression ISO RGD:3615 6480464 1, 2-Dimethylhydrazine results in decreased expression of S100B mRNA CTD PMID:27840820 1,2-dimethylhydrazine multiple interactions ISO RGD:3615 6480464 [APC protein affects the susceptibility to 1 more ... CTD PMID:27840820 1-chloro-2,4-dinitrobenzene decreases expression ISO RGD:737117 6480464 Dinitrochlorobenzene results in decreased expression of S100B mRNA CTD PMID:17374397 17beta-estradiol increases expression EXP 6480464 Estradiol results in increased expression of S100B mRNA CTD PMID:19484750 2,2,2-tetramine multiple interactions ISO RGD:737117 6480464 Tetradecanoylphorbol Acetate inhibits the reaction [Trientine inhibits the reaction [S100B protein results in increased expression of AGER protein]] more ... CTD PMID:23541064 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:737117 6480464 Tetrachlorodibenzodioxin results in decreased expression of S100B mRNA CTD PMID:17101203 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:3615 6480464 Tetrachlorodibenzodioxin results in increased expression of S100B mRNA CTD PMID:26232522 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of S100B mRNA CTD PMID:24680724 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:3615 6480464 Tetrachlorodibenzodioxin results in decreased expression of S100B mRNA CTD PMID:22808131 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:737117 6480464 Tetrachlorodibenzodioxin results in increased expression of S100B mRNA CTD PMID:21296121 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to S100B promoter] CTD PMID:19654925 3,3',5,5'-tetrabromobisphenol A decreases expression EXP 6480464 tetrabromobisphenol A results in decreased expression of S100B mRNA CTD PMID:25172293 3,4-dihydroxybenzaldehyde multiple interactions ISO RGD:737117 6480464 protocatechualdehyde inhibits the reaction [S100B protein results in increased expression of AGER mRNA] more ... CTD PMID:17597607 3,7-dihydropurine-6-thione increases expression ISO RGD:3615 6480464 Mercaptopurine results in increased expression of S100B mRNA CTD PMID:23358152 3-[3-(tert-butylsulfanyl)-1-(4-chlorobenzyl)-5-(propan-2-yl)-1H-indol-2-yl]-2,2-dimethylpropanoic acid multiple interactions ISO RGD:3615 6480464 MK-886 inhibits the reaction [pirinixic acid affects the expression of S100B protein] CTD PMID:16863991 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO RGD:737117 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of S100B mRNA, [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of S100B mRNA CTD PMID:28628672 4-(ethoxymethylene)-2-phenyloxazol-5-one decreases expression ISO RGD:737117 6480464 Oxazolone results in decreased expression of S100B mRNA CTD PMID:17374397 4-methyl-N1-(3-phenylpropyl)benzene-1,2-diamine multiple interactions ISO RGD:737117 6480464 4-methyl-N1-(3-phenylpropyl)benzene-1 more ... CTD PMID:23541064 6-propyl-2-thiouracil decreases expression ISO RGD:3615 6480464 Propylthiouracil results in decreased expression of S100B mRNA CTD PMID:24780913 aconitine multiple interactions EXP 6480464 ABCB1A gene mutant form promotes the reaction [Aconitine results in increased expression of S100B protein] CTD PMID:28193520 aconitine increases expression EXP 6480464 Aconitine results in increased expression of S100B protein CTD PMID:28193520 aluminium atom increases expression ISO RGD:3615 6480464 Aluminum results in increased expression of S100B protein CTD PMID:16545059 aluminium atom multiple interactions ISO RGD:3615 6480464 Vitamin E inhibits the reaction [Aluminum results in increased expression of S100B protein] CTD PMID:16545059 aluminium(0) increases expression ISO RGD:3615 6480464 Aluminum results in increased expression of S100B protein CTD PMID:16545059 aluminium(0) multiple interactions ISO RGD:3615 6480464 Vitamin E inhibits the reaction [Aluminum results in increased expression of S100B protein] CTD PMID:16545059 aminoguanidine multiple interactions ISO RGD:3615 6480464 pimagedine inhibits the reaction [Streptozocin results in decreased expression of S100B protein], pimagedine inhibits the reaction [Streptozocin results in increased expression of S100B protein] CTD PMID:19494442 ammonia multiple interactions ISO RGD:3615 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Ammonia results in increased secretion of S100B protein] more ... CTD PMID:23284918 , PMID:23880158 ammonia increases secretion ISO RGD:3615 6480464 Ammonia results in increased secretion of S100B protein CTD PMID:23284918 , PMID:23880158 ammonium chloride affects expression ISO RGD:3615 6480464 Ammonium Chloride affects the expression of S100B mRNA CTD PMID:16483693 ammonium chloride decreases expression ISO RGD:3615 6480464 Ammonium Chloride results in decreased expression of S100B protein CTD PMID:16483693 arsenous acid increases expression ISO RGD:737117 6480464 Arsenic Trioxide results in increased expression of S100B mRNA CTD PMID:20458559 astemizole decreases expression ISO RGD:3615 6480464 Astemizole results in decreased expression of S100B mRNA CTD PMID:20221588 bexarotene decreases expression ISO RGD:3615 6480464 bexarotene results in decreased expression of S100B mRNA CTD PMID:16648578 bisphenol A affects expression ISO RGD:3615 6480464 bisphenol A affects the expression of S100B mRNA CTD PMID:25181051 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of S100B mRNA CTD PMID:30245210 bisphenol A multiple interactions ISO RGD:737117 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of S100B mRNA CTD PMID:28628672 bisphenol F multiple interactions ISO RGD:737117 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of S100B mRNA CTD PMID:28628672 buspirone decreases response to substance EXP 6480464 S100B results in decreased susceptibility to Buspirone CTD PMID:12888777 C60 fullerene decreases expression ISO RGD:3615 6480464 fullerene C60 results in decreased expression of S100B mRNA CTD PMID:19167457 cadmium dichloride decreases methylation ISO RGD:3615 6480464 Cadmium Chloride results in decreased methylation of S100B promoter CTD PMID:22457795 calcitriol increases expression ISO RGD:737117 6480464 Calcitriol results in increased expression of S100B mRNA CTD PMID:26485663 capsaicin increases expression ISO RGD:3615 6480464 Capsaicin results in increased expression of S100B protein CTD PMID:17635592 carbofuran increases expression ISO RGD:3615 6480464 Carbofuran results in increased expression of S100B mRNA, Carbofuran results in increased expression of S100B protein CTD PMID:28982980 , PMID:30471306 carbon nanotube decreases expression EXP 6480464 Nanotubes, Carbon results in decreased expression of S100B mRNA CTD PMID:25554681 chrysin multiple interactions EXP 6480464 chrysin inhibits the reaction [Oxidopamine results in increased expression of S100B protein] CTD PMID:29054324 cobalt atom multiple interactions ISO RGD:737117 6480464 [tungsten carbide co-treated with Cobalt] results in decreased expression of S100B mRNA CTD PMID:18078969 cocaine multiple interactions ISO RGD:3615 6480464 ipsapirone inhibits the reaction [Cocaine affects the expression of S100B protein] CTD PMID:8041492 cocaine affects expression ISO RGD:3615 6480464 Cocaine affects the expression of S100B protein CTD PMID:8041492 cycloheximide decreases expression ISO RGD:3615 6480464 Cycloheximide results in decreased expression of S100B mRNA CTD PMID:19146868 dexamethasone multiple interactions ISO RGD:737117 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of S100B mRNA, [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of S100B mRNA CTD PMID:28628672 diarsenic trioxide increases expression ISO RGD:737117 6480464 Arsenic Trioxide results in increased expression of S100B mRNA CTD PMID:20458559 diazinon affects expression ISO RGD:3615 6480464 Diazinon affects the expression of S100B mRNA CTD PMID:22546817 dibenziodolium multiple interactions ISO RGD:737117 6480464 diphenyleneiodonium inhibits the reaction [S100B protein results in increased expression of NOX2 mRNA] CTD PMID:17327432 dibutyl phthalate decreases expression ISO RGD:3615 6480464 Dibutyl Phthalate results in decreased expression of S100B mRNA CTD PMID:21266533 dimethoate increases expression ISO RGD:3615 6480464 Dimethoate results in increased expression of S100B mRNA, Dimethoate results in increased expression of S100B protein CTD PMID:21941777 diuron decreases expression ISO RGD:3615 6480464 Diuron results in decreased expression of S100B mRNA CTD PMID:25152437 dorsomorphin multiple interactions ISO RGD:737117 6480464 [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 endosulfan increases expression ISO RGD:3615 6480464 Endosulfan results in increased expression of S100B mRNA CTD PMID:29391264 entinostat increases expression ISO RGD:737117 6480464 entinostat results in increased expression of S100B mRNA CTD PMID:27188386 ethanol increases expression EXP 6480464 Ethanol results in increased expression of S100B mRNA CTD PMID:21955143 , PMID:30319688 ethanol affects expression EXP 6480464 Ethanol affects the expression of S100B mRNA CTD PMID:30319688 fluoxetine increases response to substance EXP 6480464 S100B protein results in increased susceptibility to Fluoxetine CTD PMID:22113448 fluoxetine increases expression ISO RGD:3615 6480464 Fluoxetine results in increased expression of S100B protein CTD PMID:12960766 fluoxetine increases expression EXP 6480464 Fluoxetine results in increased expression of S100B mRNA, Fluoxetine results in increased expression of S100B protein CTD PMID:12960766 , PMID:20857517 folic acid decreases expression EXP 6480464 Folic Acid results in decreased expression of S100B mRNA CTD PMID:25006883 furosemide multiple interactions ISO RGD:3615 6480464 [Furosemide results in decreased activity of SLC12A2 protein] affects the reaction [Thioctic Acid inhibits the reaction [Ammonia results in increased secretion of S100B protein]], [Furosemide results in decreased activity of SLC12A2 protein] inhibits the reaction [Ammonia results in increased secretion of S100B protein] CTD PMID:23880158 glyphosate affects expression ISO RGD:3615 6480464 glyphosate affects the expression of S100B protein CTD PMID:28627408 heparin affects expression ISO RGD:3615 6480464 Heparin affects the expression of S100B protein CTD PMID:12186470 hydrogen peroxide decreases secretion ISO RGD:3615 6480464 Hydrogen Peroxide results in decreased secretion of S100B protein CTD PMID:18835240 indometacin multiple interactions ISO RGD:737117 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of S100B mRNA, [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of S100B mRNA CTD PMID:28628672 ketamine increases expression ISO RGD:3615 6480464 Ketamine results in increased expression of S100B mRNA CTD PMID:20080153 L-ascorbic acid increases expression ISO RGD:3615 6480464 Ascorbic Acid results in increased expression of S100B mRNA CTD PMID:15372504 lead diacetate increases expression ISO RGD:3615 6480464 lead acetate results in increased expression of S100B protein CTD PMID:17047031 lipoic acid multiple interactions ISO RGD:3615 6480464 [Furosemide results in decreased activity of SLC12A2 protein] affects the reaction [Thioctic Acid inhibits the reaction [Ammonia results in increased secretion of S100B protein]], Thioctic Acid inhibits the reaction [Ammonia results in increased secretion of S100B protein] CTD PMID:23880158 manganese(II) chloride increases expression EXP 6480464 manganese chloride results in increased expression of S100B mRNA, manganese chloride results in increased expression of S100B protein CTD PMID:15295902 mercaptopurine increases expression ISO RGD:3615 6480464 Mercaptopurine results in increased expression of S100B mRNA CTD PMID:23358152 mercury atom increases secretion ISO RGD:737117 6480464 Mercury results in increased secretion of S100B mRNA CTD PMID:30076900 mercury(0) increases secretion ISO RGD:737117 6480464 Mercury results in increased secretion of S100B mRNA CTD PMID:30076900 methylmercury chloride increases expression ISO RGD:3615 6480464 methylmercuric chloride results in increased expression of S100B protein CTD PMID:21783483 monascin multiple interactions ISO RGD:737117 6480464 monascin inhibits the reaction [S100B protein results in decreased expression of GCLM mRNA] more ... CTD PMID:23331247 morphine decreases expression EXP 6480464 Morphine results in decreased expression of S100B mRNA CTD PMID:21955143 N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide multiple interactions ISO RGD:3615 6480464 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Ammonia results in increased secretion of S100B protein] CTD PMID:23284918 nickel sulfate decreases expression ISO RGD:737117 6480464 nickel sulfate results in decreased expression of S100B mRNA CTD PMID:17374397 nicotine decreases expression EXP 6480464 Nicotine results in decreased expression of S100B mRNA CTD PMID:21955143 nitric oxide multiple interactions EXP 6480464 [S100B protein results in increased expression of NOS2 protein] which results in increased abundance of Nitric Oxide CTD PMID:16376947 nitric oxide multiple interactions ISO RGD:3615 6480464 [S100B protein results in increased expression of NOS2 protein] which results in increased abundance of Nitric Oxide CTD PMID:16376947 nitroprusside multiple interactions ISO RGD:3615 6480464 resveratrol inhibits the reaction [Nitroprusside results in increased secretion of S100B protein] CTD PMID:23284918 nitroprusside increases secretion ISO RGD:3615 6480464 Nitroprusside results in increased secretion of S100B protein CTD PMID:23284918 ouabain increases expression ISO RGD:3615 6480464 Ouabain results in increased expression of S100B protein CTD PMID:15581912 oxidopamine increases expression EXP 6480464 Oxidopamine results in increased expression of S100B protein CTD PMID:29054324 oxidopamine multiple interactions EXP 6480464 chrysin inhibits the reaction [Oxidopamine results in increased expression of S100B protein] CTD PMID:29054324 panobinostat multiple interactions ISO RGD:737117 6480464 [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of S100B mRNA CTD PMID:27188386 panobinostat increases expression ISO RGD:737117 6480464 panobinostat results in increased expression of S100B mRNA CTD PMID:26272509 paracetamol decreases expression ISO RGD:737117 6480464 Acetaminophen results in decreased expression of S100B mRNA CTD PMID:26690555 paraquat affects expression ISO RGD:3615 6480464 Paraquat affects the expression of S100B mRNA CTD PMID:16854511 paraquat affects expression ISO RGD:737117 6480464 Paraquat affects the expression of S100B mRNA CTD PMID:29454966 paraquat increases expression ISO RGD:3615 6480464 Paraquat results in increased expression of S100B protein CTD PMID:24521700 paraquat increases expression ISO RGD:737117 6480464 Paraquat results in increased expression of S100B mRNA, Paraquat results in increased expression of S100B protein CTD PMID:25314302 , PMID:30698896 perfluorooctane-1-sulfonic acid increases expression ISO RGD:3615 6480464 perfluorooctane sulfonic acid results in increased expression of S100B protein CTD PMID:20937303 phenethyl caffeate multiple interactions ISO RGD:3615 6480464 NGFR protein affects the susceptibility to [caffeic acid phenethyl ester results in increased expression of S100B protein] CTD PMID:20836997 phenethyl caffeate increases expression ISO RGD:3615 6480464 caffeic acid phenethyl ester results in increased expression of S100B protein CTD PMID:20836997 phenylephrine increases expression ISO RGD:3615 6480464 Phenylephrine results in increased expression of S100B mRNA CTD PMID:15652358 phenylephrine multiple interactions ISO RGD:3615 6480464 S100A6 protein inhibits the reaction [Phenylephrine results in increased expression of S100B mRNA] more ... CTD PMID:15652358 phorbol 13-acetate 12-myristate multiple interactions ISO RGD:737117 6480464 Tetradecanoylphorbol Acetate inhibits the reaction [Trientine inhibits the reaction [S100B protein results in increased expression of AGER protein]], Tetradecanoylphorbol Acetate inhibits the reaction [Trientine inhibits the reaction [S100B protein results in increased expression of BACE1 protein]] CTD PMID:23541064 pirinixic acid multiple interactions ISO RGD:3615 6480464 MK-886 inhibits the reaction [pirinixic acid affects the expression of S100B protein] CTD PMID:16863991 pirinixic acid affects expression ISO RGD:3615 6480464 pirinixic acid affects the expression of S100B protein CTD PMID:16863991 purine-6-thiol increases expression ISO RGD:3615 6480464 Mercaptopurine results in increased expression of S100B mRNA CTD PMID:23358152 quercetin multiple interactions ISO RGD:737117 6480464 Quercetin inhibits the reaction [S100B protein results in increased abundance of Reactive Oxygen Species] more ... CTD PMID:17103373 reactive oxygen species multiple interactions ISO RGD:737117 6480464 Catechin inhibits the reaction [S100B protein results in increased abundance of Reactive Oxygen Species], Quercetin inhibits the reaction [S100B protein results in increased abundance of Reactive Oxygen Species] CTD PMID:17103373 reactive oxygen species increases abundance ISO RGD:3615 6480464 S100B protein results in increased abundance of Reactive Oxygen Species CTD PMID:16376947 reactive oxygen species increases abundance EXP 6480464 S100B protein results in increased abundance of Reactive Oxygen Species CTD PMID:16376947 reactive oxygen species increases abundance ISO RGD:737117 6480464 S100B protein results in increased abundance of Reactive Oxygen Species CTD PMID:17103373 resveratrol increases secretion ISO RGD:3615 6480464 resveratrol results in increased secretion of S100B protein CTD PMID:17554623 resveratrol increases expression ISO RGD:3615 6480464 resveratrol results in increased expression of S100B protein CTD PMID:16904623 resveratrol multiple interactions ISO RGD:3615 6480464 resveratrol inhibits the reaction [Ammonia results in increased secretion of S100B protein], resveratrol inhibits the reaction [Nitroprusside results in increased secretion of S100B protein] CTD PMID:23284918 risperidone increases secretion ISO RGD:3615 6480464 Risperidone results in increased secretion of S100B protein CTD PMID:18421423 SB 203580 multiple interactions EXP 6480464 SB 203580 inhibits the reaction [S100B protein results in increased expression of NOS2 mRNA], SB 203580 inhibits the reaction [S100B protein results in increased expression of NOS2 protein] CTD PMID:16376947 SB 431542 multiple interactions ISO RGD:737117 6480464 [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 Soman decreases expression ISO RGD:3615 6480464 Soman results in decreased expression of S100B mRNA CTD PMID:19281266 streptozocin multiple interactions ISO RGD:3615 6480464 pimagedine inhibits the reaction [Streptozocin results in decreased expression of S100B protein], pimagedine inhibits the reaction [Streptozocin results in increased expression of S100B protein] CTD PMID:19494442 streptozocin decreases expression ISO RGD:3615 6480464 Streptozocin results in decreased expression of S100B protein CTD PMID:19494442 , PMID:20953641 streptozocin increases expression ISO RGD:3615 6480464 Streptozocin results in increased expression of S100B protein CTD PMID:19494442 titanium dioxide decreases expression EXP 6480464 titanium dioxide results in decreased expression of S100B mRNA CTD PMID:23557971 titanium dioxide affects expression EXP 6480464 titanium dioxide affects the expression of S100B mRNA CTD PMID:17656681 trichostatin A increases expression ISO RGD:737117 6480464 trichostatin A results in increased expression of S100B mRNA CTD PMID:24935251 , PMID:26272509 trichostatin A multiple interactions ISO RGD:737117 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of S100B mRNA CTD PMID:27188386 Tungsten carbide multiple interactions ISO RGD:737117 6480464 [tungsten carbide co-treated with Cobalt] results in decreased expression of S100B mRNA CTD PMID:18078969 valproic acid decreases methylation ISO RGD:737117 6480464 Valproic Acid results in decreased methylation of S100B gene CTD PMID:29154799 valproic acid decreases expression EXP 6480464 Valproic Acid results in decreased expression of S100B mRNA CTD PMID:29261810 valproic acid increases expression ISO RGD:737117 6480464 Valproic Acid results in increased expression of S100B mRNA CTD PMID:23179753 more ... valproic acid multiple interactions ISO RGD:737117 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of S100B mRNA CTD PMID:27188386 valproic acid affects expression ISO RGD:737117 6480464 Valproic Acid affects the expression of S100B mRNA CTD PMID:25979313 valproic acid affects expression EXP 6480464 Valproic Acid affects the expression of S100B mRNA CTD PMID:17292431 vinclozolin decreases expression ISO RGD:3615 6480464 vinclozolin results in decreased expression of S100B mRNA CTD PMID:23034163 vitamin E multiple interactions ISO RGD:3615 6480464 Vitamin E inhibits the reaction [Aluminum results in increased expression of S100B protein] CTD PMID:16545059 vorinostat increases expression ISO RGD:737117 6480464 vorinostat results in increased expression of S100B mRNA CTD PMID:27188386 vorinostat multiple interactions ISO RGD:737117 6480464 [NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of S100B mRNA CTD PMID:27188386
Gene-Chemical Interaction Annotations
