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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:imidazole antifungal drug
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Accession:CHEBI:87069 term browser browse the term
Definition:Any imidazole antifungal agent that has been used for the treatment of fungal infections in humans or animals.
Synonyms:related_synonym: imidazole antifungal drugs


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bifonazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases activity ISO bifonazole results in decreased activity of CYP19A1 protein CTD PMID:15554355, PMID:24496634 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Cyp51 cytochrome P450, family 51 decreases activity ISO bifonazole results in decreased activity of CYP51A1 protein CTD PMID:16989930 NCBI chr 4:27,175,564...27,194,018
Ensembl chr 4:27,175,243...27,194,018
JBrowse link
butoconazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO butoconazole results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity ISO butoconazole results in increased activity of NR1I2 protein CTD PMID:25455453 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
climbazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression EXP climbazole results in increased expression of CYP2B1 mRNA; climbazole results in increased expression of CYP2B1 protein CTD PMID:11552297, PMID:11824557 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression EXP climbazole results in increased expression of CYP3A2 protein CTD PMID:11552297, PMID:11824557 NCBI chr12:11,641,500...11,677,818
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 increases expression EXP climbazole results in increased expression of CYP4A1 protein CTD PMID:11552297 NCBI chr 5:134,492,734...134,507,158
Ensembl chr 5:134,492,756...134,507,154
JBrowse link
clotrimazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions
decreases activity
ISO Clotrimazole inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
Clotrimazole results in decreased activity of ABCB11 protein
CTD PMID:24014644 NCBI chr 3:55,480,024...55,587,946
Ensembl chr 3:55,480,024...55,587,946
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A affects binding
multiple interactions
increases expression
ISO Clotrimazole binds to ABCB1 protein
Clotrimazole inhibits the reaction [ABCB1A protein results in increased secretion of fluorexon]
Clotrimazole results in increased expression of ABCB1 protein
Clotrimazole inhibits the reaction [ABCB1 protein results in increased export of Doxorubicin]; Clotrimazole inhibits the reaction [ABCB1 protein results in increased secretion of fluorexon]; Clotrimazole inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]
CTD PMID:8632764, PMID:8917702, PMID:12235267 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 increases expression ISO Clotrimazole results in increased expression of ABCC2 mRNA; Clotrimazole results in increased expression of ABCC2 protein CTD PMID:11836020 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 multiple interactions
increases expression
ISO MAPK14 promotes the reaction [Clotrimazole results in increased expression of ABCC3 mRNA]; SB 203580 inhibits the reaction [Clotrimazole results in increased expression of ABCC3 mRNA] CTD PMID:27507784 NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
JBrowse link
G Adcy9 adenylate cyclase 9 decreases activity ISO Clotrimazole results in decreased activity of ADCY9 protein CTD PMID:30607468 NCBI chr10:11,392,698...11,515,406
Ensembl chr10:11,392,625...11,512,600
JBrowse link
G Ahr aryl hydrocarbon receptor increases activity ISO Clotrimazole results in increased activity of AHR protein CTD PMID:26187274 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Aldob aldolase, fructose-bisphosphate B affects localization ISO Clotrimazole affects the localization of ALDOB protein CTD PMID:12126931 NCBI chr 5:64,805,772...64,818,813
Ensembl chr 5:64,805,773...64,818,824
JBrowse link
G Atf3 activating transcription factor 3 increases expression
multiple interactions
ISO Clotrimazole results in increased expression of ATF3 mRNA
SB 203580 inhibits the reaction [Clotrimazole results in increased expression of ATF3 mRNA]
CTD PMID:27507784, PMID:27965148 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Casp3 caspase 3 multiple interactions ISO Clotrimazole inhibits the reaction [Benzo(a)pyrene results in increased expression of CASP3 mRNA]
[S-allylcysteine co-treated with Clotrimazole] inhibits the reaction [lead acetate results in increased activity of CASP3 protein]; Clotrimazole inhibits the reaction [lead acetate results in increased activity of CASP3 protein]
CTD PMID:22033380, PMID:24239969 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 multiple interactions ISO [S-allylcysteine co-treated with Clotrimazole] inhibits the reaction [lead acetate results in increased activity of CASP8 protein]; Clotrimazole inhibits the reaction [lead acetate results in increased activity of CASP8 protein] CTD PMID:22033380 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Cat catalase multiple interactions ISO [S-allylcysteine co-treated with Clotrimazole] inhibits the reaction [lead acetate results in decreased activity of CAT protein]; Clotrimazole inhibits the reaction [lead acetate results in decreased activity of CAT protein] CTD PMID:22033380 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression ISO Clotrimazole results in decreased expression of CDK1 CTD PMID:20724915 NCBI chr20:20,576,341...20,591,510
Ensembl chr20:20,576,377...20,591,549
JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases expression ISO Clotrimazole results in decreased expression of CDK4 CTD PMID:20724915 NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A decreases expression ISO Clotrimazole results in decreased expression of CDKN1A CTD PMID:20724915 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression ISO Clotrimazole results in increased expression of CDKN1B CTD PMID:20724915 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases activity ISO Clotrimazole results in decreased activity of CYP17A1 protein CTD PMID:31330226 NCBI chr 1:266,422,127...266,429,947
Ensembl chr 1:266,422,132...266,428,239
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases activity ISO Clotrimazole results in decreased activity of CYP19A1 protein CTD PMID:15554355 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression EXP Clotrimazole results in increased expression of CYP1A1 protein CTD PMID:7986207 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression
multiple interactions
EXP Clotrimazole results in increased expression of CYP1A2 protein
Clotrimazole inhibits the reaction [CYP1A2 protein results in increased metabolism of 3-cyano-7-ethoxycoumarin]
CTD PMID:7986207, PMID:19858067 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp2a2 cytochrome P450, family 2, subfamily a, polypeptide 2 multiple interactions EXP Clotrimazole inhibits the reaction [CYP2A2 protein results in increased metabolism of 7-benzyloxyquinoline] CTD PMID:19858067 NCBI chr 1:83,744,229...83,766,490
Ensembl chr 1:83,653,234...83,766,484
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 multiple interactions
increases activity
increases expression
EXP
ISO
Clotrimazole inhibits the reaction [CYP2B1 protein results in increased metabolism of 7-benzyloxy-4-trifluoromethylcoumarin]
Clotrimazole results in increased activity of CYP2B1 protein
NR1I3 protein affects the reaction [Clotrimazole results in increased expression of CYP2B10 mRNA]
Clotrimazole results in increased expression of CYP2B1 protein
CTD PMID:1372805, PMID:7986207, PMID:12049174, PMID:19858067 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 increases expression EXP Clotrimazole results in increased expression of CYP2B2 mRNA; Clotrimazole results in increased expression of CYP2B2 protein CTD PMID:7986207, PMID:12971794 NCBI chr 1:83,103,925...83,119,578
Ensembl chr 1:83,103,925...83,119,193
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions
increases expression
increases activity
ISO Clotrimazole results in increased expression of and results in increased activity of CYP2B6 protein; Dexamethasone promotes the reaction [NR3C1 protein affects the reaction [NR1I2 protein promotes the reaction [Clotrimazole results in increased expression of CYP2B6 mRNA]]]; NR1I2 protein affects the reaction [Clotrimazole results in increased expression of and results in increased activity of CYP2B6 protein]; NR1I2 protein promotes the reaction [Clotrimazole results in increased expression of CYP2B6 mRNA]
Clotrimazole results in increased expression of CYP2B6 protein
Clotrimazole results in increased activity of CYP2B6 protein
CTD PMID:12571232, PMID:12695351, PMID:14977870 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 multiple interactions
decreases expression
EXP Clotrimazole inhibits the reaction [CYP2C11 protein results in increased metabolism of 7-methoxy-4-trifluoromethylcoumarin]
Clotrimazole results in decreased expression of CYP2C11 protein
CTD PMID:7986207, PMID:19858067 NCBI chr 1:257,676,172...258,004,428
Ensembl chr 1:257,970,345...258,004,434
JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 multiple interactions EXP Clotrimazole inhibits the reaction [CYP2C6V1 protein results in increased metabolism of 7-methoxy-4-trifluoromethylcoumarin] CTD PMID:19858067 NCBI chr 1:147,713,879...147,814,410
Ensembl chr 1:147,713,892...147,888,007
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 decreases activity ISO Clotrimazole results in decreased activity of CYP2C8 protein CTD PMID:15601807 NCBI chr 1:147,236,480...147,307,988 JBrowse link
G Cyp2d2 cytochrome P450, family 2, subfamily d, polypeptide 2 multiple interactions EXP Clotrimazole inhibits the reaction [CYP2D2 protein results in increased metabolism of 3-(2-(N,N-diethyl-N-methylammonium)ethyl)-7-methoxy-4-methylcoumarin] CTD PMID:19858067 NCBI chr 7:123,651,827...123,655,896
Ensembl chr 7:123,651,827...123,655,896
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions EXP Clotrimazole inhibits the reaction [CYP3A2 protein results in increased metabolism of 7-benzyloxyquinoline] CTD PMID:19858067 NCBI chr12:11,641,500...11,677,818
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 increases expression
multiple interactions
EXP Clotrimazole results in increased expression of CYP3A23-3A1 mRNA
Clotrimazole inhibits the reaction [CYP3A23-3A1 protein results in increased metabolism of 7-benzyloxyquinoline]
CTD PMID:12971794, PMID:16125621, PMID:19858067 NCBI chr12:11,053,888...11,082,742
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 increases expression ISO Clotrimazole results in increased expression of CYP3A5 protein CTD PMID:8632764 NCBI chr12:19,074,288...19,114,491
Ensembl chr12:19,074,583...19,114,399
JBrowse link
G Cyp51 cytochrome P450, family 51 decreases activity
decreases response to substance
ISO Clotrimazole results in decreased activity of CYP51A1 protein
CYP51A1 gene results in decreased susceptibility to Clotrimazole
CTD PMID:16989930, PMID:18694951 NCBI chr 4:27,175,564...27,194,018
Ensembl chr 4:27,175,243...27,194,018
JBrowse link
G Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 increases expression ISO Clotrimazole results in increased expression of DNAJB4 mRNA CTD PMID:27965148 NCBI chr 2:257,394,692...257,425,344
Ensembl chr 2:257,394,818...257,425,242
JBrowse link
G Eif2a eukaryotic translation initiation factor 2A multiple interactions
increases phosphorylation
ISO [Clotrimazole results in increased phosphorylation of EIF2A protein] which results in increased expression of TMEFF2 protein CTD PMID:23405127 NCBI chr 2:148,722,343...148,755,781
Ensembl chr 2:148,722,231...148,755,520
JBrowse link
G Ephx1 epoxide hydrolase 1 increases activity EXP Clotrimazole results in increased activity of EPHX1 protein CTD PMID:1372805 NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579
JBrowse link
G F2rl1 F2R like trypsin receptor 1 multiple interactions ISO Clotrimazole inhibits the reaction [F2RL1 protein results in increased transport of Chlorides] CTD PMID:11804840 NCBI chr 2:25,222,324...25,235,275
Ensembl chr 2:25,222,328...25,235,275
JBrowse link
G Fas Fas cell surface death receptor multiple interactions ISO [S-allylcysteine co-treated with Clotrimazole] inhibits the reaction [lead acetate affects the localization of and results in increased activity of FAS protein] CTD PMID:22033380 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit decreases expression ISO Clotrimazole results in decreased expression of FOS protein CTD PMID:10223459 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Gfap glial fibrillary acidic protein increases expression ISO Clotrimazole results in increased expression of GFAP protein CTD PMID:10223459 NCBI chr10:90,990,762...90,999,435
Ensembl chr10:90,990,762...90,999,506
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 multiple interactions ISO [S-allylcysteine co-treated with Clotrimazole] inhibits the reaction [lead acetate results in increased expression of GOT1 protein] CTD PMID:22033380 NCBI chr 1:263,246,248...263,269,762
Ensembl chr 1:263,246,248...263,269,762
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO [S-allylcysteine co-treated with Clotrimazole] inhibits the reaction [lead acetate results in increased expression of GPT protein] CTD PMID:22033380 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Gsta2 glutathione S-transferase alpha 2 increases expression EXP Clotrimazole results in increased expression of GSTA2 mRNA CTD PMID:12971794 NCBI chr 8:85,640,081...85,645,621 JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO Clotrimazole inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] CTD PMID:23769903 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Hk2 hexokinase 2 affects localization
decreases expression
ISO Clotrimazole affects the localization of HK2 protein
Clotrimazole results in decreased expression of HK2 mRNA
CTD PMID:20724915, PMID:25863232 NCBI chr 4:113,559,396...113,609,897
Ensembl chr 4:113,559,427...113,610,243
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 increases expression
increases secretion
ISO Clotrimazole results in increased expression of IGFBP1 mRNA
Clotrimazole results in increased secretion of IGFBP1 protein
CTD PMID:12659874 NCBI chr14:87,448,716...87,453,783
Ensembl chr14:87,448,692...87,453,785
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Clotrimazole results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
G Kcnn4 potassium calcium-activated channel subfamily N member 4 multiple interactions
decreases activity
ISO Clotrimazole inhibits the reaction [[Ionomycin co-treated with Tetraethylammonium] results in increased activity of KCNN4 protein]
[S-allylcysteine co-treated with Clotrimazole] inhibits the reaction [lead acetate results in increased activity of KCNN4 protein]; Clotrimazole inhibits the reaction [lead acetate results in increased activity of KCNN4 protein]
Clotrimazole results in decreased activity of KCNN4 protein
CTD PMID:14985237, PMID:15921678, PMID:17699636, PMID:20050851, PMID:22033380 NCBI chr 1:81,227,855...81,245,986
Ensembl chr 1:81,230,612...81,245,996
JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions ISO MAPK14 promotes the reaction [Clotrimazole results in increased expression of ABCC3 mRNA] CTD PMID:27507784 NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137
JBrowse link
G Mir96 microRNA 96 increases expression EXP Clotrimazole results in increased expression of MIR96 mRNA CTD PMID:27427493 NCBI chr 4:57,463,366...57,463,471
Ensembl chr 4:57,463,366...57,463,471
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression ISO Clotrimazole results in decreased expression of MYC protein CTD PMID:10223459 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Ncoa1 nuclear receptor coactivator 1 multiple interactions ISO Clotrimazole promotes the reaction [NR1I3 protein modified form binds to NCOA1 protein]
Clotrimazole promotes the reaction [NR1I2 protein binds to NCOA1 protein]; Clotrimazole promotes the reaction [NR1I3 protein modified form binds to NCOA1 protein]
CTD PMID:17998298, PMID:18973326, PMID:21924250 NCBI chr 6:28,677,563...28,931,844
Ensembl chr 6:28,677,540...28,931,843
JBrowse link
G Ncor1 nuclear receptor co-repressor 1 multiple interactions ISO Clotrimazole promotes the reaction [NR1I3 protein modified form binds to NCOR1 protein] CTD PMID:18973326 NCBI chr10:48,629,121...48,772,890
Ensembl chr10:48,629,121...48,772,890
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions
increases activity
increases expression
ISO
EXP
Clotrimazole binds to and results in increased activity of NR1I2 protein; Clotrimazole promotes the reaction [NR1I2 protein binds to NCOA1 protein]; Clotrimazole promotes the reaction [NR1I2 results in increased expression of CYP3A4 mRNA]; Dexamethasone promotes the reaction [NR3C1 protein affects the reaction [NR1I2 protein promotes the reaction [Clotrimazole results in increased expression of CYP2B6 mRNA]]]; NR1I2 protein affects the reaction [Clotrimazole results in increased expression of and results in increased activity of CYP2B6 protein]; NR1I2 protein promotes the reaction [Clotrimazole results in increased expression of CYP2B6 mRNA]; NR1I2 protein promotes the reaction [Clotrimazole results in increased expression of CYP3A4 mRNA]
Clotrimazole results in increased activity of NR1I2 protein
Clotrimazole results in increased expression of NR1I2 mRNA
CTD PMID:12049174, PMID:12065438, PMID:12695351, PMID:14977870, PMID:15548381, PMID:15849716, PMID:16919048, PMID:17998298, PMID:20869355, PMID:23899473, PMID:25680588, PMID:26187274, PMID:27507784, PMID:27732639, PMID:28259787 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions
decreases activity
increases activity
affects binding
ISO
EXP
1,1-bis(4-hydroxyphenyl)cyclohexane inhibits the reaction [Clotrimazole binds to NR1I3 protein]; 4,4'-hexafluorisopropylidene diphenol inhibits the reaction [Clotrimazole binds to NR1I3 protein]; androstan-3-ol inhibits the reaction [Clotrimazole binds to NR1I3 protein]; bisphenol A inhibits the reaction [Clotrimazole binds to NR1I3 protein]; bisphenol B inhibits the reaction [Clotrimazole binds to NR1I3 protein]; Clotrimazole binds to and affects the activity of NR1I3 protein; Clotrimazole binds to and results in decreased activity of NR1I3 protein; Clotrimazole binds to and results in increased activity of and results in increased localization of NR1I3 protein mutant form; Clotrimazole binds to and results in increased activity of NR1I3 protein alternative form; Clotrimazole inhibits the reaction [4-nonylphenol results in increased activity of NR1I3 protein]; Clotrimazole inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime binds to and results in increased activity of NR1I3 protein mutant form]; Clotrimazole promotes the reaction [NR1I3 protein modified form binds to NCOA1 protein]
Clotrimazole results in decreased activity of NR1I3 protein
Clotrimazole results in increased activity of NR1I3 protein; Clotrimazole results in increased activity of NR1I3 protein alternative form
Clotrimazole results in decreased activity of NR1I3 protein; Clotrimazole results in decreased activity of NR1I3 protein alternative form
Clotrimazole results in increased activity of NR1I3 protein; Clotrimazole results in increased activity of NR1I3 protein alternative form; Clotrimazole results in increased activity of NR1I3 protein mutant form
androstan-3-ol inhibits the reaction [Clotrimazole results in increased activity of NR1I3 protein mutant form]; Clotrimazole inhibits the reaction [androstan-3-ol results in decreased activity of NR1I3 protein alternative form]; Clotrimazole inhibits the reaction [Imidazoles results in decreased activity of NR1I3 protein alternative form]; Imidazoles inhibits the reaction [Clotrimazole results in increased activity of NR1I3 protein mutant form]
Clotrimazole results in increased activity of NR1I3 protein; Clotrimazole results in increased activity of NR1I3 protein mutant form
Clotrimazole promotes the reaction [NR1I3 protein modified form binds to NCOA1 protein]; Clotrimazole promotes the reaction [NR1I3 protein modified form binds to NCOR1 protein]; NR1I3 protein affects the reaction [Clotrimazole results in increased expression of CYP2B10 mRNA]
CTD PMID:12049174, PMID:15905360, PMID:16919048, PMID:18973326, PMID:20686338, PMID:20869355, PMID:21315811, PMID:21778469, PMID:21924250, PMID:23015691, PMID:23899473, PMID:25625231, PMID:26187274, PMID:27732639, PMID:31195007, PMID:31312845 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions ISO Dexamethasone promotes the reaction [NR3C1 protein affects the reaction [NR1I2 protein promotes the reaction [Clotrimazole results in increased expression of CYP2B6 mRNA]]] CTD PMID:12695351 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Odc1 ornithine decarboxylase 1 increases expression EXP Clotrimazole results in increased expression of ODC1 mRNA CTD PMID:12971794 NCBI chr 6:42,852,529...42,859,142
Ensembl chr 6:42,852,683...42,859,927
JBrowse link
G Pfkm phosphofructokinase, muscle decreases expression ISO Clotrimazole results in decreased expression of PFKM mRNA CTD PMID:25863232 NCBI chr 7:139,702,066...139,722,132
Ensembl chr 7:139,685,573...139,722,132
JBrowse link
G Pfkp phosphofructokinase, platelet affects localization ISO Clotrimazole affects the localization of PFKP protein CTD PMID:12126931 NCBI chr17:68,510,765...68,574,387
Ensembl chr17:68,511,064...68,559,471
JBrowse link
G Prdx2 peroxiredoxin 2 multiple interactions ISO [S-allylcysteine co-treated with Clotrimazole] inhibits the reaction [lead acetate affects the localization of PRDX2 protein]; [S-allylcysteine co-treated with Clotrimazole] inhibits the reaction [lead acetate promotes the reaction [PRDX2 protein binds to PRDX2 protein]]; Clotrimazole inhibits the reaction [lead acetate promotes the reaction [PRDX2 protein binds to PRDX2 protein]] CTD PMID:22033380 NCBI chr19:26,084,816...26,090,095
Ensembl chr19:26,084,903...26,090,094
JBrowse link
G Rgn regucalcin decreases expression EXP Clotrimazole results in decreased expression of RGN mRNA CTD PMID:12971794 NCBI chr  X:1,833,484...1,848,904
Ensembl chr  X:1,833,492...1,848,904
JBrowse link
G Slc19a1 solute carrier family 19 member 1 multiple interactions
decreases activity
EXP Clotrimazole inhibits the reaction [SLC19A1 protein results in increased uptake of Methotrexate]
Clotrimazole results in decreased activity of SLC19A1 protein
CTD PMID:17482559 NCBI chr20:12,334,675...12,354,517
Ensembl chr20:12,334,676...12,352,377
JBrowse link
G Smpd1 sphingomyelin phosphodiesterase 1 multiple interactions ISO [S-allylcysteine co-treated with Clotrimazole] inhibits the reaction [lead acetate results in increased activity of SMPD1 protein]; Clotrimazole inhibits the reaction [lead acetate results in increased activity of SMPD1 protein] CTD PMID:22033380 NCBI chr 1:170,383,682...170,387,525
Ensembl chr 1:170,383,682...170,387,524
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 decreases expression EXP Clotrimazole results in decreased expression of SULT1A1 mRNA CTD PMID:9566755 NCBI chr 1:198,100,586...198,104,106
Ensembl chr 1:198,100,586...198,104,109
JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 decreases expression EXP Clotrimazole results in decreased expression of SULT2A1 mRNA CTD PMID:9566755 NCBI chr 1:76,558,721...76,614,315
Ensembl chr 1:76,252,329...76,780,230
JBrowse link
G Tmeff2 transmembrane protein with EGF-like and two follistatin-like domains 2 multiple interactions ISO [Clotrimazole results in increased phosphorylation of EIF2A protein] which results in increased expression of TMEFF2 protein CTD PMID:23405127 NCBI chr 9:55,379,130...55,673,704
Ensembl chr 9:55,384,100...55,673,829
JBrowse link
G Tp53 tumor protein p53 increases expression ISO Clotrimazole results in increased expression of TP53 protein CTD PMID:10223459 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Trpm2 transient receptor potential cation channel, subfamily M, member 2 multiple interactions EXP
ISO
Clotrimazole inhibits the reaction [Adenosine Diphosphate Ribose promotes the reaction [TRPM2 protein results in increased transport of Calcium]]
[Clotrimazole results in decreased activity of TRPM2 protein] inhibits the reaction [Mustard Gas results in increased abundance of Calcium]
CTD PMID:21900507, PMID:22036725 NCBI chr20:11,434,062...11,482,880
Ensembl chr20:11,436,267...11,482,051
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 affects expression ISO Clotrimazole affects the expression of UGT1A1 mRNA CTD PMID:15849716 NCBI chr 9:95,295,701...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions
increases secretion
ISO [Clotrimazole co-treated with Imatinib Mesylate] results in increased secretion of VEGFA protein
Clotrimazole results in increased secretion of VEGFA protein
CTD PMID:25863232 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
econazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy9 adenylate cyclase 9 increases activity ISO Econazole results in increased activity of ADCY9 protein CTD PMID:30607468 NCBI chr10:11,392,698...11,515,406
Ensembl chr10:11,392,625...11,512,600
JBrowse link
G Cyp51 cytochrome P450, family 51 decreases response to substance ISO CYP51A1 gene results in decreased susceptibility to Econazole CTD PMID:18694951 NCBI chr 4:27,175,564...27,194,018
Ensembl chr 4:27,175,243...27,194,018
JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO Econazole inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] CTD PMID:23769903 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Kcna3 potassium voltage-gated channel subfamily A member 3 multiple interactions
decreases activity
ISO [Econazole results in decreased activity of KCNA3 protein] which results in decreased import of Thallium CTD PMID:21362439 NCBI chr 2:209,766,767...209,768,344
Ensembl chr 2:209,766,512...209,769,711
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity
multiple interactions
ISO Econazole results in decreased activity of KCNH2 protein
[Econazole results in decreased activity of KCNH2 protein] which results in decreased import of Thallium
CTD PMID:21362439 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
G Ncoa1 nuclear receptor coactivator 1 multiple interactions ISO Econazole promotes the reaction [NR1I2 protein binds to NCOA1 protein] CTD PMID:17998298 NCBI chr 6:28,677,563...28,931,844
Ensembl chr 6:28,677,540...28,931,843
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO Econazole binds to and results in increased activity of NR1I2 protein; Econazole promotes the reaction [NR1I2 protein binds to NCOA1 protein]; Econazole promotes the reaction [NR1I2 results in increased expression of CYP3A4 mRNA] CTD PMID:17998298 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 multiple interactions ISO [tebuconazole co-treated with Econazole] results in increased phosphorylation of PRKAA1 protein CTD PMID:30698772 NCBI chr 2:54,857,688...54,893,404
Ensembl chr 2:54,857,688...54,893,404
JBrowse link
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 multiple interactions ISO [tebuconazole co-treated with Econazole] results in increased phosphorylation of PRKAA2 protein CTD PMID:30698772 NCBI chr 5:124,568,845...124,642,569
Ensembl chr 5:124,574,079...124,642,569
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Econazole inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link
G Trpm2 transient receptor potential cation channel, subfamily M, member 2 multiple interactions ISO [Econazole results in decreased activity of TRPM2 protein] inhibits the reaction [Mustard Gas results in increased abundance of Calcium] CTD PMID:22036725 NCBI chr20:11,434,062...11,482,880
Ensembl chr20:11,436,267...11,482,051
JBrowse link
G Ulk1 unc-51 like autophagy activating kinase 1 multiple interactions ISO [tebuconazole co-treated with Econazole] results in increased phosphorylation of ULK1 protein; dorsomorphin inhibits the reaction [[tebuconazole co-treated with Econazole] results in increased phosphorylation of ULK1 protein] CTD PMID:30698772 NCBI chr12:51,908,105...51,934,704
Ensembl chr12:51,908,448...51,934,702
JBrowse link
enilconazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 decreases expression ISO enilconazole results in decreased expression of ABCB11 mRNA CTD PMID:29451352 NCBI chr 3:55,480,024...55,587,946
Ensembl chr 3:55,480,024...55,587,946
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 decreases expression ISO enilconazole results in decreased expression of ABCC2 mRNA CTD PMID:29451352 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 decreases expression ISO enilconazole results in decreased expression of ABCC3 mRNA CTD PMID:29451352 NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
JBrowse link
G Acox1 acyl-CoA oxidase 1 decreases expression ISO enilconazole results in decreased expression of ACOX1 mRNA CTD PMID:32201337 NCBI chr10:104,724,534...104,748,003
Ensembl chr10:104,722,958...104,748,050
JBrowse link
G Adk adenosine kinase increases expression ISO enilconazole results in increased expression of ADK mRNA CTD PMID:32201337 NCBI chr15:3,033,535...3,435,888
Ensembl chr15:3,033,495...3,435,888
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 decreases expression
multiple interactions
ISO enilconazole results in decreased expression of ALDH1A1 mRNA
[thiacloprid co-treated with enilconazole] results in decreased expression of ALDH1A1 mRNA
CTD PMID:32201337 NCBI chr 1:238,222,689...238,264,381
Ensembl chr 1:238,222,521...238,264,330
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member decreases expression ISO enilconazole results in decreased expression of ALDH2 mRNA CTD PMID:32201337 NCBI chr12:40,466,418...40,498,813
Ensembl chr12:40,466,495...40,498,752
JBrowse link
G Ano1 anoctamin 1 decreases expression ISO enilconazole results in decreased expression of ANO1 mRNA CTD PMID:29106682 NCBI chr 1:217,754,349...217,902,540
Ensembl chr 1:217,754,336...217,902,473
JBrowse link
G Anxa10 annexin A10 increases expression ISO enilconazole results in increased expression of ANXA10 mRNA CTD PMID:32194361 NCBI chr16:29,674,699...29,741,521
Ensembl chr16:29,674,793...29,741,465
JBrowse link
G Ar androgen receptor multiple interactions ISO Dihydrotestosterone inhibits the reaction [enilconazole results in increased activity of AR protein]; enilconazole inhibits the reaction [Dihydrotestosterone results in increased expression of AR mRNA]; enilconazole inhibits the reaction [Metribolone results in increased activity of AR protein] CTD PMID:15064155, PMID:18324785, PMID:21310686 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Arg1 arginase 1 decreases expression ISO enilconazole results in decreased expression of ARG1 mRNA CTD PMID:32194361 NCBI chr 1:21,525,421...21,537,872
Ensembl chr 1:21,525,421...21,537,863
JBrowse link
G Atp8b1 ATPase phospholipid transporting 8B1 increases expression ISO enilconazole results in increased expression of ATP8B1 mRNA CTD PMID:32201337 NCBI chr18:60,013,388...60,152,920
Ensembl chr18:60,013,382...60,095,354
JBrowse link
G Cat catalase increases expression ISO enilconazole results in increased expression of CAT mRNA CTD PMID:29451352 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases expression ISO enilconazole results in increased expression of CCL5 mRNA CTD PMID:32201337 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Ces2h carboxylesterase 2H multiple interactions
decreases expression
ISO [enilconazole co-treated with thiacloprid] results in increased expression of CES2 protein
enilconazole results in decreased expression of CES2 mRNA
CTD PMID:32201337 NCBI chr19:37,052,555...37,067,176
Ensembl chr19:37,052,556...37,067,156
JBrowse link
G Cftr CF transmembrane conductance regulator affects binding
decreases expression
ISO enilconazole binds to CFTR protein
enilconazole results in decreased expression of CFTR mRNA; enilconazole results in decreased expression of CFTR protein
CTD PMID:29106682 NCBI chr 4:42,693,263...42,860,679
Ensembl chr 4:42,692,836...42,860,676
JBrowse link
G Comt catechol-O-methyltransferase increases expression ISO enilconazole results in increased expression of COMT protein CTD PMID:32201337 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases activity ISO enilconazole results in decreased activity of CYP19A1 protein CTD PMID:10806373, PMID:15554355, PMID:26141389 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases activity
increases expression
multiple interactions
ISO enilconazole results in increased activity of CYP1A1 protein
enilconazole results in increased expression of CYP1A1 mRNA; enilconazole results in increased expression of CYP1A1 protein
enilconazole inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]
CTD PMID:19070657, PMID:21762035, PMID:32194361 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 affects expression
multiple interactions
ISO enilconazole affects the expression of CYP1A2 mRNA
[clothianidin co-treated with enilconazole] results in increased expression of CYP1A2 mRNA; [enilconazole co-treated with thiacloprid co-treated with clothianidin] results in increased expression of CYP1A2 mRNA; [thiacloprid co-treated with enilconazole] results in increased expression of CYP1A2 mRNA
CTD PMID:32201337 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression
multiple interactions
ISO enilconazole results in increased expression of CYP1B1 mRNA
[clothianidin co-treated with enilconazole] results in increased expression of CYP1B1 protein
CTD PMID:32201337 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression ISO enilconazole results in increased expression of CYP2B10 CTD PMID:27853109 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions
affects expression
ISO [enilconazole co-treated with thiacloprid] results in increased expression of CYP2B6 protein; [enilconazole co-treated with thiacloprid] results in increased expression of CYP2B9 protein; [thiacloprid co-treated with enilconazole] results in increased expression of CYP2B6 mRNA
enilconazole affects the expression of CYP2B6 mRNA
CTD PMID:32201337 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 decreases expression ISO enilconazole results in decreased expression of CYP2C19 mRNA; enilconazole results in decreased expression of CYP2C19 protein CTD PMID:32194361, PMID:32201337 NCBI chr 1:147,713,879...147,814,410
Ensembl chr 1:147,713,892...147,888,007
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions
decreases expression
ISO [clothianidin co-treated with enilconazole] results in decreased expression of CYP2E1 mRNA; [enilconazole co-treated with thiacloprid co-treated with clothianidin] results in decreased expression of CYP2E1 mRNA; [thiacloprid co-treated with enilconazole] results in decreased expression of CYP2E1 mRNA
enilconazole results in decreased expression of CYP2E1 mRNA
CTD PMID:32201337 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 increases expression
multiple interactions
ISO enilconazole results in increased expression of CYP3A5 mRNA; enilconazole results in increased expression of CYP3A5 protein
[clothianidin co-treated with enilconazole] results in increased expression of CYP3A5 protein; [enilconazole co-treated with thiacloprid] results in increased expression of CYP3A5 protein
CTD PMID:32201337 NCBI chr12:19,074,288...19,114,491
Ensembl chr12:19,074,583...19,114,399
JBrowse link
G Cyp51 cytochrome P450, family 51 decreases activity ISO enilconazole results in decreased activity of CYP51A1 protein CTD PMID:16989930 NCBI chr 4:27,175,564...27,194,018
Ensembl chr 4:27,175,243...27,194,018
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 decreases expression ISO enilconazole results in decreased expression of CYP7A1 mRNA
enilconazole results in decreased expression of CYP7A1 mRNA; enilconazole results in decreased expression of CYP7A1 protein
CTD PMID:29451352, PMID:32194361, PMID:32201337 NCBI chr 5:19,358,734...19,368,431
Ensembl chr 5:19,358,734...19,368,431
JBrowse link
G Cyp7b1 cytochrome P450 family 7 subfamily B member 1 decreases expression ISO enilconazole results in decreased expression of CYP7B1 mRNA CTD PMID:32201337 NCBI chr 2:102,701,903...102,871,257
Ensembl chr 2:102,701,903...102,871,257
JBrowse link
G Dnm1 dynamin 1 decreases expression ISO enilconazole results in decreased expression of DNM1 mRNA CTD PMID:32201337 NCBI chr 3:11,338,081...11,382,043
Ensembl chr 3:11,338,083...11,382,043
JBrowse link
G Fas Fas cell surface death receptor increases expression ISO enilconazole results in increased expression of FAS mRNA CTD PMID:32201337 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Fgf19 fibroblast growth factor 19 decreases expression ISO enilconazole results in decreased expression of FGF15 mRNA CTD PMID:29451352 NCBI chr 1:218,058,405...218,061,693
Ensembl chr 1:218,058,405...218,061,693
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 decreases expression ISO enilconazole results in decreased expression of G6PC mRNA CTD PMID:32194361, PMID:32201337 NCBI chr10:89,286,009...89,296,213
Ensembl chr10:89,285,855...89,296,213
JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression ISO enilconazole results in increased expression of GPX1 mRNA CTD PMID:29451352 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Gpx2 glutathione peroxidase 2 decreases expression ISO enilconazole results in decreased expression of GPX2 mRNA CTD PMID:29451352 NCBI chr 6:99,839,960...99,843,245
Ensembl chr 6:99,839,960...99,843,245
JBrowse link
G Gsr glutathione-disulfide reductase increases expression ISO enilconazole results in increased expression of GSR mRNA CTD PMID:29451352 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gss glutathione synthetase decreases expression ISO enilconazole results in decreased expression of GSS mRNA CTD PMID:29451352 NCBI chr 3:151,076,254...151,106,557
Ensembl chr 3:151,076,254...151,106,557
JBrowse link
G Haao 3-hydroxyanthranilate 3,4-dioxygenase decreases expression ISO enilconazole results in decreased expression of HAAO mRNA CTD PMID:32201337 NCBI chr 6:7,045,145...7,059,227
Ensembl chr 6:7,045,152...7,058,314
JBrowse link
G Ifng interferon gamma increases expression ISO enilconazole results in increased expression of IFNG mRNA CTD PMID:27393971 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il17a interleukin 17A multiple interactions ISO enilconazole inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA] CTD PMID:22289359 NCBI chr 9:26,841,299...26,844,786
Ensembl chr 9:26,841,299...26,844,786
JBrowse link
G Il1b interleukin 1 beta increases expression ISO enilconazole results in increased expression of IL1B mRNA CTD PMID:27393971 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il22 interleukin 22 increases expression ISO enilconazole results in increased expression of IL22 mRNA CTD PMID:27393971 NCBI chr 7:61,236,037...61,240,502
Ensembl chr 7:61,236,037...61,240,502
JBrowse link
G Il6 interleukin 6 increases expression ISO enilconazole results in increased expression of IL6 mRNA CTD PMID:27393971, PMID:32201337 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression ISO enilconazole results in increased expression of JUN mRNA CTD PMID:32201337 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Khk ketohexokinase decreases expression ISO enilconazole results in decreased expression of KHK mRNA CTD PMID:32201337 NCBI chr 6:26,810,577...26,821,013
Ensembl chr 6:26,810,579...26,820,959
JBrowse link
G Klf4 Kruppel like factor 4 affects expression ISO enilconazole affects the expression of KLF4 mRNA CTD PMID:29106682 NCBI chr 5:72,283,311...72,287,669
Ensembl chr 5:72,283,313...72,287,669
JBrowse link
G Lcn2 lipocalin 2 increases expression ISO enilconazole results in increased expression of LCN2 CTD PMID:27393971 NCBI chr 3:11,414,189...11,417,534
Ensembl chr 3:11,414,186...11,417,546
JBrowse link
G Lpl lipoprotein lipase increases expression ISO enilconazole results in increased expression of LPL mRNA CTD PMID:32201337 NCBI chr16:22,537,687...22,561,487
Ensembl chr16:22,537,056...22,561,496
JBrowse link
G Ly6d lymphocyte antigen 6 family member D decreases expression ISO enilconazole results in decreased expression of LY6D mRNA CTD PMID:32201337 NCBI chr 7:115,993,304...115,994,812
Ensembl chr 7:115,993,301...115,994,783
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases expression ISO enilconazole results in increased expression of MAPK8 mRNA CTD PMID:32201337 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mep1b meprin A subunit beta affects expression ISO enilconazole affects the expression of MEP1B mRNA CTD PMID:29106682 NCBI chr18:15,063,159...15,090,877
Ensembl chr18:15,063,079...15,089,988
JBrowse link
G Mlxipl MLX interacting protein-like decreases expression ISO enilconazole results in decreased expression of MLXIPL mRNA CTD PMID:32201337 NCBI chr12:24,590,645...24,619,639 JBrowse link
G Mttp microsomal triglyceride transfer protein decreases expression ISO enilconazole results in decreased expression of MTTP mRNA CTD PMID:32201337 NCBI chr 2:243,366,181...243,407,608
Ensembl chr 2:243,366,181...243,407,608
JBrowse link
G Muc1 mucin 1, cell surface associated affects expression ISO enilconazole affects the expression of MUC1 mRNA CTD PMID:29106682 NCBI chr 2:188,543,137...188,547,874
Ensembl chr 2:188,543,137...188,547,874
JBrowse link
G Muc2 mucin 2, oligomeric mucus/gel-forming affects expression ISO enilconazole affects the expression of MUC2 mRNA CTD PMID:29106682 NCBI chr 1:214,663,929...214,693,197 JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 multiple interactions
decreases expression
ISO [clothianidin co-treated with enilconazole] results in decreased expression of NR0B2 mRNA
enilconazole results in decreased expression of NR0B2 mRNA
CTD PMID:32201337 NCBI chr 5:151,776,004...151,779,319
Ensembl chr 5:151,776,004...151,779,319
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 decreases expression ISO enilconazole results in decreased expression of NR1H4 mRNA CTD PMID:29451352 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions
increases activity
ISO [enilconazole co-treated with methidathion] results in increased activity of NR1I2 protein; enilconazole binds to and results in increased activity of NR1I2 protein; enilconazole inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]
enilconazole results in increased activity of NR1I2 protein
CTD PMID:16565514, PMID:17438109, PMID:21115097, PMID:25028461, PMID:29973476 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions
affects response to substance
ISO enilconazole binds to and results in increased activity of NR1I3 protein; enilconazole inhibits the reaction [Androstane-3,17-diol binds to and results in decreased activity of NR1I3 protein]
NR1I3 protein affects the susceptibility to enilconazole
CTD PMID:18832183, PMID:27853109 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 decreases expression ISO enilconazole results in decreased expression of PDK4 mRNA CTD PMID:32201337 NCBI chr 4:30,546,772...30,556,774
Ensembl chr 4:30,546,664...30,556,814
JBrowse link
G Pnpla3 patatin-like phospholipase domain containing 3 decreases expression ISO enilconazole results in decreased expression of PNPLA3 mRNA CTD PMID:32201337 NCBI chr 7:125,034,760...125,056,165
Ensembl chr 7:125,034,764...125,055,976
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha decreases expression ISO enilconazole results in decreased expression of PPARGC1A mRNA CTD PMID:32201337 NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO [enilconazole binds to and results in decreased activity of PTGS2 protein] which results in decreased chemical synthesis of and results in decreased secretion of Prostaglandin D2 CTD PMID:26359731 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rara retinoic acid receptor, alpha increases activity ISO enilconazole results in increased activity of RARA protein CTD PMID:20143881 NCBI chr10:86,838,819...86,884,224
Ensembl chr10:86,860,685...86,884,210
JBrowse link
G Rarg retinoic acid receptor, gamma increases activity ISO enilconazole results in increased activity of RARG protein CTD PMID:20143881 NCBI chr 7:143,840,739...143,863,206
Ensembl chr 7:143,839,980...143,863,186
JBrowse link
G Retnlb resistin like beta affects expression ISO enilconazole affects the expression of RETNLB mRNA CTD PMID:29106682 NCBI chr11:54,565,471...54,567,578
Ensembl chr11:54,565,472...54,567,357
JBrowse link
G Rgcc regulator of cell cycle increases expression ISO enilconazole results in increased expression of RGCC mRNA CTD PMID:32201337 NCBI chr15:61,551,861...61,564,695
Ensembl chr15:61,551,861...61,564,695
JBrowse link
G Rora RAR-related orphan receptor A multiple interactions ISO enilconazole binds to and results in decreased activity of RORA protein CTD PMID:22289359 NCBI chr 8:75,515,886...75,616,477
Ensembl chr 8:75,516,904...75,607,212
JBrowse link
G Scd stearoyl-CoA desaturase decreases expression ISO enilconazole results in decreased expression of SCD mRNA CTD PMID:32201337 NCBI chr 1:264,159,966...264,173,061
Ensembl chr 1:264,160,129...264,172,729
JBrowse link
G Slc10a1 solute carrier family 10 member 1 decreases expression ISO enilconazole results in decreased expression of SLC10A1 mRNA CTD PMID:29451352 NCBI chr 6:104,617,730...104,631,355
Ensembl chr 6:104,617,730...104,631,355
JBrowse link
G Slc12a2 solute carrier family 12 member 2 decreases expression ISO enilconazole results in decreased expression of SLC12A2 mRNA; enilconazole results in decreased expression of SLC12A2 protein CTD PMID:29106682 NCBI chr18:52,917,124...52,985,281
Ensembl chr18:52,917,124...52,985,261
JBrowse link
G Slc26a3 solute carrier family 26 member 3 decreases expression ISO enilconazole results in decreased expression of SLC26A3 mRNA; enilconazole results in decreased expression of SLC26A3 protein CTD PMID:29106682 NCBI chr 6:50,725,085...50,766,306
Ensembl chr 6:50,725,085...50,766,300
JBrowse link
G Slc26a6 solute carrier family 26 member 6 decreases expression ISO enilconazole results in decreased expression of SLC26A6 mRNA CTD PMID:29106682 NCBI chr 8:117,648,792...117,659,376
Ensembl chr 8:117,648,745...117,659,804
JBrowse link
G Slc9a3 solute carrier family 9 member A3 decreases expression ISO enilconazole results in decreased expression of SLC9A3 mRNA CTD PMID:29106682 NCBI chr 1:31,731,652...31,777,144
Ensembl chr 1:31,734,327...31,777,070
JBrowse link
G Slco4a1 solute carrier organic anion transporter family, member 4a1 increases expression ISO enilconazole results in increased expression of SLCO4A1 mRNA CTD PMID:32201337 NCBI chr 3:175,838,994...175,857,985
Ensembl chr 3:175,838,994...175,857,983
JBrowse link
G Sod1 superoxide dismutase 1 increases expression ISO enilconazole results in increased expression of SOD1 mRNA CTD PMID:29451352 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod2 superoxide dismutase 2 decreases expression ISO enilconazole results in decreased expression of SOD2 mRNA CTD PMID:29451352 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Sult1b1 sulfotransferase family 1B member 1 decreases expression ISO enilconazole results in decreased expression of SULT1B1 mRNA CTD PMID:32201337 NCBI chr14:22,142,412...22,155,246
Ensembl chr14:22,142,364...22,155,231
JBrowse link
G Sult1c2a sulfotransferase family, cytosolic, 1C, member 2a increases expression ISO enilconazole results in increased expression of SULT1C2 mRNA CTD PMID:32201337 NCBI chr 9:4,152,588...4,168,355
Ensembl chr 9:4,152,589...4,168,221
JBrowse link
G Tff3 trefoil factor 3 decreases expression ISO enilconazole results in decreased expression of TFF3 mRNA CTD PMID:32201337 NCBI chr20:9,850,800...9,855,481
Ensembl chr20:9,850,803...9,855,481
JBrowse link
G Tnf tumor necrosis factor increases expression ISO enilconazole results in increased expression of TNF mRNA CTD PMID:27393971 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 decreases expression ISO enilconazole results in decreased expression of UGT2B7 mRNA CTD PMID:32201337 NCBI chr14:22,597,103...22,619,968 JBrowse link
isoconazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO isoconazole results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
ketoconazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin decreases expression EXP Ketoconazole results in decreased expression of A2M mRNA CTD PMID:18289764 NCBI chr 4:154,309,426...154,359,138
Ensembl chr 4:154,309,426...154,359,137
JBrowse link
G Aadat aminoadipate aminotransferase affects expression EXP Ketoconazole affects the expression of AADAT mRNA CTD PMID:18355885 NCBI chr16:32,832,001...32,868,680
Ensembl chr16:32,832,061...32,868,702
JBrowse link
G Aatf apoptosis antagonizing transcription factor decreases expression EXP Ketoconazole results in decreased expression of AATF mRNA CTD PMID:25787151 NCBI chr10:71,744,648...71,837,851
Ensembl chr10:71,744,659...71,837,851
JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 multiple interactions EXP Ketoconazole inhibits the reaction [Clofibrate results in increased expression of ABCA1 mRNA] CTD PMID:14690017 NCBI chr 5:69,857,717...69,983,042
Ensembl chr 5:69,857,771...69,983,015
JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions
decreases activity
ISO [Ketoconazole results in decreased activity of ABCB11 protein] which results in decreased export of Taurodeoxycholic Acid; Ketoconazole inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid] CTD PMID:20147439, PMID:20829430, PMID:23956101, PMID:24014644, PMID:28437613 NCBI chr 3:55,480,024...55,587,946
Ensembl chr 3:55,480,024...55,587,946
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A increases transport
multiple interactions
affects expression
decreases expression
decreases activity
ISO
EXP
ABCB1 protein results in increased transport of Ketoconazole
Ketoconazole inhibits the reaction [Genistein results in increased expression of ABCB1A mRNA]
Ketoconazole affects the expression of ABCB1 mRNA
Ketoconazole inhibits the reaction [ABCB1A protein results in increased secretion of fluorexon]; Ketoconazole inhibits the reaction [Pregnenolone Carbonitrile results in increased expression of ABCB1 mRNA]; Ketoconazole inhibits the reaction [Pregnenolone Carbonitrile results in increased expression of ABCB1 protein]
Ketoconazole results in decreased expression of ABCB1 mRNA
Ketoconazole results in decreased activity of ABCB1 protein
[Ketoconazole binds to and results in decreased activity of ABCB1 protein] which results in decreased export of Digoxin; [Ketoconazole results in decreased activity of ABCB1 protein] which results in increased uptake of Digoxin; Ketoconazole binds to and results in decreased activity of ABCB1 protein; Ketoconazole inhibits the reaction [3,3'-diindolylmethane results in increased expression of ABCB1 mRNA]; Ketoconazole inhibits the reaction [ABCB1 protein affects the transport of Digoxin]; Ketoconazole inhibits the reaction [ABCB1 protein results in increased chemical synthesis of globotriaosylceramide]; Ketoconazole inhibits the reaction [ABCB1 protein results in increased chemical synthesis of Glucosylceramides]; Ketoconazole inhibits the reaction [ABCB1 protein results in increased chemical synthesis of Lactosylceramides]; Ketoconazole inhibits the reaction [ABCB1 protein results in increased secretion of fluorexon]; Ketoconazole inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]; Ketoconazole inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]; Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [piperine results in increased expression of ABCB1 mRNA]]; Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [piperine results in increased expression of ABCB1 protein]]; Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of ABCB1 mRNA]]; Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of ABCB1 protein]]; Ketoconazole inhibits the reaction [Paclitaxel results in increased expression of ABCB1 mRNA]; Ketoconazole inhibits the reaction [Paclitaxel results in increased expression of ABCB1 protein]; Ketoconazole inhibits the reaction [Rifampin results in increased expression of ABCB1 mRNA]; Ketoconazole inhibits the reaction [Rifampin results in increased expression of ABCB1 protein]; Ketoconazole inhibits the reaction [Spironolactone results in increased expression of ABCB1 protein]
CTD PMID:10350002, PMID:12235267, PMID:14662772, PMID:15969931, PMID:16819505, PMID:17365992, PMID:18355885, PMID:19070657, PMID:20624464, PMID:21459122, PMID:23707768, PMID:23976943, PMID:25542144, PMID:25844889, PMID:32185415 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 decreases activity
multiple interactions
ISO
EXP
Ketoconazole results in decreased activity of ABCB4 protein
[Chenodeoxycholic Acid co-treated with Ketoconazole] results in increased expression of ABCB4 mRNA
CTD PMID:28437613, PMID:30985903 NCBI chr 4:22,133,984...22,192,687
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 decreases activity
multiple interactions
ISO
EXP
Ketoconazole results in decreased activity of ABCC2 protein
Ketoconazole inhibits the reaction [Spironolactone results in increased expression of ABCC2 mRNA]
CTD PMID:19070657, PMID:19766108 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions EXP Ketoconazole inhibits the reaction [Genistein results in increased expression of ABCG2 mRNA] CTD PMID:32185415 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621
JBrowse link
G Acsm1 acyl-CoA synthetase medium-chain family member 1 decreases expression EXP Ketoconazole results in decreased expression of ACSM1 mRNA CTD PMID:28263823 NCBI chr 1:189,359,374...189,395,277
Ensembl chr 1:189,289,957...189,395,276
JBrowse link
G Adam9 ADAM metallopeptidase domain 9 affects expression EXP Ketoconazole affects the expression of ADAM9 mRNA CTD PMID:25787151 NCBI chr16:71,810,377...71,887,926
Ensembl chr16:71,810,377...71,887,926
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions
increases expression
increases activity
ISO
EXP
AHR promotes the reaction [Ketoconazole results in increased expression of NQO1 mRNA]; AHR promotes the reaction [Ketoconazole results in increased expression of NQO1 protein]; Ketoconazole inhibits the reaction [Phenobarbital results in increased expression of AHR protein]
Ketoconazole results in increased expression of AHR mRNA
Ketoconazole results in increased activity of AHR protein
[Ketoconazole results in increased activity of AHR protein] which results in increased activity of and results in increased localization of NFE2L2 protein; [Ketoconazole results in increased activity of and results in increased localization of AHR protein] which results in increased expression of CYP1A1 mRNA; [Ketoconazole results in increased activity of and results in increased localization of AHR protein] which results in increased expression of CYP1A1 protein; AHR protein promotes the reaction [Ketoconazole inhibits the reaction [TNF protein results in increased abundance of Reactive Oxygen Species]]; AHR protein promotes the reaction [Ketoconazole inhibits the reaction [TNF protein results in increased expression of CXCL8 protein]]; Ketoconazole results in increased activity of and results in increased localization of AHR protein
Ketoconazole inhibits the reaction [Phenobarbital results in increased expression of AHR mRNA]; Ketoconazole inhibits the reaction [Phenobarbital results in increased expression of AHR protein]; Ketoconazole inhibits the reaction [Phenytoin results in increased expression of AHR protein]
CTD PMID:17505019, PMID:17923278, PMID:21753779, PMID:25000292, PMID:31168027 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Ahrr aryl-hydrocarbon receptor repressor multiple interactions
increases expression
EXP [Ketoconazole co-treated with Carbon Tetrachloride] results in increased expression of AHRR mRNA
Ketoconazole results in increased expression of AHRR mRNA
CTD PMID:31168027 NCBI chr 1:31,603,297...31,698,329
Ensembl chr 1:31,603,297...31,698,329
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 affects expression EXP Ketoconazole affects the expression of ALDH1A1 mRNA CTD PMID:18355885 NCBI chr 1:238,222,689...238,264,381
Ensembl chr 1:238,222,521...238,264,330
JBrowse link
G Aldh1a7 aldehyde dehydrogenase family 1, subfamily A7 affects expression EXP Ketoconazole affects the expression of ALDH1A4 mRNA CTD PMID:18355885 NCBI chr 1:240,584,233...240,601,843
Ensembl chr 1:240,562,423...240,601,744
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated multiple interactions ISO Ketoconazole inhibits the reaction [Calcifediol results in increased expression of ALPL mRNA] CTD PMID:21542014 NCBI chr 5:156,086,496...156,141,513
Ensembl chr 5:156,086,497...156,141,537
JBrowse link
G Amh anti-Mullerian hormone increases expression ISO Ketoconazole results in increased expression of AMH protein CTD PMID:16684832 NCBI chr 7:11,775,155...11,777,503
Ensembl chr 7:11,775,155...11,777,503
JBrowse link
G Anxa1 annexin A1 decreases expression EXP Ketoconazole results in decreased expression of ANXA1 mRNA CTD PMID:25787151 NCBI chr 1:237,893,983...237,910,002
Ensembl chr 1:237,893,966...237,910,012
JBrowse link
G Ap1s1 adaptor related protein complex 1 subunit sigma 1 decreases expression ISO Ketoconazole results in decreased expression of AP1S1 mRNA CTD PMID:17175557 NCBI chr12:22,665,128...22,676,079
Ensembl chr12:22,665,112...22,676,075
JBrowse link
G Apoa4 apolipoprotein A4 affects expression EXP Ketoconazole affects the expression of APOA4 mRNA CTD PMID:18355885 NCBI chr 8:50,536,983...50,539,371
Ensembl chr 8:50,537,009...50,539,376
JBrowse link
G Ar androgen receptor multiple interactions
decreases expression
increases activity
decreases activity
ISO
EXP
[Goserelin co-treated with Dutasteride co-treated with bicalutamide co-treated with Ketoconazole] results in decreased expression of AR protein; Ketoconazole inhibits the reaction [Metribolone results in increased activity of AR protein]; Ketoconazole inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]
Ketoconazole inhibits the reaction [Phenytoin results in increased expression of AR protein]
Ketoconazole results in decreased expression of AR protein
Ketoconazole results in increased activity of AR protein
Ketoconazole results in decreased activity of AR protein
CTD PMID:11118046, PMID:18324785, PMID:19226368, PMID:19587329, PMID:24323034, PMID:26867867, PMID:29162470 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) increases expression ISO Ketoconazole results in increased expression of ASNS mRNA CTD PMID:15342952, PMID:17175557 NCBI chr 4:33,742,876...33,761,106
Ensembl chr 4:33,743,364...33,761,163
JBrowse link
G Atf1 activating transcription factor 1 multiple interactions ISO Bucladesine inhibits the reaction [Ketoconazole inhibits the reaction [Dinoprostone results in increased phosphorylation of ATF1 protein]]; Ketoconazole inhibits the reaction [Dinoprostone promotes the reaction [ATF1 protein modified form binds to PTGS2 promoter]]; Ketoconazole inhibits the reaction [Dinoprostone results in increased phosphorylation of ATF1 protein] CTD PMID:12164941 NCBI chr 7:141,882,261...141,924,790
Ensembl chr 7:141,882,251...141,924,788
JBrowse link
G Bad BCL2-associated agonist of cell death increases expression EXP Ketoconazole results in increased expression of BAD mRNA CTD PMID:25787151 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO [Ketoconazole inhibits the reaction [CYP3A4 protein results in increased susceptibility to Amodiaquine]] which results in increased expression of BAX protein; Ketoconazole inhibits the reaction [Calcifediol results in decreased expression of BAX mRNA] CTD PMID:21542014, PMID:31629065 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO [Ketoconazole inhibits the reaction [CYP3A4 protein results in increased susceptibility to Amodiaquine]] which results in decreased expression of BCL2 protein; Ketoconazole inhibits the reaction [Calcifediol results in increased expression of BCL2 mRNA] CTD PMID:21542014, PMID:31629065 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l11 BCL2 like 11 increases expression ISO Ketoconazole results in increased expression of BCL2L11 mRNA CTD PMID:25808816 NCBI chr 3:120,726,906...120,764,192
Ensembl chr 3:120,726,906...120,764,192
JBrowse link
G Bhmt betaine-homocysteine S-methyltransferase affects expression EXP Ketoconazole affects the expression of BHMT mRNA CTD PMID:18355885 NCBI chr 2:23,236,573...23,256,158
Ensembl chr 2:23,236,575...23,256,158
JBrowse link
G Bid BH3 interacting domain death agonist increases expression ISO Ketoconazole results in increased expression of BID mRNA CTD PMID:25808816 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203
JBrowse link
G Bmp2 bone morphogenetic protein 2 multiple interactions ISO Ketoconazole inhibits the reaction [menatetrenone promotes the reaction [Phosphates results in increased expression of BMP2 mRNA]]; Ketoconazole inhibits the reaction [Phosphates promotes the reaction [menatetrenone results in increased expression of BMP2 mRNA]] CTD PMID:31843813 NCBI chr 3:126,335,963...126,346,771
Ensembl chr 3:126,335,863...126,346,318
JBrowse link
G Bnip1 BCL2 interacting protein 1 increases expression ISO Ketoconazole results in increased expression of BNIP1 mRNA CTD PMID:25808816 NCBI chr10:16,677,077...16,689,321
Ensembl chr10:16,677,077...16,689,321
JBrowse link
G Bnip2 BCL2 interacting protein 2 increases expression EXP Ketoconazole results in increased expression of BNIP2 mRNA CTD PMID:25808816 NCBI chr 8:76,400,333...76,426,307
Ensembl chr 8:76,400,341...76,426,503
JBrowse link
G Bnip3 BCL2 interacting protein 3 increases expression EXP Ketoconazole results in increased expression of BNIP3 mRNA CTD PMID:25808816 NCBI chr 1:211,248,098...211,265,282
Ensembl chr 1:211,248,098...211,265,282
JBrowse link
G Casp12 caspase 12 increases expression ISO Ketoconazole results in increased expression of CASP12 mRNA CTD PMID:25808816 NCBI chr 8:2,658,892...2,686,160
Ensembl chr 8:2,659,865...2,686,160
JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions
ISO Ketoconazole results in increased activity of CASP3 protein
Ketoconazole inhibits the reaction [Galactosamine results in increased activity of CASP3 protein]; pyrazolanthrone inhibits the reaction [Ketoconazole results in increased activity of CASP3 protein]
CTD PMID:17936189, PMID:19631732 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp6 caspase 6 decreases expression
increases expression
EXP Ketoconazole results in decreased expression of CASP6 mRNA
Ketoconazole results in increased expression of CASP6 mRNA
CTD PMID:25787151, PMID:25808816 NCBI chr 2:235,341,326...235,353,715
Ensembl chr 2:235,341,365...235,353,967
Ensembl chr 2:235,341,365...235,353,967
JBrowse link
G Casp7 caspase 7 increases expression EXP Ketoconazole results in increased expression of CASP7 mRNA CTD PMID:25808816 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Casp9 caspase 9 increases expression ISO Ketoconazole results in increased expression of CASP9 mRNA CTD PMID:25808816 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase decreases expression EXP Ketoconazole results in decreased expression of CAT mRNA CTD PMID:25787151 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO Dinoprostone deficiency inhibits the reaction [Ketoconazole inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]]; Dinoprostone deficiency inhibits the reaction [Ketoconazole inhibits the reaction [TNF protein results in increased expression of CCL2 protein]]; Ketoconazole inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]; Ketoconazole inhibits the reaction [TNF protein results in increased expression of CCL2 protein]; PTGER2 protein promotes the reaction [Ketoconazole inhibits the reaction [TNF protein results in increased expression of CCL2 protein]]; PTGER3 protein promotes the reaction [Ketoconazole inhibits the reaction [TNF protein results in increased expression of CCL2 protein]] CTD PMID:16784723 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl27 C-C motif chemokine ligand 27 multiple interactions ISO Dinoprostone deficiency inhibits the reaction [Ketoconazole inhibits the reaction [TNF protein results in increased expression of CCL27 mRNA]]; Dinoprostone deficiency inhibits the reaction [Ketoconazole inhibits the reaction [TNF protein results in increased expression of CCL27 protein]]; Ketoconazole inhibits the reaction [TNF protein results in increased expression of CCL27 mRNA]; Ketoconazole inhibits the reaction [TNF protein results in increased expression of CCL27 protein]; PTGER2 protein promotes the reaction [Ketoconazole inhibits the reaction [TNF protein results in increased expression of CCL27 protein]]; PTGER3 protein promotes the reaction [Ketoconazole inhibits the reaction [TNF protein results in increased expression of CCL27 protein]] CTD PMID:16784723 NCBI chr 5:58,159,066...58,166,182
Ensembl chr 5:58,159,066...58,163,584
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions ISO Dinoprostone deficiency inhibits the reaction [Ketoconazole inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA]]; Dinoprostone deficiency inhibits the reaction [Ketoconazole inhibits the reaction [TNF protein results in increased expression of CCL5 protein]]; Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CCL5 mRNA]; Ketoconazole inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA]; Ketoconazole inhibits the reaction [TNF protein results in increased expression of CCL5 protein]; PTGER2 protein promotes the reaction [Ketoconazole inhibits the reaction [TNF protein results in increased expression of CCL5 protein]]; PTGER3 protein promotes the reaction [Ketoconazole inhibits the reaction [TNF protein results in increased expression of CCL5 protein]] CTD PMID:16784723, PMID:23688403 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Ccng1 cyclin G1 increases expression EXP Ketoconazole results in increased expression of CCNG1 mRNA CTD PMID:18289764 NCBI chr10:25,903,925...25,910,298
Ensembl chr10:25,903,911...25,910,325
JBrowse link
G Cd247 Cd247 molecule multiple interactions ISO Ketoconazole inhibits the reaction [[[CD3G protein binds to CD3D protein binds to CD3E protein binds to CD247 protein] which co-treated with CD28 protein] results in increased abundance of Calcitriol]; Ketoconazole inhibits the reaction [Calcifediol promotes the reaction [[[CD3G protein binds to CD3D protein binds to CD3E protein binds to CD247 protein] which co-treated with CD28 protein] results in increased expression of VDR protein]] CTD PMID:24792400 NCBI chr13:83,996,045...84,071,408
Ensembl chr13:83,996,080...84,071,400
JBrowse link
G Cd28 Cd28 molecule multiple interactions ISO Ketoconazole inhibits the reaction [[[CD3G protein binds to CD3D protein binds to CD3E protein binds to CD247 protein] which co-treated with CD28 protein] results in increased abundance of Calcitriol]; Ketoconazole inhibits the reaction [Calcifediol promotes the reaction [[[CD3G protein binds to CD3D protein binds to CD3E protein binds to CD247 protein] which co-treated with CD28 protein] results in increased expression of VDR protein]] CTD PMID:24792400 NCBI chr 9:67,546,408...67,573,858
Ensembl chr 9:67,546,408...67,571,871
JBrowse link
G Cd3d CD3d molecule multiple interactions ISO Ketoconazole inhibits the reaction [[[CD3G protein binds to CD3D protein binds to CD3E protein binds to CD247 protein] which co-treated with CD28 protein] results in increased abundance of Calcitriol]; Ketoconazole inhibits the reaction [Calcifediol promotes the reaction [[[CD3G protein binds to CD3D protein binds to CD3E protein binds to CD247 protein] which co-treated with CD28 protein] results in increased expression of VDR protein]] CTD PMID:24792400 NCBI chr 8:49,282,502...49,287,095
Ensembl chr 8:49,282,460...49,287,110
JBrowse link
G Cd3e CD3e molecule multiple interactions ISO Ketoconazole inhibits the reaction [[[CD3G protein binds to CD3D protein binds to CD3E protein binds to CD247 protein] which co-treated with CD28 protein] results in increased abundance of Calcitriol]; Ketoconazole inhibits the reaction [Calcifediol promotes the reaction [[[CD3G protein binds to CD3D protein binds to CD3E protein binds to CD247 protein] which co-treated with CD28 protein] results in increased expression of VDR protein]] CTD PMID:24792400 NCBI chr 8:49,297,604...49,309,370
Ensembl chr 8:49,297,608...49,308,806
JBrowse link
G Cd3g CD3g molecule multiple interactions ISO Ketoconazole inhibits the reaction [[[CD3G protein binds to CD3D protein binds to CD3E protein binds to CD247 protein] which co-treated with CD28 protein] results in increased abundance of Calcitriol]; Ketoconazole inhibits the reaction [Calcifediol promotes the reaction [[[CD3G protein binds to CD3D protein binds to CD3E protein binds to CD247 protein] which co-treated with CD28 protein] results in increased expression of VDR protein]] CTD PMID:24792400 NCBI chr 8:49,274,553...49,280,943
Ensembl chr 8:49,274,960...49,280,901
JBrowse link
G Cdc42ep3 CDC42 effector protein 3 increases expression EXP Ketoconazole results in increased expression of CDC42EP3 mRNA CTD PMID:28263823 NCBI chr 6:1,922,500...1,942,972
Ensembl chr 6:1,922,500...1,942,972
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO
EXP
Ketoconazole results in increased expression of CDKN1A mRNA CTD PMID:16483768, PMID:25808816 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression EXP Ketoconazole results in increased expression of CDKN1B mRNA CTD PMID:25808816 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Cdkn2c cyclin-dependent kinase inhibitor 2C affects expression EXP Ketoconazole affects the expression of CDKN2C mRNA CTD PMID:18355885 NCBI chr 5:129,347,731...129,352,886
Ensembl chr 5:129,347,732...129,352,886
JBrowse link
G Ces2h carboxylesterase 2H affects expression EXP Ketoconazole affects the expression of CES2 mRNA CTD PMID:18355885 NCBI chr19:37,052,555...37,067,176
Ensembl chr19:37,052,556...37,067,156
JBrowse link
G Cga glycoprotein hormones, alpha polypeptide decreases expression ISO Ketoconazole results in decreased expression of CGA mRNA CTD PMID:25808816 NCBI chr 5:50,362,491...50,393,368
Ensembl chr 5:50,381,244...50,393,367
JBrowse link
G Clmn calmin multiple interactions ISO Ketoconazole promotes the reaction [Calcitriol results in increased expression of CLMN mRNA] CTD PMID:26485663 NCBI chr 6:128,473,592...128,567,267
Ensembl chr 6:128,473,570...128,567,198
JBrowse link
G Clu clusterin affects expression
decreases expression
EXP Ketoconazole affects the expression of CLU mRNA
Ketoconazole results in decreased expression of CLU mRNA
CTD PMID:17558187, PMID:18289764 NCBI chr15:42,626,612...42,665,858
Ensembl chr15:42,640,146...42,665,857
JBrowse link
G Cmtm6 CKLF-like MARVEL transmembrane domain containing 6 affects expression EXP Ketoconazole affects the expression of CMTM6 mRNA CTD PMID:18355885 NCBI chr 8:122,789,208...122,807,560
Ensembl chr 8:122,789,453...122,807,560
JBrowse link
G Cpped1 calcineurin-like phosphoesterase domain containing 1 affects expression EXP Ketoconazole affects the expression of CPPED1 mRNA CTD PMID:18355885 NCBI chr10:3,655,038...3,774,887
Ensembl chr10:3,655,038...3,774,884
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO
EXP
Bucladesine inhibits the reaction [Ketoconazole inhibits the reaction [Dinoprostone results in increased phosphorylation of CREB1 protein]]; Ketoconazole inhibits the reaction [Dinoprostone promotes the reaction [CREB1 protein modified form binds to PTGS2 promoter]]; Ketoconazole inhibits the reaction [Dinoprostone results in increased phosphorylation of CREB1 protein]
Ketoconazole inhibits the reaction [Arachidonic Acid results in increased phosphorylation of CREB1 protein]; Ketoconazole inhibits the reaction [Epinephrine results in increased phosphorylation of CREB1 protein]
CTD PMID:12164941, PMID:17680988 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Crem cAMP responsive element modulator affects expression EXP Ketoconazole affects the expression of CREM mRNA CTD PMID:18355885 NCBI chr17:57,021,704...57,090,888
Ensembl chr17:57,031,766...57,090,888
JBrowse link
G Ctss cathepsin S affects expression EXP Ketoconazole affects the expression of CTSS mRNA CTD PMID:18289764 NCBI chr 2:197,655,780...197,679,768
Ensembl chr 2:197,655,786...197,679,458
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 multiple interactions ISO Ketoconazole inhibits the reaction [Biological Products results in increased expression of CXCL10 mRNA]; Ketoconazole inhibits the reaction [Biological Products results in increased expression of CXCL10 protein] CTD PMID:24471457 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
JBrowse link
G Cycs cytochrome c, somatic decreases expression EXP Ketoconazole results in decreased expression of CYCS mRNA CTD PMID:25787151 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
JBrowse link
G Cyct cytochrome c, testis increases expression EXP Ketoconazole results in increased expression of CYCT mRNA CTD PMID:25787151 NCBI chr 3:63,204,779...63,211,847
Ensembl chr 3:62,818,502...63,211,845
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 increases expression EXP Ketoconazole results in increased expression of CYP11A1 mRNA CTD PMID:26610754 NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893
JBrowse link
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 decreases activity ISO Ketoconazole results in decreased activity of CYP11B1 protein CTD PMID:15743198 NCBI chr 7:116,248,759...116,255,205
Ensembl chr 7:116,156,219...116,255,167
JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 decreases activity
multiple interactions
increases expression
ISO Ketoconazole results in decreased activity of CYP11B2 protein
Ketoconazole promotes the reaction [Colforsin results in increased expression of CYP11B2 mRNA]
Ketoconazole results in increased expression of CYP11B2 mRNA
CTD PMID:15743198, PMID:16935330 NCBI chr 7:116,155,928...116,161,781
Ensembl chr 7:116,156,219...116,255,167
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases activity
decreases expression
multiple interactions
ISO
EXP
Ketoconazole results in decreased activity of CYP17A1 protein
Ketoconazole results in decreased expression of CYP17A1 mRNA
Ketoconazole inhibits the reaction [Colforsin results in increased expression of CYP17A1 mRNA]
CTD PMID:11118046, PMID:15743198, PMID:15771425, PMID:15934942, PMID:16935330, PMID:25993309, PMID:31330226 NCBI chr 1:266,422,127...266,429,947
Ensembl chr 1:266,422,132...266,428,239
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 increases activity
multiple interactions
decreases activity
ISO Ketoconazole results in increased activity of CYP19A1 protein
[Ketoconazole results in increased activity of CYP19A1 protein] which results in increased chemical synthesis of Estrone; [Ketoconazole results in increased activity of CYP19A1 protein] which results in increased metabolism of Androstenedione
Ketoconazole results in decreased activity of CYP19A1 protein
CTD PMID:20087668, PMID:27159630, PMID:31330226 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases activity
increases expression
multiple interactions
decreases activity
ISO
EXP
Ketoconazole results in increased activity of CYP1A1 protein
Ketoconazole results in increased expression of CYP1A1 mRNA
Ketoconazole binds to and results in decreased activity of and results in increased expression of CYP1A1 protein; Ketoconazole results in increased expression of and results in increased activity of CYP1A1 protein
Ketoconazole results in increased expression of CYP1A1 mRNA; Ketoconazole results in increased expression of CYP1A1 protein
Ketoconazole results in decreased activity of CYP1A1 protein
[Ketoconazole results in increased activity of and results in increased localization of AHR protein] which results in increased expression of CYP1A1 mRNA; [Ketoconazole results in increased activity of and results in increased localization of AHR protein] which results in increased expression of CYP1A1 protein; Dactinomycin inhibits the reaction [Ketoconazole results in increased expression of CYP1A1 mRNA]; Ketoconazole binds to and results in decreased activity of and results in increased expression of CYP1A1 protein; Ketoconazole inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; Ketoconazole results in increased expression of and results in increased activity of CYP1A1 protein
[Ketoconazole co-treated with Carbon Tetrachloride] results in increased expression of CYP1A1 mRNA; Ketoconazole inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]
CTD PMID:14709627, PMID:17283379, PMID:18420780, PMID:18493746, PMID:19070657, PMID:21753779, PMID:25000292, PMID:26886340, PMID:31168027 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
increases expression
decreases activity
ISO
EXP
Ketoconazole affects the reaction [[NADP co-treated with CYP1A2 protein co-treated with CYP2C8 protein co-treated with CYP2C9 protein co-treated with CYP2C19 protein co-treated with CYP2D6 protein co-treated with CYP3A4 protein co-treated with POR protein] results in increased metabolism of 1-(3-(4-phenoxyphenoxy)-2-oxopropyl)indole-5-carboxylic acid]; Ketoconazole inhibits the reaction [CYP1A2 protein results in increased metabolism of Triazines]
Ketoconazole results in increased expression of CYP1A2 mRNA; Ketoconazole results in increased expression of CYP1A2 protein
Ketoconazole results in decreased activity of CYP1A2 protein
Ketoconazole inhibits the reaction [CYP1A2 protein results in increased metabolism of 3-cyano-7-ethoxycoumarin]
Ketoconazole inhibits the reaction [CYP1A2 protein results in increased oxidation of Uroporphyrinogens]
CTD PMID:1567206, PMID:9305587, PMID:12814958, PMID:15618748, PMID:15879494, PMID:15916432, PMID:18420780, PMID:19858067, PMID:24120545, PMID:25000292 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity ISO Ketoconazole results in decreased activity of CYP1B1 protein CTD PMID:14709627, PMID:18420780 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 multiple interactions
decreases activity
EXP
ISO
[Ketoconazole co-treated with Calcitriol] results in increased expression of CYP24A1 mRNA; Ketoconazole inhibits the reaction [Calcitriol results in increased activity of CYP24A1 protein]
Ketoconazole inhibits the reaction [Calcifediol results in increased expression of CYP24A1 mRNA]; Ketoconazole promotes the reaction [Calcitriol results in increased expression of CYP24A1 mRNA]
[Ketoconazole results in decreased metabolism of alfacalcidol] which results in decreased expression of CYP24A1 mRNA; [Ketoconazole results in decreased metabolism of Calcitriol] which results in increased expression of CYP24A1 mRNA; Ketoconazole promotes the reaction [Calcitriol results in increased expression of CYP24A1 mRNA]
Ketoconazole results in decreased activity of CYP24A1 protein
CTD PMID:16483768, PMID:16824767, PMID:18840526, PMID:20206692, PMID:26485663 NCBI chr 3:168,097,484...168,111,920
Ensembl chr 3:168,097,485...168,111,920
JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 decreases response to substance
increases expression
decreases activity
multiple interactions
ISO
EXP
Ketoconazole results in decreased susceptibility to CYP26A1 protein
Ketoconazole results in increased expression of CYP26A1 mRNA
Ketoconazole results in decreased activity of CYP26A1; Ketoconazole results in decreased activity of CYP26A1 protein
[[Ketoconazole results in decreased activity of CYP26A1 protein] which results in decreased metabolism of Tretinoin] which results in decreased chemical synthesis of 4-hydroxyretinoic acid; [[Ketoconazole results in decreased activity of CYP26A1 protein] which results in decreased metabolism of Tretinoin] which results in decreased chemical synthesis of 4-oxoretinoic acid; [Ketoconazole results in decreased activity of CYP26A1 protein] which results in decreased chemical synthesis of 4-hydroxyretinoic acid; [Ketoconazole results in decreased activity of CYP26A1 protein] which results in decreased chemical synthesis of 4-oxoretinoic acid; [Ketoconazole results in decreased activity of CYP26A1 protein] which results in decreased metabolism of Tretinoin; Ketoconazole inhibits the reaction [CYP26A1 mRNA results in increased chemical synthesis of 4-hydroxyretinoic acid]; Ketoconazole inhibits the reaction [CYP26A1 mRNA results in increased chemical synthesis of 4-oxoretinoic acid]; Ketoconazole inhibits the reaction [CYP26A1 mRNA results in increased metabolism of 4-oxoretinoic acid]; Ketoconazole inhibits the reaction [CYP26A1 mRNA results in increased metabolism of Tretinoin]; Ketoconazole inhibits the reaction [CYP26A1 protein inhibits the reaction [Tretinoin results in increased activity of FAS protein]]; Ketoconazole inhibits the reaction [CYP26A1 protein inhibits the reaction [Tretinoin results in increased activity of TNF protein]]; Ketoconazole inhibits the reaction [CYP26A1 protein inhibits the reaction [Tretinoin results in increased activity of TNFSF10 protein]]; Ketoconazole inhibits the reaction [CYP26A1 protein results in increased metabolism of and results in decreased susceptibility to Tretinoin]; Ketoconazole inhibits the reaction [CYP26A1 protein results in increased metabolism of Tretinoin]; Ketoconazole inhibits the reaction [CYP26A1 results in increased metabolism of Tretinoin]
CTD PMID:12091498, PMID:14532297, PMID:15703382, PMID:18059332, PMID:21906690, PMID:25492813, PMID:28263823 NCBI chr 1:256,382,861...256,386,729
Ensembl chr 1:256,382,791...256,386,729
JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 multiple interactions
decreases activity
ISO Ketoconazole inhibits the reaction [CYP26B1 protein results in increased metabolism of Tretinoin]; Ketoconazole inhibits the reaction [CYP26B1 results in increased metabolism of Tretinoin]
Ketoconazole results in decreased activity of CYP26B1
CTD PMID:14532297, PMID:21906690 NCBI chr 4:116,261,796...116,278,615
Ensembl chr 4:116,261,796...116,278,615
JBrowse link
G Cyp26c1 cytochrome P450, family 26, subfamily C, polypeptide 1 multiple interactions ISO Ketoconazole inhibits the reaction [CYP26C1 protein results in increased metabolism of alitretinoin]; Ketoconazole inhibits the reaction [CYP26C1 protein results in increased metabolism of Tretinoin] CTD PMID:21906690 NCBI chr 1:256,369,410...256,380,649
Ensembl chr 1:256,370,850...256,378,335
JBrowse link
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 decreases activity EXP Ketoconazole results in decreased activity of CYP27B1 protein CTD PMID:16483768 NCBI chr 7:70,333,150...70,340,006
Ensembl chr 7:70,335,061...70,340,005
JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 affects expression
decreases activity
increases expression
EXP Ketoconazole affects the expression of CYP2A1 mRNA
Ketoconazole results in decreased activity of CYP2A1 protein
Ketoconazole results in increased expression of CYP2A1 protein
CTD PMID:7986207, PMID:15879494, PMID:18355885 NCBI chr 1:83,711,223...83,725,222
Ensembl chr 1:83,653,234...83,766,484
JBrowse link
G Cyp2a2 cytochrome P450, family 2, subfamily a, polypeptide 2 multiple interactions EXP Ketoconazole inhibits the reaction [CYP2A2 protein results in increased metabolism of 7-benzyloxyquinoline] CTD PMID:19858067 NCBI chr 1:83,744,229...83,766,490
Ensembl chr 1:83,653,234...83,766,484
JBrowse link
G Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 increases expression ISO Ketoconazole results in increased expression of CYP2A5 mRNA; Ketoconazole results in increased expression of CYP2A5 protein CTD PMID:17966066 NCBI chr 1:83,653,248...83,662,118
Ensembl chr 1:83,653,234...83,766,484
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 multiple interactions
increases expression
decreases activity
EXP
ISO
Ketoconazole inhibits the reaction [CYP2B1 protein results in increased metabolism of 7-benzyloxy-4-trifluoromethylcoumarin]
Ketoconazole results in increased expression of CYP2B10 mRNA
Ketoconazole results in decreased activity of CYP2B10 protein
CTD PMID:17966066, PMID:18420780, PMID:19858067 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2b15 cytochrome P450, family 2, subfamily b, polypeptide 15 affects expression EXP Ketoconazole affects the expression of CYP2B15 mRNA CTD PMID:18355885 NCBI chr 1:251,325,923...251,338,404
Ensembl chr 1:251,325,923...251,338,358
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 decreases activity
multiple interactions
ISO Ketoconazole results in decreased activity of CYP2B6 protein
Ketoconazole inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP2B6 mRNA]; Ketoconazole inhibits the reaction [Phenobarbital results in increased expression of CYP2B6 mRNA]; Ketoconazole inhibits the reaction [Rifampin results in increased expression of CYP2B6 mRNA]
CTD PMID:14709627, PMID:16608920, PMID:17438109 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 multiple interactions
decreases activity
EXP Ketoconazole inhibits the reaction [CYP2C11 protein results in increased metabolism of 7-methoxy-4-trifluoromethylcoumarin]
Ketoconazole results in decreased activity of CYP2C11 protein
CTD PMID:15879494, PMID:19858067 NCBI chr 1:257,676,172...258,004,428
Ensembl chr 1:257,970,345...258,004,434
JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 multiple interactions
decreases activity
EXP
ISO
Ketoconazole inhibits the reaction [CYP2C6V1 protein results in increased metabolism of 7-methoxy-4-trifluoromethylcoumarin]
Ketoconazole affects the reaction [[NADP co-treated with CYP1A2 protein co-treated with CYP2C8 protein co-treated with CYP2C9 protein co-treated with CYP2C19 protein co-treated with CYP2D6 protein co-treated with CYP3A4 protein co-treated with POR protein] results in increased metabolism of 1-(3-(4-phenoxyphenoxy)-2-oxopropyl)indole-5-carboxylic acid]
Ketoconazole results in decreased activity of CYP2C19 protein
Ketoconazole results in decreased activity of CYP2C6V1 protein
CTD PMID:12814958, PMID:14709627, PMID:15618748, PMID:15879494, PMID:19858067, PMID:24120545 NCBI chr 1:147,713,879...147,814,410
Ensembl chr 1:147,713,892...147,888,007
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 decreases activity
multiple interactions
ISO Ketoconazole results in decreased activity of CYP2C8 protein
Ketoconazole results in decreased activity of CYP2C29 protein
Ketoconazole affects the reaction [[NADP co-treated with CYP1A2 protein co-treated with CYP2C8 protein co-treated with CYP2C9 protein co-treated with CYP2C19 protein co-treated with CYP2D6 protein co-treated with CYP3A4 protein co-treated with POR protein] results in increased metabolism of 1-(3-(4-phenoxyphenoxy)-2-oxopropyl)indole-5-carboxylic acid]
CTD PMID:14709627, PMID:15601807, PMID:18420780, PMID:24120545 NCBI chr 1:147,236,480...147,307,988 JBrowse link
G Cyp2d2 cytochrome P450, family 2, subfamily d, polypeptide 2 multiple interactions EXP Ketoconazole inhibits the reaction [CYP2D2 protein results in increased metabolism of 3-(2-(N,N-diethyl-N-methylammonium)ethyl)-7-methoxy-4-methylcoumarin] CTD PMID:19858067 NCBI chr 7:123,651,827...123,655,896
Ensembl chr 7:123,651,827...123,655,896
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 multiple interactions
decreases expression
decreases activity
ISO Ketoconazole affects the reaction [[NADP co-treated with CYP1A2 protein co-treated with CYP2C8 protein co-treated with CYP2C9 protein co-treated with CYP2C19 protein co-treated with CYP2D6 protein co-treated with CYP3A4 protein co-treated with POR protein] results in increased metabolism of 1-(3-(4-phenoxyphenoxy)-2-oxopropyl)indole-5-carboxylic acid]; Ketoconazole inhibits the reaction [CYP2D6 protein results in increased metabolism of YM 758]
Ketoconazole results in decreased expression of CYP2D22 mRNA; Ketoconazole results in decreased expression of CYP2D22 protein
Ketoconazole results in decreased activity of CYP2D22 protein; Ketoconazole results in decreased activity of CYP2D6 protein
Ketoconazole inhibits the reaction [CYP2D22 protein results in increased metabolism of Dextromethorphan]; Ketoconazole inhibits the reaction [Maneb results in decreased expression of CYP2D22 protein]; Ketoconazole inhibits the reaction [Nicotine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of CYP2D22 mRNA]]; Ketoconazole inhibits the reaction [Nicotine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of CYP2D22 protein]]; Ketoconazole inhibits the reaction [Nicotine results in increased expression of CYP2D22 mRNA]; Ketoconazole inhibits the reaction [Nicotine results in increased expression of CYP2D22 protein]; Ketoconazole inhibits the reaction [Paraquat results in decreased expression of CYP2D22 protein]; Ketoconazole promotes the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of CYP2D22 mRNA]; Ketoconazole promotes the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of CYP2D22 protein]; Nicotine inhibits the reaction [Ketoconazole results in decreased expression of CYP2D22 mRNA]; Nicotine inhibits the reaction [Ketoconazole results in decreased expression of CYP2D22 protein]
CTD PMID:15618748, PMID:16595712, PMID:18420780, PMID:19230594, PMID:19594327, PMID:22334051, PMID:24120545 NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases activity ISO Ketoconazole results in decreased activity of CYP2E1 protein CTD PMID:15618748 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 decreases activity ISO Ketoconazole results in decreased activity of CYP2J2 protein CTD PMID:12851038 NCBI chr 5:119,546,458...119,564,843
Ensembl chr 5:119,546,461...119,564,846
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions
decreases activity
EXP Ketoconazole inhibits the reaction [CYP3A2 protein results in increased metabolism of 7-benzyloxyquinoline]; Ketoconazole inhibits the reaction [Phenytoin results in increased expression of CYP3A2 protein]
Ketoconazole results in decreased activity of CYP3A2 protein; Ketoconazole results in decreased activity of CYP3A4 protein
CTD PMID:12814958, PMID:15879494, PMID:19226368, PMID:19858067, PMID:31870919 NCBI chr12:11,641,500...11,677,818
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 multiple interactions
decreases activity
affects expression
EXP Ketoconazole inhibits the reaction [CYP3A23-3A1 protein results in increased metabolism of 7-benzyloxyquinoline]; Ketoconazole inhibits the reaction [Genistein results in increased expression of CYP3A23-3A1 mRNA]
Ketoconazole results in decreased activity of CYP3A23-3A1 protein
Ketoconazole affects the expression of CYP3A23-3A1 mRNA
CTD PMID:12814958, PMID:15879494, PMID:18355885, PMID:19858067, PMID:32185415 NCBI chr12:11,053,888...11,082,742
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 multiple interactions
affects response to substance
decreases activity
ISO CYP3A5 gene polymorphism affects the reaction [Ketoconazole results in decreased metabolism of Tacrolimus]; Ketoconazole inhibits the reaction [Beclomethasone results in increased expression of CYP3A5 mRNA]; Ketoconazole inhibits the reaction [Budesonide results in increased expression of CYP3A5 mRNA]; Ketoconazole inhibits the reaction [CYP3A5 protein affects the metabolism of Alfentanil]; Ketoconazole inhibits the reaction [CYP3A5 protein results in increased hydroxylation of Testosterone]; Ketoconazole inhibits the reaction [CYP3A5 protein results in increased oxidation of Lithocholic Acid]; Ketoconazole inhibits the reaction [flunisolide results in increased expression of CYP3A5 mRNA]; Ketoconazole inhibits the reaction [Fluticasone results in increased expression of CYP3A5 mRNA]; Ketoconazole inhibits the reaction [Triamcinolone Acetonide results in increased expression of CYP3A5 mRNA]
CYP3A5 gene polymorphism affects the susceptibility to Ketoconazole
Ketoconazole results in decreased activity of CYP3A5 protein
CTD PMID:15557344, PMID:15731592, PMID:19384264, PMID:24555085, PMID:26302866, PMID:31102695 NCBI chr12:19,074,288...19,114,491
Ensembl chr12:19,074,583...19,114,399
JBrowse link
G Cyp4f1 cytochrome P450, family 4, subfamily f, polypeptide 1 decreases activity
affects expression
ISO
EXP
Ketoconazole results in decreased activity of CYP4F12 protein
Ketoconazole affects the expression of CYP4F2 mRNA
CTD PMID:14709627, PMID:18355885 NCBI chr 7:15,179,472...15,191,113
Ensembl chr 7:15,179,467...15,190,796
JBrowse link
G Cyp51 cytochrome P450, family 51 decreases activity
increases expression
decreases response to substance
multiple interactions
increases activity
ISO
EXP
Ketoconazole results in decreased activity of CYP51A1 protein
Ketoconazole results in increased expression of CYP51 mRNA
CYP51A1 gene results in decreased susceptibility to Ketoconazole
[Ketoconazole results in increased activity of CYP51 protein] which results in increased abundance of Lanosterol
CYP51A1 gene inhibits the reaction [Ketoconazole results in decreased chemical synthesis of Ergosterol]; CYP51A1 gene inhibits the reaction [Ketoconazole results in decreased metabolism of and results in increased abundance of 14-methylergosta-8,24(28)-dien-3,6-diol]; CYP51A1 gene inhibits the reaction [Ketoconazole results in decreased metabolism of and results in increased abundance of Lanosterol]
Ketoconazole results in increased expression of CYP51 mRNA; Ketoconazole results in increased expression of CYP51 protein
CTD PMID:12617470, PMID:16989930, PMID:17966066, PMID:18694951, PMID:28263823, PMID:29337257 NCBI chr 4:27,175,564...27,194,018
Ensembl chr 4:27,175,243...27,194,018
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 multiple interactions EXP [Chenodeoxycholic Acid co-treated with Ketoconazole] results in decreased expression of CYP7A1 mRNA CTD PMID:30985903 NCBI chr 5:19,358,734...19,368,431
Ensembl chr 5:19,358,734...19,368,431
JBrowse link
G Dcaf8 DDB1 and CUL4 associated factor 8 affects expression EXP Ketoconazole affects the expression of DCAF8 mRNA CTD PMID:18355885 NCBI chr13:90,532,153...90,587,542
Ensembl chr13:90,532,326...90,591,796
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
multiple interactions
ISO Ketoconazole results in increased expression of DDIT3 mRNA
EIF2S1 protein mutant form inhibits the reaction [Ketoconazole results in increased expression of DDIT3 mRNA]
CTD PMID:16330322 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Depp1 DEPP1, autophagy regulator decreases expression
increases expression
ISO Ketoconazole results in decreased expression of DEPP1 mRNA
Ketoconazole results in increased expression of DEPP1 mRNA
CTD PMID:15342952, PMID:17175557 NCBI chr 4:148,780,330...148,784,566
Ensembl chr 4:148,782,479...148,784,562
JBrowse link
G Dhcr7 7-dehydrocholesterol reductase increases expression EXP Ketoconazole results in increased expression of DHCR7 mRNA CTD PMID:28263823 NCBI chr 1:217,018,916...217,034,890
Ensembl chr 1:217,018,916...217,034,904
JBrowse link
G Dmc1 DNA meiotic recombinase 1 increases expression ISO Ketoconazole results in increased expression of DMC1 mRNA CTD PMID:16574651 NCBI chr 7:120,796,217...120,840,524
Ensembl chr 7:120,796,217...120,839,577
JBrowse link
G Drd4 dopamine receptor D4 decreases expression
multiple interactions
ISO Ketoconazole results in decreased expression of DRD4 mRNA
Ketoconazole inhibits the reaction [FSHB protein results in increased expression of DRD4 mRNA]; Metribolone inhibits the reaction [Ketoconazole results in decreased expression of DRD4 mRNA]
CTD PMID:19587329 NCBI chr 1:214,278,296...214,282,818
Ensembl chr 1:214,278,296...214,281,483
JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression EXP Ketoconazole results in increased expression of DUSP1 mRNA CTD PMID:25787151 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418
JBrowse link
G Egf epidermal growth factor increases uptake
multiple interactions
ISO Ketoconazole results in increased uptake of EGF protein
Ketoconazole inhibits the reaction [EGF protein results in increased uptake of and results in increased degradation of EGFR protein]
CTD PMID:23125191 NCBI chr 2:68,820,616...68,895,537 JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO Ketoconazole inhibits the reaction [EGF protein results in increased uptake of and results in increased degradation of EGFR protein] CTD PMID:23125191 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions ISO Ketoconazole inhibits the reaction [Tunicamycin results in increased phosphorylation of EIF2AK3 protein] CTD PMID:16330322 NCBI chr 4:98,648,513...98,709,695
Ensembl chr 4:98,648,545...98,709,694
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha multiple interactions ISO EIF2S1 protein mutant form inhibits the reaction [Ketoconazole results in increased expression of DDIT3 mRNA]; EIF2S1 protein mutant form promotes the reaction [Ketoconazole results in increased expression of IDI1 mRNA]; EIF2S1 protein mutant form promotes the reaction [Ketoconazole results in increased expression of MSMO1 mRNA] CTD PMID:16330322 NCBI chr 6:102,048,372...102,073,041
Ensembl chr 6:102,048,372...102,073,041
JBrowse link
G Eif4b eukaryotic translation initiation factor 4B affects expression EXP Ketoconazole affects the expression of EIF4B mRNA CTD PMID:18355885 NCBI chr 7:143,679,656...143,701,452
Ensembl chr 7:143,679,617...143,701,452
JBrowse link
G Ephx1 epoxide hydrolase 1 affects expression EXP Ketoconazole affects the expression of EPHX1 mRNA CTD PMID:18355885 NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579
JBrowse link
G Epo erythropoietin multiple interactions ISO Ketoconazole inhibits the reaction [CYP3A4 protein promotes the reaction [Oxygen deficiency results in increased expression of EPO mRNA]]; Ketoconazole inhibits the reaction [Oxygen deficiency results in increased expression of EPO mRNA] CTD PMID:21566342 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266
JBrowse link
G Eppin epididymal peptidase inhibitor multiple interactions
decreases expression
ISO Ketoconazole inhibits the reaction [FSHB protein results in increased expression of EPPIN mRNA]; Metribolone inhibits the reaction [Ketoconazole results in decreased expression of EPPIN mRNA] CTD PMID:19587329 NCBI chr 3:161,043,761...161,050,550
Ensembl chr 3:161,041,727...161,050,557
JBrowse link
G Erp29 endoplasmic reticulum protein 29 affects expression EXP Ketoconazole affects the expression of ERP29 mRNA CTD PMID:18355885 NCBI chr12:40,619,377...40,625,884
Ensembl chr12:40,619,377...40,625,883
JBrowse link
G F3 coagulation factor III, tissue factor increases expression ISO Ketoconazole results in increased expression of F3 protein CTD PMID:25569083 NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272
JBrowse link
G Fabp1 fatty acid binding protein 1 increases expression ISO Ketoconazole results in increased expression of FABP1 mRNA CTD PMID:15342952, PMID:17175557, PMID:17567588 NCBI chr 4:99,063,181...99,066,957
Ensembl chr 4:99,063,181...99,066,954
JBrowse link
G Faf1 Fas associated factor 1 increases expression ISO
EXP
Ketoconazole results in increased expression of FAF1 mRNA CTD PMID:25808816 NCBI chr 5:129,370,767...129,738,393
Ensembl chr 5:129,448,879...129,738,252
JBrowse link
G Fas Fas cell surface death receptor increases expression
multiple interactions
ISO
EXP
Ketoconazole results in increased expression of FAS mRNA
Ketoconazole inhibits the reaction [CYP26A1 protein inhibits the reaction [Tretinoin results in increased activity of FAS protein]]
CTD PMID:15703382, PMID:25808816 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 increases expression EXP Ketoconazole results in increased expression of FDFT1 mRNA CTD PMID:28263823 NCBI chr15:46,339,248...46,367,302
Ensembl chr15:46,339,249...46,367,302
JBrowse link
G Fgfbp3 fibroblast growth factor binding protein 3 increases expression EXP Ketoconazole results in increased expression of FGFBP3 mRNA CTD PMID:28263823 NCBI chr 1:255,555,050...255,557,055
Ensembl chr 1:255,555,050...255,557,055
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit decreases expression EXP Ketoconazole results in decreased expression of FOSL1 mRNA CTD PMID:25787151 NCBI chr 1:220,826,560...220,835,066
Ensembl chr 1:220,826,560...220,835,066
JBrowse link
G Fshb follicle stimulating hormone subunit beta multiple interactions ISO Ketoconazole inhibits the reaction [FSHB protein results in increased expression of DRD4 mRNA]; Ketoconazole inhibits the reaction [FSHB protein results in increased expression of EPPIN mRNA]; Ketoconazole inhibits the reaction [FSHB protein results in increased expression of GPD1 mRNA]; Ketoconazole inhibits the reaction [FSHB protein results in increased expression of RHOX5 mRNA] CTD PMID:19587329 NCBI chr 3:98,088,321...98,092,131
Ensembl chr 3:98,088,324...98,092,131
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 affects expression EXP Ketoconazole affects the expression of G6PC mRNA CTD PMID:18289764 NCBI chr10:89,286,009...89,296,213
Ensembl chr10:89,285,855...89,296,213
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase increases expression ISO Ketoconazole results in increased expression of G6PD mRNA CTD PMID:25399406 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression EXP Ketoconazole results in increased expression of GADD45A mRNA CTD PMID:16483768 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Gckr glucokinase regulator affects expression EXP Ketoconazole affects the expression of GCKR mRNA CTD PMID:18355885 NCBI chr 6:26,355,296...26,385,761
Ensembl chr 6:26,355,296...26,385,761
JBrowse link
G Gdpd3 glycerophosphodiester phosphodiesterase domain containing 3 increases expression ISO Ketoconazole results in increased expression of GDPD3 mRNA CTD PMID:15342952, PMID:17175557 NCBI chr 1:198,199,032...198,209,178
Ensembl chr 1:198,199,622...198,209,150
JBrowse link
G Gls2 glutaminase 2 affects expression EXP Ketoconazole affects the expression of GLS2 mRNA CTD PMID:18355885 NCBI chr 7:2,605,679...2,621,853
Ensembl chr 7:2,605,719...2,621,852
JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 affects expression EXP Ketoconazole affects the expression of GOT2 mRNA CTD PMID:18355885 NCBI chr19:9,587,637...9,613,323
Ensembl chr19:9,587,653...9,613,340
JBrowse link
G Gpd1 glycerol-3-phosphate dehydrogenase 1 multiple interactions
decreases expression
ISO Ketoconazole inhibits the reaction [FSHB protein results in increased expression of GPD1 mRNA]; Metribolone inhibits the reaction [Ketoconazole results in decreased expression of GPD1 mRNA] CTD PMID:19587329 NCBI chr 7:141,368,928...141,377,931
Ensembl chr 7:141,370,491...141,377,928
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP
ISO
Ketoconazole inhibits the reaction [Carbon Tetrachloride results in increased activity of GPT protein]
Ketoconazole inhibits the reaction [columbin results in increased activity of GPT protein]
CTD PMID:31168027, PMID:32162908 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Gpx4 glutathione peroxidase 4 increases expression EXP Ketoconazole results in increased expression of GPX4 mRNA CTD PMID:17679765 NCBI chr 7:12,516,357...12,519,154
Ensembl chr 7:12,516,352...12,519,154
JBrowse link
G Grb14 growth factor receptor bound protein 14 affects expression EXP Ketoconazole affects the expression of GRB14 mRNA CTD PMID:18355885 NCBI chr 3:50,937,403...51,054,447
Ensembl chr 3:50,937,669...51,054,378
JBrowse link
G Gsr glutathione-disulfide reductase increases expression
multiple interactions
EXP Ketoconazole results in increased expression of GSR mRNA
[Ketoconazole co-treated with Carbon Tetrachloride] results in increased expression of GSR mRNA
CTD PMID:31168027 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 multiple interactions
decreases expression
ISO
EXP
Ketoconazole inhibits the reaction [Phenobarbital results in increased expression of GSTA1 mRNA]; Ketoconazole inhibits the reaction [Rifampin results in increased expression of GSTA1 mRNA]
Ketoconazole inhibits the reaction [Carbon Tetrachloride results in decreased expression of GSTA1 mRNA]; Ketoconazole inhibits the reaction [Genistein results in increased expression of GSTA1 mRNA]
Ketoconazole results in decreased expression of GSTA1 mRNA
CTD PMID:16608920, PMID:31168027, PMID:32185415 NCBI chr 9:27,366,404...27,381,004
Ensembl chr 9:27,368,272...27,452,902
JBrowse link
G Gsta2 glutathione S-transferase alpha 2 decreases expression ISO Ketoconazole results in decreased expression of GSTA2 mRNA CTD PMID:16608920 NCBI chr 8:85,640,081...85,645,621 JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases expression ISO Ketoconazole results in increased expression of GSTM1 protein CTD PMID:17966066 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gstm2 glutathione S-transferase mu 2 affects expression EXP Ketoconazole affects the expression of GSTM2 mRNA CTD PMID:18289764 NCBI chr 2:210,778,041...210,782,807
Ensembl chr 2:210,720,704...210,782,856
JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO Ketoconazole inhibits the reaction [[CYP3A4 protein co-treated with GSTP1 protein co-treated with Glutathione] results in increased abundance of 2'-(glutathion-S-yl)-deschlorodiclofenac]; Ketoconazole inhibits the reaction [[CYP3A4 protein co-treated with GSTP1 protein co-treated with Glutathione] results in increased abundance of 5-hydroxydiclofenac] CTD PMID:24246759 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Hal histidine ammonia lyase affects expression EXP Ketoconazole affects the expression of HAL mRNA CTD PMID:18355885 NCBI chr 7:34,326,087...34,356,413
Ensembl chr 7:34,326,087...34,356,413
JBrowse link
G Hamp hepcidin antimicrobial peptide multiple interactions
decreases expression
ISO Ketoconazole inhibits the reaction [IL6 protein results in increased expression of HAMP mRNA]
Ketoconazole results in decreased expression of HAMP protein
CTD PMID:17966066 NCBI chr 1:89,368,021...89,369,960
Ensembl chr 1:89,368,021...89,369,960
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 decreases expression EXP Ketoconazole results in decreased expression of HAVCR1 mRNA CTD PMID:18289764 NCBI chr10:31,813,819...31,860,934
Ensembl chr10:31,813,814...31,848,379
JBrowse link
G Hmgb2 high mobility group box 2 affects expression EXP Ketoconazole affects the expression of HMGB2 mRNA CTD PMID:18355885 NCBI chr16:36,077,615...36,080,191
Ensembl chr16:36,077,617...36,080,191
Ensembl chr11:36,077,617...36,080,191
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase increases activity
increases expression
decreases expression
decreases activity
multiple interactions
EXP
ISO
Ketoconazole results in increased activity of HMGCR protein
Ketoconazole results in increased expression of HMGCR mRNA
Ketoconazole results in decreased expression of HMGCR mRNA
Ketoconazole results in decreased activity of HMGCR protein
[Colforsin co-treated with Ketoconazole] results in decreased expression of HMGCR mRNA
CTD PMID:9199277, PMID:12617470, PMID:16935330, PMID:28263823 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 increases expression EXP Ketoconazole results in increased expression of HMGCS1 mRNA CTD PMID:28263823 NCBI chr 2:52,427,351...52,445,082
Ensembl chr 2:52,431,601...52,445,055
JBrowse link
G Hmox1 heme oxygenase 1 affects expression
multiple interactions
EXP
ISO
Ketoconazole affects the expression of HMOX1 mRNA
[Ketoconazole co-treated with Carbon Tetrachloride] results in increased expression of HMOX1 protein; Ketoconazole inhibits the reaction [Diclofenac results in increased expression of HMOX1 mRNA]
Ketoconazole inhibits the reaction [Cadmium Chloride results in increased expression of HMOX1 protein]
CTD PMID:12763371, PMID:18289764, PMID:22659318, PMID:31168027 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hpn hepsin increases expression ISO Ketoconazole results in increased expression of HPN mRNA CTD PMID:15342952 NCBI chr 1:89,534,112...89,549,575
Ensembl chr 1:89,534,106...89,543,967
JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 decreases activity ISO Ketoconazole results in decreased activity of HSD11B2 protein CTD PMID:10664531 NCBI chr19:37,476,083...37,481,326
Ensembl chr19:37,476,095...37,481,307
JBrowse link
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 multiple interactions ISO Ketoconazole promotes the reaction [Calcitriol results in increased expression of HSD17B2 mRNA] CTD PMID:12040012 NCBI chr19:50,246,404...50,317,892
Ensembl chr19:50,246,402...50,317,891
JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 multiple interactions
increases expression
ISO Ketoconazole promotes the reaction [Colforsin results in increased expression of HSD17B4 mRNA]
Ketoconazole results in increased expression of HSD17B4 mRNA
CTD PMID:16935330 NCBI chr18:44,810,462...44,897,677
Ensembl chr18:44,810,388...44,897,640
JBrowse link
G Hsd17b7 hydroxysteroid (17-beta) dehydrogenase 7 increases expression EXP Ketoconazole results in increased expression of HSD17B7 mRNA CTD PMID:28263823 NCBI chr13:88,288,116...88,308,019
Ensembl chr13:88,288,046...88,307,988
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 decreases expression EXP Ketoconazole results in decreased expression of HSD3B1 mRNA CTD PMID:17229994
G Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 multiple interactions
decreases expression
ISO [Colforsin co-treated with Ketoconazole] results in decreased expression of HSD3B2 mRNA
Ketoconazole results in decreased expression of HSD3B2 mRNA
CTD PMID:16935330 NCBI chr 2:200,712,895...200,722,429
Ensembl chr 2:202,341,422...202,350,929
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 decreases expression EXP Ketoconazole results in decreased expression of HSPD1 mRNA CTD PMID:25787151 NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956
JBrowse link
G Ibsp integrin-binding sialoprotein multiple interactions ISO Ketoconazole inhibits the reaction [Calcifediol results in increased expression of IBSP mRNA] CTD PMID:21542014 NCBI chr14:6,801,200...6,813,987
Ensembl chr14:6,801,204...6,813,945
JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 increases expression
multiple interactions
ISO
EXP
Ketoconazole results in increased expression of IDI1 mRNA
EIF2S1 protein mutant form promotes the reaction [Ketoconazole results in increased expression of IDI1 mRNA]
CTD PMID:16330322, PMID:28263823 NCBI chr17:57,976,266...57,984,036
Ensembl chr17:57,976,268...57,984,036
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 increases expression EXP Ketoconazole results in increased expression of IGFBP1 mRNA CTD PMID:18289764 NCBI chr14:87,448,716...87,453,783
Ensembl chr14:87,448,692...87,453,785
JBrowse link
G Ighe immunoglobulin heavy constant epsilon multiple interactions ISO Bucladesine inhibits the reaction [Ketoconazole inhibits the reaction [IL4 protein results in increased expression of IGHE mRNA alternative form]]; Bucladesine inhibits the reaction [Ketoconazole inhibits the reaction [IL4 protein results in increased expression of IGHE mRNA]]; Ketoconazole inhibits the reaction [IL4 protein results in increased expression of IGHE mRNA alternative form]; Ketoconazole inhibits the reaction [IL4 protein results in increased expression of IGHE mRNA] CTD PMID:12230500 NCBI chr 6:138,066,728...138,068,606 JBrowse link
G Igkc immunoglobulin kappa constant decreases expression EXP Ketoconazole results in decreased expression of IGKC mRNA CTD PMID:18289764
G Il1b interleukin 1 beta multiple interactions
increases expression
ISO
EXP
Ketoconazole inhibits the reaction [[IL1B protein co-treated with IL6 protein] results in increased expression of SAA1 mRNA]; Ketoconazole inhibits the reaction [[IL1B protein co-treated with IL6 protein] results in increased expression of SAA2 mRNA]
Ketoconazole inhibits the reaction [Carbon Tetrachloride results in increased expression of IL1B protein]
Ketoconazole results in increased expression of IL1B mRNA
CTD PMID:17966066, PMID:28138970, PMID:31168027 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 multiple interactions ISO Ketoconazole promotes the reaction [Calcitriol results in increased expression of IL1RL1 mRNA] CTD PMID:12040012 NCBI chr 9:47,133,483...47,184,316
Ensembl chr 9:47,134,034...47,182,170
JBrowse link
G Il33 interleukin 33 affects expression EXP Ketoconazole affects the expression of IL33 mRNA CTD PMID:18355885 NCBI chr 1:248,112,611...248,147,030
Ensembl chr 1:248,132,090...248,147,029
JBrowse link
G Il4 interleukin 4 multiple interactions
decreases expression
decreases secretion
ISO 1-Methyl-3-isobutylxanthine inhibits the reaction [Ketoconazole results in decreased expression of IL4 mRNA]; 1-Methyl-3-isobutylxanthine inhibits the reaction [Ketoconazole results in decreased secretion of IL4 protein]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of Prostaglandin D2]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]]; Bucladesine inhibits the reaction [Ketoconazole inhibits the reaction [IL4 protein results in increased expression of IGHE mRNA alternative form]]; Bucladesine inhibits the reaction [Ketoconazole inhibits the reaction [IL4 protein results in increased expression of IGHE mRNA]]; Bucladesine inhibits the reaction [Ketoconazole results in decreased expression of IL4 mRNA]; Bucladesine inhibits the reaction [Ketoconazole results in decreased secretion of IL4 protein]; Colforsin inhibits the reaction [Ketoconazole results in decreased expression of IL4 mRNA]; Colforsin inhibits the reaction [Ketoconazole results in decreased secretion of IL4 protein]; Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]; Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of Prostaglandin D2]; Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased degradation of NFKBIA protein]; Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CCL5 mRNA]; Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CXCL8 mRNA]; Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]; Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]; Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased secretion of Thromboxane B2]; Ketoconazole inhibits the reaction [IL4 protein results in increased chemical synthesis of Cyclic AMP]; Ketoconazole inhibits the reaction [IL4 protein results in increased expression of IGHE mRNA alternative form]; Ketoconazole inhibits the reaction [IL4 protein results in increased expression of IGHE mRNA]; Ketoconazole promotes the reaction [[Poly I-C co-treated with IL4 protein] results in increased secretion of Dinoprostone] CTD PMID:11886533, PMID:12230500, PMID:15284827, PMID:23688403 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il5 interleukin 5 multiple interactions
decreases secretion
decreases expression
ISO 1-Methyl-3-isobutylxanthine inhibits the reaction [Ketoconazole results in decreased expression of IL5 mRNA]; 1-Methyl-3-isobutylxanthine inhibits the reaction [Ketoconazole results in decreased secretion of IL5 protein]; Bucladesine inhibits the reaction [Ketoconazole results in decreased expression of IL5 mRNA]; Bucladesine inhibits the reaction [Ketoconazole results in decreased secretion of IL5 protein]; Colforsin inhibits the reaction [Ketoconazole results in decreased expression of IL5 mRNA]; Colforsin inhibits the reaction [Ketoconazole results in decreased secretion of IL5 protein] CTD PMID:11886533, PMID:15284827 NCBI chr10:39,066,716...39,069,587
Ensembl chr10:39,066,716...39,069,587
JBrowse link
G Il6 interleukin 6 multiple interactions ISO
EXP
Ketoconazole inhibits the reaction [[IL1B protein co-treated with IL6 protein] results in increased expression of SAA1 mRNA]; Ketoconazole inhibits the reaction [[IL1B protein co-treated with IL6 protein] results in increased expression of SAA2 mRNA]; Ketoconazole inhibits the reaction [IL6 protein results in increased expression of HAMP mRNA]
Ketoconazole inhibits the reaction [Carbon Tetrachloride results in increased expression of IL6 protein]
CTD PMID:17966066, PMID:31168027 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Inhbe inhibin subunit beta E increases expression ISO Ketoconazole results in increased expression of INHBE mRNA CTD PMID:15342952, PMID:17175557, PMID:17567588 NCBI chr 7:70,641,423...70,642,848
Ensembl chr 7:70,640,075...70,643,169
JBrowse link
G Kcna5 potassium voltage-gated channel subfamily A member 5 decreases activity ISO Ketoconazole results in decreased activity of KCNA5 protein CTD PMID:9694927 NCBI chr 4:159,077,195...159,079,003
Ensembl chr 4:159,077,195...159,079,003
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 affects activity
decreases response to substance
multiple interactions
decreases activity
affects localization
ISO Ketoconazole affects the activity of KCNH2 protein mutant form
KCNH2 protein mutant form results in decreased susceptibility to Ketoconazole
[Ketoconazole co-treated with desloratadine co-treated with Loratadine] results in decreased activity of KCNH2 protein; [Ketoconazole co-treated with desloratadine] results in decreased activity of KCNH2 protein; [Ketoconazole co-treated with Loratadine] results in decreased activity of KCNH2 protein; Ketoconazole binds to and results in decreased activity of KCNH2 protein; Terfenadine promotes the reaction [Ketoconazole results in decreased activity of KCNH2 protein]
Ketoconazole results in decreased activity of KCNH2; Ketoconazole results in decreased activity of KCNH2 protein
Ketoconazole affects the localization of KCNH2; Ketoconazole affects the localization of KCNH2 protein mutant form
CTD PMID:9694927, PMID:15272206, PMID:16542653, PMID:17965736, PMID:24052561, PMID:29143966 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
G Klk6 kallikrein related-peptidase 6 multiple interactions ISO Ketoconazole promotes the reaction [Calcitriol results in increased expression of KLK6 mRNA] CTD PMID:26485663 NCBI chr 1:99,762,195...99,769,486
Ensembl chr 1:99,762,253...99,769,488
JBrowse link
G Lcn2 lipocalin 2 decreases expression EXP Ketoconazole results in decreased expression of LCN2 mRNA CTD PMID:18289764 NCBI chr 3:11,414,189...11,417,534
Ensembl chr 3:11,414,186...11,417,546
JBrowse link
G Lhb luteinizing hormone subunit beta multiple interactions EXP Ketoconazole inhibits the reaction [LHB protein results in increased abundance of Testosterone] CTD PMID:7589908 NCBI chr 1:101,409,992...101,413,725
Ensembl chr 1:101,410,019...101,413,724
JBrowse link
G Lhx1 LIM homeobox 1 increases expression EXP Ketoconazole results in increased expression of LHX1 mRNA CTD PMID:28263823 NCBI chr10:71,843,991...71,849,293
Ensembl chr10:71,843,991...71,849,293
JBrowse link
G Lox lysyl oxidase affects expression EXP Ketoconazole affects the expression of LOX mRNA CTD PMID:18355885 NCBI chr18:47,500,320...47,577,819
Ensembl chr18:47,500,330...47,577,819
JBrowse link
G Lrrc75a leucine rich repeat containing 75A increases expression EXP Ketoconazole results in increased expression of LRRC75A mRNA CTD PMID:28263823 NCBI chr10:48,929,519...48,947,606
Ensembl chr10:48,930,416...48,944,304
JBrowse link
G Lss lanosterol synthase increases expression ISO Ketoconazole results in increased expression of LSS mRNA CTD PMID:15342952, PMID:17175557, PMID:17567588 NCBI chr20:12,844,522...12,870,474
Ensembl chr20:12,842,884...12,870,497
JBrowse link
G Macroh2a1 macroH2A.1 histone affects expression EXP Ketoconazole affects the expression of MACROH2A1 mRNA CTD PMID:18355885 NCBI chr17:9,282,109...9,344,698
Ensembl chr17:9,282,675...9,344,678
JBrowse link
G Madcam1 mucosal vascular addressin cell adhesion molecule 1 multiple interactions ISO Ketoconazole inhibits the reaction [TNF protein results in increased expression of MADCAM1 protein] CTD PMID:12388057 NCBI chr 7:12,918,352...12,922,509
Ensembl chr 7:12,918,710...12,922,112
JBrowse link
G Manba mannosidase beta affects expression EXP Ketoconazole affects the expression of MANBA mRNA CTD PMID:18355885 NCBI chr 2:240,668,213...240,760,264
Ensembl chr 2:240,668,195...240,760,261
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation
increases expression
ISO
EXP
Ketoconazole results in increased phosphorylation of MAPK8 protein
Ketoconazole results in increased expression of MAPK8 mRNA
CTD PMID:19631732, PMID:25787151 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member multiple interactions ISO [Ketoconazole inhibits the reaction [CYP3A4 protein results in increased susceptibility to Amodiaquine]] which results in decreased expression of MCL1 protein CTD PMID:31629065 NCBI chr 2:197,786,212...197,788,992 JBrowse link
G Mgp matrix Gla protein affects expression EXP Ketoconazole affects the expression of MGP mRNA CTD PMID:18289764 NCBI chr 4:170,856,783...170,860,105
Ensembl chr 4:170,856,751...170,860,225
JBrowse link
G Micb MHC class I polypeptide-related sequence B increases expression ISO Ketoconazole results in increased expression of MICB mRNA CTD PMID:32060585 NCBI chr 1:79,754,587...79,772,092
Ensembl chr 1:79,754,587...79,772,092
JBrowse link
G Mill1 MHC I like leukocyte 1 increases expression ISO Ketoconazole results in increased expression of MICA mRNA CTD PMID:32060585 NCBI chr 1:79,631,266...79,657,943
Ensembl chr 1:79,631,668...79,657,941
JBrowse link
G Mki67 marker of proliferation Ki-67 increases expression ISO Ketoconazole results in increased expression of MKI67 mRNA CTD PMID:25808816 NCBI chr 1:207,993,895...208,020,454
Ensembl chr 1:207,993,895...208,020,454
JBrowse link
G Mlx MAX dimerization protein MLX affects expression EXP Ketoconazole affects the expression of MLX mRNA CTD PMID:18355885 NCBI chr10:88,997,011...89,002,154
Ensembl chr10:88,997,399...89,002,152
JBrowse link
G Mrps18b mitochondrial ribosomal protein S18B affects expression EXP Ketoconazole affects the expression of MRPS18B mRNA CTD PMID:18355885 NCBI chr20:3,344,870...3,350,929
Ensembl chr20:3,344,870...3,350,927
JBrowse link
G Msmo1 methylsterol monooxygenase 1 affects expression
increases expression
multiple interactions
EXP
ISO
Ketoconazole affects the expression of MSMO1 mRNA
Ketoconazole results in increased expression of MSMO1 mRNA
EIF2S1 protein mutant form promotes the reaction [Ketoconazole results in increased expression of MSMO1 mRNA]
CTD PMID:16330322, PMID:18355885 NCBI chr16:26,859,441...26,875,880
Ensembl chr16:26,859,397...26,875,973
JBrowse link
G Mt1 metallothionein 1 increases expression EXP Ketoconazole results in increased expression of MT1A mRNA CTD PMID:18289764 NCBI chr19:11,301,991...11,303,007
Ensembl chr17:78,793,336...78,793,724
JBrowse link
G Ncf1 neutrophil cytosolic factor 1 decreases expression EXP Ketoconazole results in decreased expression of NCF1 mRNA CTD PMID:25787151 NCBI chr12:25,497,104...25,506,300
Ensembl chr12:25,497,104...25,506,300
JBrowse link
G Ncoa1 nuclear receptor coactivator 1 multiple interactions ISO Ketoconazole inhibits the reaction [Chenodeoxycholic Acid promotes the reaction [NR1H4 protein binds to NCOA1 protein]]; Ketoconazole inhibits the reaction [NR1I2 protein binds to NCOA1 protein]; Ketoconazole inhibits the reaction [Paclitaxel promotes the reaction [NR1I2 protein binds to NCOA1 protein]]; Ketoconazole inhibits the reaction [piperine promotes the reaction [NCOA1 protein binds to NR1I2 protein]]; Ketoconazole inhibits the reaction [Rifampin promotes the reaction [NR1I2 protein binds to NCOA1 protein]] CTD PMID:12072427, PMID:16819505, PMID:17438109, PMID:17998298, PMID:23525103, PMID:23707768 NCBI chr 6:28,677,563...28,931,844
Ensembl chr 6:28,677,540...28,931,843
JBrowse link
G Ncor2 nuclear receptor co-repressor 2 multiple interactions ISO Ketoconazole inhibits the reaction [NCOR2 protein binds to NR1I2 protein]; Ketoconazole inhibits the reaction [NR1I2 protein binds to NCOR2 protein] CTD PMID:12072427, PMID:29356861 NCBI chr12:36,871,917...37,033,701
Ensembl chr12:36,871,999...37,033,701
JBrowse link
G Ncr3lg1 natural killer cell cytotoxicity receptor 3 ligand 1 increases expression ISO Ketoconazole results in increased expression of NCR3LG1 mRNA; Ketoconazole results in increased expression of NCR3LG1 protein CTD PMID:32060585 NCBI chr 1:102,078,274...102,093,495 JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions
increases expression
ISO
EXP
[Ketoconazole results in increased activity of AHR protein] which results in increased activity of and results in increased localization of NFE2L2 protein; NFE2L2 protein promotes the reaction [Ketoconazole inhibits the reaction [Benzo(a)pyrene results in increased abundance of Reactive Oxygen Species]]; NFE2L2 protein promotes the reaction [Ketoconazole inhibits the reaction [TNF protein results in increased abundance of Reactive Oxygen Species]]; NFE2L2 protein promotes the reaction [Ketoconazole inhibits the reaction [TNF protein results in increased expression of CXCL8 protein]]
[Ketoconazole co-treated with Carbon Tetrachloride] results in increased expression of NFE2L2 protein
Ketoconazole results in increased expression of NFE2L2 protein
Ketoconazole results in increased expression of NFE2L2 mRNA; Ketoconazole results in increased expression of NFE2L2 protein
CTD PMID:21753779, PMID:31168027 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased degradation of NFKBIA protein] CTD PMID:23688403 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Ngfr nerve growth factor receptor increases expression EXP Ketoconazole results in increased expression of NGFR mRNA CTD PMID:28263823 NCBI chr10:83,389,828...83,408,061
Ensembl chr10:83,389,847...83,408,061
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 increases expression ISO Ketoconazole results in increased expression of NLRP3 mRNA CTD PMID:28138970 NCBI chr10:45,884,324...45,918,290
Ensembl chr10:45,893,018...45,918,254
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression
multiple interactions
ISO
EXP
Ketoconazole results in increased expression of NQO1 mRNA; Ketoconazole results in increased expression of NQO1 protein
[Ketoconazole co-treated with Carbon Tetrachloride] results in increased expression of NQO1 mRNA
AHR promotes the reaction [Ketoconazole results in increased expression of NQO1 mRNA]; AHR promotes the reaction [Ketoconazole results in increased expression of NQO1 protein]; Dactinomycin inhibits the reaction [Ketoconazole results in increased expression of NQO1 mRNA]
CTD PMID:17923278, PMID:21753779, PMID:31168027 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 increases expression ISO Ketoconazole results in increased expression of NR0B2 mRNA CTD PMID:15342952, PMID:17175557 NCBI chr 5:151,776,004...151,779,319
Ensembl chr 5:151,776,004...151,779,319
JBrowse link
G Nr1h2 nuclear receptor subfamily 1, group H, member 2 multiple interactions ISO Ketoconazole inhibits the reaction [TO-901317 results in increased activity of NR1H2 protein] CTD PMID:16819505 NCBI chr 1:100,554,577...100,559,896
Ensembl chr 1:100,554,544...100,559,942
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 multiple interactions EXP
ISO
Ketoconazole inhibits the reaction [Clofibrate results in increased expression of NR1H3 mRNA]
Ketoconazole inhibits the reaction [TO-901317 results in increased activity of NR1H3 protein]
CTD PMID:14690017, PMID:16819505 NCBI chr 3:80,004,130...80,014,197
Ensembl chr 3:80,004,130...80,012,750
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO Ketoconazole inhibits the reaction [Chenodeoxycholic Acid promotes the reaction [NR1H4 protein binds to NCOA1 protein]]; Ketoconazole inhibits the reaction [Chenodeoxycholic Acid results in increased activity of NR1H4 protein] CTD PMID:16819505 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions
decreases response to substance
decreases expression
increases activity
ISO [Ketoconazole co-treated with Rifampin] results in increased activity of NR1I2 protein; Ketoconazole binds to and results in decreased activity of NR1I2 protein; Ketoconazole inhibits the reaction [Corticosterone promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]]; Ketoconazole inhibits the reaction [NCOR2 protein binds to NR1I2 protein]; Ketoconazole inhibits the reaction [NR1I2 protein binds to NCOA1 protein]; Ketoconazole inhibits the reaction [NR1I2 protein binds to NCOR2 protein]; Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [piperine results in increased expression of ABCB1 mRNA]]; Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [piperine results in increased expression of ABCB1 protein]]; Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [piperine results in increased expression of CYP3A4 mRNA]]; Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [piperine results in increased expression of CYP3A4 protein]]; Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of ABCB1 mRNA]]; Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of ABCB1 protein]]; Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]]; Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP3A4 protein]]; Ketoconazole inhibits the reaction [NR1I2 protein results in decreased uptake of and results in decreased metabolism of Glucose]; Ketoconazole inhibits the reaction [Paclitaxel promotes the reaction [NR1I2 protein binds to NCOA1 protein]]; Ketoconazole inhibits the reaction [Paclitaxel results in increased activity of NR1I2 protein]; Ketoconazole inhibits the reaction [piperine promotes the reaction [NCOA1 protein binds to NR1I2 protein]]; Ketoconazole inhibits the reaction [Rifampin binds to and results in increased activity of NR1I2 protein]; Ketoconazole inhibits the reaction [Rifampin promotes the reaction [NR1I2 protein binds to NCOA1 protein]]; Ketoconazole inhibits the reaction [Rifampin promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]]; Ketoconazole inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]
NR1I2 protein mutant form results in decreased susceptibility to Ketoconazole
Ketoconazole inhibits the reaction [Pregnenolone Carbonitrile results in increased activity of NR1I2 protein]
Ketoconazole results in decreased expression of NR1I2 mRNA; Ketoconazole results in decreased expression of NR1I2 protein
Ketoconazole results in increased activity of NR1I2 protein
CTD PMID:12072427, PMID:16608920, PMID:16819505, PMID:17438109, PMID:17998298, PMID:20869355, PMID:21402137, PMID:23525103, PMID:23707768, PMID:25343516, PMID:25680588, PMID:26616219, PMID:29356861 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions
decreases activity
decreases expression
ISO [Ketoconazole co-treated with PK 11195] results in decreased activity of NR1I3 protein alternative form; Ketoconazole binds to and results in decreased activity of NR1I3 protein alternative form; Ketoconazole inhibits the reaction [Dexamethasone results in increased expression of NR1I3 mRNA]; Ketoconazole inhibits the reaction [Phenobarbital results in increased activity of NR1I3 protein]
Ketoconazole results in decreased activity of NR1I3 protein
Ketoconazole inhibits the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased activity of NR1I3 protein]
Ketoconazole results in decreased expression of NR1I3 mRNA
CTD PMID:16608920, PMID:16819505, PMID:20869355 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 affects binding
multiple interactions
decreases activity
ISO Ketoconazole binds to NR3C1 protein
Ketoconazole inhibits the reaction [Dexamethasone binds to and results in increased activity of NR3C1 protein]
Ketoconazole results in decreased activity of NR3C1 protein
CTD PMID:15755314, PMID:16608920, PMID:25000292 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Nrep neuronal regeneration related protein affects expression EXP Ketoconazole affects the expression of NREP mRNA CTD PMID:18355885 NCBI chr18:26,183,753...26,212,796
Ensembl chr18:26,185,259...26,211,445
JBrowse link
G Nsdhl NAD(P) dependent steroid dehydrogenase-like increases expression EXP Ketoconazole results in increased expression of NSDHL mRNA CTD PMID:28263823 NCBI chr  X:152,933,118...152,964,399
Ensembl chr  X:152,933,069...152,964,390
JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator increases expression ISO Ketoconazole results in increased expression of NUPR1 mRNA CTD PMID:15342952, PMID:17175557, PMID:17567588 NCBI chr 1:194,767,484...194,769,519
Ensembl chr 1:194,767,474...194,769,524
JBrowse link
G Oaf out at first homolog affects expression EXP Ketoconazole affects the expression of OAF mRNA CTD PMID:18355885 NCBI chr 8:47,511,718...47,529,689
Ensembl chr 8:47,511,719...47,529,689
JBrowse link
G Ovol1 ovo like transcriptional repressor 1 increases expression ISO Ketoconazole results in increased expression of OVOL1 mRNA; Ketoconazole results in increased expression of OVOL1 protein CTD PMID:26873447 NCBI chr 1:220,927,309...220,938,814
Ensembl chr 1:220,925,605...220,938,814
JBrowse link
G Pc pyruvate carboxylase affects expression EXP Ketoconazole affects the expression of PC mRNA CTD PMID:18355885 NCBI chr 1:219,759,157...219,859,854
Ensembl chr 1:219,759,183...219,859,848
JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 increases expression EXP Ketoconazole results in increased expression of PCSK9 mRNA CTD PMID:28263823 NCBI chr 5:126,031,368...126,053,726
Ensembl chr 5:126,031,368...126,053,726
JBrowse link
G Pecr peroxisomal trans-2-enoyl-CoA reductase affects expression EXP Ketoconazole affects the expression of PECR mRNA CTD PMID:18355885 NCBI chr 9:79,601,937...79,630,547
Ensembl chr 9:79,601,901...79,630,536
JBrowse link
G Plekha4 pleckstrin homology domain containing A4 increases expression EXP Ketoconazole results in increased expression of PLEKHA4 mRNA CTD PMID:28263823 NCBI chr 1:101,517,702...101,540,802
Ensembl chr 1:101,517,714...101,540,802
JBrowse link
G Pmvk phosphomevalonate kinase increases expression EXP Ketoconazole results in increased expression of PMVK mRNA CTD PMID:28263823 NCBI chr 2:188,784,329...188,793,890
Ensembl chr 2:188,784,222...188,793,895
JBrowse link
G Pomc proopiomelanocortin decreases expression ISO Ketoconazole results in decreased expression of POMC protein modified form CTD PMID:25808816 NCBI chr 6:28,382,937...28,388,771
Ensembl chr 6:28,382,962...28,388,967
JBrowse link
G Por cytochrome p450 oxidoreductase affects expression
increases expression
multiple interactions
EXP
ISO
Ketoconazole affects the expression of POR mRNA
Ketoconazole results in increased expression of POR protein
Ketoconazole affects the reaction [[NADP co-treated with CYP1A2 protein co-treated with CYP2C8 protein co-treated with CYP2C9 protein co-treated with CYP2C19 protein co-treated with CYP2D6 protein co-treated with CYP3A4 protein co-treated with POR protein] results in increased metabolism of 1-(3-(4-phenoxyphenoxy)-2-oxopropyl)indole-5-carboxylic acid]
CTD PMID:17966066, PMID:18355885, PMID:24120545 NCBI chr12:23,998,411...24,017,063
Ensembl chr12:23,998,411...24,046,814
JBrowse link
G Pou5f1 POU class 5 homeobox 1 decreases expression ISO Ketoconazole results in decreased expression of POU5F1 mRNA CTD PMID:16574651 NCBI chr20:3,747,231...3,751,994
Ensembl chr20:3,747,221...3,751,994
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions EXP Ketoconazole inhibits the reaction [Clofibrate results in increased expression of PPARA mRNA] CTD PMID:14690017 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Ppp2cb protein phosphatase 2 catalytic subunit beta decreases expression EXP Ketoconazole results in decreased expression of PPP2CB mRNA CTD PMID:25787151 NCBI chr16:62,273,276...62,294,767
Ensembl chr16:62,273,276...62,294,769
JBrowse link
G Prdx3 peroxiredoxin 3 decreases expression EXP Ketoconazole results in decreased expression of PRDX3 mRNA CTD PMID:25787151 NCBI chr 1:282,238,774...282,251,193
Ensembl chr 1:282,238,773...282,251,257
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase multiple interactions
increases response to substance
increases expression
EXP 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [Ketoconazole results in increased expression of PRKN mRNA]; 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [Ketoconazole results in increased expression of PRKN protein]; tempol inhibits the reaction [Ketoconazole results in increased expression of PRKN mRNA]; tempol inhibits the reaction [Ketoconazole results in increased expression of PRKN protein]
PRKN protein results in increased susceptibility to Ketoconazole
Ketoconazole results in increased expression of PRKN mRNA; Ketoconazole results in increased expression of PRKN protein
CTD PMID:25787151 NCBI chr 1:48,880,015...50,069,998 JBrowse link
G Prl prolactin decreases expression EXP Ketoconazole results in decreased expression of PRL mRNA CTD PMID:25808816 NCBI chr17:39,814,236...39,824,299
Ensembl chr17:39,814,244...39,824,299
JBrowse link
G Ptger2 prostaglandin E receptor 2 multiple interactions
increases response to substance
ISO PTGER2 protein promotes the reaction [Ketoconazole inhibits the reaction [TNF protein results in increased expression of CCL2 protein]]; PTGER2 protein promotes the reaction [Ketoconazole inhibits the reaction [TNF protein results in increased expression of CCL27 protein]]; PTGER2 protein promotes the reaction [Ketoconazole inhibits the reaction [TNF protein results in increased expression of CCL5 protein]]
PTGER2 protein results in increased susceptibility to Ketoconazole
CTD PMID:16784723 NCBI chr15:19,336,029...19,349,759
Ensembl chr15:19,338,175...19,350,210
JBrowse link
G Ptger3 prostaglandin E receptor 3 multiple interactions
increases response to substance
ISO PTGER3 protein promotes the reaction [Ketoconazole inhibits the reaction [TNF protein results in increased expression of CCL2 protein]]; PTGER3 protein promotes the reaction [Ketoconazole inhibits the reaction [TNF protein results in increased expression of CCL27 protein]]; PTGER3 protein promotes the reaction [Ketoconazole inhibits the reaction [TNF protein results in increased expression of CCL5 protein]]
PTGER3 protein results in increased susceptibility to Ketoconazole
CTD PMID:16784723 NCBI chr 2:263,895,093...263,979,682
Ensembl chr 2:263,895,241...263,979,698
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO Bucladesine inhibits the reaction [Ketoconazole inhibits the reaction [Dinoprostone results in increased expression of PTGS2 mRNA]]; Bucladesine inhibits the reaction [Ketoconazole inhibits the reaction [Dinoprostone results in increased expression of PTGS2 protein]]; Ketoconazole inhibits the reaction [Dinoprostone promotes the reaction [ATF1 protein modified form binds to PTGS2 promoter]]; Ketoconazole inhibits the reaction [Dinoprostone promotes the reaction [CREB1 protein modified form binds to PTGS2 promoter]]; Ketoconazole inhibits the reaction [Dinoprostone results in increased expression of PTGS2 mRNA]; Ketoconazole inhibits the reaction [Dinoprostone results in increased expression of PTGS2 protein] CTD PMID:12164941 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Pth parathyroid hormone multiple interactions EXP Ketoconazole inhibits the reaction [25-hydroxyvitamin D results in decreased expression of PTH mRNA] CTD PMID:18304585 NCBI chr 1:178,215,829...178,218,761
Ensembl chr 1:178,215,829...178,218,761
JBrowse link
G Rarb retinoic acid receptor, beta increases expression EXP Ketoconazole results in increased expression of RARB mRNA CTD PMID:28263823 NCBI chr15:9,915,223...10,262,599
Ensembl chr15:10,120,206...10,262,599
JBrowse link
G Rbl2 RB transcriptional corepressor like 2 affects expression EXP Ketoconazole affects the expression of RBL2 mRNA CTD PMID:18355885 NCBI chr19:17,300,088...17,346,865
Ensembl chr19:17,300,089...17,346,808
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP Ketoconazole inhibits the reaction [Carbon Tetrachloride results in increased expression of RELA protein] CTD PMID:31168027 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Ren renin decreases expression ISO Ketoconazole results in decreased expression of REN protein CTD PMID:2632720 NCBI chr13:50,502,724...50,513,953
Ensembl chr13:50,502,724...50,514,151
JBrowse link
G Rflna refilin A increases expression EXP Ketoconazole results in increased expression of RFLNA mRNA CTD PMID:28263823 NCBI chr12:37,038,732...37,047,628
Ensembl chr12:37,038,733...37,047,628
JBrowse link
G Rnf41 ring finger protein 41 increases expression EXP Ketoconazole results in increased expression of RNF41 mRNA CTD PMID:25787151 NCBI chr 7:2,827,242...2,854,230
Ensembl chr 7:2,827,247...2,852,681
JBrowse link
G RT1-S3 RT1 class Ib, locus S3 affects expression EXP Ketoconazole affects the expression of RT1-S3 mRNA CTD PMID:18355885 NCBI chr20:3,176,124...3,180,825
Ensembl chr20:3,176,107...3,179,818
JBrowse link
G Runx2 RUNX family transcription factor 2 multiple interactions ISO Ketoconazole inhibits the reaction [Calcifediol results in increased expression of RUNX2 mRNA] CTD PMID:21542014 NCBI chr 9:18,564,743...18,773,092
Ensembl chr 9:18,564,927...18,773,092
JBrowse link
G Sc5d sterol-C5-desaturase increases expression EXP Ketoconazole results in increased expression of SC5D mRNA CTD PMID:28263823 NCBI chr 8:46,525,406...46,537,014
Ensembl chr 8:46,525,400...46,537,050
JBrowse link
G Scd stearoyl-CoA desaturase increases expression EXP Ketoconazole results in increased expression of SCD1 mRNA CTD PMID:28263823 NCBI chr 1:264,159,966...264,173,061
Ensembl chr 1:264,160,129...264,172,729
JBrowse link
G Sema3b semaphorin 3B multiple interactions ISO Ketoconazole promotes the reaction [Calcitriol results in increased expression of SEMA3B mRNA] CTD PMID:12040012 NCBI chr 8:116,353,791...116,362,655
Ensembl chr 8:116,354,073...116,361,343
JBrowse link
G Serpina3m serpin family A member 3M increases expression ISO Ketoconazole results in increased expression of SERPINA3 mRNA CTD PMID:15342952, PMID:17175557 NCBI chr 6:127,808,785...127,816,067
Ensembl chr 6:127,808,785...127,816,055
JBrowse link
G Serpinb1a serpin family B member 1A multiple interactions ISO Ketoconazole promotes the reaction [Calcitriol results in increased expression of SERPINB1 mRNA] CTD PMID:26485663 NCBI chr17:32,903,089...32,911,498
Ensembl chr17:32,904,119...32,911,495
JBrowse link
G Serpinb3 serpin family B member 3 multiple interactions ISO Ketoconazole promotes the reaction [Calcitriol results in decreased expression of SERPINB3 mRNA] CTD PMID:12040012 NCBI chr13:27,186,701...27,193,211
Ensembl chr13:27,187,130...27,192,592
JBrowse link
G Serpinh1 serpin family H member 1 multiple interactions ISO Ketoconazole inhibits the reaction [Tunicamycin results in decreased glycosylation of SERPINH1 protein] CTD PMID:16330322 NCBI chr 1:164,301,010...164,308,306
Ensembl chr 1:164,301,010...164,308,317
JBrowse link
G Sh3gl3 SH3 domain containing GRB2 like 3, endophilin A3 affects expression EXP Ketoconazole affects the expression of SH3GL3 mRNA CTD PMID:18355885 NCBI chr 1:144,069,641...144,200,402
Ensembl chr 1:144,069,638...144,200,397
JBrowse link
G Slc10a1 solute carrier family 10 member 1 multiple interactions EXP [Chenodeoxycholic Acid co-treated with Ketoconazole] results in decreased expression of SLC10A1 mRNA CTD PMID:30985903 NCBI chr 6:104,617,730...104,631,355
Ensembl chr 6:104,617,730...104,631,355
JBrowse link
G Slc18a2 solute carrier family 18 member A2 multiple interactions ISO Ketoconazole inhibits the reaction [Maneb results in decreased expression of SLC18A2 protein]; Ketoconazole inhibits the reaction [Paraquat results in decreased expression of SLC18A2 protein] CTD PMID:22334051 NCBI chr 1:280,397,831...280,457,968
Ensembl chr 1:280,423,079...280,457,148
JBrowse link
G Slc2a3 solute carrier family 2 member 3 decreases expression ISO Ketoconazole results in decreased expression of SLC2A3 mRNA CTD PMID:15342952, PMID:17567588 NCBI chr 4:155,549,991...155,626,018
Ensembl chr 4:155,408,233...155,631,856
JBrowse link
G Slc47a1 solute carrier family 47 member 1 multiple interactions ISO Ketoconazole inhibits the reaction [SLC47A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:47,631,425...47,685,379
Ensembl chr10:47,632,192...47,666,921
JBrowse link
G Slc47a2 solute carrier family 47 member 2 multiple interactions ISO Ketoconazole inhibits the reaction [SLC47A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:47,587,909...47,631,373
Ensembl chr10:47,588,497...47,630,799
JBrowse link
G Slc6a6 solute carrier family 6 member 6 affects expression EXP Ketoconazole affects the expression of SLC6A6 mRNA CTD PMID:18355885 NCBI chr 4:123,638,619...123,713,469
Ensembl chr 4:123,642,210...123,713,464
JBrowse link
G Slco1a4 solute carrier organic anion transporter family, member 1a4 affects expression EXP Ketoconazole affects the expression of SLCO1A4 mRNA CTD PMID:18355885 NCBI chr 4:175,969,549...176,026,227
Ensembl chr 4:175,969,549...176,026,163
JBrowse link
G Sphk1 sphingosine kinase 1 increases expression EXP Ketoconazole results in increased expression of SPHK1 mRNA CTD PMID:25787151 NCBI chr10:105,498,728...105,504,401
Ensembl chr10:105,498,728...105,504,393
JBrowse link
G Sqle squalene epoxidase increases expression EXP Ketoconazole results in increased expression of SQLE mRNA CTD PMID:28263823 NCBI chr 7:99,609,929...99,624,803
Ensembl chr 7:99,609,191...99,624,732
JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 increases expression EXP Ketoconazole results in increased expression of SREBF2 mRNA CTD PMID:28263823 NCBI chr 7:123,381,082...123,438,605
Ensembl chr 7:123,381,077...123,438,603
JBrowse link
G St13 ST13, Hsp70 interacting protein affects expression EXP Ketoconazole affects the expression of ST13 mRNA CTD PMID:18355885 NCBI chr 7:122,585,770...122,635,731
Ensembl chr 7:122,585,771...122,635,731
JBrowse link
G Star steroidogenic acute regulatory protein increases expression ISO Ketoconazole results in increased expression of STAR mRNA CTD PMID:10960482 NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847
JBrowse link
G Stard4 StAR-related lipid transfer domain containing 4 increases expression EXP Ketoconazole results in increased expression of STARD4 mRNA CTD PMID:28263823 NCBI chr18:25,982,210...25,997,555
Ensembl chr18:25,984,638...25,997,555
JBrowse link
G Stat1 signal transducer and activator of transcription 1 increases expression
multiple interactions
EXP
ISO
Ketoconazole results in increased expression of STAT1 mRNA
Ketoconazole inhibits the reaction [Biological Products results in increased phosphorylation of and results in increased activity of STAT1 protein]
CTD PMID:24471457, PMID:25787151 NCBI chr 9:54,287,540...54,327,958
Ensembl chr 9:54,287,541...54,484,533
JBrowse link
G Stbd1 starch binding domain 1 affects expression EXP Ketoconazole affects the expression of STBD1 mRNA CTD PMID:18355885 NCBI chr14:16,976,355...16,979,760
Ensembl chr14:16,976,356...16,979,760
JBrowse link
G Stmn1 stathmin 1 affects expression EXP Ketoconazole affects the expression of STMN1 mRNA CTD PMID:18355885 NCBI chr 5:152,680,412...152,686,807
Ensembl chr 5:152,680,407...152,686,806
JBrowse link
G Stra8 stimulated by retinoic acid 8 increases expression ISO Ketoconazole results in increased expression of STRA8 mRNA CTD PMID:16461896 NCBI chr 4:62,447,724...62,474,802
Ensembl chr 4:62,457,694...62,473,360
JBrowse link
G Sycp3 synaptonemal complex protein 3 increases expression ISO Ketoconazole results in increased expression of SYCP3 mRNA CTD PMID:16574651 NCBI chr 7:29,029,887...29,044,344
Ensembl chr 7:29,029,263...29,044,251
JBrowse link
G Tagln transgelin decreases expression ISO Ketoconazole results in decreased expression of TAGLN mRNA CTD PMID:17175557 NCBI chr 8:50,222,895...50,228,369
Ensembl chr 8:50,222,896...50,231,357
JBrowse link
G Tat tyrosine aminotransferase decreases expression ISO Ketoconazole results in decreased expression of TAT mRNA CTD PMID:16608920, PMID:25000292 NCBI chr19:41,675,639...41,686,195
Ensembl chr19:41,675,355...41,686,229
JBrowse link
G Tex261 testis expressed 261 affects expression EXP Ketoconazole affects the expression of TEX261 mRNA CTD PMID:18355885 NCBI chr 4:115,446,830...115,454,035
Ensembl chr 4:115,448,708...115,453,659
JBrowse link
G Th tyrosine hydroxylase multiple interactions ISO Ketoconazole inhibits the reaction [Maneb results in decreased expression of TH protein]; Ketoconazole inhibits the reaction [Nicotine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of TH protein]]; Ketoconazole inhibits the reaction [Paraquat results in decreased expression of TH protein] CTD PMID:19594327, PMID:22334051 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
JBrowse link
G Timm10b translocase of inner mitochondrial membrane 10B affects expression EXP Ketoconazole affects the expression of TIMM10B mRNA CTD PMID:18355885 NCBI chr 1:170,471,265...170,474,111
Ensembl chr 1:170,471,238...170,474,113
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 decreases expression EXP Ketoconazole results in decreased expression of TIMP1 mRNA CTD PMID:18289764 NCBI chr  X:1,364,771...1,369,451
Ensembl chr  X:1,364,786...1,369,384
JBrowse link
G Tmprss2 transmembrane serine protease 2 multiple interactions ISO [Goserelin co-treated with Dutasteride co-treated with bicalutamide co-treated with Ketoconazole] results in decreased expression of TMPRSS2 protein CTD PMID:24323034 NCBI chr11:38,063,914...38,103,406
Ensembl chr11:38,063,915...38,103,290
JBrowse link
G Tmsb10 thymosin, beta 10 decreases expression EXP Ketoconazole results in decreased expression of TMSB10 mRNA CTD PMID:18289764 NCBI chr 4:100,882,216...100,883,303
Ensembl chr 4:100,882,216...100,883,275
JBrowse link
G Tnf tumor necrosis factor increases expression
multiple interactions
ISO
EXP
Ketoconazole results in increased expression of TNF mRNA
Ketoconazole inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF protein]
Ketoconazole inhibits the reaction [TNF protein results in increased expression of MADCAM1 protein]
AHR protein promotes the reaction [Ketoconazole inhibits the reaction [TNF protein results in increased abundance of Reactive Oxygen Species]]; AHR protein promotes the reaction [Ketoconazole inhibits the reaction [TNF protein results in increased expression of CXCL8 protein]]; Dinoprostone deficiency inhibits the reaction [Ketoconazole inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]]; Dinoprostone deficiency inhibits the reaction [Ketoconazole inhibits the reaction [TNF protein results in increased expression of CCL2 protein]]; Dinoprostone deficiency inhibits the reaction [Ketoconazole inhibits the reaction [TNF protein results in increased expression of CCL27 mRNA]]; Dinoprostone deficiency inhibits the reaction [Ketoconazole inhibits the reaction [TNF protein results in increased expression of CCL27 protein]]; Dinoprostone deficiency inhibits the reaction [Ketoconazole inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA]]; Dinoprostone deficiency inhibits the reaction [Ketoconazole inhibits the reaction [TNF protein results in increased expression of CCL5 protein]]; Ketoconazole inhibits the reaction [[Amiodarone co-treated with CYP3A4 protein] results in increased expression of TNF mRNA]; Ketoconazole inhibits the reaction [[desethylamiodarone co-treated with CYP3A4 protein] results in increased expression of TNF mRNA]; Ketoconazole inhibits the reaction [Calcifediol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]]; Ketoconazole inhibits the reaction [Calcifediol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]]; Ketoconazole inhibits the reaction [CYP26A1 protein inhibits the reaction [Tretinoin results in increased activity of TNF protein]]; Ketoconazole inhibits the reaction [TNF protein results in increased abundance of Reactive Oxygen Species]; Ketoconazole inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]; Ketoconazole inhibits the reaction [TNF protein results in increased expression of CCL2 protein]; Ketoconazole inhibits the reaction [TNF protein results in increased expression of CCL27 mRNA]; Ketoconazole inhibits the reaction [TNF protein results in increased expression of CCL27 protein]; Ketoconazole inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA]; Ketoconazole inhibits the reaction [TNF protein results in increased expression of CCL5 protein]; Ketoconazole inhibits the reaction [TNF protein results in increased expression of CXCL8 protein]; Ketoconazole inhibits the reaction [TNF protein results in increased secretion of Thromboxane B2]; Ketoconazole promotes the reaction [TNF protein results in increased secretion of Dinoprostone]; NFE2L2 protein promotes the reaction [Ketoconazole inhibits the reaction [TNF protein results in increased abundance of Reactive Oxygen Species]]; NFE2L2 protein promotes the reaction [Ketoconazole inhibits the reaction [TNF protein results in increased expression of CXCL8 protein]]; PTGER2 protein promotes the reaction [Ketoconazole inhibits the reaction [TNF protein results in increased expression of CCL2 protein]]; PTGER2 protein promotes the reaction [Ketoconazole inhibits the reaction [TNF protein results in increased expression of CCL27 protein]]; PTGER2 protein promotes the reaction [Ketoconazole inhibits the reaction [TNF protein results in increased expression of CCL5 protein]]; PTGER3 protein promotes the reaction [Ketoconazole inhibits the reaction [TNF protein results in increased expression of CCL2 protein]]; PTGER3 protein promotes the reaction [Ketoconazole inhibits the reaction [TNF protein results in increased expression of CCL27 protein]]; PTGER3 protein promotes the reaction [Ketoconazole inhibits the reaction [TNF protein results in increased expression of CCL5 protein]]
CTD PMID:11135059, PMID:12388057, PMID:15703382, PMID:16784723, PMID:21753779, PMID:22785256, PMID:25808816, PMID:31168027 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A increases expression ISO Ketoconazole results in increased expression of TNFRSF1A mRNA CTD PMID:25808816 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633
JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B increases expression ISO
EXP
Ketoconazole results in increased expression of TNFRSF1B mRNA CTD PMID:25808816 NCBI chr 5:163,136,390...163,167,299
Ensembl chr 5:163,136,390...163,167,299
JBrowse link
G Tnfsf10 TNF superfamily member 10 multiple interactions ISO Ketoconazole inhibits the reaction [CYP26A1 protein inhibits the reaction [Tretinoin results in increased activity of TNFSF10 protein]] CTD PMID:15703382 NCBI chr 2:113,008,008...113,026,899
Ensembl chr 2:113,007,549...113,026,899
JBrowse link
G Tp63 tumor protein p63 decreases expression ISO Ketoconazole results in decreased expression of TRP63 mRNA CTD PMID:25808816 NCBI chr11:78,234,853...78,456,559
Ensembl chr11:78,234,800...78,456,501
JBrowse link
G Tp73 tumor protein p73 decreases expression EXP Ketoconazole results in decreased expression of TP73 mRNA CTD PMID:25808816 NCBI chr 5:171,355,876...171,415,354
Ensembl chr 5:171,355,876...171,415,354
JBrowse link
G Tslp thymic stromal lymphopoietin multiple interactions ISO 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]]; Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]; Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein] CTD PMID:23688403 NCBI chr18:25,613,601...25,618,066
Ensembl chr18:25,613,831...25,617,361
JBrowse link
G Uba52 ubiquitin A-52 residue ribosomal protein fusion product 1 affects expression EXP Ketoconazole affects the expression of UBA52 mRNA CTD PMID:18355885 NCBI chr16:20,668,925...20,671,127
Ensembl chr16:20,668,971...20,671,127
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 affects expression
decreases expression
decreases activity
multiple interactions
EXP
ISO
Ketoconazole affects the expression of UGT1A1 mRNA
Ketoconazole results in decreased expression of UGT1A1 mRNA
Ketoconazole results in decreased activity of UGT1A1 protein
[Ketoconazole results in decreased activity of UGT1A1 protein] which results in decreased metabolism of irinotecan
CTD PMID:16608920, PMID:18355885, PMID:22447115 NCBI chr 9:95,295,701...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt2a1 UDP glucuronosyltransferase family 2 member A1 affects expression EXP Ketoconazole affects the expression of UGT2A1 mRNA CTD PMID:18355885 NCBI chr14:22,192,970...22,217,094 JBrowse link
G Ugt2b17 UDP glucuronosyltransferase family 2 member B17 affects expression EXP Ketoconazole affects the expression of UGT2B1 mRNA CTD PMID:18355885 NCBI chr14:22,724,399...22,736,148
Ensembl chr14:22,724,070...22,825,444
JBrowse link
G Vdr vitamin D receptor multiple interactions ISO Ketoconazole inhibits the reaction [Calcifediol promotes the reaction [[[CD3G protein binds to CD3D protein binds to CD3E protein binds to CD247 protein] which co-treated with CD28 protein] results in increased expression of VDR protein]]; Ketoconazole inhibits the reaction [Vitamin D analog results in increased activity of VDR protein] CTD PMID:16280049, PMID:24792400 NCBI chr 7:139,344,452...139,394,138
Ensembl chr 7:139,342,063...139,394,166
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO Ketoconazole inhibits the reaction [CYP3A4 protein promotes the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]]; Ketoconazole inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA] CTD PMID:21566342 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Vim vimentin affects expression EXP Ketoconazole affects the expression of VIM mRNA CTD PMID:18289764 NCBI chr17:80,882,715...80,891,200
Ensembl chr17:80,882,666...80,891,212
JBrowse link
G Wipi1 WD repeat domain, phosphoinositide interacting 1 increases expression ISO Ketoconazole results in increased expression of WIPI1 mRNA CTD PMID:15342952, PMID:17175557 NCBI chr10:97,859,730...97,896,949
Ensembl chr10:97,859,727...97,896,525
JBrowse link
miconazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aacs acetoacetyl-CoA synthetase increases expression ISO Miconazole results in increased expression of AACS mRNA CTD PMID:27462272 NCBI chr12:36,512,393...36,555,694
Ensembl chr12:36,512,393...36,555,694
JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 decreases expression ISO Miconazole results in decreased expression of ABCA1 mRNA CTD PMID:27462272 NCBI chr 5:69,857,717...69,983,042
Ensembl chr 5:69,857,771...69,983,015
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions ISO Miconazole inhibits the reaction [ABCB1 protein results in increased secretion of fluorexon]; Miconazole inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]
Miconazole inhibits the reaction [ABCB1A protein results in increased secretion of fluorexon]
CTD PMID:12235267 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Acaca acetyl-CoA carboxylase alpha increases expression ISO Miconazole results in increased expression of ACACA mRNA CTD PMID:27462272 NCBI chr10:71,519,392...71,719,910
Ensembl chr10:71,536,533...71,719,910
JBrowse link
G Acly ATP citrate lyase increases expression ISO Miconazole results in increased expression of ACLY mRNA CTD PMID:27462272 NCBI chr10:88,392,248...88,442,845
Ensembl chr10:88,392,248...88,442,845
JBrowse link
G Aco1 aconitase 1 increases expression ISO Miconazole results in increased expression of ACO1 mRNA CTD PMID:27462272 NCBI chr 5:56,425,076...56,481,218
Ensembl chr 5:56,425,024...56,481,218
JBrowse link
G Acsbg1 acyl-CoA synthetase bubblegum family member 1 increases expression ISO Miconazole results in increased expression of ACSBG1 mRNA CTD PMID:27462272 NCBI chr 8:59,184,111...59,240,133
Ensembl chr 8:59,184,113...59,239,954
JBrowse link
G Acss2 acyl-CoA synthetase short-chain family member 2 increases expression ISO Miconazole results in increased expression of ACSS2 mRNA CTD PMID:27462272 NCBI chr 3:151,032,925...151,075,856
Ensembl chr 3:151,032,952...151,075,856
JBrowse link
G Adam9 ADAM metallopeptidase domain 9 decreases expression
increases expression
EXP Miconazole results in decreased expression of ADAM9 mRNA
Miconazole results in increased expression of ADAM9 mRNA
CTD PMID:22262564 NCBI chr16:71,810,377...71,887,926
Ensembl chr16:71,810,377...71,887,926
JBrowse link
G Adcy2 adenylate cyclase 2 decreases activity EXP Miconazole results in decreased activity of ADCY2 protein CTD PMID:30607468 NCBI chr 1:37,043,071...37,698,390
Ensembl chr 1:37,507,276...37,698,390
JBrowse link
G Adcy9 adenylate cyclase 9 multiple interactions
increases activity
ISO [Isoproterenol co-treated with Miconazole] results in increased activity of ADCY9 protein alternative form; Calcium inhibits the reaction [Miconazole results in increased activity of ADCY9 protein]; Tacrolimus inhibits the reaction [Calcium inhibits the reaction [Miconazole results in increased activity of ADCY9 protein]]
[Colforsin co-treated with Miconazole] results in increased activity of ADCY9 protein
Miconazole results in increased activity of ADCY9 protein; Miconazole results in increased activity of ADCY9 protein alternative form
CTD PMID:30607468 NCBI chr10:11,392,698...11,515,406
Ensembl chr10:11,392,625...11,512,600
JBrowse link
G Alcam activated leukocyte cell adhesion molecule decreases expression ISO Miconazole results in decreased expression of ALCAM mRNA CTD PMID:27462272 NCBI chr11:50,780,735...50,985,083
Ensembl chr11:50,781,127...50,985,083
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression EXP Miconazole results in increased expression of ALDH1A1 mRNA CTD PMID:22262564 NCBI chr 1:238,222,689...238,264,381
Ensembl chr 1:238,222,521...238,264,330
JBrowse link
G Anapc16 anaphase promoting complex subunit 16 increases expression ISO Miconazole results in increased expression of ANAPC16 mRNA CTD PMID:27462272 NCBI chr20:29,544,626...29,558,928
Ensembl chr20:29,544,629...29,558,321
JBrowse link
G Ankrd10 ankyrin repeat domain 10 decreases expression ISO Miconazole results in decreased expression of ANKRD10 mRNA CTD PMID:27462272 NCBI chr16:83,205,898...83,229,147
Ensembl chr16:83,206,004...83,228,194
JBrowse link
G Ankrd12 ankyrin repeat domain 12 decreases expression ISO Miconazole results in decreased expression of ANKRD12 mRNA CTD PMID:27462272 NCBI chr 9:113,605,683...113,682,482
Ensembl chr 9:113,605,657...113,682,482
JBrowse link
G Ano8 anoctamin 8 decreases expression ISO Miconazole results in decreased expression of ANO8 mRNA CTD PMID:27462272 NCBI chr16:19,884,661...19,894,608
Ensembl chr16:19,886,051...19,894,591
JBrowse link
G Anxa1 annexin A1 decreases expression EXP Miconazole results in decreased expression of ANXA1 mRNA CTD PMID:22262564 NCBI chr 1:237,893,983...237,910,002
Ensembl chr 1:237,893,966...237,910,012
JBrowse link
G Apc APC regulator of WNT signaling pathway decreases expression ISO Miconazole results in decreased expression of APC mRNA CTD PMID:27462272 NCBI chr18:27,011,710...27,106,323
Ensembl chr18:27,047,382...27,105,531
JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 decreases expression EXP Miconazole results in decreased expression of APEX1 mRNA CTD PMID:22262564 NCBI chr15:27,849,943...27,852,083
Ensembl chr15:27,849,979...27,852,082
JBrowse link
G Arf3 ADP-ribosylation factor 3 increases expression ISO Miconazole results in increased expression of ARF3 mRNA CTD PMID:27462272 NCBI chr 7:140,412,463...140,438,751
Ensembl chr 7:140,398,199...140,437,467
JBrowse link
G Arfgef1 ADP ribosylation factor guanine nucleotide exchange factor 1 decreases expression ISO Miconazole results in decreased expression of ARFGEF1 mRNA CTD PMID:27462272 NCBI chr 5:8,666,046...8,760,458
Ensembl chr 5:8,666,200...8,760,458
JBrowse link
G Arhgap5 Rho GTPase activating protein 5 decreases expression ISO Miconazole results in decreased expression of ARHGAP5 mRNA CTD PMID:27462272 NCBI chr 6:73,345,129...73,408,304
Ensembl chr 6:73,345,392...73,405,880
JBrowse link
G Arl2bp ADP-ribosylation factor like GTPase 2 binding protein decreases expression ISO Miconazole results in decreased expression of ARL2BP mRNA CTD PMID:27462272 NCBI chr19:10,753,670...10,763,247
Ensembl chr19:10,753,681...10,763,110
JBrowse link
G Arl5a ADP-ribosylation factor like GTPase 5A decreases expression ISO Miconazole results in decreased expression of ARL5A mRNA CTD PMID:27462272 NCBI chr 3:37,922,544...37,947,434
Ensembl chr 3:37,924,793...37,947,283
JBrowse link
G Arl6ip1 ADP-ribosylation factor like GTPase 6 interacting protein 1 increases expression ISO Miconazole results in increased expression of ARL6IP1 mRNA CTD PMID:27462272 NCBI chr 1:187,770,160...187,779,675
Ensembl chr 1:187,770,160...187,779,675
JBrowse link
G Ash1l ASH1 like histone lysine methyltransferase decreases expression ISO Miconazole results in decreased expression of ASH1L mRNA CTD PMID:27462272 NCBI chr 2:188,252,592...188,389,251
Ensembl chr 2:188,253,220...188,389,250
JBrowse link
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 decreases expression ISO Miconazole results in decreased expression of ATP2B1 mRNA CTD PMID:27462272 NCBI chr 7:41,114,606...41,223,138
Ensembl chr 7:41,114,697...41,220,579
JBrowse link
G Atp6v0c ATPase H+ transporting V0 subunit C increases expression ISO Miconazole results in increased expression of ATP6V0C mRNA CTD PMID:27462272 NCBI chr10:13,537,031...13,543,407
Ensembl chr10:13,537,033...13,542,077
JBrowse link
G Atp6v1g1 ATPase H+ transporting V1 subunit G1 increases expression ISO Miconazole results in increased expression of ATP6V1G1 mRNA CTD PMID:27462272 NCBI chr 5:79,367,663...79,373,843
Ensembl chr 5:79,367,663...79,373,843
JBrowse link
G Atr ATR serine/threonine kinase decreases expression ISO Miconazole results in decreased expression of ATR mRNA CTD PMID:27462272 NCBI chr 8:103,673,578...103,770,886
Ensembl chr 8:103,673,411...103,770,947
JBrowse link
G Atrx ATRX, chromatin remodeler decreases expression ISO Miconazole results in decreased expression of ATRX mRNA CTD PMID:27462272 NCBI chr  X:76,820,110...76,979,155
Ensembl chr  X:76,692,970...76,708,878
Ensembl chr  X:76,692,970...76,708,878
JBrowse link
G Aurkb aurora kinase B increases expression ISO Miconazole results in increased expression of AURKB mRNA CTD PMID:27462272 NCBI chr10:55,625,860...55,632,399
Ensembl chr10:55,626,741...55,634,991
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 increases expression ISO Miconazole results in increased expression of BIRC5 mRNA CTD PMID:27462272 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413
JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 decreases expression ISO Miconazole results in decreased expression of BMPR2 mRNA CTD PMID:27462272 NCBI chr 9:66,568,074...66,683,019
Ensembl chr 9:66,568,074...66,676,494
JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase decreases expression ISO Miconazole results in decreased expression of BRAF mRNA CTD PMID:27462272 NCBI chr 4:67,389,331...67,520,549
Ensembl chr 4:67,396,192...67,520,356
JBrowse link
G Brd9 bromodomain containing 9 increases expression ISO Miconazole results in increased expression of BRD9 mRNA CTD PMID:27462272 NCBI chr 1:31,939,612...31,968,120
Ensembl chr 1:31,939,585...31,967,915
JBrowse link
G Brwd3 bromodomain and WD repeat domain containing 3 decreases expression ISO Miconazole results in decreased expression of BRWD3 mRNA CTD PMID:27462272 NCBI chr  X:79,817,968...79,909,891
Ensembl chr  X:79,824,782...79,909,678
JBrowse link
G Bsn bassoon (presynaptic cytomatrix protein) increases expression ISO Miconazole results in increased expression of BSN mRNA CTD PMID:27462272 NCBI chr 8:116,873,721...116,965,396
Ensembl chr 8:116,873,721...116,965,396
JBrowse link
G Btg1 BTG anti-proliferation factor 1 decreases expression EXP Miconazole results in decreased expression of BTG1 mRNA CTD PMID:22262564 NCBI chr 7:37,812,831...37,815,088
Ensembl chr 7:37,812,831...37,815,088
JBrowse link
G Calcrl calcitonin receptor like receptor decreases expression ISO Miconazole results in decreased expression of CALCRL mRNA CTD PMID:27462272 NCBI chr 3:71,747,938...71,845,487
Ensembl chr 3:71,747,956...71,845,232
JBrowse link
G Camk1 calcium/calmodulin-dependent protein kinase I decreases expression ISO Miconazole results in decreased expression of CAMK1 mRNA CTD PMID:27462272 NCBI chr 4:145,289,300...145,300,146
Ensembl chr 4:145,288,996...145,300,177
JBrowse link
G Casp6 caspase 6 decreases expression EXP Miconazole results in decreased expression of CASP6 mRNA CTD PMID:22262564 NCBI chr 2:235,341,326...235,353,715
Ensembl chr 2:235,341,365...235,353,967
Ensembl chr 2:235,341,365...235,353,967
JBrowse link
G Cat catalase decreases expression EXP Miconazole results in decreased expression of CAT mRNA CTD PMID:22262564 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccar1 cell division cycle and apoptosis regulator 1 decreases expression ISO Miconazole results in decreased expression of CCAR1 mRNA CTD PMID:27462272 NCBI chr20:32,373,443...32,416,044
Ensembl chr20:32,373,443...32,416,044
JBrowse link
G Ccdc88a coiled coil domain containing 88A decreases expression ISO Miconazole results in decreased expression of CCDC88A mRNA CTD PMID:27462272 NCBI chr14:113,771,093...113,936,376
Ensembl chr14:113,867,209...113,932,263
JBrowse link
G Ccng1 cyclin G1 decreases expression ISO Miconazole results in decreased expression of CCNG1 mRNA CTD PMID:27462272 NCBI chr10:25,903,925...25,910,298
Ensembl chr10:25,903,911...25,910,325
JBrowse link
G Ccnl2 cyclin L2 decreases expression ISO Miconazole results in decreased expression of CCNL2 mRNA CTD PMID:27462272 NCBI chr 5:173,256,301...173,268,279
Ensembl chr 5:173,256,637...173,276,169
JBrowse link
G Ccnt2 cyclin T2 decreases expression ISO Miconazole results in decreased expression of CCNT2 mRNA CTD PMID:27462272 NCBI chr13:44,475,959...44,516,892
Ensembl chr13:44,475,970...44,515,739
JBrowse link
G Cct3 chaperonin containing TCP1 subunit 3 increases expression ISO Miconazole results in increased expression of CCT3 mRNA CTD PMID:27462272 NCBI chr 2:187,669,051...187,693,610
Ensembl chr 2:187,668,796...187,693,610
JBrowse link
G Cct5 chaperonin containing TCP1 subunit 5 increases expression ISO Miconazole results in increased expression of CCT5 mRNA CTD PMID:27462272 NCBI chr 2:84,667,578...84,678,730
Ensembl chr 2:84,667,633...84,678,790
JBrowse link
G Cct8 chaperonin containing TCP1 subunit 8 increases expression ISO Miconazole results in increased expression of CCT8 mRNA CTD PMID:27462272 NCBI chr11:27,130,172...27,141,881
Ensembl chr11:27,130,172...27,141,881
JBrowse link
G Cdca2 cell division cycle associated 2 increases expression ISO Miconazole results in increased expression of CDCA2 mRNA CTD PMID:27462272 NCBI chr15:44,365,396...44,411,601
Ensembl chr15:44,365,405...44,411,004
JBrowse link
G Cdk4 cyclin-dependent kinase 4 increases expression ISO Miconazole results in increased expression of CDK4 mRNA CTD PMID:27462272 NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418
JBrowse link
G Cenpe centromere protein E decreases expression ISO Miconazole results in decreased expression of CENPE mRNA CTD PMID:27462272 NCBI chr 2:240,395,974...240,454,785
Ensembl chr 2:240,396,152...240,454,747
JBrowse link
G Cenpf centromere protein F decreases expression ISO Miconazole results in decreased expression of CENPF mRNA CTD PMID:27462272 NCBI chr13:108,132,499...108,178,609
Ensembl chr13:108,132,499...108,178,609
JBrowse link
G Cfl1 cofilin 1 increases expression ISO Miconazole results in increased expression of CFL1 mRNA CTD PMID:27462272 NCBI chr 1:220,869,805...220,873,337
Ensembl chr 1:220,869,805...220,873,337
JBrowse link
G Chchd2 coiled-coil-helix-coiled-coil-helix domain containing 2 increases expression ISO Miconazole results in increased expression of CHCHD2 mRNA CTD PMID:27462272 NCBI chr 9:101,388,148...101,388,819
Ensembl chr 9:101,388,151...101,388,833
JBrowse link
G Chd1 chromodomain helicase DNA binding protein 1 decreases expression ISO Miconazole results in decreased expression of CHD1 mRNA CTD PMID:27462272 NCBI chr 1:57,692,828...57,756,762
Ensembl chr 1:57,692,836...57,755,485
JBrowse link
G Chml CHM like Rab escort protein decreases expression ISO Miconazole results in decreased expression of CHML mRNA CTD PMID:27462272 NCBI chr13:93,740,759...93,742,624 JBrowse link
G Chmp4b charged multivesicular body protein 4B increases expression ISO Miconazole results in increased expression of CHMP4B mRNA CTD PMID:27462272 NCBI chr 3:150,188,275...150,227,453
Ensembl chr 3:150,188,455...150,227,405
JBrowse link
G Chpt1 choline phosphotransferase 1 decreases expression ISO Miconazole results in decreased expression of CHPT1 mRNA CTD PMID:27462272 NCBI chr 7:29,019,518...29,070,928
Ensembl chr 7:29,043,916...29,070,928
JBrowse link
G Chtf18 chromosome transmission fidelity factor 18 increases expression ISO Miconazole results in increased expression of CHTF18 mRNA CTD PMID:27462272 NCBI chr10:15,090,762...15,098,825
Ensembl chr10:15,090,316...15,098,791
JBrowse link
G Clk1 CDC-like kinase 1 decreases expression ISO Miconazole results in decreased expression of CLK1 mRNA CTD PMID:27462272 NCBI chr 9:65,296,777...65,308,017
Ensembl chr 9:65,296,778...65,307,995
JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression ISO Miconazole results in decreased expression of COL1A1 mRNA CTD PMID:27462272 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Col5a1 collagen type V alpha 1 chain decreases expression ISO Miconazole results in decreased expression of COL5A1 mRNA CTD PMID:27462272 NCBI chr 3:6,430,180...6,581,010
Ensembl chr 3:6,430,201...6,578,882
JBrowse link
G Copb2 COPI coat complex subunit beta 2 increases expression ISO Miconazole results in increased expression of COPB2 mRNA CTD PMID:27462272 NCBI chr 8:106,582,339...106,603,763 JBrowse link
G Cpsf6 cleavage and polyadenylation specific factor 6 decreases expression ISO Miconazole results in decreased expression of CPSF6 mRNA CTD PMID:27462272 NCBI chr 7:60,385,688...60,417,661
Ensembl chr 7:60,385,688...60,416,925
JBrowse link
G Cramp1 cramped chromatin regulator homolog 1 decreases expression ISO Miconazole results in decreased expression of CRAMP1L mRNA CTD PMID:27462272 NCBI chr10:14,324,799...14,373,413
Ensembl chr10:14,326,802...14,373,334
JBrowse link
G Crebrf CREB3 regulatory factor decreases expression ISO Miconazole results in decreased expression of CREBRF mRNA CTD PMID:27462272 NCBI chr10:16,693,846...16,753,162
Ensembl chr10:16,694,792...16,752,205
JBrowse link
G Crlf1 cytokine receptor-like factor 1 decreases expression ISO Miconazole results in decreased expression of CRLF1 mRNA CTD PMID:27462272 NCBI chr16:20,675,042...20,686,365
Ensembl chr16:20,675,042...20,686,317
JBrowse link
G Cs citrate synthase increases expression ISO Miconazole results in increased expression of CS mRNA CTD PMID:27462272 NCBI chr 7:2,752,680...2,778,963
Ensembl chr 7:2,752,680...2,778,963
JBrowse link
G Csnk1a1 casein kinase 1, alpha 1 decreases expression ISO Miconazole results in decreased expression of CSNK1A1 mRNA CTD PMID:27462272 NCBI chr18:56,887,722...56,910,610
Ensembl chr18:56,887,354...56,918,345
JBrowse link
G Cttnbp2 cortactin binding protein 2 decreases expression ISO Miconazole results in decreased expression of CTTNBP2 mRNA CTD PMID:27462272 NCBI chr 4:42,932,897...43,096,454
Ensembl chr 4:42,932,903...43,096,399
JBrowse link
G Cwf19l2 CWF19 like cell cycle control factor 2 decreases expression ISO Miconazole results in decreased expression of CWF19L2 mRNA CTD PMID:27462272 NCBI chr 6:18,970,616...19,037,176
Ensembl chr 6:18,970,564...19,055,924
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 increases expression ISO Miconazole results in increased expression of CXCR4 mRNA CTD PMID:27462272 NCBI chr13:45,314,952...45,318,856
Ensembl chr13:45,314,933...45,318,878
JBrowse link
G Cyb5b cytochrome b5 type B increases expression ISO Miconazole results in increased expression of CYB5B mRNA CTD PMID:27462272 NCBI chr19:39,357,814...39,391,680
Ensembl chr19:39,357,791...39,393,189
JBrowse link
G Cycs cytochrome c, somatic decreases expression EXP Miconazole results in decreased expression of CYCS mRNA CTD PMID:22262564 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases activity ISO Miconazole results in decreased activity of CYP17A1 protein CTD PMID:31330226 NCBI chr 1:266,422,127...266,429,947
Ensembl chr 1:266,422,132...266,428,239
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases activity ISO Miconazole results in decreased activity of CYP19A1 protein CTD PMID:15554355 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases expression EXP Miconazole results in decreased expression of CYP1A1 mRNA CTD PMID:22262564 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression EXP Miconazole results in increased expression of CYP1A2 mRNA CTD PMID:22262564 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 decreases activity ISO Miconazole results in decreased activity of CYP2C19 protein CTD PMID:21349323 NCBI chr 1:147,713,879...147,814,410
Ensembl chr 1:147,713,892...147,888,007
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 increases expression EXP Miconazole results in increased expression of CYP3A23-3A1 mRNA CTD PMID:12971794 NCBI chr12:11,053,888...11,082,742
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Cyp51 cytochrome P450, family 51 decreases activity
increases expression
decreases response to substance
ISO Miconazole results in decreased activity of CYP51A1 protein
Miconazole results in increased expression of CYP51 mRNA
CYP51A1 gene results in decreased susceptibility to Miconazole
CTD PMID:16989930, PMID:18694951, PMID:27462272, PMID:29337257 NCBI chr 4:27,175,564...27,194,018
Ensembl chr 4:27,175,243...27,194,018
JBrowse link
G Dbt dihydrolipoamide branched chain transacylase E2 decreases expression ISO Miconazole results in decreased expression of DBT mRNA CTD PMID:27462272 NCBI chr 2:219,563,783...219,592,651
Ensembl chr 2:219,563,783...219,592,650
JBrowse link
G Dcaf7 DDB1 and CUL4 associated factor 7 increases expression ISO Miconazole results in increased expression of DCAF7 mRNA CTD PMID:27462272 NCBI chr10:94,231,585...94,254,046
Ensembl chr10:94,231,585...94,254,046
JBrowse link
G Dcc DCC netrin 1 receptor decreases expression ISO Miconazole results in decreased expression of DCC mRNA CTD PMID:27462272 NCBI chr18:66,518,213...67,629,801
Ensembl chr18:66,523,120...67,224,566
JBrowse link
G Dck deoxycytidine kinase increases expression ISO Miconazole results in increased expression of DCK mRNA CTD PMID:27462272 NCBI chr14:20,935,442...20,952,939
Ensembl chr14:20,935,369...20,953,095
JBrowse link
G Ddb1 damage-specific DNA binding protein 1 increases expression ISO Miconazole results in increased expression of DDB1 mRNA CTD PMID:27462272 NCBI chr 1:226,657,561...226,683,356
Ensembl chr 1:226,657,561...226,683,347
JBrowse link
G Ddx5 DEAD-box helicase 5 decreases expression ISO Miconazole results in decreased expression of DDX5 mRNA CTD PMID:27462272 NCBI chr10:94,979,759...94,988,461
Ensembl chr10:94,980,928...94,988,461
JBrowse link
G Ddx59 DEAD-box helicase 59 increases expression ISO Miconazole results in increased expression of DDX59 mRNA CTD PMID:27462272 NCBI chr13:53,299,872...53,324,824
Ensembl chr13:53,299,872...53,324,824
JBrowse link
G Dhcr24 24-dehydrocholesterol reductase increases expression ISO Miconazole results in increased expression of DHCR24 mRNA CTD PMID:27462272 NCBI chr 5:126,164,708...126,188,926
Ensembl chr 5:126,164,674...126,191,206
JBrowse link
G Dhcr7 7-dehydrocholesterol reductase increases expression ISO Miconazole results in increased expression of DHCR7 mRNA CTD PMID:27462272 NCBI chr 1:217,018,916...217,034,890
Ensembl chr 1:217,018,916...217,034,904
JBrowse link
G Dhrs3 dehydrogenase/reductase 3 increases expression ISO Miconazole results in increased expression of DHRS3 mRNA CTD PMID:29337257 NCBI chr 5:162,809,090...162,843,385
Ensembl chr 5:162,808,646...162,843,383
JBrowse link
G Dhx36 DEAH-box helicase 36 decreases expression ISO Miconazole results in decreased expression of DHX36 mRNA CTD PMID:27462272 NCBI chr 2:152,785,844...152,824,549
Ensembl chr 2:152,785,844...152,824,547
JBrowse link
G Dmxl1 Dmx-like 1 decreases expression ISO Miconazole results in decreased expression of DMXL1 mRNA CTD PMID:27462272 NCBI chr18:44,468,762...44,644,769
Ensembl chr18:44,468,784...44,642,050
JBrowse link
G Dnajc10 DnaJ heat shock protein family (Hsp40) member C10 decreases expression EXP Miconazole results in decreased expression of DNAJC10 mRNA CTD PMID:22262564 NCBI chr 3:67,538,289...67,578,308
Ensembl chr 3:67,538,289...67,578,306
JBrowse link
G Dock10 dedicator of cytokinesis 10 decreases expression ISO Miconazole results in decreased expression of DOCK10 mRNA CTD PMID:27462272 NCBI chr 9:86,424,638...86,571,854
NCBI chr 9:86,312,470...86,423,054
Ensembl chr 9:86,312,501...86,571,870
JBrowse link
G Dock11 dedicator of cytokinesis 11 decreases expression ISO Miconazole results in decreased expression of DOCK11 mRNA CTD PMID:27462272 NCBI chr  X:122,507,169...122,690,463
Ensembl chr  X:122,507,374...122,690,465
JBrowse link
G Dph7 diphthamide biosynthesis 7 increases expression ISO Miconazole results in increased expression of DPH7 mRNA CTD PMID:27462272 NCBI chr 3:2,170,193...2,179,101
Ensembl chr 3:2,170,533...2,179,010
JBrowse link
G Dpp8 dipeptidylpeptidase 8 decreases expression ISO Miconazole results in decreased expression of DPP8 mRNA CTD PMID:27462272 NCBI chr 8:70,521,782...70,576,180
Ensembl chr 8:70,522,092...70,573,424
JBrowse link
G Dpysl2 dihydropyrimidinase-like 2 increases expression ISO Miconazole results in increased expression of DPYSL2 mRNA CTD PMID:27462272 NCBI chr15:43,475,640...43,581,725
Ensembl chr15:43,477,629...43,542,939
JBrowse link
G Drd5 dopamine receptor D5 increases expression EXP Miconazole results in increased expression of DRD5 mRNA CTD PMID:22262564 NCBI chr14:77,220,579...77,222,006
Ensembl chr14:77,220,579...77,222,006
JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression EXP Miconazole results in increased expression of DUSP1 mRNA CTD PMID:22262564 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418
JBrowse link
G Dync1h1 dynein cytoplasmic 1 heavy chain 1 increases expression ISO Miconazole results in increased expression of DYNC1H1 mRNA CTD PMID:27462272 NCBI chr 6:134,958,854...135,085,769
Ensembl chr 6:134,958,854...135,085,769
JBrowse link
G Dynlt3 dynein light chain Tctex-type 3 decreases expression ISO Miconazole results in decreased expression of DYNLT3 mRNA CTD PMID:27462272 NCBI chr  X:14,633,342...14,642,356
Ensembl chr  X:14,633,342...14,642,424
JBrowse link
G Dzip3 DAZ interacting zinc finger protein 3 decreases expression ISO Miconazole results in decreased expression of DZIP3 mRNA CTD PMID:27462272 NCBI chr11:54,404,777...54,475,361
Ensembl chr11:54,404,446...54,472,447
JBrowse link
G Eea1 early endosome antigen 1 decreases expression ISO Miconazole results in decreased expression of EEA1 mRNA CTD PMID:27462272 NCBI chr 7:37,101,415...37,186,534
Ensembl chr 7:37,018,459...37,186,732
JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 increases expression ISO Miconazole results in increased expression of EEF1A1 mRNA CTD PMID:27462272 NCBI chr 8:85,838,594...85,841,816
Ensembl chr 8:85,838,869...85,840,818
JBrowse link
G Eef1b2 eukaryotic translation elongation factor 1 beta 2 increases expression ISO Miconazole results in increased expression of EEF1B2 mRNA CTD PMID:27462272 NCBI chr 9:69,953,440...69,956,158
Ensembl chr 9:69,953,440...69,956,160
JBrowse link
G Egr1 early growth response 1 increases expression ISO Miconazole results in increased expression of EGR1 mRNA CTD PMID:27462272 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Eif3a eukaryotic translation initiation factor 3, subunit A decreases expression ISO Miconazole results in decreased expression of EIF3A mRNA CTD PMID:27462272 NCBI chr 1:282,139,809...282,170,017
Ensembl chr 1:282,139,823...282,170,017
JBrowse link
G Eif3c eukaryotic translation initiation factor 3, subunit C increases expression ISO Miconazole results in increased expression of EIF3C mRNA CTD PMID:27462272 NCBI chr 1:197,964,406...197,982,917
Ensembl chr 1:197,964,407...197,982,601
JBrowse link
G Eif5b eukaryotic translation initiation factor 5B decreases expression ISO Miconazole results in decreased expression of EIF5B mRNA CTD PMID:27462272 NCBI chr 9:44,658,724...44,713,518
Ensembl chr 9:44,681,494...44,713,199
JBrowse link
G Elovl5 ELOVL fatty acid elongase 5 increases expression ISO Miconazole results in increased expression of ELOVL5 mRNA CTD PMID:27462272 NCBI chr 8:85,220,941...85,287,449
Ensembl chr 8:85,259,982...85,285,983
JBrowse link
G Elp2 elongator acetyltransferase complex subunit 2 increases expression ISO Miconazole results in increased expression of ELP2 mRNA CTD PMID:27462272 NCBI chr18:16,544,515...16,581,086
Ensembl chr18:16,544,508...16,581,116
JBrowse link
G Ep300 E1A binding protein p300 decreases expression EXP
ISO
Miconazole results in decreased expression of EP300 mRNA CTD PMID:22262564, PMID:27462272 NCBI chr 7:122,818,194...122,889,055
Ensembl chr 7:122,818,975...122,861,296
JBrowse link
G Epha5 EPH receptor A5 decreases expression ISO Miconazole results in decreased expression of EPHA5 mRNA CTD PMID:27462272 NCBI chr14:25,589,312...25,958,258
Ensembl chr14:25,589,762...25,958,227
JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 increases expression
decreases expression
EXP
ISO
Miconazole results in increased expression of ERBB4 mRNA
Miconazole results in decreased expression of ERBB4 mRNA
CTD PMID:22262564, PMID:27462272 NCBI chr 9:75,021,790...76,178,936
Ensembl chr 9:75,021,790...75,528,644
JBrowse link
G Erg28 ergosterol biosynthesis 28 homolog increases expression ISO Miconazole results in increased expression of ERG28 mRNA CTD PMID:27462272 NCBI chr 6:109,683,252...109,692,218
Ensembl chr 6:109,683,253...109,692,218
JBrowse link
G Esf1 ESF1 nucleolar pre-rRNA processing protein homolog decreases expression ISO Miconazole results in decreased expression of ESF1 mRNA CTD PMID:27462272 NCBI chr 3:133,178,591...133,232,358
Ensembl chr 3:133,178,561...133,232,322
JBrowse link
G Etnk1 ethanolamine kinase 1 decreases expression ISO Miconazole results in decreased expression of ETNK1 mRNA CTD PMID:27462272 NCBI chr 4:177,402,904...177,447,047
Ensembl chr 4:177,402,904...177,447,028
JBrowse link
G Exo1 exonuclease 1 increases expression ISO Miconazole results in increased expression of EXO1 mRNA CTD PMID:27462272 NCBI chr13:93,936,989...93,962,749
Ensembl chr13:93,939,022...93,960,342
JBrowse link
G Exoc5 exocyst complex component 5 decreases expression ISO Miconazole results in decreased expression of EXOC5 mRNA CTD PMID:27462272 NCBI chr15:25,888,757...25,933,302
Ensembl chr15:25,887,070...25,933,268
JBrowse link
G Fabp7 fatty acid binding protein 7 decreases expression ISO Miconazole results in decreased expression of FABP7 mRNA CTD PMID:27462272 NCBI chr20:40,769,624...40,773,156
Ensembl chr20:40,769,586...40,773,349
JBrowse link
G Fads1 fatty acid desaturase 1 increases expression ISO Miconazole results in increased expression of FADS1 mRNA CTD PMID:27462272 NCBI chr 1:226,234,034...226,249,118
Ensembl chr 1:226,234,074...226,249,138
JBrowse link
G Fads2 fatty acid desaturase 2 increases expression ISO Miconazole results in increased expression of FADS2 mRNA CTD PMID:27462272 NCBI chr 1:225,906,582...226,152,568
Ensembl chr 1:226,114,413...226,152,524
JBrowse link
G Fam199x family with sequence similarity 199, X-linked decreases expression ISO Miconazole results in decreased expression of FAM199X mRNA CTD PMID:27462272 NCBI chr  X:107,695,491...107,723,594
Ensembl chr  X:107,695,491...107,723,594
JBrowse link
G Fancm FA complementation group M decreases expression ISO Miconazole results in decreased expression of FANCM mRNA CTD PMID:27462272 NCBI chr 6:86,823,195...86,877,067
Ensembl chr 6:86,823,684...86,876,633
JBrowse link
G Far1 fatty acyl CoA reductase 1 decreases expression ISO Miconazole results in decreased expression of FAR1 mRNA CTD PMID:27462272 NCBI chr 1:178,351,674...178,412,838
Ensembl chr 1:178,351,680...178,431,395
JBrowse link
G Fasn fatty acid synthase increases expression ISO Miconazole results in increased expression of FASN mRNA CTD PMID:27462272 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
JBrowse link
G Fbl fibrillarin increases expression ISO Miconazole results in increased expression of FBL mRNA CTD PMID:27462272 NCBI chr 1:85,103,519...85,112,619
Ensembl chr 1:85,103,519...85,112,619
JBrowse link
G Fbn2 fibrillin 2 increases expression ISO Miconazole results in increased expression of FBN2 mRNA CTD PMID:27462272 NCBI chr18:53,068,495...53,272,254
Ensembl chr18:53,068,495...53,181,503
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 increases expression ISO Miconazole results in increased expression of FDFT1 mRNA CTD PMID:27462272 NCBI chr15:46,339,248...46,367,302
Ensembl chr15:46,339,249...46,367,302
JBrowse link
G Fdps farnesyl diphosphate synthase increases expression ISO Miconazole results in increased expression of FDPS mRNA CTD PMID:27462272 NCBI chr 2:188,403,595...188,413,219
Ensembl chr 2:188,392,858...188,413,219
JBrowse link
G Fgfbp3 fibroblast growth factor binding protein 3 increases expression ISO Miconazole results in increased expression of FGFBP3 mRNA CTD PMID:27462272 NCBI chr 1:255,555,050...255,557,055
Ensembl chr 1:255,555,050...255,557,055
JBrowse link
G Fignl2 fidgetin-like 2 decreases expression ISO Miconazole results in decreased expression of FIGNL2 mRNA CTD PMID:27462272 NCBI chr 7:142,693,181...142,716,030 JBrowse link
G Fkbp4 FKBP prolyl isomerase 4 increases expression ISO Miconazole results in increased expression of FKBP4 mRNA CTD PMID:27462272 NCBI chr 4:161,748,993...161,757,447
Ensembl chr 4:161,748,993...161,757,447
JBrowse link
G Fnip1 folliculin interacting protein 1 decreases expression ISO Miconazole results in decreased expression of FNIP1 mRNA CTD PMID:27462272 NCBI chr10:39,786,687...39,870,188 JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression EXP Miconazole results in increased expression of FOS mRNA CTD PMID:22262564 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit decreases expression EXP Miconazole results in decreased expression of FOSL1 mRNA CTD PMID:22262564 NCBI chr 1:220,826,560...220,835,066
Ensembl chr 1:220,826,560...220,835,066
JBrowse link
G Foxm1 forkhead box M1 increases expression ISO Miconazole results in increased expression of FOXM1 mRNA CTD PMID:27462272 NCBI chr 4:161,685,236...161,697,633
Ensembl chr 4:161,685,258...161,696,305
JBrowse link
G Fth1 ferritin heavy chain 1 increases expression ISO Miconazole results in increased expression of FTH1 mRNA CTD PMID:27462272 NCBI chr 1:226,030,940...226,033,228
Ensembl chr 1:226,030,938...226,033,228
JBrowse link
G Fubp1 far upstream element binding protein 1 decreases expression ISO Miconazole results in decreased expression of FUBP1 mRNA CTD PMID:27462272 NCBI chr 2:257,425,676...257,452,745
Ensembl chr 2:257,425,679...257,449,568
JBrowse link
G Fzd3 frizzled class receptor 3 decreases expression ISO Miconazole results in decreased expression of FZD3 mRNA CTD PMID:27462272 NCBI chr15:48,601,259...48,670,257
Ensembl chr15:48,601,266...48,670,257
JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma increases expression ISO Miconazole results in increased expression of GADD45G mRNA CTD PMID:27462272 NCBI chr17:13,391,474...13,393,219
Ensembl chr17:13,391,467...13,393,243
JBrowse link
G Galk1 galactokinase 1 increases expression ISO Miconazole results in increased expression of GALK1 mRNA CTD PMID:27462272 NCBI chr10:104,560,322...104,564,499
Ensembl chr10:104,560,303...104,564,480
JBrowse link
G Ggct gamma-glutamyl cyclotransferase increases expression ISO Miconazole results in increased expression of GGCT mRNA CTD PMID:27462272 NCBI chr 4:85,186,644...85,192,857
Ensembl chr 4:85,186,644...85,192,834
JBrowse link
G Gins2 GINS complex subunit 2 increases expression ISO Miconazole results in increased expression of GINS2 mRNA CTD PMID:27462272 NCBI chr19:54,151,048...54,163,701
Ensembl chr19:54,151,048...54,163,608
JBrowse link
G Gli3 GLI family zinc finger 3 increases expression ISO Miconazole results in increased expression of GLI3 mRNA CTD PMID:27462272 NCBI chr17:52,294,942...52,569,036
Ensembl chr17:52,294,942...52,569,036
JBrowse link
G Glul glutamate-ammonia ligase increases expression ISO Miconazole results in increased expression of GLUL mRNA CTD PMID:27462272 NCBI chr13:71,331,052...71,340,207
Ensembl chr13:71,331,052...71,340,229
JBrowse link
G Golga7 golgin A7 increases expression ISO Miconazole results in increased expression of GOLGA7 mRNA CTD PMID:27462272 NCBI chr16:73,564,172...73,579,389
Ensembl chr16:73,564,243...73,579,382
JBrowse link
G Gpm6b glycoprotein m6b decreases expression ISO Miconazole results in decreased expression of GPM6B mRNA CTD PMID:27462272 NCBI chr  X:29,604,607...29,751,174
Ensembl chr  X:29,607,075...29,648,403
JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 decreases expression ISO Miconazole results in decreased expression of GRIA2 mRNA CTD PMID:27462272 NCBI chr 2:179,584,302...179,704,629
Ensembl chr 2:179,584,308...179,704,629
JBrowse link
G Gsta2 glutathione S-transferase alpha 2 increases expression EXP Miconazole results in increased expression of GSTA2 mRNA CTD PMID:12971794 NCBI chr 8:85,640,081...85,645,621 JBrowse link
G Gtf2f1 general transcription factor IIF subunit 1 increases expression ISO Miconazole results in increased expression of GTF2F1 mRNA CTD PMID:27462272 NCBI chr 9:10,032,806...10,042,392
Ensembl chr 9:10,033,011...10,042,418
JBrowse link
G H2ax H2A.X variant histone increases expression ISO Miconazole results in increased expression of H2AX mRNA CTD PMID:27462272 NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981
JBrowse link
G Hdac6 histone deacetylase 6 increases expression EXP Miconazole results in increased expression of HDAC6 mRNA CTD PMID:22262564 NCBI chr  X:15,295,372...15,316,673
Ensembl chr  X:15,295,473...15,316,671
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha decreases expression EXP Miconazole results in decreased expression of HIF1A mRNA CTD PMID:22262564 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hmgb2 high mobility group box 2 increases expression ISO Miconazole results in increased expression of HMGB2 mRNA CTD PMID:27462272 NCBI chr16:36,077,615...36,080,191
Ensembl chr16:36,077,617...36,080,191
Ensembl chr11:36,077,617...36,080,191
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase increases expression ISO Miconazole results in increased expression of HMGCR mRNA CTD PMID:27462272 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 increases expression ISO Miconazole results in increased expression of HMGCS1 mRNA CTD PMID:27462272 NCBI chr 2:52,427,351...52,445,082
Ensembl chr 2:52,431,601...52,445,055
JBrowse link
G Hmgn1 high mobility group nucleosome binding domain 1 increases expression ISO Miconazole results in increased expression of HMGN1 mRNA CTD PMID:27462272 NCBI chr11:36,474,028...36,479,947
Ensembl chr11:36,474,840...36,479,868
JBrowse link
G Hmox2 heme oxygenase 2 decreases expression EXP Miconazole results in decreased expression of HMOX2 mRNA CTD PMID:22262564 NCBI chr10:10,990,034...11,035,493
Ensembl chr10:10,990,034...11,035,484
JBrowse link
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 decreases expression ISO Miconazole results in decreased expression of HNRNPA2B1 mRNA CTD PMID:27462272 NCBI chr 4:81,237,496...81,241,281
Ensembl chr 4:81,237,496...81,241,282
JBrowse link
G Hook3 hook microtubule-tethering protein 3 decreases expression ISO Miconazole results in decreased expression of HOOK3 mRNA CTD PMID:27462272 NCBI chr16:70,710,347...70,818,789 JBrowse link
G Hsbp1 heat shock factor binding protein 1 increases expression ISO Miconazole results in increased expression of HSBP1 mRNA CTD PMID:27462272 NCBI chr19:51,985,196...51,989,528
Ensembl chr19:51,985,170...51,989,544
JBrowse link
G Hsd17b7 hydroxysteroid (17-beta) dehydrogenase 7 increases expression ISO Miconazole results in increased expression of HSD17B7 mRNA CTD PMID:27462272 NCBI chr13:88,288,116...88,308,019
Ensembl chr13:88,288,046...88,307,988
JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 increases expression ISO Miconazole results in increased expression of HSP90AB1 mRNA CTD PMID:27462272 NCBI chr 9:17,817,791...17,823,163
Ensembl chr 9:17,817,721...17,823,243
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 decreases expression EXP Miconazole results in decreased expression of HSPD1 mRNA CTD PMID:22262564 NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956
JBrowse link
G Hspg2 heparan sulfate proteoglycan 2 decreases expression ISO Miconazole results in decreased expression of HSPG2 mRNA CTD PMID:27462272 NCBI chr 5:155,812,096...155,913,751 JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 increases expression ISO Miconazole results in increased expression of IDI1 mRNA CTD PMID:27462272 NCBI chr17:57,976,266...57,984,036
Ensembl chr17:57,976,268...57,984,036
JBrowse link
G Ids iduronate 2-sulfatase decreases expression ISO Miconazole results in decreased expression of IDS mRNA CTD PMID:27462272 NCBI chr 8:69,447,971...69,466,708
Ensembl chr 8:69,449,801...69,466,618
JBrowse link
G Ifitm2 interferon induced transmembrane protein 2 increases expression ISO Miconazole results in increased expression of IFITM2 mRNA CTD PMID:27462272 NCBI chr 1:213,750,219...213,751,399
Ensembl chr 1:213,750,192...213,751,405
JBrowse link
G Igip IgA-inducing protein decreases expression ISO Miconazole results in decreased expression of IGIP mRNA CTD PMID:27462272 NCBI chr18:29,115,051...29,125,681
Ensembl chr18:29,124,428...29,124,589
JBrowse link
G Il4 interleukin 4 multiple interactions
decreases secretion
decreases expression
ISO 1-Methyl-3-isobutylxanthine inhibits the reaction [Miconazole results in decreased expression of IL4 mRNA]; 1-Methyl-3-isobutylxanthine inhibits the reaction [Miconazole results in decreased secretion of IL4 protein]; Bucladesine inhibits the reaction [Miconazole results in decreased expression of IL4 mRNA]; Bucladesine inhibits the reaction [Miconazole results in decreased secretion of IL4 protein]; Colforsin inhibits the reaction [Miconazole results in decreased expression of IL4 mRNA]; Colforsin inhibits the reaction [Miconazole results in decreased secretion of IL4 protein] CTD PMID:11886533, PMID:15284827 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il5 interleukin 5 multiple interactions
decreases expression
decreases secretion
ISO 1-Methyl-3-isobutylxanthine inhibits the reaction [Miconazole results in decreased expression of IL5 mRNA]; 1-Methyl-3-isobutylxanthine inhibits the reaction [Miconazole results in decreased secretion of IL5 protein]; Bucladesine inhibits the reaction [Miconazole results in decreased expression of IL5 mRNA]; Bucladesine inhibits the reaction [Miconazole results in decreased secretion of IL5 protein]; Colforsin inhibits the reaction [Miconazole results in decreased expression of IL5 mRNA]; Colforsin inhibits the reaction [Miconazole results in decreased secretion of IL5 protein] CTD PMID:11886533, PMID:15284827 NCBI chr10:39,066,716...39,069,587
Ensembl chr10:39,066,716...39,069,587
JBrowse link
G Impdh2 inosine monophosphate dehydrogenase 2 increases expression ISO Miconazole results in increased expression of IMPDH2 mRNA CTD PMID:27462272 NCBI chr 8:117,346,983...117,351,619
Ensembl chr 8:117,347,029...117,351,610
JBrowse link
G Insig1 insulin induced gene 1 increases expression ISO Miconazole results in increased expression of INSIG1 mRNA CTD PMID:27462272 NCBI chr 4:342,302...350,515
Ensembl chr 4:342,302...350,515
JBrowse link
G Insr insulin receptor decreases expression EXP Miconazole results in decreased expression of INSR mRNA CTD PMID:22262564 NCBI chr12:1,682,527...1,816,414
Ensembl chr12:1,680,957...1,816,414
JBrowse link
G Ints6l integrator complex subunit 6 like decreases expression ISO Miconazole results in decreased expression of INTS6L mRNA CTD PMID:27462272 NCBI chr  X:158,835,334...158,887,055
Ensembl chr  X:158,835,811...158,886,220
JBrowse link
G Ipo5 importin 5 increases expression ISO Miconazole results in increased expression of IPO5 mRNA CTD PMID:27462272 NCBI chr15:106,243,110...106,293,326
Ensembl chr15:106,257,650...106,292,112
JBrowse link
G Ireb2 iron responsive element binding protein 2 decreases expression ISO Miconazole results in decreased expression of IREB2 mRNA CTD PMID:27462272 NCBI chr 8:59,450,974...59,503,634
Ensembl chr 8:59,420,123...59,501,118
JBrowse link
G Jpt2 Jupiter microtubule associated homolog 2 increases expression ISO Miconazole results in increased expression of JPT2 mRNA CTD PMID:27462272 NCBI chr10:14,304,108...14,324,170
Ensembl chr10:14,304,104...14,324,211
JBrowse link
G Jrkl JRK-like decreases expression ISO Miconazole results in decreased expression of JRKL mRNA CTD PMID:27462272 NCBI chr 8:11,884,903...11,887,799
Ensembl chr 8:11,884,903...11,887,799
JBrowse link
G Kcnd2 potassium voltage-gated channel subfamily D member 2 decreases expression ISO Miconazole results in decreased expression of KCND2 mRNA CTD PMID:27462272 NCBI chr 4:48,309,283...48,816,804 JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Miconazole results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
G Khdrbs1 KH RNA binding domain containing, signal transduction associated 1 decreases expression ISO Miconazole results in decreased expression of KHDRBS1 mRNA CTD PMID:27462272 NCBI chr 5:147,927,145...147,953,093
Ensembl chr 5:147,927,152...147,953,093
JBrowse link
G Khsrp KH-type splicing regulatory protein decreases expression ISO Miconazole results in decreased expression of KHSRP mRNA CTD PMID:27462272 NCBI chr 9:10,013,795...10,023,670
Ensembl chr 9:10,013,854...10,022,924
JBrowse link
G Kif5b kinesin family member 5B decreases expression ISO Miconazole results in decreased expression of KIF5B mRNA CTD PMID:27462272 NCBI chr17:54,181,416...54,219,048
Ensembl chr17:54,181,419...54,212,096
JBrowse link
G Klhl24 kelch-like family member 24 decreases expression ISO Miconazole results in decreased expression of KLHL24 mRNA CTD PMID:27462272 NCBI chr11:84,613,101...84,643,674
Ensembl chr11:84,615,760...84,633,504
JBrowse link
G Kmt2d lysine methyltransferase 2D decreases expression ISO Miconazole results in decreased expression of KMT2D mRNA CTD PMID:27462272 NCBI chr 7:140,507,137...140,542,479
Ensembl chr 7:140,489,492...140,546,908
JBrowse link
G Kptn kaptin (actin binding protein) increases expression ISO Miconazole results in increased expression of KPTN mRNA CTD PMID:27462272 NCBI chr 1:78,015,714...78,016,508
Ensembl chr 1:78,015,722...78,023,676
JBrowse link
G Lamb1 laminin subunit beta 1 increases expression ISO Miconazole results in increased expression of LAMB1 mRNA CTD PMID:27462272 NCBI chr 6:50,528,796...50,596,593
Ensembl chr 6:50,528,823...50,596,079
JBrowse link
G Lars2 leucyl-tRNA synthetase 2, mitochondrial decreases expression ISO Miconazole results in decreased expression of LARS2 mRNA CTD PMID:27462272 NCBI chr 8:132,441,277...132,537,176
Ensembl chr 8:132,441,285...132,536,369
JBrowse link
G Lasp1 LIM and SH3 protein 1 increases expression ISO Miconazole results in increased expression of LASP1 mRNA CTD PMID:27462272 NCBI chr10:85,744,662...85,785,130
Ensembl chr10:85,744,568...85,785,133
JBrowse link
G Leng8 leukocyte receptor cluster member 8 decreases expression ISO Miconazole results in decreased expression of LENG8 mRNA CTD PMID:27462272 NCBI chr 1:73,722,088...73,734,459
Ensembl chr 1:73,722,088...73,733,788
JBrowse link
G Lig1 DNA ligase 1 decreases expression EXP Miconazole results in decreased expression of LIG1 mRNA CTD PMID:22262564