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Gene: Gucy1b2 (guanylate cyclase 1 soluble subunit beta 2) Rattus norvegicus
Symbol: Gucy1b2
Name: guanylate cyclase 1 soluble subunit beta 2
Description: Exhibits ion binding activity. Predicted to be involved in cGMP-mediated signaling. Predicted to localize to the cytosol. Orthologous to human GUCY1B2 (guanylate cyclase 1 soluble subunit beta 2 (pseudogene)); PARTICIPATES IN long term depression; purine metabolic pathway; INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: GCS-beta-2; guanylate cyclase 1 soluble beta 2; guanylate cyclase 1, soluble, beta 2; Guanylate cyclase soluble beta 2 (GTP pyrophosphate - lyase); guanylate cyclase soluble subunit beta-2; guanylate cyclase, soluble, beta 2; Guanylate cyclase, soluble, beta 2 (GTP pyrophosphate - lyase); Gucy1b2a; Gucy1b2b; SGC; soluble guanylate cyclase beta 2a; soluble guanylate cyclase beta 2b
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01545,479,662 - 45,550,285 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1545,479,658 - 45,550,285 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01549,255,071 - 49,325,713 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41541,620,373 - 41,668,802 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11541,636,072 - 41,684,502 (-)NCBI
Celera1536,296,636 - 36,358,650 (-)NCBICelera
Cytogenetic Map15p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Gucy1b2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2770
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.