H3C6 (H3 clustered histone 6) - Rat Genome Database

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Gene: H3C6 (H3 clustered histone 6) Homo sapiens
Analyze
Symbol: H3C6
Name: H3 clustered histone 6
RGD ID: 1351707
HGNC Page HGNC:4769
Description: Enables cadherin binding activity. Involved in epigenetic regulation of gene expression and nucleosome assembly. Acts upstream of with a positive effect on gene expression. Located in nucleoplasm. Part of nucleosome.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: H3 histone family, member D; H3.1; H3/d; H3C1; H3C10; H3C11; H3C12; H3C2; H3C3; H3C4; H3C7; H3C8; H3FD; HIST1H3A; HIST1H3B; HIST1H3C; HIST1H3D; HIST1H3E; HIST1H3F; HIST1H3G; HIST1H3H; HIST1H3I; HIST1H3J; histone 1, H3e; histone cluster 1 H3 family member e; histone cluster 1, H3e; histone H3.1; histone H3/a; histone H3/b; histone H3/c; histone H3/d; histone H3/f; histone H3/h; histone H3/i; histone H3/j; histone H3/k; histone H3/l
RGD Orthologs
Mouse
Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38626,224,178 - 26,227,473 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl626,224,199 - 26,227,473 (+)EnsemblGRCh38hg38GRCh38
GRCh37626,224,406 - 26,227,701 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36626,333,362 - 26,333,823 (+)NCBINCBI36Build 36hg18NCBI36
Build 34626,333,361 - 26,333,823NCBI
Celera627,454,686 - 27,455,147 (+)NCBICelera
Cytogenetic Map6p22.2NCBI
HuRef626,168,383 - 26,168,844 (+)NCBIHuRef
CHM1_1626,227,544 - 26,228,005 (+)NCBICHM1_1
T2T-CHM13v2.0626,092,650 - 26,095,946 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:1916825   PMID:9119399   PMID:9439656   PMID:9566873   PMID:10949293   PMID:10975519   PMID:11080476   PMID:11242053   PMID:11689053   PMID:12408966   PMID:12477932   PMID:12489984  
PMID:12540855   PMID:14657027   PMID:14718166   PMID:14993289   PMID:15010469   PMID:15664198   PMID:16189514   PMID:16246723   PMID:16267050   PMID:16415788   PMID:16415881   PMID:16603238  
PMID:16622419   PMID:16946699   PMID:17052464   PMID:17081972   PMID:17157298   PMID:17353931   PMID:17355966   PMID:17675446   PMID:18292755   PMID:18418070   PMID:19034380   PMID:19135898  
PMID:19410544   PMID:19498464   PMID:19766566   PMID:19797895   PMID:19919681   PMID:19946888   PMID:20080577   PMID:20223770   PMID:20458337   PMID:20498094   PMID:20504901   PMID:20541251  
PMID:20739937   PMID:20871592   PMID:21081503   PMID:21164480   PMID:21167174   PMID:21630459   PMID:21636898   PMID:21685874   PMID:21724829   PMID:21812398   PMID:21873635   PMID:21907836  
PMID:22020285   PMID:22195966   PMID:22623428   PMID:22720776   PMID:23142979   PMID:23275563   PMID:23376485   PMID:23463506   PMID:24311584   PMID:24590075   PMID:24606918   PMID:24699735  
PMID:24788516   PMID:24981860   PMID:25281560   PMID:25416956   PMID:25468996   PMID:25613572   PMID:25615412   PMID:25963833   PMID:26167883   PMID:26527279   PMID:28514442   PMID:29128334  
PMID:29568061   PMID:29760279   PMID:30867594   PMID:31515488   PMID:31759698   PMID:31790919   PMID:32296183   PMID:32814053   PMID:33818074   PMID:33857403   PMID:33961781   PMID:36180920  


Genomics

Comparative Map Data
H3C6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38626,224,178 - 26,227,473 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl626,224,199 - 26,227,473 (+)EnsemblGRCh38hg38GRCh38
GRCh37626,224,406 - 26,227,701 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36626,333,362 - 26,333,823 (+)NCBINCBI36Build 36hg18NCBI36
Build 34626,333,361 - 26,333,823NCBI
Celera627,454,686 - 27,455,147 (+)NCBICelera
Cytogenetic Map6p22.2NCBI
HuRef626,168,383 - 26,168,844 (+)NCBIHuRef
CHM1_1626,227,544 - 26,228,005 (+)NCBICHM1_1
T2T-CHM13v2.0626,092,650 - 26,095,946 (+)NCBIT2T-CHM13v2.0
H3c10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391321,901,798 - 21,902,285 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1321,901,829 - 21,902,239 (+)EnsemblGRCm39 Ensembl
GRCm381321,717,628 - 21,718,115 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1321,717,659 - 21,718,069 (+)EnsemblGRCm38mm10GRCm38
MGSCv371321,809,497 - 21,809,984 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361321,725,093 - 21,725,580 (+)NCBIMGSCv36mm8
Celera1321,993,096 - 21,993,583 (+)NCBICelera
Cytogenetic Map13A3.1NCBI
cM Map137.94NCBI
Hist1h2ail1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81741,996,216 - 41,997,128 (-)NCBIGRCr8
mRatBN7.21741,568,181 - 41,569,093 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1741,568,471 - 41,569,109 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1741,649,350 - 41,649,760 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01743,253,409 - 43,253,819 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01741,527,835 - 41,528,245 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01743,814,773 - 43,815,183 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1743,814,773 - 43,815,183 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01745,671,789 - 45,672,199 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.11748,771,191 - 48,771,314 (-)NCBI
Celera1741,199,476 - 41,199,886 (-)NCBICelera
Cytogenetic Map17p11NCBI

Variants

.
Variants in H3C6
2 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 6p22.3-21.33(chr6:18120520-30767516)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052180]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052180]|See cases [RCV000052180] Chr6:18120520..30767516 [GRCh38]
Chr6:18120751..30735293 [GRCh37]
Chr6:18228730..30843272 [NCBI36]
Chr6:6p22.3-21.33
pathogenic
GRCh38/hg38 6p25.2-21.33(chr6:3224310-30657190)x3 copy number gain See cases [RCV000138956] Chr6:3224310..30657190 [GRCh38]
Chr6:3224544..30624967 [GRCh37]
Chr6:3169543..30732946 [NCBI36]
Chr6:6p25.2-21.33
pathogenic
GRCh38/hg38 6p22.2(chr6:25991402-26280693)x3 copy number gain See cases [RCV000139521] Chr6:25991402..26280693 [GRCh38]
Chr6:25991630..26280921 [GRCh37]
Chr6:26099609..26388900 [NCBI36]
Chr6:6p22.2
likely benign
GRCh38/hg38 6p25.3-12.3(chr6:156974-46789291)x3 copy number gain See cases [RCV000143497] Chr6:156974..46789291 [GRCh38]
Chr6:156974..46757028 [GRCh37]
Chr6:101974..46864987 [NCBI36]
Chr6:6p25.3-12.3
pathogenic
GRCh37/hg19 6p22.2(chr6:26104332-26365573)x4 copy number gain Ductal breast carcinoma [RCV000207323] Chr6:26104332..26365573 [GRCh37]
Chr6:6p22.2
uncertain significance
GRCh37/hg19 6p22.2(chr6:25839165-26536884)x4 copy number gain See cases [RCV000447433] Chr6:25839165..26536884 [GRCh37]
Chr6:6p22.2
uncertain significance
GRCh37/hg19 6p25.3-q27(chr6:156975-170919482)x3 copy number gain See cases [RCV000512067] Chr6:156975..170919482 [GRCh37]
Chr6:6p25.3-q27
pathogenic
GRCh37/hg19 6p25.3-q27(chr6:156975-170919482) copy number gain See cases [RCV000510595] Chr6:156975..170919482 [GRCh37]
Chr6:6p25.3-q27
pathogenic
GRCh37/hg19 6p22.2(chr6:26178542-26670193)x3 copy number gain not provided [RCV000682657] Chr6:26178542..26670193 [GRCh37]
Chr6:6p22.2
uncertain significance
GRCh37/hg19 6p22.2(chr6:25851789-26319486)x3 copy number gain not provided [RCV000682656] Chr6:25851789..26319486 [GRCh37]
Chr6:6p22.2
uncertain significance
GRCh37/hg19 6p25.3-q27(chr6:108666-170980171)x3 copy number gain not provided [RCV000745403] Chr6:108666..170980171 [GRCh37]
Chr6:6p25.3-q27
pathogenic
GRCh37/hg19 6p25.3-q27(chr6:60107-171054786)x3 copy number gain not provided [RCV000745400] Chr6:60107..171054786 [GRCh37]
Chr6:6p25.3-q27
pathogenic
GRCh37/hg19 6p25.3-q27(chr6:165632-170919470)x3 copy number gain not provided [RCV000745404] Chr6:165632..170919470 [GRCh37]
Chr6:6p25.3-q27
pathogenic
GRCh37/hg19 6p22.2(chr6:26110314-26338056)x3 copy number gain not provided [RCV000745546] Chr6:26110314..26338056 [GRCh37]
Chr6:6p22.2
benign
GRCh37/hg19 6p22.2(chr6:26145158-26245236)x3 copy number gain not provided [RCV000745549] Chr6:26145158..26245236 [GRCh37]
Chr6:6p22.2
benign
GRCh37/hg19 6p22.2(chr6:26067580-26306202)x3 copy number gain not provided [RCV000849663] Chr6:26067580..26306202 [GRCh37]
Chr6:6p22.2
uncertain significance
GRCh37/hg19 6p22.2(chr6:25996066-26303969)x3 copy number gain not provided [RCV000847447] Chr6:25996066..26303969 [GRCh37]
Chr6:6p22.2
uncertain significance
GRCh37/hg19 6p22.2(chr6:25896585-26287389)x4 copy number gain not provided [RCV000845790] Chr6:25896585..26287389 [GRCh37]
Chr6:6p22.2
uncertain significance
GRCh37/hg19 6p22.2(chr6:26046566-26670193)x3 copy number gain not provided [RCV001258882] Chr6:26046566..26670193 [GRCh37]
Chr6:6p22.2
uncertain significance
GRCh37/hg19 6p22.2(chr6:26090243-26265667)x3 copy number gain not provided [RCV001258883] Chr6:26090243..26265667 [GRCh37]
Chr6:6p22.2
uncertain significance
GRCh37/hg19 6p22.2(chr6:25839165-26536884) copy number gain not specified [RCV002053562] Chr6:25839165..26536884 [GRCh37]
Chr6:6p22.2
uncertain significance
NM_003532.3(H3C6):c.235T>C (p.Phe79Leu) single nucleotide variant Inborn genetic diseases [RCV003257770] Chr6:26225389 [GRCh38]
Chr6:26225617 [GRCh37]
Chr6:6p22.2
uncertain significance
NM_003532.3(H3C6):c.251G>A (p.Arg84His) single nucleotide variant Inborn genetic diseases [RCV003180986] Chr6:26225405 [GRCh38]
Chr6:26225633 [GRCh37]
Chr6:6p22.2
uncertain significance
NM_003532.3(H3C6):c.116C>T (p.Pro39Leu) single nucleotide variant Inborn genetic diseases [RCV003360479] Chr6:26225270 [GRCh38]
Chr6:26225498 [GRCh37]
Chr6:6p22.2
uncertain significance
NM_003532.3(H3C6):c.199C>T (p.Pro67Ser) single nucleotide variant Inborn genetic diseases [RCV003352318] Chr6:26225353 [GRCh38]
Chr6:26225581 [GRCh37]
Chr6:6p22.2
uncertain significance
NM_003532.3(H3C6):c.14A>C (p.Lys5Thr) single nucleotide variant Inborn genetic diseases [RCV003383696] Chr6:26225168 [GRCh38]
Chr6:26225396 [GRCh37]
Chr6:6p22.2
uncertain significance
NM_003532.3(H3C6):c.244G>A (p.Asp82Asn) single nucleotide variant Inborn genetic diseases [RCV003366374] Chr6:26225398 [GRCh38]
Chr6:26225626 [GRCh37]
Chr6:6p22.2
uncertain significance
Markers in Region
RH92082  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37626,224,486 - 26,224,607UniSTSGRCh37
Build 36626,332,465 - 26,332,586RGDNCBI36
Celera627,453,789 - 27,453,910RGD
Cytogenetic Map6p22.1UniSTS
HuRef626,167,486 - 26,167,607UniSTS
GeneMap99-GB4 RH Map6105.5UniSTS
RH69153  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37626,225,788 - 26,225,946UniSTSGRCh37
Build 36626,333,767 - 26,333,925RGDNCBI36
Celera627,455,091 - 27,455,249RGD
Cytogenetic Map6p22.1UniSTS
HuRef626,168,788 - 26,168,946UniSTS
GeneMap99-GB4 RH Map6105.82UniSTS
NCBI RH Map6324.3UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage
High
Medium 35 550 95 599 30 16 43 1 141 224 28 1
Low 4636 5462 2850 702 2669 439 5841 2971 3508 147 2631 2598 263 1294 4167
Below cutoff 2917 4198 2069 611 2204 315 6360 2696 6547 187 1334 1980 296 2676 3787

Sequence


RefSeq Acc Id: ENST00000614911   ⟹   ENSP00000482271
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl626,225,135 - 26,225,616 (+)Ensembl
RefSeq Acc Id: ENST00000634733   ⟹   ENSP00000489282
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl626,224,199 - 26,227,473 (+)Ensembl
RefSeq Acc Id: NM_001381999   ⟹   NP_001368928
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38626,224,178 - 26,227,473 (+)NCBI
T2T-CHM13v2.0626,092,650 - 26,095,946 (+)NCBI
Sequence:
RefSeq Acc Id: NM_003532   ⟹   NP_003523
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38626,225,135 - 26,225,616 (+)NCBI
GRCh37626,225,383 - 26,225,844 (+)RGD
Build 36626,333,362 - 26,333,823 (+)NCBI Archive
Celera627,454,686 - 27,455,147 (+)RGD
HuRef626,168,383 - 26,168,844 (+)RGD
CHM1_1626,227,544 - 26,228,005 (+)NCBI
T2T-CHM13v2.0626,093,608 - 26,094,089 (+)NCBI
Sequence:
RefSeq Acc Id: NP_003523   ⟸   NM_003532
- UniProtKB: Q71DJ3 (UniProtKB/Swiss-Prot),   Q6NXU4 (UniProtKB/Swiss-Prot),   Q6NWP9 (UniProtKB/Swiss-Prot),   Q6NWP8 (UniProtKB/Swiss-Prot),   Q6ISV8 (UniProtKB/Swiss-Prot),   P16106 (UniProtKB/Swiss-Prot),   P02296 (UniProtKB/Swiss-Prot),   P02295 (UniProtKB/Swiss-Prot),   A5PLR1 (UniProtKB/Swiss-Prot),   A0PJT7 (UniProtKB/Swiss-Prot),   Q93081 (UniProtKB/Swiss-Prot),   P68431 (UniProtKB/Swiss-Prot),   A8K4Y7 (UniProtKB/TrEMBL),   B2R6Y1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001368928   ⟸   NM_001381999
- UniProtKB: Q71DJ3 (UniProtKB/Swiss-Prot),   Q6NXU4 (UniProtKB/Swiss-Prot),   Q6NWP9 (UniProtKB/Swiss-Prot),   Q6NWP8 (UniProtKB/Swiss-Prot),   Q6ISV8 (UniProtKB/Swiss-Prot),   P68431 (UniProtKB/Swiss-Prot),   P16106 (UniProtKB/Swiss-Prot),   P02296 (UniProtKB/Swiss-Prot),   P02295 (UniProtKB/Swiss-Prot),   A5PLR1 (UniProtKB/Swiss-Prot),   A0PJT7 (UniProtKB/Swiss-Prot),   Q93081 (UniProtKB/Swiss-Prot),   A8K4Y7 (UniProtKB/TrEMBL),   B2R6Y1 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSP00000489282   ⟸   ENST00000634733
RefSeq Acc Id: ENSP00000482271   ⟸   ENST00000614911
Protein Domains
Histone H2A/H2B/H3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P68431-F1-model_v2 AlphaFold P68431 1-136 view protein structure

Promoters
RGD ID:6872254
Promoter ID:EPDNEW_H9292
Type:initiation region
Name:HIST1H3E_2
Description:histone cluster 1 H3 family member e
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H9293  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38626,224,178 - 26,224,238EPDNEW
RGD ID:6872256
Promoter ID:EPDNEW_H9293
Type:multiple initiation site
Name:HIST1H3E_1
Description:histone cluster 1 H3 family member e
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H9292  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38626,225,135 - 26,225,195EPDNEW
RGD ID:6804323
Promoter ID:HG_KWN:52586
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell_12Hour,   HeLa_S3,   K562,   Lymphoblastoid
Transcripts:UC003NHB.2
Position:
Human AssemblyChrPosition (strand)Source
Build 36626,332,046 - 26,332,622 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:4769 AgrOrtholog
COSMIC H3C6 COSMIC
Ensembl Genes ENSG00000197153 UniProtKB/Swiss-Prot
  ENSG00000197409 UniProtKB/Swiss-Prot
  ENSG00000273983 UniProtKB/Swiss-Prot
  ENSG00000274750 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSG00000275379 UniProtKB/Swiss-Prot
  ENSG00000275714 UniProtKB/Swiss-Prot
  ENSG00000277775 UniProtKB/Swiss-Prot
  ENSG00000278828 UniProtKB/Swiss-Prot
  ENSG00000286522 UniProtKB/Swiss-Prot
  ENSG00000287080 UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000356476.3 UniProtKB/Swiss-Prot
  ENST00000359303.4 UniProtKB/Swiss-Prot
  ENST00000369163.4 UniProtKB/Swiss-Prot
  ENST00000612966.3 UniProtKB/Swiss-Prot
  ENST00000613854.2 UniProtKB/Swiss-Prot
  ENST00000614378.2 UniProtKB/Swiss-Prot
  ENST00000614911 ENTREZGENE
  ENST00000614911.3 UniProtKB/Swiss-Prot
  ENST00000616365.2 UniProtKB/Swiss-Prot
  ENST00000618052.2 UniProtKB/Swiss-Prot
  ENST00000621411.3 UniProtKB/Swiss-Prot
  ENST00000634733 ENTREZGENE
  ENST00000634733.1 UniProtKB/Swiss-Prot
  ENST00000685041.1 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.20.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000197153 GTEx
  ENSG00000197409 GTEx
  ENSG00000273983 GTEx
  ENSG00000274750 GTEx
  ENSG00000275379 GTEx
  ENSG00000275714 GTEx
  ENSG00000277775 GTEx
  ENSG00000278828 GTEx
  ENSG00000286522 GTEx
  ENSG00000287080 GTEx
HGNC ID HGNC:4769 ENTREZGENE
Human Proteome Map H3C6 Human Proteome Map
InterPro Histone-fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Histone_H2A/H2B/H3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Histone_H3/CENP-A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:8350 UniProtKB/Swiss-Prot
  hsa:8351 UniProtKB/Swiss-Prot
  hsa:8352 UniProtKB/Swiss-Prot
  hsa:8353 UniProtKB/Swiss-Prot
  hsa:8354 UniProtKB/Swiss-Prot
  hsa:8355 UniProtKB/Swiss-Prot
  hsa:8356 UniProtKB/Swiss-Prot
  hsa:8357 UniProtKB/Swiss-Prot
  hsa:8358 UniProtKB/Swiss-Prot
  hsa:8968 UniProtKB/Swiss-Prot
NCBI Gene 8353 ENTREZGENE
OMIM 602813 OMIM
PANTHER HISTONE H3 UniProtKB/TrEMBL
  HISTONE H3.1 UniProtKB/Swiss-Prot
  HISTONE H3.3 UniProtKB/TrEMBL
  PTHR11426 UniProtKB/Swiss-Prot
Pfam Histone UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS HISTONEH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE HISTONE_H3_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HISTONE_H3_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SM00428 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Histone-fold UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
UniProt A0PJT7 ENTREZGENE
  A5PLR1 ENTREZGENE
  A8K4Y7 ENTREZGENE, UniProtKB/TrEMBL
  B2R6Y1 ENTREZGENE, UniProtKB/TrEMBL
  H31_HUMAN UniProtKB/Swiss-Prot
  P02295 ENTREZGENE
  P02296 ENTREZGENE
  P16106 ENTREZGENE
  P68431 ENTREZGENE
  Q6ISV8 ENTREZGENE
  Q6NWP8 ENTREZGENE
  Q6NWP9 ENTREZGENE
  Q6NXU4 ENTREZGENE
  Q71DJ3 ENTREZGENE
  Q93081 ENTREZGENE
UniProt Secondary A0PJT7 UniProtKB/Swiss-Prot
  A5PLR1 UniProtKB/Swiss-Prot
  P02295 UniProtKB/Swiss-Prot
  P02296 UniProtKB/Swiss-Prot
  P16106 UniProtKB/Swiss-Prot
  Q6ISV8 UniProtKB/Swiss-Prot
  Q6NWP8 UniProtKB/Swiss-Prot
  Q6NWP9 UniProtKB/Swiss-Prot
  Q6NXU4 UniProtKB/Swiss-Prot
  Q71DJ3 UniProtKB/Swiss-Prot
  Q93081 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-07-30 H3C6  H3 clustered histone 6  HIST1H3E  histone cluster 1 H3 family member e  Symbol and/or name change 5135510 APPROVED
2016-08-23 HIST1H3E  histone cluster 1 H3 family member e    histone cluster 1, H3e  Symbol and/or name change 5135510 APPROVED