AGER (advanced glycosylation end-product specific receptor) - Rat Genome Database

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Gene: AGER (advanced glycosylation end-product specific receptor) Homo sapiens
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Symbol: AGER
Name: advanced glycosylation end-product specific receptor
RGD ID: 737312
HGNC Page HGNC
Description: Enables several functions, including S100 protein binding activity; amyloid-beta binding activity; and identical protein binding activity. Involved in several processes, including glial cell activation; modulation of chemical synaptic transmission; and positive regulation of intracellular signal transduction. Located in apical plasma membrane; cell junction; and fibrillar center. Implicated in several diseases, including autoimmune disease (multiple); cardiovascular system disease (multiple); cystic fibrosis; kidney failure (multiple); and lupus nephritis. Biomarker of several diseases, including artery disease (multiple); chronic kidney disease (multiple); congestive heart failure (multiple); diabetic retinopathy (multiple); and lung disease (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: advanced glycosylation end product-specific receptor; MGC22357; RAGE; RAGE isoform delta; RAGE isoform NtRAGE-delta; RAGE isoform sRAGE-delta; receptor for advanced glycation end-products; receptor for advanced glycation end-products variant 20; receptor for advanced glycosylation end products; receptor for advanced glycosylation end-products; SCARJ1; sRAGE
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38632,180,969 - 32,184,253 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl632,180,968 - 32,184,322 (-)EnsemblGRCh38hg38GRCh38
GRCh37632,148,746 - 32,152,030 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36632,256,724 - 32,260,001 (-)NCBINCBI36hg18NCBI36
Build 34632,256,723 - 32,260,001NCBI
Celera633,715,793 - 33,719,070 (-)NCBI
Cytogenetic Map6p21.32NCBI
HuRef631,902,943 - 31,906,297 (-)NCBIHuRef
CHM1_1632,151,229 - 32,154,583 (-)NCBICHM1_1
T2T-CHM13v2.0632,034,160 - 32,037,444 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
Acute Coronary Syndrome  (IEP)
acute kidney failure  (IDA)
Acute Lung Injury  (ISO)
adult respiratory distress syndrome  (ISO)
Albuminuria  (IEP,ISO)
Alzheimer's disease  (IEP,ISO)
Aortic Calcification  (ISO)
aortic disease  (ISO,ISS)
aspergillosis  (IAGP)
asthma  (EXP,IEP,ISO)
atherosclerosis  (EXP,IEP,ISO)
atrial fibrillation  (IEP)
bacterial pneumonia  (ISO)
Brain Injuries  (ISO)
brain ischemia  (ISO)
Breast Neoplasms  (IAGP,IEP)
Cardiac Fibrosis  (ISO)
cardiovascular system disease  (IAGP,ISO)
carotid artery disease  (IEP,ISO)
Carotid Artery Injuries  (ISO)
cerebral infarction  (IEP)
chorioamnionitis  (IEP)
Chronic Allograft Dysfunction  (ISO)
chronic kidney disease  (IAGP,IDA,IEP)
chronic obstructive pulmonary disease  (IEP)
clear cell renal cell carcinoma  (IEP)
colorectal carcinoma  (ISS)
congestive heart failure  (IEP)
contact dermatitis  (ISO)
Cor pulmonale  (IEP)
coronary artery disease  (IAGP,IEP)
Coronary Disease  (IEP)
cystic fibrosis  (IAGP,IEP)
diabetes mellitus  (IEP)
diabetic angiopathy  (EXP)
Diabetic Cardiomyopathies  (ISO)
diabetic encephalopathy  (ISO)
Diabetic Foot  (IEP)
Diabetic Nephropathies  (IAGP,IEP,ISO)
diabetic neuropathy  (ISO)
diabetic retinopathy  (IAGP,IEA,IEP,ISO)
end stage renal disease  (IEP)
Epidermal Hyperplasia  (ISO)
Experimental Autoimmune Myocarditis  (ISO)
Experimental Diabetes Mellitus  (ISO)
Fibrosis  (ISO)
Gastrointestinal Diseases  (ISO)
glomerulosclerosis  (ISO)
Hyperalgesia  (EXP,ISO)
hyperglycemia  (EXP)
Hyperoxia  (ISO)
hypertension  (EXP,ISO)
Hypertrophy  (EXP)
impotence  (ISO)
Inflammation  (EXP,IEP)
inflammatory bowel disease  (IEP)
intracranial aneurysm  (ISO)
invasive aspergillosis  (ISO)
invasive ductal carcinoma  (IEP)
Kawasaki disease  (IEP)
kidney disease  (ISO)
Left Ventricular Hypertrophy  (IEP)
leishmaniasis  (ISO)
Lewy body dementia  (EXP)
liver cirrhosis  (IEP)
Liver Reperfusion Injury  (ISO)
Lung Injury  (ISO)
Lung Neoplasms  (IEA)
lung non-small cell carcinoma  (IEP)
lupus nephritis  (IAGP)
melanoma  (IMP)
middle cerebral artery infarction  (EXP,ISO)
morbid obesity  (IDA)
multiple sclerosis  (IAGP)
myocardial infarction  (IAGP,ISO)
Myocardial Ischemia  (IAGP)
Myocardial Reperfusion Injury  (ISO)
Neointima  (IDA)
neovascular inflammatory vitreoretinopathy  (IEP)
Neuralgia  (EXP)
obesity  (IEP,ISO)
occupational asthma  (EXP)
optic nerve disease  (IEP)
osteoarthritis  (EXP,ISO)
osteoporosis  (ISO)
pancreas disease  (EXP)
pancreatic cancer  (IEP)
periodontitis  (IEP,ISO)
Peripheral Nerve Injuries  (EXP)
Peritoneal Fibrosis  (ISO)
polycystic kidney disease  (ISO)
proliferative diabetic retinopathy  (IEP)
prostate cancer  (IEP)
proteinuria  (IAGP)
psoriasis  (IAGP)
pulmonary emphysema  (EXP)
pulmonary fibrosis  (IEP,ISO)
pulmonary hypertension  (IEP)
renal fibrosis  (IEP,ISO)
rheumatoid arthritis  (EXP,IEP)
rosacea  (ISO)
schistosomiasis  (ISO)
schizophrenia  (IAGP)
schizotypal personality disorder  (IAGP)
Sepsis  (ISO)
Skin Neoplasms  (ISO)
Spinal Cord Injuries  (ISO)
Stroke  (IAGP,ISO)
Subarachnoid Hemorrhage  (ISO)
systemic lupus erythematosus  (IAGP)
systemic scleroderma  (IEP,ISO)
Takayasu's arteritis  (IEP)
thromboangiitis obliterans  (ISO)
Tongue Neoplasms  (ISO)
toxic shock syndrome  (ISO)
transient cerebral ischemia  (ISO)
tuberculosis  (ISO)
type 1 diabetes mellitus  (IAGP,IEP,ISO)
type 2 diabetes mellitus  (IAGP,ISO)
uremia  (ISO)
ureteral obstruction  (ISO)
Vascular Calcification  (IEP,ISO)
vascular skin disease  (IAGP)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-Nornicotine  (EXP)
(-)-anisomycin  (EXP)
(-)-epigallocatechin 3-gallate  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP)
2,2,2-tetramine  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4,6-trinitrobenzenesulfonic acid  (ISO)
3,4-dihydroxybenzaldehyde  (EXP,ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-phenylprop-2-enal  (ISO)
acrolein  (ISO)
acrylamide  (EXP)
acteoside  (EXP)
agomelatine  (ISO)
aldehydo-D-glucose  (EXP,ISO)
aldehydo-D-ribose  (ISO)
all-trans-retinol  (ISO)
allyl isothiocyanate  (ISO)
alpha-D-galactose  (ISO)
aminoguanidine  (ISO)
ammonium chloride  (ISO)
ampicillin  (ISO)
anthocyanin  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (EXP,ISO)
aristolochic acid  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
azathioprine  (ISO)
benazepril  (ISO)
benzo[a]pyrene  (EXP)
Bergenin  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (ISO)
Bisphenol A diglycidyl ether  (ISO)
bleomycin A2  (ISO)
butanal  (EXP)
C60 fullerene  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
carnosine  (ISO)
chlorohydrocarbon  (ISO)
cholesterol  (EXP)
cisplatin  (EXP)
curcumin  (ISO)
D-glucose  (EXP,ISO)
D-ribofuranose  (ISO)
dapagliflozin  (ISO)
dichlorine  (ISO)
diclofenac  (EXP,ISO)
dicloxacillin  (ISO)
dioxygen  (ISO)
disodium selenite  (ISO)
estriol  (EXP)
ethanol  (ISO)
Ethyl pyruvate  (ISO)
febuxostat  (ISO)
flutamide  (EXP,ISO)
fructose  (ISO)
fulvestrant  (EXP)
furan  (ISO)
galactose  (ISO)
gallic acid  (ISO)
genistein  (ISO)
gentamycin  (ISO)
geraniol  (ISO)
glucose  (EXP,ISO)
graphene oxide  (ISO)
hesperetin  (ISO)
Honokiol  (ISO)
hydrogen peroxide  (ISO)
leflunomide  (ISO)
linoleic acid  (ISO)
lipopolysaccharide  (EXP,ISO)
losartan  (ISO)
luteolin  (EXP)
LY294002  (ISO)
lycopene  (EXP)
mangiferin  (ISO)
mebendazole  (EXP)
melatonin  (ISO)
mesalamine  (ISO)
metformin  (ISO)
methylglyoxal  (EXP,ISO)
methylmercury chloride  (ISO)
naphthalene  (ISO)
nitrofen  (ISO)
oleanolic acid  (EXP)
oxidopamine  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
pentanal  (EXP)
pentetrazol  (ISO)
permethrin  (ISO)
phorbol 13-acetate 12-myristate  (EXP)
pioglitazone  (ISO)
potassium dichromate  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
procyanidin B2  (ISO)
procyanidin B3  (ISO)
propanal  (EXP)
protein kinase inhibitor  (ISO)
Pyridostigmine bromide  (ISO)
quercetin  (EXP)
reactive oxygen species  (ISO)
resveratrol  (EXP)
rotenone  (EXP)
rutin  (EXP)
SB 203580  (ISO)
silver atom  (EXP)
silver(0)  (EXP)
simvastatin  (EXP)
sodium arsenite  (EXP,ISO)
sodium fluoride  (ISO)
streptozocin  (ISO)
testosterone  (EXP)
thioacetamide  (ISO)
titanium dioxide  (ISO)
toluene 2,4-diisocyanate  (EXP,ISO)
trichloroethene  (ISO)
triptonide  (ISO)
tris(2-butoxyethyl) phosphate  (EXP)
vinclozolin  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
astrocyte activation  (IGI)
astrocyte development  (IEA,ISO)
brain development  (ISO)
calcium ion homeostasis  (ISO)
cell surface receptor signaling pathway  (TAS)
cellular response to amyloid-beta  (IEA,ISS)
cellular response to fatty acid  (ISO)
cellular response to glucose stimulus  (ISO)
cellular response to hydrogen peroxide  (ISO)
cellular response to organic cyclic compound  (ISO)
cellular response to xenobiotic stimulus  (ISO)
endocytosis  (IEA)
glucose mediated signaling pathway  (IDA)
glycoprotein metabolic process  (ISO)
induction of positive chemotaxis  (IEA,ISO)
inflammatory response  (IEA,ISO,TAS)
learning or memory  (IGI)
lung development  (ISO)
microglial cell activation  (IEA,IGI,ISS)
negative regulation of advanced glycation end-product receptor activity  (ISO)
negative regulation of blood circulation  (IEA,ISS)
negative regulation of cell adhesion  (ISO)
negative regulation of collagen biosynthetic process  (ISO)
negative regulation of connective tissue replacement involved in inflammatory response wound healing  (ISO)
negative regulation of endothelial cell migration  (ISO)
negative regulation of endothelial cell proliferation  (ISO)
negative regulation of interleukin-10 production  (IDA)
negative regulation of long-term synaptic depression  (IGI)
negative regulation of long-term synaptic potentiation  (IEA,IGI,ISS)
negative regulation of osteoblast proliferation  (ISO)
negative regulation of protein phosphorylation  (ISO)
neuron projection development  (IGI,ISO)
obsolete modulation of age-related behavioral decline  (IGI)
positive regulation of activated T cell proliferation  (IMP)
positive regulation of apoptotic process  (ISO)
positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process  (IGI)
positive regulation of autophagy  (ISO)
positive regulation of cell migration  (ISO)
positive regulation of chemokine production  (IEA,ISS)
positive regulation of dendritic cell differentiation  (IMP)
positive regulation of endothelial cell apoptotic process  (ISO)
positive regulation of endothelin production  (IEA,ISS)
positive regulation of epithelial to mesenchymal transition  (ISO)
positive regulation of ERK1 and ERK2 cascade  (IGI)
positive regulation of fibroblast migration  (ISO)
positive regulation of fibroblast proliferation  (ISO)
positive regulation of gene expression  (ISO)
positive regulation of heterotypic cell-cell adhesion  (IGI)
positive regulation of inflammatory response  (ISO)
positive regulation of interleukin-1 beta production  (IEA,ISS)
positive regulation of interleukin-12 production  (IMP)
positive regulation of interleukin-6 production  (IEA,ISS)
positive regulation of JNK cascade  (IGI)
positive regulation of JUN kinase activity  (IEA,ISO)
positive regulation of monocyte chemotactic protein-1 production  (IEA,ISO)
positive regulation of monocyte extravasation  (IMP)
positive regulation of neuron apoptotic process  (ISO)
positive regulation of neuron death  (ISO)
positive regulation of NF-kappaB transcription factor activity  (IDA,IGI)
positive regulation of NIK/NF-kappaB signaling  (IGI)
positive regulation of p38MAPK cascade  (IGI)
positive regulation of phagocytosis, engulfment  (ISO)
positive regulation of potassium ion transmembrane transporter activity  (ISO)
positive regulation of protein phosphorylation  (IGI,ISO)
positive regulation of reactive oxygen species metabolic process  (ISO)
positive regulation of smooth muscle cell migration  (ISO)
positive regulation of smooth muscle cell proliferation  (ISO)
positive regulation of tumor necrosis factor production  (IEA,ISS)
positive regulation of type B pancreatic cell apoptotic process  (ISO)
protein localization to membrane  (IEA,ISO)
receptor signaling pathway via JAK-STAT  (ISO)
regulation of CD4-positive, alpha-beta T cell activation  (IDA)
regulation of DNA binding  (IEA,ISO)
regulation of inflammatory response  (IBA,IEA)
regulation of long-term synaptic potentiation  (IEA,ISS)
regulation of NIK/NF-kappaB signaling  (NAS)
regulation of p38MAPK cascade  (IBA,IEA,ISS)
regulation of spontaneous synaptic transmission  (IGI)
regulation of synaptic plasticity  (TAS)
regulation of T cell mediated cytotoxicity  (IDA)
response to activity  (ISO)
response to amyloid-beta  (IEA,ISS,TAS)
response to fructose  (ISO)
response to genistein  (ISO)
response to hyperoxia  (ISO)
response to hypoxia  (IEA,ISO)
response to methylglyoxal  (ISO)
response to selenite ion  (ISO)
response to vitamin A  (ISO)
response to wounding  (TAS)
transcytosis  (IEA,ISS)
transdifferentiation  (ISO)
transport across blood-brain barrier  (IDA,NAS)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
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PMID:24284407   PMID:24302816   PMID:24303504   PMID:24303922   PMID:24304868   PMID:24329736   PMID:24363518   PMID:24373844   PMID:24395344   PMID:24397807   PMID:24418399   PMID:24420130  
PMID:24427342   PMID:24441189   PMID:24472555   PMID:24474694   PMID:24484607   PMID:24486339   PMID:24510323   PMID:24515114   PMID:24520905   PMID:24526523   PMID:24535058   PMID:24554430  
PMID:24564838   PMID:24603633   PMID:24605038   PMID:24613454   PMID:24625976   PMID:24656601   PMID:24697697   PMID:24705787   PMID:24727234   PMID:24740401   PMID:24742661   PMID:24744309  
PMID:24776932   PMID:24824951   PMID:24839222   PMID:24870978   PMID:24887223   PMID:24934531   PMID:24952599   PMID:24971542   PMID:24978055   PMID:24982031   PMID:24984291   PMID:25002577  
PMID:25012910   PMID:25014735   PMID:25016700   PMID:25031745   PMID:25039001   PMID:25043528   PMID:25044082   PMID:25114379   PMID:25123133   PMID:25136083   PMID:25147225   PMID:25223881  
PMID:25231638   PMID:25310905   PMID:25330185   PMID:25341034   PMID:25355250   PMID:25385222   PMID:25407489   PMID:25428166   PMID:25467215   PMID:25470016   PMID:25490770   PMID:25495026  
PMID:25499973   PMID:25503556   PMID:25509346   PMID:25531888   PMID:25562186   PMID:25572180   PMID:25572331   PMID:25582438   PMID:25593504   PMID:25603950   PMID:25607269   PMID:25652880  
PMID:25671828   PMID:25681682   PMID:25684181   PMID:25689357   PMID:25707513   PMID:25724694   PMID:25744544   PMID:25744702   PMID:25751601   PMID:25751734   PMID:25754382   PMID:25772690  
PMID:25786107   PMID:25789318   PMID:25802195   PMID:25811984   PMID:25825217   PMID:25832424   PMID:25854354   PMID:25877715   PMID:25910212   PMID:25932660   PMID:25956266   PMID:25966147  
PMID:25974999   PMID:25988707   PMID:25994997   PMID:26005850   PMID:26011179   PMID:26011358   PMID:26018980   PMID:26045736   PMID:26048613   PMID:26052716   PMID:26078977   PMID:26083729  
PMID:26114112   PMID:26125438   PMID:26142969   PMID:26186194   PMID:26193421   PMID:26202300   PMID:26211596   PMID:26216409   PMID:26224839   PMID:26226616   PMID:26253613   PMID:26261503  
PMID:26274928   PMID:26303759   PMID:26313784   PMID:26316588   PMID:26325204   PMID:26349055   PMID:26382057   PMID:26391982   PMID:26392152   PMID:26408307   PMID:26429324   PMID:26436377  
PMID:26440051   PMID:26456846   PMID:26472922   PMID:26491690   PMID:26497299   PMID:26502815   PMID:26545872   PMID:26566598   PMID:26569122   PMID:26586913   PMID:26590417   PMID:26607824  
PMID:26657980   PMID:26664786   PMID:26682535   PMID:26745632   PMID:26758977   PMID:26770981   PMID:26782423   PMID:26782577   PMID:26788516   PMID:26801062   PMID:26820600   PMID:26825459  
PMID:26828298   PMID:26857858   PMID:26871627   PMID:26873694   PMID:26878774   PMID:26880860   PMID:26885882   PMID:26895319   PMID:26905625   PMID:26928771   PMID:26930711   PMID:26991258  
PMID:27015414   PMID:27022018   PMID:27026438   PMID:27033231   PMID:27172264   PMID:27188863   PMID:27229106   PMID:27241711   PMID:27263094   PMID:27270765   PMID:27270766   PMID:27277623  
PMID:27279795   PMID:27297108   PMID:27297874   PMID:27300745   PMID:27320800   PMID:27323159   PMID:27323891   PMID:27372036   PMID:27421025   PMID:27434276   PMID:27434539   PMID:27448675  
PMID:27449608   PMID:27476953   PMID:27488419   PMID:27524199   PMID:27524699   PMID:27556030   PMID:27563375   PMID:27598566   PMID:27641663   PMID:27655844   PMID:27669433   PMID:27684793  
PMID:27699858   PMID:27710974   PMID:27714575   PMID:27755550   PMID:27792788   PMID:27798148   PMID:27804051   PMID:27814276   PMID:27816054   PMID:27818100   PMID:27829696   PMID:27830944  
PMID:27873077   PMID:27883367   PMID:27890722   PMID:27930580   PMID:27965400   PMID:27967251   PMID:28013188   PMID:28017722   PMID:28042203   PMID:28045617   PMID:28078875   PMID:28092162  
PMID:28108276   PMID:28116308   PMID:28125989   PMID:28163201   PMID:28186988   PMID:28187002   PMID:28198072   PMID:28223295   PMID:28224704   PMID:28226412   PMID:28248552   PMID:28251435  
PMID:28285361   PMID:28373983   PMID:28397051   PMID:28399536   PMID:28403886   PMID:28428279   PMID:28433998   PMID:28474638   PMID:28535664   PMID:28558055   PMID:28630869   PMID:28631505  
PMID:28660308   PMID:28695773   PMID:28760504   PMID:28811295   PMID:28825156   PMID:28834384   PMID:28849117   PMID:28864204   PMID:28867179   PMID:28956473   PMID:28974473   PMID:29040721  
PMID:29068471   PMID:29104727   PMID:29156655   PMID:29193068   PMID:29222432   PMID:29257350   PMID:29258824   PMID:29271076   PMID:29283384   PMID:29298878   PMID:29317590   PMID:29337308  
PMID:29385725   PMID:29386700   PMID:29394248   PMID:29421442   PMID:29444082   PMID:29445087   PMID:29449307   PMID:29451661   PMID:29518356   PMID:29573228   PMID:29620238   PMID:29670673  
PMID:29673663   PMID:29702093   PMID:29752466   PMID:29774570   PMID:29804482   PMID:29845254   PMID:29846968   PMID:29850572   PMID:29928018   PMID:29963680   PMID:30021884   PMID:30030153  
PMID:30085099   PMID:30130135   PMID:30137355   PMID:30139236   PMID:30180189   PMID:30246940   PMID:30258050   PMID:30280653   PMID:30297199   PMID:30334817   PMID:30401627   PMID:30402462  
PMID:30409203   PMID:30424768   PMID:30456802   PMID:30482197   PMID:30497069   PMID:30554489   PMID:30556321   PMID:30568439   PMID:30585773   PMID:30755202   PMID:30778553   PMID:30781346  
PMID:30806068   PMID:30824390   PMID:30838867   PMID:30870511   PMID:30903794   PMID:30971245   PMID:31071146   PMID:31078654   PMID:31082855   PMID:31141790   PMID:31160611   PMID:31175506  
PMID:31189290   PMID:31248316   PMID:31250032   PMID:31297698   PMID:31502571   PMID:31534114   PMID:31562296   PMID:31611559   PMID:31677348   PMID:31779212   PMID:31818258   PMID:31844158  
PMID:31870801   PMID:31912881   PMID:31937554   PMID:32017530   PMID:32066471   PMID:32076951   PMID:32114455   PMID:32124957   PMID:32132041   PMID:32191386   PMID:32296183   PMID:32304694  
PMID:32367292   PMID:32370733   PMID:32382012   PMID:32460581   PMID:32468030   PMID:32470565   PMID:32482028   PMID:32544495   PMID:32544923   PMID:32552251   PMID:32657776   PMID:32665403  
PMID:32666702   PMID:32676989   PMID:32732977   PMID:32783323   PMID:32799375   PMID:32800556   PMID:32814053   PMID:32819586   PMID:32936764   PMID:32958253   PMID:32973746   PMID:32986722  
PMID:33019603   PMID:33030958   PMID:33086527   PMID:33109194   PMID:33119615   PMID:33123906   PMID:33126315   PMID:33161078   PMID:33186591   PMID:33187505   PMID:33207863   PMID:33284049  
PMID:33325305   PMID:33399986   PMID:33436632   PMID:33455114   PMID:33570767   PMID:33571540   PMID:33607399   PMID:33629304   PMID:33707701   PMID:33840670   PMID:33896376   PMID:33918759  
PMID:33922995   PMID:34072468   PMID:34125766   PMID:34130712   PMID:34156100   PMID:34182498   PMID:34204735   PMID:34214138   PMID:34237330   PMID:34247378   PMID:34338585   PMID:34360919  
PMID:34369271   PMID:34400366   PMID:34445297   PMID:34473880   PMID:34477479   PMID:34572568   PMID:34653793   PMID:34708514   PMID:34745088   PMID:34769147   PMID:34806241   PMID:34816916  
PMID:34863459   PMID:34944030   PMID:35064413   PMID:35110523   PMID:35144588   PMID:35269546   PMID:35343275   PMID:35461309  


Genomics

Comparative Map Data
AGER
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38632,180,969 - 32,184,253 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl632,180,968 - 32,184,322 (-)EnsemblGRCh38hg38GRCh38
GRCh37632,148,746 - 32,152,030 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36632,256,724 - 32,260,001 (-)NCBINCBI36hg18NCBI36
Build 34632,256,723 - 32,260,001NCBI
Celera633,715,793 - 33,719,070 (-)NCBI
Cytogenetic Map6p21.32NCBI
HuRef631,902,943 - 31,906,297 (-)NCBIHuRef
CHM1_1632,151,229 - 32,154,583 (-)NCBICHM1_1
T2T-CHM13v2.0632,034,160 - 32,037,444 (-)NCBI
Ager
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391734,816,545 - 34,819,911 (+)NCBIGRCm39mm39
GRCm39 Ensembl1734,816,836 - 34,819,910 (+)Ensembl
GRCm381734,597,460 - 34,600,937 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1734,597,862 - 34,600,936 (+)EnsemblGRCm38mm10GRCm38
MGSCv371734,734,807 - 34,737,877 (+)NCBIGRCm37mm9NCBIm37
MGSCv361734,205,945 - 34,208,989 (+)NCBImm8
Celera1737,693,022 - 37,696,092 (+)NCBICelera
Cytogenetic Map17B1NCBI
Ager
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2204,148,150 - 4,151,361 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl204,147,890 - 4,151,078 (-)Ensembl
Rnor_6.0204,363,152 - 4,366,079 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl204,363,152 - 4,366,079 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0206,442,508 - 6,445,435 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4204,250,613 - 4,253,540 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1204,250,839 - 4,253,767 (-)NCBI
Celera203,879,126 - 3,882,053 (+)NCBICelera
Cytogenetic Map20p12NCBI
Ager
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955437645,897 - 648,479 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955437645,482 - 648,607 (-)NCBIChiLan1.0ChiLan1.0
AGER
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1632,708,251 - 32,711,641 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl632,708,251 - 32,711,641 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0631,828,363 - 31,831,981 (-)NCBIMhudiblu_PPA_v0panPan3
AGER
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1121,574,251 - 1,577,410 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl121,574,251 - 1,577,129 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha121,707,946 - 1,710,824 (-)NCBI
ROS_Cfam_1.0121,712,483 - 1,715,623 (-)NCBI
ROS_Cfam_1.0 Ensembl121,712,483 - 1,715,351 (-)Ensembl
UMICH_Zoey_3.1121,575,515 - 1,578,386 (-)NCBI
UNSW_CanFamBas_1.0121,641,097 - 1,643,974 (-)NCBI
UU_Cfam_GSD_1.0121,707,421 - 1,710,298 (-)NCBI
Ager
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494636,139,331 - 36,142,908 (-)NCBI
SpeTri2.0NW_0049367271,418,342 - 1,422,005 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AGER
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl724,218,116 - 24,228,756 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1724,218,116 - 24,221,162 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2728,038,957 - 28,042,327 (-)NCBISscrofa10.2Sscrofa10.2susScr3
AGER
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11739,847,343 - 39,851,288 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl1739,847,759 - 39,851,127 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604432,080,456 - 32,084,078 (-)NCBIVero_WHO_p1.0
Ager
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475424,138,086 - 24,140,900 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
RH40485  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37838,457,853 - 38,457,999UniSTSGRCh37
GRCh37632,148,283 - 32,148,429UniSTSGRCh37
Build 36632,256,261 - 32,256,407RGDNCBI36
Celera837,411,195 - 37,411,341UniSTS
Celera633,715,330 - 33,715,476RGD
Cytogenetic Map8p11.22UniSTS
Cytogenetic Map6p21.3UniSTS
HuRef836,993,139 - 36,993,285UniSTS
HuRef631,902,481 - 31,902,627UniSTS
RH65115  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37838,457,740 - 38,457,970UniSTSGRCh37
GRCh37632,148,312 - 32,148,542UniSTSGRCh37
Build 36632,256,290 - 32,256,520RGDNCBI36
Celera837,411,082 - 37,411,312UniSTS
Celera633,715,359 - 33,715,589RGD
Cytogenetic Map8p11.22UniSTS
Cytogenetic Map6p21.3UniSTS
HuRef836,993,026 - 36,993,256UniSTS
HuRef631,902,510 - 31,902,740UniSTS
RH67947  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37838,457,785 - 38,457,875UniSTSGRCh37
GRCh37632,148,407 - 32,148,497UniSTSGRCh37
Build 36632,256,385 - 32,256,475RGDNCBI36
Celera837,411,127 - 37,411,217UniSTS
Celera633,715,454 - 33,715,544RGD
Cytogenetic Map8p11.22UniSTS
Cytogenetic Map6p21.3UniSTS
HuRef836,993,071 - 36,993,161UniSTS
HuRef631,902,605 - 31,902,695UniSTS
RH46823  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37632,153,445 - 32,153,615UniSTSGRCh37
GRCh373142,897,006 - 142,897,184UniSTSGRCh37
Build 363144,379,696 - 144,379,874RGDNCBI36
Celera633,720,489 - 33,720,659UniSTS
Celera3141,320,402 - 141,320,579RGD
Cytogenetic Map3q24UniSTS
Cytogenetic Map6p21.3UniSTS
HuRef631,907,640 - 31,907,810UniSTS
HuRef3140,269,283 - 140,269,459UniSTS
GDB:607721  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37632,153,249 - 32,154,023UniSTSGRCh37
GRCh373142,896,599 - 142,897,372UniSTSGRCh37
Build 363144,379,289 - 144,380,062RGDNCBI36
Celera633,720,296 - 33,721,067UniSTS
Celera3141,319,995 - 141,320,768RGD
Cytogenetic Map3q24UniSTS
Cytogenetic Map6p21.3UniSTS
HuRef631,907,447 - 31,908,218UniSTS
HuRef3140,268,876 - 140,269,648UniSTS
PMC162222P2  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37632,150,442 - 32,151,423UniSTSGRCh37
Build 36632,258,420 - 32,259,401RGDNCBI36
Celera633,717,489 - 33,718,470RGD
Cytogenetic Map6p21.3UniSTS
HuRef631,904,640 - 31,905,621UniSTS
PMC203021P1  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37632,150,444 - 32,150,915UniSTSGRCh37
Build 36632,258,422 - 32,258,893RGDNCBI36
Celera633,717,491 - 33,717,962RGD
Cytogenetic Map6p21.3UniSTS
HuRef631,904,642 - 31,905,113UniSTS
D3S4540  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37632,153,242 - 32,153,518UniSTSGRCh37
GRCh373142,897,103 - 142,897,379UniSTSGRCh37
Build 363144,379,793 - 144,380,069RGDNCBI36
Celera633,720,289 - 33,720,562UniSTS
Celera3141,320,499 - 141,320,775RGD
Cytogenetic Map3q24UniSTS
Cytogenetic Map6p21.3UniSTS
HuRef631,907,440 - 31,907,713UniSTS
HuRef3140,269,380 - 140,269,655UniSTS
D6S1871  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37632,148,745 - 32,148,919UniSTSGRCh37
Build 36632,256,723 - 32,256,897RGDNCBI36
Celera633,715,792 - 33,715,966RGD
Cytogenetic Map6p21.3UniSTS
HuRef631,902,943 - 31,903,117UniSTS
Stanford-G3 RH Map61672.0UniSTS
GeneMap99-GB4 RH Map6145.45UniSTS
GeneMap99-GB4 RH Map6120.03UniSTS
Whitehead-RH Map6179.7UniSTS
NCBI RH Map6509.1UniSTS
GeneMap99-G3 RH Map61804.0UniSTS
STS-D60277  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37838,457,758 - 38,457,875UniSTSGRCh37
GRCh37632,148,407 - 32,148,524UniSTSGRCh37
Build 36632,256,385 - 32,256,502RGDNCBI36
Celera633,715,454 - 33,715,571RGD
Celera837,411,100 - 37,411,217UniSTS
Cytogenetic Map6p21.3UniSTS
Cytogenetic Map8p11.22UniSTS
HuRef836,993,044 - 36,993,161UniSTS
HuRef631,902,605 - 31,902,722UniSTS
GeneMap99-GB4 RH Map6120.03UniSTS
NCBI RH Map6509.1UniSTS
MARC_10431-10432:999637141:1  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37632,151,138 - 32,151,505UniSTSGRCh37
Build 36632,259,116 - 32,259,483RGDNCBI36
Celera633,718,185 - 33,718,552RGD
HuRef631,905,336 - 31,905,703UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:3725
Count of miRNA genes:702
Interacting mature miRNAs:850
Transcripts:ENST00000375055, ENST00000375056, ENST00000375065, ENST00000375067, ENST00000375069, ENST00000375070, ENST00000375076, ENST00000438221, ENST00000450110, ENST00000469940, ENST00000473619, ENST00000484849, ENST00000488669, ENST00000538695
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High 314
Medium 1503 1222 1104 92 1543 53 1779 728 1451 126 1142 1089 43 511 1106 1
Low 929 1762 611 522 405 403 2576 1465 2249 286 305 206 127 693 1682 3
Below cutoff 8 8 8 9 6 2 1 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_029868 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001136 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001206929 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001206932 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001206934 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001206936 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001206940 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001206954 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001206966 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_172197 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_038190 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017010328 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047418260 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047418261 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001743189 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001743190 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB036432 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB061668 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB061669 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF001095 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF065211 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF065212 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF208289 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF502127 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF536236 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF536237 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF537303 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ012753 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ133822 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ238896 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK298100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK313178 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL662830 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL662884 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL845464 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY755619 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY755620 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY755621 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY755622 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY755623 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY755624 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY755625 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY755626 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY755627 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY755628 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC020669 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM971899 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX284686 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX927239 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471081 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068272 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR812478 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR933878 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CS300822 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D28769 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ104251 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ104252 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ104253 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ104254 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU117141 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU428811 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU428812 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU428813 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU428814 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU428815 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU428816 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU826616 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU826617 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU826618 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU826619 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU826620 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ545655 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU139370 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU139371 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU139372 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU139373 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU139374 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU139375 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU139376 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU139377 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU139378 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU139379 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU139380 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU139381 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU139382 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU139383 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU139384 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ148133 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ148134 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ148135 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KC692917 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KY500144 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KY500145 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KY500146 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KY500147 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KY500148 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M91211 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U89336 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y18060 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y18061 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000375055   ⟹   ENSP00000364195
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl632,180,968 - 32,184,246 (-)Ensembl
RefSeq Acc Id: ENST00000375056   ⟹   ENSP00000364196
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl632,182,880 - 32,184,237 (-)Ensembl
RefSeq Acc Id: ENST00000375065   ⟹   ENSP00000364206
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl632,181,143 - 32,184,222 (-)Ensembl
RefSeq Acc Id: ENST00000375067   ⟹   ENSP00000364208
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl632,180,968 - 32,184,237 (-)Ensembl
RefSeq Acc Id: ENST00000375069   ⟹   ENSP00000364210
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl632,180,968 - 32,184,322 (-)Ensembl
RefSeq Acc Id: ENST00000375070   ⟹   ENSP00000364211
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl632,180,968 - 32,184,322 (-)Ensembl
RefSeq Acc Id: ENST00000375076   ⟹   ENSP00000364217
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl632,180,969 - 32,184,253 (-)Ensembl
RefSeq Acc Id: ENST00000438221   ⟹   ENSP00000387887
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl632,180,968 - 32,184,322 (-)Ensembl
RefSeq Acc Id: ENST00000450110   ⟹   ENSP00000398466
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl632,182,868 - 32,184,235 (-)Ensembl
RefSeq Acc Id: ENST00000469940
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl632,180,968 - 32,181,635 (-)Ensembl
RefSeq Acc Id: ENST00000473619
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl632,180,968 - 32,182,931 (-)Ensembl
RefSeq Acc Id: ENST00000484849
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl632,180,968 - 32,184,246 (-)Ensembl
RefSeq Acc Id: ENST00000488669
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl632,180,968 - 32,182,931 (-)Ensembl
RefSeq Acc Id: ENST00000538695   ⟹   ENSP00000445389
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl632,183,409 - 32,184,322 (-)Ensembl
RefSeq Acc Id: ENST00000620802   ⟹   ENSP00000484081
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl632,180,968 - 32,184,322 (-)Ensembl
RefSeq Acc Id: NM_001136   ⟹   NP_001127
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38632,180,969 - 32,184,253 (-)NCBI
GRCh37632,148,745 - 32,152,099 (-)ENTREZGENE
Build 36632,256,724 - 32,260,001 (-)NCBI Archive
HuRef631,902,943 - 31,906,297 (-)ENTREZGENE
CHM1_1632,151,229 - 32,154,583 (-)NCBI
T2T-CHM13v2.0632,034,160 - 32,037,444 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001206929   ⟹   NP_001193858
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38632,180,969 - 32,184,253 (-)NCBI
GRCh37632,148,745 - 32,152,099 (-)ENTREZGENE
HuRef631,902,943 - 31,906,297 (-)ENTREZGENE
CHM1_1632,151,229 - 32,154,583 (-)NCBI
T2T-CHM13v2.0632,034,160 - 32,037,444 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001206932   ⟹   NP_001193861
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38632,180,969 - 32,184,253 (-)NCBI
GRCh37632,148,745 - 32,152,099 (-)ENTREZGENE
HuRef631,902,943 - 31,906,297 (-)ENTREZGENE
CHM1_1632,151,229 - 32,154,583 (-)NCBI
T2T-CHM13v2.0632,034,160 - 32,037,444 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001206934   ⟹   NP_001193863
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38632,180,969 - 32,184,253 (-)NCBI
GRCh37632,148,745 - 32,152,099 (-)ENTREZGENE
HuRef631,902,943 - 31,906,297 (-)ENTREZGENE
CHM1_1632,151,229 - 32,154,583 (-)NCBI
T2T-CHM13v2.0632,034,160 - 32,037,444 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001206936   ⟹   NP_001193865
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38632,180,969 - 32,184,253 (-)NCBI
GRCh37632,148,745 - 32,152,099 (-)ENTREZGENE
HuRef631,902,943 - 31,906,297 (-)ENTREZGENE
CHM1_1632,151,229 - 32,154,583 (-)NCBI
T2T-CHM13v2.0632,034,160 - 32,037,444 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001206940   ⟹   NP_001193869
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38632,180,969 - 32,184,253 (-)NCBI
GRCh37632,148,745 - 32,152,099 (-)ENTREZGENE
HuRef631,902,943 - 31,906,297 (-)ENTREZGENE
CHM1_1632,151,229 - 32,154,583 (-)NCBI
T2T-CHM13v2.0632,034,160 - 32,037,444 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001206954   ⟹   NP_001193883
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38632,180,969 - 32,184,253 (-)NCBI
GRCh37632,148,745 - 32,152,099 (-)ENTREZGENE
HuRef631,902,943 - 31,906,297 (-)ENTREZGENE
CHM1_1632,151,229 - 32,154,583 (-)NCBI
T2T-CHM13v2.0632,034,160 - 32,037,444 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001206966   ⟹   NP_001193895
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38632,180,969 - 32,184,253 (-)NCBI
GRCh37632,148,745 - 32,152,099 (-)ENTREZGENE
HuRef631,902,943 - 31,906,297 (-)ENTREZGENE
CHM1_1632,151,229 - 32,154,583 (-)NCBI
T2T-CHM13v2.0632,034,160 - 32,037,444 (-)NCBI
Sequence:
RefSeq Acc Id: NM_172197   ⟹   NP_751947
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38632,180,969 - 32,184,253 (-)NCBI
GRCh37632,148,745 - 32,152,099 (-)ENTREZGENE
Build 36632,256,724 - 32,260,001 (-)NCBI Archive
HuRef631,902,943 - 31,906,297 (-)ENTREZGENE
CHM1_1632,151,229 - 32,154,583 (-)NCBI
T2T-CHM13v2.0632,034,160 - 32,037,444 (-)NCBI
Sequence:
RefSeq Acc Id: NR_038190
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38632,180,969 - 32,184,253 (-)NCBI
GRCh37632,148,745 - 32,152,099 (-)ENTREZGENE
HuRef631,902,943 - 31,906,297 (-)ENTREZGENE
CHM1_1632,151,229 - 32,154,583 (-)NCBI
T2T-CHM13v2.0632,034,160 - 32,037,444 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017010328   ⟹   XP_016865817
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38632,180,969 - 32,184,253 (-)NCBI
Sequence:
RefSeq Acc Id: XM_047418260   ⟹   XP_047274216
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38632,181,357 - 32,184,253 (-)NCBI
RefSeq Acc Id: XM_047418261   ⟹   XP_047274217
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38632,181,357 - 32,184,253 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001127 (Get FASTA)   NCBI Sequence Viewer  
  NP_001193858 (Get FASTA)   NCBI Sequence Viewer  
  NP_001193861 (Get FASTA)   NCBI Sequence Viewer  
  NP_001193863 (Get FASTA)   NCBI Sequence Viewer  
  NP_001193865 (Get FASTA)   NCBI Sequence Viewer  
  NP_001193869 (Get FASTA)   NCBI Sequence Viewer  
  NP_001193883 (Get FASTA)   NCBI Sequence Viewer  
  NP_001193895 (Get FASTA)   NCBI Sequence Viewer  
  NP_751947 (Get FASTA)   NCBI Sequence Viewer  
  XP_016865817 (Get FASTA)   NCBI Sequence Viewer  
  XP_047274216 (Get FASTA)   NCBI Sequence Viewer  
  XP_047274217 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA03574 (Get FASTA)   NCBI Sequence Viewer  
  AAB47491 (Get FASTA)   NCBI Sequence Viewer  
  AAD15888 (Get FASTA)   NCBI Sequence Viewer  
  AAD15889 (Get FASTA)   NCBI Sequence Viewer  
  AAG35728 (Get FASTA)   NCBI Sequence Viewer  
  AAH20669 (Get FASTA)   NCBI Sequence Viewer  
  AAQ10685 (Get FASTA)   NCBI Sequence Viewer  
  AAQ10686 (Get FASTA)   NCBI Sequence Viewer  
  AAQ10782 (Get FASTA)   NCBI Sequence Viewer  
  AAX07272 (Get FASTA)   NCBI Sequence Viewer  
  AAX07273 (Get FASTA)   NCBI Sequence Viewer  
  AAX07274 (Get FASTA)   NCBI Sequence Viewer  
  AAX07275 (Get FASTA)   NCBI Sequence Viewer  
  AAX07276 (Get FASTA)   NCBI Sequence Viewer  
  AAX07277 (Get FASTA)   NCBI Sequence Viewer  
  AAX07278 (Get FASTA)   NCBI Sequence Viewer  
  AAX07279 (Get FASTA)   NCBI Sequence Viewer  
  AAX07280 (Get FASTA)   NCBI Sequence Viewer  
  AAX07281 (Get FASTA)   NCBI Sequence Viewer  
  AAZ32412 (Get FASTA)   NCBI Sequence Viewer  
  AAZ32413 (Get FASTA)   NCBI Sequence Viewer  
  AAZ32414 (Get FASTA)   NCBI Sequence Viewer  
  AAZ32415 (Get FASTA)   NCBI Sequence Viewer  
  ABV03807 (Get FASTA)   NCBI Sequence Viewer  
  ACE78167 (Get FASTA)   NCBI Sequence Viewer  
  ACE78168 (Get FASTA)   NCBI Sequence Viewer  
  ACE78169 (Get FASTA)   NCBI Sequence Viewer  
  ACE78170 (Get FASTA)   NCBI Sequence Viewer  
  ACF47652 (Get FASTA)   NCBI Sequence Viewer  
  ACF47653 (Get FASTA)   NCBI Sequence Viewer  
  ACF47654 (Get FASTA)   NCBI Sequence Viewer  
  ACF47655 (Get FASTA)   NCBI Sequence Viewer  
  ACF47656 (Get FASTA)   NCBI Sequence Viewer  
  ACL80027 (Get FASTA)   NCBI Sequence Viewer  
  ADQ42256 (Get FASTA)   NCBI Sequence Viewer  
  ADQ42257 (Get FASTA)   NCBI Sequence Viewer  
  ADQ42258 (Get FASTA)   NCBI Sequence Viewer  
  ADQ42259 (Get FASTA)   NCBI Sequence Viewer  
  ADQ42260 (Get FASTA)   NCBI Sequence Viewer  
  ADQ42261 (Get FASTA)   NCBI Sequence Viewer  
  ADQ42262 (Get FASTA)   NCBI Sequence Viewer  
  ADV92535 (Get FASTA)   NCBI Sequence Viewer  
  ADV92536 (Get FASTA)   NCBI Sequence Viewer  
  ADV92537 (Get FASTA)   NCBI Sequence Viewer  
  AHB30241 (Get FASTA)   NCBI Sequence Viewer  
  AQY76648 (Get FASTA)   NCBI Sequence Viewer  
  AQY76649 (Get FASTA)   NCBI Sequence Viewer  
  AQY76650 (Get FASTA)   NCBI Sequence Viewer  
  AQY76651 (Get FASTA)   NCBI Sequence Viewer  
  AQY76652 (Get FASTA)   NCBI Sequence Viewer  
  BAA05958 (Get FASTA)   NCBI Sequence Viewer  
  BAA89369 (Get FASTA)   NCBI Sequence Viewer  
  BAC65465 (Get FASTA)   NCBI Sequence Viewer  
  BAC65466 (Get FASTA)   NCBI Sequence Viewer  
  BAG35995 (Get FASTA)   NCBI Sequence Viewer  
  BAG60385 (Get FASTA)   NCBI Sequence Viewer  
  CAA10169 (Get FASTA)   NCBI Sequence Viewer  
  CAB43094 (Get FASTA)   NCBI Sequence Viewer  
  CAB43108 (Get FASTA)   NCBI Sequence Viewer  
  CAK32486 (Get FASTA)   NCBI Sequence Viewer  
  EAX03610 (Get FASTA)   NCBI Sequence Viewer  
  EAX03611 (Get FASTA)   NCBI Sequence Viewer  
  Q15109 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001193861   ⟸   NM_001206932
- Peptide Label: isoform 3 precursor
- UniProtKB: Q15109 (UniProtKB/Swiss-Prot),   B4DNX3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_751947   ⟸   NM_172197
- Peptide Label: isoform 7 precursor
- UniProtKB: Q15109 (UniProtKB/Swiss-Prot),   B4DNX3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001193883   ⟸   NM_001206954
- Peptide Label: isoform 8 precursor
- UniProtKB: Q15109 (UniProtKB/Swiss-Prot),   B4DNX3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001193865   ⟸   NM_001206936
- Peptide Label: isoform 5 precursor
- UniProtKB: Q15109 (UniProtKB/Swiss-Prot),   B4DNX3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001127   ⟸   NM_001136
- Peptide Label: isoform 1 precursor
- UniProtKB: Q15109 (UniProtKB/Swiss-Prot),   A0A1U9X785 (UniProtKB/TrEMBL),   B4DNX3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001193895   ⟸   NM_001206966
- Peptide Label: isoform 6 precursor
- UniProtKB: Q15109 (UniProtKB/Swiss-Prot),   B4DNX3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001193869   ⟸   NM_001206940
- Peptide Label: isoform 6 precursor
- UniProtKB: Q15109 (UniProtKB/Swiss-Prot),   B4DNX3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001193858   ⟸   NM_001206929
- Peptide Label: isoform 2 precursor
- UniProtKB: Q15109 (UniProtKB/Swiss-Prot),   B4DNX3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001193863   ⟸   NM_001206934
- Peptide Label: isoform 4 precursor
- UniProtKB: Q15109 (UniProtKB/Swiss-Prot),   B4DNX3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_016865817   ⟸   XM_017010328
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSP00000387887   ⟸   ENST00000438221
RefSeq Acc Id: ENSP00000484081   ⟸   ENST00000620802
RefSeq Acc Id: ENSP00000398466   ⟸   ENST00000450110
RefSeq Acc Id: ENSP00000364196   ⟸   ENST00000375056
RefSeq Acc Id: ENSP00000364195   ⟸   ENST00000375055
RefSeq Acc Id: ENSP00000364208   ⟸   ENST00000375067
RefSeq Acc Id: ENSP00000364206   ⟸   ENST00000375065
RefSeq Acc Id: ENSP00000364210   ⟸   ENST00000375069
RefSeq Acc Id: ENSP00000364211   ⟸   ENST00000375070
RefSeq Acc Id: ENSP00000364217   ⟸   ENST00000375076
RefSeq Acc Id: ENSP00000445389   ⟸   ENST00000538695
RefSeq Acc Id: XP_047274217   ⟸   XM_047418261
- Peptide Label: isoform X3
RefSeq Acc Id: XP_047274216   ⟸   XM_047418260
- Peptide Label: isoform X2
Protein Domains
Ig-like   Ig-like C2-type   Ig-like V-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q15109-F1-model_v2 AlphaFold Q15109 1-404 view protein structure

Promoters
RGD ID:6872772
Promoter ID:EPDNEW_H9551
Type:initiation region
Name:AGER_1
Description:advanced glycosylation end-product specific receptor
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38632,184,253 - 32,184,313EPDNEW
RGD ID:6803738
Promoter ID:HG_KWN:53077
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:HeLa_S3,   K562,   Lymphoblastoid
Transcripts:OTTHUMT00000076204
Position:
Human AssemblyChrPosition (strand)Source
Build 36632,256,901 - 32,258,322 (-)MPROMDB
RGD ID:6803740
Promoter ID:HG_KWN:53078
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   K562,   Lymphoblastoid
Transcripts:OTTHUMT00000268939,   OTTHUMT00000268940
Position:
Human AssemblyChrPosition (strand)Source
Build 36632,258,401 - 32,259,252 (-)MPROMDB
RGD ID:6803749
Promoter ID:HG_KWN:53079
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   HeLa_S3,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000375055,   ENST00000375056,   ENST00000375059,   ENST00000375061,   ENST00000375065,   ENST00000375069,   ENST00000375070,   OTTHUMT00000076200,   OTTHUMT00000076201,   OTTHUMT00000076202,   OTTHUMT00000076203,   OTTHUMT00000268938,   UC003OAM.1,   UC003OAO.1,   UC003OAQ.1,   UC003OAT.1,   UC010JTV.1,   UC010JTW.1
Position:
Human AssemblyChrPosition (strand)Source
Build 36632,259,631 - 32,260,131 (-)MPROMDB
RGD ID:6852566
Promoter ID:EP74095
Type:initiation region
Name:HS_AGER
Description:Advanced glycosylation end product-specific receptor.
SO ACC ID:SO:0000170
Source:EPD (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Mammalian gene collection (MGC) full-length cDNA cloning
Position:
Human AssemblyChrPosition (strand)Source
Build 36632,260,015 - 32,260,075EPD

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 6p25.3-12.3(chr6:156974-46789291)x3 copy number gain See cases [RCV000143497] Chr6:156974..46789291 [GRCh38]
Chr6:156974..46757028 [GRCh37]
Chr6:101974..46864987 [NCBI36]
Chr6:6p25.3-12.3		 pathogenic
GRCh37/hg19 6p21.33-21.32(chr6:32052479-32184403)x3 copy number gain See cases [RCV000239830] Chr6:32052479..32184403 [GRCh37]
Chr6:6p21.33-21.32		 likely pathogenic|uncertain significance
GRCh37/hg19 6p21.33-21.32(chr6:31952482-32243155)x4 copy number gain See cases [RCV000446740] Chr6:31952482..32243155 [GRCh37]
Chr6:6p21.33-21.32		 uncertain significance
GRCh37/hg19 6p25.3-q27(chr6:156975-170919482)x3 copy number gain See cases [RCV000512067] Chr6:156975..170919482 [GRCh37]
Chr6:6p25.3-q27		 pathogenic
GRCh37/hg19 6p25.3-q27(chr6:156975-170919482) copy number gain See cases [RCV000510595] Chr6:156975..170919482 [GRCh37]
Chr6:6p25.3-q27		 pathogenic
GRCh37/hg19 6p22.1-q14.1(chr6:29455465-81447367) copy number gain not provided [RCV000767714] Chr6:29455465..81447367 [GRCh37]
Chr6:6p22.1-q14.1		 pathogenic
GRCh37/hg19 6p25.3-q27(chr6:108666-170980171)x3 copy number gain not provided [RCV000745403] Chr6:108666..170980171 [GRCh37]
Chr6:6p25.3-q27		 pathogenic
GRCh37/hg19 6p25.3-q27(chr6:60107-171054786)x3 copy number gain not provided [RCV000745400] Chr6:60107..171054786 [GRCh37]
Chr6:6p25.3-q27		 pathogenic
GRCh37/hg19 6p25.3-q27(chr6:165632-170919470)x3 copy number gain not provided [RCV000745404] Chr6:165632..170919470 [GRCh37]
Chr6:6p25.3-q27		 pathogenic
NM_001136.5(AGER):c.811T>A (p.Trp271Arg) single nucleotide variant not provided [RCV000881806] Chr6:32182579 [GRCh38]
Chr6:32150356 [GRCh37]
Chr6:6p21.32		 benign|conflicting interpretations of pathogenicity
NM_001136.5(AGER):c.902G>C (p.Cys301Ser) single nucleotide variant not provided [RCV000881805] Chr6:32182309 [GRCh38]
Chr6:32150086 [GRCh37]
Chr6:6p21.32		 benign|conflicting interpretations of pathogenicity
NM_001136.5(AGER):c.243C>T (p.Asn81=) single nucleotide variant not provided [RCV000904731] Chr6:32183667 [GRCh38]
Chr6:32151444 [GRCh37]
Chr6:6p21.32		 likely benign
NM_001136.5(AGER):c.692-9A>C single nucleotide variant not provided [RCV000922439] Chr6:32182707 [GRCh38]
Chr6:32150484 [GRCh37]
Chr6:6p21.32		 likely benign
NM_001136.5(AGER):c.941G>A (p.Arg314His) single nucleotide variant not provided [RCV000966990] Chr6:32182270 [GRCh38]
Chr6:32150047 [GRCh37]
Chr6:6p21.32		 benign
NM_001136.5(AGER):c.975G>A (p.Glu325=) single nucleotide variant not provided [RCV000918517] Chr6:32181622 [GRCh38]
Chr6:32149399 [GRCh37]
Chr6:6p21.32		 likely benign
NM_001136.5(AGER):c.925G>A (p.Gly309Arg) single nucleotide variant not provided [RCV000964471] Chr6:32182286 [GRCh38]
Chr6:32150063 [GRCh37]
Chr6:6p21.32		 likely benign
NM_001136.5(AGER):c.138C>T (p.Pro46=) single nucleotide variant not provided [RCV000919262] Chr6:32183902 [GRCh38]
Chr6:32151679 [GRCh37]
Chr6:6p21.32		 likely benign
GRCh37/hg19 6p21.33-21.32(chr6:32027371-32448599)x3 copy number gain not provided [RCV000846873] Chr6:32027371..32448599 [GRCh37]
Chr6:6p21.33-21.32		 uncertain significance
NM_001136.5(AGER):c.6= (p.Ala2=) variation not provided [RCV000950146] Chr6:32184217 [GRCh38]
Chr6:32151994 [GRCh37]
Chr6:6p21.32		 benign
NM_001136.5(AGER):c.229C>T (p.Arg77Cys) single nucleotide variant not provided [RCV000952525] Chr6:32183681 [GRCh38]
Chr6:32151458 [GRCh37]
Chr6:6p21.32		 benign
NM_001136.5(AGER):c.1106G>A (p.Arg369Gln) single nucleotide variant not provided [RCV000948730] Chr6:32181363 [GRCh38]
Chr6:32149140 [GRCh37]
Chr6:6p21.32		 benign
NM_001136.5(AGER):c.1027C>T (p.Leu343=) single nucleotide variant not provided [RCV000911191] Chr6:32181442 [GRCh38]
Chr6:32149219 [GRCh37]
Chr6:6p21.32		 benign
GRCh37/hg19 6p21.33-21.32(chr6:31916915-32278000)x3 copy number gain not provided [RCV001005792] Chr6:31916915..32278000 [GRCh37]
Chr6:6p21.33-21.32		 uncertain significance
GRCh37/hg19 6p21.33-21.31(chr6:31036397-34088832)x3 copy number gain not provided [RCV001005791] Chr6:31036397..34088832 [GRCh37]
Chr6:6p21.33-21.31		 likely pathogenic
GRCh37/hg19 6p21.33-21.32(chr6:31952482-32243155) copy number gain not specified [RCV002053565] Chr6:31952482..32243155 [GRCh37]
Chr6:6p21.33-21.32		 uncertain significance

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:320 AgrOrtholog
COSMIC AGER COSMIC
Ensembl Genes ENSG00000204305 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSG00000206320 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSG00000229058 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSG00000230514 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSG00000231268 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSG00000234729 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSG00000237405 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSP00000364195 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000364196 UniProtKB/TrEMBL
  ENSP00000364208 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000364210 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000364211 UniProtKB/TrEMBL
  ENSP00000364217 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000372762 UniProtKB/Swiss-Prot
  ENSP00000372766 UniProtKB/Swiss-Prot
  ENSP00000387853 UniProtKB/Swiss-Prot
  ENSP00000387887 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000388041 UniProtKB/TrEMBL
  ENSP00000388462 UniProtKB/Swiss-Prot
  ENSP00000391024 UniProtKB/TrEMBL
  ENSP00000391743 UniProtKB/Swiss-Prot
  ENSP00000391970 UniProtKB/TrEMBL
  ENSP00000394516 UniProtKB/TrEMBL
  ENSP00000395578 UniProtKB/TrEMBL
  ENSP00000395812 UniProtKB/Swiss-Prot
  ENSP00000397227 UniProtKB/Swiss-Prot
  ENSP00000397350 UniProtKB/TrEMBL
  ENSP00000397777 UniProtKB/TrEMBL
  ENSP00000398466 UniProtKB/TrEMBL
  ENSP00000399134 UniProtKB/TrEMBL
  ENSP00000399686 UniProtKB/Swiss-Prot
  ENSP00000400667 UniProtKB/Swiss-Prot
  ENSP00000401068 UniProtKB/Swiss-Prot
  ENSP00000401896 UniProtKB/TrEMBL
  ENSP00000403322 UniProtKB/TrEMBL
  ENSP00000407467 UniProtKB/TrEMBL
  ENSP00000409457 UniProtKB/Swiss-Prot
  ENSP00000410918 UniProtKB/TrEMBL
  ENSP00000411203 UniProtKB/TrEMBL
  ENSP00000411652 UniProtKB/TrEMBL
  ENSP00000412576 UniProtKB/TrEMBL
  ENSP00000413391 UniProtKB/Swiss-Prot
  ENSP00000415144 UniProtKB/Swiss-Prot
  ENSP00000415780 UniProtKB/TrEMBL
  ENSP00000416042 UniProtKB/Swiss-Prot
  ENSP00000445389 UniProtKB/TrEMBL
  ENSP00000446495 UniProtKB/TrEMBL
  ENSP00000446533 UniProtKB/TrEMBL
  ENSP00000446582 UniProtKB/TrEMBL
  ENSP00000446660 UniProtKB/TrEMBL
  ENSP00000446682 UniProtKB/TrEMBL
  ENSP00000446692 UniProtKB/TrEMBL
  ENSP00000446835 UniProtKB/Swiss-Prot
  ENSP00000447095 UniProtKB/TrEMBL
  ENSP00000447301 UniProtKB/Swiss-Prot
  ENSP00000447531 UniProtKB/TrEMBL
  ENSP00000448028 UniProtKB/TrEMBL
  ENSP00000448142 UniProtKB/TrEMBL
  ENSP00000448234 UniProtKB/TrEMBL
  ENSP00000448287 UniProtKB/TrEMBL
  ENSP00000448486 UniProtKB/TrEMBL
  ENSP00000448525 UniProtKB/TrEMBL
  ENSP00000448579 UniProtKB/Swiss-Prot
  ENSP00000448979 UniProtKB/Swiss-Prot
  ENSP00000449037 UniProtKB/TrEMBL
  ENSP00000449040 UniProtKB/TrEMBL
  ENSP00000449042 UniProtKB/Swiss-Prot
  ENSP00000449091 UniProtKB/TrEMBL
  ENSP00000449100 UniProtKB/TrEMBL
  ENSP00000449143 UniProtKB/TrEMBL
  ENSP00000449226 UniProtKB/Swiss-Prot
  ENSP00000449368 UniProtKB/TrEMBL
  ENSP00000449506 UniProtKB/TrEMBL
  ENSP00000449676 UniProtKB/TrEMBL
  ENSP00000449708 UniProtKB/Swiss-Prot
  ENSP00000449731 UniProtKB/TrEMBL
  ENSP00000449754 UniProtKB/TrEMBL
  ENSP00000449769 UniProtKB/TrEMBL
  ENSP00000449931 UniProtKB/TrEMBL
  ENSP00000449997 UniProtKB/TrEMBL
  ENSP00000450134 UniProtKB/Swiss-Prot
  ENSP00000450205 UniProtKB/TrEMBL
  ENSP00000484081 UniProtKB/TrEMBL
Ensembl Transcript ENST00000375055 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000375056 UniProtKB/TrEMBL
  ENST00000375067 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000375069 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000375070 UniProtKB/TrEMBL
  ENST00000375076 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000383275 UniProtKB/Swiss-Prot
  ENST00000383279 UniProtKB/Swiss-Prot
  ENST00000412470 UniProtKB/Swiss-Prot
  ENST00000412794 UniProtKB/TrEMBL
  ENST00000415973 UniProtKB/TrEMBL
  ENST00000416532 UniProtKB/TrEMBL
  ENST00000418313 UniProtKB/TrEMBL
  ENST00000424145 UniProtKB/TrEMBL
  ENST00000424476 UniProtKB/TrEMBL
  ENST00000426138 UniProtKB/Swiss-Prot
  ENST00000426320 UniProtKB/TrEMBL
  ENST00000427822 UniProtKB/Swiss-Prot
  ENST00000432831