Gene: Prkg1 (protein kinase, cGMP-dependent, type 1) Rattus norvegicus
Symbol: Prkg1
Name: protein kinase, cGMP-dependent, type 1
Description: ENCODES a protein that exhibits mitogen-activated protein kinase p38 binding; protein homodimerization activity; calcium channel regulator activity (ortholog); INVOLVED IN brain development; cell growth involved in cardiac muscle cell development; cerebellum development; PARTICIPATES IN eicosanoid signaling pathway; long term depression; ASSOCIATED WITH allergic rhinitis; Experimental Diabetes Mellitus; hypertension; FOUND IN acrosomal vesicle; cytosol; Golgi apparatus; INTERACTS WITH 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one; 7-NITROINDAZOLE; 8-(4-chlorophenylthio)-cGMP
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: cGk1; cGMP dependent protein kinase type 1; cGMP dependent protein kinase type1; cGMP-dependent protein kinase 1; LOC365449; Pkgi; Prkg1_mapped; protein kinase, cGMP-dependent, type 1 (mapped); Protein kinase, cGMP-dependent, type I
Homo sapiens (human) : PRKG1 (protein kinase cGMP-dependent 1)  HGNC  Alliance
Mus musculus (house mouse) : Prkg1 (protein kinase, cGMP-dependent, type I)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Prkg1 (protein kinase cGMP-dependent 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PRKG1 (protein kinase cGMP-dependent 1)
Canis lupus familiaris (dog) : PRKG1 (protein kinase, cGMP-dependent, type I)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Prkg1 (protein kinase cGMP-dependent 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01248,982,039 - 250,300,952 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01256,221,067 - 257,537,289 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41234,420,597 - 235,765,375 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11235,515,049 - 235,845,833 (-)NCBI
Celera1225,545,145 - 226,760,176 (-)NCBICelera
Cytogenetic Map1q52NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Prkg1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1587390
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2018-06-05
Status: ACTIVE