Ankrd1 (ankyrin repeat domain 1) - Rat Genome Database

Name: Ankrd1
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Ankrd1 (ankyrin repeat domain 1) Rattus norvegicus

Analyze

Symbol:

Ankrd1

Name:

ankyrin repeat domain 1

RGD ID:

61989

Description:

Predicted to enable several functions, including R-SMAD binding activity; histone deacetylase binding activity; and p53 binding activity. Involved in several processes, including cellular response to hypoxia; negative regulation of transcription by RNA polymerase II; and positive regulation of neuron projection development. Located in I band and nucleus. Human ortholog(s) of this gene implicated in congenital structural myopathy; dilated cardiomyopathy; hypertrophic cardiomyopathy; nemaline myopathy; and spinal muscular atrophy. Orthologous to human ANKRD1 (ankyrin repeat domain 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Also known as:

Alrp; ankyrin repeat domain 1 (cardiac muscle); ankyrin repeat domain-containing protein 1; ankyrin-like repeat protein; cardiac adriamycin-responsive protein; cardiac ankyrin repeat protein; cardiac responsive adriamycin protein; Carp; Crap; LOC102552909; MARP; muscle ankyrin repeat protein; uncharacterized LOC102552909

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ANKRD1 (ankyrin repeat domain 1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Ankrd1 (ankyrin repeat domain 1 (cardiac muscle))	HGNC	Treefam, EggNOG, OrthoMCL, NCBI, OMA, HomoloGene, Inparanoid, Panther, PhylomeDB, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):	Ankrd1 (ankyrin repeat domain 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ANKRD1 (ankyrin repeat domain 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ANKRD1 (ankyrin repeat domain 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ankrd1 (ankyrin repeat domain 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ANKRD1 (ankyrin repeat domain 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ANKRD1 (ankyrin repeat domain 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ankrd1 (ankyrin repeat domain 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	ANKRD2 (ankyrin repeat domain 2)	HGNC	OrthoDB
Homo sapiens (human):	ANKRD23 (ankyrin repeat domain 23)	HGNC	OrthoDB
Alliance orthologs ³
Mus musculus (house mouse):	Ankrd1 (ankyrin repeat domain 1 (cardiac muscle))	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Homo sapiens (human):	ANKRD1 (ankyrin repeat domain 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Danio rerio (zebrafish):	ankrd1a (ankyrin repeat domain 1a (cardiac muscle))	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	1	233,815,851 - 233,834,891 (-)	NCBI	mRatBN7.2
mRatBN7.2 Ensembl	1	233,815,851 - 233,834,919 (-)	Ensembl
Rnor_6.0	1	254,726,985 - 254,745,673 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	254,726,969 - 254,735,548 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	262,038,137 - 262,046,691 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	240,316,123 - 240,324,804 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	1	240,490,005 - 240,498,684 (-)	NCBI
Celera	1	230,914,960 - 230,923,398 (-)	NCBI		Celera
Cytogenetic Map	1	q53	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Brugada syndrome (ISO)

Cardiomegaly (IDA)

cardiomyopathy (ISO)

congenital structural myopathy (ISO)

dilated cardiomyopathy (ISO)

dilated cardiomyopathy 1A (ISO)

dilated cardiomyopathy 1H (ISO)

endometriosis (ISO)

familial hypertrophic cardiomyopathy (ISO)

hypertrophic cardiomyopathy (ISO)

hypertrophic cardiomyopathy 1 (ISO)

left ventricular noncompaction (ISO)

long QT syndrome (ISO)

Myocardial Reperfusion Injury (IEP)

nemaline myopathy (ISO)

scimitar syndrome (ISO)

Spinal Cord Injuries (IEP)

spinal muscular atrophy (ISO)

systolic heart failure (ISO)

Wounds and Injuries (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,1-dichloroethene (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

3,4-methylenedioxymethamphetamine (ISO)

4,4'-sulfonyldiphenol (ISO)

5-fluorouracil (ISO)

6-propyl-2-thiouracil (EXP)

aflatoxin B1 (ISO)

amitriptyline (EXP)

ammonium chloride (EXP)

amphetamine (EXP)

ampicillin (ISO)

andrographolide (ISO)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

beta-naphthoflavone (ISO)

bis(2-chloroethyl) sulfide (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

bleomycin A2 (ISO)

Botulinum toxin type A (EXP)

bromobenzene (EXP)

butanal (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

cadmium sulfate (ISO)

carbon nanotube (ISO)

carmustine (ISO)

chlordecone (ISO)

choline (ISO)

cisplatin (EXP,ISO)

cobalt dichloride (EXP,ISO)

copper(II) chloride (ISO)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

cylindrospermopsin (ISO)

daunorubicin (EXP)

dexamethasone (ISO)

dibutyl phthalate (ISO)

dimethylarsinous acid (ISO)

dioxygen (ISO)

diquat (ISO)

dorsomorphin (ISO)

doxorubicin (EXP,ISO)

Echimidine (EXP)

endosulfan (EXP)

ethanol (ISO)

fenvalerate (EXP)

folic acid (ISO)

formaldehyde (ISO)

geldanamycin (ISO)

gemcitabine (ISO)

gentamycin (EXP)

Heliotrine (EXP)

hydrogen peroxide (ISO)

L-methionine (ISO)

leflunomide (ISO)

Licochalcone B (ISO)

lipopolysaccharide (ISO)

mercury dibromide (ISO)

methylisothiazolinone (ISO)

Muraglitazar (EXP)

nickel sulfate (ISO)

nitrofen (EXP)

O-methyleugenol (ISO)

p-chloromercuribenzoic acid (ISO)

panobinostat (ISO)

paracetamol (EXP,ISO)

perfluorooctanoic acid (ISO)

phenobarbital (ISO)

phenylmercury acetate (ISO)

pirinixic acid (ISO)

Platyphylline (EXP)

propanal (ISO)

quinolin-8-ol (ISO)

raloxifene (ISO)

resveratrol (ISO)

rotenone (ISO)

SB 431542 (ISO)

senecionine (EXP)

silicon dioxide (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenite (ISO)

stigmasterol (ISO)

streptozocin (EXP)

sunitinib (ISO)

tacrolimus hydrate (ISO)

tamoxifen (ISO)

temozolomide (ISO)

titanium dioxide (ISO)

triadimefon (ISO)

trichloroethene (EXP,ISO)

trichostatin A (ISO)

tris(2-butoxyethyl) phosphate (ISO)

troglitazone (EXP)

tunicamycin (ISO)

urethane (ISO)

valproic acid (ISO)

vanadyl sulfate (EXP)

verteporfin (ISO)

vorinostat (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cardiac muscle tissue morphogenesis (ISO)

cellular response to hypoxia (IEP)

cellular response to interleukin-1 (ISO)

cellular response to lipopolysaccharide (ISO)

cellular response to mechanical stimulus (ISO)

cellular response to organic cyclic compound (IEP)

cellular response to transforming growth factor beta stimulus (ISO)

cellular response to tumor necrosis factor (ISO)

cellular response to xenobiotic stimulus (ISO)

negative regulation of DNA biosynthetic process (ISO)

negative regulation of transcription by RNA polymerase II (IDA)

negative regulation of transcription, DNA-templated (TAS)

positive regulation of apoptotic process (ISO)

positive regulation of DNA damage response, signal transduction by p53 class mediator (ISO)

positive regulation of neuron projection development (IMP)

positive regulation of protein secretion (ISO)

positive regulation of transcription, DNA-templated (IEA)

protein kinase C signaling (ISO)

regulation of transcription by RNA polymerase II (IBA,ISO)

response to muscle stretch (ISO)

skeletal muscle cell differentiation (ISO)

Cellular Component

cytoplasm (ISO)

cytosol (ISO)

fibrillar center (IEA,ISO)

I band (IDA,ISO)

myofibril (ISO)

nucleoplasm (IEA,ISO)

nucleus (IBA,IDA,ISO,TAS)

perinuclear region of cytoplasm (ISO)

protein-containing complex (ISO)

transcription regulator complex (ISO)

Molecular Function

actin binding (ISO)

DNA binding (ISO)

histone deacetylase binding (ISO)

p53 binding (ISO)

protein binding (IPI,ISO)

R-SMAD binding (ISO)

RNA polymerase II-specific DNA-binding transcription factor binding (IBA,ISO)

titin binding (ISO)

transcription coactivator activity (ISO)

transcription coregulator activity (TAS)

transcription corepressor activity (ISO)

transcription factor binding (IPI)

References

References - curated


1.	Aihara Y, etal., Hypertension. 2000 Jul;36(1):48-53.
2.	Aihara Y, etal., J Mol Cell Cardiol. 2000 Aug;32(8):1401-14.
3.	Arimura T, etal., J Am Coll Cardiol. 2009 Jul 21;54(4):334-42.
4.	Bang ML, etal., J Cell Biol. 2001 Apr 16;153(2):413-27.
5.	Duboscq-Bidot L, etal., Eur Heart J. 2009 Sep;30(17):2128-36. Epub 2009 Jun 12.
6.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
7.	GOA data from the GO Consortium
8.	Han XJ, etal., J Biol Chem. 2005 Jun 17;280(24):23122-9. Epub 2005 Apr 12.
9.	Lee MJ, etal., Exp Mol Med. 2009 Apr 30;41(4):243-52.
10.	MGD data from the GO Consortium
11.	Munro E, Eur J Vasc Endovasc Surg. 1998 Aug;16(2):170-1.
12.	Nakada C, etal., Pathol Int. 2003 Oct;53(10):653-8.
13.	RGD automated data pipeline
14.	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
15.	RGD automated import pipeline for gene-chemical interactions
16.	Shi Y, etal., Am J Pathol. 2005 Jan;166(1):303-12.
17.	Stam FJ, etal., Eur J Neurosci. 2007 Jun;25(12):3629-37.
18.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
19.	Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
20.	Uys GM, etal., BMC Cell Biol. 2011 May 10;12:18. doi: 10.1186/1471-2121-12-18.
21.	Zou Y, etal., Development. 1997 Feb;124(4):793-804.

Additional References at PubMed

PMID:7730328	PMID:9278441	PMID:9382869	PMID:11139470	PMID:12054667	PMID:14583192	PMID:14741210	PMID:15489334	PMID:15698842	PMID:15805281	PMID:16322914	PMID:17239933
PMID:18310072	PMID:19500504	PMID:19608030	PMID:20599664	PMID:22147266	PMID:22532871	PMID:22892129	PMID:23811403	PMID:25089522	PMID:27353086

Genomics

Comparative Map Data

Ankrd1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	1	233,815,851 - 233,834,891 (-)	NCBI	mRatBN7.2
mRatBN7.2 Ensembl	1	233,815,851 - 233,834,919 (-)	Ensembl
Rnor_6.0	1	254,726,985 - 254,745,673 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	254,726,969 - 254,735,548 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	262,038,137 - 262,046,691 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	240,316,123 - 240,324,804 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	1	240,490,005 - 240,498,684 (-)	NCBI
Celera	1	230,914,960 - 230,923,398 (-)	NCBI		Celera
Cytogenetic Map	1	q53	NCBI

ANKRD1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	10	90,912,096 - 90,921,087 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	10	90,912,096 - 90,921,087 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	10	92,671,853 - 92,680,844 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	10	92,661,837 - 92,671,012 (-)	NCBI	NCBI36		hg18	NCBI36
Build 34	10	92,661,836 - 92,671,012	NCBI
Celera	10	86,418,314 - 86,427,472 (-)	NCBI
Cytogenetic Map	10	q23.31	NCBI
HuRef	10	86,300,878 - 86,309,941 (-)	NCBI		HuRef
CHM1_1	10	92,949,704 - 92,958,879 (-)	NCBI		CHM1_1

Ankrd1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	19	36,089,365 - 36,097,244 (-)	NCBI	GRCm39		mm39
GRCm39 Ensembl	19	36,089,361 - 36,097,499 (-)	Ensembl
GRCm38	19	36,111,965 - 36,119,844 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	19	36,111,961 - 36,120,099 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	19	36,186,455 - 36,194,334 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	19	36,177,109 - 36,184,988 (-)	NCBI			mm8
Celera	19	36,887,384 - 36,895,221 (-)	NCBI		Celera
Cytogenetic Map	19	C2	NCBI

Ankrd1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955425	2,258,392 - 2,267,878 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955425	2,258,554 - 2,267,699 (+)	NCBI	ChiLan1.0	ChiLan1.0

ANKRD1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	10	91,179,325 - 91,188,414 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	10	91,180,034 - 91,188,165 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	10	87,652,254 - 87,661,173 (-)	NCBI	Mhudiblu_PPA_v0		panPan3

ANKRD1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	28	5,569,120 - 5,578,393 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	28	5,569,501 - 5,601,956 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	28	5,736,579 - 5,745,849 (-)	NCBI
ROS_Cfam_1.0	28	5,789,401 - 5,799,972 (-)	NCBI
ROS_Cfam_1.0 Ensembl	28	5,789,403 - 5,823,534 (-)	Ensembl
UMICH_Zoey_3.1	28	5,546,460 - 5,555,716 (-)	NCBI
UNSW_CanFamBas_1.0	28	5,585,466 - 5,594,725 (-)	NCBI
UU_Cfam_GSD_1.0	28	5,750,959 - 5,760,237 (-)	NCBI

Ankrd1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	41,870,291 - 41,878,306 (+)	NCBI
SpeTri2.0	NW_004936601	3,502,844 - 3,510,919 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ANKRD1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	102,603,777 - 102,612,839 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	102,603,777 - 102,612,857 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	111,714,967 - 111,724,055 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ANKRD1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	9	84,248,133 - 84,257,276 (-)	NCBI	ChlSab1.1		chlSab2
ChlSab1.1 Ensembl	9	84,247,241 - 84,257,170 (-)	Ensembl	ChlSab1.1		chlSab2
Vero_WHO_p1.0	NW_023666048	44,957,846 - 44,966,995 (-)	NCBI	Vero_WHO_p1.0

Ankrd1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624737	2,127,253 - 2,136,181 (-)	NCBI	HetGla_female_1.0		hetGla2

Position Markers

RH128736

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	233,815,953 - 233,816,154 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	254,727,088 - 254,727,288	NCBI	Rnor6.0
Rnor_5.0	1	262,046,397 - 262,046,597	UniSTS	Rnor5.0
RGSC_v3.4	1	240,316,217 - 240,316,417	UniSTS	RGSC3.4
Celera	1	230,915,054 - 230,915,254	UniSTS
RH 3.4 Map	1	1586.6	UniSTS
Cytogenetic Map	1	q53	UniSTS

RH130311

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	233,815,948 - 233,816,148 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	254,727,083 - 254,727,282	NCBI	Rnor6.0
Rnor_5.0	1	262,046,403 - 262,046,602	UniSTS	Rnor5.0
RGSC_v3.4	1	240,316,212 - 240,316,411	UniSTS	RGSC3.4
Celera	1	230,915,049 - 230,915,248	UniSTS
RH 3.4 Map	4	511.12	UniSTS
Cytogenetic Map	1	q53	UniSTS

RH134094

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	233,825,496 - 233,825,716 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	254,736,633 - 254,736,852	NCBI	Rnor6.0
Rnor_5.0	1	262,036,833 - 262,037,052	UniSTS	Rnor5.0
RGSC_v3.4	1	240,325,889 - 240,326,108	UniSTS	RGSC3.4
Celera	1	230,924,483 - 230,924,702	UniSTS
RH 3.4 Map	1	1584.7	UniSTS
Cytogenetic Map	1	q53	UniSTS

AI556107

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	233,816,132 - 233,816,269 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	254,727,267 - 254,727,403	NCBI	Rnor6.0
Rnor_5.0	1	262,046,282 - 262,046,418	UniSTS	Rnor5.0
RGSC_v3.4	1	240,316,396 - 240,316,532	UniSTS	RGSC3.4
Celera	1	230,915,233 - 230,915,369	UniSTS
RH 3.4 Map	1	1586.91	UniSTS
Cytogenetic Map	1	q53	UniSTS

RH140168

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	233,820,715 - 233,820,928 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	254,731,853 - 254,732,065	NCBI	Rnor6.0
Rnor_5.0	1	262,041,620 - 262,041,832	UniSTS	Rnor5.0
RGSC_v3.4	1	240,321,109 - 240,321,321	UniSTS	RGSC3.4
Celera	1	230,919,703 - 230,919,915	UniSTS
Cytogenetic Map	1	q53	UniSTS

Ankrd1

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	233,820,013 - 233,821,266 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	254,731,151 - 254,732,403	NCBI	Rnor6.0
Rnor_5.0	1	262,041,282 - 262,042,534	UniSTS	Rnor5.0
Celera	1	230,919,001 - 230,920,253	UniSTS
Cytogenetic Map	1	q53	UniSTS

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2292216	Bw80	Body weight QTL 80	3.23	0.0019	body mass (VT:0001259)	body weight (CMO:0000012)	1	213533809	243914901	Rat
70211	Niddm24	Non-insulin dependent diabetes mellitus QTL 24	3.79		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	1	214647894	259647894	Rat
631215	Stl8	Serum triglyceride level QTL 8	9.27	0.0001	blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	1	225126575	260522016	Rat
2302040	Pia35	Pristane induced arthritis QTL 35	3.8	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G1 level (CMO:0002115)	1	216255568	260522016	Rat
2302375	Bw83	Body weight QTL 83	4.87	0.0002	body mass (VT:0001259)	body weight (CMO:0000012)	1	197697768	242697768	Rat
2302378	Insul11	Insulin level QTL 11	3.25		blood insulin amount (VT:0001560)	serum insulin level (CMO:0000358)	1	144267353	251128347	Rat
61455	Niddm7	Non-insulin dependent diabetes mellitus QTL 7	5.5		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	1	214537555	238757011	Rat
724531	Uae5	Urinary albumin excretion QTL 5	4		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	1	150700142	252085212	Rat
724533	Rf51	Renal function QTL 51	5.3	0.0002	kidney plasma flow trait (VT:0005524)	renal plasma flow (CMO:0001914)	1	218753816	256448513	Rat
724538	Kidm1	Kidney mass QTL 1	3.2		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	213707201	252085212	Rat
724552	Glom2	Glomerulus QTL 2	3.3	0.0001	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)	1	222363780	260522016	Rat
734767	Niddm57	Non-insulin dependent diabetes mellitus QTL 57			body mass (VT:0001259)	body weight (CMO:0000012)	1	224054293	260122809	Rat
734768	Niddm59	Non-insulin dependent diabetes mellitus QTL 59			body mass (VT:0001259)	body weight (CMO:0000012)	1	213843987	258843987	Rat
734769	Niddm58	Non-insulin dependent diabetes mellitus QTL 58			body mass (VT:0001259)	body weight (CMO:0000012)	1	224569538	260122809	Rat
1298084	Thym4	Thymus enlargement QTL 4	10.68		thymus mass (VT:0004954)	thymus weight to body weight ratio (CMO:0000612)	1	197814409	242814409	Rat
631658	Cm7	Cardiac mass QTL 7	5.32	0.0001	aorta mass (VT:0002845)	aorta weight (CMO:0000076)	1	196248093	241248093	Rat
631669	Iddm9	Insulin dependent diabetes mellitus QTL 9	2.8	0.039	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	1	233190394	258625266	Rat
1354580	Scort1	Serum corticosterone level QTL 1	3.4		blood corticosterone amount (VT:0005345)	blood corticosterone level (CMO:0001172)	1	156677124	256448636	Rat
1581544	Rf52	Renal function QTL 52		0.05	total urine protein amount (VT:0000032)	urine protein excretion rate to body weight ratio (CMO:0001099)	1	232156370	259647894	Rat
731175	Uae20	Urinary albumin excretion QTL 20	3.5	0.0018	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	221264111	259647894	Rat
738032	Hcas5	Hepatocarcinoma susceptibility QTL 5	3.12		liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	176426412	257976495	Rat
1641926	Teswt2	Testicular weight QTL 2	2.82		testis mass (VT:1000644)	both testes wet weight (CMO:0000175)	1	197697768	238755659	Rat
1598821	Rf55	Renal function QTL 55	6.3		renal blood flow trait (VT:2000006)	ratio of change in renal blood flow to change in renal perfusion pressure (CMO:0001239)	1	218748008	257976495	Rat
2300175	Bmd40	Bone mineral density QTL 40	15.4	0.0001	femur mineral mass (VT:0010011)	bone mineral density (CMO:0001226)	1	201554356	246554356	Rat
2293655	Bss36	Bone structure and strength QTL 36	10.66	0.0001	femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	1	201554356	246554356	Rat
2293674	Bss39	Bone structure and strength QTL 39	7.1	0.0001	femur strength trait (VT:0010010)	femur total energy absorbed before break (CMO:0001677)	1	201554356	246554356	Rat
2293694	Bss38	Bone structure and strength QTL 38	7.05	0.0001	femur strength trait (VT:0010010)	femur stiffness (CMO:0001674)	1	201554356	246554356	Rat
2293700	Bmd27	Bone mineral density QTL 27	6.6	0.0001	femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	1	224054293	243747962	Rat
2293701	Bmd34	Bone mineral density QTL 34	8.3	0.0001	femur strength trait (VT:0010010)	femoral neck ultimate force (CMO:0001703)	1	224054293	243747962	Rat
631843	Bw116	Body weight QTL 116	4.1	0.016	abdominal adipose amount (VT:1000220)	abdominal fat pad weight (CMO:0000088)	1	224054293	260122809	Rat
634313	Niddm43	Non-insulin dependent diabetes mellitus QTL 43			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	199050459	259647894	Rat
634321	Hc1	Hypercalciuria QTL 1	2.91		urine calcium amount (VT:0002985)	urine calcium excretion rate (CMO:0000763)	1	178810256	240830002	Rat
1357335	Bw39	Body weight QTL 39	3.3		body mass (VT:0001259)	body weight (CMO:0000012)	1	197814409	242814409	Rat
1357399	Bw45	Body weight QTL 45	3.05		body mass (VT:0001259)	body mass index (BMI) (CMO:0000105)	1	206329708	251329708	Rat
1357404	Bw42	Body weight QTL 42	4.49	0.0001	body mass (VT:0001259)	body weight (CMO:0000012)	1	206329708	251329708	Rat
1600363	Hc6	Hypercalciuria QTL 6	2.7		urine calcium amount (VT:0002985)	urine calcium excretion rate (CMO:0000763)	1	203995416	244113296	Rat
1600374	Mcs17	Mammary carcinoma susceptibility QTL 17	3		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	1	197670404	242670404	Rat
1600388	Niddm67	Non-insulin dependent diabetes mellitus QTL 67	5.84	0.000004	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	1	195804352	257091168	Rat
1600392	Bw123	Body weight QTL 123		0.001	body mass (VT:0001259)	body weight (CMO:0000012)	1	223201027	260522016	Rat
1600395	Niddm69	Non-insulin dependent diabetes mellitus QTL 69	4.14	0.0002	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	1	195804352	257091168	Rat
1600396	Niddm68	Non-insulin dependent diabetes mellitus QTL 68	4.97	0.0003	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	1	195804352	257091168	Rat
1600397	Edcs4	Endometrial carcinoma susceptibility QTL 4	2.2		uterus morphology trait (VT:0001120)	percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)	1	206081677	251081677	Rat
1578759	Uae30	Urinary albumin excretion QTL 30	3.3	0.003	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	150700247	252085048	Rat
1578763	Kidm29	Kidney mass QTL 29	3.3	0.0001	kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	1	179567751	260522016	Rat
1578778	Pur4	Proteinuria QTL 4	3.3	0.003	total urine protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	1	150700247	252085048	Rat
1300108	Rf8	Renal function QTL 8	3.75		renal blood flow trait (VT:2000006)	absolute change in renal vascular resistance (CMO:0001900)	1	228581588	259647894	Rat
1354610	Bw34	Body weight QTL 34	4.1		body mass (VT:0001259)	body weight (CMO:0000012)	1	151162512	256448636	Rat
1354624	Cm35	Cardiac mass QTL35	5.7		heart left ventricle mass (VT:0007031)	calculated heart weight (CMO:0000073)	1	177227632	256448636	Rat
1354646	Kidm18	Kidney mass QTL 18	5.7		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	151162512	256448636	Rat
1354652	Kidm20	Kidney mass QTL 20	4.3		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	177227632	256448636	Rat
1354661	Bw33	Body weight QTL 33	5.2		body mass (VT:0001259)	body weight (CMO:0000012)	1	151162512	256448636	Rat
1549910	Bw54	Body weight QTL 54		0.05	body mass (VT:0001259)	body weight (CMO:0000012)	1	214647894	259647894	Rat
2316896	Gluco57	Glucose level QTL 57	7.2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	228985440	245907899	Rat
1549837	Hcar15	Hepatocarcinoma resistance QTL 15		0.05	liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	153136852	260522016	Rat
1358191	Ept10	Estrogen-induced pituitary tumorigenesis QTL 10	3.8		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	1	192825253	243914732	Rat
2292220	Bp306	Blood pressure QTL 306	3.47	0.00087	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	164310393	243914901	Rat
1358890	Bp259	Blood pressure QTL 259	3.06		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	210702053	260522016	Rat
1358898	Bp255	Blood pressure QTL 255	3.6		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	191019702	246062233	Rat
1358916	Kidm22	Kidney mass QTL 22	3.32		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	1	210702053	240947965	Rat
1358292	Cm37	Cardiac mass QTL 37	6.2	0.00000081	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	1	196248093	241248093	Rat
61327	Eae7	Experimental allergic encephalomyelitis QTL 7	5.6		body mass (VT:0001259)	change in body weight (CMO:0002045)	1	216255568	260522016	Rat
61376	Bp42	Blood pressure QTL 42	23.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	197814409	242814409	Rat
61400	Niddm1	Non-insulin dependent diabetes mellitus QTL 1	11		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	218753689	245907899	Rat
8655655	Arrd2	Age-related retinal degeneration QTL 2	7.79		retinal layer morphology trait (VT:0003727)	percentage of study population developing retinopathy during a period of time (CMO:0002453)	1	183970203	243914901	Rat
7794788	Mcs32	Mammary carcinoma susceptibility QTL 32	2.61		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	1	115540693	238914717	Rat
7421630	Bp362	Blood pressure QTL 362		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	118608292	241799120	Rat
8552891	Epfw5	Epididymal fat weight QTL 5	4.4		epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	1	193113876	238113876	Rat
7394701	Uae46	Urinary albumin excretion QTL 46	3.6	0.0056	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	201554356	246554356	Rat
8655855	Arrd3	Age-related retinal degeneration QTL 3	3.07		lens clarity trait (VT:0001304)	cataract incidence/prevalence measurement (CMO:0001585)	1	183970203	243914901	Rat
10053715	Scort24	Serum corticosterone level QTL 24	2.13	0.0088	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	1	221414816	260522016	Rat
10059587	Bw173	Body weight QTL 173	3.23	0.025	body mass (VT:0001259)	body weight (CMO:0000012)	1	202069611	247069611	Rat
10059590	Kidm44	Kidney mass QTL 44	3.42	0.025	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	1	191033875	236033875	Rat

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	104
Count of miRNA genes:	85
Interacting mature miRNAs:	99
Transcripts:	ENSRNOT00000025258
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High		19
Medium		25	2		2		2	3				11	2
Low	3		55	41	17	41	6	8	53	35	36		6
Below cutoff									21		5

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_013220	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008760363	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC105469	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC072699	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473953	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000047	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	L81174	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U50736	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000025258 ⟹ ENSRNOP00000025258

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	233,815,853 - 233,824,410 (-)	Ensembl
Rnor_6.0 Ensembl	1	254,726,969 - 254,735,548 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000097402 ⟹ ENSRNOP00000084263

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	233,815,854 - 233,824,597 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000108356 ⟹ ENSRNOP00000083877

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	233,815,851 - 233,824,403 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000108831 ⟹ ENSRNOP00000088225

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	233,815,851 - 233,824,403 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000117221 ⟹ ENSRNOP00000097020

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	233,815,853 - 233,834,919 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000120144 ⟹ ENSRNOP00000097010

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	233,815,857 - 233,824,289 (-)	Ensembl

RefSeq Acc Id:

NM_013220 ⟹ NP_037352

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	233,815,860 - 233,824,412 (-)	NCBI
Rnor_6.0	1	254,726,994 - 254,735,548 (-)	NCBI
Rnor_5.0	1	262,038,137 - 262,046,691 (+)	NCBI
RGSC_v3.4	1	240,316,123 - 240,324,804 (-)	RGD
Celera	1	230,914,960 - 230,923,398 (-)	RGD

Sequence:

show sequence

CCCGGGCAGGTCCAGGGGTTCAGCCACAAGAGGGAAAAACATAGACTAACGGCTGCCAACATGA
TGGTTTTTCGAGTAGAGGAGCTGGTAACGGGCAAAAAGAACAGCAATGGGTCCTCAGGGGAGTT
CCTTCCTGGCGAGTTCAGAAATGGAGAGTATGAAGCTGCTGTTGCCTTGGAGAAACAAGAGGAC
TTGAAGACACTTCCAGCCAACAGTGTGAACCTGGGGGAAGAACAACGGAAAAGTGAGAAAGTTC
GAGAGGCAGAGCTCAAAAAGAAAAAACTAGAACAAAGATCAAAGCTTGAAAACTTAGAAGACCT
TGAAATAATTGTTCAACTGAAGAAAAGAAAAAAATACAAGAAAACTAAAGTTCCAGTTGTGAAG
GAACCGGAGCCTGAAATTATTACTGAACCTGTGGATGTGCCAAGGTTTCTGAAAGCTGCACTGG
AGAACAAACTGCCAGTTGTAGAGAAATTCCTGTCAGACAAGAACAGCCCCGACGTCTGCGATGA
GTATAAACGGACCGCTCTCCATAGAGCATGCTTAGAAGGACACTTGGCGATCGTGGAGAAGTTA
ATGGAGGCTGGAGCCCAGATTGAATTCCGAGATATGCTGGAATCCACAGCCATCCACTGGGCAT
GTCGTGGAGGAAACCTGGATGTCCTGAAACTGTTGCTAAACAAAGGTGCCAAAATCAGTGCCCG
AGACAAGCTGCTCAGCACAGCGCTGCACGTGGCGGTGAGGACCGGTCACTACGAGTGTGCTGAG
CACCTCATCGCCTGCGAGGCGGATCTCAATGCCAAGGACAGAGAAGGAGACACCCCTCTGCATG
ATGCGGTGAGGTTGAATCGCTACAAGATGATCCGGCTCTTGATGACCTTCGGTGCGGACCTCAA
TGTCAAGAACTGTGCTGGGAAGATCCCTATGGATCTGGTGTTGCACTGGCAGAATGGAACCAAA
GCGATATTCGACAGCCTCAAGGAGAATGCCTACAAAAACTCGCGCATAGCTACGTTCTGAGGAA
AGAGACTCGACAGGAGCTGTTCTCAGCCGTTTTCAAAACATTTCCCAGCAGCGGAGCAACCAGC
TATAACACCCAGCTTTTGTTTGCCAGCCAAATAGGGAGATAAGCTTTAAAGACGCTTCATGGAA
GGACCCTGGGTTAGAGATGCTAACATGTCCTCTAGCGATGCTCACCATTTTTATCTGCTCCTAT
TTATTTATTTATTTATTTCATAGCACTGGTAGTCAGGTTTTCATGAGCATCATTTTGGGGGAGC
AAGACTTAATCTGTGTGTAACATTCGGAGTCTTCCCGTGGCTCTAAAACCGCGTGGGTGAATGG
TGTCTAATCTCCCTTTTGTGTCCTCACTTGCATTAAAGCTACTCAAGGTATTTTTGAAAGCCAA
GGGTTGGTCGGTCGCTGCAGCCCTTCTCTGGATTCTCACTGCTGATATCCGAATGAAGCAGCAG
AAGGTGTACAGGAATGCAGAAGGGGATGGGAGCAGTTCTGCAGGACCTAAGCCGTGGCTCGCCA
GGCACCCACAGGTGTGGTTTGCCGGATCACACAGTGCCGAGGTGAAGGCCACGTCAGGAGCGTG
TGTGGAGGGGGATGGAGGGAGTAGGCAATGGGGCCTCACTAACCTGAGGTCGATGAGAGGAAAA
AGTCCAAAAGGACATGCCCTGTAAATGTGTAAATGGTATTGTGTTGTATGCATATTTTATATTC
CTAATAAATGCAAACTAATTC

hide sequence

RefSeq Acc Id:

XM_008760363 ⟹ XP_008758585

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	233,815,851 - 233,834,891 (-)	NCBI
Rnor_6.0	1	254,726,985 - 254,745,673 (-)	NCBI

Sequence:

show sequence

GCAGAGCAACTTCCTCATTCATGGCAGCATCCCCAAACATGGCTTGGAAGGGACGAAGGTGCTG
CAAAAAGCCGAGAGATAAAACTGGTCAGGTGAGAACTATGCCATCAAGCCACAAGCGACATGCT
CAGCCTGGAGTAACGGGCAAAAAGAACAGCAATGGGTCCTCAGGGGAGTTCCTTCCTGGCGAGT
TCAGAAATGGAGAGTATGAAGCTGCTGTTGCCTTGGAGAAACAAGAGGACTTGAAGACACTTCC
AGCCAACAGTGTGAACCTGGGGGAAGAACAACGGAAAAGTGAGAAAGTTCGAGAGGCAGAGCTC
AAAAAGAAAAAACTAGAACAAAGATCAAAGCTTGAAAACTTAGAAGACCTTGAAATAATTGTTC
AACTGAAGAAAAGAAAAAAATACAAGAAAACTAAAGTTCCAGTTGTGAAGGAACCGGAGCCTGA
AATTATTACTGAACCTGTGGATGTGCCAAGGTTTCTGAAAGCTGCACTGGAGAACAAACTGCCA
GTTGTAGAGAAATTCCTGTCAGACAAGAACAGCCCCGACGTCTGCGATGAGTATAAACGGACCG
CTCTCCATAGAGCATGCTTAGAAGGACACTTGGCGATCGTGGAGAAGTTAATGGAGGCTGGAGC
CCAGATTGAATTCCGAGATATGCTGGAATCCACAGCCATCCACTGGGCATGTCGTGGAGGAAAC
CTGGATGTCCTGAAACTGTTGCTAAACAAAGGTGCCAAAATCAGTGCCCGAGACAAGCTGCTCA
GCACAGCGCTGCACGTGGCGGTGAGGACCGGTCACTACGAGTGTGCTGAGCACCTCATCGCCTG
CGAGGCGGATCTCAATGCCAAGGACAGAGAAGGAGACACCCCTCTGCATGATGCGGTGAGGTTG
AATCGCTACAAGATGATCCGGCTCTTGATGACCTTCGGTGCGGACCTCAATGTCAAGAACTGTG
CTGGGAAGACCCCTATGGATCTGGTGTTGCACTGGCAGAATGGAACCAAAGCGATATTCGACAG
CCTCAAGGAGAATGCCTACAAAAACTCGCGCATAGCTACGTTCTGAGGAAAGAGACTCGACAGG
AGCTGTTCTCAGCCGTTTTCAAAACATTTCCCAGCAGCAGAGCAACCAGCTATAACACCCAGCT
TTTGTTTGCCAGCCAAATAGGGAGATAAGCTTTAAAGACGCTTCATGGAAGCCCTGGGTTAGAG
ATGTTAACATGTCCTCTAGCGATGCTCACCATTTTTATCTGCTCCTATTTATTTATTTATTTAT
TTCATAGCACTGGTAGTCAGGTTTTCATGAGCATCATTTTGGGGGAGCAAGACTTAATCTGTGT
GTAACATTCGGAGTCTTCCCGTGGCTCTAAAACCGCGTGGGTGAATGGTGTCTAATCGCACCCT
TTTGTGTCCTCACTTGCATTAAAGCTACTCAAGGTATTTTTGAAAGGCAAGGGTTGGTCGGTCG
CCGCAGCCCTTCTCTGGATTCTCACTGCTGATATCCGAATGAAGCAGCAGAAGGTGTACAGGAA
TGCAGAAGGGGATGGGAGCAGTTCTGCAGGACCTAAGCCGTGGCTCGCCAGGCACCCACAGGTG
TGGTTTGCCGGATCACACAGTGCCGAGGTGAAGGCCACGTCAGGAGCGTGTGTGGAGGGGGATG
GAGGGAGTAGGCAATGGGGCCTCACTAACCTGAGGTCGATGAGAGGAAAAGTCAAAAGGACATG
CCCTGTAAATGTGTAAATGTGTATTGTGTTGTACGCATATTTTATATTCCTAATAAATGCAAAC
TAATTCTCTGCCGTA

hide sequence

Protein Sequences


Protein RefSeqs	NP_037352	(Get FASTA)	NCBI Sequence Viewer
	XP_008758585	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAD10401	(Get FASTA)	NCBI Sequence Viewer
	AAH72699	(Get FASTA)	NCBI Sequence Viewer
	AAL77519	(Get FASTA)	NCBI Sequence Viewer
	EDM13180	(Get FASTA)	NCBI Sequence Viewer
	EDM13181	(Get FASTA)	NCBI Sequence Viewer
	Q8R560	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_037352 ⟸ NM_013220

- Sequence:

show sequence

MMVFRVEELVTGKKNSNGSSGEFLPGEFRNGEYEAAVALEKQEDLKTLPANSVNLGEEQRKSEK
VREAELKKKKLEQRSKLENLEDLEIIVQLKKRKKYKKTKVPVVKEPEPEIITEPVDVPRFLKAA
LENKLPVVEKFLSDKNSPDVCDEYKRTALHRACLEGHLAIVEKLMEAGAQIEFRDMLESTAIHW
ACRGGNLDVLKLLLNKGAKISARDKLLSTALHVAVRTGHYECAEHLIACEADLNAKDREGDTPL
HDAVRLNRYKMIRLLMTFGADLNVKNCAGKIPMDLVLHWQNGTKAIFDSLKENAYKNSRIATF

hide sequence

RefSeq Acc Id:

XP_008758585 ⟸ XM_008760363

- Peptide Label:

isoform X1

- Sequence:

show sequence

MAASPNMAWKGRRCCKKPRDKTGQVRTMPSSHKRHAQPGVTGKKNSNGSSGEFLPGEFRNGEYE
AAVALEKQEDLKTLPANSVNLGEEQRKSEKVREAELKKKKLEQRSKLENLEDLEIIVQLKKRKK
YKKTKVPVVKEPEPEIITEPVDVPRFLKAALENKLPVVEKFLSDKNSPDVCDEYKRTALHRACL
EGHLAIVEKLMEAGAQIEFRDMLESTAIHWACRGGNLDVLKLLLNKGAKISARDKLLSTALHVA
VRTGHYECAEHLIACEADLNAKDREGDTPLHDAVRLNRYKMIRLLMTFGADLNVKNCAGKTPMD
LVLHWQNGTKAIFDSLKENAYKNSRIATF

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RefSeq Acc Id:

ENSRNOP00000025258 ⟸ ENSRNOT00000025258

RefSeq Acc Id:

ENSRNOP00000097010 ⟸ ENSRNOT00000120144

RefSeq Acc Id:

ENSRNOP00000088225 ⟸ ENSRNOT00000108831

RefSeq Acc Id:

ENSRNOP00000097020 ⟸ ENSRNOT00000117221

RefSeq Acc Id:

ENSRNOP00000083877 ⟸ ENSRNOT00000108356

RefSeq Acc Id:

ENSRNOP00000084263 ⟸ ENSRNOT00000097402

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13690871

Promoter ID:

EPDNEW_R1396

Type:

single initiation site

Name:

Ankrd1_1

Description:

ankyrin repeat domain 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	1	254,735,550 - 254,735,610	EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)

ACI/EurMcwi (2019)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

ACI/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

ACI/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

ACI/N (2020)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

ACI/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

BBDP/Wor (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

BN-Lx/CubMcwi (2019)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BN/NHsdMcwi (2019)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BN/NHsdMcwi (2020)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BN/SsN (2020)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BN/SsN (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

BUF/N (2020)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BXH2/CubMcwi (2020)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BXH3/CubMcwi (2020)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

Buf/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

COP/CrCrl (MCW & UW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob) University of Wisconsin (Dr. James Shull)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Charles River Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)

DA/OlaHsd (2019)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Envigo
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

F344/DuCrl (2019)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

F344/N (2020)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

F344/NCrl (2019)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

F344/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

F344/NRrrc (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

F344/Stm (2019)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

FHH/EurMcwi (2019)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

FHH/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHH/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

FHL/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHL/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

FXLE16/Stm (2020)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

FXLE18/Stm (2020)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

GH/OmrMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

GK/FarMcwi (2019)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

GK/Ox (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

HXB10/IpcvMcwi (2019)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

HXB2/IpcvMcwi (2019)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

HXB20/IpcvMcwi (2020)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

HXB31/IpcvMcwi (2019)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

HXB4/IpcvMcwi (2020)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LE/Stm (2019)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LE/Stm (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/Crl (2019)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEW/Crl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/NCrlBR (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEXF10A/StmMcwi (2020)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF11/Stm (2020)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF1A/Stm (2019)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF1C/Stm (2019)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF2B/Stm (2019)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF3/Stm (2020)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF4/Stm (2020)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LH/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LH/MavRrrcAek (2020)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Kwitek
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LL/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LL/MavRrrcAek (2020)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Kwitek
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LN/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LN/MavRrrcAek (2020)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Kwitek
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

M520/N (2020)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

M520/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

M520/NRrrcMcwi (2019)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

MHS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MNS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MR/N (2020)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

MR/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

MWF/Hsd (2019)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

PVG/Seac (2019)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

SBH/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBH/Ygl sequenced by MCW

SBH/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SBN/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBN/Ygl sequenced by MCW

SBN/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHR/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHR/OlalpcvMcwi (2019)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

SHRSP/A3NCrl (2019)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

SHRSP/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SR/JrHsd (2020)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Envigo
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

SR/JrHsd (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Harlan Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SR/JrHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/Jr (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/JrHsdMcwi (2019)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

SS/JrHsdMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SS/JrHsdMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WAG/Rij (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WAG/RijCrl (2020)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

WKY/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/N (2020)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

WKY/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

WKY/NCrl (2019)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

WKY/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WN/N (2020)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

WN/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Damaging Variants

Assembly: Rnor_6.0

Chromosome	Start Pos	End Pos	Reference Nucleotide	Variant Nucleotide	Variant Type	Strain
1	254735067	254735068	T	A	snv	GK/Ox (RGD), SHR/NHsd (RGD), BXH2/CubMcwi (2020), SHR/OlalpcvMcwi (2019), HXB20/IpcvMcwi (2020), HXB2/IpcvMcwi (2019), HXB4/IpcvMcwi (2020), GK/FarMcwi (2019)

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:61989	AgrOrtholog
Ensembl Genes	ENSRNOG00000018598	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein	ENSRNOP00000025258	UniProtKB/Swiss-Prot
	ENSRNOP00000083877	ENTREZGENE
	ENSRNOP00000097020	ENTREZGENE
Ensembl Transcript	ENSRNOT00000025258	UniProtKB/Swiss-Prot
	ENSRNOT00000108356	ENTREZGENE
	ENSRNOT00000117221	ENTREZGENE
Gene3D-CATH	1.25.40.20	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7105899	IMAGE-MGC_LOAD
InterPro	Ankyrin_rpt	UniProtKB/Swiss-Prot
	Ankyrin_rpt-contain_dom	UniProtKB/Swiss-Prot
	Ankyrin_rpt-contain_sf	UniProtKB/Swiss-Prot
KEGG Report	rno:27064	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:91764	IMAGE-MGC_LOAD
NCBI Gene	27064	ENTREZGENE
Pfam	Ank	UniProtKB/Swiss-Prot
	Ank_2	UniProtKB/Swiss-Prot
PhenoGen	Ankrd1	PhenoGen
PRINTS	ANKYRIN	UniProtKB/Swiss-Prot
PROSITE	ANK_REP_REGION	UniProtKB/Swiss-Prot
	ANK_REPEAT	UniProtKB/Swiss-Prot
SMART	ANK	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF48403	UniProtKB/Swiss-Prot
TIGR	TC204620
UniProt	ANKR1_RAT	UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary	Q9Z1F0	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-03-09	Ankrd1	ankyrin repeat domain 1	LOC102552909	uncharacterized LOC102552909	Data Merged	737654	PROVISIONAL
2013-12-18	LOC102552909	uncharacterized LOC102552909			Symbol and Name status set to provisional	70820	PROVISIONAL
2004-02-05	Ankrd1	ankyrin repeat domain 1 (cardiac muscle)	Alrp	ankyrin-like repeat protein	Symbol and name updated to reflect Human and Mouse nomenclature	625702	APPROVED
2002-06-10	Alrp	ankyrin-like repeat protein			Name updated	70584	APPROVED

RGD Curation Notes

Note Type	Note	Reference
gene_cellular_localization	localized to the nucleus	634545
gene_drugs	expression is inhibited by the antineoplastic drug doxorubicin	634545
gene_expression	expressed in cardiomyocytes	634545

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar

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