Gene: Mff (mitochondrial fission factor) Rattus norvegicus
Symbol: Mff
Name: mitochondrial fission factor
Description: ENCODES a protein that exhibits GTPase binding; protein-containing complex binding; protein homodimerization activity (ortholog); INVOLVED IN cellular response to hydrogen peroxide; positive regulation of cardiac muscle cell apoptotic process; positive regulation of mitochondrial fission; PARTICIPATES IN mitochondria fission pathway; ASSOCIATED WITH transient cerebral ischemia; Developmental Disabilities (ortholog); ENCEPHALOPATHY DUE TO DEFECTIVE MITOCHONDRIAL AND PEROXISOMAL FISSION 2 (ortholog); FOUND IN mitochondrial membrane; synaptic vesicle; synaptic vesicle membrane; INTERACTS WITH bisphenol A; chloroprene; cocaine
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC301563; MGC112646; mitochondrial fission factor-like; RGD1310230; similar to RIKEN cDNA 5230400G24; uncharacterized protein LOC100911613
Homo sapiens (human) : MFF (mitochondrial fission factor)  HGNC  Alliance
Mus musculus (house mouse) : Mff (mitochondrial fission factor)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mff (mitochondrial fission factor)
Pan paniscus (bonobo/pygmy chimpanzee) : MFF (mitochondrial fission factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mff (mitochondrial fission factor)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0988,490,280 - 88,518,517 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0988,237,923 - 88,266,173 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4982,045,236 - 82,071,135 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1982,226,339 - 82,254,116 (+)NCBI
Celera981,449,284 - 81,477,522 (+)NCBICelera
Cytogenetic Map9q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
More on Mff
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1310230
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2018-10-02
Status: ACTIVE