(-)-epigallocatechin 3-gallate multiple interactions ISO RGD:1342700 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of KIF4A mRNA CTD PMID:22079256 1,1-dichloroethene increases expression ISO RGD:1551183 6480464 vinylidene chloride results in increased expression of KIF4A mRNA CTD PMID:26682919 1,2-dimethylhydrazine increases expression ISO RGD:1551183 6480464 1, 2-Dimethylhydrazine results in increased expression of KIF4 mRNA CTD PMID:22206623 17alpha-ethynylestradiol increases expression ISO RGD:1551183 6480464 Ethinyl Estradiol results in increased expression of KIF4 mRNA CTD PMID:17942748 17alpha-ethynylestradiol affects expression ISO RGD:1551183 6480464 Ethinyl Estradiol affects the expression of KIF4 mRNA CTD PMID:17555576 17alpha-ethynylestradiol multiple interactions ISO RGD:1551183 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of KIF4 mRNA CTD PMID:17942748 17beta-estradiol increases expression ISO RGD:1551183 6480464 Estradiol results in increased expression of KIF4A mRNA CTD PMID:25210133 17beta-estradiol multiple interactions EXP 6480464 [bisphenol A co-treated with Estradiol] results in increased expression of KIF4A mRNA CTD PMID:26496021 17beta-estradiol increases expression ISO RGD:1342700 6480464 Estradiol results in increased expression of KIF4A mRNA CTD PMID:16474171 17beta-estradiol multiple interactions ISO RGD:1551183 6480464 ESR1 protein promotes the reaction [Estradiol results in increased expression of KIF4A mRNA] CTD PMID:25210133 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO RGD:1551183 6480464 [2 more ... CTD PMID:25510870 2,2',4,4'-Tetrabromodiphenyl ether affects expression ISO RGD:1342700 6480464 2 more ... CTD PMID:31173147 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO RGD:1551183 6480464 [2 more ... CTD PMID:25510870 2,3',4,4',5-Pentachlorobiphenyl increases expression ISO RGD:1551183 6480464 2 more ... CTD PMID:31388691 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:1551183 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of KIF4 mRNA CTD PMID:17942748 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of KIF4A mRNA CTD PMID:34747641 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of KIF4A mRNA CTD PMID:32109520 , PMID:33387578 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:1551183 6480464 Tetrachlorodibenzodioxin affects the expression of KIF4 mRNA CTD PMID:21570461 , PMID:26377647 2,3,7,8-tetrachlorodibenzodioxine increases phosphorylation EXP 6480464 Tetrachlorodibenzodioxin results in increased phosphorylation of KIF4A protein CTD PMID:23298284 2-amino-2-deoxy-D-glucopyranose decreases expression EXP 6480464 Glucosamine results in decreased expression of KIF4A mRNA CTD PMID:17109745 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO RGD:1342700 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of KIF4A mRNA CTD PMID:28628672 4-hydroxyphenyl retinamide increases expression ISO RGD:1551183 6480464 Fenretinide results in increased expression of KIF4A mRNA CTD PMID:28973697 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of KIF4A mRNA CTD PMID:24780913 acetohydrazide decreases expression ISO RGD:1551183 6480464 acetylhydrazine results in decreased expression of KIF4 mRNA CTD PMID:15282401 acrylamide decreases expression ISO RGD:1342700 6480464 Acrylamide results in decreased expression of KIF4A mRNA CTD PMID:32763439 aflatoxin B1 affects expression ISO RGD:1342700 6480464 Aflatoxin B1 affects the expression of KIF4A protein CTD PMID:20106945 aldehydo-D-glucosamine decreases expression EXP 6480464 Glucosamine results in decreased expression of KIF4A mRNA CTD PMID:17109745 all-trans-retinoic acid decreases expression ISO RGD:1342700 6480464 Tretinoin results in decreased expression of KIF4A mRNA CTD PMID:33167477 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of KIF4 mRNA CTD PMID:16483693 arsane affects methylation ISO RGD:1342700 6480464 Arsenic affects the methylation of KIF4A gene CTD PMID:25304211 arsenic atom affects methylation ISO RGD:1342700 6480464 Arsenic affects the methylation of KIF4A gene CTD PMID:25304211 arsenite(3-) multiple interactions ISO RGD:1342700 6480464 arsenite inhibits the reaction [G3BP1 protein binds to KIF4A mRNA] CTD PMID:32406909 benzo[a]pyrene decreases expression ISO RGD:1342700 6480464 Benzo(a)pyrene results in decreased expression of KIF4A mRNA CTD PMID:20064835 benzo[a]pyrene affects methylation ISO RGD:1342700 6480464 Benzo(a)pyrene affects the methylation of KIF4A intron CTD PMID:30157460 benzo[a]pyrene increases methylation ISO RGD:1342700 6480464 Benzo(a)pyrene results in increased methylation of KIF4A 5' UTR, Benzo(a)pyrene results in increased methylation of KIF4A promoter CTD PMID:27901495 benzo[a]pyrene increases expression ISO RGD:1551183 6480464 Benzo(a)pyrene results in increased expression of KIF4 mRNA CTD PMID:32417428 benzo[a]pyrene decreases expression ISO RGD:1551183 6480464 Benzo(a)pyrene results in decreased expression of KIF4 mRNA CTD PMID:21569818 benzo[e]pyrene decreases methylation ISO RGD:1342700 6480464 benzo(e)pyrene results in decreased methylation of KIF4A intron CTD PMID:30157460 beta-D-glucosamine decreases expression EXP 6480464 Glucosamine results in decreased expression of KIF4A mRNA CTD PMID:17109745 beta-naphthoflavone multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of KIF4 mRNA CTD PMID:18164116 bis(2-chloroethyl) sulfide decreases expression ISO RGD:1342700 6480464 Mustard Gas results in decreased expression of KIF4A mRNA CTD PMID:25102026 bis(2-ethylhexyl) phthalate decreases expression EXP 6480464 Diethylhexyl Phthalate results in decreased expression of KIF4 mRNA CTD PMID:20920545 bisphenol A increases expression ISO RGD:1342700 6480464 bisphenol A results in increased expression of KIF4A mRNA CTD PMID:16474171 bisphenol A increases methylation ISO RGD:1342700 6480464 bisphenol A results in increased methylation of KIF4A gene CTD PMID:31601247 bisphenol A decreases expression ISO RGD:1342700 6480464 bisphenol A results in decreased expression of KIF4A mRNA CTD PMID:29275510 bisphenol A multiple interactions ISO RGD:1342700 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of KIF4A gene, [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of KIF4A mRNA CTD PMID:28628672 , PMID:31601247 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of KIF4A mRNA, bisphenol A results in decreased expression of KIF4B mRNA CTD PMID:25181051 bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with Estradiol] results in increased expression of KIF4A mRNA CTD PMID:26496021 bisphenol A decreases expression ISO RGD:1551183 6480464 bisphenol A results in decreased expression of KIF4 mRNA CTD PMID:26063408 cadmium atom decreases expression ISO RGD:1342700 6480464 Cadmium results in decreased expression of KIF4A mRNA CTD PMID:21120746 , PMID:24376830 calcitriol decreases expression ISO RGD:1342700 6480464 Calcitriol results in decreased expression of KIF4A mRNA CTD PMID:21592394 calcitriol multiple interactions ISO RGD:1342700 6480464 [Testosterone co-treated with Calcitriol] results in decreased expression of KIF4A mRNA CTD PMID:21592394 carbon nanotube increases expression ISO RGD:1551183 6480464 Nanotubes more ... CTD PMID:25554681 choline multiple interactions ISO RGD:1551183 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of KIF4 mRNA CTD PMID:20938992 chromium(6+) affects expression ISO RGD:1551183 6480464 chromium hexavalent ion affects the expression of KIF4 mRNA CTD PMID:28472532 cisplatin multiple interactions ISO RGD:1342700 6480464 [Piroxicam co-treated with Cisplatin] results in increased expression of KIF4A mRNA CTD PMID:21858171 cobalt dichloride decreases expression ISO RGD:1342700 6480464 cobaltous chloride results in decreased expression of KIF4A mRNA CTD PMID:19320972 , PMID:19376846 copper atom multiple interactions ISO RGD:1342700 6480464 [NSC 689534 binds to Copper] which results in decreased expression of KIF4A mRNA CTD PMID:20971185 copper(0) multiple interactions ISO RGD:1342700 6480464 [NSC 689534 binds to Copper] which results in decreased expression of KIF4A mRNA CTD PMID:20971185 copper(II) sulfate decreases expression ISO RGD:1342700 6480464 Copper Sulfate results in decreased expression of KIF4A mRNA CTD PMID:19549813 cyclosporin A decreases expression ISO RGD:1342700 6480464 Cyclosporine results in decreased expression of KIF4A mRNA CTD PMID:20106945 more ... dexamethasone multiple interactions ISO RGD:1342700 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of KIF4A mRNA CTD PMID:28628672 dichloroacetic acid increases expression ISO RGD:1551183 6480464 Dichloroacetic Acid results in increased expression of KIF4 mRNA CTD PMID:28962523 dioxygen multiple interactions EXP 6480464 [dan-shen root extract co-treated with Andrographis paniculata extract] inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in decreased expression of KIF4A mRNA], [Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in decreased expression of KIF4A mRNA CTD PMID:33729688 disodium selenite decreases expression ISO RGD:1342700 6480464 Sodium Selenite results in decreased expression of KIF4A mRNA CTD PMID:18175754 doxorubicin affects response to substance ISO RGD:1342700 6480464 KIF4A protein affects the susceptibility to Doxorubicin CTD PMID:16217747 doxorubicin decreases expression ISO RGD:1342700 6480464 Doxorubicin results in decreased expression of KIF4A mRNA CTD PMID:30031762 enzyme inhibitor multiple interactions ISO RGD:1342700 6480464 [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of KIF4A protein CTD PMID:23301498 folic acid multiple interactions ISO RGD:1551183 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of KIF4 mRNA CTD PMID:20938992 folic acid multiple interactions ISO RGD:1342700 6480464 [Folic Acid deficiency co-treated with Methotrexate] results in decreased expression of KIF4A mRNA CTD PMID:24657277 fulvestrant multiple interactions ISO RGD:1342700 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of KIF4A gene CTD PMID:31601247 gamma-tocopherol increases expression ISO RGD:1551183 6480464 Tocopherols results in increased expression of KIF4 mRNA CTD PMID:17056531 genistein increases expression ISO RGD:1342700 6480464 Genistein results in increased expression of KIF4A mRNA CTD PMID:16474171 hydrazine decreases expression ISO RGD:1551183 6480464 hydrazine results in decreased expression of KIF4 mRNA CTD PMID:15282401 indometacin multiple interactions ISO RGD:1342700 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of KIF4A mRNA CTD PMID:28628672 isoflavones decreases expression ISO RGD:1342700 6480464 Isoflavones results in decreased expression of KIF4A mRNA CTD PMID:17374662 ivermectin decreases expression ISO RGD:1342700 6480464 Ivermectin results in decreased expression of KIF4A protein CTD PMID:32959892 L-methionine multiple interactions ISO RGD:1551183 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of KIF4 mRNA CTD PMID:20938992 lucanthone decreases expression ISO RGD:1342700 6480464 Lucanthone results in decreased expression of KIF4A mRNA CTD PMID:21148553 methapyrilene decreases methylation ISO RGD:1342700 6480464 Methapyrilene results in decreased methylation of KIF4A intron CTD PMID:30157460 methotrexate decreases expression ISO RGD:1342700 6480464 Methotrexate results in decreased expression of KIF4A mRNA CTD PMID:24657277 methotrexate multiple interactions ISO RGD:1342700 6480464 [Folic Acid deficiency co-treated with Methotrexate] results in decreased expression of KIF4A mRNA CTD PMID:24657277 methylparaben decreases expression ISO RGD:1342700 6480464 methylparaben results in decreased expression of KIF4A mRNA CTD PMID:31745603 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal decreases expression ISO RGD:1551183 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of KIF4 mRNA CTD PMID:20061341 N-methyl-4-phenylpyridinium decreases expression ISO RGD:1342700 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of KIF4A mRNA CTD PMID:24810058 N-nitrosodiethylamine increases expression ISO RGD:1551183 6480464 Diethylnitrosamine results in increased expression of KIF4 mRNA CTD PMID:17854601 N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of KIF4 mRNA CTD PMID:18164116 N-nitrosodiethylamine multiple interactions ISO RGD:1551183 6480464 RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of KIF4 mRNA] CTD PMID:17854601 N-Nitrosopyrrolidine decreases expression ISO RGD:1342700 6480464 N-Nitrosopyrrolidine results in decreased expression of KIF4A mRNA CTD PMID:32234424 omega-6 fatty acid increases expression ISO RGD:1342700 6480464 Fatty Acids, Omega-6 results in increased expression of KIF4A mRNA CTD PMID:16823509 oxaliplatin decreases expression EXP 6480464 oxaliplatin results in decreased expression of KIF4 mRNA CTD PMID:25729387 oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of KIF4 mRNA, [oxaliplatin co-treated with Topotecan] results in decreased expression of KIF4A mRNA CTD PMID:25729387 ozone decreases expression ISO RGD:1551183 6480464 Ozone results in decreased expression of KIF4A mRNA CTD PMID:24336422 palbociclib decreases expression ISO RGD:1342700 6480464 palbociclib results in decreased expression of KIF4A mRNA CTD PMID:22869556 paracetamol increases expression ISO RGD:1342700 6480464 Acetaminophen results in increased expression of KIF4A mRNA CTD PMID:22230336 paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of KIF4A mRNA CTD PMID:33387578 paracetamol decreases expression ISO RGD:1342700 6480464 Acetaminophen results in decreased expression of KIF4A mRNA CTD PMID:29067470 paraquat decreases expression EXP 6480464 Paraquat results in decreased expression of KIF4A mRNA CTD PMID:32680482 PCB138 multiple interactions ISO RGD:1551183 6480464 [2 more ... CTD PMID:25510870 phenobarbital increases expression ISO RGD:1551183 6480464 Phenobarbital results in increased expression of KIF4 mRNA CTD PMID:20403969 phenobarbital affects expression ISO RGD:1551183 6480464 Phenobarbital affects the expression of KIF4 mRNA CTD PMID:23091169 pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of KIF4 mRNA CTD PMID:19162173 pirinixic acid increases expression ISO RGD:1551183 6480464 pirinixic acid results in increased expression of KIF4 mRNA CTD PMID:23811191 pirinixic acid multiple interactions ISO RGD:1342700 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of KIF4A mRNA CTD PMID:19710929 piroxicam multiple interactions ISO RGD:1342700 6480464 [Piroxicam co-treated with Cisplatin] results in increased expression of KIF4A mRNA CTD PMID:21858171 potassium chromate multiple interactions ISO RGD:1342700 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of KIF4A mRNA CTD PMID:22079256 potassium chromate decreases expression ISO RGD:1342700 6480464 potassium chromate(VI) results in decreased expression of KIF4A mRNA CTD PMID:22079256 pregnenolone 16alpha-carbonitrile increases expression ISO RGD:1551183 6480464 Pregnenolone Carbonitrile results in increased expression of KIF4 mRNA CTD PMID:22698814 progesterone increases expression ISO RGD:1342700 6480464 Progesterone results in increased expression of KIF4A mRNA CTD PMID:18070364 progesterone decreases expression ISO RGD:1342700 6480464 Progesterone results in decreased expression of KIF4A mRNA CTD PMID:21795739 propanal decreases expression ISO RGD:1342700 6480464 propionaldehyde results in decreased expression of KIF4A mRNA CTD PMID:26079696 quercetin decreases expression ISO RGD:1342700 6480464 Quercetin results in decreased expression of KIF4A mRNA CTD PMID:21632981 rotenone decreases expression EXP 6480464 Rotenone results in decreased expression of KIF4A mRNA CTD PMID:28374803 silicon dioxide increases expression ISO RGD:1551183 6480464 Silicon Dioxide results in increased expression of KIF4 mRNA CTD PMID:29341224 sodium arsenite decreases expression ISO RGD:1551183 6480464 sodium arsenite results in decreased expression of KIF4 mRNA CTD PMID:30130555 sodium arsenite increases expression ISO RGD:1342700 6480464 sodium arsenite results in increased expression of KIF4A mRNA CTD PMID:29301061 sunitinib decreases expression ISO RGD:1342700 6480464 Sunitinib results in decreased expression of KIF4A mRNA CTD PMID:31533062 tamoxifen affects expression ISO RGD:1551183 6480464 Tamoxifen affects the expression of KIF4 mRNA CTD PMID:17555576 tert-butyl hydroperoxide increases expression ISO RGD:1551183 6480464 tert-Butylhydroperoxide results in increased expression of KIF4 mRNA CTD PMID:15003993 testosterone multiple interactions ISO RGD:1342700 6480464 [Testosterone co-treated with Calcitriol] results in decreased expression of KIF4A mRNA CTD PMID:21592394 testosterone decreases expression ISO RGD:1342700 6480464 Testosterone results in decreased expression of KIF4A mRNA CTD PMID:21592394 tetrachloromethane affects expression ISO RGD:1551183 6480464 Carbon Tetrachloride affects the expression of KIF4 mRNA CTD PMID:17484886 tetrachloromethane increases expression ISO RGD:1551183 6480464 Carbon Tetrachloride results in increased expression of KIF4 mRNA CTD PMID:31919559 thapsigargin decreases expression ISO RGD:1342700 6480464 Thapsigargin results in decreased expression of KIF4A mRNA CTD PMID:22378314 thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of KIF4A mRNA CTD PMID:34492290 titanium dioxide increases expression ISO RGD:1551183 6480464 titanium dioxide results in increased expression of KIF4 mRNA CTD PMID:23557971 tocopherol increases expression ISO RGD:1551183 6480464 Tocopherols results in increased expression of KIF4 mRNA CTD PMID:17056531 topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of KIF4 mRNA, [oxaliplatin co-treated with Topotecan] results in decreased expression of KIF4A mRNA CTD PMID:25729387 topotecan decreases expression EXP 6480464 Topotecan results in decreased expression of KIF4A mRNA CTD PMID:25729387 trichloroethene decreases expression EXP 6480464 Trichloroethylene results in decreased expression of KIF4A mRNA CTD PMID:33387578 triclosan decreases expression ISO RGD:1342700 6480464 Triclosan results in decreased expression of KIF4A mRNA CTD PMID:30510588 trimellitic anhydride increases expression ISO RGD:1551183 6480464 trimellitic anhydride results in increased expression of KIF4 mRNA CTD PMID:19042947 troglitazone decreases expression ISO RGD:1342700 6480464 troglitazone results in decreased expression of KIF4A mRNA CTD PMID:19140230 tungsten decreases expression ISO RGD:1551183 6480464 Tungsten results in decreased expression of KIF4 mRNA CTD PMID:30912803 tunicamycin decreases expression ISO RGD:1342700 6480464 Tunicamycin results in decreased expression of KIF4A mRNA CTD PMID:22378314 urethane increases expression ISO RGD:1342700 6480464 Urethane results in increased expression of KIF4A mRNA CTD PMID:28818685 valproic acid decreases methylation ISO RGD:1342700 6480464 Valproic Acid results in decreased methylation of KIF4A gene CTD PMID:29154799 valproic acid decreases expression ISO RGD:1342700 6480464 Valproic Acid results in decreased expression of KIF4A mRNA CTD PMID:28001369 vincaleukoblastine affects response to substance ISO RGD:1342700 6480464 KIF4A protein affects the susceptibility to Vinblastine CTD PMID:16217747 zoledronic acid decreases expression ISO RGD:1342700 6480464 zoledronic acid results in decreased expression of KIF4A mRNA CTD PMID:24714768
