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Gene: Hpn (hepsin) Rattus norvegicus
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Symbol: Hpn
Name: hepsin
Description: Predicted to have calcium-activated potassium channel activity and serine-type endopeptidase activity. Predicted to be involved in several processes, including cholesterol homeostasis; positive regulation of nitrogen compound metabolic process; and regulation of epithelial cell proliferation. Predicted to colocalize with the nuclear membrane. Orthologous to human HPN (hepsin); INTERACTS WITH (+)-schisandrin B; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: hepsin (transmembrane protease, serine 1); serine protease hepsin
Orthologs:
Homo sapiens (human) : HPN (hepsin)  HGNC  Alliance
Mus musculus (house mouse) : Hpn (hepsin)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hpn (hepsin)
Pan paniscus (bonobo/pygmy chimpanzee) : HPN (hepsin)
Canis lupus familiaris (dog) : HPN (hepsin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hpn (hepsin)
Sus scrofa (pig) : HPN (hepsin)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0189,534,112 - 89,549,575 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0190,688,659 - 90,704,122 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4186,145,615 - 86,161,091 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1186,223,725 - 86,239,202 (-)NCBI
Celera180,705,987 - 80,721,634 (-)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Hpn
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 61982
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.