Etfdh (electron transfer flavoprotein dehydrogenase) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Etfdh (electron transfer flavoprotein dehydrogenase) Rattus norvegicus
Analyze
Symbol: Etfdh
Name: electron transfer flavoprotein dehydrogenase
RGD ID: 735052
Description: Enables electron transfer activity and iron-sulfur cluster binding activity. Predicted to be involved in electron transport chain; fatty acid beta-oxidation using acyl-CoA dehydrogenase; and response to oxidative stress. Located in mitochondrial membrane. Human ortholog(s) of this gene implicated in multiple acyl-CoA dehydrogenase deficiency. Orthologous to human ETFDH (electron transfer flavoprotein dehydrogenase); PARTICIPATES IN fatty acid beta degradation pathway; INTERACTS WITH (+)-schisandrin B; 2,4,6-trinitrotoluene; 3H-1,2-dithiole-3-thione.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: electron transfer flavoprotein-ubiquinone oxidoreductase precursor; electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial; electron transferring flavoprotein dehydrogenase; electron-transferring-flavoprotein dehydrogenase; ETF dehydrogenase; ETF-QO; ETF-ubiquinone oxidoreductase; MGC93785
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22164,740,547 - 164,762,754 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2164,729,749 - 164,762,745 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2171,958,548 - 171,980,851 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.02169,974,584 - 169,996,872 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.02164,583,426 - 164,605,716 (-)NCBIRnor_WKY
Rnor_6.02178,367,547 - 178,389,641 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2178,367,549 - 178,389,608 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02197,703,002 - 197,725,057 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42171,008,641 - 171,030,692 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12170,958,749 - 170,980,798 (-)NCBI
Celera2158,837,135 - 158,859,189 (-)NCBICelera
Cytogenetic Map2q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4,6-trinitrotoluene  (EXP)
2-hydroxypropanoic acid  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
acetamide  (EXP)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
amiodarone  (ISO)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP)
Brodifacoum  (EXP)
cadmium dichloride  (EXP)
carbamazepine  (ISO)
carbon nanotube  (ISO)
clofibrate  (EXP,ISO)
cobalt dichloride  (EXP)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
dibutyl phthalate  (EXP)
dicrotophos  (ISO)
disodium selenite  (ISO)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
endosulfan  (EXP)
epoxiconazole  (ISO)
fenofibrate  (EXP,ISO)
finasteride  (EXP)
flutamide  (EXP)
gentamycin  (EXP)
glafenine  (EXP)
isotretinoin  (ISO)
ivermectin  (ISO)
lipopolysaccharide  (ISO)
methapyrilene  (EXP)
mitoxantrone  (ISO)
Muraglitazar  (EXP)
N-nitrosomorpholine  (EXP)
ochratoxin A  (EXP)
paracetamol  (EXP,ISO)
perfluorooctanoic acid  (EXP)
phenylmercury acetate  (ISO)
pirinixic acid  (EXP,ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (EXP)
Soman  (EXP)
streptozocin  (ISO)
sulforaphane  (ISO)
sulindac  (EXP)
sunitinib  (ISO)
temozolomide  (ISO)
Tesaglitazar  (EXP)
tetrachloromethane  (EXP)
tetracycline  (ISO)
thioacetamide  (EXP)
tributylstannane  (EXP,ISO)
trichloroethene  (EXP)
triptonide  (ISO)
troglitazone  (EXP)
urethane  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)
zearalenone  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Acyl-CoA dehydrogenases. A mechanistic overview. Ghisla S and Thorpe C, Eur J Biochem. 2004 Feb;271(3):494-508.
3. cDNA cloning, functional expression and cellular localization of rat liver mitochondrial electron-transfer flavoprotein-ubiquinone oxidoreductase protein. Huang S, etal., Sci China C Life Sci. 2005 Aug;48(4):357-67.
4. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Comprehensive gene review and curation RGD comprehensive gene curation
11. Expression of human electron transfer flavoprotein-ubiquinone oxidoreductase from a baculovirus vector: kinetic and spectral characterization of the human protein. Simkovic M, etal., Biochem J 2002 Jun 15;364(Pt 3):659-67.
12. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:1332770   PMID:1991113   PMID:4052375   PMID:8306995   PMID:9334218   PMID:10423253   PMID:12865426   PMID:14640977   PMID:14651853   PMID:17023274   PMID:17050691   PMID:17412732  
PMID:18037314   PMID:18614015   PMID:21428728  


Genomics

Comparative Map Data
Etfdh
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22164,740,547 - 164,762,754 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2164,729,749 - 164,762,745 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2171,958,548 - 171,980,851 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.02169,974,584 - 169,996,872 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.02164,583,426 - 164,605,716 (-)NCBIRnor_WKY
Rnor_6.02178,367,547 - 178,389,641 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2178,367,549 - 178,389,608 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02197,703,002 - 197,725,057 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42171,008,641 - 171,030,692 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12170,958,749 - 170,980,798 (-)NCBI
Celera2158,837,135 - 158,859,189 (-)NCBICelera
Cytogenetic Map2q33NCBI
ETFDH
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384158,672,296 - 158,709,623 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl4158,671,968 - 158,710,742 (+)EnsemblGRCh38hg38GRCh38
GRCh374159,593,448 - 159,630,775 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364159,812,727 - 159,849,292 (+)NCBINCBI36Build 36hg18NCBI36
Build 344159,951,100 - 159,987,423NCBI
Celera4156,934,316 - 156,970,701 (+)NCBICelera
Cytogenetic Map4q32.1NCBI
HuRef4155,343,105 - 155,379,682 (+)NCBIHuRef
CHM1_14159,569,735 - 159,606,307 (+)NCBICHM1_1
T2T-CHM13v2.04162,023,044 - 162,060,372 (+)NCBIT2T-CHM13v2.0
Etfdh
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39379,511,095 - 79,536,074 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl379,511,095 - 79,536,807 (-)EnsemblGRCm39 Ensembl
GRCm38379,603,788 - 79,628,767 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl379,603,788 - 79,629,500 (-)EnsemblGRCm38mm10GRCm38
MGSCv37379,407,710 - 79,432,689 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36379,689,739 - 79,721,121 (-)NCBIMGSCv36mm8
Celera379,641,935 - 79,666,883 (-)NCBICelera
Cytogenetic Map3E3NCBI
cM Map334.91NCBI
Etfdh
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547112,289,857 - 12,348,167 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495547112,282,601 - 12,308,792 (+)NCBIChiLan1.0ChiLan1.0
ETFDH
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.14162,802,917 - 162,838,807 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4162,802,917 - 162,838,807 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v04150,992,123 - 151,028,698 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
ETFDH
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11555,752,170 - 55,781,118 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1555,752,200 - 55,792,105 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1556,114,006 - 56,142,677 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01556,495,410 - 56,525,823 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1556,495,413 - 56,525,811 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11555,734,215 - 55,762,881 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01555,833,373 - 55,862,247 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01556,147,031 - 56,175,699 (+)NCBIUU_Cfam_GSD_1.0
Etfdh
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530134,381,383 - 34,406,369 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365765,140,577 - 5,165,527 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ETFDH
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl847,608,772 - 47,657,436 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1847,608,499 - 47,655,889 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2850,013,348 - 50,060,554 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ETFDH
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.17105,214,231 - 105,252,100 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl7105,213,653 - 105,254,502 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603784,921,905 - 84,959,410 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Etfdh
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248483,639,294 - 3,677,517 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248483,639,559 - 3,673,771 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Etfdh
142 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:299
Count of miRNA genes:186
Interacting mature miRNAs:210
Transcripts:ENSRNOT00000013262
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
2293843Kiddil6Kidney dilation QTL 63.1kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)242804607182042367Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
1298085Bp165Blood pressure QTL 1650.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)243154682202446871Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)243154682202446871Rat
1354601Slep1Serum leptin concentration QTL 15.39blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)243171017184114403Rat
631266Bp132Blood pressure QTL 1320.0005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)246123260202447032Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)256043031202447032Rat
1298080Bp163Blood pressure QTL 1630.02arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118275202447032Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118463226797303Rat
1354605Rf48Renal function QTL 482.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)274786664206665859Rat
61374Edpm2Estrogen-dependent pituitary mass QTL 24.420.86pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)276539322202447032Rat
1581569Uae32Urinary albumin excretion QTL 320.0001urine protein amount (VT:0005160)urine albumin excretion rate (CMO:0000757)278665619219826953Rat
724534Uae6Urinary albumin excretion QTL 610urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)278665619249053267Rat
8662832Vetf7Vascular elastic tissue fragility QTL 73.5aorta elastin amount (VT:0003905)aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)281689826221035911Rat
1354622Kidm16Kidney mass QTL 163kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)281754530222436696Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)281754530227146641Rat
631507Bp105Blood pressure QTL 1050.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2112456140212696837Rat
634308Sach6Saccharin preference QTL 64.9taste sensitivity trait (VT:0001986)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)2112456140212696837Rat
1359030Bp277Blood pressure QTL 277arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2114837527185876470Rat
1359030Bp277Blood pressure QTL 277arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2114837527185876470Rat
1578648Bss11Bone structure and strength QTL 114.7femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)2114837527211674221Rat
1554319Bmd2Bone mineral density QTL 213.40.0001lumbar vertebra area (VT:0010570)lumbar vertebra cross-sectional area (CMO:0001689)2114837675212549332Rat
6907363Bp357Blood pressure QTL 3574.10.002arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2129540907174540907Rat
1300165Rf9Renal function QTL 93.28kidney glomerulus integrity trait (VT:0010546)index of glomerular damage (CMO:0001135)2133914684202447032Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2135552573202446871Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2135552573202446871Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2135552573202446871Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)2135552573202446871Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)2135552573202446871Rat
1298076Bp166Blood pressure QTL 1660.0009arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2136445150202447032Rat
1581502Esta3Estrogen-induced thymic atrophy QTL 3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)2136916935189599348Rat
1359022Ppulsi1Prepulse inhibition QTL 13.63prepulse inhibition trait (VT:0003088)acoustic startle response measurement (CMO:0001519)2136916935213594495Rat
1331794Bp202Blood pressure QTL 2023.66819arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2141194931223265385Rat
1331805Cm29Cardiac mass QTL 293.50746heart mass (VT:0007028)heart wet weight (CMO:0000069)2141194931223265385Rat
71113Cari2Carrageenan-induced inflammation QTL 22.70.009hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)2141596551202447032Rat
724568Uae13Urinary albumin excretion QTL 134.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)2143157029210020885Rat
10043136Iddm54Insulin dependent diabetes mellitus QTL 543.40.0001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2143657411190602963Rat
10043136Iddm54Insulin dependent diabetes mellitus QTL 543.40.0001blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)2143657411190602963Rat
6903312Bw112Body weight QTL 1123.20.0013body mass (VT:0001259)body weight (CMO:0000012)2143657569184114274Rat
61401Niddm2Non-insulin dependent diabetes mellitus QTL 24.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2144599348189599348Rat
631520Bp73Blood pressure QTL 730.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2147686913168355276Rat
1598833Bp295Blood pressure QTL 2953.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2147798556192798556Rat
1641925Alcrsp2Alcohol response QTL 2response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2149559561221167075Rat
1641891Alcrsp17Alcohol response QTL 17response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2149559561249053267Rat
1598805Memor8Memory QTL 83exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)2150341585189039377Rat
631501Bp101Blood pressure QTL 1012.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2150341684202446871Rat
2301966Bp322Blood pressure QTL 3223.58arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2150540301202447032Rat
1354609Niddm62Non-insulin dependent diabetes mellitus QTL 624.720.000006insulin secretion trait (VT:0003564)plasma insulin level (CMO:0000342)2150540301202447032Rat
12879845Cm89Cardiac mass QTL 890.008heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)2152413072175950118Rat
12879846Cm90Cardiac mass QTL 900.011heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)2152413072175950118Rat
12879847Am4Aortic mass QTL 40.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)2152413072175950118Rat
11565180Kidm56Kidney mass QTL 560.003kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)2152413072175950118Rat
11565181Bw176Body weight QTL 1760.002body mass (VT:0001259)body weight (CMO:0000012)2152413072175950118Rat
2301415Cm67Cardiac mass QTL 670.003heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)2152413072175950118Rat
12879836Kidm61Kidney mass QTL 610.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)2152413072185122374Rat
12879837Am2Aortic mass QTL 20.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)2152413072185122374Rat
12879838Cm86Cardiac mass QTL 860.002heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)2152413072185122374Rat
12879839Cm85Cardiac mass QTL 850.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)2152413072185122374Rat
12879840Bw179Body weight QTL 1790.005body mass (VT:0001259)body weight (CMO:0000012)2152413072185122374Rat
1359032Hrtrt18Heart rate QTL 18heart pumping trait (VT:2000009)heart rate (CMO:0000002)2157142078192625452Rat
1358900Bw48Body weight QTL 484.88body mass (VT:0001259)body weight (CMO:0000012)2157142078211086598Rat
8662843Vetf9Vascular elastic tissue fragility QTL 92.05thoracic aorta molecular composition trait (VT:0010568)aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)2157142078226277316Rat
1302793Bw16Body weight QTL 1650.0001body mass (VT:0001259)body weight (CMO:0000012)2157142209202446871Rat
7488925Bp364Blood pressure QTL 3640.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2160564068205564068Rat
1358356Srcrt1Stress Responsive Cort QTL13.66blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)2161699179222436696Rat
7488927Bp365Blood pressure QTL 3650.008arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2162765032207765032Rat
2306901Bp337Blood pressure QTL 3370.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2164073756227146641Rat

Markers in Region
RH128555  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22164,740,672 - 164,740,861 (+)MAPPERmRatBN7.2
Rnor_6.02178,367,666 - 178,367,854NCBIRnor6.0
Rnor_5.02197,703,119 - 197,703,307UniSTSRnor5.0
RGSC_v3.42171,008,755 - 171,008,943UniSTSRGSC3.4
Celera2158,837,249 - 158,837,437UniSTS
RH 3.4 Map21060.2UniSTS
Cytogenetic Map2q32UniSTS
AV001013  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22164,741,620 - 164,741,701 (+)MAPPERmRatBN7.2
Rnor_6.02178,368,614 - 178,368,694NCBIRnor6.0
Rnor_5.02197,704,067 - 197,704,147UniSTSRnor5.0
RGSC_v3.42171,009,703 - 171,009,783UniSTSRGSC3.4
Celera2158,838,197 - 158,838,277UniSTS
Cytogenetic Map2q32UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 40 11 8
Low 1
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000013262   ⟹   ENSRNOP00000013262
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2164,740,245 - 164,762,624 (-)Ensembl
Rnor_6.0 Ensembl2178,367,549 - 178,389,608 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000100343   ⟹   ENSRNOP00000082804
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2164,732,409 - 164,762,624 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000104112   ⟹   ENSRNOP00000078068
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2164,729,749 - 164,762,624 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000105634   ⟹   ENSRNOP00000077926
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2164,740,250 - 164,762,745 (-)Ensembl
RefSeq Acc Id: NM_198742   ⟹   NP_942037
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22164,740,559 - 164,762,611 (-)NCBI
Rnor_6.02178,367,552 - 178,389,603 (-)NCBI
Rnor_5.02197,703,002 - 197,725,057 (-)NCBI
RGSC_v3.42171,008,641 - 171,030,692 (-)RGD
Celera2158,837,135 - 158,859,189 (-)RGD
Sequence:
RefSeq Acc Id: XM_006232507   ⟹   XP_006232569
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22164,740,556 - 164,762,611 (-)NCBI
Rnor_6.02178,367,549 - 178,389,603 (-)NCBI
Rnor_5.02197,703,002 - 197,725,057 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008761084   ⟹   XP_008759306
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22164,740,547 - 164,762,754 (-)NCBI
Rnor_6.02178,367,547 - 178,389,641 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_942037   ⟸   NM_198742
- Peptide Label: precursor
- UniProtKB: Q66HF3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006232569   ⟸   XM_006232507
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_008759306   ⟸   XM_008761084
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSRNOP00000013262   ⟸   ENSRNOT00000013262
RefSeq Acc Id: ENSRNOP00000077926   ⟸   ENSRNOT00000105634
RefSeq Acc Id: ENSRNOP00000078068   ⟸   ENSRNOT00000104112
RefSeq Acc Id: ENSRNOP00000082804   ⟸   ENSRNOT00000100343
Protein Domains
4Fe-4S ferredoxin-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6UPE1-F1-model_v2 AlphaFold Q6UPE1 1-616 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691386
Promoter ID:EPDNEW_R1910
Type:initiation region
Name:Etfdh_1
Description:electron transfer flavoprotein dehydrogenase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02178,389,576 - 178,389,636EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:735052 AgrOrtholog
BioCyc Gene G2FUF-52727 BioCyc
Ensembl Genes ENSRNOG00000009538 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000013262 ENTREZGENE
  ENSRNOP00000013262.5 UniProtKB/TrEMBL
  ENSRNOP00000077926 ENTREZGENE
  ENSRNOP00000077926.1 UniProtKB/TrEMBL
  ENSRNOP00000078068 ENTREZGENE
  ENSRNOP00000078068.1 UniProtKB/TrEMBL
  ENSRNOP00000082804.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000013262 ENTREZGENE
  ENSRNOT00000013262.7 UniProtKB/TrEMBL
  ENSRNOT00000100343.1 UniProtKB/TrEMBL
  ENSRNOT00000104112 ENTREZGENE
  ENSRNOT00000104112.1 UniProtKB/TrEMBL
  ENSRNOT00000105634 ENTREZGENE
  ENSRNOT00000105634.1 UniProtKB/TrEMBL
Gene3D-CATH 3.50.50.60 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7109511 IMAGE-MGC_LOAD
InterPro 4Fe4S_Fe-S-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ETF-QO UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FAD/NAD-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:295143 UniProtKB/TrEMBL
MGC_CLONE MGC:93785 IMAGE-MGC_LOAD
NCBI Gene 295143 ENTREZGENE
PANTHER PTHR10617 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Etfdh PhenoGen
PROSITE 4FE4S_FER_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF51905 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5Y801_RAT UniProtKB/TrEMBL
  A0A8I5Y9W6_RAT UniProtKB/TrEMBL
  A0A8I5ZXZ1_RAT UniProtKB/TrEMBL
  ETFD_RAT UniProtKB/Swiss-Prot
  F7ELJ5_RAT UniProtKB/TrEMBL
  Q66HF3 ENTREZGENE, UniProtKB/TrEMBL
  Q6UPE1 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-01-13 Etfdh  electron transfer flavoprotein dehydrogenase  Etfdh  electron-transferring-flavoprotein dehydrogenase  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-07-08 Etfdh  electron-transferring-flavoprotein dehydrogenase      Symbol and Name status set to approved 1299863 APPROVED