Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Dgkh | Rat | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of DGKH mRNA] | CTD | PMID:31150632 | Dgkh | Rat | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | DGKH (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of DGKH mRNA | CTD | PMID:22079256 | Dgkh | Rat | (-)-epigallocatechin 3-gallate | increases expression | ISO | DGKH (Homo sapiens) | 6480464 | epigallocatechin gallate results in increased expression of DGKH mRNA | CTD | PMID:22079256 | Dgkh | Rat | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of DGKH mRNA | CTD | PMID:29097150 | Dgkh | Rat | 17beta-estradiol | increases expression | ISO | DGKH (Homo sapiens) | 6480464 | Estradiol results in increased expression of DGKH mRNA | CTD | PMID:23019147 and PMID:31614463 | Dgkh | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Dgkh (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of DGKH mRNA | CTD | PMID:26377647 | Dgkh | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of DGKH mRNA | CTD | PMID:32109520 | Dgkh | Rat | 2,3,7,8-Tetrachlorodibenzofuran | decreases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:32109520 | Dgkh | Rat | 3,3',5,5'-tetrabromobisphenol A | increases expression | ISO | Dgkh (Mus musculus) | 6480464 | tetrabromobisphenol A results in increased expression of DGKH mRNA | CTD | PMID:25172293 | Dgkh | Rat | 3,4-methylenedioxymethamphetamine | decreases expression | ISO | Dgkh (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of DGKH mRNA | CTD | PMID:26251327 | Dgkh | Rat | 4,4'-sulfonyldiphenol | decreases methylation | ISO | Dgkh (Mus musculus) | 6480464 | bisphenol S results in decreased methylation of DGKH exon | CTD | PMID:33297965 | Dgkh | Rat | 4-hydroxynon-2-enal | decreases expression | ISO | Dgkh (Mus musculus) | 6480464 | 4-hydroxy-2-nonenal results in decreased expression of DGKH mRNA | CTD | PMID:19191707 | Dgkh | Rat | 4-hydroxyphenyl retinamide | increases expression | ISO | Dgkh (Mus musculus) | 6480464 | Fenretinide results in increased expression of DGKH mRNA | CTD | PMID:28973697 | Dgkh | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of DGKH mRNA | CTD | PMID:24780913 | Dgkh | Rat | acrolein | multiple interactions | ISO | DGKH (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of DGKH mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of DGKH mRNA | CTD | PMID:32699268 | Dgkh | Rat | aflatoxin B1 | increases methylation | ISO | DGKH (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of DGKH gene | CTD | PMID:27153756 | Dgkh | Rat | all-trans-retinoic acid | decreases expression | ISO | DGKH (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of DGKH mRNA | CTD | PMID:33167477 | Dgkh | Rat | alpha-pinene | multiple interactions | ISO | DGKH (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of DGKH mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of DGKH mRNA | CTD | PMID:32699268 | Dgkh | Rat | aristolochic acid A | decreases expression | ISO | DGKH (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of DGKH mRNA | CTD | PMID:33212167 | Dgkh | Rat | arsenite(3-) | multiple interactions | ISO | DGKH (Homo sapiens) | 6480464 | arsenite inhibits the reaction [G3BP1 protein binds to DGKH mRNA] | CTD | PMID:32406909 | Dgkh | Rat | benzo[a]pyrene | decreases methylation | ISO | Dgkh (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased methylation of DGKH intron and Benzo(a)pyrene results in decreased methylation of DGKH promoter | CTD | PMID:27901495 | Dgkh | Rat | benzo[a]pyrene | increases expression | ISO | DGKH (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of DGKH mRNA | CTD | PMID:32234424 | Dgkh | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of DGKH mRNA | CTD | PMID:25181051 | Dgkh | Rat | bisphenol A | increases expression | ISO | Dgkh (Mus musculus) | 6480464 | bisphenol A results in increased expression of DGKH mRNA | CTD | PMID:35598803 | Dgkh | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of DGKH mRNA | CTD | PMID:30816183 | Dgkh | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of DGKH mRNA | CTD | PMID:29097150 | Dgkh | Rat | cadmium dichloride | increases expression | ISO | DGKH (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of DGKH mRNA | CTD | PMID:38568856 | Dgkh | Rat | calcitriol | decreases expression | ISO | DGKH (Homo sapiens) | 6480464 | Calcitriol results in decreased expression of DGKH mRNA | CTD | PMID:21592394 | Dgkh | Rat | calcitriol | multiple interactions | ISO | DGKH (Homo sapiens) | 6480464 | [Testosterone co-treated with Calcitriol] results in decreased expression of DGKH mRNA | CTD | PMID:21592394 | Dgkh | Rat | carbon nanotube | increases expression | ISO | Dgkh (Mus musculus) | 6480464 | Nanotubes and Carbon results in increased expression of DGKH mRNA | CTD | PMID:25554681 | Dgkh | Rat | chlorpyrifos | decreases expression | ISO | Dgkh (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of DGKH mRNA | CTD | PMID:37019170 | Dgkh | Rat | chromium(6+) | affects expression | ISO | Dgkh (Mus musculus) | 6480464 | chromium hexavalent ion affects the expression of DGKH mRNA | CTD | PMID:24374135 | Dgkh | Rat | chromium(6+) | decreases expression | ISO | DGKH (Homo sapiens) | 6480464 | chromium hexavalent ion results in decreased expression of DGKH mRNA | CTD | PMID:30690063 | Dgkh | Rat | copper atom | multiple interactions | ISO | DGKH (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in increased expression of DGKH mRNA | CTD | PMID:20971185 | Dgkh | Rat | copper(0) | multiple interactions | ISO | DGKH (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in increased expression of DGKH mRNA | CTD | PMID:20971185 | Dgkh | Rat | Cuprizon | decreases expression | EXP | | 6480464 | Cuprizone results in decreased expression of DGKH mRNA | CTD | PMID:26577399 | Dgkh | Rat | cyclosporin A | increases expression | ISO | DGKH (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of DGKH mRNA | CTD | PMID:20106945 | Dgkh | Rat | Dibutyl phosphate | affects expression | ISO | DGKH (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of DGKH mRNA | CTD | PMID:37042841 | Dgkh | Rat | dichloroacetic acid | increases expression | ISO | Dgkh (Mus musculus) | 6480464 | Dichloroacetic Acid results in increased expression of DGKH mRNA | CTD | PMID:28962523 | Dgkh | Rat | endosulfan | increases expression | EXP | | 6480464 | Endosulfan results in increased expression of DGKH mRNA | CTD | PMID:29391264 | Dgkh | Rat | entinostat | increases expression | ISO | DGKH (Homo sapiens) | 6480464 | entinostat results in increased expression of DGKH mRNA | CTD | PMID:27188386 | Dgkh | Rat | folic acid | decreases expression | ISO | Dgkh (Mus musculus) | 6480464 | Folic Acid results in decreased expression of DGKH mRNA | CTD | PMID:25629700 | Dgkh | Rat | FR900359 | decreases phosphorylation | ISO | DGKH (Homo sapiens) | 6480464 | FR900359 results in decreased phosphorylation of DGKH protein | CTD | PMID:37730182 | Dgkh | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of DGKH mRNA | CTD | PMID:33387578 | Dgkh | Rat | indometacin | increases expression | EXP | | 6480464 | Indomethacin results in increased expression of DGKH mRNA | CTD | PMID:36868495 | Dgkh | Rat | methamphetamine | increases expression | ISO | Dgkh (Mus musculus) | 6480464 | Methamphetamine results in increased expression of DGKH mRNA | CTD | PMID:26307267 | Dgkh | Rat | methotrexate | decreases expression | ISO | DGKH (Homo sapiens) | 6480464 | Methotrexate results in decreased expression of DGKH mRNA | CTD | PMID:24449571 | Dgkh | Rat | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of DGKH gene | CTD | PMID:35440735 | Dgkh | Rat | nickel sulfate | decreases expression | ISO | DGKH (Homo sapiens) | 6480464 | nickel sulfate results in decreased expression of DGKH mRNA | CTD | PMID:22714537 | Dgkh | Rat | ozone | multiple interactions | ISO | DGKH (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of DGKH mRNA more ... | CTD | PMID:32699268 | Dgkh | Rat | paracetamol | increases expression | ISO | DGKH (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of DGKH mRNA | CTD | PMID:29067470 | Dgkh | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of DGKH mRNA | CTD | PMID:33387578 | Dgkh | Rat | paraquat | increases expression | ISO | Dgkh (Mus musculus) | 6480464 | Paraquat results in increased expression of DGKH mRNA | CTD | PMID:22563483 | Dgkh | Rat | perfluorononanoic acid | increases expression | ISO | DGKH (Homo sapiens) | 6480464 | perfluoro-n-nonanoic acid results in increased expression of DGKH mRNA | CTD | PMID:25812627 | Dgkh | Rat | perfluorooctanoic acid | increases expression | ISO | Dgkh (Mus musculus) | 6480464 | perfluorooctanoic acid results in increased expression of DGKH mRNA | CTD | PMID:30711707 | Dgkh | Rat | perfluorooctanoic acid | increases expression | ISO | DGKH (Homo sapiens) | 6480464 | perfluorooctanoic acid results in increased expression of DGKH mRNA | CTD | PMID:25812627 | Dgkh | Rat | pirinixic acid | multiple interactions | ISO | Dgkh (Mus musculus) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of DGKH mRNA | CTD | PMID:19710929 | Dgkh | Rat | pirinixic acid | increases expression | ISO | Dgkh (Mus musculus) | 6480464 | pirinixic acid results in increased expression of DGKH mRNA | CTD | PMID:18301758 and PMID:23811191 | Dgkh | Rat | potassium chromate | multiple interactions | ISO | DGKH (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of DGKH mRNA | CTD | PMID:22079256 | Dgkh | Rat | potassium chromate | decreases expression | ISO | DGKH (Homo sapiens) | 6480464 | potassium chromate(VI) results in decreased expression of DGKH mRNA | CTD | PMID:22079256 and PMID:22714537 | Dgkh | Rat | resveratrol | multiple interactions | ISO | DGKH (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of DGKH mRNA | CTD | PMID:23557933 | Dgkh | Rat | sodium arsenite | increases expression | ISO | DGKH (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of DGKH mRNA | CTD | PMID:38568856 | Dgkh | Rat | streptozocin | multiple interactions | EXP | | 6480464 | [Streptozocin co-treated with Dietary Fats] results in decreased expression of DGKH mRNA | CTD | PMID:20665664 | Dgkh | Rat | testosterone | multiple interactions | ISO | DGKH (Homo sapiens) | 6480464 | [Testosterone co-treated with Calcitriol] results in decreased expression of DGKH mRNA | CTD | PMID:21592394 | Dgkh | Rat | testosterone | decreases expression | ISO | DGKH (Homo sapiens) | 6480464 | Testosterone results in decreased expression of DGKH mRNA | CTD | PMID:21592394 | Dgkh | Rat | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of DGKH mRNA] | CTD | PMID:31150632 | Dgkh | Rat | tetrachloromethane | increases expression | ISO | Dgkh (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of DGKH mRNA | CTD | PMID:31919559 | Dgkh | Rat | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of DGKH mRNA | CTD | PMID:31150632 | Dgkh | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of DGKH mRNA | CTD | PMID:34492290 | Dgkh | Rat | thiram | increases expression | ISO | DGKH (Homo sapiens) | 6480464 | Thiram results in increased expression of DGKH mRNA | CTD | PMID:38568856 | Dgkh | Rat | titanium dioxide | decreases methylation | ISO | Dgkh (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of DGKH promoter | CTD | PMID:35295148 | Dgkh | Rat | triphenyl phosphate | affects expression | ISO | DGKH (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of DGKH mRNA | CTD | PMID:37042841 | Dgkh | Rat | valproic acid | decreases methylation | ISO | DGKH (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of DGKH gene | CTD | PMID:29154799 | Dgkh | Rat | valproic acid | decreases expression | EXP | | 6480464 | Valproic Acid results in decreased expression of DGKH mRNA | CTD | PMID:29427782 | Dgkh | Rat | valproic acid | affects splicing | EXP | | 6480464 | Valproic Acid affects the splicing of DGKH mRNA | CTD | PMID:29427782 | Dgkh | Rat | vinclozolin | increases expression | EXP | | 6480464 | vinclozolin results in increased expression of DGKH mRNA | CTD | PMID:22615374 | |