Capg (capping actin protein, gelsolin like) - Rat Genome Database

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Gene: Capg (capping actin protein, gelsolin like) Rattus norvegicus
Analyze
Symbol: Capg
Name: capping actin protein, gelsolin like
RGD ID: 1311724
Description: Predicted to enable actin filament binding activity; phosphatidylinositol-4,5-bisphosphate binding activity; and protein domain specific binding activity. Predicted to be involved in several processes, including actin filament severing; actin polymerization or depolymerization; and barbed-end actin filament capping. Predicted to act upstream of or within cellular response to type II interferon. Predicted to be located in several cellular components, including Flemming body; microtubule cytoskeleton; and nuclear lumen. Predicted to be active in actin cytoskeleton and cytoplasm. Orthologous to human CAPG (capping actin protein, gelsolin like); INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: actin regulatory protein CAP-G; capping protein (actin filament), gelsolin-like; LOC297339; macrophage-capping protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84106,152,912 - 106,170,010 (+)NCBIGRCr8
mRatBN7.24104,594,743 - 104,611,856 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4104,594,753 - 104,611,856 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4109,978,942 - 109,990,693 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04105,754,064 - 105,765,815 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04104,367,824 - 104,379,611 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04100,395,693 - 100,419,447 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4100,407,658 - 100,419,446 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04165,172,664 - 165,189,798 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44105,850,321 - 105,862,109 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14106,094,801 - 106,106,589 (+)NCBI
Celera493,752,047 - 93,763,826 (+)NCBICelera
Cytogenetic Map4q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (EXP,ISO)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-methylcholanthrene  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrolein  (ISO)
acrylamide  (EXP,ISO)
actinomycin D  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
amitrole  (EXP)
amphetamine  (EXP)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
benzoates  (ISO)
beta-lapachone  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
butanal  (ISO)
cadmium dichloride  (EXP,ISO)
calcitriol  (ISO)
captan  (ISO)
carbon nanotube  (EXP,ISO)
CGP 52608  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
curcumin  (ISO)
cyclosporin A  (EXP)
diarsenic trioxide  (ISO)
diethylstilbestrol  (ISO)
dioxygen  (ISO)
diquat  (ISO)
diuron  (EXP)
elemental selenium  (ISO)
entinostat  (ISO)
folic acid  (ISO)
folpet  (ISO)
formaldehyde  (ISO)
furan  (EXP)
genistein  (ISO)
glycidol  (EXP)
heparin  (EXP)
hexachlorobenzene  (EXP)
ivermectin  (ISO)
L-methionine  (ISO)
lidocaine  (EXP)
lipopolysaccharide  (ISO)
methapyrilene  (ISO)
methimazole  (EXP)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (EXP)
Nutlin-3  (ISO)
ozone  (ISO)
paracetamol  (ISO)
pentanal  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP,ISO)
PhIP  (EXP)
piperonyl butoxide  (ISO)
piroxicam  (ISO)
potassium dichromate  (ISO)
propanal  (ISO)
quartz  (EXP)
resveratrol  (EXP,ISO)
SB 431542  (ISO)
selenium atom  (ISO)
silicon dioxide  (EXP,ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium dichromate  (EXP,ISO)
sodium fluoride  (ISO)
Soman  (EXP)
streptozocin  (EXP)
sulforaphane  (ISO)
sunitinib  (ISO)
tacrolimus hydrate  (EXP)
tamibarotene  (ISO)
tamoxifen  (ISO)
temozolomide  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
triclosan  (ISO)
triphenyl phosphate  (ISO)
Triptolide  (EXP)
triptonide  (ISO)
troglitazone  (EXP)
urethane  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)
vinclozolin  (EXP)
vincristine  (ISO)
vitamin E  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
actin cytoskeleton  (IBA)
centriole  (IEA,ISO)
cytoplasm  (IBA,IEA,ISO)
Flemming body  (IEA,ISO)
lamellipodium  (IEA)
melanosome  (IEA)
mitotic spindle  (IEA,ISO)
nucleolus  (IEA,ISO)
nucleoplasm  (IEA,ISO)
nucleus  (ISO)
phagocytic vesicle  (ISO)
ruffle  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:11514591   PMID:15489334   PMID:18266911   PMID:18938132   PMID:19056867   PMID:19144319   PMID:19166812   PMID:20458337   PMID:23376485   PMID:23533145   PMID:24006456   PMID:24236012  
PMID:25468996  


Genomics

Comparative Map Data
Capg
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84106,152,912 - 106,170,010 (+)NCBIGRCr8
mRatBN7.24104,594,743 - 104,611,856 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4104,594,753 - 104,611,856 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4109,978,942 - 109,990,693 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04105,754,064 - 105,765,815 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04104,367,824 - 104,379,611 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04100,395,693 - 100,419,447 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4100,407,658 - 100,419,446 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04165,172,664 - 165,189,798 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44105,850,321 - 105,862,109 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14106,094,801 - 106,106,589 (+)NCBI
Celera493,752,047 - 93,763,826 (+)NCBICelera
Cytogenetic Map4q32NCBI
CAPG
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38285,391,602 - 85,419,540 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl285,394,753 - 85,418,432 (-)EnsemblGRCh38hg38GRCh38
GRCh37285,621,876 - 85,641,139 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36285,475,382 - 85,491,187 (-)NCBINCBI36Build 36hg18NCBI36
Build 34285,533,548 - 85,549,132NCBI
Celera285,450,057 - 85,465,950 (-)NCBICelera
Cytogenetic Map2p11.2NCBI
HuRef285,518,680 - 85,537,978 (-)NCBIHuRef
CHM1_1285,551,623 - 85,570,945 (-)NCBICHM1_1
T2T-CHM13v2.0285,393,613 - 85,421,559 (-)NCBIT2T-CHM13v2.0
Capg
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39672,515,265 - 72,539,966 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl672,521,374 - 72,539,966 (+)EnsemblGRCm39 Ensembl
GRCm38672,538,282 - 72,562,983 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl672,544,391 - 72,562,983 (+)EnsemblGRCm38mm10GRCm38
MGSCv37672,494,433 - 72,512,974 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36672,474,046 - 72,492,482 (+)NCBIMGSCv36mm8
Celera674,642,688 - 74,661,043 (+)NCBICelera
Cytogenetic Map6C1NCBI
cM Map632.27NCBI
Capg
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554242,072,035 - 2,080,086 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554242,064,672 - 2,080,192 (+)NCBIChiLan1.0ChiLan1.0
CAPG
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21240,964,633 - 40,988,660 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A40,967,382 - 40,991,422 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A85,447,296 - 85,466,677 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A86,997,891 - 87,022,494 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A86,997,891 - 87,016,263 (-)Ensemblpanpan1.1panPan2
CAPG
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11739,619,429 - 39,640,944 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1739,619,248 - 39,640,942 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1739,299,850 - 39,312,556 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01740,437,759 - 40,450,697 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1740,428,690 - 40,569,097 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11739,504,989 - 39,517,906 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01739,576,662 - 39,589,513 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01739,976,517 - 39,989,441 (+)NCBIUU_Cfam_GSD_1.0
Capg
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629279,054,827 - 79,081,310 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367121,793,480 - 1,806,602 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367121,793,666 - 1,803,621 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CAPG
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl359,339,966 - 59,366,846 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1359,335,483 - 59,366,855 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2362,357,527 - 62,374,580 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103219957
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11421,742,163 - 21,761,462 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1421,746,044 - 21,761,322 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604590,704,559 - 90,730,585 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Capg
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474917,723,715 - 17,746,346 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474917,706,582 - 17,764,087 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Capg
81 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:97
Count of miRNA genes:88
Interacting mature miRNAs:90
Transcripts:ENSRNOT00000018562
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631689Scl4Serum cholesterol level QTL 41.90.008blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)495174120140174120Rat
1582232Gluco25Glucose level QTL 253.60.0023blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)485253748148090731Rat
1358352Srcrt3Stress Responsive Cort QTL 32.29blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)438465774146803430Rat
1578655Bmd11Bone mineral density QTL 1111femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)490850165135850165Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)426775591168368347Rat
1357342Bw40Body weight QTL 400.001body mass (VT:0001259)body weight (CMO:0000012)476647384117676292Rat
631556Bp135Blood pressure QTL 1350.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)478881294117676292Rat
61330Eau1Experimental allergic uveoretinitis QTL 10.0003uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)470362013132642728Rat
70167Bw22Body weight QTL 223.1body mass (VT:0001259)body weight (CMO:0000012)476647384117676292Rat
1549839Bw52Body weight QTL 520.0001body mass (VT:0001259)body weight gain (CMO:0000420)461697658115089733Rat
70177Xhs1X-ray hypersensitivity QTL 125.1intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)482798864152731274Rat
724522Bp146Blood pressure QTL 1462.20.0021arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)473630210118630210Rat
61476Aia3Adjuvant induced arthritis QTL 33.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)486730991131730991Rat
1641919Alc22Alcohol consumption QTL 220.0005drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)481192555126192555Rat
2300179Bmd50Bone mineral density QTL 505.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)460928534105928534Rat
1354660Salc1Saline consumption QTL 111.26drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)444463908148090542Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)462933508114921294Rat
1298082Stresp4Stress response QTL 4blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)450119848146803430Rat
1578670Bss14Bone structure and strength QTL 1416.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)487327165132327165Rat
2317588Eae27Experimental allergic encephalomyelitis QTL 27nervous system integrity trait (VT:0010566)percentage of study population developing experimental autoimmune encephalomyelitis during a period of time (CMO:0001047)4103194805112478794Rat
1300139Hrtrt6Heart rate QTL 62.85heart pumping trait (VT:2000009)heart rate (CMO:0000002)439524264116179656Rat
70200Alc18Alcohol consumption QTL 189.2drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)456647873149491524Rat
1578657Bss12Bone structure and strength QTL 128.9femur morphology trait (VT:0000559)femoral neck cross-sectional area (CMO:0001697)460220938105220938Rat
1578658Bss13Bone structure and strength QTL 138femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)460220938105220938Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)411320076180699135Rat
1578662Bss15Bone structure and strength QTL 1519.6femur width (VT:1000666)femoral neck width (CMO:0001695)487327165132327165Rat
6478684Anxrr30Anxiety related response QTL 300.00087defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)462753847107753847Rat
2302051Pia28Pristane induced arthritis QTL 285.30.001blood autoantibody amount (VT:0003725)serum immunoglobulin G-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002112)473630210118630210Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)459948935154902892Rat
738015Pia9Pristane induced arthritis QTL 94.50.048joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)480694870125694870Rat
2312567Glom19Glomerulus QTL 191.90.006kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)445456990146803430Rat
634335Anxrr16Anxiety related response QTL 167.22locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)493308457167139447Rat
6478772Anxrr49Anxiety related response QTL 490.15488defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)462753847107753847Rat
631646Stl4Serum triglyceride level QTL 46.50.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)473169846132642728Rat
634334Xhs3X-ray hypersensitivity QTL 310intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)484728680129854654Rat
1354612Foco1Food consumption QTL 18.87eating behavior trait (VT:0001431)food intake rate (CMO:0000427)444463908148090542Rat
634344Hcar7Hepatocarcinoma resistance QTL 77.8liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)470808386115808386Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45214602146446691Rat
738031Alc14Alcohol consumption QTL 147.60.00003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)459948935154902892Rat
1576316Ept5Estrogen-induced pituitary tumorigenesis QTL 53.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)483428419177635233Rat
631662Hcar2Hepatocarcinoma resistance QTL 23.10.0003liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)478878504123878504Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)444463720155883716Rat
631651Bp124Blood pressure QTL 1243arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)462879517107879517Rat
61418Pia5Pristane induced arthritis QTL 54.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)462277855128289560Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)459948935154902892Rat
1358202Gluco11Glucose level QTL 112.40.02adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)485379421167139601Rat
1641833Alc21Alcohol consumption QTL 218.60.0001drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)456698790126192555Rat
2306899Bp338Blood pressure QTL 3380.071arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)481006124120102625Rat
631674Iddm14Insulin dependent diabetes mellitus QTL 14blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)464528739157573521Rat
6478743Anxrr40Anxiety related response QTL 400.83076defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)462753847107753847Rat
12798523Anxrr56Anxiety related response QTL 562.830.05locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)485253748150276390Rat
61434Cia3Collagen induced arthritis QTL 34.8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4103194656148194656Rat
12798520Anxrr55Anxiety related response QTL 554.450.01locomotor behavior trait (VT:0001392)number of rearing movements with lid-pushing in an experimental apparatus (CMO:0002715)432583980114627242Rat

Markers in Region
UniSTS:498461  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23162,246,377 - 162,246,414 (-)MAPPERmRatBN7.2
mRatBN7.24104,606,177 - 104,606,247 (+)MAPPERmRatBN7.2
Rnor_6.04100,413,771 - 100,413,840NCBIRnor6.0
Rnor_5.04165,184,122 - 165,184,191UniSTSRnor5.0
RGSC_v3.44105,856,434 - 105,856,503UniSTSRGSC3.4
Celera493,758,151 - 93,758,220UniSTS
Cytogenetic Map4q33UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000018562   ⟹   ENSRNOP00000018562
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4104,601,484 - 104,611,856 (+)Ensembl
Rnor_6.0 Ensembl4100,407,658 - 100,419,446 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000102328   ⟹   ENSRNOP00000096107
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4104,594,753 - 104,611,855 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000108841   ⟹   ENSRNOP00000087979
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4104,600,282 - 104,611,856 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000116665   ⟹   ENSRNOP00000094307
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4104,605,634 - 104,611,856 (+)Ensembl
RefSeq Acc Id: NM_001013086   ⟹   NP_001013104
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84106,158,222 - 106,170,010 (+)NCBI
mRatBN7.24104,600,062 - 104,611,856 (+)NCBI
Rnor_6.04100,407,658 - 100,419,447 (+)NCBI
Rnor_5.04165,172,664 - 165,189,798 (+)NCBI
RGSC_v3.44105,850,321 - 105,862,109 (+)RGD
Celera493,752,047 - 93,763,826 (+)RGD
Sequence:
RefSeq Acc Id: XM_006236661   ⟹   XP_006236723
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84106,152,912 - 106,170,010 (+)NCBI
mRatBN7.24104,594,743 - 104,611,856 (+)NCBI
Rnor_6.04100,402,266 - 100,419,447 (+)NCBI
Rnor_5.04165,172,664 - 165,189,798 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006236663   ⟹   XP_006236725
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84106,158,475 - 106,170,010 (+)NCBI
mRatBN7.24104,600,274 - 104,611,856 (+)NCBI
Rnor_6.04100,407,687 - 100,419,447 (+)NCBI
Rnor_5.04165,172,664 - 165,189,798 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039107320   ⟹   XP_038963248
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84106,159,627 - 106,170,010 (+)NCBI
mRatBN7.24104,601,543 - 104,611,856 (+)NCBI
RefSeq Acc Id: XM_039107321   ⟹   XP_038963249
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84106,158,801 - 106,170,010 (+)NCBI
mRatBN7.24104,600,638 - 104,611,856 (+)NCBI
RefSeq Acc Id: NP_001013104   ⟸   NM_001013086
- UniProtKB: Q6AYC4 (UniProtKB/Swiss-Prot),   A6IAC6 (UniProtKB/TrEMBL),   A0A8I6A6Z2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006236723   ⟸   XM_006236661
- Peptide Label: isoform X2
- UniProtKB: Q6AYC4 (UniProtKB/Swiss-Prot),   A6IAC6 (UniProtKB/TrEMBL),   A0A8I6A6Z2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006236725   ⟸   XM_006236663
- Peptide Label: isoform X2
- UniProtKB: Q6AYC4 (UniProtKB/Swiss-Prot),   A6IAC6 (UniProtKB/TrEMBL),   A0A8I6A6Z2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000018562   ⟸   ENSRNOT00000018562
RefSeq Acc Id: XP_038963249   ⟸   XM_039107321
- Peptide Label: isoform X2
- UniProtKB: Q6AYC4 (UniProtKB/Swiss-Prot),   A6IAC6 (UniProtKB/TrEMBL),   A0A8I6A6Z2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038963248   ⟸   XM_039107320
- Peptide Label: isoform X1
- UniProtKB: A0A8L2Q9I9 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000094307   ⟸   ENSRNOT00000116665
Ensembl Acc Id: ENSRNOP00000087979   ⟸   ENSRNOT00000108841
Ensembl Acc Id: ENSRNOP00000096107   ⟸   ENSRNOT00000102328
Protein Domains
Gelsolin-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6AYC4-F1-model_v2 AlphaFold Q6AYC4 1-349 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693129
Promoter ID:EPDNEW_R3654
Type:initiation region
Name:Capg_1
Description:capping actin protein, gelsolin like
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.04100,407,894 - 100,407,954EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311724 AgrOrtholog
BioCyc Gene G2FUF-44143 BioCyc
Ensembl Genes ENSRNOG00000013668 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000018562.5 UniProtKB/TrEMBL
  ENSRNOT00000102328.1 UniProtKB/Swiss-Prot
  ENSRNOT00000108841.1 UniProtKB/TrEMBL
  ENSRNOT00000116665.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.20.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7125038 IMAGE-MGC_LOAD
InterPro ADF-H/Gelsolin-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Gelsolin-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Villin/Gelsolin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:297339 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:94092 IMAGE-MGC_LOAD
NCBI Gene 297339 ENTREZGENE
PANTHER MACROPHAGE-CAPPING PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11977 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Gelsolin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Capg PhenoGen
PRINTS GELSOLIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000013668 RatGTEx
SMART GEL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Actin depolymerizing proteins UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6A6Z2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ALX4_RAT UniProtKB/TrEMBL
  A0A8L2Q9I9 ENTREZGENE, UniProtKB/TrEMBL
  A6IAC6 ENTREZGENE, UniProtKB/TrEMBL
  A6IAC7_RAT UniProtKB/TrEMBL
  CAPG_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-01-27 Capg  capping actin protein, gelsolin like  Capg  capping protein (actin filament), gelsolin-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Capg  capping protein (actin filament), gelsolin-like  Capg_predicted  capping protein (actin filament), gelsolin-like (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Capg_predicted  capping protein (actin filament), gelsolin-like (predicted)      Symbol and Name status set to approved 70820 APPROVED