Gene: Gfpt1 (glutamine fructose-6-phosphate transaminase 1) Rattus norvegicus
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Symbol: Gfpt1
Name: glutamine fructose-6-phosphate transaminase 1
Description: ENCODES a protein that exhibits amino acid binding; carbohydrate binding; glutamine-fructose-6-phosphate transaminase (isomerizing) activity; INVOLVED IN cellular response to insulin stimulus; fructose 6-phosphate metabolic process; glucosamine biosynthetic process; PARTICIPATES IN hexosamine biosynthetic pathway; 2-hydroxyglutaric aciduria pathway; amino sugar metabolic pathway; ASSOCIATED WITH Diabetes Mellitus, Experimental ; familial hyperlipidemia; hyperinsulinism; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,6-dinitrotoluene
AGR Description: Exhibits amino acid binding activity, carbohydrate binding activity, and glutamine-fructose-6-phosphate transaminase (isomerizing) activity; involved in several processes, including UDP-N-acetylglucosamine metabolic process, cellular response to insulin stimulus, and fructose 6-phosphate metabolic process; biomarker of familial hyperlipidemia and hyperinsulinism; orthologous to human GFPT1 (glutamine--fructose-6-phosphate transaminase 1).
Merged Description: Exhibits amino acid binding activity, carbohydrate binding activity, and glutamine-fructose-6-phosphate transaminase (isomerizing) activity; involved in several processes, including UDP-N-acetylglucosamine metabolic process, cellular response to insulin stimulus, and fructose 6-phosphate metabolic process; biomarker of familial hyperlipidemia and hyperinsulinism; orthologous to human GFPT1 (glutamine--fructose-6-phosphate transaminase 1); PARTICIPATES IN hexosamine biosynthetic pathway; 2-hydroxyglutaric aciduria pathway; amino sugar metabolic pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: D-fructose-6-phosphate amidotransferase 1; GFA; GFAT; GFAT 1; GFAT1; GFAT1m; Gfpt; glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1; glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1; glutamine:fructose 6 phosphate amidotransferase 1; glutamine:fructose-6-phosphate amidotransferase 1; hexosephosphate aminotransferase 1; MGC95214
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.04118,852,046 - 118,901,583 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04183,421,338 - 183,470,867 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44121,204,274 - 121,250,160 (+)NCBIRGSC3.4rn4RGSC3.4
Celera4108,466,461 - 108,512,263 (+)NCBICelera
Cytogenetic Map4q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Gfpt1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1549703
Created: 2005-09-15
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.