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Gene: Ppid (peptidylprolyl isomerase D) Rattus norvegicus
Symbol: Ppid
Name: peptidylprolyl isomerase D
RGD ID: 1303174
Description: Exhibits cyclosporin A binding activity; enzyme binding activity; and peptidyl-prolyl cis-trans isomerase activity. Involved in several processes, including negative regulation of apoptotic process; protein peptidyl-prolyl isomerization; and regulation of mitochondrial membrane potential. Localizes to mitochondrion. Orthologous to human PPID (peptidylprolyl isomerase D); PARTICIPATES IN estrogen signaling pathway; calcium/calcium-mediated signaling pathway; Huntington's disease pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dibromophenyl 2,4,5-tribromophenyl ether; 2,4-dinitrotoluene.
Type: protein-coding
Also known as: 40 kDa peptidyl-prolyl cis-trans isomerase; Cyclophilin D; cyclophilin-40; Cyp-40; CypD; MGC93768; peptidyl-prolyl cis-trans isomerase D; peptidylprolyl isomerase D (cyclophilin D); PPIase; PPIase D; rotamase; rotamase D
Homo sapiens (human) : PPID (peptidylprolyl isomerase D)  HGNC  Alliance
Mus musculus (house mouse) : Ppid (peptidylprolyl isomerase D (cyclophilin D))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ppid (peptidylprolyl isomerase D)
Pan paniscus (bonobo/pygmy chimpanzee) : PPID (peptidylprolyl isomerase D)
Canis lupus familiaris (dog) : PPID (peptidylprolyl isomerase D)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ppid (peptidylprolyl isomerase D)
Sus scrofa (pig) : PPID (peptidylprolyl isomerase D)
Chlorocebus sabaeus (African green monkey) : PPID (peptidylprolyl isomerase D)
Heterocephalus glaber (naked mole-rat) : Ppid (peptidylprolyl isomerase D)
more info ...
Related Pseudogenes: Ppid-ps1  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Note: This gene encodes a 370 aa protein that is found in the cytoplasm. In some databases, it has been labeled incorrectly as 'cyclophilin D'. This same name has also been applied to a different protein, found in the mitochondrion, which is represented by GeneID 282819, Ppif. [13 Feb 2013]
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.02178,354,830 - 178,366,843 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2178,354,890 - 178,366,685 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02197,690,283 - 197,702,296 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42170,995,919 - 171,007,932 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12170,946,024 - 170,958,036 (+)NCBI
Celera2158,824,413 - 158,836,426 (+)NCBICelera
Cytogenetic Map2q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Ppid
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1303174
Created: 2004-12-03
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.