Slc27a1 (solute carrier family 27 member 1) - Rat Genome Database

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Gene: Slc27a1 (solute carrier family 27 member 1) Rattus norvegicus
Analyze
Symbol: Slc27a1
Name: solute carrier family 27 member 1
RGD ID: 620927
Description: Predicted to enable several functions, including fatty acid ligase activity; identical protein binding activity; and monocarboxylic acid transmembrane transporter activity. Predicted to be involved in several processes, including cellular response to hormone stimulus; glycerophospholipid biosynthetic process; and lipid transport. Predicted to act upstream of or within long-chain fatty acid transport. Located in caveola and mitochondrion. Colocalizes with mitochondrial inner membrane. Biomarker of familial hyperlipidemia; glucose intolerance; hyperinsulinism; myocardial infarction; and obesity. Orthologous to human SLC27A1 (solute carrier family 27 member 1); PARTICIPATES IN eicosanoid signaling pathway via peroxisome proliferator-activated receptor gamma; INTERACTS WITH 1,1-dichloroethene; 2,3,7,8-tetrachlorodibenzodioxine; 2-Ethylhexanoic acid.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: FATP; FATP-1; fatty acid transport protein; fatty acid transport protein 1; long-chain fatty acid transport protein 1; solute carrier family 27 (fatty acid transporter), member 1; solute carrier family 27, member 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21618,278,984 - 18,300,173 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1618,278,984 - 18,296,063 (+)Ensembl
Rnor_6.01619,997,823 - 20,016,193 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1619,999,112 - 20,016,190 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01619,859,540 - 19,880,871 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41618,769,909 - 18,786,988 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11618,769,906 - 18,786,985 (+)NCBI
Celera1618,482,929 - 18,499,970 (+)NCBICelera
Cytogenetic Map16p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (EXP)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-Ethylhexanoic acid  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
3-Iodothyronamine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methylcholanthrene  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime  (ISO)
9-cis-retinoic acid  (EXP,ISO)
actinomycin D  (EXP,ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (EXP)
ammonium chloride  (EXP)
anthra[1,9-cd]pyrazol-6(2H)-one  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (ISO)
beta-hexachlorocyclohexane  (ISO)
bexarotene  (EXP,ISO)
bezafibrate  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
calcitriol  (ISO)
captan  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
copper(II) sulfate  (ISO)
dexamethasone  (ISO)
dextran sulfate  (ISO)
dibutyl phthalate  (EXP)
doxorubicin  (EXP,ISO)
ethanol  (ISO)
farnesol  (ISO)
fenofibrate  (ISO)
flutamide  (EXP)
folic acid  (ISO)
folpet  (ISO)
genistein  (EXP)
gentamycin  (EXP)
GW 4064  (ISO)
GW 7647  (ISO)
ivermectin  (ISO)
lead(0)  (ISO)
lead(2+)  (ISO)
lipopolysaccharide  (ISO)
methamphetamine  (ISO)
methotrexate  (ISO)
methoxychlor  (EXP)
mono(2-ethylhexyl) phthalate  (EXP)
monosodium L-glutamate  (ISO)
nickel atom  (ISO)
oleic acid  (ISO)
paracetamol  (EXP,ISO)
perfluorododecanoic acid  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
perfluoroundecanoic acid  (ISO)
permethrin  (EXP)
phenformin  (EXP)
phenobarbital  (ISO)
pioglitazone  (ISO)
pirinixic acid  (ISO)
rebaudioside A  (ISO)
rifampicin  (ISO)
rotenone  (EXP)
silicon dioxide  (ISO)
sodium dodecyl sulfate  (ISO)
steviol  (ISO)
stevioside  (ISO)
streptozocin  (EXP)
sulforaphane  (ISO)
tamoxifen  (ISO)
temozolomide  (ISO)
testosterone  (ISO)
tetrachloroethene  (ISO)
tetrachloromethane  (EXP)
titanium dioxide  (ISO)
tributylstannane  (ISO)
trichostatin A  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vanadyl sulfate  (EXP)
vinclozolin  (EXP)
zinc atom  (EXP)
zinc(0)  (EXP)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:7954810   PMID:9671728   PMID:10593920   PMID:12235169   PMID:12533547   PMID:12566451   PMID:14991074   PMID:15496455   PMID:17130465   PMID:18258213   PMID:19523918   PMID:19560442  
PMID:19946888   PMID:20667975   PMID:21395585   PMID:21442160   PMID:28035674   PMID:28178239   PMID:30053369   PMID:31091338  


Genomics

Comparative Map Data
Slc27a1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21618,278,984 - 18,300,173 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1618,278,984 - 18,296,063 (+)Ensembl
Rnor_6.01619,997,823 - 20,016,193 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1619,999,112 - 20,016,190 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01619,859,540 - 19,880,871 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41618,769,909 - 18,786,988 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11618,769,906 - 18,786,985 (+)NCBI
Celera1618,482,929 - 18,499,970 (+)NCBICelera
Cytogenetic Map16p14NCBI
SLC27A1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381917,468,767 - 17,506,168 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1917,468,769 - 17,506,168 (+)EnsemblGRCh38hg38GRCh38
GRCh371917,581,333 - 17,616,977 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361917,442,300 - 17,477,977 (+)NCBINCBI36hg18NCBI36
Celera1917,482,907 - 17,518,593 (+)NCBI
Cytogenetic Map19p13.11NCBI
HuRef1917,146,725 - 17,182,058 (+)NCBIHuRef
CHM1_11917,580,668 - 17,616,359 (+)NCBICHM1_1
Slc27a1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39872,021,372 - 72,039,951 (+)NCBIGRCm39mm39
GRCm39 Ensembl872,021,526 - 72,039,946 (+)Ensembl
GRCm38871,568,728 - 71,587,307 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl871,568,882 - 71,587,302 (+)EnsemblGRCm38mm10GRCm38
MGSCv37874,092,826 - 74,110,607 (+)NCBIGRCm37mm9NCBIm37
MGSCv36874,497,916 - 74,515,697 (+)NCBImm8
Celera874,083,284 - 74,101,015 (+)NCBICelera
Cytogenetic Map8B3.3NCBI
Slc27a1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955524805,014 - 821,838 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955524803,793 - 821,920 (-)NCBIChiLan1.0ChiLan1.0
SLC27A1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11917,929,785 - 17,966,171 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1917,929,785 - 17,966,171 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01916,956,000 - 16,993,429 (+)NCBIMhudiblu_PPA_v0panPan3
SLC27A1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12045,309,094 - 45,341,101 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2045,310,088 - 45,340,230 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2045,223,163 - 45,255,236 (-)NCBI
ROS_Cfam_1.02045,796,156 - 45,828,264 (-)NCBI
ROS_Cfam_1.0 Ensembl2045,796,156 - 45,829,217 (-)Ensembl
UMICH_Zoey_3.12045,032,656 - 45,064,717 (-)NCBI
UNSW_CanFamBas_1.02045,442,740 - 45,474,725 (-)NCBI
UU_Cfam_GSD_1.02045,718,788 - 45,750,750 (-)NCBI
Slc27a1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118203,877,674 - 203,901,327 (-)NCBI
SpeTri2.0NW_0049365963,426,807 - 3,451,259 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC27A1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl260,203,374 - 60,235,652 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1260,203,374 - 60,235,689 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2259,752,658 - 59,771,672 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SLC27A1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1615,967,126 - 15,995,039 (+)NCBIChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660743,430,291 - 3,458,931 (-)NCBIVero_WHO_p1.0
Slc27a1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624908531,313 - 549,570 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
RH127318  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21618,288,679 - 18,288,883 (+)MAPPERmRatBN7.2
Rnor_6.01620,008,807 - 20,009,010NCBIRnor6.0
Rnor_5.01619,869,235 - 19,869,438UniSTSRnor5.0
RGSC_v3.41618,779,604 - 18,779,807UniSTSRGSC3.4
Celera1618,492,586 - 18,492,789UniSTS
Cytogenetic Map16p14UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)16422760943025077Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16422760943025077Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)16422760943025077Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor depth of invasion (CMO:0001888)161769679182635055Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor depth of invasion (CMO:0001888)161769679182635055Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor diameter (CMO:0001889)161769679182635055Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor diameter (CMO:0001889)161769679182635055Rat
2303566Bw90Body weight QTL 902body mass (VT:0001259)body weight (CMO:0000012)16139533930Rat
631830Alc7Alcohol consumption QTL 72.9consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16126727669Rat
737819Hcas4Hepatocarcinoma susceptibility QTL 44.43liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)16422760946975965Rat
737826Alc11Alcohol consumption QTL 113.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16422760960252231Rat
631561Hcuc2Hepatic copper content QTL 22.8hepatic copper amount (VT:0003065)liver total copper weight (CMO:0001507)16139533949Rat
1354584Despr6Despair related QTL 63.10.0067locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16139533930Rat
1582235Insul8Insulin level QTL 83.30.0063blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)16126727669Rat
2307172Activ4Activity QTL 43.710.00023locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)16133418960Rat
2312660Bw95Body weight QTL 950.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)1683223659492508Rat
2312663Slep9Serum leptin concentration QTL 90.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1683223659492508Rat
2312666Insul16Insulin level QTL 160.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1683223659492508Rat
2312669Stl23Serum triglyceride level QTL 230.01blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1683223659492508Rat
631517Scl9Serum cholesterol level QTL 93.3blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)161572643321034895Rat
2302380Slep6Serum leptin concentration QTL 63.36blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)16132139025Rat
634355Rends4Renal damage susceptibility QTL 40.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)16126727669Rat
1600369Hcas8Hepatocarcinoma susceptibility QTL 8liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)16122477621Rat
1600378Arunc4Aerobic running capacity QTL 40.03exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)1638024580345693Rat
1300133Rf24Renal function QTL 243.64blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)16338015021361552Rat
1354625Despr7Despair related QTL 73.160.016locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16144977551Rat
2306902Bp339Blood pressure QTL 3390.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16338015043025077Rat
2293343Glom16Glomerulus QTL 167.4kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1683223646053497Rat
61338Bp23Blood pressure QTL 234.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16422760949227609Rat
61405Niddm6Non-insulin dependent diabetes mellitus QTL 63.660.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)16422760948972724Rat
6903319Bw114Body weight QTL 1142.70.0037body mass (VT:0001259)body weight (CMO:0000012)16143534949Rat
9590151Scort8Serum corticosterone level QTL 88.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)16130836262Rat
7411664Foco30Food consumption QTL 30110.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)16144588133Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:179
Count of miRNA genes:119
Interacting mature miRNAs:144
Transcripts:ENSRNOT00000024659
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 26 16 5 6 5 64 26 40 8
Low 1 17 41 36 13 36 8 11 10 9 1 3 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000024659   ⟹   ENSRNOP00000024659
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1618,278,984 - 18,296,063 (+)Ensembl
Rnor_6.0 Ensembl1619,999,112 - 20,016,190 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000095535   ⟹   ENSRNOP00000077487
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1618,280,289 - 18,296,063 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000101879   ⟹   ENSRNOP00000083160
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1618,279,789 - 18,296,042 (+)Ensembl
RefSeq Acc Id: NM_053580   ⟹   NP_446032
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21618,278,984 - 18,296,064 (+)NCBI
Rnor_6.01619,999,112 - 20,016,191 (+)NCBI
Rnor_5.01619,859,540 - 19,880,871 (+)NCBI
RGSC_v3.41618,769,909 - 18,786,988 (+)RGD
Celera1618,482,929 - 18,499,970 (+)RGD
Sequence:
RefSeq Acc Id: XM_006252953   ⟹   XP_006253015
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21618,280,507 - 18,296,064 (+)NCBI
Rnor_6.01620,000,567 - 20,016,193 (+)NCBI
Rnor_5.01619,859,540 - 19,880,871 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006252954   ⟹   XP_006253016
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21618,279,786 - 18,296,064 (+)NCBI
Rnor_6.01619,999,914 - 20,016,191 (+)NCBI
Rnor_5.01619,859,540 - 19,880,871 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008771156   ⟹   XP_008769378
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21618,280,393 - 18,300,173 (+)NCBI
Rnor_6.01620,000,414 - 20,016,193 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039094877   ⟹   XP_038950805
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21618,280,393 - 18,296,705 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_446032   ⟸   NM_053580
- UniProtKB: Q6GMM8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006253016   ⟸   XM_006252954
- Peptide Label: isoform X1
- UniProtKB: Q6GMM8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006253015   ⟸   XM_006252953
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_008769378   ⟸   XM_008771156
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000024659   ⟸   ENSRNOT00000024659
RefSeq Acc Id: XP_038950805   ⟸   XM_039094877
- Peptide Label: isoform X1
RefSeq Acc Id: ENSRNOP00000083160   ⟸   ENSRNOT00000101879
RefSeq Acc Id: ENSRNOP00000077487   ⟸   ENSRNOT00000095535
Protein Domains
AMP-binding

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P97849-F1-model_v2 AlphaFold P97849 1-646 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700008
Promoter ID:EPDNEW_R10530
Type:single initiation site
Name:Slc27a1_1
Description:solute carrier family 27 member 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01619,999,142 - 19,999,202EPDNEW

Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
Damaging Variants


Assembly: RGSC_v3.4

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
16 18780688 18780689 C T snv SS/JrHsdMcwi (MCW)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620927 AgrOrtholog
BioCyc Gene G2FUF-11838 BioCyc
Ensembl Genes ENSRNOG00000018170 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000024659 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000077487 ENTREZGENE
  ENSRNOP00000083160 ENTREZGENE
Ensembl Transcript ENSRNOT00000024659 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000095535 ENTREZGENE
  ENSRNOT00000101879 ENTREZGENE
Gene3D-CATH 3.30.300.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.50.12780 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7104661 IMAGE-MGC_LOAD
InterPro AMP-bd_C_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AMP-binding_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AMP-dep_Synth/Lig UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AMP-dep_Synthh-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FATP1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:94172 UniProtKB/TrEMBL
MGC_CLONE MGC:91570 IMAGE-MGC_LOAD
NCBI Gene 94172 ENTREZGENE
PANTHER PTHR43107:SF7 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam AMP-binding UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Slc27a1 PhenoGen
PROSITE AMP_BINDING UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt P97849 ENTREZGENE
  Q6GMM8 ENTREZGENE, UniProtKB/TrEMBL
  S27A1_RAT UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-24 Slc27a1  solute carrier family 27 member 1  Slc27a1  solute carrier family 27 (fatty acid transporter), member 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Slc27a1  solute carrier family 27 (fatty acid transporter), member 1    fatty acid transport protein  Name updated 1299863 APPROVED
2002-08-07 Slc27a1  fatty acid transport protein      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_process involved in myocardial fatty acid utilization 730038