 Gene-Chemical Interaction Annotations | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Gene Ontology AnnotationsMolecular Pathway Annotations |
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Analyze GeneStrainQTL List |
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Gene Ontology AnnotationsMolecular Pathway AnnotationsDisease Annotations
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Gene-Chemical Interaction Annotations
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Gene Ontology AnnotationsBiological Process
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Cellular Component
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Molecular Function
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Molecular Pathway Annotations
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References - curated| 1. | Anger AM, etal., Nature. 2013 May 2;497(7447):80-5. doi: 10.1038/nature12104. |
| 2. | Cheng D, etal., Mol Cell Proteomics. 2006 Jun;5(6):1158-70. doi: 10.1074/mcp.D500009-MCP200. Epub 2006 Feb 28. |
| 3. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
| 4. | Hultin T Biochim Biophys Acta. 1986 Aug 15;872(3):226-35. |
| 5. | MGD data from the GO Consortium |
| 6. | Primiano T, etal., Carcinogenesis 1996 Nov;17(11):2297-303. |
| 7. | RGD automated data pipeline |
| 8. | RGD automated import pipeline for gene-chemical interactions |
| 9. | RGD comprehensive gene curation |
| 10. | Sommer W, etal., Mol Psychiatry. 2001 Jan;6(1):103-8; 5. |
| 11. | Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11. |
| 12. | Topalidou I, etal., PLoS Genet. 2016 May 18;12(5):e1006074. doi: 10.1371/journal.pgen.1006074. eCollection 2016 May. |
| 13. | Tsurugi K, etal., J Biol Chem. 1978 Feb 10;253(3):946-55. |
References - uncuratedGenomics
Comparative Map Data| Rpl18a (Rattus norvegicus - Norway rat) |
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| RPL18A (Homo sapiens - human) |
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| Rpl18a (Mus musculus - house mouse) |
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| Rpl18a (Chinchilla lanigera - long-tailed chinchilla) |
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| RPL18A (Pan paniscus - bonobo/pygmy chimpanzee) |
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| RPL18A (Canis lupus familiaris - dog) |
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| Rpl18a (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| RPL18A (Sus scrofa - pig) |
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| RPL18A (Chlorocebus sabaeus - African green monkey) |
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| Rpl18a (Heterocephalus glaber - naked mole-rat) |
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Position Markers| PMC83998P1 |
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| MARC_4117-4118:991938388:1 |
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| RH125499 |
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| D14S105E |
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QTLs in Region (Rnor_6.0)| The following QTLs overlap with this region. |  | Full Report | | CSV | | TAB | | Printer | | Gviewer |
miRNA Target Status
Predicted Target Of
| The detailed report is available here: | | Full Report | | CSV | | TAB | | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
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Expression
RNA-SEQ ExpressionHigh: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM
| alimentary part of gastrointestinal system | circulatory system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | musculoskeletal system | nervous system | renal system | reproductive system | respiratory system | appendage | |
| High | 3 | 22 | 24 | 18 | 16 | 18 | 41 | 18 | 32 | 2 | |||
| Medium | 21 | 33 | 23 | 3 | 23 | 8 | 11 | 33 | 17 | 9 | 9 | 8 | |
| Low | |||||||||||||
| Below cutoff |
View RNA-SEQ Expression Data
Sequence
Nucleotide Sequences| RefSeq Transcripts | NM_212510 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| GenBank Nucleotide | AABR07024873 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| AAHX01086840 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| BC058498 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| CH474031 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| FQ209874 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| FQ209881 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| FQ209956 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| FQ210713 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| FQ216877 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| FQ221165 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| FQ221243 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| FQ221413 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| FQ221458 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| FQ221831 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| FQ222162 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| FQ222289 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| FQ222457 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| FQ222474 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| FQ222662 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| FQ223818 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| FQ226007 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| FQ228440 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
Reference Sequences
| RefSeq Acc Id: | ENSRNOT00000025421 ⟹ ENSRNOP00000025421 | ||||||||
| RefSeq Status: | |||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | NM_212510 ⟹ NP_997675 | ||||||||||||||||||||
| RefSeq Status: | PROVISIONAL | ||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||
| Position: |
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| Sequence: |
CCTTTTGTGAGTGGCAGTGAACGAGCACGCACTGCTATGAAGGCGTCGGGCACGCTTCGGGAGThide sequence |
Protein Sequences| Protein RefSeqs | NP_997675 | (Get FASTA) | NCBI Sequence Viewer |
| GenBank Protein | AAH58498 | (Get FASTA) | NCBI Sequence Viewer |
| EDL90752 | (Get FASTA) | NCBI Sequence Viewer | |
| P62718 | (Get FASTA) | NCBI Sequence Viewer |
Reference Sequences
| RefSeq Acc Id: | NP_997675 ⟸ NM_212510 |
| - UniProtKB: | P62718 (UniProtKB/Swiss-Prot) |
| - Sequence: |
MKASGTLREYKVVGRCLPTPKCHTPPLYRMRIFAPNHVVAKSRFWYFVSQLKKMKKSSGEIVYChide sequence |
| RefSeq Acc Id: | ENSRNOP00000025421 ⟸ ENSRNOT00000025421 |
TranscriptomePromoters| RGD ID: | 13700011 | ||||||||
| Promoter ID: | EPDNEW_R10534 | ||||||||
| Type: | multiple initiation site | ||||||||
| Name: | Rpl18a_1 | ||||||||
| Description: | ribosomal protein L18A | ||||||||
| SO ACC ID: | SO:0000170 | ||||||||
| Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
| Experiment Methods: | Single-end sequencing. | ||||||||
| Position: |
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Strain Variation
Strain Sequence Variants (Rnor 6.0)
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Damaging VariantsAssembly: Rnor_5.0
| Chromosome | Start Pos | End Pos | Reference Nucleotide | Variant Nucleotide | Variant Type | Strain |
| 16 | 20152721 | 20152722 | T | C | snv | ZF (KyushuU) |
Additional Information
External Database Links| Database | Acc Id | Source(s) |
| AGR Gene | RGD:1302976 | AgrOrtholog |
| Ensembl Genes | ENSRNOG00000018795 | Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot |
| Ensembl Protein | ENSRNOP00000025421 | ENTREZGENE, UniProtKB/Swiss-Prot |
| Ensembl Transcript | ENSRNOT00000025421 | ENTREZGENE, UniProtKB/Swiss-Prot |
| IMAGE_CLONE | IMAGE:6919102 | IMAGE-MGC_LOAD |
| InterPro | 50S_L18Ae/Ribosomal_L18a/L20 | UniProtKB/Swiss-Prot |
| Ribosomal_L18a//L18Ae/LX | UniProtKB/Swiss-Prot | |
| Ribosomal_L18a/L20_eukaryotes | UniProtKB/Swiss-Prot | |
| KEGG Report | rno:290641 | UniProtKB/Swiss-Prot |
| MGC_CLONE | MGC:72957 | IMAGE-MGC_LOAD |
| NCBI Gene | 290641 | ENTREZGENE |
| PANTHER | PTHR10052 | UniProtKB/Swiss-Prot |
| Pfam | Ribosomal_L18A | UniProtKB/Swiss-Prot |
| PhenoGen | Rpl18a | PhenoGen |
| PIRSF | Ribosomal_L18a | UniProtKB/Swiss-Prot |
| UniGene | Rn.105821 | ENTREZGENE |
| Rn.91296 | ENTREZGENE | |
| UniProt | P62718 | ENTREZGENE, UniProtKB/Swiss-Prot |
| UniProt Secondary | P11249 | UniProtKB/Swiss-Prot |
Nomenclature History| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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| 2008-03-06 | Rpl18a | ribosomal protein L18A | MGC72957 | similar to 60S ribosomal protein L18a | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
| 2005-02-14 | MGC72957 | similar to 60S ribosomal protein L18a | Symbol and Name status set to provisional | 70820 | PROVISIONAL |
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| More on Rpl18a | |
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Alliance Gene |
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NCBI Gene |
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Ensembl Gene |
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JBrowse: rn5 rn6 |
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NCBI Genome Data Viewer |
| RGD Object Information | |
| RGD ID: | 1302976 |
| Created: | 2004-12-03 |
| Species: | Rattus norvegicus |
| Last Modified: | 2020-03-25 |
| Status: | ACTIVE |
