(+)-dexrazoxane multiple interactions ISO RGD:731442 6480464 [Doxorubicin co-treated with Dexrazoxane] results in decreased expression of CASP12 mRNA CTD PMID:26873546 (+)-pilocarpine multiple interactions EXP 6480464 [Pilocarpine co-treated with Lithium] results in increased expression of CASP12 mRNA more ... CTD PMID:21429313 (+)-Tetrandrine increases cleavage ISO RGD:1348077 6480464 tetrandrine results in increased cleavage of CASP12 protein CTD PMID:26822499 (R)-noradrenaline multiple interactions EXP 6480464 CAT protein inhibits the reaction [Norepinephrine results in increased cleavage of CASP12 protein alternative form] CTD PMID:16338971 (R)-noradrenaline increases cleavage EXP 6480464 Norepinephrine results in increased cleavage of CASP12 protein alternative form CTD PMID:16338971 (S)-nicotine multiple interactions EXP 6480464 Nicotine inhibits the reaction [Tunicamycin results in increased activity of CASP12 protein] CTD PMID:18477628 (S)-nicotine multiple interactions ISO RGD:731442 6480464 [Nicotine co-treated with 1-Methyl-4-phenyl-1 more ... CTD PMID:20230807 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane multiple interactions EXP 6480464 2 more ... CTD PMID:19414516 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane increases expression EXP 6480464 o, p'-DDT results in increased expression of CASP12 mRNA CTD PMID:22937105 1,1-dichloroethene increases expression ISO RGD:731442 6480464 vinylidene chloride results in increased expression of CASP12 mRNA CTD PMID:26682919 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine increases expression ISO RGD:731442 6480464 1-Methyl-4-phenyl-1 more ... CTD PMID:20230807 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine increases cleavage ISO RGD:731442 6480464 1-Methyl-4-phenyl-1 more ... CTD PMID:24140863 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine multiple interactions ISO RGD:1348077 6480464 TXN protein inhibits the reaction [1-Methyl-4-phenyl-1 more ... CTD PMID:24140863 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine multiple interactions ISO RGD:731442 6480464 [Nicotine co-treated with 1-Methyl-4-phenyl-1 more ... CTD PMID:20230807 1-naphthyl isothiocyanate increases expression EXP 6480464 1-Naphthylisothiocyanate results in increased expression of CASP12 mRNA CTD PMID:25380136 17beta-estradiol multiple interactions EXP 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of CASP12 mRNA CTD PMID:32741896 17beta-estradiol 3-benzoate multiple interactions EXP 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of CASP12 mRNA CTD PMID:32741896 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO RGD:1348077 6480464 2 more ... CTD PMID:19022289 2,2',4,4',5,5'-hexachlorobiphenyl increases expression EXP 6480464 2 more ... CTD PMID:19576244 2,2',4,4',5,5'-hexachlorobiphenyl increases expression ISO RGD:1348077 6480464 2 more ... CTD PMID:19022289 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions EXP 6480464 2 more ... CTD PMID:19576244 2,2',4,4'-Tetrabromodiphenyl ether increases expression ISO RGD:1348077 6480464 2 more ... CTD PMID:19022289 2,2',4,4'-Tetrabromodiphenyl ether multiple interactions EXP 6480464 2 more ... CTD PMID:19576244 2,2',4,4'-Tetrabromodiphenyl ether increases expression EXP 6480464 2 more ... CTD PMID:19576244 , PMID:30029115 2,2',4,4'-Tetrabromodiphenyl ether multiple interactions ISO RGD:1348077 6480464 2 more ... CTD PMID:19022289 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:731442 6480464 Tetrachlorodibenzodioxin affects the expression of CASP12 mRNA CTD PMID:21570461 2,4,6-trinitrobenzenesulfonic acid multiple interactions EXP 6480464 Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP12 protein modified form], Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased cleavage of CASP12 protein] CTD PMID:30503585 2,4,6-trinitrobenzenesulfonic acid increases cleavage EXP 6480464 Trinitrobenzenesulfonic Acid results in increased cleavage of CASP12 protein CTD PMID:30503585 2,4-dinitrotoluene affects expression EXP 6480464 2, 4-dinitrotoluene affects the expression of CASP12 mRNA CTD PMID:21346803 2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile multiple interactions ISO RGD:1348077 6480464 [Verapamil co-treated with Ruthenium Red co-treated with 2-aminoethoxydiphenyl borate] inhibits the reaction [Trichlorfon results in increased cleavage of and results in increased activity of CASP12 protein] CTD PMID:19631781 2-aminoethoxydiphenylborane multiple interactions EXP 6480464 2-aminoethoxydiphenylborane inhibits the reaction [cadmium acetate results in increased cleavage of CASP12 protein] CTD PMID:29883672 3,3',4,4',5-pentachlorobiphenyl multiple interactions EXP 6480464 [3 more ... CTD PMID:30744511 3,3',5,5'-tetrabromobisphenol A decreases expression ISO RGD:731442 6480464 tetrabromobisphenol A results in decreased expression of CASP12 mRNA CTD PMID:25172293 3,4,5,3',4',5'-Hexachlorobiphenyl multiple interactions EXP 6480464 [3 more ... CTD PMID:30744511 3-chloropropane-1,2-diol multiple interactions EXP 6480464 4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased expression of and results in increased cleavage of CASP12 protein], alpha-Chlorohydrin results in increased expression of and results in increased cleavage of CASP12 protein CTD PMID:33651226 3-chloropropane-1,2-diol multiple interactions ISO RGD:1348077 6480464 4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased expression of and results in increased cleavage of CASP12 protein], alpha-Chlorohydrin results in increased expression of and results in increased cleavage of CASP12 protein CTD PMID:33651226 4,4'-diaminodiphenylmethane increases expression EXP 6480464 4, 4'-diaminodiphenylmethane results in increased expression of CASP12 mRNA CTD PMID:25380136 4,4'-sulfonyldiphenol increases expression ISO RGD:731442 6480464 bis(4-hydroxyphenyl)sulfone results in increased expression of CASP12 mRNA CTD PMID:30951980 4-aminophenol multiple interactions EXP 6480464 4-aminophenol results in increased activity of and results in increased cleavage of CASP12 protein more ... CTD PMID:17567590 , PMID:17567592 4-phenylbutyric acid multiple interactions ISO RGD:731442 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [4-phenylbutyric acid inhibits the reaction [4-methyl-2 more ... CTD PMID:17459145 more ... 4-phenylbutyric acid multiple interactions ISO RGD:1348077 6480464 4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased expression of and results in increased cleavage of CASP12 protein] more ... CTD PMID:28245985 , PMID:33651226 4-phenylbutyric acid multiple interactions EXP 6480464 4-phenylbutyric acid inhibits the reaction [4-methyl-2 more ... CTD PMID:33651226 , PMID:33922211 acetamide increases expression EXP 6480464 acetamide results in increased expression of CASP12 mRNA CTD PMID:31881176 acrylamide decreases expression ISO RGD:731442 6480464 Acrylamide results in decreased expression of CASP12 mRNA CTD PMID:21319176 acrylamide increases expression ISO RGD:731442 6480464 Acrylamide results in increased expression of CASP12 mRNA CTD PMID:30807115 acrylonitrile increases expression ISO RGD:1348077 6480464 Acrylonitrile results in increased expression of CASP12 protein CTD PMID:33132245 aflatoxin B1 decreases methylation ISO RGD:1348077 6480464 Aflatoxin B1 results in decreased methylation of CASP12 gene CTD PMID:27153756 agomelatine multiple interactions EXP 6480464 agomelatine inhibits the reaction [Dietary Fats results in increased cleavage of CASP12 protein], agomelatine inhibits the reaction [Galactose results in increased expression of CASP12 protein] CTD PMID:34081941 , PMID:34673010 aldehydo-D-glucose increases cleavage ISO RGD:731442 6480464 Glucose results in increased cleavage of CASP12 protein CTD PMID:30076216 aldehydo-D-glucose multiple interactions EXP 6480464 Chlorogenic Acid inhibits the reaction [Glucose results in increased expression of CASP12 protein] CTD PMID:34801538 aldehydo-D-glucose increases expression EXP 6480464 Glucose results in increased expression of CASP12 protein CTD PMID:34801538 aldehydo-D-glucose multiple interactions ISO RGD:731442 6480464 TRPM7 protein affects the reaction [Glucose results in increased cleavage of CASP12 protein], waixenicin A inhibits the reaction [Glucose results in increased cleavage of CASP12 protein] CTD PMID:30076216 all-trans-retinoic acid multiple interactions ISO RGD:1348077 6480464 [Tretinoin co-treated with Paclitaxel] results in increased expression of CASP12 protein CTD PMID:17701358 all-trans-retinoic acid decreases expression ISO RGD:731442 6480464 Tretinoin results in decreased expression of CASP12 mRNA CTD PMID:22498432 alpha-D-galactose multiple interactions EXP 6480464 agomelatine inhibits the reaction [Galactose results in increased expression of CASP12 protein], Melatonin inhibits the reaction [Galactose results in increased expression of CASP12 protein] CTD PMID:34673010 alpha-D-galactose increases expression EXP 6480464 Galactose results in increased expression of CASP12 protein CTD PMID:34673010 alpha-naphthoflavone increases cleavage ISO RGD:731442 6480464 alpha-naphthoflavone results in increased cleavage of CASP12 protein CTD PMID:30508555 aluminium atom multiple interactions ISO RGD:731442 6480464 [aluminum chloride results in increased abundance of Aluminum] which results in increased expression of CASP12 mRNA CTD PMID:29635646 aluminium(0) multiple interactions ISO RGD:731442 6480464 [aluminum chloride results in increased abundance of Aluminum] which results in increased expression of CASP12 mRNA CTD PMID:29635646 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of CASP12 mRNA CTD PMID:16483693 ammonium chloride increases expression EXP 6480464 Ammonium Chloride results in increased expression of CASP12 protein CTD PMID:16483693 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions EXP 6480464 pyrazolanthrone inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased cleavage of CASP12 protein] CTD PMID:24140863 apigenin multiple interactions ISO RGD:731442 6480464 Apigenin inhibits the reaction [Brefeldin A results in increased activity of CASP12 protein], Apigenin inhibits the reaction [Thapsigargin results in increased activity of CASP12 protein] CTD PMID:20493918 arsenic acid increases activity EXP 6480464 arsenic acid results in increased activity of CASP12 protein CTD PMID:18226606 arsenite(3-) multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [arsenite results in increased activity of CASP12 protein] more ... CTD PMID:18077580 , PMID:18226606 arsenite(3-) multiple interactions ISO RGD:731442 6480464 CALR protein affects the reaction [arsenite results in increased cleavage of CASP12 protein] CTD PMID:32443253 arsenite(3-) increases cleavage ISO RGD:731442 6480464 arsenite results in increased cleavage of CASP12 protein CTD PMID:32443253 arsenite(3-) increases expression ISO RGD:1348077 6480464 arsenite results in increased expression of CASP12 protein CTD PMID:26677073 arsenite(3-) increases activity EXP 6480464 arsenite results in increased activity of CASP12 protein CTD PMID:18077580 , PMID:18226606 arsenous acid multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased cleavage of CASP12 protein] CTD PMID:21145380 arsenous acid increases expression ISO RGD:1348077 6480464 Arsenic Trioxide results in increased expression of CASP12 mRNA CTD PMID:22959511 arsenous acid increases cleavage EXP 6480464 Arsenic Trioxide results in increased cleavage of CASP12 protein CTD PMID:21145380 arsenous acid multiple interactions ISO RGD:1348077 6480464 Arsenic Trioxide promotes the reaction [tetraarsenic tetrasulfide results in increased cleavage of CASP12 protein] more ... CTD PMID:22959511 more ... arsenous acid multiple interactions ISO RGD:731442 6480464 2-aminoethoxydiphenyl borate inhibits the reaction [Arsenic Trioxide results in increased cleavage of CASP12 protein] more ... CTD PMID:24157283 more ... arsenous acid increases cleavage ISO RGD:731442 6480464 Arsenic Trioxide results in increased cleavage of CASP12 protein CTD PMID:27461142 arsenous acid increases expression EXP 6480464 Arsenic Trioxide results in increased expression of CASP12 mRNA, Arsenic Trioxide results in increased expression of CASP12 protein modified form CTD PMID:19730151 , PMID:23664956 arsenous acid increases degradation ISO RGD:731442 6480464 Arsenic Trioxide results in increased degradation of CASP12 protein CTD PMID:24157283 arsenous acid increases expression ISO RGD:731442 6480464 Arsenic Trioxide results in increased expression of CASP12 protein modified form CTD PMID:23664956 , PMID:27638049 arsenous acid increases cleavage ISO RGD:1348077 6480464 Arsenic Trioxide results in increased cleavage of CASP12 protein CTD PMID:19695276 , PMID:26110921 BAPTA multiple interactions ISO RGD:1348077 6480464 1 more ... CTD PMID:28181380 BAPTA increases expression ISO RGD:1348077 6480464 1 more ... CTD PMID:28181380 benzo[a]pyrene increases methylation ISO RGD:1348077 6480464 Benzo(a)pyrene results in increased methylation of CASP12 promoter CTD PMID:27901495 benzo[e]pyrene increases activity EXP 6480464 benzo(e)pyrene results in increased activity of CASP12 protein CTD PMID:19899995 benzo[e]pyrene increases activity ISO RGD:1348077 6480464 benzo(e)pyrene results in increased activity of CASP12 protein CTD PMID:18586875 bisphenol A increases expression ISO RGD:731442 6480464 bisphenol A results in increased expression of CASP12 mRNA CTD PMID:20807545 more ... bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of CASP12 mRNA CTD PMID:34947998 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of CASP12 mRNA CTD PMID:25181051 , PMID:33296240 bisphenol F increases expression ISO RGD:731442 6480464 bisphenol F results in increased expression of CASP12 mRNA CTD PMID:30951980 bortezomib increases cleavage ISO RGD:731442 6480464 Bortezomib results in increased cleavage of CASP12 protein CTD PMID:15509775 , PMID:16357177 brefeldin A increases activity ISO RGD:731442 6480464 Brefeldin A results in increased activity of CASP12 protein CTD PMID:20493918 brefeldin A multiple interactions ISO RGD:731442 6480464 Apigenin inhibits the reaction [Brefeldin A results in increased activity of CASP12 protein] CTD PMID:20493918 C.I. Natural Red 20 multiple interactions EXP 6480464 [Enzyme Activators results in increased activity of EIF2AK3 protein] inhibits the reaction [shikonin inhibits the reaction [Glutamic Acid results in increased cleavage of CASP12 protein]], shikonin inhibits the reaction [Glutamic Acid results in increased expression of and results in increased cleavage of CASP12 protein] CTD PMID:35028790 cadmium atom multiple interactions ISO RGD:1348077 6480464 1 more ... CTD PMID:19442655 cadmium atom increases activity ISO RGD:731442 6480464 Cadmium results in increased activity of CASP12 protein CTD PMID:20600546 cadmium dichloride increases activity ISO RGD:731442 6480464 Cadmium Chloride results in increased activity of CASP12 protein CTD PMID:17588656 cadmium dichloride increases cleavage EXP 6480464 Cadmium Chloride results in increased cleavage of CASP12 protein CTD PMID:31433112 cadmium dichloride multiple interactions EXP 6480464 DDIT3 protein promotes the reaction [Cadmium Chloride results in decreased expression of CASP12 protein], Resveratrol inhibits the reaction [Cadmium Chloride results in increased cleavage of CASP12 protein] CTD PMID:31348969 , PMID:31433112 cadmium dichloride decreases expression EXP 6480464 Cadmium Chloride results in decreased expression of CASP12 protein CTD PMID:31348969 cadmium dichloride increases expression ISO RGD:731442 6480464 Cadmium Chloride results in increased expression of CASP12 mRNA CTD PMID:25409916 Chikusetsusaponin-V multiple interactions ISO RGD:1348077 6480464 chikusetsusaponin V inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of CASP12 mRNA] CTD PMID:25073091 chloroacetic acid multiple interactions ISO RGD:731442 6480464 Acetylcysteine inhibits the reaction [chloroacetic acid results in increased cleavage of and results in increased activity of CASP12 protein] more ... CTD PMID:25451595 chlorogenic acid multiple interactions EXP 6480464 Chlorogenic Acid inhibits the reaction [Glucose results in increased expression of CASP12 protein] CTD PMID:34801538 chlorohydrocarbon multiple interactions EXP 6480464 [Hydrocarbons, Chlorinated co-treated with Polychlorinated Biphenyls co-treated with methylmercuric chloride] results in increased expression of CASP12 mRNA CTD PMID:30744511 chloroquine multiple interactions EXP 6480464 Chloroquine promotes the reaction [cadmium acetate results in increased expression of CASP12 protein] CTD PMID:29870746 chlorpyrifos affects expression EXP 6480464 Chlorpyrifos affects the expression of CASP12 mRNA CTD PMID:17452286 choline multiple interactions ISO RGD:731442 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CASP12 mRNA CTD PMID:20938992 chromium(6+) multiple interactions EXP 6480464 [Potassium Dichromate results in increased abundance of chromium hexavalent ion] which results in increased cleavage of CASP12 protein CTD PMID:30974164 cimetidine multiple interactions ISO RGD:731442 6480464 Cimetidine inhibits the reaction [Ethanol results in increased expression of CASP12 protein] CTD PMID:27983966 cisplatin multiple interactions ISO RGD:1348077 6480464 [vorinostat co-treated with Cisplatin] results in increased activity of CASP12 protein CTD PMID:19280190 cisplatin increases expression EXP 6480464 Cisplatin results in increased expression of CASP12 mRNA, Cisplatin results in increased expression of CASP12 protein CTD PMID:23603837 , PMID:33631298 cisplatin increases cleavage EXP 6480464 Cisplatin results in increased cleavage of CASP12 protein CTD PMID:33631298 cisplatin multiple interactions EXP 6480464 Cisplatin results in increased cleavage of and results in increased activity of CASP12 protein more ... CTD PMID:17567590 more ... cisplatin affects cleavage EXP 6480464 Cisplatin affects the cleavage of CASP12 protein CTD PMID:20071420 cisplatin increases cleavage ISO RGD:731442 6480464 Cisplatin results in increased cleavage of CASP12 protein CTD PMID:16357177 , PMID:21616140 cisplatin multiple interactions ISO RGD:731442 6480464 [Cisplatin co-treated with RELB mutant form co-treated with TNF protein] results in decreased expression of CASP12 mRNA more ... CTD PMID:21616140 , PMID:23625948 citric acid multiple interactions ISO RGD:1348077 6480464 [Citric Acid co-treated with zinc chloride] results in increased activity of CASP12 protein CTD PMID:16624386 clofibric acid multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CASP12 mRNA CTD PMID:17602206 cobalt dichloride decreases expression EXP 6480464 cobaltous chloride results in decreased expression of CASP12 mRNA CTD PMID:24386269 corticosterone decreases expression EXP 6480464 Corticosterone results in decreased expression of CASP12 mRNA CTD PMID:15755911 Cuprizon increases expression EXP 6480464 Cuprizone results in increased expression of CASP12 mRNA CTD PMID:25704630 more ... curcumin increases expression ISO RGD:731442 6480464 Curcumin results in increased expression of CASP12 protein CTD PMID:21793155 curcumin multiple interactions EXP 6480464 Curcumin inhibits the reaction [Streptozocin results in increased cleavage of CASP12 protein] CTD PMID:25541178 D-glucose increases cleavage ISO RGD:731442 6480464 Glucose results in increased cleavage of CASP12 protein CTD PMID:30076216 D-glucose multiple interactions EXP 6480464 Chlorogenic Acid inhibits the reaction [Glucose results in increased expression of CASP12 protein] CTD PMID:34801538 D-glucose increases expression EXP 6480464 Glucose results in increased expression of CASP12 protein CTD PMID:34801538 D-glucose multiple interactions ISO RGD:731442 6480464 TRPM7 protein affects the reaction [Glucose results in increased cleavage of CASP12 protein], waixenicin A inhibits the reaction [Glucose results in increased cleavage of CASP12 protein] CTD PMID:30076216 DDE increases expression EXP 6480464 Dichlorodiphenyl Dichloroethylene results in increased expression of CASP12 mRNA CTD PMID:21384494 demethoxycurcumin multiple interactions ISO RGD:1348077 6480464 demethoxycurcumin analog inhibits the reaction [Thapsigargin results in increased expression of CASP12 protein modified form] CTD PMID:26264395 desferrioxamine B multiple interactions ISO RGD:1348077 6480464 Deferoxamine promotes the reaction [manganese chloride results in increased cleavage of and results in increased activity of CASP12 protein] CTD PMID:23764342 Diacetoxyscirpenol decreases expression ISO RGD:731442 6480464 diacetoxyscirpenol results in decreased expression of CASP12 mRNA CTD PMID:31836554 diarsenic trioxide increases expression EXP 6480464 Arsenic Trioxide results in increased expression of CASP12 mRNA, Arsenic Trioxide results in increased expression of CASP12 protein modified form CTD PMID:19730151 , PMID:23664956 diarsenic trioxide multiple interactions ISO RGD:731442 6480464 2-aminoethoxydiphenyl borate inhibits the reaction [Arsenic Trioxide results in increased cleavage of CASP12 protein] more ... CTD PMID:24157283 more ... diarsenic trioxide increases expression ISO RGD:731442 6480464 Arsenic Trioxide results in increased expression of CASP12 protein modified form CTD PMID:23664956 , PMID:27638049 diarsenic trioxide multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased cleavage of CASP12 protein] CTD PMID:21145380 diarsenic trioxide increases degradation ISO RGD:731442 6480464 Arsenic Trioxide results in increased degradation of CASP12 protein CTD PMID:24157283 diarsenic trioxide increases expression ISO RGD:1348077 6480464 Arsenic Trioxide results in increased expression of CASP12 mRNA CTD PMID:22959511 diarsenic trioxide increases cleavage ISO RGD:731442 6480464 Arsenic Trioxide results in increased cleavage of CASP12 protein CTD PMID:27461142 diarsenic trioxide increases cleavage EXP 6480464 Arsenic Trioxide results in increased cleavage of CASP12 protein CTD PMID:21145380 diarsenic trioxide increases cleavage ISO RGD:1348077 6480464 Arsenic Trioxide results in increased cleavage of CASP12 protein CTD PMID:19695276 , PMID:26110921 diarsenic trioxide multiple interactions ISO RGD:1348077 6480464 Arsenic Trioxide promotes the reaction [tetraarsenic tetrasulfide results in increased cleavage of CASP12 protein] more ... CTD PMID:22959511 more ... diazinon affects expression EXP 6480464 Diazinon affects the expression of CASP12 mRNA CTD PMID:17452286 dibutyl phthalate multiple interactions ISO RGD:731442 6480464 Melatonin inhibits the reaction [Dibutyl Phthalate results in increased activity of CASP12 protein] CTD PMID:30910607 dieldrin affects expression EXP 6480464 Dieldrin affects the expression of CASP12 mRNA CTD PMID:22546817 diethylstilbestrol increases activity EXP 6480464 Diethylstilbestrol results in increased activity of CASP12 protein CTD PMID:20932895 dimethylarsinic acid increases expression ISO RGD:731442 6480464 Cacodylic Acid results in increased expression of CASP12 mRNA, Cacodylic Acid results in increased expression of CASP12 protein CTD PMID:22246474 dioxygen increases cleavage ISO RGD:731442 6480464 Oxygen deficiency results in increased cleavage of CASP12 protein CTD PMID:24680926 disodium selenite decreases expression ISO RGD:1348077 6480464 Sodium Selenite results in decreased expression of CASP12 protein CTD PMID:34520753 doxorubicin multiple interactions EXP 6480464 Doxorubicin results in increased cleavage of and results in increased activity of CASP12 protein, pifithrin inhibits the reaction [Doxorubicin results in increased cleavage of and results in increased activity of CASP12 protein] CTD PMID:15556633 , PMID:16687611 doxorubicin increases expression ISO RGD:731442 6480464 Doxorubicin results in increased expression of CASP12 mRNA CTD PMID:26873546 doxorubicin multiple interactions ISO RGD:731442 6480464 [Doxorubicin co-treated with Dexrazoxane] results in decreased expression of CASP12 mRNA CTD PMID:26873546 doxorubicin increases activity ISO RGD:731442 6480464 Doxorubicin results in increased activity of CASP12 protein CTD PMID:20656019 edaravone multiple interactions EXP 6480464 Edaravone inhibits the reaction [[Pilocarpine co-treated with Lithium] results in increased expression of CASP12 protein] CTD PMID:21429313 elemental selenium multiple interactions EXP 6480464 Selenium inhibits the reaction [nickel sulfate results in increased expression of CASP12 protein] CTD PMID:34612572 emodin decreases expression ISO RGD:731442 6480464 Emodin results in decreased expression of CASP12 mRNA CTD PMID:21319176 endosulfan decreases expression EXP 6480464 Endosulfan results in decreased expression of CASP12 mRNA CTD PMID:29391264 endosulfan affects expression EXP 6480464 Endosulfan affects the expression of CASP12 mRNA CTD PMID:31464424 epoxiconazole increases expression ISO RGD:731442 6480464 epoxiconazole results in increased expression of CASP12 mRNA CTD PMID:35436446 ethanol increases cleavage ISO RGD:731442 6480464 Ethanol results in increased cleavage of CASP12 protein CTD PMID:28119953 ethanol increases expression ISO RGD:731442 6480464 Ethanol results in increased expression of CASP12 protein CTD PMID:27983966 ethanol multiple interactions ISO RGD:731442 6480464 Cimetidine inhibits the reaction [Ethanol results in increased expression of CASP12 protein] more ... CTD PMID:27983966 , PMID:28119953 ethanol increases expression ISO RGD:1348077 6480464 Ethanol results in increased expression of CASP12 protein modified form CTD PMID:24224909 ethanol increases activity ISO RGD:1348077 6480464 Ethanol results in increased activity of CASP12 protein CTD PMID:24224909 ethanol multiple interactions ISO RGD:1348077 6480464 Resveratrol inhibits the reaction [Ethanol results in increased activity of CASP12 protein], Resveratrol inhibits the reaction [Ethanol results in increased expression of CASP12 protein modified form] CTD PMID:24224909 ethylene glycol bis(2-aminoethyl)tetraacetic acid multiple interactions ISO RGD:731442 6480464 Egtazic Acid inhibits the reaction [Paraoxon results in increased expression of CASP12 protein] CTD PMID:20079824 excitatory amino acid agonist multiple interactions ISO RGD:731442 6480464 Excitatory Amino Acid Agonists results in increased expression of and results in increased cleavage of CASP12 protein, Plant Extracts inhibits the reaction [Excitatory Amino Acid Agonists results in increased expression of and results in increased cleavage of CASP12 protein] CTD PMID:28315776 fisetin increases expression ISO RGD:1348077 6480464 fisetin results in increased expression of CASP12 protein CTD PMID:28181380 fisetin multiple interactions ISO RGD:1348077 6480464 1 more ... CTD PMID:28181380 flutamide decreases expression EXP 6480464 Flutamide results in decreased expression of CASP12 mRNA CTD PMID:24793618 folic acid multiple interactions ISO RGD:731442 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CASP12 mRNA, Folic Acid inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form co-treated with MAPT protein mutant form] results in increased expression of CASP12 protein modified form] CTD PMID:20938992 , PMID:29068127 furan increases expression EXP 6480464 furan results in increased expression of CASP12 mRNA CTD PMID:22079235 furan multiple interactions ISO RGD:731442 6480464 rhodioloside inhibits the reaction [furan results in increased cleavage of CASP12 protein] CTD PMID:34450210 furan increases cleavage ISO RGD:731442 6480464 furan results in increased cleavage of CASP12 protein CTD PMID:34450210 furosemide affects expression EXP 6480464 Furosemide affects the expression of CASP12 mRNA CTD PMID:17497460 galactose increases expression EXP 6480464 Galactose results in increased expression of CASP12 protein CTD PMID:34673010 galactose multiple interactions EXP 6480464 agomelatine inhibits the reaction [Galactose results in increased expression of CASP12 protein], Melatonin inhibits the reaction [Galactose results in increased expression of CASP12 protein] CTD PMID:34673010 geneticin increases cleavage ISO RGD:1348077 6480464 antibiotic G 418 results in increased cleavage of CASP12 protein CTD PMID:15241557 gentamycin multiple interactions EXP 6480464 Gentamicins results in increased cleavage of and results in increased activity of CASP12 protein CTD PMID:17567590 gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of CASP12 mRNA CTD PMID:33387578 glucose multiple interactions ISO RGD:731442 6480464 TRPM7 protein affects the reaction [Glucose results in increased cleavage of CASP12 protein], waixenicin A inhibits the reaction [Glucose results in increased cleavage of CASP12 protein] CTD PMID:30076216 glucose multiple interactions EXP 6480464 Chlorogenic Acid inhibits the reaction [Glucose results in increased expression of CASP12 protein] CTD PMID:34801538 glucose increases expression EXP 6480464 Glucose results in increased expression of CASP12 protein CTD PMID:34801538 glucose increases cleavage ISO RGD:731442 6480464 Glucose results in increased cleavage of CASP12 protein CTD PMID:30076216 GW 4064 decreases expression ISO RGD:731442 6480464 GW 4064 results in decreased expression of CASP12 mRNA CTD PMID:26655953 heparin multiple interactions ISO RGD:731442 6480464 Heparin inhibits the reaction [Paraoxon results in increased expression of CASP12 protein] CTD PMID:20079824 hydralazine multiple interactions ISO RGD:731442 6480464 Hydralazine inhibits the reaction [Ethanol results in increased cleavage of CASP12 protein] CTD PMID:28119953 hydrogen peroxide increases expression EXP 6480464 Hydrogen Peroxide results in increased expression of CASP12 protein modified form CTD PMID:22081883 hydrogen peroxide increases cleavage ISO RGD:731442 6480464 Hydrogen Peroxide results in increased cleavage of CASP12 protein CTD PMID:20878536 hydrogen peroxide increases activity EXP 6480464 Hydrogen Peroxide results in increased activity of CASP12 protein CTD PMID:25065601 hydrogen peroxide multiple interactions EXP 6480464 calycopterin results in decreased susceptibility to [Hydrogen Peroxide results in increased expression of CASP12 protein modified form], PBK protein inhibits the reaction [Hydrogen Peroxide results in increased activity of CASP12 protein] CTD PMID:22081883 , PMID:25065601 hydroxamic acid multiple interactions EXP 6480464 Hydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP12 protein modified form] CTD PMID:30503585 icosanoid multiple interactions EXP 6480464 Eicosanoids analog inhibits the reaction [Cisplatin results in increased expression of CASP12 mRNA], Eicosanoids analog inhibits the reaction [Cisplatin results in increased expression of CASP12 protein] CTD PMID:23603837 iron(III) nitrilotriacetate increases expression EXP 6480464 ferric nitrilotriacetate results in increased expression of CASP12 mRNA CTD PMID:23208426 isoflurane decreases expression EXP 6480464 Isoflurane results in decreased expression of CASP12 mRNA CTD PMID:16978161 ketoconazole increases expression ISO RGD:731442 6480464 Ketoconazole results in increased expression of CASP12 mRNA CTD PMID:25808816 KN-93 multiple interactions EXP 6480464 KN 93 inhibits the reaction [cadmium acetate results in increased cleavage of CASP12 protein] CTD PMID:29883672 L-glutamic acid multiple interactions EXP 6480464 [Enzyme Activators results in increased activity of EIF2AK3 protein] inhibits the reaction [shikonin inhibits the reaction [Glutamic Acid results in increased cleavage of CASP12 protein]] more ... CTD PMID:35028790 L-methionine multiple interactions ISO RGD:731442 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CASP12 mRNA CTD PMID:20938992 lead(0) increases expression EXP 6480464 Lead results in increased expression of CASP12 mRNA CTD PMID:24791885 lead(2+) increases expression EXP 6480464 Lead results in increased expression of CASP12 mRNA CTD PMID:24791885 lipopolysaccharide increases expression ISO RGD:731442 6480464 Lipopolysaccharides results in increased expression of CASP12 protein CTD PMID:28245985 lipopolysaccharide multiple interactions ISO RGD:1348077 6480464 4-phenylbutyric acid inhibits the reaction [Lipopolysaccharides results in increased expression of CASP12 protein] CTD PMID:28245985 lipopolysaccharide multiple interactions ISO RGD:731442 6480464 4-phenylbutyric acid inhibits the reaction [Lipopolysaccharides results in increased expression of CASP12 protein] CTD PMID:28245985 lipopolysaccharide increases expression ISO RGD:1348077 6480464 Lipopolysaccharides results in increased expression of CASP12 protein CTD PMID:28245985 lithium atom multiple interactions EXP 6480464 [Pilocarpine co-treated with Lithium] results in increased expression of CASP12 mRNA more ... CTD PMID:21429313 lithium hydride multiple interactions EXP 6480464 [Pilocarpine co-treated with Lithium] results in increased expression of CASP12 mRNA more ... CTD PMID:21429313 manganese(II) chloride increases cleavage ISO RGD:731442 6480464 manganese chloride results in increased cleavage of CASP12 protein CTD PMID:26064043 manganese(II) chloride multiple interactions EXP 6480464 SNCA protein promotes the reaction [manganese chloride results in increased expression of CASP12 protein] CTD PMID:23934647 manganese(II) chloride increases cleavage EXP 6480464 manganese chloride results in increased cleavage of CASP12 protein CTD PMID:25732873 manganese(II) chloride increases expression EXP 6480464 manganese chloride results in increased expression of CASP12 mRNA, manganese chloride results in increased expression of CASP12 protein CTD PMID:23934647 more ... manganese(II) chloride multiple interactions ISO RGD:1348077 6480464 Deferoxamine promotes the reaction [manganese chloride results in increased cleavage of and results in increased activity of CASP12 protein], manganese chloride results in increased cleavage of and results in increased activity of CASP12 protein CTD PMID:23764342 manganese(II) chloride multiple interactions ISO RGD:731442 6480464 Plant Extracts inhibits the reaction [manganese chloride results in increased cleavage of CASP12 protein] CTD PMID:26064043 meglumine amidotrizoate increases cleavage EXP 6480464 Diatrizoate Meglumine results in increased cleavage of CASP12 protein CTD PMID:20071420 melatonin multiple interactions EXP 6480464 [Melatonin co-treated with Aluminum Chloride] results in decreased expression of CASP12 protein more ... CTD PMID:17645694 more ... melatonin multiple interactions ISO RGD:731442 6480464 Melatonin inhibits the reaction [Dibutyl Phthalate results in increased activity of CASP12 protein] CTD PMID:30910607 methamphetamine increases cleavage EXP 6480464 Methamphetamine results in increased cleavage of CASP12 protein CTD PMID:28070110 methamphetamine decreases expression ISO RGD:731442 6480464 Methamphetamine results in decreased expression of CASP12 protein CTD PMID:32203791 methamphetamine multiple interactions ISO RGD:1348077 6480464 CDK5 protein affects the reaction [Methamphetamine results in increased expression of CASP12 protein], TXN protein inhibits the reaction [Methamphetamine results in decreased expression of CASP12 protein] CTD PMID:29705343 , PMID:32203791 methamphetamine multiple interactions EXP 6480464 CDK5 protein affects the reaction [Methamphetamine results in increased expression of CASP12 protein], Melatonin inhibits the reaction [Methamphetamine results in increased cleavage of CASP12 protein] CTD PMID:28070110 , PMID:29705343 methamphetamine increases expression EXP 6480464 Methamphetamine results in increased expression of CASP12 mRNA, Methamphetamine results in increased expression of CASP12 protein CTD PMID:28619521 , PMID:29705343 methamphetamine increases expression ISO RGD:1348077 6480464 Methamphetamine results in increased expression of CASP12 protein CTD PMID:29705343 methapyrilene increases expression EXP 6480464 Methapyrilene results in increased expression of CASP12 mRNA CTD PMID:17450226 methylmercury chloride decreases expression ISO RGD:731442 6480464 methylmercuric chloride results in decreased expression of CASP12 protein CTD PMID:31330229 methylmercury chloride multiple interactions EXP 6480464 [Hydrocarbons, Chlorinated co-treated with Polychlorinated Biphenyls co-treated with methylmercuric chloride] results in increased expression of CASP12 mRNA CTD PMID:30744511 methylmercury chloride multiple interactions ISO RGD:731442 6480464 Acetylcysteine inhibits the reaction [methylmercuric chloride results in decreased expression of CASP12 protein] more ... CTD PMID:31330229 methylseleninic acid multiple interactions ISO RGD:1348077 6480464 HSPA5 protein inhibits the reaction [methylselenic acid results in increased cleavage of CASP12 protein] CTD PMID:16204082 methylseleninic acid increases cleavage ISO RGD:1348077 6480464 methylselenic acid results in increased cleavage of CASP12 protein CTD PMID:16204082 minocycline multiple interactions EXP 6480464 Minocycline inhibits the reaction [APP protein alternative form results in increased activity of CASP12 protein], Minocycline results in decreased degradation of [Paraquat results in increased expression of CASP12 protein] CTD PMID:17406652 , PMID:22245251 minocycline decreases expression EXP 6480464 Minocycline results in decreased expression of CASP12 mRNA, Minocycline results in decreased expression of CASP12 protein CTD PMID:14998631 Mitotane increases expression EXP 6480464 Mitotane analog results in increased expression of CASP12 mRNA, Mitotane results in increased expression of CASP12 mRNA CTD PMID:23485034 N-acetyl-L-cysteine multiple interactions ISO RGD:731442 6480464 Acetylcysteine inhibits the reaction [chloroacetic acid results in increased cleavage of and results in increased activity of CASP12 protein] more ... CTD PMID:21616140 more ... N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [arsenic trioxide results in increased cleavage of CASP12 protein] more ... CTD PMID:18077580 more ... N-methyl-4-phenylpyridinium increases expression ISO RGD:1348077 6480464 1-Methyl-4-phenylpyridinium results in increased expression of CASP12 mRNA CTD PMID:25073091 N-methyl-4-phenylpyridinium increases methylation EXP 6480464 1-Methyl-4-phenylpyridinium results in increased methylation of CASP12 gene CTD PMID:28801915 N-methyl-4-phenylpyridinium increases expression EXP 6480464 1-Methyl-4-phenylpyridinium results in increased expression of CASP12 mRNA CTD PMID:28801915 N-methyl-4-phenylpyridinium increases cleavage EXP 6480464 1-Methyl-4-phenylpyridinium results in increased cleavage of CASP12 protein CTD PMID:24140863 N-methyl-4-phenylpyridinium multiple interactions EXP 6480464 pyrazolanthrone inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased cleavage of CASP12 protein], TXN protein affects the reaction [1-Methyl-4-phenylpyridinium results in increased cleavage of CASP12 protein] CTD PMID:24140863 N-methyl-4-phenylpyridinium multiple interactions ISO RGD:1348077 6480464 chikusetsusaponin V inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of CASP12 mRNA], TXN protein inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased cleavage of CASP12 protein] CTD PMID:24140863 , PMID:25073091 N-nitrosodiethylamine multiple interactions EXP 6480464 [3 more ... CTD PMID:17602206 more ... N-nitrosodiethylamine multiple interactions ISO RGD:731442 6480464 [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CASP12 mRNA CTD PMID:24535843 N-nitrosodiethylamine increases expression ISO RGD:731442 6480464 Diethylnitrosamine results in increased expression of CASP12 mRNA CTD PMID:24535843 N-nitrosodimethylamine increases expression EXP 6480464 Dimethylnitrosamine results in increased expression of CASP12 mRNA CTD PMID:25380136 nickel sulfate increases expression EXP 6480464 nickel sulfate results in increased expression of CASP12 mRNA, nickel sulfate results in increased expression of CASP12 protein CTD PMID:28296042 , PMID:34612572 nickel sulfate multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of CASP12 mRNA] more ... CTD PMID:28296042 , PMID:34612572 nicotine multiple interactions ISO RGD:731442 6480464 [Nicotine co-treated with 1-Methyl-4-phenyl-1 more ... CTD PMID:20230807 nicotine multiple interactions EXP 6480464 Nicotine inhibits the reaction [Tunicamycin results in increased activity of CASP12 protein] CTD PMID:18477628 ochratoxin A increases expression EXP 6480464 ochratoxin A results in increased expression of CASP12 mRNA CTD PMID:23208426 oxidopamine increases cleavage EXP 6480464 Oxidopamine results in increased cleavage of CASP12 protein CTD PMID:34302886 oxidopamine multiple interactions EXP 6480464 Resveratrol inhibits the reaction [Oxidopamine results in increased cleavage of CASP12 protein] CTD PMID:34302886 paclitaxel increases expression ISO RGD:1348077 6480464 Paclitaxel results in increased expression of CASP12 protein CTD PMID:18098270 paclitaxel multiple interactions ISO RGD:1348077 6480464 [Tretinoin co-treated with Paclitaxel] results in increased expression of CASP12 protein CTD PMID:17701358 paclitaxel decreases expression ISO RGD:1348077 6480464 Paclitaxel results in decreased expression of CASP12 protein CTD PMID:17701358 paracetamol increases cleavage ISO RGD:731442 6480464 Acetaminophen results in increased cleavage of CASP12 protein CTD PMID:14747384 paracetamol multiple interactions ISO RGD:731442 6480464 O(2)-vinyl-1-(pyrrolidin-1-yl)diazen-1-ium-1, 2-diolate inhibits the reaction [Acetaminophen results in increased expression of CASP12 mRNA] CTD PMID:12540782 paracetamol increases expression ISO RGD:731442 6480464 Acetaminophen results in increased expression of CASP12 mRNA CTD PMID:12540782 paraoxon multiple interactions ISO RGD:731442 6480464 Egtazic Acid inhibits the reaction [Paraoxon results in increased expression of CASP12 protein] more ... CTD PMID:20079824 paraoxon increases expression ISO RGD:731442 6480464 Paraoxon results in increased expression of CASP12 protein CTD PMID:20079824 paraquat multiple interactions EXP 6480464 Minocycline results in decreased degradation of [Paraquat results in increased expression of CASP12 protein], NFE2L2 mutant form inhibits the reaction [Paraquat results in increased expression of CASP12 mRNA] CTD PMID:22245251 , PMID:22678742 paraquat increases activity EXP 6480464 Paraquat results in increased activity of CASP12 protein CTD PMID:24912633 paraquat increases expression EXP 6480464 Paraquat results in increased expression of CASP12 mRNA, Paraquat results in increased expression of CASP12 protein CTD PMID:22678742 paraquat increases degradation EXP 6480464 Paraquat results in increased degradation of CASP12 protein CTD PMID:22245251 perfluorooctane-1-sulfonic acid multiple interactions ISO RGD:731442 6480464 [perfluorooctane sulfonic acid co-treated with Pectins] results in increased expression of CASP12 mRNA CTD PMID:36331819 perfluorooctanoic acid increases expression EXP 6480464 perfluorooctanoic acid results in increased expression of CASP12 mRNA CTD PMID:16221955 phenobarbital multiple interactions ISO RGD:731442 6480464 [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CASP12 mRNA, NR1I3 protein affects the reaction [Phenobarbital results in increased expression of CASP12 mRNA] CTD PMID:19482888 , PMID:24535843 phenobarbital multiple interactions EXP 6480464 [3 more ... CTD PMID:27048571 phenobarbital increases expression ISO RGD:731442 6480464 Phenobarbital results in increased expression of CASP12 mRNA CTD PMID:19482888 phorbol 13-acetate 12-myristate multiple interactions ISO RGD:1348077 6480464 Tetradecanoylphorbol Acetate inhibits the reaction [Trichlorfon results in increased cleavage of and results in increased activity of CASP12 protein] CTD PMID:19631781 poly(guanylic acid) multiple interactions EXP 6480464 Poly G inhibits the reaction [Silicon Dioxide results in increased expression of CASP12 protein] CTD PMID:31028789 potassium dichromate multiple interactions EXP 6480464 [Potassium Dichromate results in increased abundance of chromium hexavalent ion] which results in increased cleavage of CASP12 protein CTD PMID:30974164 procaine multiple interactions ISO RGD:731442 6480464 Procaine inhibits the reaction [Paraoxon results in increased expression of CASP12 protein] CTD PMID:20079824 procymidone increases expression ISO RGD:731442 6480464 procymidone results in increased expression of CASP12 CTD PMID:33413771 quartz increases expression ISO RGD:1348077 6480464 Quartz results in increased expression of CASP12 protein CTD PMID:29729927 quercetin multiple interactions ISO RGD:1348077 6480464 [temozolomide co-treated with Quercetin] results in increased expression of CASP12 protein CTD PMID:24126416 resveratrol multiple interactions ISO RGD:1348077 6480464 CASP12 mutant form inhibits the reaction [Resveratrol results in increased cleavage of PARP1 protein] more ... CTD PMID:24224909 , PMID:24264887 resveratrol multiple interactions EXP 6480464 Resveratrol inhibits the reaction [Cadmium Chloride results in increased cleavage of CASP12 protein], Resveratrol inhibits the reaction [Oxidopamine results in increased cleavage of CASP12 protein] CTD PMID:31433112 , PMID:34302886 resveratrol affects expression EXP 6480464 resveratrol affects the expression of CASP12 mRNA CTD PMID:17959022 resveratrol increases expression ISO RGD:1348077 6480464 resveratrol results in increased expression of CASP12 protein CTD PMID:24264887 rimonabant multiple interactions ISO RGD:731442 6480464 Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CASP12 mRNA] CTD PMID:19030233 rotenone multiple interactions ISO RGD:731442 6480464 4-phenylbutyric acid inhibits the reaction [Rotenone results in increased activity of CASP12 protein], salubrinal inhibits the reaction [Rotenone results in increased expression of CASP12 mRNA] CTD PMID:17459145 , PMID:25428620 rotenone multiple interactions EXP 6480464 7-methyl-5-(1-((3-(trifluoromethyl)phenyl)acetyl)-2 more ... CTD PMID:26446018 , PMID:33137417 rotenone increases cleavage EXP 6480464 Rotenone results in increased cleavage of CASP12 protein CTD PMID:26446018 rotenone increases expression ISO RGD:731442 6480464 Rotenone results in increased expression of CASP12 mRNA CTD PMID:25428620 rotenone increases expression EXP 6480464 Rotenone results in increased expression of CASP12 protein modified form CTD PMID:33137417 rotenone increases activity ISO RGD:731442 6480464 Rotenone results in increased activity of CASP12 protein CTD PMID:17459145 rubimaillin multiple interactions ISO RGD:1348077 6480464 BCL2L1 protein inhibits the reaction [rubimaillin results in increased activity of CASP12 protein] CTD PMID:19716835 rubimaillin increases activity ISO RGD:1348077 6480464 rubimaillin results in increased activity of CASP12 protein CTD PMID:19716835 ruthenium red multiple interactions ISO RGD:1348077 6480464 [Verapamil co-treated with Ruthenium Red co-treated with 2-aminoethoxydiphenyl borate] inhibits the reaction [Trichlorfon results in increased cleavage of and results in increased activity of CASP12 protein] CTD PMID:19631781 S-adenosyl-L-methioninate decreases expression ISO RGD:731442 6480464 S-Adenosylmethionine results in decreased expression of CASP12 mRNA CTD PMID:18098314 S-adenosyl-L-methionine decreases expression ISO RGD:731442 6480464 S-Adenosylmethionine results in decreased expression of CASP12 mRNA CTD PMID:18098314 Salidroside multiple interactions ISO RGD:731442 6480464 rhodioloside inhibits the reaction [furan results in increased cleavage of CASP12 protein] CTD PMID:34450210 salubrinal multiple interactions ISO RGD:731442 6480464 Acetylcysteine inhibits the reaction [salubrinal promotes the reaction [Cisplatin results in increased cleavage of CASP12 protein]] more ... CTD PMID:21616140 more ... salubrinal multiple interactions ISO RGD:1348077 6480464 salubrinal inhibits the reaction [T-2 Toxin results in increased expression of CASP12 mRNA], salubrinal inhibits the reaction [T-2 Toxin results in increased expression of CASP12 protein] CTD PMID:34673134 salubrinal multiple interactions EXP 6480464 salubrinal inhibits the reaction [arsenite results in increased activity of CASP12 protein], salubrinal inhibits the reaction [Rotenone results in increased cleavage of CASP12 protein] CTD PMID:18226606 , PMID:26446018 selenium atom multiple interactions EXP 6480464 Selenium inhibits the reaction [nickel sulfate results in increased expression of CASP12 protein] CTD PMID:34612572 senecionine increases expression EXP 6480464 senecionine results in increased expression of CASP12 mRNA CTD PMID:32419051 Shikonin multiple interactions EXP 6480464 [Enzyme Activators results in increased activity of EIF2AK3 protein] inhibits the reaction [shikonin inhibits the reaction [Glutamic Acid results in increased cleavage of CASP12 protein]], shikonin inhibits the reaction [Glutamic Acid results in increased expression of and results in increased cleavage of CASP12 protein] CTD PMID:35028790 silicon dioxide increases expression EXP 6480464 Silicon Dioxide results in increased expression of CASP12 protein CTD PMID:31028789 silicon dioxide multiple interactions EXP 6480464 Poly G inhibits the reaction [Silicon Dioxide results in increased expression of CASP12 protein] CTD PMID:31028789 simvastatin multiple interactions ISO RGD:1348077 6480464 Simvastatin results in increased cleavage of and results in increased activity of CASP12 protein CTD PMID:19253821 sirolimus decreases cleavage ISO RGD:731442 6480464 Sirolimus results in decreased cleavage of CASP12 protein CTD PMID:20511674 sirolimus multiple interactions EXP 6480464 Sirolimus inhibits the reaction [cadmium acetate results in increased expression of CASP12 protein] CTD PMID:29870746 sodium arsenite multiple interactions EXP 6480464 Melatonin inhibits the reaction [sodium arsenite results in decreased expression of CASP12 protein], Melatonin inhibits the reaction [sodium arsenite results in increased activity of CASP12 protein] CTD PMID:17645694 , PMID:18715270 sodium arsenite multiple interactions ISO RGD:1348077 6480464 HSPA5 protein affects the reaction [sodium arsenite results in increased cleavage of CASP12 protein] CTD PMID:33241020 sodium arsenite increases cleavage ISO RGD:1348077 6480464 sodium arsenite results in increased cleavage of CASP12 protein CTD PMID:33241020 sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of CASP12 protein CTD PMID:17645694 , PMID:17681577 sodium arsenite increases activity EXP 6480464 sodium arsenite results in increased activity of CASP12 protein CTD PMID:18715270 sodium fluoride increases expression ISO RGD:731442 6480464 Sodium Fluoride results in increased expression of CASP12 mRNA CTD PMID:30225638 streptozocin multiple interactions ISO RGD:731442 6480464 FGF21 protein affects the reaction [Streptozocin results in increased expression of CASP12 protein modified form], sulforaphane inhibits the reaction [Streptozocin results in increased cleavage of CASP12 protein] CTD PMID:23499715 , PMID:24967692 streptozocin multiple interactions EXP 6480464 Curcumin inhibits the reaction [Streptozocin results in increased cleavage of CASP12 protein] CTD PMID:25541178 streptozocin increases cleavage EXP 6480464 Streptozocin results in increased cleavage of CASP12 protein CTD PMID:25541178 streptozocin increases expression ISO RGD:731442 6480464 Streptozocin results in increased expression of CASP12 protein modified form CTD PMID:23499715 streptozocin increases cleavage ISO RGD:731442 6480464 Streptozocin results in increased cleavage of CASP12 protein CTD PMID:24967692 succimer multiple interactions ISO RGD:731442 6480464 [Succimer co-treated with Magnetite Nanoparticles] results in increased expression of CASP12 mRNA CTD PMID:26378955 sulforaphane multiple interactions ISO RGD:731442 6480464 sulforaphane inhibits the reaction [Streptozocin results in increased cleavage of CASP12 protein] CTD PMID:24967692 sulfur dioxide multiple interactions EXP 6480464 Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased cleavage of CASP12 protein] CTD PMID:30503585 T-2 toxin increases expression ISO RGD:731442 6480464 T-2 Toxin results in increased expression of CASP12 mRNA CTD PMID:34673134 T-2 toxin multiple interactions ISO RGD:731442 6480464 salubrinal inhibits the reaction [T-2 Toxin results in increased expression of CASP12 mRNA] CTD PMID:34673134 T-2 toxin increases expression EXP 6480464 T-2 Toxin results in increased expression of CASP12 protein CTD PMID:34673134 T-2 toxin increases expression ISO RGD:1348077 6480464 T-2 Toxin results in increased expression of CASP12 mRNA, T-2 Toxin results in increased expression of CASP12 protein CTD PMID:34673134 T-2 toxin multiple interactions ISO RGD:1348077 6480464 salubrinal inhibits the reaction [T-2 Toxin results in increased expression of CASP12 mRNA], salubrinal inhibits the reaction [T-2 Toxin results in increased expression of CASP12 protein] CTD PMID:34673134 tauroursodeoxycholic acid multiple interactions EXP 6480464 ursodoxicoltaurine inhibits the reaction [Cisplatin results in increased cleavage of CASP12 protein], ursodoxicoltaurine inhibits the reaction [Cisplatin results in increased expression of CASP12 mRNA] CTD PMID:33631298 tauroursodeoxycholic acid multiple interactions ISO RGD:1348077 6480464 ursodoxicoltaurine inhibits the reaction [Thapsigargin results in increased cleavage of CASP12 protein] CTD PMID:12198651 temozolomide multiple interactions ISO RGD:1348077 6480464 [temozolomide co-treated with Quercetin] results in increased expression of CASP12 protein CTD PMID:24126416 temozolomide increases expression ISO RGD:1348077 6480464 temozolomide results in increased expression of CASP12 protein CTD PMID:24126416 TEMPO multiple interactions EXP 6480464 TEMPO inhibits the reaction [nickel sulfate results in increased expression of CASP12 mRNA], TEMPO inhibits the reaction [nickel sulfate results in increased expression of CASP12 protein] CTD PMID:28296042 testosterone multiple interactions EXP 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of CASP12 mRNA CTD PMID:32741896 tetrachloromethane affects expression EXP 6480464 Carbon Tetrachloride affects the expression of CASP12 protein CTD PMID:16092975 tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of CASP12 mRNA CTD PMID:31150632 thapsigargin multiple interactions ISO RGD:1348077 6480464 demethoxycurcumin analog inhibits the reaction [Thapsigargin results in increased expression of CASP12 protein modified form] more ... CTD PMID:12198651 more ... thapsigargin increases expression ISO RGD:731442 6480464 Thapsigargin results in increased expression of CASP12 protein modified form CTD PMID:30841431 thapsigargin increases expression ISO RGD:1348077 6480464 Thapsigargin results in increased expression of CASP12 protein modified form CTD PMID:26264395 thapsigargin increases activity ISO RGD:1348077 6480464 Thapsigargin results in increased activity of CASP12 protein CTD PMID:24224909 thapsigargin increases activity EXP 6480464 Thapsigargin results in increased activity of CASP12 protein CTD PMID:18477628 thapsigargin increases cleavage EXP 6480464 Thapsigargin results in increased cleavage of CASP12 protein alternative form CTD PMID:16338971 thapsigargin increases activity ISO RGD:731442 6480464 Thapsigargin results in increased activity of CASP12 protein CTD PMID:20493918 thapsigargin multiple interactions ISO RGD:731442 6480464 4-(3-3 more ... CTD PMID:20493918 more ... thapsigargin increases cleavage ISO RGD:1348077 6480464 Thapsigargin results in increased cleavage of CASP12 protein CTD PMID:12198651 thioacetamide multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of CASP12 mRNA CTD PMID:23830814 thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of CASP12 mRNA CTD PMID:34492290 thymoquinone decreases expression ISO RGD:1348077 6480464 thymoquinone results in decreased expression of CASP12 protein CTD PMID:29981725 titanium dioxide decreases expression ISO RGD:731442 6480464 titanium dioxide results in decreased expression of CASP12 mRNA CTD PMID:27760801 titanium dioxide increases expression ISO RGD:731442 6480464 titanium dioxide results in increased expression of CASP12 mRNA CTD PMID:32333507 tributylstannane increases expression EXP 6480464 tributyltin results in increased expression of CASP12 protein CTD PMID:26079211 trichlorfon multiple interactions ISO RGD:1348077 6480464 [Verapamil co-treated with Ruthenium Red co-treated with 2-aminoethoxydiphenyl borate] inhibits the reaction [Trichlorfon results in increased cleavage of and results in increased activity of CASP12 protein] more ... CTD PMID:19631781 trichloroethene increases expression EXP 6480464 Trichloroethylene results in increased expression of CASP12 mRNA CTD PMID:33387578 trichostatin A decreases expression EXP 6480464 trichostatin A results in decreased expression of CASP12 mRNA CTD PMID:23558232 Triptolide increases expression ISO RGD:731442 6480464 triptolide results in increased expression of CASP12 protein CTD PMID:26990902 triptonide decreases expression ISO RGD:731442 6480464 triptonide results in decreased expression of CASP12 mRNA CTD PMID:33045310 tunicamycin increases cleavage ISO RGD:731442 6480464 Tunicamycin results in increased cleavage of CASP12 protein CTD PMID:17003819 tunicamycin increases activity ISO RGD:1348077 6480464 Tunicamycin results in increased activity of CASP12 protein CTD PMID:24224909 tunicamycin multiple interactions ISO RGD:1348077 6480464 resveratrol inhibits the reaction [Tunicamycin results in increased activity of CASP12 protein] CTD PMID:24224909 tunicamycin increases activity EXP 6480464 Tunicamycin results in increased activity of CASP12 protein CTD PMID:18477628 tunicamycin multiple interactions EXP 6480464 Nicotine inhibits the reaction [Tunicamycin results in increased activity of CASP12 protein] CTD PMID:18477628 urethane decreases expression ISO RGD:731442 6480464 Urethane results in decreased expression of CASP12 protein CTD PMID:12400877 verapamil multiple interactions ISO RGD:1348077 6480464 [Verapamil co-treated with Ruthenium Red co-treated with 2-aminoethoxydiphenyl borate] inhibits the reaction [Trichlorfon results in increased cleavage of and results in increased activity of CASP12 protein] CTD PMID:19631781 vildagliptin multiple interactions EXP 6480464 Vildagliptin inhibits the reaction [Dietary Fats results in increased cleavage of CASP12 protein] CTD PMID:34081941 vorinostat multiple interactions ISO RGD:1348077 6480464 [vorinostat co-treated with Cisplatin] results in increased activity of CASP12 protein CTD PMID:19280190 zinc atom increases expression EXP 6480464 Zinc deficiency results in increased expression of CASP12 mRNA CTD PMID:19111725 zinc dichloride multiple interactions ISO RGD:1348077 6480464 [Citric Acid co-treated with zinc chloride] results in increased activity of CASP12 protein CTD PMID:16624386 zinc oxide increases expression EXP 6480464 Zinc Oxide results in increased expression of CASP12 mRNA CTD PMID:23232460 zinc oxide increases activity ISO RGD:731442 6480464 Zinc Oxide analog results in increased activity of CASP12 protein CTD PMID:25680694 zinc(0) increases expression EXP 6480464 Zinc deficiency results in increased expression of CASP12 mRNA CTD PMID:19111725
