Slc7a7 (solute carrier family 7 member 7) - Rat Genome Database

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Gene: Slc7a7 (solute carrier family 7 member 7) Rattus norvegicus
Analyze
Symbol: Slc7a7
Name: solute carrier family 7 member 7
RGD ID: 619902
Description: Predicted to enable L-arginine transmembrane transporter activity. Predicted to be involved in L-arginine transmembrane transport; L-leucine transport; and regulation of arginine metabolic process. Predicted to be located in basolateral plasma membrane. Human ortholog(s) of this gene implicated in lysinuric protein intolerance. Orthologous to human SLC7A7 (solute carrier family 7 member 7); PARTICIPATES IN amiloride pharmacodynamics pathway; bendroflumethiazide pharmacodynamics pathway; bumetanide pharmacodynamics pathway; INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: solute carrier family 7 (amino acid transporter light chain, y+L system), member 7; solute carrier family 7 (cationic amino acid transporter, y+ system), member 7; solute carrier family 7 (cationic amino acid transporter, y+system), member 7; y%2BLAT1; y(+)L-type amino acid transporter 1; y+L amino acid transporter 1; y+LAT-1; y+LAT1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81531,792,122 - 31,852,732 (-)NCBIGRCr8
mRatBN7.21527,822,088 - 27,873,121 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1527,822,091 - 27,865,648 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1529,663,224 - 29,704,911 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01530,810,436 - 30,852,128 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01529,060,489 - 29,102,814 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01533,013,346 - 33,059,733 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1533,013,504 - 33,051,129 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01536,894,258 - 36,945,548 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41532,431,748 - 32,471,526 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11532,447,447 - 32,487,226 (-)NCBI
Celera1527,403,911 - 27,448,739 (-)NCBICelera
Cytogenetic Map15p13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP)
17beta-estradiol 3-benzoate  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
3-chloropropane-1,2-diol  (EXP)
4-nonylphenol  (ISO)
4-tert-Octylphenol  (ISO)
acetamide  (EXP)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
beta-lapachone  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP)
Butylbenzyl phthalate  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
calciol  (ISO)
calcitriol  (ISO)
carbamazepine  (ISO)
cefaloridine  (EXP)
CGP 52608  (ISO)
choline  (ISO)
ciguatoxin CTX1B  (ISO)
cisplatin  (EXP,ISO)
clofibric acid  (EXP)
cobalt dichloride  (EXP)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
cytarabine  (ISO)
DDE  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
diethyl phthalate  (ISO)
diisobutyl phthalate  (ISO)
diisononyl phthalate  (ISO)
dorsomorphin  (ISO)
epoxiconazole  (ISO)
folic acid  (ISO)
genistein  (EXP)
gentamycin  (EXP)
glafenine  (EXP)
glyphosate  (EXP)
hydrogen chloride  (ISO)
hydrogen peroxide  (ISO)
lidocaine  (EXP)
mercury dibromide  (ISO)
mercury dichloride  (EXP)
methapyrilene  (ISO)
methoxychlor  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
N(4)-hydroxycytidine  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
nickel atom  (ISO)
nickel dichloride  (EXP)
nitric oxide  (ISO)
okadaic acid  (ISO)
oxycodone  (EXP)
ozone  (EXP)
p-chloromercuribenzoic acid  (ISO)
p-tert-Amylphenol  (ISO)
paracetamol  (EXP,ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
resveratrol  (EXP)
SB 431542  (ISO)
silicon dioxide  (EXP,ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP,ISO)
streptozocin  (EXP)
sunitinib  (ISO)
tamoxifen  (ISO)
testosterone  (EXP)
thioacetamide  (EXP)
titanium dioxide  (EXP)
toluene  (EXP)
trichloroethene  (EXP)
triclosan  (ISO)
triphenyl phosphate  (ISO)
troglitazone  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)
zidovudine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Comprehensive gene review and curation RGD comprehensive gene curation
11. Five novel SLC7A7 variants and y+L gene-expression pattern in cultured lymphoblasts from Japanese patients with lysinuric protein intolerance. Shoji Y, etal., Hum Mutat 2002 Nov;20(5):375-81.
12. Identification of SLC7A7, encoding y+LAT-1, as the lysinuric protein intolerance gene. Torrents D, etal., Nat Genet. 1999 Mar;21(3):293-6.
Additional References at PubMed
PMID:27075   PMID:12477932   PMID:17376816   PMID:19388351  


Genomics

Comparative Map Data
Slc7a7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81531,792,122 - 31,852,732 (-)NCBIGRCr8
mRatBN7.21527,822,088 - 27,873,121 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1527,822,091 - 27,865,648 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1529,663,224 - 29,704,911 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01530,810,436 - 30,852,128 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01529,060,489 - 29,102,814 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01533,013,346 - 33,059,733 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1533,013,504 - 33,051,129 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01536,894,258 - 36,945,548 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41532,431,748 - 32,471,526 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11532,447,447 - 32,487,226 (-)NCBI
Celera1527,403,911 - 27,448,739 (-)NCBICelera
Cytogenetic Map15p13NCBI
SLC7A7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381422,773,222 - 22,819,791 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1422,773,222 - 22,829,820 (-)EnsemblGRCh38hg38GRCh38
GRCh371423,242,431 - 23,289,000 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361422,312,274 - 22,354,852 (-)NCBINCBI36Build 36hg18NCBI36
Build 341422,312,273 - 22,354,852NCBI
Celera143,105,324 - 3,151,896 (-)NCBICelera
Cytogenetic Map14q11.2NCBI
HuRef143,359,761 - 3,406,230 (-)NCBIHuRef
CHM1_11423,241,135 - 23,287,712 (-)NCBICHM1_1
T2T-CHM13v2.01416,971,294 - 17,017,861 (-)NCBIT2T-CHM13v2.0
Slc7a7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391454,606,899 - 54,657,525 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1454,606,899 - 54,655,237 (-)EnsemblGRCm39 Ensembl
GRCm381454,369,442 - 54,420,068 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1454,369,442 - 54,417,780 (-)EnsemblGRCm38mm10GRCm38
MGSCv371454,989,128 - 55,036,536 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361453,324,494 - 53,371,884 (-)NCBIMGSCv36mm8
Celera1452,159,883 - 52,209,770 (-)NCBICelera
Cytogenetic Map14C2NCBI
cM Map1427.76NCBI
Slc7a7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540937,468,583 - 37,513,533 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540937,467,151 - 37,513,533 (+)NCBIChiLan1.0ChiLan1.0
SLC7A7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21524,202,947 - 24,254,843 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11423,419,433 - 23,467,549 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0143,590,781 - 3,637,588 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11421,690,145 - 21,739,127 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1421,690,145 - 21,738,057 (-)Ensemblpanpan1.1panPan2
SLC7A7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.183,132,735 - 3,209,259 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl83,133,139 - 3,165,832 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha83,081,395 - 3,157,612 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.083,239,629 - 3,273,375 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.182,932,046 - 3,008,332 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.082,993,543 - 3,070,112 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.083,255,669 - 3,332,090 (-)NCBIUU_Cfam_GSD_1.0
Slc7a7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864034,865,203 - 34,924,630 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367221,478,240 - 1,527,121 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367221,464,252 - 1,523,786 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC7A7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl776,198,256 - 76,235,402 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1776,195,774 - 76,235,406 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2781,437,332 - 81,474,660 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SLC7A7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12923,135,583 - 23,183,472 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2923,139,267 - 23,180,966 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605923,241,283 - 23,287,260 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc7a7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248209,708,482 - 9,757,251 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248209,692,057 - 9,757,251 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Slc7a7
863 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:221
Count of miRNA genes:152
Interacting mature miRNAs:160
Transcripts:ENSRNOT00000014391
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331729Rf42Renal function QTL 423.071kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)151736289773690657Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15142356671Rat
10755503Bp391Blood pressure QTL 3912.37arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)152024860037896129Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)152280624098288169Rat
9589149Insul29Insulin level QTL 299.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)15134723002Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)152280624098288169Rat
10401805Kidm51Kidney mass QTL 51kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1530632945306329Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151249614165205939Rat
2298549Neuinf12Neuroinflammation QTL 123.5nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)15155302115Rat
8552920Pigfal8Plasma insulin-like growth factor 1 level QTL 83blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)15134723002Rat
2293688Bss29Bone structure and strength QTL 295.310.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)151111114256111142Rat
5685002Bss103Bone structure and strength QTL 1032.8tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)151448116528469888Rat
8694361Abfw6Abdominal fat weight QTL 610.20.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)15134723002Rat
631273Lecl2Lens clarity QTL 20.001lens clarity trait (VT:0001304)age of onset/diagnosis of cataract (CMO:0001584)151059608955596089Rat
2300167Bmd63Bone mineral density QTL 635.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)151111114256111142Rat
731170Pur3Proteinuria QTL 32.30.0005urine protein amount (VT:0005160)urine protein excretion rate (CMO:0000759)15141686771Rat
738017Hcas7Hepatocarcinoma susceptibility QTL 72.91liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)15226636846921453Rat
10054130Srcrt8Stress Responsive Cort QTL 82.180.0085blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)152211793367117933Rat
2300173Bmd62Bone mineral density QTL 6212.80.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)151111114256111142Rat
2324620Coatc3Coat color QTL 3coat/hair pigmentation trait (VT:0010463)pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)151985656646187442Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151672552880672115Rat
1582251Gluco24Glucose level QTL 243.20.0008blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)15553075650530756Rat
1354657Despr13Despair related QTL 130.0022locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)15129912054Rat
631550Bw7Body weight QTL 73.6body mass (VT:0001259)body weight (CMO:0000012)151985656634924750Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)152280624098288169Rat

Markers in Region
RH139134  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21527,850,253 - 27,850,503 (+)MAPPERmRatBN7.2
Rnor_6.01533,041,516 - 33,041,765NCBIRnor6.0
Rnor_5.01536,922,421 - 36,922,670UniSTSRnor5.0
RGSC_v3.41532,459,910 - 32,460,159UniSTSRGSC3.4
Celera1527,431,056 - 27,431,305UniSTS
Cytogenetic Map15p13UniSTS
RH142879  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21527,850,471 - 27,850,599 (+)MAPPERmRatBN7.2
Rnor_6.01533,041,734 - 33,041,861NCBIRnor6.0
Rnor_5.01536,922,639 - 36,922,766UniSTSRnor5.0
RGSC_v3.41532,460,128 - 32,460,255UniSTSRGSC3.4
Celera1527,431,274 - 27,431,401UniSTS
Cytogenetic Map15p13UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_031341 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006252020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006252023 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006252024 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008770705 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017599807 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017599808 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017599809 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039093692 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039093693 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039093694 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039093695 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039093696 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039093698 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039093699 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274696 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274698 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB020520 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC114835 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF200684 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC078797 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC091142 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474049 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000014391   ⟹   ENSRNOP00000014391
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1527,822,091 - 27,865,648 (-)Ensembl
Rnor_6.0 Ensembl1533,013,504 - 33,051,129 (-)Ensembl
RefSeq Acc Id: NM_031341   ⟹   NP_112631
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81531,792,125 - 31,835,683 (-)NCBI
mRatBN7.21527,822,091 - 27,865,653 (-)NCBI
Rnor_6.01533,013,356 - 33,052,297 (-)NCBI
Rnor_5.01536,894,258 - 36,945,548 (-)NCBI
RGSC_v3.41532,431,748 - 32,471,526 (-)RGD
Celera1527,403,911 - 27,448,739 (-)RGD
Sequence:
RefSeq Acc Id: XM_006252020   ⟹   XP_006252082
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81531,792,122 - 31,835,917 (-)NCBI
mRatBN7.21527,822,088 - 27,865,888 (-)NCBI
Rnor_6.01533,013,346 - 33,052,317 (-)NCBI
Rnor_5.01536,894,258 - 36,945,548 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006252023   ⟹   XP_006252085
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81531,792,122 - 31,834,839 (-)NCBI
mRatBN7.21527,822,088 - 27,864,810 (-)NCBI
Rnor_6.01533,013,346 - 33,051,428 (-)NCBI
Rnor_5.01536,894,258 - 36,945,548 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008770705   ⟹   XP_008768927
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81531,792,122 - 31,843,149 (-)NCBI
mRatBN7.21527,822,088 - 27,873,121 (-)NCBI
Rnor_6.01533,013,346 - 33,059,733 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039093692   ⟹   XP_038949620
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81531,792,122 - 31,843,148 (-)NCBI
mRatBN7.21527,822,088 - 27,873,121 (-)NCBI
RefSeq Acc Id: XM_039093693   ⟹   XP_038949621
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81531,792,122 - 31,842,630 (-)NCBI
mRatBN7.21527,822,088 - 27,872,850 (-)NCBI
RefSeq Acc Id: XM_039093694   ⟹   XP_038949622
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81531,792,122 - 31,835,997 (-)NCBI
mRatBN7.21527,822,088 - 27,865,964 (-)NCBI
RefSeq Acc Id: XM_039093695   ⟹   XP_038949623
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81531,792,122 - 31,838,184 (-)NCBI
mRatBN7.21527,822,088 - 27,868,154 (-)NCBI
RefSeq Acc Id: XM_039093696   ⟹   XP_038949624
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81531,792,122 - 31,837,215 (-)NCBI
mRatBN7.21527,822,088 - 27,866,638 (-)NCBI
RefSeq Acc Id: XM_039093698   ⟹   XP_038949626
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81531,792,122 - 31,834,508 (-)NCBI
mRatBN7.21527,822,088 - 27,873,119 (-)NCBI
RefSeq Acc Id: XM_039093699   ⟹   XP_038949627
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81531,792,122 - 31,834,498 (-)NCBI
mRatBN7.21527,822,088 - 27,864,471 (-)NCBI
RefSeq Acc Id: XM_063274696   ⟹   XP_063130766
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81531,792,122 - 31,852,732 (-)NCBI
RefSeq Acc Id: XM_063274698   ⟹   XP_063130768
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81531,792,122 - 31,801,778 (-)NCBI
RefSeq Acc Id: NP_112631   ⟸   NM_031341
- UniProtKB: Q9QZ66 (UniProtKB/Swiss-Prot),   Q9R0S5 (UniProtKB/Swiss-Prot),   A6KGT1 (UniProtKB/TrEMBL),   A6KGS5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006252082   ⟸   XM_006252020
- Peptide Label: isoform X1
- UniProtKB: Q9QZ66 (UniProtKB/Swiss-Prot),   Q9R0S5 (UniProtKB/Swiss-Prot),   A6KGT1 (UniProtKB/TrEMBL),   A6KGS5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006252085   ⟸   XM_006252023
- Peptide Label: isoform X1
- UniProtKB: Q9QZ66 (UniProtKB/Swiss-Prot),   Q9R0S5 (UniProtKB/Swiss-Prot),   A6KGT1 (UniProtKB/TrEMBL),   A6KGS5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008768927   ⟸   XM_008770705
- Peptide Label: isoform X1
- UniProtKB: Q9QZ66 (UniProtKB/Swiss-Prot),   Q9R0S5 (UniProtKB/Swiss-Prot),   A6KGT1 (UniProtKB/TrEMBL),   A6KGS5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000014391   ⟸   ENSRNOT00000014391
RefSeq Acc Id: XP_038949620   ⟸   XM_039093692
- Peptide Label: isoform X1
- UniProtKB: Q9R0S5 (UniProtKB/Swiss-Prot),   Q9QZ66 (UniProtKB/Swiss-Prot),   A6KGT1 (UniProtKB/TrEMBL),   A6KGS5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038949626   ⟸   XM_039093698
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038949621   ⟸   XM_039093693
- Peptide Label: isoform X1
- UniProtKB: Q9R0S5 (UniProtKB/Swiss-Prot),   Q9QZ66 (UniProtKB/Swiss-Prot),   A6KGT1 (UniProtKB/TrEMBL),   A6KGS5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038949623   ⟸   XM_039093695
- Peptide Label: isoform X1
- UniProtKB: Q9R0S5 (UniProtKB/Swiss-Prot),   Q9QZ66 (UniProtKB/Swiss-Prot),   A6KGT1 (UniProtKB/TrEMBL),   A6KGS5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038949624   ⟸   XM_039093696
- Peptide Label: isoform X1
- UniProtKB: Q9R0S5 (UniProtKB/Swiss-Prot),   Q9QZ66 (UniProtKB/Swiss-Prot),   A6KGT1 (UniProtKB/TrEMBL),   A6KGS5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038949622   ⟸   XM_039093694
- Peptide Label: isoform X1
- UniProtKB: Q9R0S5 (UniProtKB/Swiss-Prot),   Q9QZ66 (UniProtKB/Swiss-Prot),   A6KGT1 (UniProtKB/TrEMBL),   A6KGS5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038949627   ⟸   XM_039093699
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063130766   ⟸   XM_063274696
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063130768   ⟸   XM_063274698
- Peptide Label: isoform X2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9R0S5-F1-model_v2 AlphaFold Q9R0S5 1-512 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:619902 AgrOrtholog
BioCyc Gene G2FUF-13807 BioCyc
Ensembl Genes ENSRNOG00000010296 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000014391 ENTREZGENE
  ENSRNOT00000014391.6 UniProtKB/Swiss-Prot
Gene3D-CATH Amino acid/polyamine transporter I UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7129657 IMAGE-MGC_LOAD
InterPro AA/rel_permease1 UniProtKB/Swiss-Prot
  AminoAcid_Transporter UniProtKB/Swiss-Prot
KEGG Report rno:83509 UniProtKB/Swiss-Prot
MGC_CLONE MGC:108661 IMAGE-MGC_LOAD
NCBI Gene 83509 ENTREZGENE
PANTHER AMINO ACID TRANSPORTER UniProtKB/Swiss-Prot
  Y+L AMINO ACID TRANSPORTER 1 UniProtKB/Swiss-Prot
Pfam AA_permease_2 UniProtKB/Swiss-Prot
PhenoGen Slc7a7 PhenoGen
PIRSF AA_transporter UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000010296 RatGTEx
UniProt A6KGS5 ENTREZGENE, UniProtKB/TrEMBL
  A6KGS7_RAT UniProtKB/TrEMBL
  A6KGT1 ENTREZGENE, UniProtKB/TrEMBL
  Q9QZ66 ENTREZGENE
  Q9R0S5 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q9QZ66 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-09 Slc7a7  solute carrier family 7 member 7  Slc7a7  solute carrier family 7 (amino acid transporter light chain, y+L system), member 7  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-08-01 Slc7a7  solute carrier family 7 (amino acid transporter light chain, y+L system), member 7  Slc7a7  solute carrier family 7 (cationic amino acid transporter, y+ system), member 7  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Slc7a7  solute carrier family 7 (cationic amino acid transporter, y+ system), member 7    solute carrier family 7 (cationic amino acid transporter, y+system), member 7  Name updated 1299863 APPROVED
2002-08-07 Slc7a7  solute carrier family 7 (cationic amino acid transporter, y+system), member 7      Symbol and Name status set to provisional 70820 PROVISIONAL