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Gene: Slc25a4 (solute carrier family 25 member 4) Rattus norvegicus
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Symbol: Slc25a4
Name: solute carrier family 25 member 4
Description: Exhibits enzyme binding activity. Involved in several processes, including aging; negative regulation of cardiac muscle cell apoptotic process; and negative regulation of mitochondrial membrane permeability involved in apoptotic process. Localizes to the membrane raft; mitochondrial inner membrane; and mitochondrial outer membrane. Biomarker of alcoholic cardiomyopathy. Human ortholog(s) of this gene implicated in intrinsic cardiomyopathy (multiple); mitochondrial DNA depletion syndrome (multiple); and mitochondrial myopathy (multiple). Orthologous to human SLC25A4 (solute carrier family 25 member 4); PARTICIPATES IN electron transport chain pathway; calcium/calcium-mediated signaling pathway; Huntington's disease pathway; INTERACTS WITH 1,3-dinitrobenzene; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: adenine nucleotide translocator 1; adenine nucleotide translocator), member 4; ADP,ATP carrier protein 1; ADP/ATP translocase 1; ANT 1; Ant1; mitochondrial adenine nucleotide translocator; solute carrier family 25 (mitochondrial adenine nucleotide translocator) member 4; solute carrier family 25 (mitochondrial carrier; solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4; solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
Orthologs:
Homo sapiens (human) : SLC25A4 (solute carrier family 25 member 4)  HGNC  Alliance
Mus musculus (house mouse) : Slc25a4 (solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc25a4 (solute carrier family 25 member 4)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC25A4 (solute carrier family 25 member 4)
Canis lupus familiaris (dog) : SLC25A4 (solute carrier family 25 member 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc25a4 (solute carrier family 25 member 4)
Sus scrofa (pig) : SLC25A4 (solute carrier family 25 member 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01649,266,903 - 49,270,698 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01648,981,600 - 48,985,395 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41649,353,476 - 49,357,271 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11649,353,550 - 49,357,346 (+)NCBI
Celera1644,072,219 - 44,076,014 (+)NCBICelera
Cytogenetic Map16q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Slc25a4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620352
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-08-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.