1,2-dimethylhydrazine multiple interactions ISO RGD:732646 6480464 [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of TKT mRNA CTD PMID:22206623 1,2-dimethylhydrazine affects expression ISO RGD:732646 6480464 1, 2-Dimethylhydrazine affects the expression of TKT mRNA CTD PMID:22206623 1,3-dinitrobenzene increases expression EXP 6480464 3-dinitrobenzene results in increased expression of TKT mRNA CTD PMID:21983209 1-chloro-2,4-dinitrobenzene increases metabolic processing ISO RGD:732645 6480464 Dinitrochlorobenzene results in increased metabolism of TKT protein CTD PMID:29267982 1-naphthyl isothiocyanate increases expression EXP 6480464 1-Naphthylisothiocyanate results in increased expression of TKT mRNA CTD PMID:30723492 17alpha-ethynylestradiol increases expression ISO RGD:732646 6480464 Ethinyl Estradiol results in increased expression of TKT mRNA CTD PMID:17942748 17alpha-ethynylestradiol multiple interactions ISO RGD:732646 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of TKT mRNA CTD PMID:17942748 17beta-estradiol multiple interactions EXP 6480464 [bisphenol A co-treated with Estradiol] results in decreased expression of TKT mRNA CTD PMID:26496021 17beta-estradiol multiple interactions ISO RGD:732645 6480464 [Estradiol co-treated with TGFB1 protein] results in decreased expression of TKT mRNA CTD PMID:30165855 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:732646 6480464 [Tetrachlorodibenzodioxin binds to AHR protein] which results in increased expression of TKT mRNA, [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of TKT mRNA CTD PMID:16214954 , PMID:17942748 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:732646 6480464 Tetrachlorodibenzodioxin affects the expression of TKT mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of TKT mRNA CTD PMID:16054898 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:732646 6480464 Tetrachlorodibenzodioxin results in increased expression of TKT mRNA CTD PMID:18796159 2,4-dibromophenyl 2,4,5-tribromophenyl ether increases expression EXP 6480464 2 more ... CTD PMID:19954255 2,4-dibromophenyl 2,4,5-tribromophenyl ether increases expression ISO RGD:732646 6480464 2 more ... CTD PMID:18550172 2-acetamidofluorene multiple interactions EXP 6480464 [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of TKT mRNA, [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of TKT mRNA CTD PMID:14656948 , PMID:16158176 2-hydroxypropanoic acid increases expression ISO RGD:732645 6480464 Lactic Acid results in increased expression of TKT mRNA CTD PMID:30851411 3-chloropropane-1,2-diol increases expression EXP 6480464 alpha-Chlorohydrin results in increased expression of TKT mRNA CTD PMID:28522335 3-chloropropane-1,2-diol decreases expression EXP 6480464 alpha-Chlorohydrin analog results in decreased expression of TKT protein, alpha-Chlorohydrin results in decreased expression of TKT protein CTD PMID:26597043 3H-1,2-dithiole-3-thione increases expression EXP 6480464 1, 2-dithiol-3-thione results in increased expression of TKT mRNA CTD PMID:19162173 7,12-dimethyltetraphene decreases expression EXP 6480464 9 more ... CTD PMID:12376462 acetamide decreases expression EXP 6480464 acetamide results in decreased expression of TKT mRNA CTD PMID:31881176 aflatoxin B1 decreases expression ISO RGD:732646 6480464 Aflatoxin B1 results in decreased expression of TKT mRNA CTD PMID:19770486 aflatoxin B1 decreases methylation ISO RGD:732645 6480464 Aflatoxin B1 results in decreased methylation of TKT intron CTD PMID:30157460 all-trans-retinoic acid increases expression ISO RGD:732645 6480464 Tretinoin results in increased expression of TKT mRNA CTD PMID:15894607 , PMID:17218384 all-trans-retinoic acid multiple interactions ISO RGD:732645 6480464 [Tretinoin co-treated with arsenic trioxide] results in increased expression of TKT mRNA CTD PMID:15894607 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of TKT mRNA CTD PMID:16483693 Aroclor 1254 decreases expression ISO RGD:732646 6480464 Chlorodiphenyl 54% Chlorine results in decreased expression of TKT mRNA CTD PMID:23650126 arsane increases expression ISO RGD:732645 6480464 Arsenic results in increased expression of TKT protein CTD PMID:19818359 arsane multiple interactions ISO RGD:732645 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of TKT mRNA CTD PMID:32525701 arsenic atom increases expression ISO RGD:732645 6480464 Arsenic results in increased expression of TKT protein CTD PMID:19818359 arsenic atom multiple interactions ISO RGD:732645 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of TKT mRNA CTD PMID:32525701 arsenous acid multiple interactions ISO RGD:732645 6480464 [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of TKT mRNA, Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to TKT protein] CTD PMID:15894607 , PMID:26598702 astaxanthin multiple interactions ISO RGD:732646 6480464 astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of TKT mRNA] CTD PMID:16964424 atrazine increases expression ISO RGD:732645 6480464 Atrazine results in increased expression of TKT mRNA CTD PMID:22378314 benfotiamine multiple interactions EXP 6480464 [benphothiamine co-treated with Streptozocin] results in increased activity of TKT protein CTD PMID:12592403 benfotiamine multiple interactions ISO RGD:732646 6480464 benphothiamine inhibits the reaction [MAPT protein results in decreased activity of TKT protein] CTD PMID:29860433 benzene decreases expression ISO RGD:732645 6480464 Benzene results in decreased expression of TKT mRNA CTD PMID:20036648 benzo[a]pyrene increases expression ISO RGD:732646 6480464 Benzoapyrene results in increased expression of TKT mRNA CTD PMID:21715664 benzo[a]pyrene affects methylation ISO RGD:732645 6480464 Benzoapyrene affects the methylation of TKT promoter CTD PMID:27901495 benzo[a]pyrene decreases expression ISO RGD:732646 6480464 Benzoapyrene results in decreased expression of TKT mRNA CTD PMID:22228805 benzo[a]pyrene multiple interactions ISO RGD:732646 6480464 AHR protein affects the reaction [Benzoapyrene affects the expression of TKT mRNA] CTD PMID:22228805 benzo[e]pyrene decreases methylation ISO RGD:732645 6480464 benzoepyrene results in decreased methylation of TKT intron CTD PMID:30157460 bisphenol A affects expression ISO RGD:732645 6480464 bisphenol A affects the expression of TKT mRNA CTD PMID:20170705 , PMID:30903817 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of TKT mRNA CTD PMID:30816183 bisphenol A increases expression ISO RGD:732645 6480464 bisphenol A results in increased expression of TKT mRNA CTD PMID:29275510 bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of TKT gene CTD PMID:28505145 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of TKT mRNA CTD PMID:25181051 bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with Estradiol] results in decreased expression of TKT mRNA CTD PMID:26496021 buspirone decreases expression EXP 6480464 Buspirone results in decreased expression of TKT mRNA CTD PMID:24136188 butan-1-ol multiple interactions ISO RGD:732645 6480464 [[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of TKT mRNA CTD PMID:29432896 cadmium atom multiple interactions ISO RGD:732645 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of TKT mRNA CTD PMID:29741670 cadmium dichloride decreases expression EXP 6480464 Cadmium Chloride results in decreased expression of TKT protein CTD PMID:21699967 cadmium dichloride multiple interactions ISO RGD:732645 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of TKT mRNA CTD PMID:29741670 carbamazepine increases expression EXP 6480464 Carbamazepine results in increased expression of TKT mRNA CTD PMID:17381134 carbamazepine decreases expression EXP 6480464 Carbamazepine results in decreased expression of TKT mRNA CTD PMID:17381134 carbon nanotube decreases expression ISO RGD:732646 6480464 Nanotubes more ... CTD PMID:25620056 chloropicrin decreases expression ISO RGD:732645 6480464 chloropicrin results in decreased expression of TKT mRNA CTD PMID:26352163 choline multiple interactions ISO RGD:732646 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of TKT more ... CTD PMID:20938992 cisplatin multiple interactions ISO RGD:732645 6480464 [Cisplatin co-treated with jinfukang] results in increased expression of TKT mRNA CTD PMID:27392435 cobalt dichloride increases expression ISO RGD:732645 6480464 cobaltous chloride results in increased expression of TKT mRNA CTD PMID:17553155 , PMID:19320972 cocaine affects expression ISO RGD:732645 6480464 Cocaine affects the expression of TKT protein CTD PMID:19393250 copper atom affects binding ISO RGD:732645 6480464 TKT protein binds to Copper CTD PMID:15359738 copper(0) affects binding ISO RGD:732645 6480464 TKT protein binds to Copper CTD PMID:15359738 copper(II) chloride increases expression ISO RGD:732645 6480464 cupric chloride results in increased expression of TKT mRNA CTD PMID:17211630 crocidolite asbestos decreases expression ISO RGD:732646 6480464 Asbestos, Crocidolite results in decreased expression of TKT mRNA CTD PMID:19446018 CU-O LINKAGE increases expression ISO RGD:732645 6480464 cupric oxide results in increased expression of TKT protein CTD PMID:25470785 cyclosporin A increases expression ISO RGD:732645 6480464 Cyclosporine results in increased expression of TKT mRNA CTD PMID:25562108 decabromodiphenyl ether increases expression EXP 6480464 decabromobiphenyl ether results in increased expression of TKT mRNA CTD PMID:23914054 diarsenic trioxide multiple interactions ISO RGD:732645 6480464 [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of TKT mRNA, Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to TKT protein] CTD PMID:15894607 , PMID:26598702 diazinon increases methylation ISO RGD:732645 6480464 Diazinon results in increased methylation of TKT gene CTD PMID:22964155 dibutyl phthalate decreases expression ISO RGD:732646 6480464 Dibutyl Phthalate results in decreased expression of TKT mRNA CTD PMID:21266533 dibutyl phthalate decreases expression EXP 6480464 Dibutyl Phthalate results in decreased expression of TKT mRNA CTD PMID:17379624 , PMID:21266533 diuron increases expression EXP 6480464 Diuron results in increased expression of TKT mRNA CTD PMID:21551480 dorsomorphin multiple interactions ISO RGD:732645 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-5-benzo1 more ... CTD PMID:27188386 doxorubicin increases expression ISO RGD:732645 6480464 Doxorubicin results in increased expression of TKT mRNA CTD PMID:29803840 elemental selenium increases expression ISO RGD:732645 6480464 Selenium results in increased expression of TKT mRNA CTD PMID:19244175 endosulfan increases expression EXP 6480464 Endosulfan results in increased expression of TKT mRNA CTD PMID:29391264 enzyme inhibitor multiple interactions ISO RGD:732645 6480464 [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of TKT protein CTD PMID:23301498 felbamate increases expression EXP 6480464 felbamate results in increased expression of TKT mRNA CTD PMID:17381134 finasteride increases expression EXP 6480464 Finasteride results in increased expression of TKT mRNA CTD PMID:24136188 flutamide increases expression EXP 6480464 Flutamide results in increased expression of TKT mRNA CTD PMID:24136188 folic acid multiple interactions ISO RGD:732646 6480464 [1 more ... CTD PMID:20938992 , PMID:22206623 gabapentin increases expression EXP 6480464 gabapentin results in increased expression of TKT mRNA CTD PMID:17381134 genistein decreases expression ISO RGD:732645 6480464 Genistein results in decreased expression of TKT mRNA CTD PMID:16705744 gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of TKT mRNA CTD PMID:22061828 gold atom decreases expression ISO RGD:732646 6480464 Gold analog results in decreased expression of TKT protein CTD PMID:24780912 gold(0) decreases expression ISO RGD:732646 6480464 Gold analog results in decreased expression of TKT protein CTD PMID:24780912 hydroquinone increases expression ISO RGD:732645 6480464 hydroquinone results in increased expression of TKT mRNA CTD PMID:31256213 isotretinoin decreases expression ISO RGD:732645 6480464 Isotretinoin results in decreased expression of TKT mRNA CTD PMID:20436886 L-methionine multiple interactions ISO RGD:732646 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of TKT more ... CTD PMID:20938992 lead(II) chloride increases expression ISO RGD:732645 6480464 lead chloride results in increased expression of TKT mRNA CTD PMID:18654764 levofloxacin decreases expression EXP 6480464 Levofloxacin results in decreased expression of TKT mRNA CTD PMID:24136188 lithium atom increases expression EXP 6480464 Lithium results in increased expression of TKT protein CTD PMID:18296634 lithium hydride increases expression EXP 6480464 Lithium results in increased expression of TKT protein CTD PMID:18296634 mercury dibromide increases expression ISO RGD:732645 6480464 mercuric bromide results in increased expression of TKT mRNA CTD PMID:26272509 mercury dibromide multiple interactions ISO RGD:732645 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-5-benzo1, 3dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-ylbenzamide] results in increased expression of TKT mRNA CTD PMID:27188386 methapyrilene decreases methylation ISO RGD:732645 6480464 Methapyrilene results in decreased methylation of TKT intron CTD PMID:30157460 methapyrilene decreases expression EXP 6480464 Methapyrilene results in decreased expression of TKT protein CTD PMID:30467583 methyl methanesulfonate decreases expression ISO RGD:732645 6480464 Methyl Methanesulfonate results in decreased expression of TKT mRNA CTD PMID:23649840 methylmercury chloride increases expression ISO RGD:732645 6480464 methylmercuric chloride results in increased expression of TKT mRNA CTD PMID:23179753 morphine decreases expression EXP 6480464 Morphine results in decreased expression of TKT protein CTD PMID:23056601 N-methyl-N-nitrosourea increases expression EXP 6480464 Methylnitrosourea results in increased expression of TKT mRNA CTD PMID:16525678 N-nitrosodiethylamine multiple interactions EXP 6480464 [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of TKT mRNA more ... CTD PMID:14656948 more ... N-nitrosodiethylamine increases expression EXP 6480464 Diethylnitrosamine results in increased expression of TKT mRNA CTD PMID:19638242 nefazodone increases expression EXP 6480464 nefazodone results in increased expression of TKT mRNA CTD PMID:24136188 p-chloromercuribenzoic acid increases expression ISO RGD:732645 6480464 p-Chloromercuribenzoic Acid results in increased expression of TKT mRNA CTD PMID:26272509 p-chloromercuribenzoic acid multiple interactions ISO RGD:732645 6480464 [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-5-benzo1, 3dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-ylbenzamide] results in increased expression of TKT mRNA CTD PMID:27188386 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of TKT mRNA CTD PMID:15084756 , PMID:30723492 paracetamol increases expression ISO RGD:732645 6480464 Acetaminophen results in increased expression of TKT mRNA CTD PMID:22230336 paracetamol decreases expression ISO RGD:732645 6480464 Acetaminophen results in decreased expression of TKT mRNA CTD PMID:21420995 paracetamol affects expression ISO RGD:732646 6480464 Acetaminophen affects the expression of TKT mRNA CTD PMID:17562736 PCB138 decreases expression EXP 6480464 2 more ... CTD PMID:21673325 pentachlorophenol increases expression ISO RGD:732646 6480464 Pentachlorophenol results in increased expression of TKT mRNA CTD PMID:23892564 perfluorooctane-1-sulfonic acid decreases expression EXP 6480464 perfluorooctane sulfonic acid results in decreased expression of TKT mRNA CTD PMID:19162173 perfluorooctane-1-sulfonic acid increases expression ISO RGD:732645 6480464 perfluorooctane sulfonic acid results in increased expression of TKT mRNA CTD PMID:27153767 phenethyl caffeate multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of TKT mRNA CTD PMID:20360939 phenobarbital increases expression EXP 6480464 Phenobarbital results in increased expression of TKT mRNA CTD PMID:17381134 , PMID:19162173 phenylmercury acetate increases expression ISO RGD:732645 6480464 Phenylmercuric Acetate results in increased expression of TKT mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO RGD:732645 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-5-benzo1, 3dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-ylbenzamide] results in increased expression of TKT mRNA CTD PMID:27188386 phenytoin increases expression EXP 6480464 Phenytoin results in increased expression of TKT mRNA CTD PMID:17381134 PhIP decreases expression EXP 6480464 2-amino-1-methyl-6-phenylimidazo4, 5-bpyridine results in decreased expression of TKT mRNA CTD PMID:12376462 pirinixic acid multiple interactions ISO RGD:732645 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of TKT mRNA CTD PMID:19710929 pirinixic acid increases expression ISO RGD:732646 6480464 pirinixic acid results in increased expression of TKT mRNA CTD PMID:16221962 pregnenolone 16alpha-carbonitrile increases expression EXP 6480464 Pregnenolone Carbonitrile results in increased expression of TKT mRNA CTD PMID:19162173 quercetin decreases expression EXP 6480464 Quercetin results in decreased expression of TKT protein CTD PMID:18095365 quercetin increases expression ISO RGD:732645 6480464 Quercetin results in increased expression of TKT mRNA CTD PMID:21632981 rac-lactic acid increases expression ISO RGD:732645 6480464 Lactic Acid results in increased expression of TKT mRNA CTD PMID:30851411 resveratrol decreases expression ISO RGD:732646 6480464 resveratrol results in decreased expression of TKT protein CTD PMID:25505154 rotenone increases oxidation EXP 6480464 Rotenone results in increased oxidation of TKT protein CTD PMID:30951809 rotenone decreases expression EXP 6480464 Rotenone results in decreased expression of TKT mRNA CTD PMID:28374803 SB 431542 multiple interactions ISO RGD:732645 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-5-benzo1 more ... CTD PMID:27188386 selenium atom increases expression ISO RGD:732645 6480464 Selenium results in increased expression of TKT mRNA CTD PMID:19244175 silicon dioxide affects secretion ISO RGD:732645 6480464 Silicon Dioxide analog affects the secretion of TKT protein CTD PMID:25895662 sodium arsenate multiple interactions ISO RGD:732645 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of TKT mRNA CTD PMID:32525701 sodium arsenate increases expression ISO RGD:732645 6480464 sodium arsenate results in increased expression of TKT mRNA CTD PMID:12727804 sodium arsenite increases expression ISO RGD:732645 6480464 sodium arsenite results in increased expression of TKT mRNA CTD PMID:25493608 sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of TKT protein CTD PMID:29459688 sodium fluoride decreases expression ISO RGD:732646 6480464 Sodium Fluoride results in decreased expression of TKT protein CTD PMID:28918527 streptozocin multiple interactions EXP 6480464 [benphothiamine co-treated with Streptozocin] results in increased activity of TKT protein CTD PMID:12592403 sunitinib increases expression ISO RGD:732645 6480464 Sunitinib results in increased expression of TKT mRNA CTD PMID:31533062 T-2 toxin affects expression EXP 6480464 T-2 Toxin affects the expression of TKT protein CTD PMID:26141394 tetrachloromethane multiple interactions EXP 6480464 [Olive Oil analog co-treated with Carbon Tetrachloride] affects the expression of TKT protein CTD PMID:25303780 thimerosal decreases expression ISO RGD:732645 6480464 Thimerosal results in decreased expression of TKT mRNA CTD PMID:27188386 titanium dioxide increases expression ISO RGD:732646 6480464 titanium dioxide results in increased expression of TKT mRNA CTD PMID:27760801 trichloroethene decreases expression ISO RGD:732646 6480464 Trichloroethylene results in decreased expression of TKT mRNA CTD PMID:19448997 trovafloxacin decreases expression EXP 6480464 trovafloxacin results in decreased expression of TKT mRNA CTD PMID:24136188 valdecoxib increases expression EXP 6480464 valdecoxib results in increased expression of TKT mRNA CTD PMID:24136188 valproic acid increases expression ISO RGD:732645 6480464 Valproic Acid results in increased expression of TKT mRNA CTD PMID:29154799 valproic acid affects expression ISO RGD:732645 6480464 Valproic Acid affects the expression of TKT mRNA CTD PMID:25979313 valproic acid affects expression ISO RGD:732646 6480464 Valproic Acid affects the expression of TKT mRNA CTD PMID:17292431 vitamin E increases expression ISO RGD:732645 6480464 Vitamin E results in increased expression of TKT mRNA CTD PMID:19244175 zearalenone decreases expression ISO RGD:732646 6480464 Zearalenone results in decreased expression of TKT protein CTD PMID:25058043
