Gene: Mpg (N-methylpurine-DNA glycosylase) Rattus norvegicus
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Symbol: Mpg
Name: N-methylpurine-DNA glycosylase
Description: ENCODES a protein that exhibits alkylbase DNA N-glycosylase activity (ortholog); INVOLVED IN base-excision repair (ortholog); PARTICIPATES IN base excision repair pathway; FOUND IN mitochondrial nucleoid (inferred); nucleus (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene
AGR Description: Predicted to have alkylbase DNA N-glycosylase activity; predicted to be involved in base-excision repair; predicted to localize to the mitochondrial nucleoid and nucleus; orthologous to human MPG (N-methylpurine DNA glycosylase).
Merged Description: Predicted to have alkylbase DNA N-glycosylase activity; predicted to be involved in base-excision repair; predicted to localize to the mitochondrial nucleoid and nucleus; orthologous to human MPG (N-methylpurine DNA glycosylase); PARTICIPATES IN base excision repair pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 3-alkyladenine DNA glycosylase; 3-methyladenine DNA glycosidase; ADPG; DNA-3-methyladenine glycosylase; N-methylpurine-DNA glycocylase
Orthologs:
Homo sapiens (human) : MPG (N-methylpurine DNA glycosylase)  HGNC  Alliance
Mus musculus (house mouse) : Mpg (N-methylpurine-DNA glycosylase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mpg (N-methylpurine DNA glycosylase)
Pan paniscus (bonobo/pygmy chimpanzee) : MPG (N-methylpurine DNA glycosylase)
Canis lupus familiaris (dog) : MPG (N-methylpurine DNA glycosylase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mpg (N-methylpurine DNA glycosylase)
Sus scrofa (pig) : MPG (N-methylpurine DNA glycosylase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01015,661,768 - 15,667,995 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01015,556,911 - 15,563,138 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41015,643,334 - 15,649,561 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11015,644,406 - 15,650,564 (-)NCBI
Celera1015,063,825 - 15,070,052 (-)NCBICelera
Cytogenetic Map10q12NCBI
RH 3.4 Map10149.16RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Mpg
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3106
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.