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Gene: Mvd (mevalonate diphosphate decarboxylase) Rattus norvegicus
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Symbol: Mvd
Name: mevalonate diphosphate decarboxylase
Description: Exhibits diphosphomevalonate decarboxylase activity. Involved in isopentenyl diphosphate biosynthetic process, mevalonate pathway and response to drug. Localizes to the cytosol and peroxisomal matrix. Human ortholog(s) of this gene implicated in porokeratosis. Orthologous to human MVD (mevalonate diphosphate decarboxylase); PARTICIPATES IN alendronate pharmacodynamics pathway; cholesterol biosynthetic pathway; cholesterol ester storage disease pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: diphosphomevalonate decarboxylase; MDDase; mevalonate (diphospho) decarboxylase; mevalonate pyrophosphate decarboxylase; Mvpd
Orthologs:
Homo sapiens (human) : MVD (mevalonate diphosphate decarboxylase)  HGNC  Alliance
Mus musculus (house mouse) : Mvd (mevalonate (diphospho) decarboxylase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mvd (mevalonate diphosphate decarboxylase)
Pan paniscus (bonobo/pygmy chimpanzee) : MVD (mevalonate diphosphate decarboxylase)
Canis lupus familiaris (dog) : MVD (mevalonate diphosphate decarboxylase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mvd (mevalonate diphosphate decarboxylase)
Sus scrofa (pig) : MVD (mevalonate diphosphate decarboxylase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01955,258,910 - 55,268,933 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1955,258,905 - 55,268,951 (-)Ensembl
Rnor_5.01965,967,921 - 65,978,403 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41952,722,306 - 52,732,312 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11952,727,186 - 52,737,193 (-)NCBI
Celera1949,735,851 - 49,745,874 (-)NCBICelera
Cytogenetic Map19q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Mvd
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621292
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.