(RS)-coclaurine multiple interactions ISO RGD:1550381 6480464 [Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in decreased expression of BHMT mRNA CTD PMID:28843594 (RS)-norcoclaurine multiple interactions ISO RGD:1550381 6480464 [Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in decreased expression of BHMT mRNA CTD PMID:28843594 (S)-coclaurine multiple interactions ISO RGD:1550381 6480464 [Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in decreased expression of BHMT mRNA CTD PMID:28843594 1-(3-(trifluoromethyl)phenyl)piperazine decreases expression EXP 6480464 1-(3-trifluoromethylphenyl)piperazine results in decreased expression of BHMT mRNA CTD PMID:26821219 1-benzylpiperazine decreases expression EXP 6480464 N-benzylpiperazine results in decreased expression of BHMT mRNA CTD PMID:26821219 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of BHMT mRNA CTD PMID:11752688 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:1550381 6480464 Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to BHMT gene] CTD PMID:28213091 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:1550381 6480464 Tetrachlorodibenzodioxin results in decreased expression of BHMT mRNA CTD PMID:28213091 , PMID:28922406 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:1550381 6480464 Tetrachlorodibenzodioxin affects the expression of BHMT mRNA CTD PMID:21570461 , PMID:26377647 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of BHMT mRNA CTD PMID:16054898 , PMID:18465118 2,4-dinitrotoluene affects expression EXP 6480464 2, 4-dinitrotoluene affects the expression of BHMT mRNA CTD PMID:21346803 2,6-dinitrotoluene affects expression EXP 6480464 2, 6-dinitrotoluene affects the expression of BHMT mRNA CTD PMID:21346803 2-nitrofluorene decreases expression EXP 6480464 2-nitrofluorene results in decreased expression of BHMT mRNA CTD PMID:14600272 3-chloropropane-1,2-diol decreases expression EXP 6480464 alpha-Chlorohydrin analog results in decreased expression of BHMT protein, alpha-Chlorohydrin results in decreased expression of BHMT protein CTD PMID:26597043 3H-1,2-dithiole-3-thione increases expression ISO RGD:1550381 6480464 1, 2-dithiol-3-thione results in increased expression of BHMT mRNA CTD PMID:15302862 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one decreases expression EXP 6480464 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of BHMT mRNA CTD PMID:14600272 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of BHMT mRNA CTD PMID:24780913 , PMID:25825206 acrylamide decreases expression EXP 6480464 Acrylamide results in decreased expression of BHMT mRNA CTD PMID:28959563 aflatoxin B1 decreases expression EXP 6480464 Aflatoxin B1 results in decreased expression of BHMT mRNA CTD PMID:14600272 aflatoxin B1 decreases expression ISO RGD:1346951 6480464 Aflatoxin B1 results in decreased expression of BHMT mRNA CTD PMID:21641981 , PMID:27153756 all-trans-retinoic acid decreases expression ISO RGD:1346951 6480464 Tretinoin results in decreased expression of BHMT mRNA, Tretinoin results in decreased expression of BHMT protein CTD PMID:19960509 amiodarone affects expression EXP 6480464 Amiodarone affects the expression of BHMT mRNA CTD PMID:18355885 amitriptyline affects expression EXP 6480464 Amitriptyline affects the expression of BHMT mRNA CTD PMID:18355885 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of BHMT mRNA CTD PMID:16483693 andrographolide multiple interactions ISO RGD:1550381 6480464 [andrographolide co-treated with beta-Naphthoflavone] results in decreased expression of BHMT mRNA CTD PMID:19737545 arsane decreases expression ISO RGD:1346951 6480464 Arsenic results in decreased expression of BHMT mRNA CTD PMID:18487201 arsenic atom decreases expression ISO RGD:1346951 6480464 Arsenic results in decreased expression of BHMT mRNA CTD PMID:18487201 arsenite(3-) increases methylation ISO RGD:1346951 6480464 arsenite results in increased methylation of BHMT promoter CTD PMID:23974009 benzo[a]pyrene decreases expression ISO RGD:1550381 6480464 Benzo(a)pyrene results in decreased expression of BHMT mRNA CTD PMID:19770486 benzo[a]pyrene decreases expression ISO RGD:1346951 6480464 Benzo(a)pyrene results in decreased expression of BHMT mRNA CTD PMID:21632981 , PMID:26238291 benzo[b]fluoranthene decreases expression ISO RGD:1550381 6480464 benzo(b)fluoranthene results in decreased expression of BHMT mRNA CTD PMID:26377693 beta-naphthoflavone multiple interactions ISO RGD:1550381 6480464 [andrographolide co-treated with beta-Naphthoflavone] results in decreased expression of BHMT mRNA CTD PMID:19737545 bis(2-ethylhexyl) phthalate decreases expression ISO RGD:1346951 6480464 Diethylhexyl Phthalate results in decreased expression of BHMT mRNA CTD PMID:31163220 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of BHMT mRNA CTD PMID:25181051 bisphenol A affects expression ISO RGD:1346951 6480464 bisphenol A affects the expression of BHMT mRNA CTD PMID:30903817 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of BHMT mRNA CTD PMID:30903817 bromobenzene decreases expression EXP 6480464 bromobenzene results in decreased expression of BHMT mRNA CTD PMID:12628495 bromobenzene increases expression EXP 6480464 bromobenzene results in increased expression of BHMT mRNA CTD PMID:15056800 buta-1,3-diene decreases expression ISO RGD:1550381 6480464 1, 3-butadiene results in decreased expression of BHMT mRNA CTD PMID:29038090 cadmium dichloride decreases expression EXP 6480464 Cadmium Chloride results in decreased expression of BHMT mRNA CTD PMID:25993096 caffeine multiple interactions ISO RGD:1550381 6480464 [Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in decreased expression of BHMT mRNA CTD PMID:28843594 choline multiple interactions ISO RGD:1550381 6480464 [Choline deficiency co-treated with Folic Acid deficiency co-treated with Methionine deficiency] results in decreased expression of BHMT mRNA, [Choline deficiency co-treated with Folic Acid deficiency] affects the expression of BHMT mRNA CTD PMID:23439872 , PMID:29127188 ciglitazone multiple interactions ISO RGD:1346951 6480464 [ciglitazone binds to PPARG protein alternative form] which results in increased expression of BHMT mRNA CTD PMID:16197558 ciguatoxin CTX1B affects expression ISO RGD:1550381 6480464 Ciguatoxins affects the expression of BHMT mRNA CTD PMID:18353800 cisplatin increases expression EXP 6480464 Cisplatin results in increased expression of BHMT protein CTD PMID:22023808 clofibrate decreases expression EXP 6480464 Clofibrate results in decreased expression of BHMT mRNA CTD PMID:12851107 clomipramine affects expression EXP 6480464 Clomipramine affects the expression of BHMT mRNA CTD PMID:18355885 copper atom decreases expression EXP 6480464 Copper results in decreased expression of BHMT mRNA CTD PMID:22465980 copper(0) decreases expression EXP 6480464 Copper results in decreased expression of BHMT mRNA CTD PMID:22465980 copper(II) sulfate decreases expression ISO RGD:1346951 6480464 Copper Sulfate results in decreased expression of BHMT mRNA CTD PMID:19549813 coumarin decreases expression EXP 6480464 coumarin results in decreased expression of BHMT mRNA CTD PMID:18480146 coumarin affects expression EXP 6480464 coumarin affects the expression of BHMT mRNA CTD PMID:16963487 cyclosporin A decreases expression ISO RGD:1346951 6480464 Cyclosporine results in decreased expression of BHMT mRNA CTD PMID:20106945 more ... diethyl maleate decreases expression EXP 6480464 diethyl maleate results in decreased expression of BHMT mRNA CTD PMID:21161181 diethylstilbestrol increases expression ISO RGD:1550381 6480464 Diethylstilbestrol results in increased expression of BHMT mRNA CTD PMID:19665456 diethylstilbestrol multiple interactions ISO RGD:1550381 6480464 sodium arsenite promotes the reaction [Diethylstilbestrol results in increased expression of BHMT mRNA] CTD PMID:19665456 dorsomorphin multiple interactions ISO RGD:1346951 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BHMT mRNA CTD PMID:27188386 endosulfan decreases expression EXP 6480464 Endosulfan results in decreased expression of BHMT mRNA CTD PMID:29391264 ethanol increases expression EXP 6480464 Ethanol results in increased expression of BHMT mRNA CTD PMID:16098508 , PMID:17920746 folic acid multiple interactions ISO RGD:1550381 6480464 [Choline deficiency co-treated with Folic Acid deficiency co-treated with Methionine deficiency] results in decreased expression of BHMT mRNA, [Choline deficiency co-treated with Folic Acid deficiency] affects the expression of BHMT mRNA CTD PMID:23439872 , PMID:29127188 fumonisin B1 decreases expression ISO RGD:1550381 6480464 fumonisin B1 results in decreased expression of BHMT mRNA CTD PMID:16221962 furan affects binding EXP 6480464 furan binds to BHMT protein CTD PMID:22240984 furan increases methylation EXP 6480464 furan results in increased methylation of BHMT gene CTD PMID:22079235 glafenine decreases expression EXP 6480464 Glafenine results in decreased expression of BHMT mRNA CTD PMID:24136188 glycine betaine increases metabolic processing ISO RGD:1346951 6480464 BHMT protein results in increased metabolism of Betaine CTD PMID:18230605 imipramine affects expression EXP 6480464 Imipramine affects the expression of BHMT mRNA CTD PMID:18355885 ketoconazole affects expression EXP 6480464 Ketoconazole affects the expression of BHMT mRNA CTD PMID:18355885 L-methionine multiple interactions ISO RGD:1346951 6480464 Methionine inhibits the reaction [BHMT protein results in increased metabolism of Vitamin U] CTD PMID:18230605 L-methionine multiple interactions ISO RGD:1550381 6480464 [Choline deficiency co-treated with Folic Acid deficiency co-treated with Methionine deficiency] results in decreased expression of BHMT mRNA CTD PMID:29127188 lead diacetate decreases expression EXP 6480464 lead acetate results in decreased expression of BHMT mRNA CTD PMID:22641619 mercury dichloride multiple interactions ISO RGD:1550381 6480464 [Trichloroethylene co-treated with Mercuric Chloride] results in increased expression of BHMT mRNA CTD PMID:21084432 methapyrilene decreases expression EXP 6480464 Methapyrilene results in decreased expression of BHMT mRNA CTD PMID:16393664 mono(2-ethylhexyl) phthalate decreases expression ISO RGD:1550381 6480464 mono-(2-ethylhexyl)phthalate results in decreased expression of BHMT mRNA CTD PMID:22401849 N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of BHMT mRNA CTD PMID:28943392 N-nitrosodiethylamine multiple interactions ISO RGD:1550381 6480464 [Diethylnitrosamine co-treated with Carbon Tetrachloride] results in decreased expression of BHMT mRNA CTD PMID:29127188 N-nitrosodimethylamine decreases expression EXP 6480464 Dimethylnitrosamine results in decreased expression of BHMT mRNA CTD PMID:14600272 N-nitrosomorpholine affects expression EXP 6480464 N-nitrosomorpholine affects the expression of BHMT protein CTD PMID:19716841 nefazodone decreases expression EXP 6480464 nefazodone results in decreased expression of BHMT mRNA CTD PMID:24136188 nimesulide decreases expression EXP 6480464 nimesulide results in decreased expression of BHMT mRNA CTD PMID:24136188 ochratoxin A decreases expression EXP 6480464 ochratoxin A results in decreased expression of BHMT mRNA CTD PMID:12700408 paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of BHMT mRNA CTD PMID:17202762 paracetamol multiple interactions ISO RGD:1550381 6480464 PANX1 gene mutant form inhibits the reaction [Acetaminophen results in decreased expression of BHMT mRNA] CTD PMID:29246445 paracetamol decreases expression ISO RGD:1550381 6480464 Acetaminophen results in decreased expression of BHMT mRNA CTD PMID:29246445 perfluorooctanoic acid affects expression ISO RGD:1550381 6480464 perfluorooctanoic acid affects the expression of BHMT mRNA CTD PMID:18281256 perfluorooctanoic acid decreases expression EXP 6480464 perfluorooctanoic acid results in decreased expression of BHMT mRNA CTD PMID:19162173 phorbol 13-acetate 12-myristate multiple interactions ISO RGD:1550381 6480464 [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of BHMT mRNA CTD PMID:16368122 piperonyl butoxide decreases expression EXP 6480464 Piperonyl Butoxide results in decreased expression of BHMT mRNA CTD PMID:22484513 pirinixic acid decreases expression ISO RGD:1550381 6480464 pirinixic acid results in decreased expression of BHMT mRNA CTD PMID:16221962 pirinixic acid decreases expression EXP 6480464 pirinixic acid results in decreased expression of BHMT mRNA CTD PMID:19162173 , PMID:22484513 pirinixic acid multiple interactions ISO RGD:1346951 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of BHMT mRNA CTD PMID:19710929 potassium dichromate decreases expression ISO RGD:1550381 6480464 Potassium Dichromate results in decreased expression of BHMT mRNA CTD PMID:23608068 pregnenolone 16alpha-carbonitrile increases expression ISO RGD:1550381 6480464 Pregnenolone Carbonitrile results in increased expression of BHMT mRNA CTD PMID:28903501 quercetin increases expression ISO RGD:1550381 6480464 Quercetin results in increased expression of BHMT mRNA CTD PMID:16455785 quercetin decreases expression ISO RGD:1346951 6480464 Quercetin results in decreased expression of BHMT mRNA CTD PMID:21632981 quercetin decreases expression EXP 6480464 Quercetin results in decreased expression of BHMT mRNA CTD PMID:21565894 SB 431542 multiple interactions ISO RGD:1346951 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BHMT mRNA CTD PMID:27188386 sodium arsenite multiple interactions ISO RGD:1550381 6480464 [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of BHMT mRNA, sodium arsenite promotes the reaction [Diethylstilbestrol results in increased expression of BHMT mRNA] CTD PMID:16368122 , PMID:19665456 sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of BHMT protein CTD PMID:29459688 sodium arsenite decreases expression ISO RGD:1550381 6480464 sodium arsenite results in decreased expression of BHMT mRNA CTD PMID:15276417 more ... sodium arsenite affects expression ISO RGD:1550381 6480464 sodium arsenite affects the expression of BHMT mRNA CTD PMID:16507464 sodium dichromate decreases expression EXP 6480464 sodium bichromate results in decreased expression of BHMT mRNA CTD PMID:25993096 streptozocin increases activity EXP 6480464 Streptozocin results in increased activity of BHMT protein CTD PMID:16835399 streptozocin multiple interactions ISO RGD:1550381 6480464 [Streptozocin co-treated with Dietary Fats] affects the expression of BHMT mRNA CTD PMID:29127188 streptozocin increases expression EXP 6480464 Streptozocin results in increased expression of BHMT mRNA CTD PMID:16835399 sunitinib increases expression ISO RGD:1346951 6480464 Sunitinib results in increased expression of BHMT mRNA CTD PMID:31533062 tert-butyl hydroperoxide increases methylation ISO RGD:1346951 6480464 tert-Butylhydroperoxide results in increased methylation of BHMT gene CTD PMID:27509014 tert-butyl hydroperoxide decreases expression ISO RGD:1346951 6480464 tert-Butylhydroperoxide results in decreased expression of BHMT mRNA CTD PMID:27509014 tetrachloromethane decreases expression ISO RGD:1550381 6480464 Carbon Tetrachloride results in decreased expression of BHMT mRNA CTD PMID:27339419 tetrachloromethane multiple interactions ISO RGD:1550381 6480464 [Diethylnitrosamine co-treated with Carbon Tetrachloride] results in decreased expression of BHMT mRNA CTD PMID:29127188 tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of BHMT mRNA CTD PMID:31150632 thioacetamide multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of BHMT mRNA CTD PMID:28943392 trichloroethene multiple interactions ISO RGD:1550381 6480464 [Trichloroethylene co-treated with Mercuric Chloride] results in increased expression of BHMT mRNA CTD PMID:21084432 trichloroethene increases expression ISO RGD:1550381 6480464 Trichloroethylene results in increased expression of BHMT mRNA CTD PMID:19254012 trichostatin A increases expression ISO RGD:1346951 6480464 trichostatin A results in increased expression of BHMT mRNA CTD PMID:24935251 tris(2-butoxyethyl) phosphate affects expression ISO RGD:1346951 6480464 tris(2-butoxyethyl) phosphate affects the expression of BHMT mRNA CTD PMID:29024780 urethane increases expression ISO RGD:1346951 6480464 Urethane results in increased expression of BHMT mRNA CTD PMID:28818685 valdecoxib decreases expression EXP 6480464 valdecoxib results in decreased expression of BHMT mRNA CTD PMID:24136188 valproic acid affects expression ISO RGD:1346951 6480464 Valproic Acid affects the expression of BHMT mRNA CTD PMID:25979313 valproic acid multiple interactions ISO RGD:1346951 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BHMT mRNA CTD PMID:27188386 valproic acid increases expression ISO RGD:1346951 6480464 Valproic Acid results in increased expression of BHMT mRNA CTD PMID:23179753 more ... vancomycin increases expression ISO RGD:1550381 6480464 Vancomycin results in increased expression of BHMT mRNA CTD PMID:18930951 vinclozolin increases expression EXP 6480464 vinclozolin results in increased expression of BHMT mRNA CTD PMID:22570695 yohimbine multiple interactions ISO RGD:1550381 6480464 [Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in decreased expression of BHMT mRNA CTD PMID:28843594 zinc atom increases expression EXP 6480464 Zinc deficiency results in increased expression of BHMT mRNA CTD PMID:12672911 zinc(0) increases expression EXP 6480464 Zinc deficiency results in increased expression of BHMT mRNA CTD PMID:12672911
Gene-Chemical Interaction Annotations
