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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621443
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc25a20
Name: solute carrier family 25 member 20
Acc ID: CHEBI:124991
Term: cefalotin
Definition: A semisynthetic, first-generation cephalosporin antibiotic with acetoxymethyl and (2-thienylacetyl)nitrilo moieties at positions 3 and 7, respectively, of the core structure. Administered parenterally during surgery and to treat a wide spectrum of blood infections.
Chemical ID: MESH:D002512
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTDCephalothin binds to and results in decreased activity of SLC25A20 protein, Cephalothin inhibits the reaction [SLC25A20 protein results in increased transport of Carnitine]

PMID:18452908
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.