Dlc1 (DLC1 Rho GTPase activating protein) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Dlc1 (DLC1 Rho GTPase activating protein) Rattus norvegicus
Analyze
Symbol: Dlc1
Name: DLC1 Rho GTPase activating protein
RGD ID: 68416
Description: Exhibits GTPase activator activity; phospholipase binding activity; and vinculin binding activity. Involved in activation of phospholipase C activity; cellular response to insulin stimulus; and cytoskeleton organization. Localizes to membrane raft. Colocalizes with actin filament; focal adhesion; and stress fiber. Human ortholog(s) of this gene implicated in colorectal cancer. Orthologous to human DLC1 (DLC1 Rho GTPase activating protein); PARTICIPATES IN Rho/Rac/Cdc42 mediated signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Arhgap7; deleted in liver cancer 1; deleted in liver cancer 1 protein homolog; dlc-1; p122-RhoGAP; rho GTPase activating protein 7; rho GTPase-activating protein 7; rho-type GTPase-activating protein 7; RhoGAP; stAR-related lipid transfer protein 12; stARD12; START domain-containing protein 12
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21655,246,716 - 55,671,441 (+)NCBI
Rnor_6.0 Ensembl1659,077,574 - 59,247,754 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01658,776,489 - 59,247,752 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01658,638,567 - 58,928,425 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41659,312,930 - 59,355,129 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11659,313,004 - 59,355,204 (+)NCBI
Celera1653,351,212 - 53,453,368 (+)NCBICelera
Celera1653,685,682 - 53,727,187 (+)NCBICelera
Cytogenetic Map16q12.1-q12.2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (ISO)
1-nitropyrene  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrobenzenesulfonic acid  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
acrolein  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
ammonium chloride  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
cadmium atom  (ISO)
carbon nanotube  (ISO)
chloroprene  (EXP,ISO)
ciglitazone  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (ISO)
CU-O LINKAGE  (ISO)
cumene  (ISO)
cyclophosphamide  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
ethanol  (ISO)
flutamide  (EXP)
formaldehyde  (ISO)
genistein  (EXP)
glycidol  (EXP)
indometacin  (ISO)
irinotecan  (ISO)
iron atom  (EXP)
iron(0)  (EXP)
leflunomide  (ISO)
mercury dibromide  (ISO)
methotrexate  (ISO)
methoxychlor  (EXP)
methylmercury chloride  (ISO)
methylseleninic acid  (ISO)
mifepristone  (ISO)
nefazodone  (EXP)
nickel atom  (ISO)
ozone  (ISO)
panobinostat  (ISO)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
progesterone  (ISO)
propiconazole  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
tetrachloromethane  (ISO)
titanium dioxide  (ISO)
topotecan  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
triptonide  (ISO)
troglitazone  (ISO)
ursodeoxycholic acid  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
actin filament  (IDA)
caveola  (IEA,ISO)
cortical actin cytoskeleton  (IEA,ISO)
cytoplasm  (IEA,ISO)
cytosol  (IEA,ISO)
focal adhesion  (IDA,IEA,ISO)
membrane  (IEA)
membrane raft  (IBA,IDA)
nucleus  (IEA,ISO)
ruffle membrane  (IEA,ISO)
stress fiber  (IDA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:10364218   PMID:12545165   PMID:15710412   PMID:16641100   PMID:16951145   PMID:17190795   PMID:17292327   PMID:17888903   PMID:17932950   PMID:19158340   PMID:19692654  


Genomics

Comparative Map Data
Dlc1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21655,246,716 - 55,671,441 (+)NCBI
Rnor_6.0 Ensembl1659,077,574 - 59,247,754 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01658,776,489 - 59,247,752 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01658,638,567 - 58,928,425 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41659,312,930 - 59,355,129 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11659,313,004 - 59,355,204 (+)NCBI
Celera1653,351,212 - 53,453,368 (+)NCBICelera
Celera1653,685,682 - 53,727,187 (+)NCBICelera
Cytogenetic Map16q12.1-q12.2NCBI
DLC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl813,083,361 - 13,604,610 (-)EnsemblGRCh38hg38GRCh38
GRCh38813,083,361 - 13,604,620 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37812,940,870 - 13,462,129 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36812,985,243 - 13,416,766 (-)NCBINCBI36hg18NCBI36
Build 34812,985,242 - 13,416,766NCBI
Celera811,906,167 - 12,337,728 (-)NCBI
Cytogenetic Map8p22NCBI
HuRef811,483,338 - 11,914,734 (-)NCBIHuRef
CHM1_1813,142,556 - 13,574,157 (-)NCBICHM1_1
Dlc1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39837,034,893 - 37,420,343 (-)NCBIGRCm39mm39
GRCm39 Ensembl837,034,905 - 37,420,297 (-)Ensembl
GRCm38836,567,739 - 36,953,184 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl836,567,751 - 36,953,143 (-)EnsemblGRCm38mm10GRCm38
MGSCv37837,630,799 - 37,676,928 (-)NCBIGRCm37mm9NCBIm37
MGSCv36837,630,799 - 37,676,928 (-)NCBImm8
Celera839,196,115 - 39,243,125 (-)NCBICelera
Cytogenetic Map8A4NCBI
cM Map823.05NCBI
Dlc1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554633,598,985 - 3,990,849 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554633,599,415 - 3,981,187 (+)NCBIChiLan1.0ChiLan1.0
DLC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.189,037,742 - 9,087,819 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl89,037,742 - 9,460,233 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0812,282,190 - 12,809,770 (-)NCBIMhudiblu_PPA_v0panPan3
DLC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11636,531,754 - 36,943,033 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1636,531,754 - 36,943,033 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1636,996,594 - 37,413,641 (-)NCBI
ROS_Cfam_1.01638,571,399 - 39,066,161 (-)NCBI
UMICH_Zoey_3.11636,670,048 - 37,080,683 (-)NCBI
UNSW_CanFamBas_1.01637,232,627 - 37,643,411 (-)NCBI
UU_Cfam_GSD_1.01637,352,432 - 37,763,946 (-)NCBI
Dlc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494342,192,682 - 42,649,385 (+)NCBI
SpeTri2.0NW_0049365732,493,051 - 2,658,396 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DLC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl171,170,195 - 1,637,162 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1171,169,709 - 1,637,171 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
DLC1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1811,211,230 - 11,632,278 (-)NCBI
Dlc1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248393,495,580 - 3,899,009 (+)NCBI

Position Markers
D16Rat62  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21655,340,915 - 55,341,087 (+)MAPPER
Rnor_6.01658,825,899 - 58,826,070NCBIRnor6.0
Rnor_5.01658,513,569 - 58,513,740UniSTSRnor5.0
RGSC_v3.41659,025,441 - 59,025,613RGDRGSC3.4
RGSC_v3.41659,025,442 - 59,025,613UniSTSRGSC3.4
RGSC_v3.11659,025,516 - 59,025,688RGD
Celera1653,399,318 - 53,399,489UniSTS
RH 3.4 Map16555.0UniSTS
RH 3.4 Map16555.0RGD
RH 2.0 Map16642.7RGD
Cytogenetic Map16q12.2UniSTS
D16Nkg55  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21655,639,526 - 55,639,662 (+)MAPPER
Rnor_6.01659,217,121 - 59,217,256NCBIRnor6.0
Rnor_5.01658,897,792 - 58,897,927UniSTSRnor5.0
RGSC_v3.41659,324,618 - 59,324,753UniSTSRGSC3.4
Celera1653,697,132 - 53,697,267UniSTS
Cytogenetic Map16q12.2UniSTS
D16Nkg54  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21655,636,014 - 55,636,207 (+)MAPPER
Rnor_6.01659,213,607 - 59,213,799NCBIRnor6.0
Rnor_5.01658,894,278 - 58,894,470UniSTSRnor5.0
RGSC_v3.41659,321,104 - 59,321,296UniSTSRGSC3.4
Celera1653,693,618 - 53,693,810UniSTS
Cytogenetic Map16q12.2UniSTS
D16Nkg56  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21655,647,980 - 55,648,294 (+)MAPPER
Rnor_6.01659,224,295 - 59,224,608NCBIRnor6.0
Rnor_5.01658,904,966 - 58,905,279UniSTSRnor5.0
RGSC_v3.41659,333,437 - 59,333,750UniSTSRGSC3.4
Celera1653,705,495 - 53,705,808UniSTS
Cytogenetic Map16q12.2UniSTS
BE112293  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21655,554,880 - 55,555,051 (+)MAPPER
Rnor_6.01659,124,179 - 59,124,349NCBIRnor6.0
Rnor_5.01658,805,475 - 58,805,645UniSTSRnor5.0
RGSC_v3.41659,239,854 - 59,240,024UniSTSRGSC3.4
Celera1653,613,006 - 53,613,176UniSTS
RH 3.4 Map16556.9UniSTS
Cytogenetic Map16q12.2UniSTS
AI176713  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21655,671,074 - 55,671,197 (+)MAPPER
Rnor_6.01659,247,388 - 59,247,510NCBIRnor6.0
Rnor_5.01658,928,059 - 58,928,181UniSTSRnor5.0
RGSC_v3.41659,356,530 - 59,356,652UniSTSRGSC3.4
Celera1653,728,588 - 53,728,710UniSTS
RH 3.4 Map16546.3UniSTS
Cytogenetic Map16q12.2UniSTS
AI104472  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21655,494,837 - 55,494,935 (+)MAPPER
Rnor_6.01659,064,098 - 59,064,195NCBIRnor6.0
Rnor_5.01658,745,665 - 58,745,762UniSTSRnor5.0
RGSC_v3.41659,178,965 - 59,179,062UniSTSRGSC3.4
Celera1653,553,045 - 53,553,142UniSTS
RH 3.4 Map16545.8UniSTS
Cytogenetic Map16q12.2UniSTS
BF402825  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21655,658,328 - 55,658,453 (+)MAPPER
Rnor_6.01659,234,642 - 59,234,766NCBIRnor6.0
Rnor_5.01658,915,313 - 58,915,437UniSTSRnor5.0
RGSC_v3.41659,343,784 - 59,343,908UniSTSRGSC3.4
Celera1653,715,842 - 53,715,966UniSTS
RH 3.4 Map16557.1UniSTS
Cytogenetic Map16q12.2UniSTS
BI302233  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21655,403,364 - 55,403,578 (+)MAPPER
Rnor_6.01658,972,708 - 58,972,921NCBIRnor6.0
Rnor_5.01658,654,484 - 58,654,697UniSTSRnor5.0
RGSC_v3.41659,087,542 - 59,087,755UniSTSRGSC3.4
Celera1653,461,600 - 53,461,813UniSTS
RH 3.4 Map16545.5UniSTS
Cytogenetic Map16q12.2UniSTS
BG374117  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21655,450,039 - 55,450,193 (+)MAPPER
Rnor_6.01659,019,217 - 59,019,370NCBIRnor6.0
Rnor_5.01658,700,993 - 58,701,146UniSTSRnor5.0
RGSC_v3.41659,134,217 - 59,134,370UniSTSRGSC3.4
Celera1653,508,277 - 53,508,430UniSTS
RH 3.4 Map16558.8UniSTS
Cytogenetic Map16q12.2UniSTS
MARC_21337-21338:1023126946:1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21655,667,766 - 55,668,859 (+)MAPPER
Rnor_6.01659,244,080 - 59,245,172NCBIRnor6.0
Rnor_5.01658,924,751 - 58,925,843UniSTSRnor5.0
RGSC_v3.41659,353,222 - 59,354,314UniSTSRGSC3.4
Celera1653,725,280 - 53,726,372UniSTS
Cytogenetic Map16q12.2UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1600378Arunc4Aerobic running capacity QTL 40.03exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)16109005486162972Rat
2312660Bw95Body weight QTL 950.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)16155018763210301Rat
2312663Slep9Serum leptin concentration QTL 90.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)16155018763210301Rat
2312666Insul16Insulin level QTL 160.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)16155018763210301Rat
2312669Stl23Serum triglyceride level QTL 230.01blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)16155018763210301Rat
737826Alc11Alcohol consumption QTL 113.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16501380264012784Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor depth of invasion (CMO:0001888)161939818770590230Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor depth of invasion (CMO:0001888)161939818770590230Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor diameter (CMO:0001889)161939818770590230Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor diameter (CMO:0001889)161939818770590230Rat
70215Niddm29Non-insulin dependent diabetes mellitus QTL 293.54blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)162075555680316424Rat
2302057Pia29Pristane induced arthritis QTL 293.60.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)162484654169846541Rat
8694453Bw172Body weight QTL 1728.330.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)162751998072519980Rat
6903294Stl30Serum triglyceride level QTL 302.60.0013blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)162834031573340315Rat
1298529Arunc1Aerobic running capacity QTL 14exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)163530711063909364Rat
1578768Stresp22Stress response QTL 222.8thymus mass (VT:0004954)thymus wet weight (CMO:0000855)163900002184000021Rat
2300163Bmd64Bone mineral density QTL 645.30.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)164151271086512710Rat
2293690Bss45Bone structure and strength QTL 455.130.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)164151271086512710Rat
7205510Activ5Activity QTL 53.780.00028locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)164655818890668790Rat
7411648Foco22Food consumption QTL 22150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)165781635790668790Rat
8694429Bw164Body weight QTL 16450.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)165781635790668790Rat
8694364Abfw7Abdominal fat weight QTL 712.220.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)165781635790668790Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:80
Count of miRNA genes:62
Interacting mature miRNAs:75
Transcripts:ENSRNOT00000014924
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 42 34 24 6 24 1 1 34 24 34 11 1
Low 3 1 23 17 13 17 7 10 40 11 7 7
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000014924   ⟹   ENSRNOP00000014923
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1659,197,367 - 59,247,754 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000090477   ⟹   ENSRNOP00000075006
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1659,077,574 - 59,246,106 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000093272
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1659,240,670 - 59,241,143 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000093501
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1659,236,443 - 59,236,932 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000093614
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1659,242,819 - 59,244,581 (+)Ensembl
RefSeq Acc Id: NM_001127446   ⟹   NP_001120918
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21655,627,913 - 55,669,674 (+)NCBI
Rnor_6.01659,197,367 - 59,245,987 (+)NCBI
Rnor_5.01658,638,567 - 58,928,425 (+)NCBI
RGSC_v3.41659,312,930 - 59,355,129 (+)RGD
Celera1653,685,682 - 53,727,187 (+)RGD
Sequence:
RefSeq Acc Id: NM_001370997   ⟹   NP_001357926
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21655,291,584 - 55,671,439 (+)NCBI
RefSeq Acc Id: XM_017587587   ⟹   XP_017443076
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera1653,351,212 - 53,453,368 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017600235   ⟹   XP_017455724
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01658,776,997 - 59,247,752 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017600236   ⟹   XP_017455725
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21655,291,153 - 55,671,441 (+)NCBI
Rnor_6.01658,776,489 - 59,247,752 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017600237   ⟹   XP_017455726
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01658,776,993 - 59,233,238 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039094797   ⟹   XP_038950725
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21655,246,716 - 55,671,441 (+)NCBI
RefSeq Acc Id: XM_039094798   ⟹   XP_038950726
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21655,508,504 - 55,671,439 (+)NCBI
RefSeq Acc Id: XM_039094799   ⟹   XP_038950727
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21655,628,977 - 55,671,441 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_001120918   ⟸   NM_001127446
- Peptide Label: isoform 2
- UniProtKB: G3V7H1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017443076   ⟸   XM_017587587
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_017455725   ⟸   XM_017600236
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017455726   ⟸   XM_017600237
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017455724   ⟸   XM_017600235
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000014923   ⟸   ENSRNOT00000014924
RefSeq Acc Id: ENSRNOP00000075006   ⟸   ENSRNOT00000090477
RefSeq Acc Id: XP_038950725   ⟸   XM_039094797
- Peptide Label: isoform X1
RefSeq Acc Id: NP_001357926   ⟸   NM_001370997
- Peptide Label: isoform 1
RefSeq Acc Id: XP_038950726   ⟸   XM_039094798
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038950727   ⟸   XM_039094799
- Peptide Label: isoform X3
Protein Domains
Rho-GAP   SAM   START

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700128
Promoter ID:EPDNEW_R10652
Type:initiation region
Name:Dlc1_2
Description:DLC1 Rho GTPase activating protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R10653  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01659,077,809 - 59,077,869EPDNEW
RGD ID:13700129
Promoter ID:EPDNEW_R10653
Type:multiple initiation site
Name:Dlc1_1
Description:DLC1 Rho GTPase activating protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R10652  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01659,197,343 - 59,197,403EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Damaging Variants


Assembly: Rnor_5.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
16 58913996 58913997 C A snv Crl:SD (UDEL), KFRS3B/Kyo (KyushuU), SDLEF7/Barth (UDEL), HWY/Slc (KyushuU), IS/Kyo (KyushuU), LE/OrlBarth (UDEL), F344/DuCrlCrlj (KyushuU), LEC/Tj (KyushuU), IS-Tlk/Kyo (KyushuU)
16 58914025 58914026 T G snv LE/OrlBarth (UDEL), SDLEF7/Barth (UDEL), LEC/Tj (KyushuU), IS-Tlk/Kyo (KyushuU), F344/DuCrlCrlj (KyushuU), IS/Kyo (KyushuU), Crl:SD (UDEL)
16 58914029 58914030 C T snv LEC/Tj (KyushuU), Crl:SD (UDEL), SDLEF7/Barth (UDEL), IS-Tlk/Kyo (KyushuU), LE/OrlBarth (UDEL), F344/DuCrlCrlj (KyushuU), IS/Kyo (KyushuU)
16 58914031 58914032 C T snv F344/DuCrlCrlj (KyushuU), LE/OrlBarth (UDEL), IS/Kyo (KyushuU), SDLEF7/Barth (UDEL), LEC/Tj (KyushuU), Crl:SD (UDEL), IS-Tlk/Kyo (KyushuU)
16 58914044 58914045 C T snv LEC/Tj (KyushuU), IS-Tlk/Kyo (KyushuU), Crl:SD (UDEL), F344/DuCrlCrlj (KyushuU), LE/OrlBarth (UDEL), IS/Kyo (KyushuU)
16 58922228 58922229 C T snv SDLEF7/Barth (UDEL), IS-Tlk/Kyo (KyushuU), Crl:SD (UDEL), NIG-III/Hok (KyushuU)


Assembly: Rnor_6.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
16 58791393 58791394 G A snv LH/MavRrrc (RGD), SHRSP/Gcrc (RGD), MHS/Gib (RGD), M520/N (MCW), GK/Ox (RGD), SR/JrHsd (RGD)
16 58791789 58791790 G A snv BBDP/Wor (RGD), MNS/Gib (RGD), Buf/N (MCW)


Assembly: RGSC_v3.4

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
16 59342467 59342468 C A snv BN/SsN (KNAW)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:68416 AgrOrtholog
Ensembl Genes ENSRNOG00000010780 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000014923 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000075006 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000014924 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000090477 UniProtKB/TrEMBL
Gene3D-CATH 1.10.555.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.530.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro DLC1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rho_GTPase_activation_prot UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RhoGAP_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAM/pointed_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  START-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  START_lipid-bd_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:58834 UniProtKB/TrEMBL
NCBI Gene 58834 ENTREZGENE
PANTHER PTHR12659:SF2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam RhoGAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAM_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  START UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Dlc1 PhenoGen
PROSITE RHOGAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  START UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART RhoGAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  START UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47769 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF48350 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2K9I2_RAT UniProtKB/TrEMBL
  G3V7H1 ENTREZGENE, UniProtKB/TrEMBL
  Q63744 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-06-25 Dlc1  DLC1 Rho GTPase activating protein  Dlc1  deleted in liver cancer 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-03-05 Dlc1  deleted in liver cancer 1  Arhgap7  rho GTPase activating protein 7  Symbol and Name updated to reflect Human and Mouse nomenclature 625702 APPROVED
2002-06-10 Arhgap7  rho GTPase activating protein 7      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference