Slc2a2 (solute carrier family 2 member 2) - Rat Genome Database

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Gene: Slc2a2 (solute carrier family 2 member 2) Rattus norvegicus
Analyze
Symbol: Slc2a2
Name: solute carrier family 2 member 2
RGD ID: 3705
Description: Exhibits D-glucose transmembrane transporter activity; dehydroascorbic acid transmembrane transporter activity; and insulin receptor binding activity. Involved in several processes, including carbohydrate utilization; dehydroascorbic acid transport; and hexose transmembrane transport. Localizes to several cellular components, including apical plasma membrane; basolateral plasma membrane; and brush border membrane. Human ortholog(s) of this gene implicated in Fanconi syndrome; glycogen storage disease; and type 2 diabetes mellitus. Orthologous to human SLC2A2 (solute carrier family 2 member 2); PARTICIPATES IN facilitative sugar transporter mediated glucose transport pathway; Fanconi syndrome pathway; forkhead class A signaling pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: glucose transporter type 2, liver; GLUT-2; Glut2; GTT2; solute carrier family 2 (facilitated glucose transporter), member 2; Solute carrier family 2 A2 (gkucose transporter type 2); Solute carrier family 2 A2 (gkucose transporter, type 2); solute carrier family 2, facilitated glucose transporter member 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Is Marker For: Strains:   SDJ/Hok  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22111,609,798 - 111,639,930 (+)NCBI
Rnor_6.0 Ensembl2114,413,410 - 114,445,395 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.02114,413,427 - 114,445,418 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02134,112,829 - 134,144,459 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42116,036,501 - 116,065,834 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12115,981,388 - 116,010,832 (+)NCBI
Celera2106,800,647 - 106,828,175 (+)NCBICelera
Cytogenetic Map2q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-amino-2-deoxy-D-glucopyranose  (EXP)
2-deoxy-D-glucose  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP,ISO)
3,7-dihydropurine-6-thione  (EXP)
3-chloropropane-1,2-diol  (EXP)
3-O-methyl-D-glucose  (EXP,ISO)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-sulfonyldiphenol  (ISO)
5-fluorouracil  (ISO)
5-iodotubercidin  (ISO)
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide  (ISO)
9-cis-retinoic acid  (EXP,ISO)
acrylamide  (ISO)
actinomycin D  (EXP)
aflatoxin B1  (ISO)
aldehydo-D-glucosamine  (EXP)
aldehydo-D-glucose  (EXP,ISO)
alloxan  (EXP,ISO)
allyl isothiocyanate  (EXP)
alpha-D-galactose  (ISO)
ammonium chloride  (EXP)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atorvastatin calcium  (EXP,ISO)
atrazine  (ISO)
azathioprine  (ISO)
benzo[a]pyrene  (ISO)
beta-D-glucosamine  (EXP)
beta-maltose  (ISO)
bexarotene  (EXP)
bezafibrate  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
boric acid  (ISO)
buta-1,3-diene  (ISO)
cadmium atom  (EXP)
cadmium dichloride  (EXP,ISO)
calcitriol  (ISO)
calcium atom  (EXP)
calcium(0)  (EXP)
carbon nanotube  (ISO)
chlordecone  (ISO)
cholesterol  (ISO)
choline  (ISO)
chromium(6+)  (EXP,ISO)
ciguatoxin CTX1B  (ISO)
cis-caffeic acid  (ISO)
cisplatin  (EXP)
cobalt dichloride  (EXP)
copper(II) sulfate  (ISO)
curcumin  (EXP,ISO)
cyclophosphamide  (ISO)
cyclosporin A  (ISO)
cypermethrin  (ISO)
cytochalasin B  (EXP,ISO)
D-glucose  (EXP,ISO)
D-mannopyranose  (EXP)
decabromodiphenyl ether  (EXP)
dehydroascorbic acid  (ISO)
dexamethasone  (EXP)
diarsenic trioxide  (ISO)
diazoxide  (EXP)
dibutyl phthalate  (ISO)
diclofenac  (ISO)
dicrotophos  (ISO)
dieldrin  (EXP)
diethyl maleate  (EXP)
diethylstilbestrol  (EXP)
dioxygen  (EXP)
disodium selenite  (ISO)
ebselen  (EXP,ISO)
endosulfan  (EXP,ISO)
ethanol  (EXP,ISO)
flavonoids  (EXP)
folic acid  (ISO)
formaldehyde  (EXP)
fructose  (EXP,ISO)
furan  (EXP)
galactose  (ISO)
genistein  (EXP)
gentamycin  (EXP)
glafenine  (EXP)
glucose  (EXP,ISO)
glycerol  (EXP)
heptachlor  (EXP)
hesperidin  (ISO)
hexadecanoic acid  (ISO)
hydrogen peroxide  (ISO)
imidacloprid  (EXP)
indometacin  (EXP,ISO)
isoflavones  (EXP)
ketamine  (EXP)
L-dehydroascorbic acid  (ISO)
L-methionine  (ISO)
lipopolysaccharide  (ISO)
maltose  (ISO)
mercaptopurine  (EXP)
mercury dichloride  (EXP)
metacetamol  (ISO)
metformin  (ISO)
methapyrilene  (EXP)
methotrexate  (ISO)
methoxychlor  (EXP)
methylglyoxal  (ISO)
methylmercury chloride  (ISO)
microcystin-LR  (ISO)
mirex  (EXP)
ML-7  (EXP)
monosodium L-glutamate  (ISO)
myricetin  (EXP)
myrtenal  (EXP)
N-acetyl-L-cysteine  (ISO)
N-nitrosodiethylamine  (ISO)
N-nitrosomorpholine  (EXP)
naringin  (ISO)
nefazodone  (EXP)
nickel dichloride  (EXP)
nimesulide  (EXP)
Nonylphenol  (EXP)
O-methyleugenol  (ISO)
ochratoxin A  (EXP)
oleic acid  (ISO)
oxycodone  (EXP)
paracetamol  (ISO)
penconazole  (ISO)
perfluorononanoic acid  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP,ISO)
phenobarbital  (EXP)
phloretin  (EXP,ISO)
phlorizin  (ISO)
pirinixic acid  (EXP,ISO)
potassium dichromate  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP,ISO)
promethazine  (EXP)
propiconazole  (ISO)
purine-6-thiol  (EXP)
quercetin  (ISO)
quercetin 3-O-beta-D-galactopyranoside  (ISO)
rebaudioside A  (ISO)
resveratrol  (EXP,ISO)
rifampicin  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
steviol  (ISO)
stevioside  (ISO)
streptozocin  (EXP,ISO)
styrene  (EXP)
sucrose  (EXP,ISO)
taurine  (EXP,ISO)
Tesaglitazar  (EXP)
tetrachloromethane  (ISO)
tetracycline  (ISO)
thioacetamide  (EXP)
trans-caffeic acid  (ISO)
trichloroethene  (EXP)
Triptolide  (ISO)
troglitazone  (EXP)
urethane  (ISO)
ursodeoxycholic acid  (EXP)
valdecoxib  (EXP)
valproic acid  (ISO)
zearalenone  (ISO)
zinc atom  (EXP)
zinc(0)  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References

References - curated
1. Abasolo I, etal., Eur J Nucl Med Mol Imaging. 2009 Jul;36(7):1156-66. Epub 2009 Feb 28.
2. Ahn YH, etal., Arch Biochem Biophys 1995 Nov 10;323(2):387-96.
3. Angulo C, etal., J Cell Physiol. 2008 Dec;217(3):708-16. doi: 10.1002/jcp.21545.
4. Au A, etal., Biochem J 2002 Oct 1;367(Pt 1):247-54.
5. Eisenberg ML, etal., Cell Physiol Biochem. 2005;15(1-4):51-8.
6. Freitas HS, etal., Mol Cell Endocrinol. 2009 Jun 16;305(1-2):63-70. Epub 2009 Mar 4.
7. GOA data from the GO Consortium
8. Kilpelainen TO, etal., Physiol Genomics. 2007 Oct 22;31(2):264-72. Epub 2007 Jul 17.
9. Lachaal M, etal., Biochim Biophys Acta. 2000 Jun 1;1466(1-2):379-89.
10. Lane RH, etal., Am J Physiol Regul Integr Comp Physiol 2002 Dec;283(6):R1450-60.
11. Lane RH, etal., Am J Physiol. 1999 Jan;276(1 Pt 1):E135-42.
12. Li R, etal., Diabetologia. 2007 Mar;50(3):682-9. Epub 2007 Jan 18.
13. MGD data from the GO Consortium
14. Miyamoto K, etal., FEBS Lett. 1992 Dec 21;314(3):466-70.
15. Morgan EL, etal., J Physiol. 2007 Apr 15;580(Pt. 2):593-604. Epub 2007 Feb 1.
16. Mueckler M, etal., J Biol Chem. 1994 Jul 8;269(27):17765-7.
17. NCBI rat LocusLink and RefSeq merged data July 26, 2002
18. Ngarmukos C, etal., Brain Res. 2001 May 4;900(1):1-8. doi: 10.1016/s0006-8993(01)02184-9.
19. Nolan CJ and Prentki M, Trends Endocrinol Metab. 2008 Oct;19(8):285-91. Epub 2008 Sep 6.
20. OMIM Disease Annotation Pipeline
21. Pipeline to import KEGG annotations from KEGG into RGD
22. Pipeline to import Pathway Interaction Database annotations from NCI into RGD
23. Pipeline to import SMPDB annotations from SMPDB into RGD
24. RGD automated data pipeline
25. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
26. RGD automated import pipeline for gene-chemical interactions
27. Santer R, etal., Nat Genet. 1997 Nov;17(3):324-6.
28. Scheepers A, etal., JPEN J Parenter Enteral Nutr. 2004 Sep-Oct;28(5):364-71.
29. Seino Y, etal., J Clin Endocrinol Metab. 1993 Jan;76(1):75-8.
30. Song J, etal., J Biol Chem 2002 May 3;277(18):15252-60.
31. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
32. Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
33. Thorens B, etal., Cell. 1988 Oct 21;55(2):281-90.
34. Tomita T Endocr Pathol. 1999 Autumn;10(3):213-221.
35. Villanueva-Penacarrillo ML, etal., Endocrine 2001 Jul;15(2):241-8.
Additional References at PubMed
PMID:7589840   PMID:7593639   PMID:8457197   PMID:9751501   PMID:11287626   PMID:12436338   PMID:12526103   PMID:12766174   PMID:12787936   PMID:12921743   PMID:12963802   PMID:14702043  
PMID:14736883   PMID:15297580   PMID:15601832   PMID:15855808   PMID:16627065   PMID:16978589   PMID:17053095   PMID:17148757   PMID:17272349   PMID:17495045   PMID:17673438   PMID:17694297  
PMID:17712721   PMID:17928203   PMID:18154936   PMID:18290345   PMID:18511518   PMID:18708286   PMID:19541015   PMID:19841136   PMID:19883765   PMID:19956534   PMID:20633633   PMID:21621509  
PMID:22068967   PMID:22110271   PMID:23396969   PMID:23746671   PMID:24062089   PMID:24157454   PMID:25687571   PMID:25711084   PMID:25898949   PMID:25956617   PMID:26449613   PMID:26871756  
PMID:27662473   PMID:28011946   PMID:28083649   PMID:28470423   PMID:29178321   PMID:29386586   PMID:31767340  


Genomics

Comparative Map Data
Slc2a2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22111,609,798 - 111,639,930 (+)NCBI
Rnor_6.0 Ensembl2114,413,410 - 114,445,395 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.02114,413,427 - 114,445,418 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02134,112,829 - 134,144,459 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42116,036,501 - 116,065,834 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12115,981,388 - 116,010,832 (+)NCBI
Celera2106,800,647 - 106,828,175 (+)NCBICelera
Cytogenetic Map2q24NCBI
SLC2A2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl3170,996,347 - 171,026,743 (-)EnsemblGRCh38hg38GRCh38
GRCh383170,996,341 - 171,026,721 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh373170,714,136 - 170,744,509 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363172,196,831 - 172,227,462 (-)NCBINCBI36hg18NCBI36
Build 343172,196,838 - 172,227,470NCBI
Celera3169,114,036 - 169,144,639 (-)NCBI
Cytogenetic Map3q26.2NCBI
HuRef3168,084,022 - 168,114,636 (-)NCBIHuRef
CHM1_13170,677,320 - 170,707,971 (-)NCBICHM1_1
Slc2a2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39328,752,052 - 28,782,510 (+)NCBIGRCm39mm39
GRCm39 Ensembl328,752,052 - 28,785,508 (+)Ensembl
GRCm38328,697,903 - 28,728,361 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl328,697,903 - 28,731,359 (+)EnsemblGRCm38mm10GRCm38
MGSCv37328,596,825 - 28,627,283 (+)NCBIGRCm37mm9NCBIm37
MGSCv36328,889,050 - 28,919,403 (+)NCBImm8
Celera328,651,848 - 28,682,069 (+)NCBICelera
Cytogenetic Map3A3NCBI
cM Map312.19NCBI
Slc2a2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554201,101,769 - 1,129,715 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554201,101,769 - 1,129,672 (-)NCBIChiLan1.0ChiLan1.0
SLC2A2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.13176,188,184 - 176,218,722 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3176,188,184 - 176,218,722 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v03168,002,609 - 168,033,237 (-)NCBIMhudiblu_PPA_v0panPan3
SLC2A2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13435,368,583 - 35,398,197 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3435,370,192 - 35,400,409 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3444,378,744 - 44,410,779 (-)NCBI
ROS_Cfam_1.03435,449,090 - 35,481,171 (-)NCBI
UMICH_Zoey_3.13435,390,307 - 35,422,083 (-)NCBI
UNSW_CanFamBas_1.03435,359,864 - 35,391,881 (-)NCBI
UU_Cfam_GSD_1.03435,623,885 - 35,655,904 (-)NCBI
Slc2a2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602102,013,626 - 102,049,304 (-)NCBI
SpeTri2.0NW_0049365931,572,661 - 1,605,071 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC2A2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13109,587,256 - 109,623,787 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113109,592,595 - 109,614,105 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213118,535,745 - 118,557,254 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SLC2A2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11518,434,370 - 18,466,331 (+)NCBI
ChlSab1.1 Ensembl1518,434,916 - 18,467,352 (+)Ensembl
Vero_WHO_p1.0NW_02366606327,204,593 - 27,235,096 (+)NCBI
Slc2a2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473049,026,603 - 49,056,363 (-)NCBI

Position Markers
D2Wox47  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.02114,418,676 - 114,419,081NCBIRnor6.0
RGSC_v3.42116,035,062 - 116,035,472UniSTSRGSC3.4
Celera2106,799,209 - 106,799,618UniSTS
Cytogenetic Map2q24UniSTS
RH127898  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22111,639,700 - 111,639,895 (+)MAPPER
Rnor_6.02114,445,184 - 114,445,378NCBIRnor6.0
Rnor_5.02134,144,225 - 134,144,419UniSTSRnor5.0
RGSC_v3.42116,065,638 - 116,065,832UniSTSRGSC3.4
Celera2106,827,979 - 106,828,173UniSTS
RH 3.4 Map2702.8UniSTS
Cytogenetic Map2q24UniSTS
RH94776  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22111,639,437 - 111,639,721 (+)MAPPER
Rnor_6.02114,444,921 - 114,445,204NCBIRnor6.0
Rnor_5.02134,143,962 - 134,144,245UniSTSRnor5.0
RGSC_v3.42116,065,375 - 116,065,658UniSTSRGSC3.4
Celera2106,827,716 - 106,827,999UniSTS
Cytogenetic Map2q24UniSTS
RH94421  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22111,639,754 - 111,639,919 (+)MAPPER
Rnor_6.02114,445,238 - 114,445,402NCBIRnor6.0
Rnor_5.02134,144,279 - 134,144,443UniSTSRnor5.0
RGSC_v3.42116,065,692 - 116,065,856UniSTSRGSC3.4
Celera2106,828,033 - 106,828,197UniSTS
Cytogenetic Map2q24UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10755499Bp389Blood pressure QTL 3892.61arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)216679272245624402Rat
1302794Stl27Serum triglyceride level QTL 274.40.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)223837491149614623Rat
1358894Kidm24Kidney mass QTL 244.03kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)223837491169852800Rat
1358899Kidm23Kidney mass QTL 233.88kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)223837491169852800Rat
1358901Cm38Cardiac mass QTL 382heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)223837491169852800Rat
1358904Cm39Cardiac mass QTL 392.26heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)223837491169852800Rat
1358910Kidm27Kidney mass QTL 275.77kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)223837491169852800Rat
1358911Kidm28Kidney mass QTL 285.42kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)223837491169852800Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)223837491218957222Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)223837491218957222Rat
1358887Bw50Body weight QTL 502.39body mass (VT:0001259)body weight (CMO:0000012)223837719169852670Rat
1358908Bw49Body weight QTL 493.36body mass (VT:0001259)body weight (CMO:0000012)223837719169852670Rat
1354603Bp243Blood pressure QTL 2433.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)226186097135654963Rat
2290453Scl55Serum cholesterol level QTL 552.83blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)226186097142053534Rat
12879841Cm87Cardiac mass QTL 870.026heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)227161361148295267Rat
12879842Cm88Cardiac mass QTL 880.042heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)227161361148295267Rat
12879843Am3Aortic mass QTL 30.016aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)227161361148295267Rat
12879844Kidm62Kidney mass QTL 620.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227161361148295267Rat
2293835Kiddil5Kidney dilation QTL 53.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)242776916169852800Rat
2293843Kiddil6Kidney dilation QTL 63.1kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)242776916195645082Rat
1298085Bp165Blood pressure QTL 1650.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242776916217498710Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242776916217498710Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)243133606217498545Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)243133606217498545Rat
2293671Bss44Bone structure and strength QTL 4410.970.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)243141290154583160Rat
1354601Slep1Serum leptin concentration QTL 15.39blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)243149788198704485Rat
631266Bp132Blood pressure QTL 1320.0005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)246537589217498710Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)256244671217498710Rat
1558648Smcn1Smooth muscle cell number QTL 10.039blood vessel smooth muscle cell quantity (VT:0010525)aorta smooth muscle cell count per unit vessel length (CMO:0001646)260131410135646395Rat
61438Cia7Collagen induced arthritis QTL 74.60.0001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)260325352147522851Rat
1298080Bp163Blood pressure QTL 1630.02arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266828049217498710Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266828236243550655Rat
1358900Bw48Body weight QTL 484.88body mass (VT:0001259)body weight (CMO:0000012)268865414169852800Rat
1581578Cm49Cardiac mass QTL 494.90.01heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)268866454149614466Rat
7411551Bw131Body weight QTL 13129.60.001body mass (VT:0001259)body weight gain (CMO:0000420)270132175115132175Rat
2317041Aia14Adjuvant induced arthritis QTL 143.29joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)271495404116495404Rat
1354605Rf48Renal function QTL 482.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)275687495221880419Rat
631198Cm22Cardiac mass QTL 224.30.0008heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)278321410158159410Rat
61374Edpm2Estrogen-dependent pituitary mass QTL 24.420.86pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)278321410217498710Rat
2299162Iddm32Insulin dependent diabetes mellitus QTL 322.36blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)280631950149614623Rat
61392Bp6Blood pressure QTL 67arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)282574487127574487Rat
1598865Bp296Blood pressure QTL 2962.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)283656855128656855Rat
8662832Vetf7Vascular elastic tissue fragility QTL 73.5aorta elastin amount (VT:0003905)aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)283754907237610852Rat
1354622Kidm16Kidney mass QTL 163kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)283819608239166203Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)283819608243901375Rat
1578772Stresp14Stress response QTL 1450.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)284424139132130578Rat
2300165Bmd49Bone mineral density QTL 494.80.0001lumbar vertebra mineral mass (VT:0010511)bone mineral density (CMO:0001226)291664872136664872Rat
2300170Bmd45Bone mineral density QTL 4512.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)291664872136664872Rat
2300185Bmd46Bone mineral density QTL 468.40.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)291664872136664872Rat
7207808Bmd89Bone mineral density QTL 894.1femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)291664872136664872Rat
1558653Prcr1Prostate cancer resistance QTL 15prostate integrity trait (VT:0010571)area of ventral prostate occupied by tumorous lesions to total ventral prostate area ratio (CMO:0000899)293995316169852800Rat
1598862Glom9Glomerulus QTL 93.5kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)295946719140946719Rat
1598863Cm65Cardiac mass QTL 652.3heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)295946719140946719Rat
2317886Alcrsp23Alcohol response QTL 232.40.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)296844330141844330Rat
9589093Slep10Serum leptin concentration QTL 103.840.001blood leptin amount (VT:0005667)plasma leptin level (CMO:0000781)2102356980147356980Rat
631566Bp90Blood pressure QTL 900.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2108880910153880910Rat
8662836Vetf8Vascular elastic tissue fragility QTL 80.66thoracic aorta molecular composition trait (VT:0010568)aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)2110965721155965721Rat


Related Rat Strains
The following Strains have been annotated to Slc2a2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:114
Count of miRNA genes:81
Interacting mature miRNAs:98
Transcripts:ENSRNOT00000015866
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 41 41 41 29 1
Low 1 3 1 2 2 6 2 18 2 2
Below cutoff 11 13 15 6 6 50 4 18 7 6

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_012879 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006232207 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039101783 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC078875 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473961 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210842 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218766 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  J03145 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000067 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L28126 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L28127 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L28128 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L28129 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L28130 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L28131 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L28132 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L28133 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L28134 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L28135 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L28678 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000015866   ⟹   ENSRNOP00000015866
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl2114,413,410 - 114,445,395 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000091221   ⟹   ENSRNOP00000071871
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl2114,423,533 - 114,444,520 (+)Ensembl
RefSeq Acc Id: NM_012879   ⟹   NP_037011
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22111,611,848 - 111,639,897 (+)NCBI
Rnor_6.02114,413,586 - 114,445,380 (+)NCBI
Rnor_5.02134,112,829 - 134,144,459 (+)NCBI
RGSC_v3.42116,036,501 - 116,065,834 (+)RGD
Celera2106,800,647 - 106,828,175 (+)RGD
Sequence:
RefSeq Acc Id: XM_006232207   ⟹   XP_006232269
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02114,413,427 - 114,445,418 (+)NCBI
Rnor_5.02134,112,829 - 134,144,459 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039101783   ⟹   XP_038957711
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22111,609,798 - 111,639,930 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_037011   ⟸   NM_012879
- UniProtKB: Q68FZ1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006232269   ⟸   XM_006232207
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000071871   ⟸   ENSRNOT00000091221
RefSeq Acc Id: ENSRNOP00000015866   ⟸   ENSRNOT00000015866
RefSeq Acc Id: XP_038957711   ⟸   XM_039101783
- Peptide Label: isoform X1
Protein Domains
MFS

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691268
Promoter ID:EPDNEW_R1793
Type:multiple initiation site
Name:Slc2a2_1
Description:solute carrier family 2 member 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02114,413,573 - 114,413,633EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3705 AgrOrtholog
Ensembl Genes ENSRNOG00000011875 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000015866 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000071871 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000015866 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000091221 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7127751 IMAGE-MGC_LOAD
InterPro Glc_transpt_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MFS_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MFS_sugar_transport-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MFS_trans_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sugar/inositol_transpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sugar_transporter_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:25351 UniProtKB/TrEMBL
MGC_CLONE MGC:93555 IMAGE-MGC_LOAD
NCBI Gene 25351 ENTREZGENE
Pfam Sugar_tr UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB SLC2A2 RGD
PhenoGen Slc2a2 PhenoGen
PRINTS GLUCTRSPORT2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SUGRTRNSPORT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE MFS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SUGAR_TRANSPORT_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SUGAR_TRANSPORT_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF103473 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC205552
TIGRFAMs TIGR00879 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2K1J9_RAT UniProtKB/TrEMBL
  GTR2_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q68FZ1 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary Q6LE98 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-24 Slc2a2  solute carrier family 2 member 2  Slc2a2  solute carrier family 2 (facilitated glucose transporter), member 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Slc2a2  solute carrier family 2 (facilitated glucose transporter), member 2    solute carrier family 2, member 2  Name updated 1299863 APPROVED
2003-04-09 Slc2a2  solute carrier family 2, member 2    Solute carrier family 2 A2 (gkucose transporter, type 2)  Name updated 629478 APPROVED
2002-06-10 Slc2a2  Solute carrier family 2 A2 (gkucose transporter, type 2)      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_cellular_localization protein localized to jejunal brush border membranes 625552
gene_cellular_localization localized to apical plasma membrane and basolateral membrane 625552
gene_expression expressed in jejunal brush-border membrane 625552
gene_function functions as a transporter of glucose, galactose and fructose 625552
gene_process has low substrate affinity and Km value in the range of 16-20 mM 625552
gene_process involved in hexose transport into enterocytes 625552
gene_process may play a role in hexose transport across intestinal brush border membranes  
gene_regulation regulated by vascular GLP-2 and/or luminal glucose 625552
gene_regulation glucose transporter activity is inhibited by the flavonol quercetin 730195