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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:imidazole antifungal drug
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Accession:CHEBI:87069 term browser browse the term
Definition:Any imidazole antifungal agent that has been used for the treatment of fungal infections in humans or animals.
Synonyms:related_synonym: imidazole antifungal drugs



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bifonazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases activity ISO bifonazole results in decreased activity of CYP19A1 protein CTD PMID:15554355 PMID:24496634 NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases activity ISO bifonazole results in decreased activity of CYP3A4 protein CTD PMID:15135088 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp51 cytochrome P450, family 51 decreases activity ISO bifonazole results in decreased activity of CYP51A1 protein CTD PMID:16989930 NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410
JBrowse link
butoconazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO butoconazole results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity ISO butoconazole results in increased activity of NR1I2 protein CTD PMID:25455453 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
climbazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression EXP climbazole results in increased expression of CYP2B1 mRNA; climbazole results in increased expression of CYP2B1 protein CTD PMID:11552297 PMID:11824557 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression EXP climbazole results in increased expression of CYP3A2 protein CTD PMID:11552297 PMID:11824557 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 increases expression EXP climbazole results in increased expression of CYP4A1 protein CTD PMID:11552297 NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464
JBrowse link
clotrimazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions
decreases activity
ISO Clotrimazole inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
Clotrimazole results in decreased activity of ABCB11 protein
CTD PMID:24014644 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A affects binding
multiple interactions
increases expression
ISO Clotrimazole binds to ABCB1 protein
Clotrimazole inhibits the reaction [ABCB1A protein results in increased secretion of fluorexon]
Clotrimazole results in increased expression of ABCB1 protein
Clotrimazole inhibits the reaction [ABCB1 protein results in increased export of Doxorubicin]; Clotrimazole inhibits the reaction [ABCB1 protein results in increased secretion of fluorexon]; Clotrimazole inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]
CTD PMID:8632764 PMID:8917702 PMID:12235267 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 increases expression ISO Clotrimazole results in increased expression of ABCC2 mRNA; Clotrimazole results in increased expression of ABCC2 protein CTD PMID:11836020 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 multiple interactions
increases expression
ISO MAPK14 promotes the reaction [Clotrimazole results in increased expression of ABCC3 mRNA]; SB 203580 inhibits the reaction [Clotrimazole results in increased expression of ABCC3 mRNA] CTD PMID:27507784 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
JBrowse link
G Acp2 acid phosphatase 2, lysosomal increases expression EXP Clotrimazole results in increased expression of ACP2 mRNA CTD PMID:30047161 NCBI chr 3:77,175,022...77,185,180
Ensembl chr 3:77,175,895...77,185,680
JBrowse link
G Adam22 ADAM metallopeptidase domain 22 decreases expression EXP Clotrimazole results in decreased expression of ADAM22 mRNA CTD PMID:30047161 NCBI chr 4:25,716,055...25,970,932
Ensembl chr 4:25,715,990...25,964,962
JBrowse link
G Adamts12 ADAM metallopeptidase with thrombospondin type 1 motif, 12 decreases expression EXP Clotrimazole results in decreased expression of ADAMTS12 mRNA CTD PMID:30047161 NCBI chr 2:60,032,873...60,327,629
Ensembl chr 2:60,032,873...60,327,629
JBrowse link
G Adamts7 ADAM metallopeptidase with thrombospondin type 1 motif, 7 increases expression EXP Clotrimazole results in increased expression of ADAMTS7 mRNA CTD PMID:30047161 NCBI chr 8:90,704,727...90,744,333
Ensembl chr 8:90,704,727...90,744,328
JBrowse link
G Adamtsl5 ADAMTS-like 5 decreases expression EXP Clotrimazole results in decreased expression of ADAMTSL5 mRNA CTD PMID:30047161 NCBI chr 7:9,362,623...9,371,248
Ensembl chr 7:9,363,237...9,370,285
JBrowse link
G Adar adenosine deaminase, RNA-specific decreases expression EXP Clotrimazole results in decreased expression of ADAR mRNA CTD PMID:30047161 NCBI chr 2:175,138,391...175,178,280
Ensembl chr 2:175,138,403...175,178,282
JBrowse link
G Adcy9 adenylate cyclase 9 decreases activity ISO Clotrimazole results in decreased activity of ADCY9 protein CTD PMID:30607468 NCBI chr10:11,138,966...11,262,067
Ensembl chr10:11,139,446...11,262,066
JBrowse link
G Adora2a adenosine A2a receptor increases expression EXP Clotrimazole results in increased expression of ADORA2A mRNA CTD PMID:30047161 NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386
JBrowse link
G Aebp1 AE binding protein 1 increases expression EXP Clotrimazole results in increased expression of AEBP1 mRNA CTD PMID:30047161 NCBI chr14:80,738,800...80,748,878
Ensembl chr14:80,738,892...80,748,877
JBrowse link
G Agfg1 ArfGAP with FG repeats 1 increases expression EXP Clotrimazole results in increased expression of AGFG1 mRNA CTD PMID:30047161 NCBI chr 9:84,124,845...84,182,615
Ensembl chr 9:84,125,120...84,178,128
JBrowse link
G Ahr aryl hydrocarbon receptor increases activity ISO Clotrimazole results in increased activity of AHR protein CTD PMID:26187274 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Ak6 adenylate kinase 6 increases expression EXP Clotrimazole results in increased expression of AK6 mRNA CTD PMID:30047161 NCBI chr 2:31,794,316...31,806,375
Ensembl chr 2:31,794,519...31,806,371
Ensembl chr20:31,794,519...31,806,371
JBrowse link
G Aldh9a1 aldehyde dehydrogenase 9 family, member A1 increases expression EXP Clotrimazole results in increased expression of ALDH9A1 mRNA CTD PMID:30047161 NCBI chr13:79,505,738...79,522,539
Ensembl chr13:79,505,695...79,540,568
JBrowse link
G Aldob aldolase, fructose-bisphosphate B affects localization ISO Clotrimazole affects the localization of ALDOB protein CTD PMID:12126931 NCBI chr 5:63,889,045...63,902,086
Ensembl chr 5:63,889,046...63,902,116
JBrowse link
G Ankrd40 ankyrin repeat domain 40 increases expression EXP Clotrimazole results in increased expression of ANKRD40 mRNA CTD PMID:30047161 NCBI chr10:79,282,075...79,295,322
Ensembl chr10:79,282,075...79,295,320
JBrowse link
G Apoe apolipoprotein E decreases expression EXP Clotrimazole results in decreased expression of APOE mRNA CTD PMID:30047161 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Arrdc1 arrestin domain containing 1 decreases expression EXP Clotrimazole results in decreased expression of ARRDC1 mRNA CTD PMID:30047161 NCBI chr 3:7,735,002...7,742,195
Ensembl chr 3:7,735,011...7,742,197
JBrowse link
G Atf3 activating transcription factor 3 increases expression
multiple interactions
ISO Clotrimazole results in increased expression of ATF3 mRNA
SB 203580 inhibits the reaction [Clotrimazole results in increased expression of ATF3 mRNA]
CTD PMID:27507784 PMID:27965148 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
JBrowse link
G Atp5f1c ATP synthase F1 subunit gamma increases expression EXP Clotrimazole results in increased expression of ATP5F1C mRNA CTD PMID:30047161 NCBI chr17:68,423,927...68,446,169
Ensembl chr17:68,423,909...68,608,367
JBrowse link
G Atp5pb ATP synthase peripheral stalk-membrane subunit b increases expression EXP Clotrimazole results in increased expression of ATP5F1 mRNA CTD PMID:30047161 NCBI chr 2:193,424,138...193,435,418
Ensembl chr 2:193,424,047...193,435,418
JBrowse link
G Atp5pd ATP synthase peripheral stalk subunit d increases expression EXP Clotrimazole results in increased expression of ATP5PD mRNA CTD PMID:30047161 NCBI chr10:100,657,700...100,662,960
Ensembl chr10:100,657,708...100,663,479
JBrowse link
G Atpaf2 ATP synthase mitochondrial F1 complex assembly factor 2 increases expression EXP Clotrimazole results in increased expression of ATPAF2 mRNA CTD PMID:30047161 NCBI chr10:45,205,658...45,221,891
Ensembl chr10:45,197,441...45,221,026
JBrowse link
G Atrip ATR interacting protein decreases expression EXP Clotrimazole results in decreased expression of ATRIP mRNA CTD PMID:30047161 NCBI chr 8:109,708,440...109,722,511
Ensembl chr 8:109,708,440...109,722,477
JBrowse link
G Azi2 5-azacytidine induced 2 increases expression EXP Clotrimazole results in increased expression of AZI2 mRNA CTD PMID:30047161 NCBI chr 8:117,773,248...117,797,844
Ensembl chr 8:117,773,279...117,797,847
JBrowse link
G Batf3 basic leucine zipper ATF-like transcription factor 3 increases expression EXP Clotrimazole results in increased expression of BATF3 mRNA CTD PMID:30047161 NCBI chr13:102,689,657...102,701,241
Ensembl chr13:102,689,657...102,701,139
JBrowse link
G Bbs4 Bardet-Biedl syndrome 4 decreases expression EXP Clotrimazole results in decreased expression of BBS4 mRNA CTD PMID:30047161 NCBI chr 8:59,731,912...59,765,408
Ensembl chr 8:59,731,912...59,765,607
JBrowse link
G Bckdha branched chain keto acid dehydrogenase E1 subunit alpha decreases expression EXP Clotrimazole results in decreased expression of BCKDHA mRNA CTD PMID:30047161 NCBI chr 1:81,138,946...81,167,765
Ensembl chr 1:81,138,947...81,167,862
JBrowse link
G Bhlhe22 basic helix-loop-helix family, member e22 decreases expression EXP Clotrimazole results in decreased expression of BHLHE22 mRNA CTD PMID:30047161 NCBI chr 2:100,486,400...100,489,510
Ensembl chr 2:100,486,400...100,489,510
JBrowse link
G Bicd2 BICD cargo adaptor 2 increases expression EXP Clotrimazole results in increased expression of BICD2 mRNA CTD PMID:30047161 NCBI chr17:15,259,773...15,304,889
Ensembl chr17:15,259,773...15,304,889
JBrowse link
G Bri3bp Bri3 binding protein increases expression EXP Clotrimazole results in increased expression of BRI3BP mRNA CTD PMID:30047161 NCBI chr12:31,176,742...31,188,563
Ensembl chr12:31,173,971...31,188,572
JBrowse link
G Btf3 basic transcription factor 3 decreases expression EXP Clotrimazole results in decreased expression of BTF3 mRNA CTD PMID:30047161 NCBI chr 2:29,659,764...29,666,898
Ensembl chr 2:29,659,231...29,666,879
JBrowse link
G C1qtnf1 C1q and TNF related 1 decreases expression EXP Clotrimazole results in decreased expression of C1QTNF1 mRNA CTD PMID:30047161 NCBI chr10:103,660,319...103,681,662
Ensembl chr10:103,660,327...103,681,660
JBrowse link
G C1qtnf5 C1q and TNF related 5 increases expression EXP Clotrimazole results in increased expression of C1QTNF5 mRNA CTD PMID:30047161 NCBI chr 8:44,450,934...44,453,075
Ensembl chr 8:44,451,154...44,453,074
JBrowse link
G Cacnb1 calcium voltage-gated channel auxiliary subunit beta 1 decreases expression EXP Clotrimazole results in decreased expression of CACNB1 mRNA CTD PMID:30047161 NCBI chr10:82,998,182...83,018,838
Ensembl chr10:82,998,182...83,018,694
JBrowse link
G Calr calreticulin increases expression EXP Clotrimazole results in increased expression of CALR mRNA CTD PMID:30047161 NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414
JBrowse link
G Casp12 caspase 12 decreases expression EXP Clotrimazole results in decreased expression of CASP12 mRNA CTD PMID:30047161 NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037
JBrowse link
G Casp3 caspase 3 multiple interactions ISO Clotrimazole inhibits the reaction [Benzo(a)pyrene results in increased expression of CASP3 mRNA]
[S-allylcysteine co-treated with Clotrimazole] inhibits the reaction [lead acetate results in increased activity of CASP3 protein]; Clotrimazole inhibits the reaction [lead acetate results in increased activity of CASP3 protein]
CTD PMID:22033380 PMID:24239969 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 multiple interactions ISO [S-allylcysteine co-treated with Clotrimazole] inhibits the reaction [lead acetate results in increased activity of CASP8 protein]; Clotrimazole inhibits the reaction [lead acetate results in increased activity of CASP8 protein] CTD PMID:22033380 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Cat catalase multiple interactions ISO [S-allylcysteine co-treated with Clotrimazole] inhibits the reaction [lead acetate results in decreased activity of CAT protein]; Clotrimazole inhibits the reaction [lead acetate results in decreased activity of CAT protein] CTD PMID:22033380 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccdc17 coiled-coil domain containing 17 decreases expression EXP Clotrimazole results in decreased expression of CCDC17 mRNA CTD PMID:30047161 NCBI chr 5:130,051,158...130,056,676
Ensembl chr 5:130,045,938...130,056,673
JBrowse link
G Ccdc28a coiled-coil domain containing 28A decreases expression EXP Clotrimazole results in decreased expression of CCDC28A mRNA CTD PMID:30047161 NCBI chr 1:12,857,668...12,872,944
Ensembl chr 1:12,857,666...12,873,003
JBrowse link
G Ccsap centriole, cilia and spindle-associated protein decreases expression EXP Clotrimazole results in decreased expression of CCSAP mRNA CTD PMID:30047161 NCBI chr19:51,824,954...51,843,469
Ensembl chr19:51,826,994...51,842,753
JBrowse link
G Cd81 Cd81 molecule increases expression EXP Clotrimazole results in increased expression of CD81 mRNA CTD PMID:30047161 NCBI chr 1:198,235,861...198,251,660
Ensembl chr 1:198,241,484...198,251,660
JBrowse link
G Cd93 CD93 molecule increases expression EXP Clotrimazole results in increased expression of CD93 mRNA CTD PMID:30047161 NCBI chr 3:135,891,859...135,898,378
Ensembl chr 3:135,891,859...135,898,378
JBrowse link
G Cdip1 cell death-inducing p53 target 1 decreases expression EXP Clotrimazole results in decreased expression of CDIP1 mRNA CTD PMID:30047161 NCBI chr10:10,773,538...10,796,979
Ensembl chr10:10,774,705...10,796,980
JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression ISO Clotrimazole results in decreased expression of CDK1 CTD PMID:20724915 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases expression ISO Clotrimazole results in decreased expression of CDK4 CTD PMID:20724915 NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A decreases expression ISO Clotrimazole results in decreased expression of CDKN1A CTD PMID:20724915 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression ISO Clotrimazole results in increased expression of CDKN1B CTD PMID:20724915 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Cdkn2aip CDKN2A interacting protein decreases expression EXP Clotrimazole results in decreased expression of CDKN2AIP mRNA CTD PMID:30047161 NCBI chr16:44,536,147...44,546,216
Ensembl chr16:44,536,234...44,540,033
JBrowse link
G Cenpj centromere protein J decreases expression EXP Clotrimazole results in decreased expression of CENPJ mRNA CTD PMID:30047161 NCBI chr15:30,627,206...30,690,384
Ensembl chr15:30,627,224...30,686,791
JBrowse link
G Chchd1 coiled-coil-helix-coiled-coil-helix domain containing 1 increases expression EXP Clotrimazole results in increased expression of CHCHD1 mRNA CTD PMID:30047161 NCBI chr15:3,592,719...3,593,901
Ensembl chr15:3,592,727...3,593,901
JBrowse link
G Chd2 chromodomain helicase DNA binding protein 2 decreases expression EXP Clotrimazole results in decreased expression of CHD2 mRNA CTD PMID:30047161 NCBI chr 1:127,188,146...127,317,041
Ensembl chr 1:127,190,059...127,300,502
JBrowse link
G Chst1 carbohydrate sulfotransferase 1 increases expression EXP Clotrimazole results in increased expression of CHST1 mRNA CTD PMID:30047161 NCBI chr 3:78,552,059...78,574,740
Ensembl chr 3:78,548,525...78,574,883
JBrowse link
G Cimap1c ciliary microtubule associated protein 1C increases expression EXP Clotrimazole results in increased expression of CIMAP1C mRNA CTD PMID:30047161 NCBI chr 8:57,248,746...57,281,084
Ensembl chr 8:57,248,746...57,281,004
JBrowse link
G Cisd2 CDGSH iron sulfur domain 2 increases expression EXP Clotrimazole results in increased expression of CISD2 mRNA CTD PMID:30047161 NCBI chr 2:223,828,937...223,853,768
Ensembl chr 2:223,828,937...223,868,946
JBrowse link
G Clcn3 chloride voltage-gated channel 3 increases expression EXP Clotrimazole results in increased expression of CLCN3 mRNA CTD PMID:30047161 NCBI chr16:29,127,152...29,200,133
Ensembl chr16:29,127,419...29,200,119
JBrowse link
G Clk2 CDC-like kinase 2 decreases expression EXP Clotrimazole results in decreased expression of CLK2 mRNA CTD PMID:30047161 NCBI chr 2:174,570,614...174,582,645
Ensembl chr 2:174,570,653...174,588,985
JBrowse link
G Cnn2 calponin 2 increases expression EXP Clotrimazole results in increased expression of CNN2 mRNA CTD PMID:30047161 NCBI chr 7:9,712,505...9,719,678
Ensembl chr 7:9,712,516...9,719,656
JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression EXP Clotrimazole results in decreased expression of COL1A1 mRNA CTD PMID:30047161 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Col6a2 collagen type VI alpha 2 chain increases expression EXP Clotrimazole results in increased expression of COL6A2 mRNA CTD PMID:30047161 NCBI chr20:12,021,676...12,049,425
Ensembl chr20:12,021,767...12,057,564
JBrowse link
G Col7a1 collagen type VII alpha 1 chain decreases expression EXP Clotrimazole results in decreased expression of COL7A1 mRNA CTD PMID:30047161 NCBI chr 8:109,604,877...109,637,249
Ensembl chr 8:109,604,861...109,637,252
JBrowse link
G Col9a2 collagen type IX alpha 2 chain decreases expression EXP Clotrimazole results in decreased expression of COL9A2 mRNA CTD PMID:30047161 NCBI chr 5:134,607,616...134,624,678
Ensembl chr 5:134,607,616...134,624,677
JBrowse link
G Commd2 COMM domain containing 2 increases expression EXP Clotrimazole results in increased expression of COMMD2 mRNA CTD PMID:30047161 NCBI chr 2:141,848,661...141,852,907
Ensembl chr 2:141,848,680...141,852,888
JBrowse link
G Coro2b coronin 2B increases expression EXP Clotrimazole results in increased expression of CORO2B mRNA CTD PMID:30047161 NCBI chr 8:62,906,861...63,017,295
Ensembl chr 8:62,906,867...63,017,302
JBrowse link
G Cox7a2 cytochrome c oxidase subunit 7A2 increases expression EXP Clotrimazole results in increased expression of COX7A2 mRNA CTD PMID:30047161 NCBI chr 8:80,716,824...80,720,922
Ensembl chr14:51,301,168...51,301,633
Ensembl chr 8:51,301,168...51,301,633
JBrowse link
G Cox8a cytochrome c oxidase subunit 8A increases expression EXP Clotrimazole results in increased expression of COX8A mRNA CTD PMID:30047161 NCBI chr 1:204,402,118...204,404,439 JBrowse link
G Cpz carboxypeptidase Z decreases expression EXP Clotrimazole results in decreased expression of CPZ mRNA CTD PMID:30047161 NCBI chr14:75,223,692...75,246,946
Ensembl chr14:75,223,605...75,246,945
JBrowse link
G Creb3l2 cAMP responsive element binding protein 3-like 2 increases expression EXP Clotrimazole results in increased expression of CREB3L2 mRNA CTD PMID:30047161 NCBI chr 4:65,907,570...66,112,078
Ensembl chr 4:65,907,655...66,023,763
JBrowse link
G Crisp1 cysteine-rich secretory protein 1 decreases expression EXP Clotrimazole results in decreased expression of CRISP1 mRNA CTD PMID:30047161 NCBI chr 9:20,741,775...20,768,796
Ensembl chr 9:20,741,777...20,768,796
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases activity ISO Clotrimazole results in decreased activity of CYP17A1 protein CTD PMID:31330226 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases activity ISO Clotrimazole results in decreased activity of CYP19A1 protein CTD PMID:15554355 NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression
decreases activity
EXP
ISO
Clotrimazole results in increased expression of CYP1A1 protein
Clotrimazole results in decreased activity of CYP1A1 protein
CTD PMID:7986207 PMID:33814510 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression
multiple interactions
EXP Clotrimazole results in increased expression of CYP1A2 protein
Clotrimazole inhibits the reaction [CYP1A2 protein results in increased metabolism of 3-cyano-7-ethoxycoumarin]
CTD PMID:7986207 PMID:19858067 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity ISO Clotrimazole results in decreased activity of CYP1B1 protein CTD PMID:33814510 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp2a2 cytochrome P450, family 2, subfamily a, polypeptide 2 multiple interactions EXP Clotrimazole inhibits the reaction [CYP2A2 protein results in increased metabolism of 7-benzyloxyquinoline] CTD PMID:19858067 NCBI chr 1:82,263,833...82,289,487
Ensembl chr 1:82,263,833...82,289,487
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 multiple interactions
increases activity
increases expression
EXP Clotrimazole inhibits the reaction [CYP2B1 protein results in increased metabolism of 7-benzyloxy-4-trifluoromethylcoumarin]
Clotrimazole results in increased activity of CYP2B1 protein
Clotrimazole results in increased expression of CYP2B1 mRNA; Clotrimazole results in increased expression of CYP2B1 protein
CTD PMID:1372805 PMID:7986207 PMID:19858067 PMID:36356836 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 increases expression EXP Clotrimazole results in increased expression of CYP2B2 mRNA; Clotrimazole results in increased expression of CYP2B2 protein CTD PMID:7986207 PMID:12971794 NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions
increases expression
increases activity
ISO Clotrimazole results in increased expression of and results in increased activity of CYP2B6 protein; Dexamethasone promotes the reaction [NR3C1 protein affects the reaction [NR1I2 protein promotes the reaction [Clotrimazole results in increased expression of CYP2B6 mRNA]]]; NR1I2 protein affects the reaction [Clotrimazole results in increased expression of and results in increased activity of CYP2B6 protein]; NR1I2 protein promotes the reaction [Clotrimazole results in increased expression of CYP2B6 mRNA]
NR1I3 protein affects the reaction [Clotrimazole results in increased expression of CYP2B10 mRNA]
Clotrimazole results in increased expression of CYP2B6 protein
Clotrimazole results in increased activity of CYP2B6 protein
CTD PMID:12049174 PMID:12571232 PMID:12695351 PMID:14977870 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 multiple interactions
decreases expression
EXP Clotrimazole inhibits the reaction [CYP2C11 protein results in increased metabolism of 7-methoxy-4-trifluoromethylcoumarin]
Clotrimazole results in decreased expression of CYP2C11 protein
CTD PMID:7986207 PMID:19858067 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066
JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 multiple interactions EXP Clotrimazole inhibits the reaction [CYP2C6V1 protein results in increased metabolism of 7-methoxy-4-trifluoromethylcoumarin] CTD PMID:19858067 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 decreases activity ISO Clotrimazole results in decreased activity of CYP2C8 protein CTD PMID:15601807 PMID:33775687
G Cyp2d2 cytochrome P450, family 2, subfamily d, polypeptide 2 multiple interactions EXP Clotrimazole inhibits the reaction [CYP2D2 protein results in increased metabolism of 3-(2-(N,N-diethyl-N-methylammonium)ethyl)-7-methoxy-4-methylcoumarin] CTD PMID:19858067 NCBI chr 7:113,935,138...113,939,209
Ensembl chr 7:113,935,138...113,939,209
JBrowse link
G Cyp2j3 cytochrome P450, family 2, subfamily j, polypeptide 3 decreases expression EXP Clotrimazole results in decreased expression of CYP2J3 mRNA CTD PMID:30047161 NCBI chr 5:111,219,921...111,244,987
Ensembl chr 5:111,178,703...111,244,794
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions
decreases activity
increases expression
increases activity
EXP
ISO
Clotrimazole inhibits the reaction [CYP3A2 protein results in increased metabolism of 7-benzyloxyquinoline]
Clotrimazole inhibits the reaction [CYP3A4 protein results in increased oxidation of 7-benzyloxy-4-trifluoromethylcoumarin]; Clotrimazole promotes the reaction [NR1I2 results in increased expression of CYP3A4 mRNA]; NR1I2 protein promotes the reaction [Clotrimazole results in increased expression of CYP3A4 mRNA]
Clotrimazole results in decreased activity of CYP3A4 protein
Clotrimazole results in increased expression of CYP3A4 mRNA; Clotrimazole results in increased expression of CYP3A4 protein
Clotrimazole results in increased activity of CYP3A4 protein
CTD PMID:8632764 PMID:12065438 PMID:12505310 PMID:12673034 PMID:14977870 More... NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 increases expression
multiple interactions
EXP Clotrimazole results in increased expression of CYP3A23-3A1 mRNA
Clotrimazole inhibits the reaction [CYP3A23-3A1 protein results in increased metabolism of 7-benzyloxyquinoline]
CTD PMID:12971794 PMID:16125621 PMID:19858067 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
Ensembl chr12:9,254,475...9,285,030
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 increases expression ISO Clotrimazole results in increased expression of CYP3A5 protein CTD PMID:8632764 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
JBrowse link
G Cyp51 cytochrome P450, family 51 decreases activity
decreases response to substance
ISO Clotrimazole results in decreased activity of CYP51A1 protein
CYP51A1 gene results in decreased susceptibility to Clotrimazole
CTD PMID:16989930 PMID:18694951 NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410
JBrowse link
G Dab2 DAB adaptor protein 2 increases expression EXP Clotrimazole results in increased expression of DAB2 mRNA CTD PMID:30047161 NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:55,514,700...55,567,476
JBrowse link
G Dbn1 drebrin 1 increases expression EXP Clotrimazole results in increased expression of DBN1 mRNA CTD PMID:30047161 NCBI chr17:9,150,608...9,164,982
Ensembl chr17:9,150,659...9,164,984
JBrowse link
G Dchs1 dachsous cadherin-related 1 increases expression EXP Clotrimazole results in increased expression of DCHS1 mRNA CTD PMID:30047161 NCBI chr 1:160,104,931...160,138,958
Ensembl chr 1:160,104,931...160,124,808
JBrowse link
G Dclk1 doublecortin-like kinase 1 decreases expression EXP Clotrimazole results in decreased expression of DCLK1 mRNA CTD PMID:30047161 NCBI chr 2:139,417,234...139,710,956
Ensembl chr 2:139,417,163...139,710,956
JBrowse link
G Ddx39a DExD-box helicase 39A increases expression EXP Clotrimazole results in increased expression of DDX39A mRNA CTD PMID:30047161 NCBI chr19:24,418,743...24,427,422
Ensembl chr19:24,418,114...24,426,954
JBrowse link
G Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 increases expression ISO Clotrimazole results in increased expression of DNAJB4 mRNA CTD PMID:27965148 NCBI chr 2:241,129,346...241,159,272
Ensembl chr 2:241,130,340...241,159,089
JBrowse link
G Doc2b double C2 domain beta increases expression EXP Clotrimazole results in increased expression of DOC2B mRNA CTD PMID:30047161 NCBI chr10:60,628,029...60,653,267
Ensembl chr10:60,628,029...60,653,267
JBrowse link
G Dok4 docking protein 4 increases expression EXP Clotrimazole results in increased expression of DOK4 mRNA CTD PMID:30047161 NCBI chr19:10,146,520...10,157,187
Ensembl chr19:10,146,474...10,158,203
JBrowse link
G Dph3 diphthamide biosynthesis 3 increases expression EXP Clotrimazole results in increased expression of DPH3 mRNA CTD PMID:30047161 NCBI chr16:7,288,295...7,293,734
Ensembl chr16:7,282,705...7,291,265
JBrowse link
G Dpm1 dolichyl-phosphate mannosyltransferase subunit 1, catalytic increases expression EXP Clotrimazole results in increased expression of DPM1 mRNA CTD PMID:30047161 NCBI chr 3:156,919,979...156,939,522
Ensembl chr 3:156,919,979...156,939,536
JBrowse link
G Dscam DS cell adhesion molecule decreases expression EXP Clotrimazole results in decreased expression of DSCAM mRNA CTD PMID:30047161 NCBI chr11:35,921,924...36,507,100
Ensembl chr11:35,926,896...36,507,415
JBrowse link
G Eid2 EP300 interacting inhibitor of differentiation 2 increases expression EXP Clotrimazole results in increased expression of EID2 mRNA CTD PMID:30047161 NCBI chr 1:83,538,274...83,539,599 JBrowse link
G Eif2a eukaryotic translation initiation factor 2A multiple interactions
increases phosphorylation
ISO [Clotrimazole results in increased phosphorylation of EIF2A protein] which results in increased expression of TMEFF2 protein CTD PMID:23405127 NCBI chr 2:142,761,303...142,794,767
Ensembl chr 2:142,761,416...142,795,068
JBrowse link
G Eng endoglin increases expression EXP Clotrimazole results in increased expression of ENG mRNA CTD PMID:30047161 NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230
JBrowse link
G Epb41l2 erythrocyte membrane protein band 4.1-like 2 increases expression EXP Clotrimazole results in increased expression of EPB41L2 mRNA CTD PMID:30047161 NCBI chr 1:19,863,010...20,037,795
Ensembl chr 1:19,863,009...20,037,721
JBrowse link
G Ephx1 epoxide hydrolase 1 increases activity EXP Clotrimazole results in increased activity of EPHX1 protein CTD PMID:1372805 NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235
JBrowse link
G Eps8l1 EPS8-like 1 decreases expression EXP Clotrimazole results in decreased expression of EPS8L1 mRNA CTD PMID:30047161 NCBI chr 1:69,343,202...69,359,778
Ensembl chr 1:69,344,243...69,363,524
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 decreases expression EXP Clotrimazole results in decreased expression of ERN1 mRNA CTD PMID:30047161 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
JBrowse link
G Esam endothelial cell adhesion molecule increases expression EXP Clotrimazole results in increased expression of ESAM mRNA CTD PMID:30047161 NCBI chr 8:37,238,228...37,249,217
Ensembl chr 8:37,238,287...37,249,215
JBrowse link
G F2rl1 F2R like trypsin receptor 1 multiple interactions ISO Clotrimazole inhibits the reaction [F2RL1 protein results in increased transport of Chlorides] CTD PMID:11804840 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226
JBrowse link
G Fam110b family with sequence similarity 110, member B decreases expression EXP Clotrimazole results in decreased expression of FAM110B mRNA CTD PMID:30047161 NCBI chr 5:18,789,362...18,929,647
Ensembl chr 5:18,789,389...18,929,828
JBrowse link
G Fam120b family with sequence similarity 120 member B increases expression EXP Clotrimazole results in increased expression of FAM120B mRNA CTD PMID:30047161 NCBI chr 1:56,320,015...56,385,064
Ensembl chr 1:56,339,129...56,385,061
JBrowse link
G Fam124a family with sequence similarity 124 member A decreases expression EXP Clotrimazole results in decreased expression of FAM124A mRNA CTD PMID:30047161 NCBI chr15:36,799,836...36,855,062
Ensembl chr15:36,799,877...36,853,683
JBrowse link
G Fam167b family with sequence similarity 167, member B increases expression EXP Clotrimazole results in increased expression of FAM167B mRNA CTD PMID:30047161 NCBI chr 5:141,920,695...141,922,342
Ensembl chr 5:141,920,695...141,922,340
JBrowse link
G Fanci FA complementation group I increases expression EXP Clotrimazole results in increased expression of FANCI mRNA CTD PMID:30047161 NCBI chr 1:133,327,264...133,383,661
Ensembl chr 1:133,327,297...133,383,640
JBrowse link
G Fas Fas cell surface death receptor multiple interactions ISO [S-allylcysteine co-treated with Clotrimazole] inhibits the reaction [lead acetate affects the localization of and results in increased activity of FAS protein] CTD PMID:22033380 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Fhl2 four and a half LIM domains 2 increases expression EXP Clotrimazole results in increased expression of FHL2 mRNA CTD PMID:30047161 NCBI chr 9:45,388,979...45,462,421
Ensembl chr 9:45,388,981...45,431,192
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit decreases expression ISO Clotrimazole results in decreased expression of FOS protein CTD PMID:10223459 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Fstl1 follistatin-like 1 increases expression EXP Clotrimazole results in increased expression of FSTL1 mRNA CTD PMID:30047161 NCBI chr11:62,895,391...62,948,581
Ensembl chr11:62,779,783...62,948,677
JBrowse link
G Fxyd5 FXYD domain-containing ion transport regulator 5 increases expression EXP Clotrimazole results in increased expression of FXYD5 mRNA CTD PMID:30047161 NCBI chr 1:86,267,937...86,277,329
Ensembl chr 1:86,267,406...86,277,519
JBrowse link
G Galr2 galanin receptor 2 decreases expression EXP Clotrimazole results in decreased expression of GALR2 mRNA CTD PMID:30047161 NCBI chr10:101,513,689...101,517,176
Ensembl chr10:101,514,471...101,517,176
JBrowse link
G Ganc glucosidase, alpha; neutral C decreases expression EXP Clotrimazole results in decreased expression of GANC mRNA CTD PMID:30047161 NCBI chr 3:107,353,369...107,406,104
Ensembl chr 3:107,353,369...107,405,241
JBrowse link
G Gap43 growth associated protein 43 decreases expression EXP Clotrimazole results in decreased expression of GAP43 mRNA CTD PMID:30047161 NCBI chr11:58,376,371...58,470,047
Ensembl chr11:58,376,371...58,470,045
JBrowse link
G Garin5a golgi associated RAB2 interactor 5A decreases expression EXP Clotrimazole results in decreased expression of FAM71E1 mRNA CTD PMID:30047161 NCBI chr 1:94,988,959...94,995,971
Ensembl chr 1:94,988,613...94,993,539
JBrowse link
G Gemin7l1 gem (nuclear organelle) associated protein 7-like 1 increases expression EXP Clotrimazole results in increased expression of GEMIN7L1 mRNA CTD PMID:30047161 NCBI chr 4:78,269,910...78,270,681
Ensembl chr 4:78,269,888...78,270,669
JBrowse link
G Gfap glial fibrillary acidic protein increases expression ISO Clotrimazole results in increased expression of GFAP protein CTD PMID:10223459 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
JBrowse link
G Gldn gliomedin decreases expression EXP Clotrimazole results in decreased expression of GLDN mRNA CTD PMID:30047161 NCBI chr 8:54,679,015...54,723,198
Ensembl chr 8:54,679,119...54,723,196
JBrowse link
G Glrx2 glutaredoxin 2 increases expression EXP Clotrimazole results in increased expression of GLRX2 mRNA CTD PMID:30047161 NCBI chr13:55,481,875...55,504,737
Ensembl chr13:55,482,694...55,492,831
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 multiple interactions ISO [S-allylcysteine co-treated with Clotrimazole] inhibits the reaction [lead acetate results in increased expression of GOT1 protein] CTD PMID:22033380 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
JBrowse link
G Gpc3 glypican 3 decreases expression EXP Clotrimazole results in decreased expression of GPC3 mRNA CTD PMID:30047161 NCBI chr  X:131,868,986...132,236,824
Ensembl chr  X:131,868,990...132,236,798
JBrowse link
G Gpr62 G protein-coupled receptor 62 decreases expression EXP Clotrimazole results in decreased expression of GPR62 mRNA CTD PMID:30047161 NCBI chr 8:107,103,225...107,105,311
Ensembl chr 8:107,103,980...107,105,056
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO [S-allylcysteine co-treated with Clotrimazole] inhibits the reaction [lead acetate results in increased expression of GPT protein] CTD PMID:22033380 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Gramd1a GRAM domain containing 1A decreases expression EXP Clotrimazole results in decreased expression of GRAMD1A mRNA CTD PMID:30047161 NCBI chr 1:86,367,001...86,393,348
Ensembl chr 1:86,367,001...86,393,336
JBrowse link
G Grina glutamate ionotropic receptor NMDA type subunit associated protein 1 increases expression EXP Clotrimazole results in increased expression of GRINA mRNA CTD PMID:30047161 NCBI chr 7:107,962,194...107,965,372
Ensembl chr 7:107,962,207...107,965,366
JBrowse link
G Gse1 Gse1 coiled-coil protein decreases expression EXP Clotrimazole results in decreased expression of GSE1 mRNA CTD PMID:30047161 NCBI chr19:48,274,164...48,629,456
Ensembl chr19:48,274,127...48,629,458
JBrowse link
G Gsta2 glutathione S-transferase alpha 2 increases expression EXP Clotrimazole results in increased expression of GSTA2 mRNA CTD PMID:12971794 NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798
JBrowse link
G Gstm2 glutathione S-transferase mu 2 decreases expression EXP Clotrimazole results in decreased expression of GSTM2 mRNA CTD PMID:30047161 NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961
JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO Clotrimazole inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] CTD PMID:23769903 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Guca1a guanylate cyclase activator 1A increases expression EXP Clotrimazole results in increased expression of GUCA1A mRNA CTD PMID:30047161 NCBI chr 9:13,588,988...13,598,566
Ensembl chr 9:13,588,525...13,598,565
JBrowse link
G Gucy1a1 guanylate cyclase 1 soluble subunit alpha 1 increases expression EXP Clotrimazole results in increased expression of GUCY1A3 mRNA CTD PMID:30047161 NCBI chr 2:167,418,615...167,482,293
Ensembl chr 2:167,418,640...167,481,671
JBrowse link
G Herc1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 decreases expression EXP Clotrimazole results in decreased expression of HERC1 mRNA CTD PMID:30047161 NCBI chr 8:66,857,169...67,070,318
Ensembl chr 8:66,856,935...67,070,312
JBrowse link
G Hip1 huntingtin interacting protein 1 increases expression EXP Clotrimazole results in increased expression of HIP1 mRNA CTD PMID:30047161 NCBI chr12:21,133,364...21,267,796
Ensembl chr12:21,133,406...21,267,725
JBrowse link
G Hist1h2bd histone cluster 1 H2B family member D increases expression EXP Clotrimazole results in increased expression of HIST1H2BD mRNA CTD PMID:30047161 NCBI chr17:42,792,887...42,793,268 JBrowse link
G Hk2 hexokinase 2 affects localization
decreases expression
ISO Clotrimazole affects the localization of HK2 protein
Clotrimazole results in decreased expression of HK2 mRNA
CTD PMID:20724915 PMID:25863232 NCBI chr 4:115,234,509...115,283,530
Ensembl chr 4:115,234,509...115,283,530
JBrowse link
G Hmgb1 high mobility group box 1 increases expression EXP Clotrimazole results in increased expression of HMGB1 mRNA CTD PMID:30047161 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565
JBrowse link
G Hps4 HPS4, biogenesis of lysosomal organelles complex 3 subunit 2 decreases expression EXP Clotrimazole results in decreased expression of HPS4 mRNA CTD PMID:30047161 NCBI chr12:44,264,037...44,294,791
Ensembl chr12:44,264,037...44,294,632
JBrowse link
G Hsf1 heat shock transcription factor 1 increases activity ISO Clotrimazole results in increased activity of HSF1 protein CTD PMID:34170685 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011
JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 increases expression EXP Clotrimazole results in increased expression of HSPA4 mRNA CTD PMID:30047161 NCBI chr10:37,408,025...37,449,080
Ensembl chr10:37,408,025...37,449,001
JBrowse link
G Hspe1 heat shock protein family E (Hsp10) member 1 increases expression EXP Clotrimazole results in increased expression of HSPE1 mRNA CTD PMID:30047161 NCBI chr 9:56,589,912...56,593,000
Ensembl chr 9:56,589,789...56,593,089
JBrowse link
G Ifi44 interferon-induced protein 44 decreases expression EXP Clotrimazole results in decreased expression of IFI44 mRNA CTD PMID:30047161 NCBI chr 2:240,626,058...240,643,879
Ensembl chr 2:240,626,066...240,643,844
JBrowse link
G Ifnar2 interferon alpha and beta receptor subunit 2 decreases expression EXP Clotrimazole results in decreased expression of IFNAR2 mRNA CTD PMID:30047161 NCBI chr11:30,613,576...30,645,958
Ensembl chr11:30,613,767...30,668,124
JBrowse link
G Igf2bp2 insulin-like growth factor 2 mRNA binding protein 2 increases expression EXP Clotrimazole results in increased expression of IGF2BP2 mRNA CTD PMID:30047161 NCBI chr11:78,874,402...78,974,392
Ensembl chr11:78,874,414...78,974,377
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 increases expression
increases secretion
ISO Clotrimazole results in increased expression of IGFBP1 mRNA
Clotrimazole results in increased secretion of IGFBP1 protein
CTD PMID:12659874 NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482
JBrowse link
G Igsf10 immunoglobulin superfamily, member 10 decreases expression EXP Clotrimazole results in decreased expression of IGSF10 mRNA CTD PMID:30047161 NCBI chr 2:143,575,710...143,605,044
Ensembl chr 2:143,576,070...143,604,773
JBrowse link
G Il34 interleukin 34 increases expression EXP Clotrimazole results in increased expression of IL34 mRNA CTD PMID:30047161 NCBI chr19:38,714,990...38,782,749
Ensembl chr19:38,714,991...38,764,000
JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D increases expression EXP Clotrimazole results in increased expression of INPP5D mRNA CTD PMID:30047161 NCBI chr 9:88,287,680...88,392,748
Ensembl chr 9:88,287,677...88,392,746
JBrowse link
G Ints14 integrator complex subunit 14 increases expression EXP Clotrimazole results in increased expression of VWA9 mRNA CTD PMID:30047161 NCBI chr 8:65,475,788...65,500,807
Ensembl chr 8:65,475,910...65,500,804
JBrowse link
G Ip6k2 inositol hexakisphosphate kinase 2 decreases expression EXP Clotrimazole results in decreased expression of IP6K2 mRNA CTD PMID:30047161 NCBI chr 8:109,483,843...109,510,172
Ensembl chr 8:109,484,310...109,510,166
JBrowse link
G Itga9 integrin subunit alpha 9 increases expression EXP Clotrimazole results in increased expression of ITGA9 mRNA CTD PMID:30047161 NCBI chr 8:118,307,424...118,615,527
Ensembl chr 8:118,307,381...118,613,754
JBrowse link
G Itgb1 integrin subunit beta 1 increases expression EXP Clotrimazole results in increased expression of ITGB1 mRNA CTD PMID:30047161 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
JBrowse link
G Itih3 inter-alpha trypsin inhibitor, heavy chain 3 increases expression EXP Clotrimazole results in increased expression of ITIH3 mRNA CTD PMID:30047161 NCBI chr16:6,101,922...6,117,154
Ensembl chr16:6,101,930...6,116,924
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Clotrimazole results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
JBrowse link
G Kcnj1 potassium inwardly-rectifying channel, subfamily J, member 1 decreases expression EXP Clotrimazole results in decreased expression of KCNJ1 mRNA CTD PMID:30047161 NCBI chr 8:30,779,883...30,808,607
Ensembl chr 8:30,753,617...30,813,796
JBrowse link
G Kcnn4 potassium calcium-activated channel subfamily N member 4 multiple interactions
decreases activity
ISO Clotrimazole inhibits the reaction [[Ionomycin co-treated with Tetraethylammonium] results in increased activity of KCNN4 protein]
[S-allylcysteine co-treated with Clotrimazole] inhibits the reaction [lead acetate results in increased activity of KCNN4 protein]; Clotrimazole inhibits the reaction [lead acetate results in increased activity of KCNN4 protein]
Clotrimazole results in decreased activity of KCNN4 protein
CTD PMID:14985237 PMID:15921678 PMID:17699636 PMID:20050851 PMID:22033380 NCBI chr 1:79,956,380...79,974,354
Ensembl chr 1:79,959,322...79,974,340
JBrowse link
G Kdm4a lysine demethylase 4A decreases expression EXP Clotrimazole results in decreased expression of KDM4A mRNA CTD PMID:30047161 NCBI chr 5:131,672,754...131,719,534
Ensembl chr 5:131,672,754...131,719,501
JBrowse link
G Lcat lecithin cholesterol acyltransferase decreases expression EXP Clotrimazole results in decreased expression of LCAT mRNA CTD PMID:30047161 NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231
JBrowse link
G Lhfpl5 LHFPL tetraspan subfamily member 5 decreases expression EXP Clotrimazole results in decreased expression of LHFPL5 mRNA CTD PMID:30047161 NCBI chr20:6,632,324...6,642,534
Ensembl chr20:6,632,362...6,642,532
JBrowse link
G Lims2 LIM zinc finger domain containing 2 decreases expression EXP Clotrimazole results in decreased expression of LIMS2 mRNA CTD PMID:30047161 NCBI chr18:23,553,937...23,592,137
Ensembl chr18:23,553,937...23,592,137
JBrowse link
G Lipg lipase G, endothelial type decreases expression EXP Clotrimazole results in decreased expression of LIPG mRNA CTD PMID:30047161 NCBI chr18:68,514,923...68,536,105
Ensembl chr18:68,514,923...68,536,260
JBrowse link
G Loxl1 lysyl oxidase-like 1 increases expression EXP Clotrimazole results in increased expression of LOXL1 mRNA CTD PMID:30047161 NCBI chr 8:58,691,763...58,716,365
Ensembl chr 8:58,692,593...58,716,356
JBrowse link
G Lrp1 LDL receptor related protein 1 decreases expression EXP Clotrimazole results in decreased expression of LRP1 mRNA CTD PMID:30047161 NCBI chr 7:63,380,325...63,461,029
Ensembl chr 7:63,380,356...63,460,910
JBrowse link
G Lsamp limbic system-associated membrane protein decreases expression EXP Clotrimazole results in decreased expression of LSAMP mRNA CTD PMID:30047161 NCBI chr11:58,547,533...60,717,328
Ensembl chr11:58,554,805...60,717,029
JBrowse link
G Ltbp4 latent transforming growth factor beta binding protein 4 decreases expression EXP Clotrimazole results in decreased expression of LTBP4 mRNA CTD PMID:30047161 NCBI chr 1:82,600,136...82,634,346
Ensembl chr 1:82,600,136...82,632,178
JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions ISO MAPK14 promotes the reaction [Clotrimazole results in increased expression of ABCC3 mRNA] CTD PMID:27507784 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
JBrowse link
G Mapt microtubule-associated protein tau decreases expression EXP Clotrimazole results in decreased expression of MAPT mRNA CTD PMID:30047161 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
JBrowse link
G Marcks myristoylated alanine rich protein kinase C substrate increases expression EXP Clotrimazole results in increased expression of MARCKS mRNA CTD PMID:30047161 NCBI chr20:40,685,315...40,691,012
Ensembl chr20:40,685,315...40,691,012
JBrowse link
G Mark3 microtubule affinity regulating kinase 3 increases expression EXP Clotrimazole results in increased expression of MARK3 mRNA CTD PMID:30047161 NCBI chr 6:130,626,612...130,716,245
Ensembl chr 6:130,627,482...130,716,647
JBrowse link
G Mbnl1 muscleblind-like splicing regulator 1 decreases expression EXP Clotrimazole results in decreased expression of MBNL1 mRNA CTD PMID:30047161 NCBI chr 2:144,639,819...144,814,395
Ensembl chr 2:144,670,285...144,814,368
JBrowse link
G Mcfd2 multiple coagulation factor deficiency 2, ER cargo receptor complex subunit increases expression EXP Clotrimazole results in increased expression of MCFD2 mRNA CTD PMID:30047161 NCBI chr 6:7,274,469...7,285,841
Ensembl chr 6:7,274,469...7,285,841
JBrowse link
G Mfap2 microfibril associated protein 2 decreases expression EXP Clotrimazole results in decreased expression of MFAP2 mRNA CTD PMID:30047161 NCBI chr 5:153,312,068...153,320,266
Ensembl chr 5:153,314,711...153,320,259
JBrowse link
G Mipol1 mirror-image polydactyly 1 decreases expression EXP Clotrimazole results in decreased expression of MIPOL1 mRNA CTD PMID:30047161 NCBI chr 6:74,755,293...75,090,403
Ensembl chr 6:74,755,395...75,086,811
JBrowse link
G Mir96 microRNA 96 increases expression EXP Clotrimazole results in increased expression of MIR96 mRNA CTD PMID:27427493 NCBI chr 4:58,788,411...58,788,516
Ensembl chr 4:58,788,411...58,788,516
JBrowse link
G Mllt3 MLLT3, super elongation complex subunit increases expression EXP Clotrimazole results in increased expression of MLLT3 mRNA CTD PMID:30047161 NCBI chr 5:102,259,075...102,515,447
Ensembl chr 5:102,260,011...102,515,361
JBrowse link
G Mturn maturin, neural progenitor differentiation regulator homolog decreases expression EXP Clotrimazole results in decreased expression of MTURN mRNA CTD PMID:30047161 NCBI chr 4:83,807,528...83,828,494
Ensembl chr 4:83,807,579...83,824,950
JBrowse link
G Mxra8 matrix remodeling associated 8 decreases expression EXP Clotrimazole results in decreased expression of MXRA8 mRNA CTD PMID:30047161 NCBI chr 5:166,448,919...166,453,645
Ensembl chr 5:166,449,154...166,453,636
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression ISO Clotrimazole results in decreased expression of MYC protein CTD PMID:10223459 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Myct1 myc target 1 increases expression EXP Clotrimazole results in increased expression of MYCT1 mRNA CTD PMID:30047161 NCBI chr 1:42,018,137...42,029,410
Ensembl chr 1:42,018,137...42,029,410
JBrowse link
G Myef2 myelin expression factor 2 increases expression EXP Clotrimazole results in increased expression of MYEF2 mRNA CTD PMID:30047161 NCBI chr 3:112,338,241...112,374,122
Ensembl chr 3:112,338,241...112,374,181
JBrowse link
G Myl9 myosin light chain 9 increases expression EXP Clotrimazole results in increased expression of MYL9 mRNA CTD PMID:30047161 NCBI chr 3:145,281,943...145,288,333
Ensembl chr 3:145,281,937...145,288,333
JBrowse link
G Myo16 myosin XVI increases expression EXP Clotrimazole results in increased expression of MYO16 mRNA CTD PMID:30047161 NCBI chr16:78,884,405...79,364,445
Ensembl chr16:78,884,406...79,248,388
JBrowse link
G Myo1b myosin Ib increases expression EXP Clotrimazole results in increased expression of MYO1B mRNA CTD PMID:30047161 NCBI chr 9:49,690,043...49,852,373
Ensembl chr 9:49,690,086...49,850,798
JBrowse link
G Naaladl2 N-acetylated alpha-linked acidic dipeptidase-like 2 decreases expression EXP Clotrimazole results in decreased expression of NAALADL2 mRNA CTD PMID:30047161 NCBI chr 2:106,639,146...107,992,218
Ensembl chr 2:106,645,608...107,991,689
JBrowse link
G Nacc2 NACC family member 2 decreases expression EXP Clotrimazole results in decreased expression of NACC2 mRNA CTD PMID:30047161 NCBI chr 3:8,879,952...8,946,660
Ensembl chr 3:8,883,065...8,946,660
JBrowse link
G Ncoa1 nuclear receptor coactivator 1 multiple interactions ISO Clotrimazole promotes the reaction [NR1I3 protein modified form binds to NCOA1 protein]
Clotrimazole promotes the reaction [NR1I2 protein binds to NCOA1 protein]; Clotrimazole promotes the reaction [NR1I3 protein modified form binds to NCOA1 protein]
CTD PMID:17998298 PMID:18973326 PMID:21924250 NCBI chr 6:27,232,609...27,507,992
Ensembl chr 6:27,232,611...27,475,664
JBrowse link
G Ncor1 nuclear receptor co-repressor 1 multiple interactions ISO Clotrimazole promotes the reaction [NR1I3 protein modified form binds to NCOR1 protein] CTD PMID:18973326 NCBI chr10:46,999,536...47,142,294
Ensembl chr10:46,999,536...47,141,032
JBrowse link
G Ndfip2 Nedd4 family interacting protein 2 increases expression EXP Clotrimazole results in increased expression of NDFIP2 mRNA CTD PMID:30047161 NCBI chr15:82,032,366...82,087,043
Ensembl chr15:82,032,366...82,086,317
JBrowse link
G Ndufa5 NADH:ubiquinone oxidoreductase subunit A5 increases expression EXP Clotrimazole results in increased expression of NDUFA5 mRNA CTD PMID:30047161 NCBI chr 4:52,997,327...53,005,685
Ensembl chr 4:52,995,546...53,005,598
JBrowse link
G Ndufaf7 NADH:ubiquinone oxidoreductase complex assembly factor 7 increases expression EXP Clotrimazole results in increased expression of NDUFAF7 mRNA CTD PMID:30047161 NCBI chr 6:16,108,630...16,119,810
Ensembl chr 6:16,103,003...16,119,810
JBrowse link
G Ndufb5 NADH:ubiquinone oxidoreductase subunit B5 increases expression EXP Clotrimazole results in increased expression of NDUFB5 mRNA CTD PMID:30047161 NCBI chr 2:115,519,248...115,533,589
Ensembl chr 2:115,519,154...115,533,589
JBrowse link
G Ndufs3 NADH:ubiquinone oxidoreductase core subunit S3 increases expression EXP Clotrimazole results in increased expression of NDUFS3 mRNA CTD PMID:30047161 NCBI chr 3:76,876,646...76,883,824
Ensembl chr 3:76,876,646...76,883,824
JBrowse link
G Ndufs6 NADH:ubiquinone oxidoreductase subunit S6 increases expression EXP Clotrimazole results in increased expression of NDUFS6 mRNA CTD PMID:30047161 NCBI chr 1:29,968,833...29,977,423
Ensembl chr 1:29,968,842...29,977,467
JBrowse link
G Nedd4 NEDD4 E3 ubiquitin protein ligase decreases expression EXP Clotrimazole results in decreased expression of NEDD4 mRNA CTD PMID:30047161 NCBI chr 8:73,384,095...73,468,951
Ensembl chr 8:73,383,695...73,468,951
JBrowse link
G Niban1 niban apoptosis regulator 1 increases expression EXP Clotrimazole results in increased expression of FAM129A mRNA CTD PMID:30047161 NCBI chr13:63,674,240...63,827,748
Ensembl chr13:63,674,171...63,827,729
JBrowse link
G Nid1 nidogen 1 increases expression EXP Clotrimazole results in increased expression of NID1 mRNA CTD PMID:30047161 NCBI chr17:86,085,133...86,158,272
Ensembl chr17:86,085,077...86,158,267
JBrowse link
G Nipsnap1 nipsnap homolog 1 decreases expression EXP Clotrimazole results in decreased expression of NIPSNAP1 mRNA CTD PMID:30047161 NCBI chr14:79,734,234...79,758,101
Ensembl chr14:79,734,209...79,758,098
JBrowse link
G Nipsnap3b nipsnap homolog 3B increases expression EXP Clotrimazole results in increased expression of NIPSNAP3B mRNA CTD PMID:30047161 NCBI chr 5:67,637,644...67,669,698
Ensembl chr 5:67,614,036...67,669,700
JBrowse link
G Nob1 NIN1 (RPN12) binding protein 1 homolog decreases expression EXP Clotrimazole results in decreased expression of NOB1 mRNA CTD PMID:30047161 NCBI chr19:35,322,803...35,335,354
Ensembl chr19:35,322,669...35,346,815
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions
increases activity
increases expression
ISO
EXP
Clotrimazole binds to and results in increased activity of NR1I2 protein; Clotrimazole promotes the reaction [NR1I2 protein binds to NCOA1 protein]; Clotrimazole promotes the reaction [NR1I2 results in increased expression of CYP3A4 mRNA]; Dexamethasone promotes the reaction [NR3C1 protein affects the reaction [NR1I2 protein promotes the reaction [Clotrimazole results in increased expression of CYP2B6 mRNA]]]; NR1I2 protein affects the reaction [Clotrimazole results in increased expression of and results in increased activity of CYP2B6 protein]; NR1I2 protein promotes the reaction [Clotrimazole results in increased expression of CYP2B6 mRNA]; NR1I2 protein promotes the reaction [Clotrimazole results in increased expression of CYP3A4 mRNA]
Clotrimazole results in increased activity of NR1I2 protein
Clotrimazole results in increased expression of NR1I2 mRNA
CTD PMID:12049174 PMID:12065438 PMID:12695351 PMID:14977870 PMID:15548381 More... NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions
decreases activity
increases activity
affects binding
ISO
EXP
1,1-bis(4-hydroxyphenyl)cyclohexane inhibits the reaction [Clotrimazole binds to NR1I3 protein]; 4,4'-hexafluorisopropylidene diphenol inhibits the reaction [Clotrimazole binds to NR1I3 protein]; androstan-3-ol inhibits the reaction [Clotrimazole binds to NR1I3 protein]; bisphenol A inhibits the reaction [Clotrimazole binds to NR1I3 protein]; bisphenol B inhibits the reaction [Clotrimazole binds to NR1I3 protein]; Clotrimazole binds to and affects the activity of NR1I3 protein; Clotrimazole binds to and results in decreased activity of NR1I3 protein; Clotrimazole binds to and results in increased activity of and results in increased localization of NR1I3 protein mutant form; Clotrimazole binds to and results in increased activity of NR1I3 protein alternative form; Clotrimazole inhibits the reaction [4-nonylphenol results in increased activity of NR1I3 protein]; Clotrimazole inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime binds to and results in increased activity of NR1I3 protein mutant form]; Clotrimazole promotes the reaction [NR1I3 protein modified form binds to NCOA1 protein]
Clotrimazole results in decreased activity of NR1I3 protein
Clotrimazole results in increased activity of NR1I3 protein; Clotrimazole results in increased activity of NR1I3 protein alternative form
Clotrimazole results in decreased activity of NR1I3 protein; Clotrimazole results in decreased activity of NR1I3 protein alternative form
Clotrimazole results in increased activity of NR1I3 protein; Clotrimazole results in increased activity of NR1I3 protein alternative form; Clotrimazole results in increased activity of NR1I3 protein mutant form
androstan-3-ol inhibits the reaction [Clotrimazole results in increased activity of NR1I3 protein mutant form]; Clotrimazole inhibits the reaction [androstan-3-ol results in decreased activity of NR1I3 protein alternative form]; Clotrimazole inhibits the reaction [Imidazoles results in decreased activity of NR1I3 protein alternative form]; Imidazoles inhibits the reaction [Clotrimazole results in increased activity of NR1I3 protein mutant form]
Clotrimazole results in increased activity of NR1I3 protein; Clotrimazole results in increased activity of NR1I3 protein mutant form
Clotrimazole promotes the reaction [NR1I3 protein modified form binds to NCOA1 protein]; Clotrimazole promotes the reaction [NR1I3 protein modified form binds to NCOR1 protein]; NR1I3 protein affects the reaction [Clotrimazole results in increased expression of CYP2B10 mRNA]
CTD PMID:12049174 PMID:15905360 PMID:16919048 PMID:18973326 PMID:20686338 More... NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions ISO Dexamethasone promotes the reaction [NR3C1 protein affects the reaction [NR1I2 protein promotes the reaction [Clotrimazole results in increased expression of CYP2B6 mRNA]]] CTD PMID:12695351 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
JBrowse link
G Nrcam neuronal cell adhesion molecule decreases expression EXP Clotrimazole results in decreased expression of NRCAM mRNA CTD PMID:30047161 NCBI chr 6:61,402,813...61,698,536
Ensembl chr 6:61,329,863...61,702,992
JBrowse link
G Nsfl1c NSFL1 cofactor increases expression EXP Clotrimazole results in increased expression of NSFL1C mRNA CTD PMID:30047161 NCBI chr 3:139,978,306...140,002,876
Ensembl chr 3:139,978,301...140,002,870
JBrowse link
G Nudcd2 NudC domain containing 2 increases expression EXP Clotrimazole results in increased expression of NUDCD2 mRNA CTD PMID:30047161 NCBI chr10:25,163,247...25,168,738
Ensembl chr10:25,163,220...25,168,738
JBrowse link
G Nudt12 nudix hydrolase 12 decreases expression EXP Clotrimazole results in decreased expression of NUDT12 mRNA CTD PMID:30047161 NCBI chr 9:98,741,627...98,755,039
Ensembl chr 9:98,742,360...98,755,039
JBrowse link
G Odc1 ornithine decarboxylase 1 increases expression EXP Clotrimazole results in increased expression of ODC1 mRNA CTD PMID:12971794 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
JBrowse link
G Optn optineurin increases expression EXP Clotrimazole results in increased expression of OPTN mRNA CTD PMID:30047161 NCBI chr17:73,209,572...73,260,251
Ensembl chr17:73,209,575...73,260,251
JBrowse link
G Orc1 origin recognition complex, subunit 1 increases expression EXP Clotrimazole results in increased expression of ORC1 mRNA CTD PMID:30047161 NCBI chr 5:123,324,273...123,348,375
Ensembl chr 5:123,324,315...123,348,375
JBrowse link
G P2rx3 purinergic receptor P2X 3 decreases expression EXP Clotrimazole results in decreased expression of P2RX3 mRNA CTD PMID:30047161 NCBI chr 3:70,080,850...70,124,664
Ensembl chr 3:70,080,851...70,125,178
JBrowse link
G Pcnx4 pecanex 4 decreases expression EXP Clotrimazole results in decreased expression of PCNXL4 mRNA CTD PMID:30047161 NCBI chr 6:91,125,063...91,170,423
Ensembl chr 6:91,125,063...91,170,439
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta increases expression EXP Clotrimazole results in increased expression of PDGFRB mRNA CTD PMID:30047161 NCBI chr18:54,499,962...54,538,840
Ensembl chr18:54,499,964...54,538,843
JBrowse link
G Pdhx pyruvate dehydrogenase complex, component X increases expression EXP Clotrimazole results in increased expression of PDHX mRNA CTD PMID:30047161 NCBI chr 3:89,372,248...89,431,779
Ensembl chr 3:89,371,497...89,431,773
JBrowse link
G Pdia4 protein disulfide isomerase family A, member 4 increases expression EXP Clotrimazole results in increased expression of PDIA4 mRNA CTD PMID:30047161 NCBI chr 4:76,803,198...76,822,245
Ensembl chr 4:76,803,198...76,822,107
JBrowse link
G Pex2 peroxisomal biogenesis factor 2 increases expression EXP Clotrimazole results in increased expression of PEX2 mRNA CTD PMID:30047161 NCBI chr 2:96,050,380...96,072,928
Ensembl chr 2:96,045,958...96,073,404
JBrowse link
G Pfkm phosphofructokinase, muscle decreases expression ISO Clotrimazole results in decreased expression of PFKM mRNA CTD PMID:25863232 NCBI chr 7:129,221,679...129,259,192
Ensembl chr 7:129,221,653...129,259,192
JBrowse link
G Pfkp phosphofructokinase, platelet affects localization ISO Clotrimazole affects the localization of PFKP protein CTD PMID:12126931 NCBI chr17:63,729,743...63,794,026
Ensembl chr17:63,729,780...63,794,018
JBrowse link
G Phf1 PHD finger protein 1 decreases expression EXP Clotrimazole results in decreased expression of PHF1 mRNA CTD PMID:30047161 NCBI chr20:5,017,765...5,022,872
Ensembl chr20:5,017,893...5,022,871
JBrowse link
G Pias1 protein inhibitor of activated STAT, 1 decreases expression EXP Clotrimazole results in decreased expression of PIAS1 mRNA CTD PMID:30047161 NCBI chr 8:63,338,150...63,451,670
Ensembl chr 8:63,338,150...63,438,905
JBrowse link
G Pink1 PTEN induced kinase 1 decreases expression EXP Clotrimazole results in decreased expression of PINK1 mRNA CTD PMID:30047161 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
JBrowse link
G Pla1a phospholipase A1 member A increases expression EXP Clotrimazole results in increased expression of PLA1A mRNA CTD PMID:30047161 NCBI chr11:62,320,112...62,357,779
Ensembl chr11:62,320,493...62,357,779
JBrowse link
G Plau plasminogen activator, urokinase decreases expression EXP Clotrimazole results in decreased expression of PLAU mRNA CTD PMID:30047161 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
JBrowse link
G Plch2 phospholipase C, eta 2 decreases expression EXP Clotrimazole results in decreased expression of PLCH2 mRNA CTD PMID:30047161 NCBI chr 5:165,544,209...165,613,769
Ensembl chr 5:165,544,200...165,602,356
JBrowse link
G Plekho1 pleckstrin homology domain containing O1 increases expression EXP Clotrimazole results in increased expression of PLEKHO1 mRNA CTD PMID:30047161 NCBI chr 2:183,544,487...183,552,928
Ensembl chr 2:183,544,499...183,552,785
JBrowse link
G Podxl podocalyxin-like increases expression EXP Clotrimazole results in increased expression of PODXL mRNA CTD PMID:30047161 NCBI chr 4:60,135,124...60,181,829
Ensembl chr 4:60,135,109...60,181,899
JBrowse link
G Pole3 DNA polymerase epsilon 3, accessory subunit increases expression EXP Clotrimazole results in increased expression of POLE3 mRNA CTD PMID:30047161 NCBI chr 5:75,973,941...75,977,175
Ensembl chr 5:75,974,717...75,977,231
Ensembl chr 7:75,974,717...75,977,231
JBrowse link
G Ppm1j protein phosphatase, Mg2+/Mn2+ dependent, 1J decreases expression EXP Clotrimazole results in decreased expression of PPM1J mRNA CTD PMID:30047161 NCBI chr 2:192,278,597...192,283,883
Ensembl chr 2:192,278,517...192,283,882
JBrowse link
G Ppp1r9a protein phosphatase 1, regulatory subunit 9A decreases expression EXP Clotrimazole results in decreased expression of PPP1R9A mRNA CTD PMID:30047161 NCBI chr 4:32,970,501...33,292,360
Ensembl chr 4:33,024,450...33,286,907
JBrowse link
G Prdx2 peroxiredoxin 2 multiple interactions ISO [S-allylcysteine co-treated with Clotrimazole] inhibits the reaction [lead acetate affects the localization of PRDX2 protein]; [S-allylcysteine co-treated with Clotrimazole] inhibits the reaction [lead acetate promotes the reaction [PRDX2 protein binds to PRDX2 protein]]; Clotrimazole inhibits the reaction [lead acetate promotes the reaction [PRDX2 protein binds to PRDX2 protein]] CTD PMID:22033380 NCBI chr19:23,180,927...23,186,217
Ensembl chr19:23,180,930...23,186,194
JBrowse link
G Prkch protein kinase C, eta increases expression EXP Clotrimazole results in increased expression of PRKCH mRNA CTD PMID:30047161 NCBI chr 6:92,292,000...92,490,663
Ensembl chr 6:92,292,000...92,490,654
JBrowse link
G Prkd2 protein kinase D2 decreases expression EXP Clotrimazole results in decreased expression of PRKD2 mRNA CTD PMID:30047161 NCBI chr 1:77,513,625...77,542,386
Ensembl chr 1:77,513,986...77,542,376
JBrowse link
G Prrx1 paired related homeobox 1 increases expression EXP Clotrimazole results in increased expression of PRRX1 mRNA CTD PMID:30047161 NCBI chr13:75,600,777...75,671,896
Ensembl chr13:75,601,706...75,670,866
JBrowse link
G Prss41 serine protease 41 decreases expression EXP Clotrimazole results in decreased expression of PRSS41 mRNA CTD PMID:30047161 NCBI chr10:12,865,872...12,873,552
Ensembl chr10:12,865,872...12,873,552
JBrowse link
G Psip1 PC4 and SRSF1 interacting protein 1 increases expression EXP Clotrimazole results in increased expression of PSIP1 mRNA CTD PMID:30047161 NCBI chr 5:97,847,010...97,879,280
Ensembl chr 5:97,847,015...97,879,257
JBrowse link
G Ptgfrn prostaglandin F2 receptor inhibitor increases expression EXP Clotrimazole results in increased expression of PTGFRN mRNA CTD PMID:30047161 NCBI chr 2:188,469,521...188,544,795
Ensembl chr 2:188,469,521...188,544,795
JBrowse link
G Rab11fip4 RAB11 family interacting protein 4 increases expression EXP Clotrimazole results in increased expression of RAB11FIP4 mRNA CTD PMID:30047161 NCBI chr10:64,550,109...64,658,123
Ensembl chr10:64,550,177...64,654,759
JBrowse link
G Rab9a RAB9A, member RAS oncogene family decreases expression EXP Clotrimazole results in decreased expression of RAB9A mRNA CTD PMID:30047161 NCBI chr  X:27,955,552...28,009,870
Ensembl chr  X:27,952,204...28,001,622
JBrowse link
G Rad18 RAD18 E3 ubiquitin protein ligase increases expression EXP Clotrimazole results in increased expression of RAD18 mRNA CTD PMID:30047161 NCBI chr 4:145,735,654...145,821,102
Ensembl chr 4:145,735,654...145,821,069
JBrowse link
G Ralbp1 ralA binding protein 1 decreases expression EXP Clotrimazole results in decreased expression of RALBP1 mRNA CTD PMID:30047161 NCBI chr 9:105,456,425...105,493,235
Ensembl chr 9:105,456,425...105,492,707
JBrowse link
G Rasip1 Ras interacting protein 1 increases expression EXP Clotrimazole results in increased expression of RASIP1 mRNA CTD PMID:30047161 NCBI chr 1:96,097,135...96,109,564
Ensembl chr 1:96,091,074...96,109,562
JBrowse link
G Rbp2 retinol binding protein 2 increases expression EXP Clotrimazole results in increased expression of RBP2 mRNA CTD PMID:30047161 NCBI chr 8:99,079,293...99,104,489
Ensembl chr 8:99,079,104...99,104,473
JBrowse link
G Rfc2 replication factor C subunit 2 increases expression EXP Clotrimazole results in increased expression of RFC2 mRNA CTD PMID:30047161 NCBI chr12:22,120,449...22,133,576
Ensembl chr12:22,120,010...22,133,557
JBrowse link
G Rftn2 raftlin family member 2 decreases expression EXP Clotrimazole results in decreased expression of RFTN2 mRNA CTD PMID:30047161 NCBI chr 9:56,651,617...56,707,830
Ensembl chr 9:56,630,460...56,707,810
JBrowse link
G Rgn regucalcin decreases expression EXP Clotrimazole results in decreased expression of RGN mRNA CTD PMID:12971794 NCBI chr  X:1,619,030...1,634,456
Ensembl chr  X:1,619,032...1,634,450
JBrowse link
G Rgs5 regulator of G-protein signaling 5 increases expression EXP Clotrimazole results in increased expression of RGS5 mRNA CTD PMID:30047161 NCBI chr13:81,848,254...81,885,053
Ensembl chr13:81,836,304...81,885,518
JBrowse link
G Rgs9bp regulator of G protein signaling 9 binding protein decreases expression EXP Clotrimazole results in decreased expression of RGS9BP mRNA CTD PMID:30047161 NCBI chr 1:88,249,438...88,250,151
Ensembl chr 1:88,249,438...88,250,151
JBrowse link
G Rilpl1 Rab interacting lysosomal protein-like 1 decreases expression EXP Clotrimazole results in decreased expression of RILPL1 mRNA CTD PMID:30047161 NCBI chr12:32,071,870...32,109,687
Ensembl chr12:32,071,693...32,109,938
JBrowse link
G Rnf8 ring finger protein 8 decreases expression EXP Clotrimazole results in decreased expression of RNF8 mRNA CTD PMID:30047161 NCBI chr20:7,682,258...7,710,448
Ensembl chr20:7,682,322...7,708,491
JBrowse link
G Rps27l ribosomal protein S27-like increases expression EXP Clotrimazole results in increased expression of RPS27L mRNA CTD PMID:30047161 NCBI chr 8:67,562,483...67,567,418
Ensembl chr 8:67,562,483...67,567,418
JBrowse link
G Rps6kb2 ribosomal protein S6 kinase B2 decreases expression EXP Clotrimazole results in decreased expression of RPS6KB2 mRNA CTD PMID:30047161 NCBI chr 1:201,451,265...201,458,096
Ensembl chr 1:201,451,265...201,458,078
JBrowse link
G Rsbn1 round spermatid basic protein 1 decreases expression EXP Clotrimazole results in decreased expression of RSBN1 mRNA CTD PMID:30047161 NCBI chr 2:191,416,631...191,470,711
Ensembl chr 2:191,416,631...191,470,711
JBrowse link
G Schip1 schwannomin interacting protein 1 increases expression EXP Clotrimazole results in increased expression of SCHIP1 mRNA CTD PMID:30047161 NCBI chr 2:152,127,171...152,888,587
Ensembl chr 2:152,126,953...152,888,585
JBrowse link
G Sdhd succinate dehydrogenase complex subunit D increases expression EXP Clotrimazole results in increased expression of SDHD mRNA CTD PMID:30047161 NCBI chr 8:50,944,702...50,954,298
Ensembl chr 8:50,944,704...50,954,238
JBrowse link
G Senp7 SUMO specific peptidase 7 decreases expression EXP Clotrimazole results in decreased expression of SENP7 mRNA CTD PMID:30047161 NCBI chr11:44,423,733...44,584,129
Ensembl chr11:44,423,735...44,564,711
JBrowse link
G Senp8 SUMO peptidase family member, NEDD8 specific decreases expression EXP Clotrimazole results in decreased expression of SENP8 mRNA CTD PMID:30047161 NCBI chr 8:60,135,446...60,148,836
Ensembl chr 8:60,121,714...60,148,928
JBrowse link
G Serpinf1 serpin family F member 1 decreases expression EXP Clotrimazole results in decreased expression of SERPINF1 mRNA CTD PMID:30047161 NCBI chr10:60,250,198...60,262,593
Ensembl chr10:60,249,708...60,262,646
JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 increases expression EXP Clotrimazole results in increased expression of SGK1 mRNA CTD PMID:30047161 NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283
JBrowse link
G Siglec1 sialic acid binding Ig like lectin 1 decreases expression EXP Clotrimazole results in decreased expression of SIGLEC1 mRNA CTD PMID:30047161 NCBI chr 3:118,287,988...118,307,125
Ensembl chr 3:118,287,988...118,306,850
JBrowse link
G Sipa1 signal-induced proliferation-associated 1 increases expression EXP Clotrimazole results in increased expression of SIPA1 mRNA CTD PMID:30047161 NCBI chr 1:202,938,532...202,950,672
Ensembl chr 1:202,938,580...202,950,591
JBrowse link
G Slc19a1 solute carrier family 19 member 1 multiple interactions
decreases activity
EXP Clotrimazole inhibits the reaction [SLC19A1 protein results in increased uptake of Methotrexate]
Clotrimazole results in decreased activity of SLC19A1 protein
CTD PMID:17482559 NCBI chr20:11,584,410...11,602,429
Ensembl chr20:11,584,411...11,601,972
JBrowse link
G Slc25a14 solute carrier family 25 member 14 decreases expression EXP Clotrimazole results in decreased expression of SLC25A14 mRNA CTD PMID:30047161 NCBI chr  X:127,807,630...127,845,823
Ensembl chr  X:127,807,449...127,845,823
JBrowse link
G Smpd1 sphingomyelin phosphodiesterase 1 multiple interactions ISO [S-allylcysteine co-treated with Clotrimazole] inhibits the reaction [lead acetate results in increased activity of SMPD1 protein]; Clotrimazole inhibits the reaction [lead acetate results in increased activity of SMPD1 protein] CTD PMID:22033380 NCBI chr 1:159,892,946...159,896,789
Ensembl chr 1:159,892,859...159,896,794
JBrowse link
G Snrnp27 small nuclear ribonucleoprotein U4/U6.U5 subunit 27 increases expression EXP Clotrimazole results in increased expression of SNRNP27 mRNA CTD PMID:30047161 NCBI chr 4:119,123,676...119,133,234
Ensembl chr 4:119,121,877...119,133,234
JBrowse link
G Snx16 sorting nexin 16 decreases expression EXP Clotrimazole results in decreased expression of SNX16 mRNA CTD PMID:30047161 NCBI chr 2:91,335,896...91,357,622
Ensembl chr 2:91,336,092...91,357,619
JBrowse link
G Snx24 sorting nexin 24 decreases expression EXP Clotrimazole results in decreased expression of SNX24 mRNA CTD PMID:30047161 NCBI chr18:46,670,987...46,826,070
Ensembl chr18:46,671,443...46,826,068
JBrowse link
G Snx33 sorting nexin 33 decreases expression EXP Clotrimazole results in decreased expression of SNX33 mRNA CTD PMID:30047161 NCBI chr 8:57,315,861...57,328,522
Ensembl chr 8:57,317,161...57,327,538
JBrowse link
G Sord sorbitol dehydrogenase increases expression EXP Clotrimazole results in increased expression of SORD mRNA CTD PMID:30047161 NCBI chr 3:109,184,697...109,216,133
Ensembl chr 3:109,184,676...109,216,133
JBrowse link
G Sptssa serine palmitoyltransferase, small subunit A increases expression EXP Clotrimazole results in increased expression of SPTSSA mRNA CTD PMID:30047161 NCBI chr 6:72,144,714...72,156,130
Ensembl chr 6:72,144,714...72,156,214
JBrowse link
G Srp9 signal recognition particle 9 increases expression EXP Clotrimazole results in increased expression of SRP9 mRNA CTD PMID:30047161 NCBI chr13:93,832,580...93,840,720
Ensembl chr13:93,832,580...93,840,720
JBrowse link
G Srpx sushi-repeat-containing protein, X-linked decreases expression EXP Clotrimazole results in decreased expression of SRPX mRNA CTD PMID:30047161 NCBI chr  X:12,676,984...12,751,296
Ensembl chr  X:12,566,645...12,747,882
JBrowse link
G Srpx2 sushi-repeat-containing protein, X-linked 2 increases expression EXP Clotrimazole results in increased expression of SRPX2 mRNA CTD PMID:30047161 NCBI chr  X:97,106,455...97,132,197
Ensembl chr  X:97,106,561...97,132,195
JBrowse link
G Sspn sarcospan decreases expression EXP Clotrimazole results in decreased expression of SSPN mRNA CTD PMID:30047161 NCBI chr 4:178,890,030...178,946,267
Ensembl chr 4:178,897,147...178,931,554
JBrowse link
G Stac SH3 and cysteine rich domain increases expression EXP Clotrimazole results in increased expression of STAC mRNA CTD PMID:30047161 NCBI chr 8:111,530,800...111,653,228
Ensembl chr 8:111,530,800...111,654,008
JBrowse link
G Ston1 stonin 1 decreases expression EXP Clotrimazole results in decreased expression of RAET1L mRNA CTD PMID:30047161 NCBI chr 6:5,843,186...5,892,557
Ensembl chr 6:5,843,185...5,892,449
JBrowse link
G Styxl1 serine/threonine/tyrosine interacting-like 1 decreases expression EXP Clotrimazole results in decreased expression of STYXL1 mRNA CTD PMID:30047161 NCBI chr12:20,907,410...20,940,232
Ensembl chr12:20,907,435...20,939,752
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 decreases expression EXP Clotrimazole results in decreased expression of SULT1A1 mRNA CTD PMID:9566755 NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562
JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 decreases expression EXP Clotrimazole results in decreased expression of SULT2A1 mRNA CTD PMID:9566755 NCBI chr 1:75,451,178...75,508,113
Ensembl chr 1:74,911,100...75,508,134
JBrowse link
G Surf1 SURF1, cytochrome c oxidase assembly factor decreases expression EXP Clotrimazole results in decreased expression of SURF1 mRNA CTD PMID:30047161 NCBI chr 3:10,241,793...10,244,686
Ensembl chr 3:10,241,837...10,263,315
JBrowse link
G Syne2 spectrin repeat containing nuclear envelope protein 2 decreases expression EXP Clotrimazole results in decreased expression of SYNE2 mRNA CTD PMID:30047161 NCBI chr 6:94,537,088...94,848,085
Ensembl chr 6:94,537,088...94,848,064
JBrowse link
G Tafazzin tafazzin, phospholipid-lysophospholipid transacylase increases expression EXP Clotrimazole results in increased expression of TAZ mRNA CTD PMID:30047161 NCBI chr  X:152,065,539...152,076,178
Ensembl chr  X:152,065,609...152,074,001
JBrowse link
G Tagln transgelin increases expression EXP Clotrimazole results in increased expression of TAGLN mRNA CTD PMID:30047161 NCBI chr 8:46,224,939...46,230,413
Ensembl chr 8:46,222,472...46,230,668
JBrowse link
G Tet3 tet methylcytosine dioxygenase 3 decreases expression EXP Clotrimazole results in decreased expression of TET3 mRNA CTD PMID:30047161 NCBI chr 4:115,867,412...115,964,433
Ensembl chr 4:115,871,265...115,964,193
JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression EXP Clotrimazole results in increased expression of TGFB1 mRNA CTD PMID:30047161 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tgfbi transforming growth factor, beta induced decreases expression EXP Clotrimazole results in decreased expression of TGFBI mRNA CTD PMID:30047161 NCBI chr17:7,955,603...7,984,903
Ensembl chr17:7,955,603...7,985,240
JBrowse link
G Thap3 THAP domain containing 3 decreases expression EXP Clotrimazole results in decreased expression of THAP3 mRNA CTD PMID:30047161 NCBI chr 5:162,488,480...162,494,149
Ensembl chr 5:162,488,480...162,494,149
JBrowse link
G Tmed4 transmembrane p24 trafficking protein 4 increases expression EXP Clotrimazole results in increased expression of TMED4 mRNA CTD PMID:30047161 NCBI chr14:81,125,049...81,129,646
Ensembl chr14:81,125,053...81,129,631
JBrowse link
G Tmed7 transmembrane p24 trafficking protein 7 increases expression EXP Clotrimazole results in increased expression of TMED7 mRNA CTD PMID:30047161 NCBI chr18:39,318,564...39,325,640
Ensembl chr18:39,297,351...39,325,640
JBrowse link
G Tmeff2 transmembrane protein with EGF-like and two follistatin-like domains 2 multiple interactions ISO [Clotrimazole results in increased phosphorylation of EIF2A protein] which results in increased expression of TMEFF2 protein CTD PMID:23405127 NCBI chr 9:50,445,947...50,733,473
Ensembl chr 9:50,436,079...50,733,475
JBrowse link
G Tmem116 transmembrane protein 116 decreases expression EXP Clotrimazole results in decreased expression of TMEM116 mRNA CTD PMID:30047161 NCBI chr12:35,021,912...35,089,409
Ensembl chr12:35,041,572...35,089,430
JBrowse link
G Tmem39b transmembrane protein 39b decreases expression EXP Clotrimazole results in decreased expression of TMEM39B mRNA CTD PMID:30047161 NCBI chr 5:142,024,271...142,046,607
Ensembl chr 5:142,024,273...142,046,549
JBrowse link
G Tmem88 transmembrane protein 88 increases expression EXP Clotrimazole results in increased expression of TMEM88 mRNA CTD PMID:30047161 NCBI chr10:54,118,752...54,120,447
Ensembl chr10:54,118,752...54,120,447
JBrowse link
G Tmem97 transmembrane protein 97 increases expression EXP Clotrimazole results in increased expression of TMEM97 mRNA CTD PMID:30047161 NCBI chr10:63,438,228...63,447,311
Ensembl chr10:63,438,222...63,589,730
JBrowse link
G Tmprss9 transmembrane serine protease 9 decreases expression EXP Clotrimazole results in decreased expression of TMPRSS9 mRNA CTD PMID:30047161 NCBI chr 7:8,810,321...8,831,177
Ensembl chr 7:8,810,320...8,831,177
JBrowse link
G Tnks1bp1 tankyrase 1 binding protein 1 increases expression EXP Clotrimazole results in increased expression of TNKS1BP1 mRNA CTD PMID:30047161 NCBI chr 3:70,135,335...70,160,071
Ensembl chr 3:70,137,837...70,160,038
JBrowse link
G Tnxa-ps1 tenascin XA, pseudogene 1 decreases expression EXP Clotrimazole results in decreased expression of TNXA-PS1 mRNA CTD PMID:30047161 NCBI chr20:4,026,471...4,027,826 JBrowse link
G Tp53 tumor protein p53 increases expression ISO Clotrimazole results in increased expression of TP53 protein CTD PMID:10223459 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tpm2 tropomyosin 2 increases expression EXP Clotrimazole results in increased expression of TPM2 mRNA CTD PMID:30047161 NCBI chr 5:57,770,919...57,780,278
Ensembl chr 5:57,770,864...57,779,992
JBrowse link
G Traf4 Tnf receptor associated factor 4 increases expression EXP Clotrimazole results in increased expression of TRAF4 mRNA CTD PMID:30047161 NCBI chr10:63,054,169...63,060,284
Ensembl chr10:63,054,181...63,060,284
JBrowse link
G Trpc6 transient receptor potential cation channel, subfamily C, member 6 increases expression EXP Clotrimazole results in increased expression of TRPC6 mRNA CTD PMID:30047161 NCBI chr 8:5,759,387...5,864,000
Ensembl chr 8:5,758,935...5,828,092
JBrowse link
G Trpm2 transient receptor potential cation channel, subfamily M, member 2 multiple interactions EXP
ISO
Clotrimazole inhibits the reaction [Adenosine Diphosphate Ribose promotes the reaction [TRPM2 protein results in increased transport of Calcium]]
[Clotrimazole results in decreased activity of TRPM2 protein] inhibits the reaction [Mustard Gas results in increased abundance of Calcium]
CTD PMID:21900507 PMID:22036725 NCBI chr20:10,703,568...10,753,189
Ensembl chr20:10,707,014...10,753,181
JBrowse link
G Tstd2 thiosulfate sulfurtransferase like domain containing 2 decreases expression EXP Clotrimazole results in decreased expression of TSTD2 mRNA CTD PMID:30047161 NCBI chr 5:60,371,751...60,415,916
Ensembl chr 5:60,393,454...60,415,916
JBrowse link
G Ttc33 tetratricopeptide repeat domain 33 decreases expression EXP Clotrimazole results in decreased expression of TTC33 mRNA CTD PMID:30047161 NCBI chr 2:54,279,906...54,326,851
Ensembl chr 2:54,279,997...54,323,871
JBrowse link
G Tubb2a tubulin, beta 2A class IIa increases expression EXP Clotrimazole results in increased expression of TUBB2A mRNA CTD PMID:30047161 NCBI chr17:30,796,842...30,800,713
Ensembl chr17:30,747,503...30,800,714
JBrowse link
G Txlna taxilin alpha increases expression EXP Clotrimazole results in increased expression of TXLNA mRNA CTD PMID:30047161 NCBI chr 5:141,969,337...141,985,054
Ensembl chr 5:141,969,346...141,984,583
JBrowse link
G U2surp U2 snRNP-associated SURP domain containing decreases expression EXP Clotrimazole results in decreased expression of U2SURP mRNA CTD PMID:30047161 NCBI chr 8:96,018,932...96,075,795
Ensembl chr 8:96,022,957...96,075,691
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 affects expression ISO Clotrimazole affects the expression of UGT1A1 mRNA CTD PMID:15849716 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Upf2 UPF2, regulator of nonsense mediated mRNA decay decreases expression EXP Clotrimazole results in decreased expression of UPF2 mRNA CTD PMID:30047161 NCBI chr17:72,224,575...72,335,896
Ensembl chr17:72,225,316...72,335,855
JBrowse link
G Uqcr10 ubiquinol-cytochrome c reductase, complex III subunit X increases expression EXP Clotrimazole results in increased expression of UQCR10 mRNA CTD PMID:30047161 NCBI chr14:79,566,151...79,569,017
Ensembl chr14:79,566,157...79,569,003
JBrowse link
G Vash2 vasohibin 2 increases expression EXP Clotrimazole results in increased expression of VASH2 mRNA CTD PMID:30047161 NCBI chr13:102,529,718...102,561,204
Ensembl chr13:102,529,719...102,560,391
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions
increases secretion
ISO [Clotrimazole co-treated with Imatinib Mesylate] results in increased secretion of VEGFA protein
Clotrimazole results in increased secretion of VEGFA protein
CTD PMID:25863232 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Wnt2 Wnt family member 2 decreases expression EXP Clotrimazole results in decreased expression of WNT2 mRNA CTD PMID:30047161 NCBI chr 4:46,328,408...46,374,673
Ensembl chr 4:46,333,998...46,374,402
JBrowse link
G Xpo4 exportin 4 decreases expression EXP Clotrimazole results in decreased expression of XPO4 mRNA CTD PMID:30047161 NCBI chr15:31,717,016...31,807,723
Ensembl chr15:31,716,762...31,807,908
JBrowse link
G Zbtb10 zinc finger and BTB domain containing 10 decreases expression EXP Clotrimazole results in decreased expression of ZBTB10 mRNA CTD PMID:30047161 NCBI chr 2:92,475,254...92,509,892
Ensembl chr 2:92,479,014...92,512,515
JBrowse link
G Zfp407 zinc finger protein 407 increases expression EXP Clotrimazole results in increased expression of ZFP407 mRNA CTD PMID:30047161 NCBI chr18:77,571,140...77,970,282
Ensembl chr18:77,571,204...77,974,129
JBrowse link
G Zscan2 zinc finger and SCAN domain containing 2 decreases expression EXP Clotrimazole results in decreased expression of ZSCAN2 mRNA CTD PMID:30047161 NCBI chr 1:134,833,701...134,848,957
Ensembl chr 1:134,833,871...134,848,952
JBrowse link
econazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy9 adenylate cyclase 9 increases activity ISO Econazole results in increased activity of ADCY9 protein CTD PMID:30607468 NCBI chr10:11,138,966...11,262,067
Ensembl chr10:11,139,446...11,262,066
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions
increases expression
decreases activity
ISO Econazole promotes the reaction [NR1I2 results in increased expression of CYP3A4 mRNA]; Econazole promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]
Econazole results in increased expression of CYP3A4 mRNA
Econazole results in decreased activity of CYP3A4 protein
CTD PMID:15135088 PMID:17998298 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp51 cytochrome P450, family 51 decreases response to substance ISO CYP51A1 gene results in decreased susceptibility to Econazole CTD PMID:18694951 NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410
JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO Econazole inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] CTD PMID:23769903 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Kcna3 potassium voltage-gated channel subfamily A member 3 multiple interactions
decreases activity
ISO [Econazole results in decreased activity of KCNA3 protein] which results in decreased import of Thallium CTD PMID:21362439 NCBI chr 2:194,632,106...194,634,059
Ensembl chr 2:194,632,196...194,650,138
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity
multiple interactions
ISO Econazole results in decreased activity of KCNH2 protein
[Econazole results in decreased activity of KCNH2 protein] which results in decreased import of Thallium
CTD PMID:21362439 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
JBrowse link
G Ncoa1 nuclear receptor coactivator 1 multiple interactions ISO Econazole promotes the reaction [NR1I2 protein binds to NCOA1 protein] CTD PMID:17998298 NCBI chr 6:27,232,609...27,507,992
Ensembl chr 6:27,232,611...27,475,664
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO Econazole binds to and results in increased activity of NR1I2 protein; Econazole promotes the reaction [NR1I2 protein binds to NCOA1 protein]; Econazole promotes the reaction [NR1I2 results in increased expression of CYP3A4 mRNA] CTD PMID:17998298 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 multiple interactions ISO [tebuconazole co-treated with Econazole] results in increased phosphorylation of PRKAA1 protein CTD PMID:30698772 NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978
JBrowse link
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 multiple interactions ISO [tebuconazole co-treated with Econazole] results in increased phosphorylation of PRKAA2 protein CTD PMID:30698772 NCBI chr 5:119,807,992...119,879,987
Ensembl chr 5:119,813,226...119,879,543
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Econazole inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
JBrowse link
G Trpm2 transient receptor potential cation channel, subfamily M, member 2 multiple interactions ISO [Econazole results in decreased activity of TRPM2 protein] inhibits the reaction [Mustard Gas results in increased abundance of Calcium] CTD PMID:22036725 NCBI chr20:10,703,568...10,753,189
Ensembl chr20:10,707,014...10,753,181
JBrowse link
G Ulk1 unc-51 like autophagy activating kinase 1 multiple interactions ISO [tebuconazole co-treated with Econazole] results in increased phosphorylation of ULK1 protein; dorsomorphin inhibits the reaction [[tebuconazole co-treated with Econazole] results in increased phosphorylation of ULK1 protein] CTD PMID:30698772 NCBI chr12:45,851,710...45,877,966
Ensembl chr12:45,851,710...45,877,966
JBrowse link
enilconazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 decreases expression ISO enilconazole results in decreased expression of ABCB11 mRNA CTD PMID:29451352 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 decreases expression ISO enilconazole results in decreased expression of ABCC2 mRNA CTD PMID:29451352 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 decreases expression
multiple interactions
increases expression
ISO
EXP
enilconazole results in decreased expression of ABCC3 mRNA
[enilconazole co-treated with clothianidin] results in increased expression of ABCC3 mRNA; [thiacloprid co-treated with enilconazole] results in increased expression of ABCC3 mRNA
enilconazole results in increased expression of ABCC3 mRNA
CTD PMID:29451352 PMID:33426623 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
JBrowse link
G Abcd3 ATP binding cassette subfamily D member 3 decreases expression ISO enilconazole results in decreased expression of ABCD3 mRNA CTD PMID:30853599 NCBI chr 2:209,852,087...209,905,763
Ensembl chr 2:209,852,087...209,906,020
JBrowse link
G Acox1 acyl-CoA oxidase 1 decreases expression ISO enilconazole results in decreased expression of ACOX1 mRNA CTD PMID:32201337 NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232
JBrowse link
G Adk adenosine kinase increases expression ISO enilconazole results in increased expression of ADK mRNA CTD PMID:32201337 NCBI chr15:2,863,241...3,246,453
Ensembl chr15:2,863,244...3,246,510
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 decreases expression
multiple interactions
increases expression
ISO
EXP
enilconazole results in decreased expression of ALDH1A1 mRNA
[thiacloprid co-treated with enilconazole] results in decreased expression of ALDH1A1 mRNA
enilconazole results in increased expression of ALDH1A1 mRNA
[enilconazole co-treated with clothianidin] results in increased expression of ALDH1A1 mRNA; [thiacloprid co-treated with enilconazole] results in increased expression of ALDH1A1 mRNA
CTD PMID:32201337 PMID:33426623 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member decreases expression
multiple interactions
ISO enilconazole results in decreased expression of ALDH2 mRNA
[Maneb co-treated with mancozeb co-treated with iprodione co-treated with enilconazole co-treated with Chlorpyrifos co-treated with Diazinon co-treated with Dimethoate] results in decreased expression of ALDH2 mRNA; [Maneb co-treated with mancozeb co-treated with iprodione co-treated with enilconazole co-treated with Chlorpyrifos co-treated with Diazinon co-treated with Dimethoate] results in decreased expression of and results in decreased activity of ALDH2 protein
CTD PMID:32201337 PMID:34830855 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521
JBrowse link
G Ano1 anoctamin 1 decreases expression ISO enilconazole results in decreased expression of ANO1 mRNA CTD PMID:29106682 NCBI chr 1:199,751,439...199,900,099
Ensembl chr 1:199,751,439...199,900,069
JBrowse link
G Anxa10 annexin A10 increases expression ISO enilconazole results in increased expression of ANXA10 mRNA CTD PMID:32194361 NCBI chr16:27,738,712...27,805,648
Ensembl chr16:27,738,712...27,805,648
JBrowse link
G Ar androgen receptor multiple interactions
affects binding
decreases expression
ISO Dihydrotestosterone inhibits the reaction [enilconazole results in increased activity of AR protein]; enilconazole inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; enilconazole inhibits the reaction [Dihydrotestosterone results in increased expression of AR mRNA]; enilconazole inhibits the reaction [Metribolone results in increased activity of AR protein]
enilconazole binds to AR protein
enilconazole results in decreased expression of AR mRNA
CTD PMID:15064155 PMID:18324785 PMID:21310686 PMID:30853599 PMID:33049310 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Arg1 arginase 1 decreases expression ISO enilconazole results in decreased expression of ARG1 mRNA CTD PMID:32194361 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422
JBrowse link
G Atp8b1 ATPase phospholipid transporting 8B1 increases expression ISO enilconazole results in increased expression of ATP8B1 mRNA CTD PMID:32201337 NCBI chr18:58,016,382...58,157,213
Ensembl chr18:58,018,268...58,157,396
JBrowse link
G Cat catalase increases expression ISO enilconazole results in increased expression of CAT mRNA CTD PMID:29451352 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases expression ISO enilconazole results in increased expression of CCL5 mRNA CTD PMID:32201337 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Ces2h carboxylesterase 2H multiple interactions
decreases expression
ISO [enilconazole co-treated with thiacloprid] results in increased expression of CES2 protein
enilconazole results in decreased expression of CES2 mRNA
CTD PMID:32201337 NCBI chr19:32,974,242...32,988,842
Ensembl chr19:32,974,242...32,988,830
JBrowse link
G Cftr CF transmembrane conductance regulator affects binding
decreases expression
ISO enilconazole binds to CFTR protein
enilconazole results in decreased expression of CFTR mRNA; enilconazole results in decreased expression of CFTR protein
CTD PMID:29106682 PMID:32814239 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756
JBrowse link
G Comt catechol-O-methyltransferase increases expression ISO enilconazole results in increased expression of COMT protein CTD PMID:32201337 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 affects expression ISO enilconazole affects the expression of CYP11A1 mRNA CTD PMID:30853599 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 increases expression ISO enilconazole results in increased expression of CYP17A1 mRNA CTD PMID:30853599 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases activity
affects secretion
ISO enilconazole results in decreased activity of CYP19A1 protein
enilconazole affects the secretion of CYP19A1 mRNA
CTD PMID:10806373 PMID:15554355 PMID:26141389 PMID:30853599 NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases activity
multiple interactions
increases expression
ISO enilconazole results in increased activity of CYP1A1 protein
enilconazole inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]
enilconazole results in increased expression of CYP1A1 mRNA; enilconazole results in increased expression of CYP1A1 protein
CTD PMID:19070657 PMID:21762035 PMID:32194361 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 affects expression
multiple interactions
ISO enilconazole affects the expression of CYP1A2 mRNA
[clothianidin co-treated with enilconazole] results in increased expression of CYP1A2 mRNA; [enilconazole co-treated with thiacloprid co-treated with clothianidin] results in increased expression of CYP1A2 mRNA; [thiacloprid co-treated with enilconazole] results in increased expression of CYP1A2 mRNA
CTD PMID:32201337 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression
multiple interactions
ISO enilconazole results in increased expression of CYP1B1 mRNA
[clothianidin co-treated with enilconazole] results in increased expression of CYP1B1 protein
CTD PMID:32201337 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 increases expression ISO enilconazole results in increased expression of CYP27A1 mRNA CTD PMID:32814239 NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 increases expression
multiple interactions
EXP enilconazole results in increased expression of CYP2B2 mRNA
[enilconazole co-treated with clothianidin] results in increased expression of CYP2B2 mRNA; [thiacloprid co-treated with enilconazole] results in increased expression of CYP2B2 mRNA
CTD PMID:33426623 NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions
increases expression
affects expression
ISO [enilconazole co-treated with thiacloprid] results in increased expression of CYP2B6 protein; [enilconazole co-treated with thiacloprid] results in increased expression of CYP2B9 protein; [thiacloprid co-treated with enilconazole] results in increased expression of CYP2B6 mRNA
enilconazole results in increased expression of CYP2B10
enilconazole affects the expression of CYP2B6 mRNA
CTD PMID:27853109 PMID:32201337 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 decreases expression ISO enilconazole results in decreased expression of CYP2C19 mRNA; enilconazole results in decreased expression of CYP2C19 protein CTD PMID:32194361 PMID:32201337 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions
decreases expression
ISO [clothianidin co-treated with enilconazole] results in decreased expression of CYP2E1 mRNA; [enilconazole co-treated with thiacloprid co-treated with clothianidin] results in decreased expression of CYP2E1 mRNA; [thiacloprid co-treated with enilconazole] results in decreased expression of CYP2E1 mRNA
enilconazole results in decreased expression of CYP2E1 mRNA
CTD PMID:32201337 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 affects expression
decreases activity
multiple interactions
increases expression
ISO enilconazole affects the expression of CYP3A4 mRNA
enilconazole results in decreased activity of CYP3A4 protein
[Amiodarone co-treated with Benzoic Acid co-treated with cyproconazole co-treated with flusilazole co-treated with enilconazole co-treated with prochloraz co-treated with propiconazole co-treated with tebuconazole] results in increased expression of CYP3A4 protein; [clothianidin co-treated with enilconazole] results in increased expression of CYP3A4 mRNA; [clothianidin co-treated with enilconazole] results in increased expression of CYP3A4 protein; [enilconazole co-treated with methidathion] results in increased expression of CYP3A4 mRNA; [enilconazole co-treated with thiacloprid co-treated with clothianidin] results in increased expression of CYP3A4 mRNA; [enilconazole co-treated with thiacloprid] results in increased expression of CYP3A4 protein; [thiacloprid co-treated with enilconazole] results in increased expression of CYP3A4 mRNA
enilconazole results in increased expression of CYP3A4 protein
CTD PMID:21762035 PMID:25028461 PMID:32201337 PMID:34273450 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 multiple interactions
increases expression
EXP [enilconazole co-treated with clothianidin] results in increased expression of CYP3A23-3A1 mRNA; [thiacloprid co-treated with enilconazole] results in increased expression of CYP3A23-3A1 mRNA
enilconazole results in increased expression of CYP3A23-3A1 mRNA
CTD PMID:33426623 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
Ensembl chr12:9,254,475...9,285,030
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 increases expression
multiple interactions
ISO enilconazole results in increased expression of CYP3A5 mRNA; enilconazole results in increased expression of CYP3A5 protein
[clothianidin co-treated with enilconazole] results in increased expression of CYP3A5 protein; [enilconazole co-treated with thiacloprid] results in increased expression of CYP3A5 protein
CTD PMID:32201337 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
JBrowse link
G Cyp51 cytochrome P450, family 51 decreases activity ISO enilconazole results in decreased activity of CYP51A1 protein CTD PMID:16989930 NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 decreases expression
multiple interactions
ISO
EXP
enilconazole results in decreased expression of CYP7A1 mRNA
[enilconazole co-treated with clothianidin] results in decreased expression of CYP7A1 mRNA; [thiacloprid co-treated with enilconazole] results in decreased expression of CYP7A1 mRNA
enilconazole results in decreased expression of CYP7A1 mRNA; enilconazole results in decreased expression of CYP7A1 protein
CTD PMID:29451352 PMID:32194361 PMID:32201337 PMID:32814239 PMID:33426623 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
JBrowse link
G Cyp7b1 cytochrome P450 family 7 subfamily B member 1 decreases expression ISO enilconazole results in decreased expression of CYP7B1 mRNA CTD PMID:32201337 NCBI chr 2:100,502,791...100,669,713
Ensembl chr 2:100,502,791...100,669,698
JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 increases expression ISO enilconazole results in increased expression of CYP8B1 mRNA CTD PMID:32814239 NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166
JBrowse link
G Dnm1 dynamin 1 decreases expression ISO enilconazole results in decreased expression of DNM1 mRNA CTD PMID:32201337 NCBI chr 3:15,604,782...15,648,654
Ensembl chr 3:15,604,784...15,648,538
JBrowse link
G Eln elastin decreases expression
multiple interactions
EXP enilconazole results in decreased expression of ELN mRNA
[enilconazole co-treated with clothianidin] results in decreased expression of ELN mRNA; [thiacloprid co-treated with enilconazole] results in decreased expression of ELN mRNA
CTD PMID:33426623 NCBI chr12:21,968,544...22,011,929
Ensembl chr12:21,968,544...22,011,928
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO enilconazole binds to and results in increased activity of ESR1 protein CTD PMID:33049310 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esr2 estrogen receptor 2 decreases expression
multiple interactions
ISO enilconazole results in decreased expression of ESR2 mRNA
enilconazole binds to and results in increased activity of ESR2 protein
CTD PMID:30853599 PMID:33049310 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G Fabp6 fatty acid binding protein 6 decreases expression ISO enilconazole results in decreased expression of FABP6 mRNA CTD PMID:32814239 NCBI chr10:28,063,603...28,068,276
Ensembl chr10:28,063,603...28,068,282
JBrowse link
G Fas Fas cell surface death receptor increases expression ISO enilconazole results in increased expression of FAS mRNA CTD PMID:32201337 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Fgf19 fibroblast growth factor 19 decreases expression
increases expression
ISO enilconazole results in decreased expression of FGF15 mRNA
enilconazole results in increased expression of FGF15 mRNA
CTD PMID:29451352 PMID:32814239 NCBI chr 1:200,056,526...200,060,980
Ensembl chr 1:200,056,644...200,060,287
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 decreases expression ISO enilconazole results in decreased expression of G6PC1 mRNA CTD PMID:32194361 PMID:32201337 NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804
JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression ISO enilconazole results in increased expression of GPX1 mRNA CTD PMID:29451352 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Gpx2 glutathione peroxidase 2 decreases expression ISO enilconazole results in decreased expression of GPX2 mRNA CTD PMID:29451352 NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877
JBrowse link
G Gsr glutathione-disulfide reductase increases expression ISO enilconazole results in increased expression of GSR mRNA CTD PMID:29451352 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Gss glutathione synthetase decreases expression ISO enilconazole results in decreased expression of GSS mRNA CTD PMID:29451352 NCBI chr 3:144,047,849...144,078,197
Ensembl chr 3:144,047,850...144,078,198
JBrowse link
G H2ax H2A.X variant histone multiple interactions ISO [Maneb co-treated with mancozeb co-treated with iprodione co-treated with enilconazole co-treated with Chlorpyrifos co-treated with Diazinon co-treated with Dimethoate] results in increased expression of H2AX protein CTD PMID:34830855 NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239
JBrowse link
G Haao 3-hydroxyanthranilate 3,4-dioxygenase decreases expression ISO enilconazole results in decreased expression of HAAO mRNA CTD PMID:32201337 NCBI chr 6:10,845,235...10,864,863
Ensembl chr 6:10,845,771...10,864,877
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase affects expression ISO enilconazole affects the expression of HMGCR mRNA CTD PMID:30853599 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 affects expression ISO enilconazole affects the expression of HMGCS1 mRNA CTD PMID:30853599 NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100
JBrowse link
G Hsd17b13 hydroxysteroid (17-beta) dehydrogenase 13 decreases expression ISO enilconazole results in decreased expression of HSD17B13 mRNA CTD PMID:30853599 NCBI chr14:5,751,697...5,766,809
Ensembl chr14:5,752,132...5,768,166
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 affects expression ISO enilconazole affects the expression of HSD3B1 mRNA CTD PMID:30853599 NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999
JBrowse link
G Ifng interferon gamma increases expression ISO enilconazole results in increased expression of IFNG mRNA CTD PMID:27393971 PMID:32814239 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il17a interleukin 17A multiple interactions
increases expression
ISO enilconazole inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA]
enilconazole results in increased expression of IL17A mRNA
CTD PMID:22289359 PMID:32814239 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
JBrowse link
G Il1a interleukin 1 alpha increases expression ISO enilconazole results in increased expression of IL1A mRNA CTD PMID:32814239 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta increases expression ISO enilconazole results in increased expression of IL1B mRNA CTD PMID:27393971 PMID:32814239 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 increases expression ISO enilconazole results in increased expression of IL6 mRNA CTD PMID:27393971 PMID:32201337 PMID:32814239 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression ISO enilconazole results in increased expression of JUN mRNA CTD PMID:32201337 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Khk ketohexokinase decreases expression ISO enilconazole results in decreased expression of KHK mRNA CTD PMID:32201337 NCBI chr 6:25,445,298...25,455,834
Ensembl chr 6:25,445,300...25,455,717
JBrowse link
G Klf4 KLF transcription factor 4 affects expression
decreases expression
ISO enilconazole affects the expression of KLF4 mRNA
enilconazole results in decreased expression of KLF4 mRNA
CTD PMID:29106682 PMID:32814239 NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602
JBrowse link
G Ky kyphoscoliosis peptidase multiple interactions
decreases expression
EXP [enilconazole co-treated with clothianidin] results in decreased expression of KY mRNA; [thiacloprid co-treated with enilconazole] results in decreased expression of KY mRNA
enilconazole results in decreased expression of KY mRNA
CTD PMID:33426623 NCBI chr 8:103,086,959...103,126,305
Ensembl chr 8:103,086,630...103,126,024
JBrowse link
G Lcn2 lipocalin 2 increases expression ISO enilconazole results in increased expression of LCN2 CTD PMID:27393971 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
JBrowse link
G Lhb luteinizing hormone subunit beta decreases expression EXP enilconazole results in decreased expression of LHB protein CTD PMID:36410587 NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972
JBrowse link
G Lpl lipoprotein lipase increases expression ISO enilconazole results in increased expression of LPL mRNA CTD PMID:32201337 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
JBrowse link
G Ly6d lymphocyte antigen 6 family member D decreases expression ISO enilconazole results in decreased expression of LY6D mRNA CTD PMID:32201337 NCBI chr 7:106,643,225...106,644,733
Ensembl chr 7:106,643,232...106,644,733
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases expression ISO enilconazole results in increased expression of MAPK8 mRNA CTD PMID:32201337 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Megf11 multiple EGF-like-domains 11 multiple interactions
decreases expression
EXP [enilconazole co-treated with clothianidin] results in decreased expression of MEGF11 mRNA; [thiacloprid co-treated with enilconazole] results in decreased expression of MEGF11 mRNA
enilconazole results in decreased expression of MEGF11 mRNA
CTD PMID:33426623 NCBI chr 8:64,892,312...65,218,984
Ensembl chr 8:64,892,387...65,216,061
JBrowse link
G Mep1b meprin A subunit beta affects expression
decreases expression
ISO enilconazole affects the expression of MEP1B mRNA
enilconazole results in decreased expression of MEP1B mRNA
CTD PMID:29106682 PMID:32814239 NCBI chr18:12,366,126...12,392,840
Ensembl chr18:12,365,289...12,392,840
JBrowse link
G Mlxipl MLX interacting protein-like decreases expression ISO enilconazole results in decreased expression of MLXIPL mRNA CTD PMID:32201337 NCBI chr12:21,541,608...21,577,120
Ensembl chr12:21,543,576...21,577,112
JBrowse link
G Mme membrane metallo-endopeptidase multiple interactions
increases expression
EXP [enilconazole co-treated with clothianidin] results in increased expression of MME mRNA; [thiacloprid co-treated with enilconazole] results in increased expression of MME mRNA
enilconazole results in increased expression of MME mRNA
CTD PMID:33426623 NCBI chr 2:147,686,913...147,803,808
Ensembl chr 2:147,722,086...147,803,792
JBrowse link
G Mttp microsomal triglyceride transfer protein decreases expression ISO enilconazole results in decreased expression of MTTP mRNA CTD PMID:32201337 NCBI chr 2:226,613,090...226,654,239
Ensembl chr 2:226,613,090...226,654,239
JBrowse link
G Muc1 mucin 1, cell surface associated affects expression
decreases expression
ISO enilconazole affects the expression of MUC1 mRNA
enilconazole results in decreased expression of MUC1 mRNA
CTD PMID:29106682 PMID:32814239 NCBI chr 2:174,635,989...174,640,738
Ensembl chr 2:174,635,995...174,640,733
JBrowse link
G Muc2 mucin 2, oligomeric mucus/gel-forming affects expression
decreases expression
ISO enilconazole affects the expression of MUC2 mRNA
enilconazole results in decreased expression of MUC2 mRNA
CTD PMID:29106682 PMID:32814239 NCBI chr 1:196,799,494...196,831,740
Ensembl chr 1:196,799,517...196,831,756
JBrowse link
G Muc3 mucin 3 decreases expression ISO enilconazole results in decreased expression of MUC17 mRNA CTD PMID:32814239 NCBI chr12:19,527,251...19,536,924
Ensembl chr12:19,527,321...19,538,522
JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 multiple interactions
decreases expression
ISO [clothianidin co-treated with enilconazole] results in decreased expression of NR0B2 mRNA
enilconazole results in decreased expression of NR0B2 mRNA
CTD PMID:32201337 NCBI chr 5:145,779,294...145,782,609
Ensembl chr 5:145,779,294...145,782,609
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 decreases expression
increases expression
ISO enilconazole results in decreased expression of NR1H4 mRNA
enilconazole results in increased expression of NR1H4 mRNA
CTD PMID:29451352 PMID:32814239 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions
increases activity
ISO [enilconazole co-treated with methidathion] results in increased activity of NR1I2 protein; enilconazole binds to and results in increased activity of NR1I2 protein; enilconazole inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]
enilconazole results in increased activity of NR1I2 protein
CTD PMID:16565514 PMID:17438109 PMID:21115097 PMID:25028461 PMID:29973476 More... NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions
affects response to substance
ISO enilconazole binds to and results in increased activity of NR1I3 protein; enilconazole inhibits the reaction [Androstane-3,17-diol binds to and results in decreased activity of NR1I3 protein]
NR1I3 protein affects the susceptibility to enilconazole
CTD PMID:18832183 PMID:27853109 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 decreases expression ISO enilconazole results in decreased expression of PDK4 mRNA CTD PMID:32201337 NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850
JBrowse link
G Pnpla3 patatin-like phospholipase domain containing 3 decreases expression ISO enilconazole results in decreased expression of PNPLA3 mRNA CTD PMID:32201337 NCBI chr 7:115,293,538...115,314,077
Ensembl chr 7:115,293,538...115,314,077
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO enilconazole binds to and results in increased activity of PPARG protein CTD PMID:33049310 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha decreases expression ISO enilconazole results in decreased expression of PPARGC1A mRNA CTD PMID:32201337 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO [enilconazole binds to and results in decreased activity of PTGS2 protein] which results in decreased chemical synthesis of and results in decreased secretion of Prostaglandin D2 CTD PMID:26359731 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rara retinoic acid receptor, alpha increases activity ISO enilconazole results in increased activity of RARA protein CTD PMID:20143881 NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142
JBrowse link
G Rarg retinoic acid receptor, gamma increases activity ISO enilconazole results in increased activity of RARG protein CTD PMID:20143881 NCBI chr 7:133,367,833...133,390,301
Ensembl chr 7:133,367,833...133,390,177
JBrowse link
G Retnlb resistin like beta affects expression ISO enilconazole affects the expression of RETNLB mRNA CTD PMID:29106682 NCBI chr11:51,983,482...51,985,368
Ensembl chr11:51,983,483...51,985,368
JBrowse link
G Rgcc regulator of cell cycle increases expression ISO enilconazole results in increased expression of RGCC mRNA CTD PMID:32201337 NCBI chr15:54,662,483...54,675,320
Ensembl chr15:54,662,483...54,681,141
JBrowse link
G Rora RAR-related orphan receptor A multiple interactions ISO enilconazole binds to and results in decreased activity of RORA protein CTD PMID:22289359 NCBI chr 8:69,301,635...70,034,741
Ensembl chr 8:69,301,733...70,025,931
JBrowse link
G Scd stearoyl-CoA desaturase decreases expression ISO enilconazole results in decreased expression of SCD mRNA CTD PMID:32201337 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
JBrowse link
G Slc10a1 solute carrier family 10 member 1 decreases expression ISO enilconazole results in decreased expression of SLC10A1 mRNA CTD PMID:29451352 NCBI chr 6:100,613,045...100,626,670
Ensembl chr 6:100,613,045...100,626,670
JBrowse link
G Slc10a2 solute carrier family 10 member 2 increases expression ISO enilconazole results in increased expression of SLC10A2 mRNA CTD PMID:32814239 NCBI chr16:84,386,528...84,409,475
Ensembl chr16:84,374,862...84,409,475
JBrowse link
G Slc12a2 solute carrier family 12 member 2 decreases expression ISO enilconazole results in decreased expression of SLC12A2 mRNA; enilconazole results in decreased expression of SLC12A2 protein CTD PMID:29106682 PMID:32814239 NCBI chr18:51,348,282...51,416,448
Ensembl chr18:51,348,302...51,416,440
JBrowse link
G Slc22a5 solute carrier family 22 member 5 decreases expression ISO enilconazole results in decreased expression of SLC22A5 mRNA; enilconazole results in decreased expression of SLC22A5 protein CTD PMID:36150497 NCBI chr10:38,008,303...38,035,474
Ensembl chr10:38,008,311...38,035,309
JBrowse link
G Slc26a3 solute carrier family 26 member 3 decreases expression ISO enilconazole results in decreased expression of SLC26A3 mRNA; enilconazole results in decreased expression of SLC26A3 protein CTD PMID:29106682 PMID:32814239 NCBI chr 6:48,023,892...48,064,829
Ensembl chr 6:48,023,892...48,064,772
JBrowse link
G Slc26a6 solute carrier family 26 member 6 decreases expression ISO enilconazole results in decreased expression of SLC26A6 mRNA; enilconazole results in decreased expression of SLC26A6 protein CTD PMID:29106682 PMID:32814239 NCBI chr 8:109,558,968...109,569,778
Ensembl chr 8:109,559,642...109,569,778
JBrowse link
G Slc6a1 solute carrier family 6 member 1 multiple interactions EXP [enilconazole co-treated with clothianidin] results in decreased expression of SLC6A1 mRNA; [thiacloprid co-treated with enilconazole] results in decreased expression of SLC6A1 mRNA CTD PMID:33426623 NCBI chr 4:147,448,961...147,482,295
Ensembl chr 4:147,466,965...147,482,293
JBrowse link
G Slc9a3 solute carrier family 9 member A3 decreases expression ISO enilconazole results in decreased expression of SLC9A3 mRNA CTD PMID:29106682 PMID:32814239 NCBI chr 1:29,124,633...29,167,912
Ensembl chr 1:29,124,674...29,167,417
JBrowse link
G Slco4a1 solute carrier organic anion transporter family, member 4a1 increases expression ISO enilconazole results in increased expression of SLCO4A1 mRNA CTD PMID:32201337 NCBI chr 3:167,559,177...167,578,307
Ensembl chr 3:167,559,316...167,578,305
JBrowse link
G Sod1 superoxide dismutase 1 increases expression ISO enilconazole results in increased expression of SOD1 mRNA CTD PMID:29451352 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sod2 superoxide dismutase 2 decreases expression ISO enilconazole results in decreased expression of SOD2 mRNA CTD PMID:29451352 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Star steroidogenic acute regulatory protein affects expression
decreases expression
ISO
EXP
enilconazole affects the expression of STAR mRNA
enilconazole results in decreased expression of STAR mRNA
CTD PMID:30853599 PMID:36410587 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
JBrowse link
G Sult1b1 sulfotransferase family 1B member 1 decreases expression ISO enilconazole results in decreased expression of SULT1B1 mRNA CTD PMID:32201337 NCBI chr14:20,492,763...20,505,491
Ensembl chr14:20,492,708...20,505,483
JBrowse link
G Sult1c2a sulfotransferase family 1C member 2A increases expression ISO enilconazole results in increased expression of SULT1C2 mRNA CTD PMID:32201337 NCBI chr 9:6,873,697...6,904,736
Ensembl chr 9:6,874,249...6,904,734
JBrowse link
G Tff3 trefoil factor 3 decreases expression ISO enilconazole results in decreased expression of TFF3 mRNA CTD PMID:32201337 NCBI chr20:9,193,259...9,197,969
Ensembl chr20:9,193,262...9,198,054
JBrowse link
G Thra thyroid hormone receptor alpha multiple interactions ISO enilconazole binds to and results in decreased activity of THRA protein CTD PMID:33049310 NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936
JBrowse link
G Tnf tumor necrosis factor increases expression ISO enilconazole results in increased expression of TNF mRNA CTD PMID:27393971 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 decreases expression ISO enilconazole results in decreased expression of UGT2B7 mRNA CTD PMID:32201337 NCBI chr14:20,896,682...20,919,604
Ensembl chr14:20,896,682...20,919,604
JBrowse link
isoconazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO isoconazole results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
JBrowse link
ketoconazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin decreases expression EXP Ketoconazole results in decreased expression of A2M mRNA CTD PMID:18289764 NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786
JBrowse link
G Aadat aminoadipate aminotransferase affects expression EXP Ketoconazole affects the expression of AADAT mRNA CTD PMID:18355885 NCBI chr16:29,509,392...29,544,332
Ensembl chr16:29,509,394...29,544,332
JBrowse link
G Aamp angio-associated, migratory cell protein increases expression ISO Ketoconazole results in increased expression of AAMP mRNA CTD PMID:36621641 NCBI chr 9:75,863,382...75,869,188
Ensembl chr 9:75,863,389...75,868,547
JBrowse link
G Aatf apoptosis antagonizing transcription factor decreases expression EXP Ketoconazole results in decreased expression of AATF mRNA CTD PMID:25787151 NCBI chr10:69,299,029...69,392,207
Ensembl chr10:69,299,037...69,392,201
JBrowse link
G Abat 4-aminobutyrate aminotransferase increases expression EXP Ketoconazole results in increased expression of ABAT mRNA CTD PMID:37077353 NCBI chr10:6,996,688...7,092,835
Ensembl chr10:6,999,819...7,092,835
JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 multiple interactions
decreases expression
EXP Ketoconazole inhibits the reaction [Clofibrate results in increased expression of ABCA1 mRNA]
Ketoconazole results in decreased expression of ABCA1 mRNA
CTD PMID:14690017 PMID:37077353 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
JBrowse link
G Abca3 ATP binding cassette subfamily A member 3 decreases expression EXP Ketoconazole results in decreased expression of ABCA3 mRNA CTD PMID:37077353 NCBI chr10:13,382,439...13,439,748
Ensembl chr10:13,382,540...13,439,745
JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions
decreases activity
ISO [Ketoconazole results in decreased activity of ABCB11 protein] which results in decreased export of Taurodeoxycholic Acid; Ketoconazole inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid] CTD PMID:20147439 PMID:20829430 PMID:23956101 PMID:24014644 PMID:28437613 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A increases transport
decreases expression
multiple interactions
affects expression
decreases activity
ISO
EXP
ABCB1 protein results in increased transport of Ketoconazole
Ketoconazole results in decreased expression of ABCB1A mRNA
Ketoconazole inhibits the reaction [Genistein results in increased expression of ABCB1A mRNA]
Ketoconazole affects the expression of ABCB1 mRNA
Ketoconazole inhibits the reaction [ABCB1A protein results in increased secretion of fluorexon]; Ketoconazole inhibits the reaction [Pregnenolone Carbonitrile results in increased expression of ABCB1 mRNA]; Ketoconazole inhibits the reaction [Pregnenolone Carbonitrile results in increased expression of ABCB1 protein]
Ketoconazole results in decreased expression of ABCB1 mRNA
Ketoconazole results in decreased activity of ABCB1 protein
[Ketoconazole binds to and results in decreased activity of ABCB1 protein] which results in decreased export of Digoxin; [Ketoconazole results in decreased activity of ABCB1 protein] which results in increased uptake of Digoxin; Ketoconazole binds to and results in decreased activity of ABCB1 protein; Ketoconazole inhibits the reaction [3,3'-diindolylmethane results in increased expression of ABCB1 mRNA]; Ketoconazole inhibits the reaction [ABCB1 protein affects the transport of Digoxin]; Ketoconazole inhibits the reaction [ABCB1 protein results in increased chemical synthesis of globotriaosylceramide]; Ketoconazole inhibits the reaction [ABCB1 protein results in increased chemical synthesis of Glucosylceramides]; Ketoconazole inhibits the reaction [ABCB1 protein results in increased chemical synthesis of Lactosylceramides]; Ketoconazole inhibits the reaction [ABCB1 protein results in increased secretion of fluorexon]; Ketoconazole inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]; Ketoconazole inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]; Ketoconazole inhibits the reaction [Doxorubicin results in increased expression of ABCB1 mRNA]; Ketoconazole inhibits the reaction [Ethanol results in increased expression of ABCB1 mRNA]; Ketoconazole inhibits the reaction [Hydrogen Peroxide affects the expression of ABCB1 mRNA]; Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [piperine results in increased expression of ABCB1 mRNA]]; Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [piperine results in increased expression of ABCB1 protein]]; Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of ABCB1 mRNA]]; Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of ABCB1 protein]]; Ketoconazole inhibits the reaction [Paclitaxel results in increased expression of ABCB1 mRNA]; Ketoconazole inhibits the reaction [Paclitaxel results in increased expression of ABCB1 protein]; Ketoconazole inhibits the reaction [Rifampin results in increased expression of ABCB1 mRNA]; Ketoconazole inhibits the reaction [Rifampin results in increased expression of ABCB1 protein]; Ketoconazole inhibits the reaction [Spironolactone results in increased expression of ABCB1 protein]; Ketoconazole inhibits the reaction [titanium dioxide results in increased expression of ABCB1 mRNA]
CTD PMID:10350002 PMID:12235267 PMID:14662772 PMID:15969931 PMID:16819505 More... NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 decreases activity
multiple interactions
ISO
EXP
Ketoconazole results in decreased activity of ABCB4 protein
[Chenodeoxycholic Acid co-treated with Ketoconazole] results in increased expression of ABCB4 mRNA
CTD PMID:28437613 PMID:30985903 NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions ISO Ketoconazole inhibits the reaction [titanium dioxide results in increased expression of ABCC1 mRNA] CTD PMID:33766574 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 decreases activity
multiple interactions
ISO
EXP
Ketoconazole results in decreased activity of ABCC2 protein
Ketoconazole inhibits the reaction [Spironolactone results in increased expression of ABCC2 mRNA]
CTD PMID:19070657 PMID:19766108 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Abcd2 ATP binding cassette subfamily D member 2 increases expression EXP Ketoconazole results in increased expression of ABCD2 mRNA CTD PMID:36653537 NCBI chr 7:122,263,034...122,311,642
Ensembl chr 7:122,263,032...122,311,642
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions
increases expression
EXP Ketoconazole inhibits the reaction [Genistein results in increased expression of ABCG2 mRNA]
Ketoconazole results in increased expression of ABCG2 mRNA
CTD PMID:32185415 PMID:37077353 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
JBrowse link
G Abracl ABRA C-terminal like decreases expression ISO Ketoconazole results in decreased expression of ABRACL mRNA CTD PMID:36621641 NCBI chr 1:12,654,951...12,665,143
Ensembl chr 1:12,654,838...12,665,207
JBrowse link
G Acaa1a acetyl-CoA acyltransferase 1A increases expression EXP Ketoconazole results in increased expression of ACAA1 mRNA CTD PMID:37077353 NCBI chr 8:119,079,401...119,088,626
Ensembl chr 8:119,079,775...119,088,624
JBrowse link
G Acaa2 acetyl-CoA acyltransferase 2 increases expression EXP Ketoconazole results in increased expression of ACAA2 mRNA CTD PMID:37077353 NCBI chr18:68,345,136...68,373,246
Ensembl chr18:68,345,012...68,373,249
JBrowse link
G Acadl acyl-CoA dehydrogenase, long chain increases expression EXP Ketoconazole results in increased expression of ACADL mRNA CTD PMID:37077353 NCBI chr 9:68,333,981...68,372,149
Ensembl chr 9:68,333,980...68,372,220
JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain increases expression EXP Ketoconazole results in increased expression of ACADM mRNA CTD PMID:37077353 NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147
JBrowse link
G Acads acyl-CoA dehydrogenase short chain increases expression EXP Ketoconazole results in increased expression of ACADS mRNA CTD PMID:37077353 NCBI chr12:41,493,650...41,502,897
Ensembl chr12:41,493,626...41,502,898
JBrowse link
G Ace2 angiotensin converting enzyme 2 increases expression ISO Ketoconazole results in increased expression of ACE2 mRNA CTD PMID:32808185 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977
JBrowse link
G Acot8 acyl-CoA thioesterase 8 increases expression EXP Ketoconazole results in increased expression of ACOT8 mRNA CTD PMID:37077353 NCBI chr 3:153,531,192...153,542,851
Ensembl chr 3:153,531,193...153,542,851
JBrowse link
G Acsl4 acyl-CoA synthetase long-chain family member 4 decreases expression EXP Ketoconazole results in decreased expression of ACSL4 mRNA CTD PMID:37077353 NCBI chr  X:105,942,794...106,006,573
Ensembl chr  X:105,942,799...106,006,427
JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 increases expression EXP Ketoconazole results in increased expression of ACSL5 mRNA CTD PMID:37077353 NCBI chr 1:254,289,513...254,336,608
Ensembl chr 1:254,292,521...254,336,607
JBrowse link
G Acsm1 acyl-CoA synthetase medium-chain family member 1 decreases expression EXP Ketoconazole results in decreased expression of ACSM1 mRNA CTD PMID:28263823 NCBI chr 1:173,985,715...174,020,565
Ensembl chr 1:173,984,672...174,025,495
JBrowse link
G Adam9 ADAM metallopeptidase domain 9 affects expression EXP Ketoconazole affects the expression of ADAM9 mRNA CTD PMID:25787151 NCBI chr16:67,022,538...67,101,647
Ensembl chr16:67,022,655...67,100,917
JBrowse link
G Adcy6 adenylate cyclase 6 decreases expression EXP Ketoconazole results in decreased expression of ADCY6 mRNA CTD PMID:37077353 NCBI chr 7:129,742,827...129,763,922
Ensembl chr 7:129,742,838...129,763,754
JBrowse link
G Adh1c alcohol dehydrogenase 1C (class I), gamma polypeptide decreases expression EXP Ketoconazole results in decreased expression of ADH1 mRNA CTD PMID:36653537 NCBI chr 2:226,797,303...226,808,892
Ensembl chr 2:226,797,303...226,808,892
JBrowse link
G Adi1 acireductone dioxygenase 1 decreases expression ISO Ketoconazole results in decreased expression of ADI1 mRNA CTD PMID:36621641 NCBI chr 6:45,306,885...45,313,847
Ensembl chr 6:45,306,841...45,313,842
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing increases expression EXP Ketoconazole results in increased expression of ADIPOQ mRNA CTD PMID:36653537 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Adipor2 adiponectin receptor 2 increases expression EXP Ketoconazole results in increased expression of ADIPOR2 mRNA CTD PMID:37077353 NCBI chr 4:152,524,604...152,588,848
Ensembl chr 4:152,524,623...152,559,355
JBrowse link
G Adora1 adenosine A1 receptor increases expression EXP Ketoconazole results in increased expression of ADORA1 mRNA CTD PMID:37077353 NCBI chr13:45,658,872...45,695,821
Ensembl chr13:45,658,872...45,695,801
JBrowse link
G Adrb2 adrenoceptor beta 2 increases expression EXP Ketoconazole results in increased expression of ADRB2 mRNA CTD PMID:37077353 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
JBrowse link
G Aebp2 AE binding protein 2 decreases expression ISO Ketoconazole results in decreased expression of AEBP2 mRNA CTD PMID:36621641 NCBI chr 4:173,527,881...173,566,033
Ensembl chr 4:173,528,344...173,593,100
JBrowse link
G Agps alkylglycerone phosphate synthase increases expression ISO Ketoconazole results in increased expression of AGPS mRNA CTD PMID:36621641 NCBI chr 3:60,747,323...60,845,831
Ensembl chr 3:60,747,323...60,845,830
JBrowse link
G Agrp agouti related neuropeptide decreases expression EXP Ketoconazole results in decreased expression of AGRP mRNA CTD PMID:37077353 NCBI chr19:33,447,992...33,481,602
Ensembl chr19:33,447,992...33,449,584
JBrowse link
G Agt angiotensinogen increases expression EXP Ketoconazole results in increased expression of AGT mRNA CTD PMID:37077353 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions
increases expression
increases activity
ISO
EXP
AHR promotes the reaction [Ketoconazole results in increased expression of NQO1 mRNA]; AHR promotes the reaction [Ketoconazole results in increased expression of NQO1 protein]; Ketoconazole inhibits the reaction [Phenobarbital results in increased expression of AHR protein]
Ketoconazole results in increased expression of AHR mRNA
Ketoconazole results in increased activity of AHR protein
[Ketoconazole results in increased activity of AHR protein] which results in increased activity of and results in increased localization of NFE2L2 protein; [Ketoconazole results in increased activity of and results in increased localization of AHR protein] which results in increased expression of CYP1A1 mRNA; [Ketoconazole results in increased activity of and results in increased localization of AHR protein] which results in increased expression of CYP1A1 protein; AHR protein promotes the reaction [Ketoconazole inhibits the reaction [TNF protein results in increased abundance of Reactive Oxygen Species]]; AHR protein promotes the reaction [Ketoconazole inhibits the reaction [TNF protein results in increased expression of CXCL8 protein]]; Ketoconazole results in increased activity of and results in increased localization of AHR protein
Ketoconazole inhibits the reaction [Phenobarbital results in increased expression of AHR mRNA]; Ketoconazole inhibits the reaction [Phenobarbital results in increased expression of AHR protein]; Ketoconazole inhibits the reaction [Phenytoin results in increased expression of AHR protein]
CTD PMID:17505019 PMID:17923278 PMID:21753779 PMID:25000292 PMID:31168027 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Ahrr aryl-hydrocarbon receptor repressor multiple interactions
increases expression
EXP [Ketoconazole co-treated with Carbon Tetrachloride] results in increased expression of AHRR mRNA
Ketoconazole results in increased expression of AHRR mRNA
CTD PMID:31168027 NCBI chr 1:28,993,634...29,088,673
Ensembl chr 1:28,993,634...29,088,673
JBrowse link
G Ahsg alpha-2-HS-glycoprotein increases expression EXP Ketoconazole results in increased expression of AHSG mRNA CTD PMID:36653537 NCBI chr11:78,121,388...78,127,998
Ensembl chr11:78,117,918...78,145,999
JBrowse link
G Akap12 A-kinase anchoring protein 12 decreases expression ISO Ketoconazole results in decreased expression of AKAP12 mRNA CTD PMID:36621641 NCBI chr 1:40,730,123...40,819,863
Ensembl chr 1:40,730,123...40,819,886
JBrowse link
G Akr1b7 aldo-keto reductase family 1, member B7 increases expression EXP Ketoconazole results in increased expression of AKR1B7 mRNA CTD PMID:36653537 NCBI chr 4:63,053,560...63,100,934
Ensembl chr 4:63,076,800...63,089,502
JBrowse link
G Akr1c15 aldo-keto reductase family 1, member C15 increases expression EXP Ketoconazole results in increased expression of AKR1C15 mRNA CTD PMID:36653537 NCBI chr17:66,181,493...66,208,090
Ensembl chr17:66,181,493...66,208,061
JBrowse link
G Alas1 5'-aminolevulinate synthase 1 increases expression EXP Ketoconazole results in increased expression of ALAS1 mRNA CTD PMID:36653537 NCBI chr 8:106,876,514...106,889,917
Ensembl chr 8:106,876,514...106,889,917
JBrowse link
G Alb albumin affects expression EXP Ketoconazole affects the expression of ALB mRNA CTD PMID:36653537 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 affects expression EXP Ketoconazole affects the expression of ALDH1A1 mRNA CTD PMID:18355885 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
JBrowse link
G Aldh1a7 aldehyde dehydrogenase family 1, subfamily A7 affects expression EXP Ketoconazole affects the expression of ALDH1A4 mRNA CTD PMID:18355885 NCBI chr 1:218,201,443...218,241,410
Ensembl chr 1:218,201,472...218,248,906
JBrowse link
G Aldh7a1 aldehyde dehydrogenase 7 family, member A1 decreases expression ISO Ketoconazole results in decreased expression of ALDH7A1 mRNA CTD PMID:36621641 NCBI chr18:50,003,242...50,042,193
Ensembl chr18:50,009,934...50,042,193
JBrowse link
G Alkbh7 alkB homolog 7 decreases expression EXP Ketoconazole results in decreased expression of ALKBH7 mRNA CTD PMID:36653537 NCBI chr 9:1,838,886...1,841,044
Ensembl chr 9:1,838,811...1,841,044
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated multiple interactions
increases expression
ISO Ketoconazole inhibits the reaction [Calcifediol results in increased expression of ALPL mRNA]
Ketoconazole results in increased expression of ALPL protein
CTD PMID:21542014 PMID:31099283 NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446
JBrowse link
G Amdhd1 amidohydrolase domain containing 1 decreases expression ISO Ketoconazole results in decreased expression of AMDHD1 mRNA CTD PMID:31099283 NCBI chr 7:28,043,923...28,059,156
Ensembl chr 7:28,043,716...28,059,156
JBrowse link
G Amh anti-Mullerian hormone increases expression ISO Ketoconazole results in increased expression of AMH protein CTD PMID:16684832 NCBI chr 7:8,906,776...8,909,192
Ensembl chr 7:8,906,836...8,909,282
JBrowse link
G Ang angiogenin increases expression ISO Ketoconazole results in increased expression of ANG mRNA CTD PMID:36621641 NCBI chr15:24,312,711...24,323,361 JBrowse link
G Anxa1 annexin A1 decreases expression EXP Ketoconazole results in decreased expression of ANXA1 mRNA CTD PMID:25787151 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
JBrowse link
G Aox1 aldehyde oxidase 1 decreases expression EXP Ketoconazole results in decreased expression of AOX1 mRNA CTD PMID:36653537 NCBI chr 9:59,579,621...59,658,772
Ensembl chr 9:59,579,649...59,658,770
JBrowse link
G Ap1s1 adaptor related protein complex 1 subunit sigma 1 decreases expression ISO Ketoconazole results in decreased expression of AP1S1 mRNA CTD PMID:17175557 NCBI chr12:19,625,267...19,635,792
Ensembl chr12:19,625,332...19,756,713
JBrowse link
G Ap3m1 adaptor related protein complex 3 subunit mu 1 decreases expression ISO Ketoconazole results in decreased expression of AP3M1 mRNA CTD PMID:36621641 NCBI chr15:3,246,616...3,264,846
Ensembl chr15:3,246,926...3,264,844
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 decreases expression EXP Ketoconazole results in decreased expression of APAF1 mRNA CTD PMID:37077353 NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540
JBrowse link
G Apoa1 apolipoprotein A1 increases expression EXP Ketoconazole results in increased expression of APOA1 mRNA CTD PMID:36653537 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
JBrowse link
G Apoa4 apolipoprotein A4 affects expression EXP Ketoconazole affects the expression of APOA4 mRNA CTD PMID:18355885 NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469
JBrowse link
G Apoe apolipoprotein E increases expression EXP Ketoconazole results in increased expression of APOE mRNA CTD PMID:37077353 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Ar androgen receptor multiple interactions
decreases expression
increases activity
decreases activity
ISO
EXP
[Goserelin co-treated with Dutasteride co-treated with bicalutamide co-treated with Ketoconazole] results in decreased expression of AR protein; Ketoconazole inhibits the reaction [Metribolone results in increased activity of AR protein]; Ketoconazole inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]
Ketoconazole inhibits the reaction [Phenytoin results in increased expression of AR protein]
Ketoconazole results in decreased expression of AR protein
Ketoconazole results in increased activity of AR protein
Ketoconazole results in decreased activity of AR protein
CTD PMID:11118046 PMID:18324785 PMID:19226368 PMID:19587329 PMID:24323034 More... NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Arg1 arginase 1 increases expression EXP Ketoconazole results in increased expression of ARG1 mRNA CTD PMID:37077353 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422
JBrowse link
G Asb17 ankyrin repeat and SOCS box-containing 17 increases expression ISO Ketoconazole results in increased expression of ASB17 mRNA CTD PMID:31099283 NCBI chr 2:242,775,887...242,786,950
Ensembl chr 2:242,775,994...242,786,903
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) increases expression ISO Ketoconazole results in increased expression of ASNS mRNA CTD PMID:15342952 PMID:17175557 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
JBrowse link
G Ass1 argininosuccinate synthase 1 increases expression EXP Ketoconazole results in increased expression of ASS1 mRNA CTD PMID:36653537 NCBI chr 3:14,747,355...14,796,909
Ensembl chr 3:14,747,368...14,796,903
JBrowse link
G Atad2 ATPase family, AAA domain containing 2 increases expression ISO Ketoconazole results in increased expression of ATAD2 mRNA CTD PMID:36621641 NCBI chr 7:89,634,123...89,676,738
Ensembl chr 7:89,634,123...89,676,738
JBrowse link
G Atf1 activating transcription factor 1 multiple interactions ISO Bucladesine inhibits the reaction [Ketoconazole inhibits the reaction [Dinoprostone results in increased phosphorylation of ATF1 protein]]; Ketoconazole inhibits the reaction [Dinoprostone promotes the reaction [ATF1 protein modified form binds to PTGS2 promoter]]; Ketoconazole inhibits the reaction [Dinoprostone results in increased phosphorylation of ATF1 protein] CTD PMID:12164941 NCBI chr 7:131,361,962...131,404,677
Ensembl chr 7:131,362,450...131,404,670
JBrowse link
G Atp5mc2 ATP synthase membrane subunit c locus 2 increases expression ISO Ketoconazole results in increased expression of ATP5MC2 mRNA CTD PMID:36621641 NCBI chr 7:133,791,341...133,799,713
Ensembl chr 7:133,791,342...133,799,733
JBrowse link
G Atp5po ATP synthase peripheral stalk subunit OSCP increases expression EXP Ketoconazole results in increased expression of ATP5PO mRNA CTD PMID:37077353 NCBI chr11:31,165,218...31,171,530
Ensembl chr11:31,165,217...31,171,592
JBrowse link
G Atp6v1d ATPase H+ transporting V1 subunit D increases expression EXP Ketoconazole results in increased expression of ATP6V1D mRNA CTD PMID:37077353 NCBI chr 6:97,656,725...97,672,295
Ensembl chr 6:97,656,576...97,672,303
JBrowse link
G Avp arginine vasopressin increases expression EXP Ketoconazole results in increased expression of AVP mRNA CTD PMID:37077353 NCBI chr 3:117,793,447...117,805,091
Ensembl chr 3:117,793,457...117,795,425
JBrowse link
G Bace1 beta-secretase 1 decreases expression EXP Ketoconazole results in decreased expression of BACE1 mRNA CTD PMID:37077353 NCBI chr 8:46,142,060...46,166,268
Ensembl chr 8:46,142,116...46,165,876
JBrowse link
G Bad BCL2-associated agonist of cell death increases expression EXP Ketoconazole results in increased expression of BAD mRNA CTD PMID:25787151 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO [Ketoconazole inhibits the reaction [CYP3A4 protein results in increased susceptibility to Amodiaquine]] which results in increased expression of BAX protein; Ketoconazole inhibits the reaction [Calcifediol results in decreased expression of BAX mRNA] CTD PMID:21542014 PMID:31629065 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO [Ketoconazole inhibits the reaction [CYP3A4 protein results in increased susceptibility to Amodiaquine]] which results in decreased expression of BCL2 protein; Ketoconazole inhibits the reaction [Calcifediol results in increased expression of BCL2 mRNA] CTD PMID:21542014 PMID:31629065 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bcl2l11 Bcl2-like 11 increases expression ISO Ketoconazole results in increased expression of BCL2L11 mRNA CTD PMID:25808816 NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068
JBrowse link
G Becn1 beclin 1 increases expression EXP Ketoconazole results in increased expression of BECN1 mRNA CTD PMID:37077353 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Bhmt betaine-homocysteine S-methyltransferase affects expression EXP Ketoconazole affects the expression of BHMT mRNA CTD PMID:18355885 NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742
JBrowse link
G Bicc1 BicC family RNA binding protein 1 decreases expression ISO Ketoconazole results in decreased expression of BICC1 mRNA CTD PMID:31099283 NCBI chr20:17,449,639...17,686,775
Ensembl chr20:17,449,560...17,686,776
JBrowse link
G Bid BH3 interacting domain death agonist increases expression ISO Ketoconazole results in increased expression of BID mRNA CTD PMID:25808816 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Bin1 bridging integrator 1 increases expression EXP Ketoconazole results in increased expression of BIN1 mRNA CTD PMID:37077353 NCBI chr18:24,009,731...24,067,267
Ensembl chr18:24,009,653...24,067,263
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 increases expression EXP Ketoconazole results in increased expression of BIRC5 mRNA CTD PMID:37077353 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Bmp2 bone morphogenetic protein 2 multiple interactions ISO Ketoconazole inhibits the reaction [menatetrenone promotes the reaction [Phosphates results in increased expression of BMP2 mRNA]]; Ketoconazole inhibits the reaction [Phosphates promotes the reaction [menatetrenone results in increased expression of BMP2 mRNA]] CTD PMID:31843813 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397
JBrowse link
G Bmp4 bone morphogenetic protein 4 decreases expression EXP Ketoconazole results in decreased expression of BMP4 mRNA CTD PMID:36653537 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
JBrowse link
G Bmp6 bone morphogenetic protein 6 increases expression ISO Ketoconazole results in increased expression of BMP6 mRNA CTD PMID:32816093 NCBI chr17:26,318,121...26,469,691
Ensembl chr17:26,318,569...26,470,365
JBrowse link
G Bnc1 basonuclin zinc finger protein 1 decreases expression EXP Ketoconazole results in decreased expression of BNC1 mRNA CTD PMID:36653537 NCBI chr 1:135,917,676...135,943,333
Ensembl chr 1:135,917,687...135,943,333
JBrowse link
G Bnip1 BCL2 interacting protein 1 increases expression ISO Ketoconazole results in increased expression of BNIP1 mRNA CTD PMID:25808816 NCBI chr10:16,386,876...16,399,124
Ensembl chr10:16,386,841...16,399,157
JBrowse link
G Bnip2 BCL2 interacting protein 2 increases expression EXP Ketoconazole results in increased expression of BNIP2 mRNA CTD PMID:25808816 NCBI chr 8:70,640,436...70,661,782
Ensembl chr 8:70,640,445...70,675,590
JBrowse link
G Bnip3 BCL2 interacting protein 3 increases expression EXP Ketoconazole results in increased expression of BNIP3 mRNA CTD PMID:25808816 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
JBrowse link
G Bnip3l BCL2 interacting protein 3 like decreases expression ISO Ketoconazole results in decreased expression of BNIP3L mRNA CTD PMID:36621641 NCBI chr15:41,174,594...41,197,730
Ensembl chr15:41,174,594...41,197,803
JBrowse link
G C10h5orf15 similar to human chromosome 5 open reading frame 15 increases expression ISO Ketoconazole results in increased expression of C5ORF15 mRNA CTD PMID:36621641 NCBI chr10:36,563,989...36,576,593
Ensembl chr10:36,563,958...36,576,590
JBrowse link
G C1galt1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1 decreases expression ISO Ketoconazole results in decreased expression of C1GALT1 mRNA CTD PMID:36621641 NCBI chr 4:35,930,981...35,966,100
Ensembl chr 4:35,928,104...35,961,831
JBrowse link
G C1galt1c1 C1GALT1-specific chaperone 1 decreases expression ISO Ketoconazole results in decreased expression of C1GALT1C1 mRNA CTD PMID:36621641 NCBI chr  X:117,378,123...117,382,620
Ensembl chr  X:117,375,525...117,382,787
JBrowse link
G C3 complement C3 increases expression EXP Ketoconazole results in increased expression of C3 mRNA CTD PMID:37077353 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
JBrowse link
G C5h1orf174 similar to human chromosome 1 open reading frame 174 increases expression ISO Ketoconazole results in increased expression of C1ORF174 mRNA CTD PMID:36621641 NCBI chr 5:164,515,578...164,520,022
Ensembl chr 5:164,515,559...164,520,021
JBrowse link
G Cacna1h calcium voltage-gated channel subunit alpha1 H decreases expression EXP Ketoconazole results in decreased expression of CACNA1H mRNA CTD PMID:37077353 NCBI chr10:14,390,104...14,448,204
Ensembl chr10:14,390,113...14,448,376
JBrowse link
G Cacna1i calcium voltage-gated channel subunit alpha1 I decreases expression EXP Ketoconazole results in decreased expression of CACNA1I mRNA CTD PMID:37077353 NCBI chr 7:111,835,996...111,947,418
Ensembl chr 7:111,836,012...111,944,688
JBrowse link
G Cacna2d3 calcium voltage-gated channel auxiliary subunit alpha2delta 3 increases expression EXP Ketoconazole results in increased expression of CACNA2D3 mRNA CTD PMID:37077353 NCBI chr16:4,098,439...4,912,498
Ensembl chr16:4,098,445...4,912,351
JBrowse link
G Cacna2d4 calcium voltage-gated channel auxiliary subunit alpha2delta 4 increases expression EXP Ketoconazole results in increased expression of CACNA2D4 mRNA CTD PMID:37077353 NCBI chr 4:152,408,588...152,521,478
Ensembl chr 4:152,408,657...152,521,268
JBrowse link
G Cacnb1 calcium voltage-gated channel auxiliary subunit beta 1 decreases expression EXP Ketoconazole results in decreased expression of CACNB1 mRNA CTD PMID:37077353 NCBI chr10:82,998,182...83,018,838
Ensembl chr10:82,998,182...83,018,694
JBrowse link
G Cacng3 calcium voltage-gated channel auxiliary subunit gamma 3 increases expression EXP Ketoconazole results in increased expression of CACNG3 mRNA CTD PMID:37077353 NCBI chr 1:177,201,361...177,297,019
Ensembl chr 1:177,201,288...177,297,024
JBrowse link
G Cacng4 calcium voltage-gated channel auxiliary subunit gamma 4 decreases expression EXP Ketoconazole results in decreased expression of CACNG4 mRNA CTD PMID:37077353 NCBI chr10:92,683,778...92,745,842
Ensembl chr10:92,683,761...92,746,126
JBrowse link
G Calb1 calbindin 1 decreases expression ISO Ketoconazole results in decreased expression of CALB1 mRNA CTD PMID:31099283 NCBI chr 5:29,375,624...29,402,532
Ensembl chr 5:29,375,642...29,402,431
JBrowse link
G Calb2 calbindin 2 decreases expression EXP Ketoconazole results in decreased expression of CALB2 mRNA CTD PMID:36653537 NCBI chr19:38,114,435...38,141,438
Ensembl chr19:38,114,424...38,141,438
JBrowse link
G Cap1 cyclase associated actin cytoskeleton regulatory protein 1 increases expression EXP Ketoconazole results in increased expression of CAP1 mRNA CTD PMID:36653537 NCBI chr 5:135,142,108...135,168,885
Ensembl chr 5:135,142,112...135,168,769
JBrowse link
G Car2 carbonic anhydrase 2 increases expression EXP Ketoconazole results in increased expression of CA2 mRNA; Ketoconazole results in increased expression of CAR2 mRNA CTD PMID:37077353 NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818
JBrowse link
G Carmil1 capping protein regulator and myosin 1 linker 1 decreases expression ISO Ketoconazole results in decreased expression of CARMIL1 mRNA CTD PMID:36621641 NCBI chr17:40,807,921...41,088,326
Ensembl chr17:40,808,389...41,088,326
JBrowse link
G Casp12 caspase 12 increases expression ISO Ketoconazole results in increased expression of CASP12 mRNA CTD PMID:25808816 NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037
JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions
ISO Ketoconazole results in increased activity of CASP3 protein
Ketoconazole inhibits the reaction [Galactosamine results in increased activity of CASP3 protein]; pyrazolanthrone inhibits the reaction [Ketoconazole results in increased activity of CASP3 protein]
CTD PMID:17936189 PMID:19631732 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp6 caspase 6 decreases expression
increases expression
EXP Ketoconazole results in decreased expression of CASP6 mRNA
Ketoconazole results in increased expression of CASP6 mRNA
CTD PMID:25787151 PMID:25808816 NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502
JBrowse link
G Casp7 caspase 7 increases expression EXP Ketoconazole results in increased expression of CASP7 mRNA CTD PMID:25808816 NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Casp8ap2 caspase 8 associated protein 2 affects expression ISO Ketoconazole affects the expression of CASP8AP2 mRNA CTD PMID:36621641 NCBI chr 5:47,014,501...47,052,276
Ensembl chr 5:47,014,667...47,052,275
JBrowse link
G Casp9 caspase 9 increases expression ISO Ketoconazole results in increased expression of CASP9 mRNA CTD PMID:25808816 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase decreases expression EXP Ketoconazole results in decreased expression of CAT mRNA CTD PMID:25787151 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cav1 caveolin 1 increases expression ISO Ketoconazole results in increased expression of CAV1 mRNA CTD PMID:36621641 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
JBrowse link
G Cbx7 chromobox 7 increases expression EXP Ketoconazole results in increased expression of CBX7 mRNA CTD PMID:37077353 NCBI chr 7:111,460,656...111,479,231
Ensembl chr 7:111,460,656...111,477,973
JBrowse link
G Ccdc8 coiled-coil domain containing 8 increases expression EXP Ketoconazole results in increased expression of CCDC8 mRNA CTD PMID:36653537 NCBI chr 1:77,679,521...77,682,849
Ensembl chr 1:77,679,218...77,683,090
JBrowse link
G Cck cholecystokinin increases expression EXP Ketoconazole results in increased expression of CCK mRNA CTD PMID:37077353 NCBI chr 8:121,153,499...121,160,194
Ensembl chr 8:121,153,500...121,160,084
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
increases expression
ISO
EXP
Dinoprostone deficiency inhibits the reaction [Ketoconazole inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]]; Dinoprostone deficiency inhibits the reaction [Ketoconazole inhibits the reaction [TNF protein results in increased expression of CCL2 protein]]; Ketoconazole inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]; Ketoconazole inhibits the reaction [TNF protein results in increased expression of CCL2 protein]; PTGER2 protein promotes the reaction [Ketoconazole inhibits the reaction [TNF protein results in increased expression of CCL2 protein]]; PTGER3 protein promotes the reaction [Ketoconazole inhibits the reaction [TNF protein results in increased expression of CCL2 protein]]
Ketoconazole results in increased expression of CCL2 mRNA
CTD PMID:16784723 PMID:37077353 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl27 C-C motif chemokine ligand 27 multiple interactions ISO Dinoprostone deficiency inhibits the reaction [Ketoconazole inhibits the reaction [TNF protein results in increased expression of CCL27 mRNA]]; Dinoprostone deficiency inhibits the reaction [Ketoconazole inhibits the reaction [TNF protein results in increased expression of CCL27 protein]]; Ketoconazole inhibits the reaction [TNF protein results in increased expression of CCL27 mRNA]; Ketoconazole inhibits the reaction [TNF protein results in increased expression of CCL27 protein]; PTGER2 protein promotes the reaction [Ketoconazole inhibits the reaction [TNF protein results in increased expression of CCL27 protein]]; PTGER3 protein promotes the reaction [Ketoconazole inhibits the reaction [TNF protein results in increased expression of CCL27 protein]] CTD PMID:16784723 NCBI chr 5:56,941,402...56,948,511
Ensembl chr 5:56,941,402...56,948,506
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions
increases expression
ISO
EXP
Dinoprostone deficiency inhibits the reaction [Ketoconazole inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA]]; Dinoprostone deficiency inhibits the reaction [Ketoconazole inhibits the reaction [TNF protein results in increased expression of CCL5 protein]]; Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CCL5 mRNA]; Ketoconazole inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA]; Ketoconazole inhibits the reaction [TNF protein results in increased expression of CCL5 protein]; PTGER2 protein promotes the reaction [Ketoconazole inhibits the reaction [TNF protein results in increased expression of CCL5 protein]]; PTGER3 protein promotes the reaction [Ketoconazole inhibits the reaction [TNF protein results in increased expression of CCL5 protein]]
Ketoconazole results in increased expression of CCL5 mRNA
CTD PMID:16784723 PMID:23688403 PMID:37077353 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Ccn1 cellular communication network factor 1 increases expression
affects expression
ISO
EXP
Ketoconazole results in increased expression of CCN1 mRNA
Ketoconazole affects the expression of CCN1 mRNA
CTD PMID:36621641 PMID:36653537 NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484
JBrowse link
G Ccng1 cyclin G1 increases expression EXP Ketoconazole results in increased expression of CCNG1 mRNA CTD PMID:18289764 NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641
JBrowse link
G Cd200 Cd200 molecule increases expression ISO Ketoconazole results in increased expression of CD200 mRNA CTD PMID:36621641 NCBI chr11:55,410,166...55,437,527
Ensembl chr11:55,410,196...55,501,648
JBrowse link
G Cd247 Cd247 molecule multiple interactions ISO Ketoconazole inhibits the reaction [[[CD3G protein binds to CD3D protein binds to CD3E protein binds to CD247 protein] which co-treated with CD28 protein] results in increased abundance of Calcitriol]; Ketoconazole inhibits the reaction [Calcifediol promotes the reaction [[[CD3G protein binds to CD3D protein binds to CD3E protein binds to CD247 protein] which co-treated with CD28 protein] results in increased expression of VDR protein]] CTD PMID:24792400 NCBI chr13:78,043,302...78,118,437
Ensembl chr13:78,043,307...78,122,263
JBrowse link
G Cd274 CD274 molecule decreases expression EXP Ketoconazole results in decreased expression of CD274 mRNA CTD PMID:37077353 NCBI chr 1:227,116,674...227,137,379
Ensembl chr 1:227,116,649...227,134,450
JBrowse link
G Cd28 Cd28 molecule multiple interactions ISO Ketoconazole inhibits the reaction [[[CD3G protein binds to CD3D protein binds to CD3E protein binds to CD247 protein] which co-treated with CD28 protein] results in increased abundance of Calcitriol]; Ketoconazole inhibits the reaction [Calcifediol promotes the reaction [[[CD3G protein binds to CD3D protein binds to CD3E protein binds to CD247 protein] which co-treated with CD28 protein] results in increased expression of VDR protein]] CTD PMID:24792400 NCBI chr 9:62,166,324...62,194,674
Ensembl chr 9:62,166,192...62,194,685
JBrowse link
G Cd3d CD3 delta subunit of T-cell receptor complex multiple interactions ISO Ketoconazole inhibits the reaction [[[CD3G protein binds to CD3D protein binds to CD3E protein binds to CD247 protein] which co-treated with CD28 protein] results in increased abundance of Calcitriol]; Ketoconazole inhibits the reaction [Calcifediol promotes the reaction [[[CD3G protein binds to CD3D protein binds to CD3E protein binds to CD247 protein] which co-treated with CD28 protein] results in increased expression of VDR protein]] CTD PMID:24792400 NCBI chr 8:45,287,803...45,293,342
Ensembl chr 8:45,288,749...45,301,809
JBrowse link
G Cd3e CD3 epsilon subunit of T-cell receptor complex multiple interactions ISO Ketoconazole inhibits the reaction [[[CD3G protein binds to CD3D protein binds to CD3E protein binds to CD247 protein] which co-treated with CD28 protein] results in increased abundance of Calcitriol]; Ketoconazole inhibits the reaction [Calcifediol promotes the reaction [[[CD3G protein binds to CD3D protein binds to CD3E protein binds to CD247 protein] which co-treated with CD28 protein] results in increased expression of VDR protein]] CTD PMID:24792400 NCBI chr 8:45,303,848...45,315,005
Ensembl chr 8:45,303,852...45,315,022
JBrowse link
G Cd3g CD3 gamma subunit of T-cell receptor complex multiple interactions ISO Ketoconazole inhibits the reaction [[[CD3G protein binds to CD3D protein binds to CD3E protein binds to CD247 protein] which co-treated with CD28 protein] results in increased abundance of Calcitriol]; Ketoconazole inhibits the reaction [Calcifediol promotes the reaction [[[CD3G protein binds to CD3D protein binds to CD3E protein binds to CD247 protein] which co-treated with CD28 protein] results in increased expression of VDR protein]] CTD PMID:24792400 NCBI chr 8:45,280,797...45,287,271
Ensembl chr 8:45,281,204...45,287,147
JBrowse link
G Cd47 Cd47 molecule increases expression ISO Ketoconazole results in increased expression of CD47 mRNA CTD PMID:36621641 NCBI chr11:50,906,052...50,970,000
Ensembl chr11:50,906,177...50,969,425
JBrowse link
G Cdc42ep2 CDC42 effector protein 2 decreases expression EXP Ketoconazole results in decreased expression of CDC42EP2 mRNA CTD PMID:36653537 NCBI chr 1:203,202,000...203,210,891
Ensembl chr 1:203,201,873...203,210,897
JBrowse link
G Cdc42ep3 CDC42 effector protein 3 increases expression EXP Ketoconazole results in increased expression of CDC42EP3 mRNA CTD PMID:28263823 NCBI chr 6:15,710,894...15,731,366
Ensembl chr 6:15,708,730...15,732,721
JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression EXP Ketoconazole results in decreased expression of CDK2 mRNA CTD PMID:37077353 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
JBrowse link
G Cdk6 cyclin-dependent kinase 6 decreases expression EXP Ketoconazole results in decreased expression of CDK6 mRNA CTD PMID:37077353 NCBI chr 4:30,637,650...30,829,688
Ensembl chr 4:30,646,460...30,829,634
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO
EXP
Ketoconazole results in increased expression of CDKN1A mRNA CTD PMID:16483768 PMID:25808816 PMID:37077353 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression EXP Ketoconazole results in increased expression of CDKN1B mRNA CTD PMID:25808816 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Cdkn2c cyclin-dependent kinase inhibitor 2C affects expression EXP Ketoconazole affects the expression of CDKN2C mRNA CTD PMID:18355885 NCBI chr 5:124,411,123...124,416,278
Ensembl chr 5:124,411,124...124,416,278
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha increases expression EXP Ketoconazole results in increased expression of CEBPA mRNA CTD PMID:37077353 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
JBrowse link
G Cenpu centromere protein U decreases expression ISO Ketoconazole results in decreased expression of CENPU mRNA CTD PMID:36621641 NCBI chr16:45,715,821...45,739,038
Ensembl chr16:45,714,294...45,738,823
JBrowse link
G Cep15 centrosomal protein 15 increases expression ISO Ketoconazole results in increased expression of CEP15 mRNA CTD PMID:36621641 NCBI chr15:12,815,159...12,835,115
Ensembl chr15:12,818,385...12,833,838
JBrowse link
G Cep19 centrosomal protein 19 increases expression ISO Ketoconazole results in increased expression of CEP19 mRNA CTD PMID:36621641 NCBI chr11:68,677,869...68,687,117
Ensembl chr11:68,677,871...68,687,022
JBrowse link
G Ces2h carboxylesterase 2H affects expression EXP Ketoconazole affects the expression of CES2 mRNA CTD PMID:18355885 NCBI chr19:32,974,242...32,988,842
Ensembl chr19:32,974,242...32,988,830
JBrowse link
G Cfb complement factor B increases expression EXP Ketoconazole results in increased expression of CFB mRNA CTD PMID:36653537 NCBI chr20:3,970,643...3,976,510
Ensembl chr20:3,951,474...3,976,505
JBrowse link
G Cga glycoprotein hormones, alpha polypeptide decreases expression ISO Ketoconazole results in decreased expression of CGA mRNA CTD PMID:25808816 NCBI chr 5:49,486,915...49,499,192
Ensembl chr 5:49,487,068...49,499,191
JBrowse link
G Chrac1 chromatin accessibility complex subunit 1 increases expression ISO Ketoconazole results in increased expression of CHRAC1 mRNA CTD PMID:36621641 NCBI chr 7:105,013,047...105,016,435
Ensembl chr 7:105,013,015...105,017,136
JBrowse link
G Cibar1 CBY1 interacting BAR domain containing 1 decreases expression ISO Ketoconazole results in decreased expression of CIBAR1 mRNA CTD PMID:36621641 NCBI chr 5:25,613,993...25,632,440
Ensembl chr 5:25,614,033...25,632,489
JBrowse link
G Cidea cell death-inducing DFFA-like effector a increases expression EXP Ketoconazole results in increased expression of CIDEA mRNA CTD PMID:36653537 PMID:37077353 NCBI chr18:60,894,917...60,920,485
Ensembl chr18:60,894,874...60,920,481
JBrowse link
G Ckap2l cytoskeleton associated protein 2-like decreases expression ISO Ketoconazole results in decreased expression of CKAP2L mRNA CTD PMID:36621641 NCBI chr 3:116,497,186...116,524,302
Ensembl chr 3:116,498,022...116,524,366
JBrowse link
G Clcf1 cardiotrophin-like cytokine factor 1 increases expression ISO Ketoconazole results in increased expression of CLCF1 mRNA CTD PMID:31099283 NCBI chr 1:201,507,763...201,517,607
Ensembl chr 1:201,507,859...201,517,605
JBrowse link
G Clec4e C-type lectin domain family 4, member E increases expression ISO Ketoconazole results in increased expression of CLEC4E mRNA CTD PMID:31099283 NCBI chr 4:156,606,927...156,612,911
Ensembl chr 4:156,607,614...156,612,767
JBrowse link
G Clmn calmin multiple interactions ISO Ketoconazole promotes the reaction [Calcitriol results in increased expression of CLMN mRNA] CTD PMID:26485663 NCBI chr 6:123,707,710...123,807,283
Ensembl chr 6:123,713,507...123,807,272
JBrowse link
G Cln5 CLN5, intracellular trafficking protein affects expression ISO Ketoconazole affects the expression of CLN5 mRNA CTD PMID:36621641 NCBI chr15:79,893,573...79,903,438
Ensembl chr15:79,893,548...79,903,438
JBrowse link
G Clu clusterin affects expression
decreases expression
EXP Ketoconazole affects the expression of CLU mRNA
Ketoconazole results in decreased expression of CLU mRNA
CTD PMID:17558187 PMID:18289764 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
JBrowse link
G Cmtm6 CKLF-like MARVEL transmembrane domain containing 6 affects expression EXP Ketoconazole affects the expression of CMTM6 mRNA CTD PMID:18355885 NCBI chr 8:114,422,934...114,441,034
Ensembl chr 8:114,422,921...114,441,033
JBrowse link
G Cmtm7 CKLF-like MARVEL transmembrane domain containing 7 increases expression ISO Ketoconazole results in increased expression of CMTM7 mRNA CTD PMID:36621641 NCBI chr 8:114,448,037...114,474,958
Ensembl chr 8:114,448,042...114,474,621
JBrowse link
G Cnr2 cannabinoid receptor 2 decreases expression EXP Ketoconazole results in decreased expression of CNR2 mRNA CTD PMID:36653537 NCBI chr 5:148,125,222...148,151,548
Ensembl chr 5:148,125,604...148,151,548
JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression EXP Ketoconazole results in decreased expression of COL1A1 mRNA CTD PMID:37077353 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Commd2 COMM domain containing 2 decreases expression ISO Ketoconazole results in decreased expression of COMMD2 mRNA CTD PMID:36621641 NCBI chr 2:141,848,661...141,852,907
Ensembl chr 2:141,848,680...141,852,888
JBrowse link
G Cop1 COP1, E3 ubiquitin ligase decreases expression ISO Ketoconazole results in decreased expression of COP1 mRNA CTD PMID:36621641 NCBI chr13:71,467,164...71,561,826
Ensembl chr13:71,429,961...71,538,890
JBrowse link
G Copz1 COPI coat complex subunit zeta 1 decreases expression ISO Ketoconazole results in decreased expression of COPZ1 mRNA CTD PMID:36621641 NCBI chr 7:134,409,523...134,435,661
Ensembl chr 7:134,409,799...134,435,662
JBrowse link
G Cox18 cytochrome c oxidase assembly factor COX18 affects expression ISO Ketoconazole affects the expression of COX18 mRNA CTD PMID:36621641 NCBI chr14:17,864,581...17,877,483
Ensembl chr14:17,865,857...17,877,480
JBrowse link
G Cpn2 carboxypeptidase N subunit 2 decreases expression ISO Ketoconazole results in decreased expression of CPN2 mRNA CTD PMID:31099283 NCBI chr11:70,486,054...70,495,937
Ensembl chr11:70,486,057...70,496,472
JBrowse link
G Cpped1 calcineurin-like phosphoesterase domain containing 1 affects expression EXP Ketoconazole affects the expression of CPPED1 mRNA CTD PMID:18355885 NCBI chr10:3,701,522...3,821,050
Ensembl chr10:3,701,459...3,821,054
JBrowse link
G Cpt1b carnitine palmitoyltransferase 1B decreases expression EXP Ketoconazole results in decreased expression of CPT1B mRNA CTD PMID:37077353 NCBI chr 7:120,491,354...120,500,833
Ensembl chr 7:120,491,354...120,500,404
JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 increases expression EXP Ketoconazole results in increased expression of CPT2 mRNA CTD PMID:37077353 NCBI chr 5:122,664,677...122,682,126
Ensembl chr 5:122,664,677...122,682,095
JBrowse link
G Cr2 complement C3d receptor 2 increases expression EXP Ketoconazole results in increased expression of CR2 mRNA CTD PMID:37077353 NCBI chr13:106,678,579...106,716,595
Ensembl chr13:106,685,413...106,716,235
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions
decreases expression
ISO
EXP
Bucladesine inhibits the reaction [Ketoconazole inhibits the reaction [Dinoprostone results in increased phosphorylation of CREB1 protein]]; Ketoconazole inhibits the reaction [Dinoprostone promotes the reaction [CREB1 protein modified form binds to PTGS2 promoter]]; Ketoconazole inhibits the reaction [Dinoprostone results in increased phosphorylation of CREB1 protein]
Ketoconazole results in decreased expression of CREB1 mRNA
Ketoconazole inhibits the reaction [Arachidonic Acid results in increased phosphorylation of CREB1 protein]; Ketoconazole inhibits the reaction [Epinephrine results in increased phosphorylation of CREB1 protein]
CTD PMID:12164941 PMID:17680988 PMID:37077353 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Crem cAMP responsive element modulator affects expression
decreases expression
EXP Ketoconazole affects the expression of CREM mRNA
Ketoconazole results in decreased expression of CREM mRNA
CTD PMID:18355885 PMID:36653537 NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989
JBrowse link
G Crhr2 corticotropin releasing hormone receptor 2 decreases expression EXP Ketoconazole results in decreased expression of CRHR2 mRNA CTD PMID:37077353 NCBI chr 4:84,222,897...84,265,924
Ensembl chr 4:84,224,002...84,265,904
JBrowse link
G Crls1 cardiolipin synthase 1 increases expression EXP Ketoconazole results in increased expression of CRLS1 mRNA CTD PMID:36653537 NCBI chr 3:120,119,822...120,138,674
Ensembl chr 3:120,119,852...120,138,655
JBrowse link
G Crym crystallin, mu decreases expression EXP Ketoconazole results in decreased expression of CRYM mRNA CTD PMID:36653537 NCBI chr 1:174,560,423...174,575,660
Ensembl chr 1:174,560,416...174,575,633
JBrowse link
G Ctnnb1 catenin beta 1 decreases expression EXP Ketoconazole results in decreased expression of CTNNB1 mRNA CTD PMID:37077353 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Ctsl cathepsin L decreases expression ISO Ketoconazole results in decreased expression of CTSL mRNA CTD PMID:36621641 NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548
JBrowse link
G Ctss cathepsin S affects expression EXP Ketoconazole affects the expression of CTSS mRNA CTD PMID:18289764 NCBI chr 2:183,086,437...183,114,483
Ensembl chr 2:183,086,437...183,114,483
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 multiple interactions ISO Ketoconazole inhibits the reaction [Biological Products results in increased expression of CXCL10 mRNA]; Ketoconazole inhibits the reaction [Biological Products results in increased expression of CXCL10 protein] CTD PMID:24471457 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
JBrowse link
G Cxcl14 C-X-C motif chemokine ligand 14 increases expression EXP Ketoconazole results in increased expression of CXCL14 mRNA CTD PMID:37077353 NCBI chr17:8,317,930...8,325,956
Ensembl chr17:8,317,933...8,324,839
JBrowse link
G Cyba cytochrome b-245 alpha chain increases expression EXP Ketoconazole results in increased expression of CYBA mRNA CTD PMID:37077353 NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721
JBrowse link
G Cycs cytochrome c, somatic decreases expression
increases expression
EXP Ketoconazole results in decreased expression of CYCS mRNA
Ketoconazole results in increased expression of CYCS mRNA
CTD PMID:25787151 PMID:37077353 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054
JBrowse link
G Cyct cytochrome c, testis increases expression EXP Ketoconazole results in increased expression of CYCT mRNA CTD PMID:25787151 NCBI chr 3:61,290,090...61,297,158
Ensembl chr 3:60,913,562...61,297,158
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 increases expression EXP Ketoconazole results in increased expression of CYP11A1 mRNA CTD PMID:26610754 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338
JBrowse link
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 multiple interactions
decreases activity
ISO Ketoconazole binds to and results in decreased activity of CYP11B1 protein
Ketoconazole results in decreased activity of CYP11B1 protein
CTD PMID:15743198 PMID:31982514 NCBI chr 7:106,838,590...106,845,004
Ensembl chr 7:106,838,590...106,845,004
JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 decreases activity
multiple interactions
increases expression
ISO Ketoconazole results in decreased activity of CYP11B2 protein
Ketoconazole binds to and results in decreased activity of CYP11B2 protein; Ketoconazole promotes the reaction [Colforsin results in increased expression of CYP11B2 mRNA]
Ketoconazole results in increased expression of CYP11B2 mRNA
CTD PMID:15743198 PMID:16935330 PMID:31982514 NCBI chr 7:106,808,559...106,814,048
Ensembl chr 7:106,808,559...106,814,048
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases activity
decreases expression
multiple interactions
ISO
EXP
Ketoconazole results in decreased activity of CYP17A1 protein
Ketoconazole results in decreased expression of CYP17A1 mRNA
Ketoconazole inhibits the reaction [Colforsin results in increased expression of CYP17A1 mRNA]
CTD PMID:11118046 PMID:15743198 PMID:15771425 PMID:15934942 PMID:16935330 More... NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 increases activity
decreases expression
multiple interactions
decreases activity
ISO
EXP
Ketoconazole results in increased activity of CYP19A1 protein
Ketoconazole results in decreased expression of CYP19A1 mRNA
[Ketoconazole results in increased activity of CYP19A1 protein] which results in increased chemical synthesis of Estrone; [Ketoconazole results in increased activity of CYP19A1 protein] which results in increased metabolism of Androstenedione
Ketoconazole results in decreased activity of CYP19A1 protein
CTD PMID:20087668 PMID:27159630 PMID:31330226 PMID:36374910 PMID:36653537 NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases activity
increases expression
multiple interactions
decreases activity
ISO
EXP
Ketoconazole results in increased activity of CYP1A1 protein
Ketoconazole results in increased expression of CYP1A1 mRNA
Ketoconazole binds to and results in decreased activity of and results in increased expression of CYP1A1 protein; Ketoconazole results in increased expression of and results in increased activity of CYP1A1 protein
Ketoconazole results in increased expression of CYP1A1 mRNA; Ketoconazole results in increased expression of CYP1A1 protein
Ketoconazole results in decreased activity of CYP1A1 protein
[Ketoconazole results in increased activity of and results in increased localization of AHR protein] which results in increased expression of CYP1A1 mRNA; [Ketoconazole results in increased activity of and results in increased localization of AHR protein] which results in increased expression of CYP1A1 protein; Dactinomycin inhibits the reaction [Ketoconazole results in increased expression of CYP1A1 mRNA]; Ketoconazole binds to and results in decreased activity of and results in increased expression of CYP1A1 protein; Ketoconazole inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; Ketoconazole results in increased expression of and results in increased activity of CYP1A1 protein
[Ketoconazole co-treated with Carbon Tetrachloride] results in increased expression of CYP1A1 mRNA; Ketoconazole inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]
CTD PMID:14709627 PMID:17283379 PMID:18420780 PMID:18493746 PMID:19070657 More... NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
increases expression
decreases activity
ISO
EXP
Ketoconazole affects the reaction [[NADP co-treated with CYP1A2 protein co-treated with CYP2C8 protein co-treated with CYP2C9 protein co-treated with CYP2C19 protein co-treated with CYP2D6 protein co-treated with CYP3A4 protein co-treated with POR protein] results in increased metabolism of 1-(3-(4-phenoxyphenoxy)-2-oxopropyl)indole-5-carboxylic acid]; Ketoconazole inhibits the reaction [CYP1A2 protein results in increased metabolism of Triazines]
Ketoconazole results in increased expression of CYP1A2 mRNA; Ketoconazole results in increased expression of CYP1A2 protein
Ketoconazole results in decreased activity of CYP1A2 protein
Ketoconazole inhibits the reaction [CYP1A2 protein results in increased metabolism of 3-cyano-7-ethoxycoumarin]
Ketoconazole inhibits the reaction [CYP1A2 protein results in increased oxidation of Uroporphyrinogens]
CTD PMID:1567206 PMID:9305587 PMID:12814958 PMID:15618748 PMID:15879494 More... NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity ISO Ketoconazole results in decreased activity of CYP1B1 protein CTD PMID:14709627 PMID:18420780 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 multiple interactions
decreases activity
EXP
ISO
[Ketoconazole co-treated with Calcitriol] results in increased expression of CYP24A1 mRNA; Ketoconazole inhibits the reaction [Calcitriol results in increased activity of CYP24A1 protein]
Ketoconazole inhibits the reaction [Calcifediol results in increased expression of CYP24A1 mRNA]; Ketoconazole promotes the reaction [Calcitriol results in increased expression of CYP24A1 mRNA]
[Ketoconazole results in decreased metabolism of alfacalcidol] which results in decreased expression of CYP24A1 mRNA; [Ketoconazole results in decreased metabolism of Calcitriol] which results in increased expression of CYP24A1 mRNA; Ketoconazole promotes the reaction [Calcitriol results in increased expression of CYP24A1 mRNA]
Ketoconazole results in decreased activity of CYP24A1 protein
CTD PMID:16483768 PMID:16824767 PMID:18840526 PMID:20206692 PMID:26485663 NCBI chr 3:159,275,947...159,290,383
Ensembl chr 3:159,275,947...159,290,383
JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 decreases response to substance
increases expression
decreases activity
multiple interactions
ISO
EXP
Ketoconazole results in decreased susceptibility to CYP26A1 protein
Ketoconazole results in increased expression of CYP26A1 mRNA
Ketoconazole results in decreased activity of CYP26A1; Ketoconazole results in decreased activity of CYP26A1 protein
[[Ketoconazole results in decreased activity of CYP26A1 protein] which results in decreased metabolism of Tretinoin] which results in decreased chemical synthesis of 4-hydroxyretinoic acid; [[Ketoconazole results in decreased activity of CYP26A1 protein] which results in decreased metabolism of Tretinoin] which results in decreased chemical synthesis of 4-oxoretinoic acid; [Ketoconazole results in decreased activity of CYP26A1 protein] which results in decreased chemical synthesis of 4-hydroxyretinoic acid; [Ketoconazole results in decreased activity of CYP26A1 protein] which results in decreased chemical synthesis of 4-oxoretinoic acid; [Ketoconazole results in decreased activity of CYP26A1 protein] which results in decreased metabolism of Tretinoin; Ketoconazole inhibits the reaction [CYP26A1 mRNA results in increased chemical synthesis of 4-hydroxyretinoic acid]; Ketoconazole inhibits the reaction [CYP26A1 mRNA results in increased chemical synthesis of 4-oxoretinoic acid]; Ketoconazole inhibits the reaction [CYP26A1 mRNA results in increased metabolism of 4-oxoretinoic acid]; Ketoconazole inhibits the reaction [CYP26A1 mRNA results in increased metabolism of Tretinoin]; Ketoconazole inhibits the reaction [CYP26A1 protein inhibits the reaction [Tretinoin results in increased activity of FAS protein]]; Ketoconazole inhibits the reaction [CYP26A1 protein inhibits the reaction [Tretinoin results in increased activity of TNF protein]]; Ketoconazole inhibits the reaction [CYP26A1 protein inhibits the reaction [Tretinoin results in increased activity of TNFSF10 protein]]; Ketoconazole inhibits the reaction [CYP26A1 protein results in increased metabolism of and results in decreased susceptibility to Tretinoin]; Ketoconazole inhibits the reaction [CYP26A1 protein results in increased metabolism of Tretinoin]; Ketoconazole inhibits the reaction [CYP26A1 results in increased metabolism of Tretinoin]
CTD PMID:12091498 PMID:14532297 PMID:15703382 PMID:18059332 PMID:21906690 More... NCBI chr 1:235,471,368...235,475,204
Ensembl chr 1:235,471,298...235,475,204
JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 multiple interactions
decreases activity
ISO Ketoconazole inhibits the reaction [CYP26B1 protein results in increased metabolism of Tretinoin]; Ketoconazole inhibits the reaction [CYP26B1 results in increased metabolism of Tretinoin]
Ketoconazole results in decreased activity of CYP26B1
CTD PMID:14532297 PMID:21906690 NCBI chr 4:117,041,808...117,058,628
Ensembl chr 4:117,041,808...117,058,628
JBrowse link
G Cyp26c1 cytochrome P450, family 26, subfamily C, polypeptide 1 multiple interactions ISO Ketoconazole inhibits the reaction [CYP26C1 protein results in increased metabolism of alitretinoin]; Ketoconazole inhibits the reaction [CYP26C1 protein results in increased metabolism of Tretinoin] CTD PMID:21906690 NCBI chr 1:235,458,961...235,468,433
Ensembl chr 1:235,459,356...235,466,842
JBrowse link
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 decreases activity EXP Ketoconazole results in decreased activity of CYP27B1 protein CTD PMID:16483768 NCBI chr 7:62,869,340...62,876,242
Ensembl chr 7:62,871,297...62,876,241
JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 affects expression
decreases activity
increases expression
EXP Ketoconazole affects the expression of CYP2A1 mRNA
Ketoconazole results in decreased activity of CYP2A1 protein
Ketoconazole results in increased expression of CYP2A1 protein
CTD PMID:7986207 PMID:15879494 PMID:18355885 NCBI chr 1:82,231,611...82,244,887
Ensembl chr 1:82,231,611...82,244,887
JBrowse link
G Cyp2a2 cytochrome P450, family 2, subfamily a, polypeptide 2 multiple interactions EXP Ketoconazole inhibits the reaction [CYP2A2 protein results in increased metabolism of 7-benzyloxyquinoline] CTD PMID:19858067 NCBI chr 1:82,263,833...82,289,487
Ensembl chr 1:82,263,833...82,289,487
JBrowse link
G Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 decreases activity ISO Ketoconazole results in decreased activity of CYP2A4 protein CTD PMID:18420780 NCBI chr 1:82,171,914...82,179,980
Ensembl chr 1:82,169,949...82,179,979
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 multiple interactions EXP Ketoconazole inhibits the reaction [CYP2B1 protein results in increased metabolism of 7-benzyloxy-4-trifluoromethylcoumarin] CTD PMID:19858067 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Cyp2b15 cytochrome P450, family 2, subfamily b, polypeptide 15 affects expression EXP Ketoconazole affects the expression of CYP2B15 mRNA CTD PMID:18355885 NCBI chr 1:82,094,188...82,106,492
Ensembl chr 1:82,094,180...82,106,492
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 decreases activity
increases expression
multiple interactions
ISO Ketoconazole results in decreased activity of CYP2B6 protein
Ketoconazole results in decreased activity of CYP2B10 protein
Ketoconazole results in increased expression of CYP2B10 mRNA
Ketoconazole inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP2B6 mRNA]; Ketoconazole inhibits the reaction [Phenobarbital results in increased expression of CYP2B6 mRNA]; Ketoconazole inhibits the reaction [Rifampin results in increased expression of CYP2B6 mRNA]
CTD PMID:14709627 PMID:16608920 PMID:17438109 PMID:17966066 PMID:18420780 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
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G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 multiple interactions
decreases activity
EXP Ketoconazole inhibits the reaction [CYP2C11 protein results in increased metabolism of 7-methoxy-4-trifluoromethylcoumarin]
Ketoconazole results in decreased activity of CYP2C11 protein
CTD PMID:15879494 PMID:19858067 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066
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G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 multiple interactions
decreases activity
EXP
ISO
Ketoconazole inhibits the reaction [CYP2C6V1 protein results in increased metabolism of 7-methoxy-4-trifluoromethylcoumarin]
Ketoconazole results in decreased activity of CYP2C29 protein
Ketoconazole affects the reaction [[NADP co-treated with CYP1A2 protein co-treated with CYP2C8 protein co-treated with CYP2C9 protein co-treated with CYP2C19 protein co-treated with CYP2D6 protein co-treated with CYP3A4 protein co-treated with POR protein] results in increased metabolism of 1-(3-(4-phenoxyphenoxy)-2-oxopropyl)indole-5-carboxylic acid]
Ketoconazole results in decreased activity of CYP2C19 protein
Ketoconazole results in decreased activity of CYP2C6V1 protein
CTD PMID:12814958 PMID:14709627 PMID:15618748 PMID:15879494 PMID:18420780 More... NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
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G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 decreases activity
multiple interactions
ISO Ketoconazole results in decreased activity of CYP2C8 protein
Ketoconazole affects the reaction [[NADP co-treated with CYP1A2 protein co-treated with CYP2C8 protein co-treated with CYP2C9 protein co-treated with CYP2C19 protein co-treated with CYP2D6 protein co-treated with CYP3A4 protein co-treated with POR protein] results in increased metabolism of 1-(3-(4-phenoxyphenoxy)-2-oxopropyl)indole-5-carboxylic acid]
CTD PMID:14709627 PMID:15601807 PMID:24120545
G Cyp2d2 cytochrome P450, family 2, subfamily d, polypeptide 2 multiple interactions EXP Ketoconazole inhibits the reaction [CYP2D2 protein results in increased metabolism of 3-(2-(N,N-diethyl-N-methylammonium)ethyl)-7-methoxy-4-methylcoumarin] CTD PMID:19858067 NCBI chr 7:113,935,138...113,939,209
Ensembl chr 7:113,935,138...113,939,209
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G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 multiple interactions
decreases expression
decreases activity
ISO Ketoconazole affects the reaction [[NADP co-treated with CYP1A2 protein co-treated with CYP2C8 protein co-treated with CYP2C9 protein co-treated with CYP2C19 protein co-treated with CYP2D6 protein co-treated with CYP3A4 protein co-treated with POR protein] results in increased metabolism of 1-(3-(4-phenoxyphenoxy)-2-oxopropyl)indole-5-carboxylic acid]; Ketoconazole inhibits the reaction [CYP2D6 protein results in increased metabolism of YM 758]
Ketoconazole results in decreased expression of CYP2D22 mRNA; Ketoconazole results in decreased expression of CYP2D22 protein
Ketoconazole results in decreased activity of CYP2D22 protein; Ketoconazole results in decreased activity of CYP2D6 protein
Ketoconazole inhibits the reaction [CYP2D22 protein results in increased metabolism of Dextromethorphan]; Ketoconazole inhibits the reaction [Maneb results in decreased expression of CYP2D22 protein]; Ketoconazole inhibits the reaction [Nicotine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of CYP2D22 mRNA]]; Ketoconazole inhibits the reaction [Nicotine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of CYP2D22 protein]]; Ketoconazole inhibits the reaction [Nicotine results in increased expression of CYP2D22 mRNA]; Ketoconazole inhibits the reaction [Nicotine results in increased expression of CYP2D22 protein]; Ketoconazole inhibits the reaction [Paraquat results in decreased expression of CYP2D22 protein]; Ketoconazole promotes the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of CYP2D22 mRNA]; Ketoconazole promotes the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of CYP2D22 protein]; Nicotine inhibits the reaction [Ketoconazole results in decreased expression of CYP2D22 mRNA]; Nicotine inhibits the reaction [Ketoconazole results in decreased expression of CYP2D22 protein]
CTD PMID:15618748 PMID:16595712 PMID:18420780 PMID:19230594 PMID:19594327 More... NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
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G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases activity ISO Ketoconazole results in decreased activity of CYP2E1 protein CTD PMID:15618748 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
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G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 decreases activity ISO Ketoconazole results in decreased activity of CYP2J2 protein CTD PMID:12851038 NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794
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G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions
decreases expression
increases response to substance
decreases activity
increases expression
increases metabolic processing
EXP
ISO
Ketoconazole inhibits the reaction [CYP3A2 protein results in increased metabolism of 7-benzyloxyquinoline]; Ketoconazole inhibits the reaction [Phenytoin results in increased expression of CYP3A2 protein]
Ketoconazole results in decreased expression of CYP3A4 mRNA; Ketoconazole results in decreased expression of CYP3A4 protein
CYP3A4 protein results in increased susceptibility to Ketoconazole
Ketoconazole results in decreased activity of CYP3A2 protein; Ketoconazole results in decreased activity of CYP3A4 protein
Ketoconazole results in increased expression of CYP3A4 mRNA
CYP3A4 protein results in increased metabolism of Ketoconazole
[Ketoconazole inhibits the reaction [CYP3A4 protein results in increased susceptibility to Amodiaquine]] which results in decreased expression of BCL2 protein; [Ketoconazole inhibits the reaction [CYP3A4 protein results in increased susceptibility to Amodiaquine]] which results in decreased expression of MCL1 protein; [Ketoconazole inhibits the reaction [CYP3A4 protein results in increased susceptibility to Amodiaquine]] which results in increased expression of BAX protein; [Ketoconazole results in decreased activity of CYP3A4 protein] which results in decreased chemical synthesis of 1-hydroxymethylmidazolam; [Ketoconazole results in decreased activity of CYP3A4 protein] which results in decreased degradation of vanoxerine; [Ketoconazole results in decreased activity of CYP3A4 protein] which results in decreased hydroxylation of Midazolam; [Ketoconazole results in decreased activity of CYP3A4 protein] which results in decreased metabolism of Midazolam; [Ketoconazole results in decreased activity of CYP3A4 protein] which results in decreased metabolism of Testosterone; [Ketoconazole results in decreased activity of CYP3A4 protein] which results in decreased metabolism of Triazolam; Ketoconazole affects the reaction [[NADP co-treated with CYP1A2 protein co-treated with CYP2C8 protein co-treated with CYP2C9 protein co-treated with CYP2C19 protein co-treated with CYP2D6 protein co-treated with CYP3A4 protein co-treated with POR protein] results in increased metabolism of 1-(3-(4-phenoxyphenoxy)-2-oxopropyl)indole-5-carboxylic acid]; Ketoconazole affects the reaction [CYP3A4 polymorphism affects the metabolism of cabozantinib]; Ketoconazole affects the reaction [CYP3A4 protein alternative form affects the metabolism of acalabrutinib]; Ketoconazole affects the reaction [CYP3A4 protein alternative form affects the metabolism of vandetanib]; Ketoconazole binds to and results in decreased activity of CYP3A4 protein; Ketoconazole inhibits the reaction [3,3'-diindolylmethane results in increased expression of CYP3A4 mRNA]; Ketoconazole inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP3A4 mRNA]; Ketoconazole inhibits the reaction [[2,3,5,4'-tetrahydroxystilbene-2-O-beta-D-glucopyranoside co-treated with NADP] results in decreased activity of CYP3A4 protein]; Ketoconazole inhibits the reaction [[Amiodarone co-treated with CYP3A4 protein] results in increased expression of CXCL8 mRNA]; Ketoconazole inhibits the reaction [[Amiodarone co-treated with CYP3A4 protein] results in increased expression of TNF mRNA]; Ketoconazole inhibits the reaction [[CYP3A4 protein co-treated with GSTP1 protein co-treated with Glutathione] results in increased abundance of 2'-(glutathion-S-yl)-deschlorodiclofenac]; Ketoconazole inhibits the reaction [[CYP3A4 protein co-treated with GSTP1 protein co-treated with Glutathione] results in increased abundance of 5-hydroxydiclofenac]; Ketoconazole inhibits the reaction [[CYP3A4 protein results in increased hydroxylation of Testosterone] which results in increased chemical synthesis of 6 beta-hydroxytestosterone]; Ketoconazole inhibits the reaction [[CYP3A4 protein results in increased hydroxylation of Testosterone] which results in increased chemical synthesis of Hydroxytestosterones]; Ketoconazole inhibits the reaction [[desethylamiodarone co-treated with CYP3A4 protein] results in increased expression of CXCL8 mRNA]; Ketoconazole inhibits the reaction [[desethylamiodarone co-treated with CYP3A4 protein] results in increased expression of TNF mRNA]; Ketoconazole inhibits the reaction [Calcitriol results in increased expression of CYP3A4 protein]; Ketoconazole inhibits the reaction [Corticosterone promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]]; Ketoconazole inhibits the reaction [Corticosterone results in increased expression of CYP3A4 mRNA]; Ketoconazole inhibits the reaction [CYP3A4 protein affects the metabolism of Endosulfan]; Ketoconazole inhibits the reaction [CYP3A4 protein affects the metabolism of Mefloquine]; Ketoconazole inhibits the reaction [CYP3A4 protein promotes the reaction [Oxygen deficiency results in increased expression of EPO mRNA]]; Ketoconazole inhibits the reaction [CYP3A4 protein promotes the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]]; Ketoconazole inhibits the reaction [CYP3A4 protein results in decreased abundance of Midazolam]; Ketoconazole inhibits the reaction [CYP3A4 protein results in decreased methylation of adinazolam]; Ketoconazole inhibits the reaction [CYP3A4 protein results in decreased methylation of mono-N-demethyladinazolam]; Ketoconazole inhibits the reaction [CYP3A4 protein results in decreased susceptibility to Docetaxel]; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased abundance of 1-hydroxymethylmidazolam]; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased chemical synthesis of 1-hydroxymethylmidazolam]; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased chemical synthesis of 11,12-epoxy-5,8,14-eicosatrienoic acid]; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased chemical synthesis of 14,15-epoxy-5,8,11-eicosatrienoic acid]; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased chemical synthesis of 3'-p-hydroxypaclitaxel]; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased chemical synthesis of 4-hydroxymidazolam]; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased chemical synthesis of 5,6-epoxy-8,11,14-eicosatrienoic acid]; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased chemical synthesis of 6 beta-hydroxytestosterone]; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased chemical synthesis of 8,9-epoxyeicosatrienoic acid]; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased chemical synthesis of clozapine N-oxide]; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased chemical synthesis of norclozapine]; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased degradation of Clopidogrel]; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased degradation of Ticlopidine]; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased glutathionylation of dauricine]; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased hydrolysis of Testosterone]; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Carbofuran]; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Cholecalciferol]; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Metoprolol]; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Midazolam]; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased hydroxylation of mono-N-desethylamiodarone]; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased hydroxylation of nefazodone]; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Nifedipine]; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Testosterone]; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased metabolism of 8-epidiosbulbin E acetate]; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased metabolism of and results in decreased abundance of Quetiapine Fumarate]; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased metabolism of Arachidonic Acid]; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased metabolism of bufalin]; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased metabolism of bufogenin]; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased metabolism of cabozantinib]; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased metabolism of carbosulfan]; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased metabolism of cinobufagin]; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased metabolism of eldecalcitol]; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased metabolism of Felodipine]; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased metabolism of laquinimod]; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased metabolism of Midazolam]; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased metabolism of Terfenadine]; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased metabolism of Testosterone]; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased metabolism of Triazolam]; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased metabolism of YM 758]; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased oxidation of 2-oxo-clopidogrel]; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased oxidation of 7-benzyloxy-4-trifluoromethylcoumarin]; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased oxidation of dimemorfan]; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased oxidation of Lithocholic Acid]; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased oxidation of Nifedipine]; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased oxidation of Paclitaxel]; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased susceptibility to Amodiaquine]; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased susceptibility to Clopidogrel]; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased susceptibility to Endosulfan]; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased susceptibility to Ticlopidine]; Ketoconazole inhibits the reaction [erdafitinib results in decreased activity of CYP3A4 protein]; Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [piperine results in increased expression of CYP3A4 mRNA]]; Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [piperine results in increased expression of CYP3A4 protein]]; Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]]; Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP3A4 protein]]; Ketoconazole inhibits the reaction [Paclitaxel results in increased expression of CYP3A4 mRNA]; Ketoconazole inhibits the reaction [Paclitaxel results in increased expression of CYP3A4 protein]; Ketoconazole inhibits the reaction [Phenobarbital results in increased expression of CYP3A4 mRNA]; Ketoconazole inhibits the reaction [Rifampin promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]]; Ketoconazole inhibits the reaction [Rifampin results in increased activity of CYP3A4 protein]; Ketoconazole inhibits the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; Ketoconazole inhibits the reaction [Rifampin results in increased expression of CYP3A4 protein]; Ketoconazole inhibits the reaction [U 0126 affects the activity of CYP3A4 protein]; Ketoconazole results in increased expression of and results in decreased activity of CYP3A4 protein
CTD PMID:9600717 PMID:10952769 PMID:10997946 PMID:11377097 PMID:11502731 More... NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 multiple interactions
decreases activity
affects expression
EXP [Strychnine co-treated with Ketoconazole] results in decreased expression of CYP3A23-3A1 protein; Ketoconazole inhibits the reaction [CYP3A23-3A1 protein results in increased metabolism of 7-benzyloxyquinoline]; Ketoconazole inhibits the reaction [Genistein results in increased expression of CYP3A23-3A1 mRNA]
Ketoconazole results in decreased activity of CYP3A23-3A1 protein
Ketoconazole affects the expression of CYP3A23-3A1 mRNA
CTD PMID:12814958 PMID:15879494 PMID:18355885 PMID:19858067 PMID:32185415 More... NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
Ensembl chr12:9,254,475...9,285,030
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 multiple interactions
affects response to substance
decreases activity
ISO CYP3A5 gene polymorphism affects the reaction [Ketoconazole results in decreased metabolism of Tacrolimus]; Ketoconazole inhibits the reaction [Beclomethasone results in increased expression of CYP3A5 mRNA]; Ketoconazole inhibits the reaction [Budesonide results in increased expression of CYP3A5 mRNA]; Ketoconazole inhibits the reaction [CYP3A5 protein affects the metabolism of Alfentanil]; Ketoconazole inhibits the reaction [CYP3A5 protein results in increased hydroxylation of Testosterone]; Ketoconazole inhibits the reaction [CYP3A5 protein results in increased oxidation of Lithocholic Acid]; Ketoconazole inhibits the reaction [erdafitinib results in decreased activity of CYP3A5 protein]; Ketoconazole inhibits the reaction [flunisolide results in increased expression of CYP3A5 mRNA]; Ketoconazole inhibits the reaction [Fluticasone results in increased expression of CYP3A5 mRNA]; Ketoconazole inhibits the reaction [Triamcinolone Acetonide results in increased expression of CYP3A5 mRNA]
CYP3A5 gene polymorphism affects the susceptibility to Ketoconazole
Ketoconazole results in decreased activity of CYP3A5 protein
CTD PMID:15557344 PMID:15731592 PMID:19384264 PMID:24555085 PMID:26302866 More... NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
JBrowse link
G Cyp4b1 cytochrome P450, family 4, subfamily b, polypeptide 1 increases expression EXP Ketoconazole results in increased expression of CYP4B1 mRNA CTD PMID:37077353 NCBI chr 5:129,139,019...129,176,860
Ensembl chr 5:129,139,038...129,156,348
JBrowse link
G Cyp4f1 cytochrome P450, family 4, subfamily f, polypeptide 1 decreases activity
affects expression
ISO
EXP
Ketoconazole results in decreased activity of CYP4F12 protein
Ketoconazole affects the expression of CYP4F2 mRNA
CTD PMID:14709627 PMID:18355885 NCBI chr 7:12,010,850...12,022,497
Ensembl chr 7:12,010,852...12,022,046
JBrowse link
G Cyp51 cytochrome P450, family 51 decreases activity
increases expression
decreases response to substance
multiple interactions
increases activity
ISO
EXP