Ndufa10 (NADH:ubiquinone oxidoreductase subunit A10) - Rat Genome Database
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Gene: Ndufa10 (NADH:ubiquinone oxidoreductase subunit A10) Rattus norvegicus
Analyze
Symbol: Ndufa10
Name: NADH:ubiquinone oxidoreductase subunit A10
RGD ID: 727968
Description: Predicted to have NADH dehydrogenase (ubiquinone) activity. Involved in response to drug. Predicted to localize to mitochondrial respiratory chain complex I. Human ortholog(s) of this gene implicated in mitochondrial complex I deficiency. Orthologous to human NDUFA10 (NADH:ubiquinone oxidoreductase subunit A10); PARTICIPATES IN Alzheimer's disease pathway; Huntington's disease pathway; oxidative phosphorylation pathway; INTERACTS WITH 2,2,2-tetramine; 2,5-hexanedione; 3-chloropropane-1,2-diol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CI-42kD; complex I-42kD; hypothetical protein LOC678759; LOC678759; MGC112575; MGC72603; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 10; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial; NADH-ubiquinone oxidoreductase 42 kDa subunit; ndufa10l
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2993,007,034 - 93,041,825 (-)NCBI
Rnor_6.0 Ensembl999,617,052 - 99,651,813 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0999,617,051 - 99,651,827 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0999,282,165 - 99,316,943 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4991,655,135 - 91,689,653 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1991,859,903 - 91,894,383 (-)NCBI
Celera990,544,387 - 90,579,150 (-)NCBICelera
Cytogenetic Map9q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:9125149   PMID:12611891   PMID:14651853   PMID:15489334   PMID:15632090   PMID:17634366   PMID:18614015   PMID:24652937   PMID:26648553   PMID:27626371   PMID:29476059  


Genomics

Comparative Map Data
Ndufa10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2993,007,034 - 93,041,825 (-)NCBI
Rnor_6.0 Ensembl999,617,052 - 99,651,813 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0999,617,051 - 99,651,827 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0999,282,165 - 99,316,943 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4991,655,135 - 91,689,653 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1991,859,903 - 91,894,383 (-)NCBI
Celera990,544,387 - 90,579,150 (-)NCBICelera
Cytogenetic Map9q36NCBI
NDUFA10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2239,892,450 - 240,025,743 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl2239,892,450 - 240,025,345 (-)EnsemblGRCh38hg38GRCh38
GRCh382239,892,442 - 240,025,343 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372240,831,859 - 240,964,759 (-)NCBIGRCh37GRCh37hg19GRCh37
GRCh372240,896,789 - 240,964,819 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362240,548,829 - 240,613,471 (-)NCBINCBI36hg18NCBI36
Build 342240,620,147 - 240,684,788NCBI
Celera2234,570,056 - 234,638,352 (-)NCBI
Cytogenetic Map2q37.3NCBI
HuRef2232,654,836 - 232,722,773 (-)NCBIHuRef
CHM1_12240,837,914 - 240,970,868 (-)NCBICHM1_1
Ndufa10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39192,367,208 - 92,401,547 (-)NCBIGRCm39mm39
GRCm38192,439,486 - 92,473,825 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl192,439,010 - 92,473,860 (-)EnsemblGRCm38mm10GRCm38
MGSCv37194,336,285 - 94,370,335 (-)NCBIGRCm37mm9NCBIm37
MGSCv36194,270,114 - 94,304,164 (-)NCBImm8
Celera195,379,073 - 95,413,122 (-)NCBICelera
Cytogenetic Map1DNCBI
Ndufa10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555421,329,212 - 1,370,695 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555421,329,802 - 1,370,109 (+)NCBIChiLan1.0ChiLan1.0
NDUFA10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12B246,022,168 - 246,085,828 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B246,022,168 - 246,087,658 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02B127,204,900 - 127,269,478 (-)NCBIMhudiblu_PPA_v0panPan3
NDUFA10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2549,920,894 - 49,968,901 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12549,920,748 - 49,968,966 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Ndufa10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049367451,436,257 - 1,471,785 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NDUFA10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15138,999,174 - 139,031,897 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115138,999,174 - 139,031,892 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215153,792,416 - 153,825,373 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NDUFA10
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110126,018,383 - 126,082,847 (-)NCBI
ChlSab1.1 Ensembl10126,015,852 - 126,083,082 (-)Ensembl
Ndufa10
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248474,371,264 - 4,412,334 (-)NCBI

Position Markers
AI548120  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0999,624,139 - 99,624,241NCBIRnor6.0
Rnor_5.0999,289,253 - 99,289,355UniSTSRnor5.0
RGSC_v3.4991,661,974 - 91,662,076UniSTSRGSC3.4
Celera990,551,479 - 90,551,581UniSTS
RH 3.4 Map9798.0UniSTS
Cytogenetic Map9q36UniSTS
RH129838  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0999,617,129 - 99,617,308NCBIRnor6.0
Rnor_6.0662,796,523 - 62,796,703NCBIRnor6.0
Rnor_5.0999,282,243 - 99,282,422UniSTSRnor5.0
Rnor_5.0672,382,087 - 72,382,267UniSTSRnor5.0
RGSC_v3.4662,280,404 - 62,280,584UniSTSRGSC3.4
Celera990,544,465 - 90,544,644UniSTS
Celera658,896,098 - 58,896,278UniSTS
Cytogenetic Map6q21UniSTS
Cytogenetic Map9q36UniSTS
Ndufa10  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0662,797,307 - 62,798,206NCBIRnor6.0
Rnor_5.0672,382,871 - 72,383,770UniSTSRnor5.0
RGSC_v3.4662,281,188 - 62,282,087UniSTSRGSC3.4
Celera658,896,882 - 58,897,781UniSTS
Cytogenetic Map9q36UniSTS
Cytogenetic Map6q21UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
724544Uae9Urinary albumin excretion QTL 94.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)929075079122095297Rat
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)929466970107878528Rat
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)941261034102531865Rat
1578760Cm53Cardiac mass QTL 533.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)961186278106186278Rat
724515Uae16Urinary albumin excretion QTL 168urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)963270073107878387Rat
1300134Bp185Blood pressure QTL 1853.73arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)966757444112943287Rat
1581580Uae34Urinary albumin excretion QTL 34urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)96745166499920892Rat
1578757Pur6Proteinuria QTL 63.30.005total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)96745166499920892Rat
61385Edpm9Estrogen-dependent pituitary mass QTL 93.430.05pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)970241351115241351Rat
731171Glom6Glomerulus QTL 62.80.0003kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)970942881115942881Rat
1354626Bvd1Brain ventricular dilatation QTL 13.730.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)981411073119983851Rat
724547Cm21Cardiac mass QTL 212.7heart mass (VT:0007028)calculated heart weight (CMO:0000073)983686153111609081Rat
4889852Pur26Proteinuria QTL 26150.001total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)990024661107199079Rat
7794784Mcs31Mammary carcinoma susceptibility QTL 312.98mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)990024661119983851Rat
1582203Gluco19Glucose level QTL 193.30.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)999041068107878528Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:108
Count of miRNA genes:86
Interacting mature miRNAs:101
Transcripts:ENSRNOT00000022089
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000022089   ⟹   ENSRNOP00000022089
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl999,617,052 - 99,651,813 (-)Ensembl
RefSeq Acc Id: NM_199495   ⟹   NP_955789
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2993,007,034 - 93,041,801 (-)NCBI
Rnor_6.0999,617,051 - 99,651,813 (-)NCBI
Rnor_5.0999,282,165 - 99,316,943 (-)NCBI
RGSC_v3.4991,655,135 - 91,689,653 (-)RGD
Celera990,544,387 - 90,579,150 (-)RGD
Sequence:
RefSeq Acc Id: XM_008767385   ⟹   XP_008765607
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2993,014,058 - 93,041,825 (-)NCBI
Rnor_6.0999,624,070 - 99,651,827 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017596634   ⟹   XP_017452123
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0999,628,753 - 99,651,827 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017596635   ⟹   XP_017452124
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2993,016,711 - 93,041,825 (-)NCBI
Rnor_6.0999,627,305 - 99,651,827 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039084194   ⟹   XP_038940122
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2993,007,034 - 93,041,825 (-)NCBI
RefSeq Acc Id: XM_039084195   ⟹   XP_038940123
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2993,007,034 - 93,041,555 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_955789   ⟸   NM_199495
- Peptide Label: precursor
- UniProtKB: Q561S0 (UniProtKB/Swiss-Prot),   Q6P6W6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008765607   ⟸   XM_008767385
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017452124   ⟸   XM_017596635
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017452123   ⟸   XM_017596634
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSRNOP00000022089   ⟸   ENSRNOT00000022089
RefSeq Acc Id: XP_038940122   ⟸   XM_039084194
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038940123   ⟸   XM_039084195
- Peptide Label: isoform X3
Protein Domains
dNK

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696866
Promoter ID:EPDNEW_R7390
Type:initiation region
Name:Ndufa10l1_1
Description:NADH dehydrogenase 1 alpha subcomplex 10-like 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R5099  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0999,651,786 - 99,651,846EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Damaging Variants


Assembly: Rnor_6.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
9 99658540 99658541 C T snv WN/N (MCW)
9 99666908 99666909 C T snv WKY/Gcrc (RGD), SHR/NHsd (RGD)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:727968 AgrOrtholog
Ensembl Genes ENSRNOG00000016470 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSRNOP00000022089 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000022089 ENTREZGENE, UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:5599238 IMAGE-MGC_LOAD
  IMAGE:7389276 IMAGE-MGC_LOAD
InterPro DNK_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NDUFA10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:316632 UniProtKB/Swiss-Prot
  rno:678759 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:112575 IMAGE-MGC_LOAD
  MGC:72603 IMAGE-MGC_LOAD
NCBI Gene 678759 ENTREZGENE
Pfam dNK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ndufa10 PhenoGen
PIRSF NADH_UQ_42KD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt NDUAA_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q6P6W6 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary Q80WE0 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-17 Ndufa10  NADH:ubiquinone oxidoreductase subunit A10  Ndufa10  NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 10  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-10-01 Ndufa10  NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 10  Ndufa10l  NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 10-like  Symbol and Name updated 1299863 APPROVED
2008-05-12 Ndufa10l  NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 10-like  Ndufa10  NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 10  Symbol and Name updated 1299863 APPROVED
2008-03-18 Ndufa10  NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 10  LOC678759  hypothetical protein LOC678759  Data Merged 737654 APPROVED
2008-03-18 Ndufa10  NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 10  Ndufa10l  NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 10-like  Symbol and Name updated 1299863 APPROVED
2008-03-13 Ndufa10l  NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 10-like  Ndufa10  NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 10  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-20 LOC678759  hypothetical protein LOC678759      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-07-08 Ndufa10  NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 10      Symbol and Name status set to approved 1299863 APPROVED