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Gene: Trh (thyrotropin releasing hormone) Rattus norvegicus
Symbol: Trh
Name: thyrotropin releasing hormone
RGD ID: 3903
Description: Exhibits thyrotropin-releasing hormone activity. Involved in several processes, including histamine metabolic process; regulation of secretion; and response to corticosterone. Localizes to nucleus; plasma membrane; and secretory granule. Used to study hypertension. Biomarker of hypothyroidism. Orthologous to human TRH (thyrotropin releasing hormone); INTERACTS WITH (+)-pilocarpine; 1,3,5-trinitro-1,3,5-triazinane; 17beta-estradiol.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: pro-thyrotropin-releasing hormone; Pro-TRH; prothyroliberin; protirelin; THR; thyrotropin-releasing factor; thyrotropin-releasing hormone; Trf; TRH01; Tryrotropin releasing hormone; TSH-releasing factor
Homo sapiens (human) : TRH (thyrotropin releasing hormone)  HGNC  Alliance
Mus musculus (house mouse) : Trh (thyrotropin releasing hormone)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Trh (thyrotropin releasing hormone)
Pan paniscus (bonobo/pygmy chimpanzee) : TRH (thyrotropin releasing hormone)
Canis lupus familiaris (dog) : TRH (thyrotropin releasing hormone)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Trh (thyrotropin releasing hormone)
Sus scrofa (pig) : TRH (thyrotropin releasing hormone)
Chlorocebus sabaeus (African green monkey) : TRH (thyrotropin releasing hormone)
Heterocephalus glaber (naked mole-rat) : Trh (thyrotropin releasing hormone)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.04124,110,716 - 124,113,242 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4124,110,716 - 124,113,242 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04189,116,103 - 189,151,296 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44126,425,212 - 126,427,670 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14126,670,058 - 126,672,508 (-)NCBI
Celera4113,659,987 - 113,662,513 (-)NCBICelera
Cytogenetic Map4q34NCBI
RH 3.4 Map4736.33RGD
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Trh
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3903
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.