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Gene: Anxa5 (annexin A5) Rattus norvegicus
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Symbol: Anxa5
Name: annexin A5
Description: Exhibits several functions, including calcium transmembrane transporter activity, phosphorylative mechanism; calcium-dependent phospholipid binding activity; and receptor tyrosine kinase binding activity. Involved in several processes, including cellular response to gonadotropin-releasing hormone; cellular response to lead ion; and negative regulation of prolactin secretion. Localizes to several cellular components, including Z disc; intercalated disc; and perikaryon. Biomarker of several diseases, including Wilson disease; cryptorchidism; hyperthyroidism; hypothyroidism; and myocardial infarction. Human ortholog(s) of this gene implicated in autoimmune disease of the nervous system; myocardial infarction; and systemic scleroderma. Orthologous to human ANXA5 (annexin A5); INTERACTS WITH 1,3,5-trinitro-1,3,5-triazinane; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: anchorin CII; annexin 5; Annexin V; annexin-5; Anx5; calphobindin I; CBP-I; endonexin II; LC5; lipocortin V; MGC93655; PAP-I; placental anticoagulant protein 4; placental anticoagulant protein I; PP4; thromboplastin inhibitor; VAC-alpha; vascular anticoagulant-alpha
Orthologs:
Homo sapiens (human) : ANXA5 (annexin A5)  HGNC  Alliance
Mus musculus (house mouse) : Anxa5 (annexin A5)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Anxa5 (annexin A5)
Pan paniscus (bonobo/pygmy chimpanzee) : ANXA5 (annexin A5)
Canis lupus familiaris (dog) : ANXA5 (annexin A5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Anxa5 (annexin A5)
Sus scrofa (pig) : ANXA5 (annexin A5)
Chlorocebus sabaeus (African green monkey) : ANXA5 (annexin A5)
Heterocephalus glaber (naked mole-rat) : Anxa5 (annexin A5)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02123,162,477 - 123,194,730 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2123,162,461 - 123,193,130 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02142,777,624 - 142,808,420 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42122,949,210 - 122,979,757 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12122,894,171 - 122,924,719 (-)NCBI
Celera2114,271,560 - 114,302,133 (-)NCBICelera
Cytogenetic Map2q25NCBI
RH 3.4 Map2623.7RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Anxa5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2120
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.