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Gene: Hck (HCK proto-oncogene, Src family tyrosine kinase) Rattus norvegicus
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Symbol: Hck
Name: HCK proto-oncogene, Src family tyrosine kinase
Description: Predicted to have non-membrane spanning protein tyrosine kinase activity; phosphotyrosine residue binding activity; and signaling receptor binding activity. Predicted to be involved in several processes, including defense response to Gram-positive bacterium; peptidyl-tyrosine autophosphorylation; and regulation of organelle organization. Predicted to colocalize with the actin filament. Orthologous to human HCK (HCK proto-oncogene, Src family tyrosine kinase); PARTICIPATES IN eicosanoid signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; glypican signaling pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-di-tert-butyl-4-methylphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: HCTK; hematopoietic cell kinase; hemopoietic cell kinase; hemopoietic cell tyrosine kinase; p56-HCK; p56Hck; p59Hck; tyrosine-protein kinase HCK
Orthologs:
Homo sapiens (human) : HCK (HCK proto-oncogene, Src family tyrosine kinase)  HGNC  Alliance
Mus musculus (house mouse) : Hck (hemopoietic cell kinase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hck (HCK proto-oncogene, Src family tyrosine kinase)
Pan paniscus (bonobo/pygmy chimpanzee) : HCK (HCK proto-oncogene, Src family tyrosine kinase)
Canis lupus familiaris (dog) : HCK (HCK proto-oncogene, Src family tyrosine kinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hck (HCK proto-oncogene, Src family tyrosine kinase)
Sus scrofa (pig) : HCK (HCK proto-oncogene, Src family tyrosine kinase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.03148,579,917 - 148,623,026 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3148,579,920 - 148,623,033 (+)Ensembl
Rnor_5.03154,982,909 - 155,025,529 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43143,447,697 - 143,490,281 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13143,353,318 - 143,395,900 (+)NCBI
Celera3140,318,662 - 140,361,702 (+)NCBICelera
Cytogenetic Map3q41NCBI
RH 3.4 Map31263.9RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Hck
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2785
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.