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Gene: S100b (S100 protein, beta polypeptide, neural) Mus musculus
Symbol: S100b
Name: S100 protein, beta polypeptide, neural
Description: Predicted to have several functions, including RAGE receptor binding activity; S100 protein binding activity; and metal ion binding activity. Involved in memory and regulation of neuronal synaptic plasticity. Localizes to the cytoplasm; neuronal cell body; and nucleus. Human ortholog(s) of this gene implicated in Alzheimer's disease; Parkinson's disease; aspergillosis; and schizophrenia. Is expressed in several structures, including alimentary system; integumental system; nervous system; respiratory system; and sensory organ. Orthologous to human S100B (S100 calcium binding protein B); PARTICIPATES IN calcium/calcium-mediated signaling pathway; INTERACTS WITH (S)-nicotine; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI850290; Bpb; MGC74317; protein S100-B; S-100 protein beta chain; S-100 protein subunit beta; S100 calcium-binding protein B
Homo sapiens (human) : S100B (S100 calcium binding protein B)  HGNC  Alliance
Rattus norvegicus (Norway rat) : S100b (S100 calcium binding protein B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : S100b (S100 calcium binding protein B)
Pan paniscus (bonobo/pygmy chimpanzee) : S100B (S100 calcium binding protein B)
Canis lupus familiaris (dog) : S100B (S100 calcium binding protein B)
Sus scrofa (pig) : S100B (S100 calcium binding protein B)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm381076,253,836 - 76,261,319 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371075,716,581 - 75,724,064 (+)NCBIGRCm37mm9NCBIm37
MGSCv361075,697,569 - 75,703,813 (+)NCBImm8
Celera1077,297,763 - 77,305,246 (+)NCBICelera
Cytogenetic Map10 C1NCBI
cM Map1038.76NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on S100b
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 11252
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2019-10-29
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.