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Gene: Foxa2 (forkhead box A2) Rattus norvegicus
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Symbol: Foxa2
Name: forkhead box A2
Description: Exhibits several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II proximal promoter sequence-specific DNA binding activity; and SMAD binding activity. Involved in positive regulation of transcription by RNA polymerase II and response to insulin. Localizes to the nucleus. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human FOXA2 (forkhead box A2); PARTICIPATES IN forkhead class A signaling pathway; Hedgehog signaling pathway; maturity-onset diabetes of the young pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: forkhead box protein A2; hepatocyte nuclear factor 3 beta; hepatocyte nuclear factor 3, beta; hepatocyte nuclear factor 3-beta; HNF-3-beta; HNF-3B; Hnf3b
Orthologs:
Homo sapiens (human) : FOXA2 (forkhead box A2)  HGNC  Alliance
Mus musculus (house mouse) : Foxa2 (forkhead box A2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Foxa2 (forkhead box A2)
Pan paniscus (bonobo/pygmy chimpanzee) : FOXA2 (forkhead box A2)
Canis lupus familiaris (dog) : FOXA2 (forkhead box A2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Foxa2 (forkhead box A2)
Sus scrofa (pig) : FOXA2 (forkhead box A2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.03142,383,084 - 142,387,493 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03148,793,310 - 148,797,690 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43136,739,009 - 136,743,204 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13136,644,581 - 136,648,777 (-)NCBI
Celera3134,324,023 - 134,328,218 (-)NCBICelera
Cytogenetic Map3q41NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Foxa2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2808
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.