STARD4 (StAR related lipid transfer domain containing 4) - Rat Genome Database
Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: STARD4 (StAR related lipid transfer domain containing 4) Homo sapiens
Analyze
Symbol: STARD4
Name: StAR related lipid transfer domain containing 4
RGD ID: 1319833
HGNC Page HGNC
Description: Exhibits cholesterol binding activity and cholesterol transfer activity. Involved in cholesterol transport and positive regulation of steroid metabolic process. Localizes to cytoplasmic vesicle.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: StAR-related lipid transfer (START) domain containing 4; StAR-related lipid transfer domain containing 4; stAR-related lipid transfer protein 4; START domain containing 4 sterol-regulated; START domain containing 4, sterol regulated; START domain-containing protein 4
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl5111,496,033 - 111,512,590 (-)EnsemblGRCh38hg38GRCh38
GRCh385111,491,422 - 111,512,567 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh375110,831,731 - 110,848,233 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365110,861,921 - 110,876,056 (-)NCBINCBI36hg18NCBI36
Build 345110,861,920 - 110,876,056NCBI
Celera5106,779,623 - 106,793,758 (-)NCBI
Cytogenetic Map5q22.1NCBI
HuRef5106,012,693 - 106,026,827 (-)NCBIHuRef
CHM1_15110,265,025 - 110,281,589 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1-benzylpiperazine  (ISO)
17beta-estradiol  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dinitrotoluene  (ISO)
2-hydroxypropanoic acid  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (EXP)
6-propyl-2-thiouracil  (ISO)
acetamide  (ISO)
aflatoxin B1  (EXP,ISO)
arsane  (EXP)
arsenic atom  (EXP)
arsenous acid  (EXP)
Azaspiracid  (EXP)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (EXP)
bisphenol A  (ISO)
bromobenzene  (ISO)
caffeine  (ISO)
calcitriol  (EXP)
carbon nanotube  (ISO)
chloroprene  (ISO)
choline  (ISO)
ciguatoxin CTX1B  (ISO)
cisplatin  (EXP)
clobetasol  (ISO)
copper(II) sulfate  (EXP)
diarsenic trioxide  (EXP)
dibutyl phthalate  (ISO)
difenoconazole  (ISO)
dinophysistoxin 1  (EXP)
disodium selenite  (EXP)
doxorubicin  (EXP)
endosulfan  (ISO)
ferroheme b  (ISO)
fluoranthene  (ISO)
folic acid  (ISO)
furan  (ISO)
heme b  (ISO)
ketoconazole  (ISO)
L-methionine  (ISO)
methoxyacetic acid  (ISO)
methylmercury chloride  (EXP,ISO)
miconazole  (ISO)
Monobutylphthalate  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
nickel atom  (EXP)
okadaic acid  (EXP)
paracetamol  (ISO)
perfluorononanoic acid  (EXP)
phenobarbital  (ISO)
pirinixic acid  (ISO)
pravastatin  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
propanal  (EXP)
propiconazole  (ISO)
rac-lactic acid  (EXP)
resveratrol  (EXP)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
succimer  (ISO)
tacrolimus hydrate  (ISO)
tamoxifen  (ISO)
testosterone  (EXP)
tetrachloromethane  (ISO)
trichostatin A  (EXP)
trimellitic anhydride  (ISO)
troglitazone  (ISO)
trovafloxacin  (ISO)
valproic acid  (EXP)
vancomycin  (ISO)
vinclozolin  (ISO)
Yessotoxin  (EXP)
zaragozic acid A  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
1. GOA_HUMAN data from the GO Consortium
2. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:12011452   PMID:12477932   PMID:14702039   PMID:15342556   PMID:15760897   PMID:16579971   PMID:17213182   PMID:18403318   PMID:19913121   PMID:20059974   PMID:20379614  
PMID:20628086   PMID:21767660   PMID:21873635   PMID:21900492   PMID:23033213   PMID:24440759   PMID:25231870   PMID:28209730   PMID:31607485   PMID:31917335   PMID:32296183  


Genomics

Comparative Map Data
STARD4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl5111,496,033 - 111,512,590 (-)EnsemblGRCh38hg38GRCh38
GRCh385111,491,422 - 111,512,567 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh375110,831,731 - 110,848,233 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365110,861,921 - 110,876,056 (-)NCBINCBI36hg18NCBI36
Build 345110,861,920 - 110,876,056NCBI
Celera5106,779,623 - 106,793,758 (-)NCBI
Cytogenetic Map5q22.1NCBI
HuRef5106,012,693 - 106,026,827 (-)NCBIHuRef
CHM1_15110,265,025 - 110,281,589 (-)NCBICHM1_1
Stard4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391833,332,191 - 33,346,937 (-)NCBIGRCm39mm39
GRCm39 Ensembl1833,332,408 - 33,346,915 (-)Ensembl
GRCm381833,199,138 - 33,213,862 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1833,199,355 - 33,213,862 (-)EnsemblGRCm38mm10GRCm38
MGSCv371833,361,075 - 33,373,470 (-)NCBIGRCm37mm9NCBIm37
MGSCv361833,326,232 - 33,338,627 (-)NCBImm8
Celera1833,649,468 - 33,662,093 (-)NCBICelera
Cytogenetic Map18B1NCBI
cM Map1818.18NCBI
Stard4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21824,814,683 - 24,830,024 (-)NCBI
Rnor_6.0 Ensembl1825,984,638 - 25,997,555 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01825,982,210 - 25,997,555 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01825,699,344 - 25,712,261 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41825,638,433 - 25,653,958 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11825,669,531 - 25,740,871 (-)NCBI
Celera1824,564,822 - 24,577,739 (-)NCBICelera
Cytogenetic Map18p12NCBI
Stard4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554183,638,399 - 3,648,402 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554183,637,390 - 3,652,054 (+)NCBIChiLan1.0ChiLan1.0
STARD4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.15112,658,743 - 112,675,165 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5112,657,516 - 112,675,165 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v05106,855,990 - 106,873,384 (-)NCBIMhudiblu_PPA_v0panPan3
STARD4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl31,154,358 - 1,170,469 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.131,154,358 - 1,171,248 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Stard4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365315,865,840 - 5,877,591 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
STARD4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2116,235,816 - 116,257,041 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12116,235,821 - 116,257,143 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22120,830,521 - 120,845,745 (-)NCBISscrofa10.2Sscrofa10.2susScr3
STARD4
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12314,842,152 - 14,854,675 (-)NCBI
ChlSab1.1 Ensembl2314,842,286 - 14,854,702 (-)Ensembl
Stard4
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474329,278,327 - 29,298,050 (-)NCBI

Position Markers
RH103232  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375110,832,100 - 110,832,235UniSTSGRCh37
Build 365110,859,999 - 110,860,134RGDNCBI36
Celera5106,777,701 - 106,777,836RGD
Cytogenetic Map5q22.1UniSTS
HuRef5106,010,771 - 106,010,906UniSTS
GeneMap99-GB4 RH Map5465.41UniSTS
RH103311  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375110,832,885 - 110,833,024UniSTSGRCh37
Build 365110,860,784 - 110,860,923RGDNCBI36
Celera5106,778,486 - 106,778,625RGD
Cytogenetic Map5q22.1UniSTS
HuRef5106,011,556 - 106,011,695UniSTS
GeneMap99-GB4 RH Map5465.38UniSTS
STARD4__5333  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375110,833,929 - 110,834,687UniSTSGRCh37
Build 365110,861,828 - 110,862,586RGDNCBI36
Celera5106,779,530 - 106,780,288RGD
HuRef5106,012,600 - 106,013,358UniSTS
SHGC-67307  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map15q22.3UniSTS
Cytogenetic Map20q13.3UniSTS
Cytogenetic Map7q11.23UniSTS
Cytogenetic Map7p13UniSTS
Cytogenetic Map19q13.32UniSTS
Cytogenetic Map19q13.43UniSTS
Cytogenetic Map3q21.2UniSTS
Cytogenetic Map3p21.3UniSTS
Cytogenetic Map18q11.2UniSTS
Cytogenetic Map19q13.3UniSTS
Cytogenetic MapXp11.3UniSTS
Cytogenetic Map7q21.2UniSTS
Cytogenetic Map13q14UniSTS
Cytogenetic Map19p13.3UniSTS
Cytogenetic Map18pter-p11.3UniSTS
Cytogenetic Map7p22.2UniSTS
Cytogenetic Map8q24.3UniSTS
Cytogenetic Map22q11.21UniSTS
Cytogenetic Map4q13.1UniSTS
Cytogenetic Map6p25UniSTS
Cytogenetic Map13q34UniSTS
Cytogenetic Map8q24.22UniSTS
Cytogenetic Map16q21UniSTS
Cytogenetic Map1p35.2UniSTS
Cytogenetic Map1q25.1UniSTS
Cytogenetic Map12q13.3UniSTS
Cytogenetic Map11q13UniSTS
Cytogenetic Map8q21.1UniSTS
Cytogenetic Map19q13.12UniSTS
Cytogenetic Map1p13.3UniSTS
Cytogenetic Map6q22.31UniSTS
Cytogenetic Map7p11.2UniSTS
Cytogenetic Map7q34UniSTS
Cytogenetic Map12q24.31UniSTS
Cytogenetic Map12q24.23UniSTS
Cytogenetic Map9p13.3UniSTS
Cytogenetic Map3p21.1UniSTS
Cytogenetic Map21q22.3UniSTS
Cytogenetic Map2q24.2UniSTS
Cytogenetic Map2p25.1-p24.1UniSTS
Cytogenetic Map5q32UniSTS
Cytogenetic Map5q31UniSTS
Cytogenetic Map19q13.4UniSTS
Cytogenetic Map16p13.3UniSTS
Cytogenetic Map16q22.2UniSTS
Cytogenetic Map1q32.2-q41UniSTS
Cytogenetic Map17q21.31UniSTS
Cytogenetic Map14q12UniSTS
Cytogenetic Map16q24.3UniSTS
Cytogenetic Map17q24.1UniSTS
Cytogenetic Map22q13.1UniSTS
Cytogenetic Map16p13UniSTS
Cytogenetic Map1q32UniSTS
Cytogenetic MapXp22.3UniSTS
Cytogenetic Map14q11.2UniSTS
Cytogenetic Map6p22.3UniSTS
Cytogenetic Map6p25.2UniSTS
Cytogenetic Map14q22.1UniSTS
Cytogenetic Map1p34.3UniSTS
Cytogenetic Map7q22.1UniSTS
Cytogenetic Map7p15.3UniSTS
Cytogenetic Map1q25.3UniSTS
Cytogenetic Map15q22.2UniSTS
Cytogenetic Map20q12UniSTS
Cytogenetic Map4p15.32UniSTS
Cytogenetic Map19q13.42UniSTS
Cytogenetic Map12q24.13UniSTS
Cytogenetic Map20q11.22UniSTS
Cytogenetic Map6p12.3UniSTS
Cytogenetic Map7q33UniSTS
Cytogenetic Map15q13.2UniSTS
Cytogenetic Map8q22.1UniSTS
Cytogenetic Map17q21UniSTS
Cytogenetic Map22q11.1UniSTS
Cytogenetic Map7q22UniSTS
Cytogenetic Map6q21UniSTS
Cytogenetic Map1p36.13UniSTS
Cytogenetic Map5p13.3UniSTS
Cytogenetic Map2p23.3UniSTS
Cytogenetic Map19q13UniSTS
Cytogenetic Map4q26UniSTS
Cytogenetic Map10q11.23UniSTS
Cytogenetic Map16p13.12UniSTS
Cytogenetic Map17q12UniSTS
Cytogenetic Map16q23.1UniSTS
Cytogenetic Map19p13.2UniSTS
Cytogenetic Map15q15.3UniSTS
Cytogenetic Map2q35UniSTS
Cytogenetic Map22q13.2UniSTS
Cytogenetic Map18q21.32UniSTS
Cytogenetic Map5q22.1UniSTS
Cytogenetic Map1p36.12UniSTS
Cytogenetic Map14q32.12UniSTS
Cytogenetic Map12q13UniSTS
Cytogenetic Map11q13.1UniSTS
Cytogenetic Map14q32.31UniSTS
Cytogenetic Map17q21.2UniSTS
Cytogenetic Map11q13.5UniSTS
Cytogenetic Map15q25.2UniSTS
Cytogenetic Map22q12.1UniSTS
Cytogenetic Map7p14.3UniSTS
Cytogenetic Map20q13.33UniSTS
Cytogenetic Map1p36.21UniSTS
TNG Radiation Hybrid Map41213.0UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:5147
Count of miRNA genes:1114
Interacting mature miRNAs:1358
Transcripts:ENST00000296632, ENST00000455172, ENST00000502322, ENST00000502931, ENST00000505803, ENST00000508215, ENST00000509887, ENST00000510346, ENST00000511137, ENST00000511436, ENST00000511569, ENST00000512160
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High 1
Medium 617 1073 908 259 995 235 1223 100 1919 139 638 1214 35 172 880 6
Low 1822 1790 817 365 832 230 2910 1883 1813 275 817 395 139 1 1032 1698 2
Below cutoff 128 1 124 222 214 2 3 3 2 210

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001308056 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001308057 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001308058 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001308059 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001308060 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001308061 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_139164 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_131752 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_131753 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_131754 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017009041 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017009042 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017009043 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017009044 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024454364 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001742000 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC011422 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF480299 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF480300 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK026207 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK054566 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK125317 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK290312 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK308851 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK310848 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK315863 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK315869 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL710253 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL832599 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC019632 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC042956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BI091150 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BP234859 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BP247836 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BU607573 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471086 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DB475661 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DT220890 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000296632   ⟹   ENSP00000296632
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl5111,496,033 - 111,512,535 (-)Ensembl
RefSeq Acc Id: ENST00000455172   ⟹   ENSP00000407063
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl5111,500,988 - 111,512,512 (-)Ensembl
RefSeq Acc Id: ENST00000502322   ⟹   ENSP00000427639
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl5111,500,147 - 111,512,590 (-)Ensembl
RefSeq Acc Id: ENST00000502931
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl5111,499,585 - 111,512,535 (-)Ensembl
RefSeq Acc Id: ENST00000505803   ⟹   ENSP00000427478
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl5111,499,882 - 111,512,562 (-)Ensembl
RefSeq Acc Id: ENST00000508215
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl5111,506,216 - 111,512,510 (-)Ensembl
RefSeq Acc Id: ENST00000509887   ⟹   ENSP00000425308
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl5111,500,246 - 111,512,535 (-)Ensembl
RefSeq Acc Id: ENST00000510346
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl5111,500,631 - 111,512,471 (-)Ensembl
RefSeq Acc Id: ENST00000511137   ⟹   ENSP00000425014
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl5111,499,402 - 111,512,535 (-)Ensembl
RefSeq Acc Id: ENST00000511436
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl5111,500,609 - 111,512,535 (-)Ensembl
RefSeq Acc Id: ENST00000511569
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl5111,500,464 - 111,512,535 (-)Ensembl
RefSeq Acc Id: ENST00000512160   ⟹   ENSP00000426148
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl5111,496,947 - 111,512,535 (-)Ensembl
RefSeq Acc Id: NM_001308056   ⟹   NP_001294985
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385111,496,033 - 111,512,535 (-)NCBI
CHM1_15110,265,025 - 110,281,589 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001308057   ⟹   NP_001294986
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385111,500,165 - 111,512,535 (-)NCBI
CHM1_15110,269,139 - 110,281,589 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001308058   ⟹   NP_001294987
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385111,500,165 - 111,512,535 (-)NCBI
CHM1_15110,269,139 - 110,281,589 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001308059   ⟹   NP_001294988
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385111,496,033 - 111,512,535 (-)NCBI
CHM1_15110,265,025 - 110,281,589 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001308060   ⟹   NP_001294989
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385111,496,033 - 111,512,535 (-)NCBI
CHM1_15110,265,025 - 110,281,589 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001308061   ⟹   NP_001294990
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385111,496,033 - 111,512,535 (-)NCBI
CHM1_15110,265,025 - 110,281,589 (-)NCBI
Sequence:
RefSeq Acc Id: NM_139164   ⟹   NP_631903
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385111,496,033 - 111,512,535 (-)NCBI
GRCh375110,831,731 - 110,848,234 (-)NCBI
Build 365110,861,921 - 110,876,056 (-)NCBI Archive
Celera5106,779,623 - 106,793,758 (-)RGD
HuRef5106,012,693 - 106,026,827 (-)ENTREZGENE
CHM1_15110,265,025 - 110,281,589 (-)NCBI
Sequence:
RefSeq Acc Id: NR_131752
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385111,500,165 - 111,512,535 (-)NCBI
CHM1_15110,269,139 - 110,281,589 (-)NCBI
Sequence:
RefSeq Acc Id: NR_131753
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385111,500,165 - 111,512,535 (-)NCBI
CHM1_15110,269,139 - 110,281,589 (-)NCBI
Sequence:
RefSeq Acc Id: NR_131754
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385111,496,033 - 111,512,535 (-)NCBI
CHM1_15110,265,025 - 110,281,589 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017009041   ⟹   XP_016864530
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385111,491,422 - 111,512,535 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017009042   ⟹   XP_016864531
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385111,491,422 - 111,512,535 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017009043   ⟹   XP_016864532
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385111,491,422 - 111,512,567 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017009044   ⟹   XP_016864533
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385111,491,422 - 111,512,510 (-)NCBI
Sequence:
RefSeq Acc Id: XM_024454364   ⟹   XP_024310132
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385111,500,297 - 111,512,536 (-)NCBI
Sequence:
RefSeq Acc Id: XR_001742000
RefSeq Status:
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385111,491,422 - 111,512,536 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_631903   ⟸   NM_139164
- Peptide Label: isoform a
- UniProtKB: Q96DR4 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001294985   ⟸   NM_001308056
- Peptide Label: isoform a
- UniProtKB: Q96DR4 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001294989   ⟸   NM_001308060
- Peptide Label: isoform d
- UniProtKB: Q96DR4 (UniProtKB/Swiss-Prot),   B0AZS2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001294990   ⟸   NM_001308061
- Peptide Label: isoform c
- UniProtKB: Q96DR4 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001294988   ⟸   NM_001308059
- Peptide Label: isoform c
- UniProtKB: Q96DR4 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001294987   ⟸   NM_001308058
- Peptide Label: isoform b
- UniProtKB: Q96DR4 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001294986   ⟸   NM_001308057
- Peptide Label: isoform b
- UniProtKB: Q96DR4 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_016864532   ⟸   XM_017009043
- Peptide Label: isoform X2
- UniProtKB: B0AZS2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_016864531   ⟸   XM_017009042
- Peptide Label: isoform X2
- UniProtKB: B0AZS2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_016864530   ⟸   XM_017009041
- Peptide Label: isoform X2
- UniProtKB: B0AZS2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_016864533   ⟸   XM_017009044
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_024310132   ⟸   XM_024454364
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSP00000427639   ⟸   ENST00000502322
RefSeq Acc Id: ENSP00000427478   ⟸   ENST00000505803
RefSeq Acc Id: ENSP00000296632   ⟸   ENST00000296632
RefSeq Acc Id: ENSP00000407063   ⟸   ENST00000455172
RefSeq Acc Id: ENSP00000425308   ⟸   ENST00000509887
RefSeq Acc Id: ENSP00000425014   ⟸   ENST00000511137
RefSeq Acc Id: ENSP00000426148   ⟸   ENST00000512160
Protein Domains
START

Promoters
RGD ID:6815527
Promoter ID:HG_MRA:12855
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:K562
Transcripts:AK026207
Position:
Human AssemblyChrPosition (strand)Source
Build 365110,861,596 - 110,862,096 (-)MPROMDB
RGD ID:6803009
Promoter ID:HG_KWN:50813
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:OTTHUMT00000250720,   UC003KPI.1,   UC003KPJ.2,   UC010JBW.1,   UC010JBX.1
Position:
Human AssemblyChrPosition (strand)Source
Build 365110,875,936 - 110,876,642 (-)MPROMDB
RGD ID:6870250
Promoter ID:EPDNEW_H8290
Type:initiation region
Name:STARD4_1
Description:StAR related lipid transfer domain containing 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh385111,512,535 - 111,512,595EPDNEW

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 5q15-22.3(chr5:96454445-114050905)x3 copy number gain See cases [RCV000051841] Chr5:96454445..114050905 [GRCh38]
Chr5:95790149..113386602 [GRCh37]
Chr5:95815905..113414501 [NCBI36]
Chr5:5q15-22.3
pathogenic
GRCh38/hg38 5q22.1(chr5:110564896-111731572)x3 copy number gain See cases [RCV000053289] Chr5:110564896..111731572 [GRCh38]
Chr5:109900597..111067269 [GRCh37]
Chr5:109928496..111095168 [NCBI36]
Chr5:5q22.1
uncertain significance
GRCh38/hg38 5q21.1-22.2(chr5:102373396-113594030)x1 copy number loss See cases [RCV000053523] Chr5:102373396..113594030 [GRCh38]
Chr5:101709100..112929727 [GRCh37]
Chr5:101736999..112957626 [NCBI36]
Chr5:5q21.1-22.2
pathogenic
GRCh38/hg38 5q21.3-33.2(chr5:106619588-156124387)x1 copy number loss See cases [RCV000053524] Chr5:106619588..156124387 [GRCh38]
Chr5:105955289..155551397 [GRCh37]
Chr5:105983188..155483975 [NCBI36]
Chr5:5q21.3-33.2
pathogenic
GRCh38/hg38 5q21.3-23.1(chr5:108585264-116815075)x1 copy number loss See cases [RCV000133813] Chr5:108585264..116815075 [GRCh38]
Chr5:107920965..116150771 [GRCh37]
Chr5:107948864..116178670 [NCBI36]
Chr5:5q21.3-23.1
pathogenic
GRCh38/hg38 5q21.3-23.1(chr5:107002209-118025316)x1 copy number loss See cases [RCV000135699] Chr5:107002209..118025316 [GRCh38]
Chr5:106337910..117361011 [GRCh37]
Chr5:106365809..117388910 [NCBI36]
Chr5:5q21.3-23.1
pathogenic
GRCh38/hg38 5q22.1-23.2(chr5:111463016-127193038)x1 copy number loss See cases [RCV000135549] Chr5:111463016..127193038 [GRCh38]
Chr5:110798714..126528730 [GRCh37]
Chr5:110826613..126556629 [NCBI36]
Chr5:5q22.1-23.2
pathogenic
GRCh38/hg38 5q22.1-23.3(chr5:110687442-130103838)x1 copy number loss See cases [RCV000139235] Chr5:110687442..130103838 [GRCh38]
Chr5:110023143..129439531 [GRCh37]
Chr5:110051042..129467430 [NCBI36]
Chr5:5q22.1-23.3
pathogenic|uncertain significance
GRCh38/hg38 5q14.3-23.3(chr5:90374606-128076423)x1 copy number loss See cases [RCV000139893] Chr5:90374606..128076423 [GRCh38]
Chr5:89670423..127412115 [GRCh37]
Chr5:89706179..127440014 [NCBI36]
Chr5:5q14.3-23.3
pathogenic
GRCh38/hg38 5q14.3-23.1(chr5:92899734-119614119)x1 copy number loss See cases [RCV000141252] Chr5:92899734..119614119 [GRCh38]
Chr5:92235441..118949814 [GRCh37]
Chr5:92261197..118977713 [NCBI36]
Chr5:5q14.3-23.1
pathogenic
GRCh38/hg38 5q22.1(chr5:110469276-111738442)x1 copy number loss See cases [RCV000141870] Chr5:110469276..111738442 [GRCh38]
Chr5:109804977..111074139 [GRCh37]
Chr5:109832876..111102038 [NCBI36]
Chr5:5q22.1
uncertain significance
GRCh38/hg38 5q21.3-22.2(chr5:106586078-113006585)x1 copy number loss See cases [RCV000142171] Chr5:106586078..113006585 [GRCh38]
Chr5:105921779..112342282 [GRCh37]
Chr5:105949678..112370181 [NCBI36]
Chr5:5q21.3-22.2
pathogenic
GRCh38/hg38 5q21.3-23.2(chr5:108308463-125777797)x1 copy number loss See cases [RCV000143326] Chr5:108308463..125777797 [GRCh38]
Chr5:107644164..125113490 [GRCh37]
Chr5:107672063..125141389 [NCBI36]
Chr5:5q21.3-23.2
pathogenic
GRCh38/hg38 5q15-22.2(chr5:93193104-113287795)x1 copy number loss See cases [RCV000143249] Chr5:93193104..113287795 [GRCh38]
Chr5:92528810..112623492 [GRCh37]
Chr5:92554566..112651391 [NCBI36]
Chr5:5q15-22.2
pathogenic
GRCh38/hg38 5q14.3-31.1(chr5:91411708-131319563)x1 copy number loss See cases [RCV000143746] Chr5:91411708..131319563 [GRCh38]
Chr5:90707525..130655256 [GRCh37]
Chr5:90743281..130683155 [NCBI36]
Chr5:5q14.3-31.1
pathogenic
GRCh37/hg19 5q15-35.3(chr5:94844077-178830410)x3 copy number gain not provided [RCV000487658] Chr5:94844077..178830410 [GRCh37]
Chr5:5q15-35.3
likely benign
NC_000005.9:g.(?_86400000)_(154000000_?)del deletion Hereditary cancer-predisposing syndrome [RCV000554476] Chr5:86400000..154000000 [GRCh37]
Chr5:5q14.3-33.2
pathogenic
GRCh37/hg19 5q22.1-23.2(chr5:110407606-122522885)x1 copy number loss See cases [RCV000446959] Chr5:110407606..122522885 [GRCh37]
Chr5:5q22.1-23.2
pathogenic
GRCh37/hg19 5q21.1-23.2(chr5:100607918-125900735)x1 copy number loss See cases [RCV000445968] Chr5:100607918..125900735 [GRCh37]
Chr5:5q21.1-23.2
pathogenic
GRCh37/hg19 5p15.33-q35.3(chr5:113577-180719789) copy number gain See cases [RCV000510723] Chr5:113577..180719789 [GRCh37]
Chr5:5p15.33-q35.3
pathogenic
GRCh37/hg19 5q21.3-35.3(chr5:106716357-180687338)x3 copy number gain See cases [RCV000448245] Chr5:106716357..180687338 [GRCh37]
Chr5:5q21.3-35.3
pathogenic
GRCh37/hg19 5q21.3-22.1(chr5:109146807-111474789)x4 copy number gain See cases [RCV000510369] Chr5:109146807..111474789 [GRCh37]
Chr5:5q21.3-22.1
uncertain significance
GRCh37/hg19 5p15.1-q35.2(chr5:17628741-176575720)x1 copy number loss See cases [RCV000511978] Chr5:17628741..176575720 [GRCh37]
Chr5:5p15.1-q35.2
pathogenic
GRCh37/hg19 5p15.33-q35.3(chr5:113577-180719789)x3 copy number gain See cases [RCV000512039] Chr5:113577..180719789 [GRCh37]
Chr5:5p15.33-q35.3
pathogenic
GRCh37/hg19 5p15.33-q35.3(chr5:13648-180905029)x3 copy number gain not provided [RCV000744317] Chr5:13648..180905029 [GRCh37]
Chr5:5p15.33-q35.3
pathogenic
GRCh37/hg19 5p15.33-q35.3(chr5:25328-180693344)x3 copy number gain not provided [RCV000744323] Chr5:25328..180693344 [GRCh37]
Chr5:5p15.33-q35.3
pathogenic
GRCh37/hg19 5q22.1(chr5:110813657-111495150)x3 copy number gain not provided [RCV000745066] Chr5:110813657..111495150 [GRCh37]
Chr5:5q22.1
benign
Single allele deletion Neurodevelopmental disorder [RCV000787436] Chr5:14685137..149511942 [GRCh37]
Chr5:5p15.2-q32
uncertain significance
GRCh37/hg19 5q21.3-23.1(chr5:108304806-121335239)x1 copy number loss not provided [RCV000846246] Chr5:108304806..121335239 [GRCh37]
Chr5:5q21.3-23.1
pathogenic
GRCh37/hg19 5q14.3-23.3(chr5:89949118-129317455)x3 copy number gain not provided [RCV000849289] Chr5:89949118..129317455 [GRCh37]
Chr5:5q14.3-23.3
pathogenic

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:18058 AgrOrtholog
COSMIC STARD4 COSMIC
Ensembl Genes ENSG00000164211 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSP00000296632 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000407063 UniProtKB/TrEMBL
  ENSP00000425014 UniProtKB/TrEMBL
  ENSP00000425308 UniProtKB/TrEMBL
  ENSP00000426148 UniProtKB/TrEMBL
  ENSP00000427478 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000427639 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000296632 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000455172 UniProtKB/TrEMBL
  ENST00000502322 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000505803 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000509887 ENTREZGENE, UniProtKB/TrEMBL
  ENST00000511137 UniProtKB/TrEMBL
  ENST00000512160 UniProtKB/TrEMBL
Gene3D-CATH 3.30.530.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000164211 GTEx
HGNC ID HGNC:18058 ENTREZGENE
Human Proteome Map STARD4 Human Proteome Map
InterPro StAR-like UniProtKB/TrEMBL
  StarD4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  START-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  START_lipid-bd_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:134429 UniProtKB/Swiss-Prot
NCBI Gene 134429 ENTREZGENE
OMIM 607049 OMIM
PANTHER PTHR47006 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam START UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA38284 PharmGKB
PRINTS STARPROTEIN UniProtKB/TrEMBL
PROSITE START UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART START UniProtKB/Swiss-Prot
UniProt B0AZS2 ENTREZGENE, UniProtKB/TrEMBL
  D6RDM5_HUMAN UniProtKB/TrEMBL
  D6REN7_HUMAN UniProtKB/TrEMBL
  Q96DR4 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q86TN9 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-24 STARD4  StAR related lipid transfer domain containing 4  STARD4  StAR-related lipid transfer domain containing 4  Symbol and/or name change 5135510 APPROVED
2015-11-10 STARD4  StAR-related lipid transfer domain containing 4  STARD4  StAR-related lipid transfer (START) domain containing 4  Symbol and/or name change 5135510 APPROVED