Slc25a20 (solute carrier family 25 member 20) - Rat Genome Database

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Gene: Slc25a20 (solute carrier family 25 member 20) Rattus norvegicus
Analyze
Symbol: Slc25a20
Name: solute carrier family 25 member 20
RGD ID: 621443
Description: Enables acyl carnitine transmembrane transporter activity. Involved in carnitine transmembrane transport. Predicted to be located in cytosol and mitochondrion. Predicted to be active in mitochondrial envelope. Human ortholog(s) of this gene implicated in carnitine-acylcarnitine translocase deficiency. Orthologous to human SLC25A20 (solute carrier family 25 member 20); PARTICIPATES IN adrenoleukodystrophy pathway; carnitine-acylcarnitine translocase deficiency; fatty acid beta degradation pathway; INTERACTS WITH (R)-carnitine; 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: CAC; CACT; carnitine/acylcarnitine translocase; MGC93269; mitochondrial carnitine/acylcarnitine carrier protein; solute carrier family 25 (carnitine/acylcarnitine translocase), member 20; solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.28109,365,056 - 109,386,512 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8109,365,002 - 109,386,512 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8114,983,063 - 115,004,624 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.08113,182,398 - 113,203,797 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.08111,025,038 - 111,046,601 (+)NCBIRnor_WKY
Rnor_6.08117,455,308 - 117,476,762 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8117,455,262 - 117,476,734 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08116,800,146 - 116,821,558 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48113,715,211 - 113,737,063 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18113,734,665 - 113,756,518 (+)NCBI
Celera8108,660,802 - 108,681,758 (+)NCBICelera
Cytogenetic Map8q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(R)-carnitine  (EXP)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrotoluene  (EXP)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4-hydroxyphenyl retinamide  (ISO)
acetamide  (EXP)
aconitine  (EXP)
aflatoxin B1  (EXP)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
ampicillin  (EXP)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
buspirone  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
cefalotin  (EXP)
cefazolin  (EXP)
cefonicid  (EXP)
chloroacetaldehyde  (ISO)
chromium(6+)  (ISO)
cidofovir anhydrous  (ISO)
ciprofibrate  (EXP)
cisplatin  (ISO)
clodronic acid  (ISO)
clofibrate  (EXP,ISO)
Clofop  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (EXP,ISO)
dexamethasone  (ISO)
dibutyl phthalate  (EXP)
dichloroacetic acid  (ISO)
dicrotophos  (ISO)
dioxygen  (ISO)
dithioerythritol  (EXP,ISO)
dorsomorphin  (ISO)
doxorubicin  (EXP)
epoxiconazole  (ISO)
farnesol  (ISO)
fenofibrate  (EXP,ISO)
finasteride  (EXP)
flutamide  (ISO)
folic acid  (ISO)
glutathione  (ISO)
GW 4064  (ISO)
GW 7647  (ISO)
hexadecanoic acid  (EXP)
hydrogen peroxide  (EXP)
ibuprofen  (EXP)
ifosfamide  (ISO)
isoprenaline  (EXP)
L-cysteine  (EXP)
lamivudine  (ISO)
leflunomide  (EXP)
lenvatinib  (EXP,ISO)
lipopolysaccharide  (ISO)
mercury dichloride  (ISO)
metformin  (EXP)
methapyrilene  (EXP,ISO)
methylmercury chloride  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
Muraglitazar  (EXP)
N,N-diethyl-m-toluamide  (EXP)
N-acetyl-L-cysteine  (EXP,ISO)
nefazodone  (EXP)
nickel atom  (ISO)
nimesulide  (EXP)
O-acetyl-L-carnitine  (EXP)
ochratoxin A  (EXP)
oleic acid  (EXP,ISO)
paracetamol  (ISO)
PCB138  (EXP)
perfluorododecanoic acid  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP,ISO)
permethrin  (EXP)
phenobarbital  (EXP)
phenylmercury acetate  (ISO)
piperacillin  (EXP)
pirinixic acid  (EXP,ISO)
potassium chromate  (ISO)
pravastatin  (ISO)
propiconazole  (ISO)
Pyridostigmine bromide  (EXP)
quercetin  (ISO)
rotenone  (EXP,ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
sodium arsenite  (EXP,ISO)
streptozocin  (EXP)
sunitinib  (ISO)
Tesaglitazar  (EXP)
testosterone  (ISO)
tetrachloroethene  (ISO)
tetracycline  (ISO)
thalidomide  (ISO)
thapsigargin  (ISO)
thioacetamide  (EXP)
tributylstannane  (ISO)
trichloroethene  (ISO)
trichostatin A  (ISO)
troglitazone  (EXP)
tunicamycin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
zaragozic acid A  (EXP,ISO)
zidovudine  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Bacterial overexpression, purification, and reconstitution of the carnitine/acylcarnitine carrier from rat liver mitochondria. Indiveri C, etal., Biochem Biophys Res Commun. 1998 Aug 28;249(3):589-94. doi: 10.1006/bbrc.1998.9197.
4. The mitochondrial carnitine carrier protein: cDNA cloning, primary structure and comparison with other mitochondrial transport proteins. Indiveri C, etal., Biochem J 1997 Feb 1;321 ( Pt 3):713-9.
5. Site-directed mutagenesis and chemical modification of the six native cysteine residues of the rat mitochondrial carnitine carrier: implications for the role of cysteine-136. Indiveri C, etal., Biochemistry 2002 Jul 9;41(27):8649-56.
6. Identification and purification of the carnitine carrier from rat liver mitochondria. Indiveri C, etal., Biochim Biophys Acta. 1990 Oct 24;1020(1):81-6.
7. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
8. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
9. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
10. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
11. GOA pipeline RGD automated data pipeline
12. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
13. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
14. Structural insight into function and regulation of carnitine palmitoyltransferase. Rufer AC, etal., Cell Mol Life Sci. 2009 Aug;66(15):2489-501. Epub 2009 May 9.
15. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:9399886   PMID:12865426   PMID:15757911   PMID:18614015   PMID:20833797   PMID:22365929   PMID:24898781   PMID:27864727   PMID:27996060   PMID:28438511  


Genomics

Comparative Map Data
Slc25a20
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.28109,365,056 - 109,386,512 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8109,365,002 - 109,386,512 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8114,983,063 - 115,004,624 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.08113,182,398 - 113,203,797 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.08111,025,038 - 111,046,601 (+)NCBIRnor_WKY
Rnor_6.08117,455,308 - 117,476,762 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8117,455,262 - 117,476,734 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08116,800,146 - 116,821,558 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48113,715,211 - 113,737,063 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18113,734,665 - 113,756,518 (+)NCBI
Celera8108,660,802 - 108,681,758 (+)NCBICelera
Cytogenetic Map8q32NCBI
SLC25A20
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38348,856,926 - 48,898,882 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl348,856,926 - 48,898,904 (-)EnsemblGRCh38hg38GRCh38
GRCh37348,894,359 - 48,936,315 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36348,869,368 - 48,911,333 (-)NCBINCBI36Build 36hg18NCBI36
Build 34348,869,368 - 48,911,333NCBI
Celera348,850,594 - 48,892,435 (-)NCBICelera
Cytogenetic Map3p21.31NCBI
HuRef348,952,554 - 48,994,892 (-)NCBIHuRef
CHM1_1348,846,459 - 48,888,551 (-)NCBICHM1_1
T2T-CHM13v2.0348,885,896 - 48,927,887 (-)NCBIT2T-CHM13v2.0
Slc25a20
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399108,539,335 - 108,561,841 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9108,539,287 - 108,561,840 (+)EnsemblGRCm39 Ensembl
GRCm389108,662,136 - 108,684,642 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9108,662,088 - 108,684,641 (+)EnsemblGRCm38mm10GRCm38
MGSCv379108,564,429 - 108,586,972 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369108,519,502 - 108,542,045 (+)NCBIMGSCv36mm8
Celera9108,275,033 - 108,292,081 (+)NCBICelera
Cytogenetic Map9F2NCBI
Slc25a20
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955532902,937 - 921,174 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955532902,937 - 933,675 (-)NCBIChiLan1.0ChiLan1.0
SLC25A20
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1349,863,259 - 49,901,839 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl349,863,259 - 49,901,839 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0348,782,960 - 48,824,616 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
SLC25A20
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12040,244,222 - 40,271,100 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2040,244,229 - 40,270,433 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2040,161,526 - 40,188,235 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02040,601,674 - 40,627,761 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2040,601,718 - 40,755,942 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12039,967,112 - 39,993,969 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02040,370,902 - 40,397,702 (+)NCBIUNSW_CanFamBas_1.0
Slc25a20
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560263,846,541 - 63,871,412 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936529606,804 - 631,991 (-)EnsemblSpeTri2.0
SpeTri2.0NW_004936529607,035 - 631,872 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC25A20
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1331,523,821 - 31,553,286 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11331,523,820 - 31,553,289 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21334,777,394 - 34,804,819 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SLC25A20
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12210,261,772 - 10,300,878 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2210,261,634 - 10,300,778 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041156,788,381 - 156,827,761 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc25a20
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247302,832,233 - 2,860,796 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247302,833,785 - 2,860,711 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Slc25a20
111 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:110
Count of miRNA genes:83
Interacting mature miRNAs:100
Transcripts:ENSRNOT00000027520
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)88462195110921472Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)810378157112202585Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)840952565123900184Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)846531639119088624Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)846531639119088624Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)846531639119088624Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)846531639119088624Rat
2303171Bp331Blood pressure QTL 3315.570.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)861290298119084929Rat
631653Bp125Blood pressure QTL 1253.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)866142385111142385Rat
631210Bw3Body weight QTL35.9mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)869349194112783834Rat
1300171Bp184Blood pressure QTL 1843.66arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)870513503118219066Rat
8694446Bw170Body weight QTL 17012.070.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)871888757116888757Rat
9590292Uminl3Urine mineral level QTL 33.620.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)871888757116888757Rat
8694200Abfw4Abdominal fat weight QTL 49.070.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)871888757116888757Rat
8694392Bw161Body weight QTL 1618.060.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)871888757116888757Rat
1549909Stresp11Stress response QTL 116.830.0019stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)873473045118473045Rat
2300181Bmd55Bone mineral density QTL 555.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)876468691121468691Rat
61437Cia6Collagen induced arthritis QTL 6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)882460758122812818Rat
2313400Anxrr25Anxiety related response QTL 25aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)889265192114019816Rat
738011Anxrr9Anxiety related response QTL 96.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)893535351123900184Rat
1358893Bp263Blood pressure QTL 2635.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)893965141123900184Rat
1358903Bp252Blood pressure QTL 25270.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)893965141123900184Rat
738014Anxrr15Anxiety related response QTL 153.60.005locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)895718998123900184Rat
2300182Bmd56Bone mineral density QTL 565.4femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)895718998123900184Rat
724539Cm19Cardiac mass QTL 192.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)8100149864120994388Rat

Markers in Region
RH143998  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28109,380,452 - 109,380,561 (+)MAPPERmRatBN7.2
Rnor_6.08117,470,703 - 117,470,811NCBIRnor6.0
Rnor_5.08116,815,541 - 116,815,649UniSTSRnor5.0
RGSC_v3.48113,731,004 - 113,731,112UniSTSRGSC3.4
Celera8108,675,780 - 108,675,888UniSTS
RH 3.4 Map81115.1UniSTS
Cytogenetic Map8q32UniSTS
BE106540  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28109,385,003 - 109,385,727 (+)MAPPERmRatBN7.2
Rnor_6.08117,475,254 - 117,475,977NCBIRnor6.0
Rnor_5.08116,820,050 - 116,820,773UniSTSRnor5.0
RGSC_v3.48113,735,555 - 113,736,278UniSTSRGSC3.4
Celera8108,680,274 - 108,680,973UniSTS
RH 3.4 Map81115.7UniSTS
Cytogenetic Map8q32UniSTS
RH136924  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28109,386,242 - 109,386,440 (+)MAPPERmRatBN7.2
Rnor_6.08117,476,493 - 117,476,690NCBIRnor6.0
Rnor_5.08116,821,289 - 116,821,486UniSTSRnor5.0
RGSC_v3.48113,736,794 - 113,736,991UniSTSRGSC3.4
Celera8108,681,489 - 108,681,686UniSTS
Cytogenetic Map8q32UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000027520   ⟹   ENSRNOP00000027520
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl8109,365,002 - 109,386,512 (+)Ensembl
Rnor_6.0 Ensembl8117,455,262 - 117,476,734 (+)Ensembl
RefSeq Acc Id: NM_053965   ⟹   NP_446417
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.28109,365,056 - 109,386,512 (+)NCBI
Rnor_6.08117,455,308 - 117,476,762 (+)NCBI
Rnor_5.08116,800,146 - 116,821,558 (+)NCBI
RGSC_v3.48113,715,211 - 113,737,063 (+)RGD
Celera8108,660,802 - 108,681,758 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_446417 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH81749 (Get FASTA)   NCBI Sequence Viewer  
  CAA66410 (Get FASTA)   NCBI Sequence Viewer  
  EDL77151 (Get FASTA)   NCBI Sequence Viewer  
  EDL77152 (Get FASTA)   NCBI Sequence Viewer  
  P97521 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_446417   ⟸   NM_053965
- UniProtKB: Q66HP8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000027520   ⟸   ENSRNOT00000027520

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P97521-F1-model_v2 AlphaFold P97521 1-301 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696313
Promoter ID:EPDNEW_R6838
Type:initiation region
Name:Slc25a20_1
Description:solute carrier family 25 member 20
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R6839  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.08117,455,286 - 117,455,346EPDNEW
RGD ID:13696314
Promoter ID:EPDNEW_R6839
Type:initiation region
Name:Slc25a20_2
Description:solute carrier family 25 member 20
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R6838  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.08117,455,388 - 117,455,448EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621443 AgrOrtholog
BioCyc Gene G2FUF-29121 BioCyc
Ensembl Genes ENSRNOG00000020288 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000027520 ENTREZGENE
  ENSRNOP00000027520.2 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000027520 ENTREZGENE
  ENSRNOT00000027520.5 UniProtKB/TrEMBL
Gene3D-CATH 1.50.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7134670 IMAGE-MGC_LOAD
InterPro Mitochondrial_sb/sol_carrier UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Mt_carrier_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:117035 UniProtKB/TrEMBL
MGC_CLONE MGC:93269 IMAGE-MGC_LOAD
NCBI Gene 117035 ENTREZGENE
Pfam Mito_carr UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Slc25a20 PhenoGen
PROSITE SOLCAR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF103506 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt MCAT_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q66HP8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-09 Slc25a20  solute carrier family 25 member 20  Slc25a20  solute carrier family 25 (carnitine/acylcarnitine translocase), member 20  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-19 Slc25a20  solute carrier family 25 (carnitine/acylcarnitine translocase), member 20  Slc25a20  solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Slc25a20  solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20    solute carrier family 25 (carnitine/acylcarnitine translocase), member 20  Name updated 1299863 APPROVED
2005-01-20 Slc25a20  solute carrier family 25 (carnitine/acylcarnitine translocase), member 20      Name updated 1299863 APPROVED
2002-08-07 Slc25a20  solute carrier family 25 (carnitine/acylcarnitine translocase), member 20      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_domains site-directed mutagenesis show that none of the native cysteines is essential for the transport mechanism 730058
gene_product member of the mitochondrial carrier family 730031
gene_protein protein contains 301 aa residues 730031