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Gene: Il11 (interleukin 11) Rattus norvegicus
Symbol: Il11
Name: interleukin 11
RGD ID: 621475
Description: Predicted to have cytokine activity; growth factor activity; and interleukin-11 receptor binding activity. Predicted to be involved in several processes, including negative regulation of hormone secretion; positive regulation of protein phosphorylation; and positive regulation of transcription by RNA polymerase II. Predicted to localize to cytoplasm. Orthologous to human IL11 (interleukin 11); PARTICIPATES IN cytokine mediated signaling pathway; Jak-Stat signaling pathway; rheumatoid arthritis pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 2-amino-2-deoxy-D-glucopyranose; 5-aza-2'-deoxycytidine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: IL-11; interleukin-11
Homo sapiens (human) : IL11 (interleukin 11)  HGNC  Alliance
Mus musculus (house mouse) : Il11 (interleukin 11)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Il11 (interleukin 11)
Pan paniscus (bonobo/pygmy chimpanzee) : IL11 (interleukin 11)
Canis lupus familiaris (dog) : IL11 (interleukin 11)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Il11 (interleukin 11)
Sus scrofa (pig) : IL11 (interleukin 11)
Chlorocebus sabaeus (African green monkey) : IL11 (interleukin 11)
Heterocephalus glaber (naked mole-rat) : Il11 (interleukin 11)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0172,636,959 - 72,643,255 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl172,635,267 - 72,643,255 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0175,891,524 - 75,902,590 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4167,784,584 - 67,795,141 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1167,862,694 - 68,157,244 (+)NCBI
Celera168,048,383 - 68,054,698 (-)NCBICelera
Cytogenetic Map1q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Il11
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621475
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-11-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.