Gene: Prkg1 (protein kinase, cGMP-dependent, type 1) Rattus norvegicus
Symbol: Prkg1
Name: protein kinase, cGMP-dependent, type 1
Description: ENCODES a protein that exhibits mitogen-activated protein kinase p38 binding; protein homodimerization activity; calcium channel regulator activity (ortholog); INVOLVED IN brain development; cell growth involved in cardiac muscle cell development; cerebellum development; PARTICIPATES IN eicosanoid signaling pathway; long term depression; ASSOCIATED WITH Diabetes Mellitus, Experimental; Erectile Dysfunction; Hypertension; FOUND IN acrosomal vesicle; cytosol; Golgi apparatus; INTERACTS WITH 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one; 7-NITROINDAZOLE; 8-(4-chlorophenylthio)-cGMP
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: cGk1; cGMP dependent protein kinase type 1; cGMP dependent protein kinase type1; cGMP-dependent protein kinase 1; LOC365449; Pkgi; Prkg1_mapped; protein kinase, cGMP-dependent, type 1 (mapped); Protein kinase, cGMP-dependent, type I
Homo sapiens (human) : PRKG1 (protein kinase, cGMP-dependent, type I)  HGNC  AGR
Mus musculus (house mouse) : Prkg1 (protein kinase, cGMP-dependent, type I)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Prkg1 (protein kinase, cGMP-dependent, type I)
Pan paniscus (bonobo/pygmy chimpanzee) : PRKG1 (protein kinase, cGMP-dependent, type I)
Canis lupus familiaris (dog) : PRKG1 (protein kinase, cGMP-dependent, type I)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Prkg1 (protein kinase, cGMP-dependent, type I)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01248,982,039 - 250,300,952 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01256,221,067 - 257,537,289 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41234,420,597 - 235,765,375 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11235,515,049 - 235,845,833 (-)NCBI
Celera1225,545,145 - 226,760,176 (-)NCBICelera
Cytogenetic Map1q52NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Prkg1
AGR Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1587390
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2017-10-10
Status: ACTIVE