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Gene: Hsd17b2 (hydroxysteroid (17-beta) dehydrogenase 2) Rattus norvegicus
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Symbol: Hsd17b2
Name: hydroxysteroid (17-beta) dehydrogenase 2
Description: Exhibits estradiol 17-beta-dehydrogenase activity and testosterone dehydrogenase (NAD+) activity. Involved in bone development; cellular response to metal ion; and steroid hormone biosynthetic process. Localizes to the intracellular membrane-bounded organelle. Orthologous to human HSD17B2 (hydroxysteroid 17-beta dehydrogenase 2); PARTICIPATES IN estradiol biosynthetic pathway; testosterone biosynthetic pathway; steroid hormone biosynthetic pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 17-beta hydroxysteroid dehydrogenase type 2; 17-beta-HSD 2; 17-beta-hydroxysteroid dehydrogenase 2; 17-beta-hydroxysteroid dehydrogenase type 2; estradiol 17-beta-dehydrogenase 2; testosterone 17-beta-dehydrogenase
Orthologs:
Homo sapiens (human) : HSD17B2 (hydroxysteroid 17-beta dehydrogenase 2)  HGNC  Alliance
Mus musculus (house mouse) : Hsd17b2 (hydroxysteroid (17-beta) dehydrogenase 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hsd17b2 (hydroxysteroid 17-beta dehydrogenase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : HSD17B2 (hydroxysteroid 17-beta dehydrogenase 2)
Canis lupus familiaris (dog) : HSD17B2 (hydroxysteroid 17-beta dehydrogenase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hsd17b2 (hydroxysteroid 17-beta dehydrogenase 2)
Sus scrofa (pig) : HSD17B2 (hydroxysteroid 17-beta dehydrogenase 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01950,246,404 - 50,317,892 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01961,033,236 - 61,101,461 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41947,729,519 - 47,802,933 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11947,734,400 - 47,807,814 (-)NCBI
Celera1945,023,173 - 45,093,239 (+)NCBICelera
Cytogenetic Map19q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


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Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
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Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
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Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Hsd17b2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621803
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.