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Gene: Ngef (neuronal guanine nucleotide exchange factor) Rattus norvegicus
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Symbol: Ngef
Name: neuronal guanine nucleotide exchange factor
Description: Predicted to have ephrin receptor binding activity and guanyl-nucleotide exchange factor activity. Predicted to be involved in several processes, including ephrin receptor signaling pathway; negative regulation of dendritic spine morphogenesis; and synapse pruning. Predicted to localize to the glutamatergic synapse. Orthologous to human NGEF (neuronal guanine nucleotide exchange factor); PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis; INTERACTS WITH 1,2-dimethylhydrazine; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Besh3; brain-enriched SH3-domain protein Besh3; eph-interacting exchange protein; ephexin-1; LOC360451
Orthologs:
Homo sapiens (human) : NGEF (neuronal guanine nucleotide exchange factor)  HGNC  Alliance
Mus musculus (house mouse) : Ngef (neuronal guanine nucleotide exchange factor)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ngef (neuronal guanine nucleotide exchange factor)
Pan paniscus (bonobo/pygmy chimpanzee) : NGEF (neuronal guanine nucleotide exchange factor)
Canis lupus familiaris (dog) : NGEF (neuronal guanine nucleotide exchange factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ngef (neuronal guanine nucleotide exchange factor)
Sus scrofa (pig) : NGEF (neuronal guanine nucleotide exchange factor)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0994,569,286 - 94,601,852 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0994,290,729 - 94,323,295 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4986,294,206 - 86,327,765 (-)NCBIRGSC3.4rn4RGSC3.4
Celera985,556,597 - 85,590,171 (-)NCBICelera
Cytogenetic Map9q35NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Ngef
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1309055
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.