Vdac2 (voltage-dependent anion channel 2) - Rat Genome Database

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Gene: Vdac2 (voltage-dependent anion channel 2) Rattus norvegicus
Analyze
Symbol: Vdac2
Name: voltage-dependent anion channel 2
RGD ID: 621576
Description: Predicted to enable several functions, including cholesterol binding activity; phosphatidylcholine binding activity; and voltage-gated anion channel activity. Predicted to be involved in several processes, including binding activity of sperm to zona pellucida; mitochondrial outer membrane permeabilization; and negative regulation of intrinsic apoptotic signaling pathway. Located in mitochondrion and synaptic vesicle. Used to study myocardial infarction and visual epilepsy. Biomarker of temporal lobe epilepsy. Orthologous to human VDAC2 (voltage dependent anion channel 2); PARTICIPATES IN calcium/calcium-mediated signaling pathway; Huntington's disease pathway; Parkinson's disease pathway; INTERACTS WITH 1,2,4-trimethylbenzene; 2,2,2-tetramine; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: B36-VDAC; outer mitochondrial membrane protein porin 2; VDAC-2; voltage-dependent anion-selective channel protein 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2152,462,877 - 2,476,802 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl152,463,056 - 2,476,553 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx152,470,328 - 2,484,006 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0153,856,774 - 3,870,452 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0152,469,123 - 2,482,800 (-)NCBIRnor_WKY
Rnor_6.0152,634,622 - 2,648,548 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl152,634,624 - 2,648,551 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0152,615,635 - 2,629,561 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4152,515,297 - 2,528,969 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1152,515,298 - 2,528,969 (-)NCBI
Celera152,105,517 - 2,119,199 (+)NCBICelera
Cytogenetic Map15p16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,2,4-trimethylbenzene  (EXP)
1,2-dimethylhydrazine  (ISO)
2,2,2-tetramine  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-dinitrotoluene  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diisothiocyano-trans-stilbene-2,2'-disulfonic acid  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxynon-2-enal  (ISO)
aconitine  (EXP)
all-trans-retinoic acid  (ISO)
amiodarone  (ISO)
ammonium chloride  (EXP)
Aroclor 1254  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (ISO)
bisphenol F  (ISO)
Brodifacoum  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
clobetasol  (ISO)
copper(II) chloride  (ISO)
cyclosporin A  (ISO)
deguelin  (ISO)
desferrioxamine B  (ISO)
dexamethasone  (ISO)
diallyl trisulfide  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (ISO)
disodium selenite  (ISO)
dopamine  (ISO)
doxorubicin  (ISO)
enzyme inhibitor  (ISO)
erastin  (EXP,ISO)
ethanol  (ISO)
fenthion  (ISO)
fenvalerate  (EXP)
ferric ammonium citrate  (ISO)
flutamide  (EXP)
fulvestrant  (ISO)
gentamycin  (EXP)
hydrogen peroxide  (ISO)
indometacin  (ISO)
ivermectin  (ISO)
josamycin  (ISO)
ketamine  (EXP)
methamphetamine  (EXP)
methidathion  (ISO)
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine  (EXP)
N-acetyl-L-cysteine  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-methyl-D-aspartic acid  (ISO)
N-nitrosomorpholine  (EXP)
p-menthan-3-ol  (ISO)
paracetamol  (ISO)
phenobarbital  (EXP,ISO)
picoxystrobin  (ISO)
potassium chromate  (ISO)
quercetin  (ISO)
rotenone  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (EXP,ISO)
streptozocin  (EXP)
T-2 toxin  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (EXP)
tolcapone  (EXP)
uranium atom  (ISO)
valproic acid  (ISO)
vanadium atom  (ISO)
vanadium(0)  (ISO)
zinc sulfate  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Proteomic analysis reveals late exercise effects on cardiac remodeling following myocardial infarction. Bansal A, etal., J Proteomics. 2010 Sep 10;73(10):2041-9. doi: 10.1016/j.jprot.2010.06.009. Epub 2010 Jul 1.
2. All three isoforms of the voltage-dependent anion channel (VDAC1, VDAC2, and VDAC3) are present in mitochondria from bovine, rabbit, and rat brain. Cesar Mde C and Wilson JE, Arch Biochem Biophys. 2004 Feb 15;422(2):191-6.
3. [Voltage dependent anion channel 2 involved mitochondrial apoptosis and its possible regulatory signal pathway in hearts of rats with severe scalds]. Feng YQ, etal., Zhonghua Yi Xue Za Zhi. 2013 Mar 26;93(12):939-43.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
6. Preliminary explorations of the role of mitochondrial proteins in refractory epilepsy: some findings from comparative proteomics. Jiang W, etal., J Neurosci Res. 2007 Nov 1;85(14):3160-70.
7. Comparative proteomics and correlated signaling network of rat hippocampus in the pilocarpine model of temporal lobe epilepsy. Liu XY, etal., Proteomics. 2008 Feb;8(3):582-603. doi: 10.1002/pmic.200700514.
8. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
9. The proteome of the presynaptic active zone: from docked synaptic vesicles to adhesion molecules and maxi-channels. Morciano M, etal., J Neurochem. 2009 Feb;108(3):662-75. doi: 10.1111/j.1471-4159.2008.05824.x.
10. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
11. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
12. GOA pipeline RGD automated data pipeline
13. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
14. Comprehensive gene review and curation RGD comprehensive gene curation
15. Characterization of porin isoforms expressed in tumor cells. Shinohara Y, etal., Eur J Biochem 2000 Oct;267(19):6067-73.
16. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:1373732   PMID:8420959   PMID:12865426   PMID:12881569   PMID:14651853   PMID:15489334   PMID:17634366   PMID:18063578   PMID:18504258   PMID:18614015   PMID:18802025   PMID:19688190  
PMID:20833797   PMID:21605504   PMID:21630459   PMID:22082260   PMID:22867515   PMID:23106098   PMID:23355646   PMID:23376485   PMID:24625528   PMID:25204797   PMID:26316108   PMID:29476059  
PMID:30624982   PMID:32357304   PMID:33450132  


Genomics

Comparative Map Data
Vdac2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2152,462,877 - 2,476,802 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl152,463,056 - 2,476,553 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx152,470,328 - 2,484,006 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0153,856,774 - 3,870,452 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0152,469,123 - 2,482,800 (-)NCBIRnor_WKY
Rnor_6.0152,634,622 - 2,648,548 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl152,634,624 - 2,648,551 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0152,615,635 - 2,629,561 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4152,515,297 - 2,528,969 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1152,515,298 - 2,528,969 (-)NCBI
Celera152,105,517 - 2,119,199 (+)NCBICelera
Cytogenetic Map15p16NCBI
VDAC2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381075,210,170 - 75,231,448 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1075,210,154 - 75,231,448 (+)EnsemblGRCh38hg38GRCh38
GRCh371076,969,928 - 76,991,206 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361076,640,569 - 76,661,212 (+)NCBINCBI36Build 36hg18NCBI36
Build 341076,640,568 - 76,661,210NCBI
Celera1070,258,168 - 70,279,465 (+)NCBICelera
Cytogenetic Map10q22.2NCBI
HuRef1070,968,331 - 70,989,598 (+)NCBIHuRef
CHM1_11077,251,734 - 77,273,028 (+)NCBICHM1_1
T2T-CHM13v2.01076,083,655 - 76,104,942 (+)NCBIT2T-CHM13v2.0
Vdac2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391421,881,629 - 21,895,947 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1421,875,306 - 21,895,947 (+)EnsemblGRCm39 Ensembl
GRCm381421,831,561 - 21,845,879 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1421,825,238 - 21,845,879 (+)EnsemblGRCm38mm10GRCm38
MGSCv371422,650,783 - 22,665,101 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361420,620,113 - 20,634,431 (+)NCBIMGSCv36mm8
Celera1418,214,291 - 18,228,576 (+)NCBICelera
Cytogenetic Map14A3NCBI
cM Map1411.91NCBI
Vdac2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543716,853,433 - 16,872,345 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543716,857,715 - 16,871,717 (-)NCBIChiLan1.0ChiLan1.0
VDAC2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11074,403,221 - 74,411,762 (+)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v01071,739,395 - 71,763,835 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
VDAC2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1425,449,926 - 25,462,147 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl425,449,442 - 25,462,335 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha425,585,079 - 25,597,491 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0425,732,572 - 25,744,990 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl425,732,597 - 25,753,031 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1425,627,631 - 25,640,037 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0425,828,227 - 25,840,628 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0426,184,477 - 26,196,904 (+)NCBIUU_Cfam_GSD_1.0
Vdac2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721355,629,722 - 55,643,567 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365214,122,447 - 4,136,228 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
VDAC2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1477,766,686 - 77,782,322 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11477,767,165 - 77,782,327 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
VDAC2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1956,141,153 - 56,160,378 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl956,136,756 - 56,157,173 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604816,628,451 - 16,649,525 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Vdac2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247548,587,920 - 8,602,761 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247548,587,698 - 8,601,757 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Position Markers
RH135028  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2152,462,675 - 2,462,856 (+)MAPPERmRatBN7.2
Rnor_6.0152,634,421 - 2,634,601NCBIRnor6.0
Rnor_5.0152,615,434 - 2,615,614UniSTSRnor5.0
RGSC_v3.4152,515,096 - 2,515,276UniSTSRGSC3.4
Celera152,119,220 - 2,119,400UniSTS
RH 3.4 Map1544.6UniSTS
Cytogenetic Map15p16UniSTS
AA900297  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2152,463,295 - 2,463,434 (+)MAPPERmRatBN7.2
Rnor_6.0152,635,041 - 2,635,179NCBIRnor6.0
Rnor_5.0152,616,054 - 2,616,192UniSTSRnor5.0
RGSC_v3.4152,515,716 - 2,515,854UniSTSRGSC3.4
Celera152,118,642 - 2,118,780UniSTS
RH 3.4 Map1546.3UniSTS
Cytogenetic Map15p16UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354657Despr13Despair related QTL 130.0022locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)15129912054Rat
8552920Pigfal8Plasma insulin-like growth factor 1 level QTL 83blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)15134723002Rat
8694361Abfw6Abdominal fat weight QTL 610.20.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)15134723002Rat
9589149Insul29Insulin level QTL 299.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)15134723002Rat
731170Pur3Proteinuria QTL 32.30.0005urine protein amount (VT:0005160)urine protein excretion rate (CMO:0000759)15141686771Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15142356671Rat
2298549Neuinf12Neuroinflammation QTL 123.5nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)15155302115Rat
10401805Kidm51Kidney mass QTL 51kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1530632945306329Rat
5684946Bss98Bone structure and strength QTL 983.90.0026tibia strength trait (VT:1000284)tibia ultimate force (CMO:0001734)15105825014481294Rat
1641913Colcr2Colorectal carcinoma resistance QTL 26.570.0197intestine integrity trait (VT:0010554)colorectal tumor number (CMO:0001794)15226636822711984Rat
1641913Colcr2Colorectal carcinoma resistance QTL 26.570.0197intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)15226636822711984Rat
738017Hcas7Hepatocarcinoma susceptibility QTL 72.91liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)15226636846921453Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:92
Count of miRNA genes:73
Interacting mature miRNAs:86
Transcripts:ENSRNOT00000018462
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000018462   ⟹   ENSRNOP00000018462
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl152,467,361 - 2,476,553 (-)Ensembl
Rnor_6.0 Ensembl152,634,624 - 2,648,294 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000086864   ⟹   ENSRNOP00000074839
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl152,463,056 - 2,475,565 (-)Ensembl
Rnor_6.0 Ensembl152,634,800 - 2,648,551 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000110275   ⟹   ENSRNOP00000083875
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl152,463,056 - 2,476,063 (-)Ensembl
RefSeq Acc Id: NM_031354   ⟹   NP_112644
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2152,462,877 - 2,476,548 (-)NCBI
Rnor_6.0152,634,622 - 2,648,294 (-)NCBI
Rnor_5.0152,615,635 - 2,629,561 (-)NCBI
RGSC_v3.4152,515,297 - 2,528,969 (-)RGD
Celera152,105,517 - 2,119,199 (+)RGD
Sequence:
RefSeq Acc Id: XM_006251661   ⟹   XP_006251723
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2152,463,052 - 2,476,802 (-)NCBI
Rnor_6.0152,634,801 - 2,648,548 (-)NCBI
Rnor_5.0152,615,635 - 2,629,561 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_112644 (Get FASTA)   NCBI Sequence Viewer  
  XP_006251723 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAF80116 (Get FASTA)   NCBI Sequence Viewer  
  AAH63164 (Get FASTA)   NCBI Sequence Viewer  
  BAB13474 (Get FASTA)   NCBI Sequence Viewer  
  P81155 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_112644   ⟸   NM_031354
- UniProtKB: Q9JI32 (UniProtKB/Swiss-Prot),   P81155 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006251723   ⟸   XM_006251661
- Peptide Label: isoform X1
- UniProtKB: Q9JI32 (UniProtKB/Swiss-Prot),   P81155 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000018462   ⟸   ENSRNOT00000018462
RefSeq Acc Id: ENSRNOP00000074839   ⟸   ENSRNOT00000086864
RefSeq Acc Id: ENSRNOP00000083875   ⟸   ENSRNOT00000110275

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P81155-F1-model_v2 AlphaFold P81155 1-295 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699546
Promoter ID:EPDNEW_R10070
Type:initiation region
Name:Vdac2_1
Description:voltage-dependent anion channel 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0152,648,259 - 2,648,319EPDNEW

Strain Variation

Strain Sequence Variants (mRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621576 AgrOrtholog
BioCyc Gene G2FUF-14601 BioCyc
Ensembl Genes ENSRNOG00000013505 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000018462.6 UniProtKB/TrEMBL
  ENSRNOP00000074839 ENTREZGENE
  ENSRNOP00000074839.2 UniProtKB/TrEMBL
  ENSRNOP00000083875.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000018462.7 UniProtKB/TrEMBL
  ENSRNOT00000086864 ENTREZGENE
  ENSRNOT00000086864.2 UniProtKB/TrEMBL
  ENSRNOT00000110275.1 UniProtKB/TrEMBL
Gene3D-CATH 2.40.160.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:6921675 IMAGE-MGC_LOAD
InterPro Porin_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Porin_Euk UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Porin_Euk/Tom40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  VDAC2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:83531 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72774 IMAGE-MGC_LOAD
NCBI Gene 83531 ENTREZGENE
PANTHER PTHR11743 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11743:SF12 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Porin_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Vdac2 PhenoGen
PRINTS EUKARYTPORIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE EUKARYOTIC_PORIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6GB84_RAT UniProtKB/TrEMBL
  A0A8L2UJ74_RAT UniProtKB/TrEMBL
  A0A8L2URG2_RAT UniProtKB/TrEMBL
  P81155 ENTREZGENE
  Q9JI32 ENTREZGENE
  VDAC2_RAT UniProtKB/Swiss-Prot
UniProt Secondary Q9JI32 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Vdac2  voltage-dependent anion channel 2      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Vdac2  voltage-dependent anion channel 2      Symbol and Name status set to provisional 70820 PROVISIONAL