Acss1 (acyl-CoA synthetase short-chain family member 1) - Rat Genome Database

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Gene: Acss1 (acyl-CoA synthetase short-chain family member 1) Rattus norvegicus
Analyze
Symbol: Acss1
Name: acyl-CoA synthetase short-chain family member 1
RGD ID: 1306246
Description: Enables acetate-CoA ligase activity. Involved in acetate biosynthetic process and propionate biosynthetic process. Predicted to be located in mitochondrial matrix. Predicted to be active in mitochondrion. Orthologous to human ACSS1 (acyl-CoA synthetase short chain family member 1); PARTICIPATES IN disulfiram pharmacodynamics pathway; fatty acid beta degradation pathway; malonic aciduria pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Acas2l; acetyl-Coenzyme A synthetase 2 (AMP forming)-like; acetyl-coenzyme A synthetase 2-like, mitochondrial; LOC296259
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83159,910,809 - 159,960,748 (-)NCBIGRCr8
mRatBN7.23139,450,383 - 139,500,325 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3139,450,383 - 139,500,325 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3143,346,852 - 143,396,694 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03151,930,593 - 151,980,423 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03149,678,658 - 149,728,584 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03146,420,346 - 146,470,293 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3146,420,346 - 146,470,293 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03152,779,621 - 152,829,324 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43141,259,016 - 141,308,871 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13141,164,598 - 141,235,812 (-)NCBI
Celera3138,212,667 - 138,262,509 (-)NCBICelera
Cytogenetic Map3q41NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-dexrazoxane  (ISO)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2,4,6-tribromophenol  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrylamide  (EXP,ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (ISO)
amphetamine  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
choline  (ISO)
cocaine  (EXP)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) sulfate  (ISO)
Cuprizon  (EXP)
D-glucose  (ISO)
decabromodiphenyl ether  (ISO)
dextran sulfate  (ISO)
dibutyl phthalate  (ISO)
diethylstilbestrol  (ISO)
dioxygen  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
ethanol  (ISO)
ethylparaben  (ISO)
folic acid  (ISO)
fulvestrant  (ISO)
genistein  (ISO)
gentamycin  (EXP)
glucose  (ISO)
hydrogen peroxide  (ISO)
indole-3-methanol  (EXP)
L-methionine  (ISO)
lead(0)  (ISO)
leflunomide  (ISO)
lipopolysaccharide  (ISO)
MeIQx  (ISO)
menadione  (ISO)
N-acetyl-L-cysteine  (EXP)
N-nitrosodiethylamine  (EXP)
N-Nitrosopyrrolidine  (ISO)
O-methyleugenol  (ISO)
ochratoxin A  (EXP)
oxaliplatin  (EXP)
paracetamol  (ISO)
paraquat  (EXP)
perfluorohexanesulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
pirinixic acid  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
sodium acetate trihydrate  (ISO)
sodium arsenite  (ISO)
streptozocin  (ISO)
sunitinib  (ISO)
tebuconazole  (ISO)
temozolomide  (ISO)
testosterone  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
tributylstannane  (ISO)
trichloroethene  (EXP)
trovafloxacin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. The subcellular distribution of short-chain fatty acyl-CoA synthetase activity in rat tissues. Barth C, etal., Biochim Biophys Acta. 1971 Oct 5;248(1):24-33.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Glucose-independent Acetate Metabolism Promotes Melanoma Cell Survival and Tumor Growth. Lakhter AJ, etal., J Biol Chem. 2016 Oct 14;291(42):21869-21879. doi: 10.1074/jbc.M115.712166. Epub 2016 Aug 18.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Fasting-induced hypothermia and reduced energy production in mice lacking acetyl-CoA synthetase 2. Sakakibara I, etal., Cell Metab. 2009 Feb;9(2):191-202. doi: 10.1016/j.cmet.2008.12.008.
10. Evidence for 26 distinct acyl-coenzyme A synthetase genes in the human genome. Watkins PA, etal., J Lipid Res. 2007 Dec;48(12):2736-50. Epub 2007 Aug 30.
Additional References at PubMed
PMID:11150295   PMID:16788062   PMID:16790548   PMID:18614015   PMID:26945066   PMID:34800366  


Genomics

Comparative Map Data
Acss1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83159,910,809 - 159,960,748 (-)NCBIGRCr8
mRatBN7.23139,450,383 - 139,500,325 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3139,450,383 - 139,500,325 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3143,346,852 - 143,396,694 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03151,930,593 - 151,980,423 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03149,678,658 - 149,728,584 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03146,420,346 - 146,470,293 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3146,420,346 - 146,470,293 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03152,779,621 - 152,829,324 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43141,259,016 - 141,308,871 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13141,164,598 - 141,235,812 (-)NCBI
Celera3138,212,667 - 138,262,509 (-)NCBICelera
Cytogenetic Map3q41NCBI
ACSS1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382025,006,237 - 25,058,139 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2025,006,230 - 25,058,980 (-)EnsemblGRCh38hg38GRCh38
GRCh372024,986,873 - 25,038,775 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362024,934,873 - 24,987,616 (-)NCBINCBI36Build 36hg18NCBI36
Build 342024,934,873 - 24,987,616NCBI
Celera2025,060,679 - 25,113,427 (-)NCBICelera
Cytogenetic Map20p11.21NCBI
HuRef2024,943,703 - 24,995,659 (-)NCBIHuRef
CHM1_12024,987,355 - 25,039,309 (-)NCBICHM1_1
T2T-CHM13v2.02025,070,421 - 25,122,324 (-)NCBIT2T-CHM13v2.0
Acss1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392150,460,031 - 150,510,160 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2150,460,025 - 150,510,420 (-)EnsemblGRCm39 Ensembl
GRCm382150,618,111 - 150,668,240 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2150,618,105 - 150,668,500 (-)EnsemblGRCm38mm10GRCm38
MGSCv372150,443,847 - 150,493,976 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362150,309,552 - 150,359,670 (-)NCBIMGSCv36mm8
Celera2151,852,988 - 151,903,233 (-)NCBICelera
Cytogenetic Map2G3NCBI
cM Map274.74NCBI
Acss1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541531,117,303 - 31,154,654 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541531,117,542 - 31,154,654 (-)NCBIChiLan1.0ChiLan1.0
ACSS1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22125,877,357 - 25,932,094 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12025,874,190 - 25,928,929 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02024,946,629 - 25,001,311 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12025,294,186 - 25,348,109 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2025,293,511 - 25,349,017 (-)Ensemblpanpan1.1panPan2
ACSS1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1231,192,771 - 1,251,724 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl231,184,392 - 1,252,255 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha231,222,892 - 1,281,311 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0231,435,773 - 1,494,208 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl231,435,776 - 1,494,754 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1231,251,020 - 1,309,471 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0231,381,192 - 1,439,604 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0231,364,196 - 1,422,653 (-)NCBIUU_Cfam_GSD_1.0
Acss1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640147,319,248 - 147,380,019 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936620739,633 - 800,803 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936620739,633 - 800,472 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ACSS1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1730,800,427 - 30,839,742 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11730,800,536 - 30,839,799 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21734,949,412 - 34,988,665 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103247057
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_0236660872,048,170 - 2,100,706 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Acss1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624939394,884 - 435,098 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624939384,003 - 431,485 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Acss1
332 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:811
Count of miRNA genes:294
Interacting mature miRNAs:391
Transcripts:ENSRNOT00000009627
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2312673Scl63Serum cholesterol level QTL 630.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)398535255168026850Rat
1598877Bp285Blood pressure QTL 2851.50.03arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3120538241165538241Rat
1578653Vnigr3Vascular neointimal growth QTL 33.1artery morphology trait (VT:0002191)artery neointimal hyperplastic lesion area (CMO:0001414)3130656562169034231Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)398535386161695835Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
2298477Eau4Experimental allergic uveoretinitis QTL 40.0011uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)3137398739169034231Rat
1581568Rf53Renal function QTL 53urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
1578754Stresp16Stress response QTL 1640.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)3112681431157681431Rat
1300173Rf11Renal function QTL 113.38renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)3121056165145956249Rat
9589106Insul23Insulin level QTL 2313.860.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)3131635904169034231Rat
10755461Coatc16Coat color QTL 16coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)3122438700167438700Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)359242096157323038Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
1354611Despr2Despair related QTL 23.030.0028locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)397084464142084464Rat
2303620Vencon4Ventilatory control QTL 43.9respiration trait (VT:0001943)tidal volume (CMO:0000222)3127162703168026850Rat
631841Niddm39Non-insulin dependent diabetes mellitus QTL 393.36blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)394856903159898684Rat
1576306Schws3Schwannoma susceptibility QTL 30.001nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)3118839124163839124Rat
619618Rf3Renal disease susceptibility QTL 36.50.001urine albumin amount (VT:0002871)urine albumin excretion rate to body weight ratio (CMO:0001270)3107693393152693393Rat
1300159Kidm4Kidney mass QTL 43.83kidney mass (VT:0002707)right kidney wet weight to body weight ratio (CMO:0001953)3121056165157309487Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
2312659Slep7Serum leptin concentration QTL 70.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)398535255168026850Rat
631673Iddm13Insulin dependent diabetes mellitus QTL 131.30.663blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)3130193298161695983Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
1581546Pur13Proteinuria QTL 132.930.0335urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)378196190146592722Rat
1578656Vnigr2Vascular neointimal growth QTL 24.2artery morphology trait (VT:0002191)lesioned artery residual lumen area (CMO:0001417)3130656562169034231Rat
8552952Pigfal13Plasma insulin-like growth factor 1 level QTL 13blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)3138799500169034231Rat
631541Bp81Blood pressure QTL 814arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3124122556169034231Rat
2293087Iddm27Insulin dependent diabetes mellitus QTL 272.68blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)397551417147415807Rat
2312670Bw94Body weight QTL 940.01inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)398535255168026850Rat
724532Cm17Cardiac mass QTL 172heart mass (VT:0007028)calculated heart weight (CMO:0000073)395735366140735366Rat

Markers in Region
D3Rat148  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.03146,426,801 - 146,427,014NCBIRnor6.0
Rnor_5.03152,786,076 - 152,786,289UniSTSRnor5.0
RGSC_v3.43141,265,470 - 141,265,676RGDRGSC3.4
RGSC_v3.43141,265,471 - 141,265,676UniSTSRGSC3.4
RGSC_v3.13141,171,043 - 141,171,249RGD
Celera3138,219,122 - 138,219,291UniSTS
SHRSP x BN Map365.2999UniSTS
SHRSP x BN Map365.2999RGD
Cytogenetic Map3q41UniSTS
BF389773  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23139,463,124 - 139,463,298 (+)MAPPERmRatBN7.2
Rnor_6.03146,433,095 - 146,433,268NCBIRnor6.0
Rnor_5.03152,792,370 - 152,792,543UniSTSRnor5.0
RGSC_v3.43141,271,757 - 141,271,930UniSTSRGSC3.4
Celera3138,225,372 - 138,225,545UniSTS
RH 3.4 Map31197.32UniSTS
Cytogenetic Map3q41UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000009627   ⟹   ENSRNOP00000009627
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3139,450,383 - 139,500,325 (-)Ensembl
Rnor_6.0 Ensembl3146,420,346 - 146,470,293 (-)Ensembl
RefSeq Acc Id: NM_001106524   ⟹   NP_001099994
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83159,910,809 - 159,960,748 (-)NCBI
mRatBN7.23139,450,383 - 139,500,325 (-)NCBI
Rnor_6.03146,420,346 - 146,470,293 (-)NCBI
Rnor_5.03152,779,621 - 152,829,324 (-)NCBI
RGSC_v3.43141,259,016 - 141,308,871 (-)RGD
Celera3138,212,667 - 138,262,509 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001099994 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL86149 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000009627.4
RefSeq Acc Id: NP_001099994   ⟸   NM_001106524
- UniProtKB: D3ZZN3 (UniProtKB/TrEMBL),   A6KHF6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000009627   ⟸   ENSRNOT00000009627
Protein Domains
Acetyl-coenzyme A synthetase N-terminal   AMP-binding enzyme C-terminal   AMP-dependent synthetase/ligase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZZN3-F1-model_v2 AlphaFold D3ZZN3 1-682 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692516
Promoter ID:EPDNEW_R3041
Type:multiple initiation site
Name:Acss1_1
Description:acyl-CoA synthetase short-chain family member 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.03146,470,278 - 146,470,338EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306246 AgrOrtholog
BioCyc Gene G2FUF-47349 BioCyc
Ensembl Genes ENSRNOG00000007102 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000009627.6 UniProtKB/TrEMBL
Gene3D-CATH 3.30.300.30 UniProtKB/TrEMBL
  3.40.50.12780 UniProtKB/TrEMBL
InterPro Ac_CoA_lig_AcsA UniProtKB/TrEMBL
  ACAS_N UniProtKB/TrEMBL
  AMP-bd_C_sf UniProtKB/TrEMBL
  AMP-binding_CS UniProtKB/TrEMBL
  AMP-dep_Synth/Lig UniProtKB/TrEMBL
  AMP-dep_Synthh-like_sf UniProtKB/TrEMBL
  DUF4009 UniProtKB/TrEMBL
KEGG Report rno:296259 UniProtKB/TrEMBL
NCBI Gene 296259 ENTREZGENE
PANTHER ACETYL-COENZYME A SYNTHETASE UniProtKB/TrEMBL
  ACETYL-COENZYME A SYNTHETASE 2-LIKE, MITOCHONDRIAL UniProtKB/TrEMBL
Pfam ACAS_N UniProtKB/TrEMBL
  AMP-binding UniProtKB/TrEMBL
  DUF4009 UniProtKB/TrEMBL
PhenoGen Acss1 PhenoGen
PROSITE AMP_BINDING UniProtKB/TrEMBL
RatGTEx ENSRNOG00000007102 RatGTEx
Superfamily-SCOP Acetyl-CoA synthetase-like UniProtKB/TrEMBL
UniProt A6KHF6 ENTREZGENE, UniProtKB/TrEMBL
  D3ZZN3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Acss1  acyl-CoA synthetase short-chain family member 1   Acss1_predicted  acyl-CoA synthetase short-chain family member 1 (predicted)  'predicted' is removed 2292626 APPROVED
2008-01-09 Acss1_predicted  acyl-CoA synthetase short-chain family member 1 (predicted)  LOC681886  similar to acetyl-CoA synthetase 2-like  Data merged from RGD:1590480 1643240 APPROVED
2006-11-20 LOC681886  similar to acetyl-CoA synthetase 2-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-03-30 Acss1_predicted  acyl-CoA synthetase short-chain family member 1 (predicted)  Acas2l_predicted  acetyl-Coenzyme A synthetase 2 (AMP forming)-like (predicted)  Symbol and Name updated 1299863 APPROVED
2005-01-12 Acas2l_predicted  acetyl-Coenzyme A synthetase 2 (AMP forming)-like (predicted)      Symbol and Name status set to approved 70820 APPROVED