Gene: Slc20a2 (solute carrier family 20 member 2) Rattus norvegicus
Analyze
Symbol:
Slc20a2
Name:
solute carrier family 20 member 2
RGD ID:
3699
Description:
Predicted to have inorganic phosphate transmembrane transporter activity. Predicted to be involved in phosphate ion transmembrane transport. Predicted to localize to integral component of plasma membrane. Human ortholog(s) of this gene implicated in basal ganglia calcification. Orthologous to human SLC20A2 (solute carrier family 20 member 2); PARTICIPATES IN phosphate transport pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 6-propyl-2-thiouracil.
Type:
protein-coding
RefSeq Status:
PROVISIONAL
Also known as:
Ab1-188; gibbon ape leukemia virus receptor 2; Glvr2; phosphate transporter 2; Pit-2; RAM-1; Ram1; receptor for amphitropic viruses 1; receptor for amphotropic viruses 1; sodium-dependent phosphate transporter 2; solute carrier family 20 (phosphate transporter), member 2; solute carrier family 20, member 2
Orthologs:
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
SLC20A2 (solute carrier family 20 member 2) HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):
Slc20a2 (solute carrier family 20, member 2) HGNC
Treefam, EggNOG, NCBI, OMA, HomoloGene, Inparanoid, Panther, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):
Slc20a2 (solute carrier family 20 member 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
SLC20A2 (solute carrier family 20 member 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
SLC20A2 (solute carrier family 20 member 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Slc20a2 (solute carrier family 20 member 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
SLC20A2 (solute carrier family 20 member 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):
SLC20A2 (solute carrier family 20 member 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Slc20a2 (solute carrier family 20 member 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Alliance orthologs 3
Homo sapiens (human):
SLC20A2 (solute carrier family 20 member 2)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|TreeFam)
Mus musculus (house mouse):
Slc20a2 (solute carrier family 20, member 2)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|TreeFam)
Danio rerio (zebrafish):
slc20a2 (solute carrier family 20 member 2)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|TreeFam)
Saccharomyces cerevisiae (baker's yeast):
PHO89
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|TreeFam)
Drosophila melanogaster (fruit fly):
NaPi-III
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|TreeFam)
Caenorhabditis elegans (roundworm):
pitr-1
Alliance
DIOPT (Ensembl Compara|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB)
Caenorhabditis elegans (roundworm):
pitr-2
Alliance
DIOPT (Hieranoid|InParanoid|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|TreeFam)
Caenorhabditis elegans (roundworm):
pitr-3
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|TreeFam)
Caenorhabditis elegans (roundworm):
pitr-4
Alliance
DIOPT (Ensembl Compara|OMA|OrthoFinder|OrthoInspector|PANTHER|TreeFam)
Caenorhabditis elegans (roundworm):
pitr-5
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|TreeFam)
Caenorhabditis elegans (roundworm):
pitr-6
Alliance
DIOPT (Ensembl Compara|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|TreeFam)
Latest Assembly:
Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information:
Annotation category: suggests misassembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Rnor_6.0 16 74,318,287 - 74,408,030 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 16 74,317,899 - 74,408,030 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 16 73,949,883 - 74,042,911 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 16 73,948,917 - 74,174,391 (-) NCBI RGSC3.4 rn4 RGSC3.4 RGSC_v3.1 16 73,949,185 - 74,174,656 (-) NCBI Celera 16 67,353,947 - 67,441,733 (-) NCBI Celera Cytogenetic Map 16 q12.5 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Imported Annotations - CTD
basal ganglia disease ISO RGD:733735 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:25938945 calcinosis ISO RGD:733735 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:25938945 Idiopathic Basal Ganglia Calcification 1 ISO RGD:733735 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:22327515
Imported Annotations - MGI
basal ganglia calcification ISS RGD:736588 13592920 OMIM:114100 more ... MouseDO Imported Annotations - OMIM
Idiopathic Basal Ganglia Calcification 1 ISO RGD:733735 7240710 OMIM
1,2-dimethylhydrazine increases expression ISO RGD:736588 6480464 1, 2-Dimethylhydrazine results in increased expression of SLC20A2 mRNA CTD PMID:22206623 17alpha-ethynylestradiol multiple interactions ISO RGD:736588 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SLC20A2 mRNA CTD PMID:17942748 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:733735 6480464 Tetrachlorodibenzodioxin results in increased expression of SLC20A2 mRNA CTD PMID:20106945 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of SLC20A2 mRNA CTD PMID:20959002 , PMID:21215274 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of SLC20A2 mRNA CTD PMID:22298810 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:736588 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SLC20A2 mRNA CTD PMID:17942748 2,4-dinitrotoluene affects expression EXP 6480464 2, 4-dinitrotoluene affects the expression of SLC20A2 mRNA CTD PMID:21346803 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of SLC20A2 mRNA CTD PMID:24780913 acetamide decreases expression EXP 6480464 acetamide results in decreased expression of SLC20A2 mRNA CTD PMID:31881176 aflatoxin B1 increases expression ISO RGD:736588 6480464 Aflatoxin B1 results in increased expression of SLC20A2 mRNA CTD PMID:19770486 aflatoxin B1 increases methylation ISO RGD:733735 6480464 Aflatoxin B1 results in increased methylation of SLC20A2 intron CTD PMID:30157460 aflatoxin B1 decreases methylation ISO RGD:733735 6480464 Aflatoxin B1 results in decreased methylation of SLC20A2 gene CTD PMID:27153756 antirheumatic drug increases expression ISO RGD:733735 6480464 Antirheumatic Agents results in increased expression of SLC20A2 mRNA CTD PMID:24449571 arsane affects methylation ISO RGD:733735 6480464 Arsenic affects the methylation of SLC20A2 gene CTD PMID:25304211 arsenic atom affects methylation ISO RGD:733735 6480464 Arsenic affects the methylation of SLC20A2 gene CTD PMID:25304211 benzo[a]pyrene decreases expression ISO RGD:733735 6480464 Benzo(a)pyrene results in decreased expression of SLC20A2 mRNA CTD PMID:20064835 , PMID:32234424 benzo[a]pyrene affects methylation ISO RGD:733735 6480464 Benzo(a)pyrene affects the methylation of SLC20A2 5' UTR CTD PMID:27901495 benzo[a]pyrene increases expression ISO RGD:736588 6480464 Benzo(a)pyrene results in increased expression of SLC20A2 mRNA CTD PMID:19770486 benzo[e]pyrene increases methylation ISO RGD:733735 6480464 benzo(e)pyrene results in increased methylation of SLC20A2 intron CTD PMID:30157460 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of SLC20A2 mRNA CTD PMID:25181051 C60 fullerene decreases expression EXP 6480464 fullerene C60 results in decreased expression of SLC20A2 mRNA CTD PMID:19167457 cadmium atom increases expression ISO RGD:733735 6480464 Cadmium results in increased expression of SLC20A2 mRNA CTD PMID:23369406 cadmium dichloride affects expression ISO RGD:736588 6480464 Cadmium Chloride affects the expression of SLC20A2 mRNA CTD PMID:20883709 carbon nanotube increases expression ISO RGD:736588 6480464 Nanotubes, Carbon analog results in increased expression of SLC20A2 mRNA, Nanotubes, Carbon results in increased expression of SLC20A2 mRNA CTD PMID:25554681 , PMID:25620056 choline multiple interactions ISO RGD:733735 6480464 Choline promotes the reaction [SLC20A2 protein results in increased uptake of Phosphates] CTD PMID:17494632 cocaine affects expression EXP 6480464 Cocaine affects the expression of SLC20A2 mRNA CTD PMID:20187946 copper(II) sulfate increases expression ISO RGD:733735 6480464 Copper Sulfate results in increased expression of SLC20A2 mRNA CTD PMID:19549813 cyclosporin A decreases expression ISO RGD:733735 6480464 Cyclosporine results in decreased expression of SLC20A2 mRNA CTD PMID:20106945 , PMID:25562108 dicrotophos increases expression ISO RGD:733735 6480464 dicrotophos results in increased expression of SLC20A2 mRNA CTD PMID:28302478 dorsomorphin multiple interactions ISO RGD:733735 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SLC20A2 mRNA CTD PMID:27188386 endosulfan increases expression EXP 6480464 Endosulfan results in increased expression of SLC20A2 mRNA CTD PMID:29391264 ethanol increases expression EXP 6480464 Ethanol results in increased expression of SLC20A2 mRNA CTD PMID:15353170 ethanol increases expression ISO RGD:736588 6480464 Ethanol results in increased expression of SLC20A2 mRNA CTD PMID:30319688 flavonoids decreases expression EXP 6480464 Flavonoids results in decreased expression of SLC20A2 mRNA CTD PMID:18035473 flutamide increases expression EXP 6480464 Flutamide results in increased expression of SLC20A2 mRNA CTD PMID:24136188 folic acid decreases expression ISO RGD:736588 6480464 Folic Acid results in decreased expression of SLC20A2 mRNA CTD PMID:25629700 furan increases methylation EXP 6480464 furan results in increased methylation of SLC20A2 gene CTD PMID:22079235 ketamine increases expression EXP 6480464 Ketamine results in increased expression of SLC20A2 mRNA CTD PMID:20080153 leflunomide increases expression ISO RGD:733735 6480464 leflunomide results in increased expression of SLC20A2 mRNA CTD PMID:28988120 lithium atom multiple interactions ISO RGD:733735 6480464 Lithium promotes the reaction [SLC20A2 protein results in increased uptake of Phosphates] CTD PMID:17494632 lithium hydride multiple interactions ISO RGD:733735 6480464 Lithium promotes the reaction [SLC20A2 protein results in increased uptake of Phosphates] CTD PMID:17494632 menadione affects expression ISO RGD:733735 6480464 Vitamin K 3 affects the expression of SLC20A2 mRNA CTD PMID:20044591 methapyrilene increases methylation ISO RGD:733735 6480464 Methapyrilene results in increased methylation of SLC20A2 intron CTD PMID:30157460 methapyrilene decreases expression EXP 6480464 Methapyrilene results in decreased expression of SLC20A2 mRNA CTD PMID:30467583 paracetamol affects expression ISO RGD:736588 6480464 Acetaminophen affects the expression of SLC20A2 mRNA CTD PMID:17562736 phenethyl isothiocyanate increases expression EXP 6480464 phenethyl isothiocyanate results in increased expression of SLC20A2 mRNA CTD PMID:17616710 phenylmercury acetate multiple interactions ISO RGD:733735 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SLC20A2 mRNA CTD PMID:27188386 phosphonoformic acid multiple interactions ISO RGD:733735 6480464 Foscarnet inhibits the reaction [Phosphates results in increased expression of SLC20A2 mRNA] CTD PMID:23308213 pirinixic acid increases expression ISO RGD:736588 6480464 pirinixic acid results in increased expression of SLC20A2 mRNA CTD PMID:17426115 propiconazole decreases expression ISO RGD:736588 6480464 propiconazole results in decreased expression of SLC20A2 mRNA CTD PMID:21278054 rifampicin decreases expression ISO RGD:733735 6480464 Rifampin results in decreased expression of SLC20A2 mRNA CTD PMID:27199754 SB 431542 multiple interactions ISO RGD:733735 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SLC20A2 mRNA CTD PMID:27188386 silver atom increases expression ISO RGD:733735 6480464 Silver results in increased expression of SLC20A2 mRNA CTD PMID:28959546 silver(0) increases expression ISO RGD:733735 6480464 Silver results in increased expression of SLC20A2 mRNA CTD PMID:28959546 sodium arsenate decreases expression ISO RGD:736588 6480464 sodium arsenate results in decreased expression of SLC20A2 mRNA CTD PMID:30953684 sodium arsenite increases expression ISO RGD:733735 6480464 sodium arsenite results in increased expression of SLC20A2 mRNA CTD PMID:16966095 sodium arsenite increases expression ISO RGD:736588 6480464 sodium arsenite results in increased expression of SLC20A2 mRNA CTD PMID:20883709 sodium atom multiple interactions ISO RGD:733735 6480464 Sodium promotes the reaction [SLC20A2 protein results in increased uptake of Phosphates] CTD PMID:17494632 streptozocin increases expression ISO RGD:736588 6480464 Streptozocin results in increased expression of SLC20A2 mRNA, Streptozocin results in increased expression of SLC20A2 protein CTD PMID:29216956 streptozocin multiple interactions ISO RGD:736588 6480464 INS1 protein inhibits the reaction [Streptozocin results in increased expression of SLC20A2 mRNA], INS1 protein inhibits the reaction [Streptozocin results in increased expression of SLC20A2 protein] CTD PMID:29216956 succimer multiple interactions ISO RGD:736588 6480464 [Succimer binds to Magnetite Nanoparticles] which results in increased expression of SLC20A2 mRNA CTD PMID:21641980 sunitinib decreases expression ISO RGD:733735 6480464 Sunitinib results in decreased expression of SLC20A2 mRNA CTD PMID:31533062 tetrachloromethane affects expression ISO RGD:736588 6480464 Carbon Tetrachloride affects the expression of SLC20A2 mRNA CTD PMID:17484886 thioacetamide decreases expression EXP 6480464 Thioacetamide results in decreased expression of SLC20A2 mRNA CTD PMID:23411599 triclosan decreases expression ISO RGD:733735 6480464 Triclosan results in decreased expression of SLC20A2 mRNA CTD PMID:30510588 urethane decreases expression ISO RGD:733735 6480464 Urethane results in decreased expression of SLC20A2 mRNA CTD PMID:28818685 valproic acid decreases expression ISO RGD:736588 6480464 Valproic Acid analog results in decreased expression of SLC20A2 mRNA, Valproic Acid results in decreased expression of SLC20A2 mRNA CTD PMID:19136453 , PMID:21427059 valproic acid increases methylation ISO RGD:733735 6480464 Valproic Acid results in increased methylation of SLC20A2 gene CTD PMID:29154799 vinclozolin decreases expression EXP 6480464 vinclozolin results in decreased expression of SLC20A2 mRNA CTD PMID:23034163 zidovudine increases expression ISO RGD:733735 6480464 Zidovudine results in increased expression of SLC20A2 mRNA CTD PMID:24292225
Gene-Chemical Interaction Annotations
