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Gene: Kcnh2 (potassium voltage-gated channel subfamily H member 2) Rattus norvegicus
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Symbol: Kcnh2
Name: potassium voltage-gated channel subfamily H member 2
Description: Exhibits inward rectifier potassium channel activity and scaffold protein binding activity. Involved in central nervous system development; potassium ion transport; and regulation of membrane potential. Localizes to integral component of plasma membrane. Human ortholog(s) of this gene implicated in long QT syndrome; long QT syndrome 2; and short QT syndrome. Orthologous to human KCNH2 (potassium voltage-gated channel subfamily H member 2); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; INTERACTS WITH 17alpha-ethynylestradiol; ammonium chloride; amphetamine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: eag-related protein 1; ERG-1; ERG1; ether-a-go-go-related gene potassium channel 1; ether-a-go-go-related protein 1; potassium channel, voltage gated eag related subfamily H, member 2; potassium voltage-gated channel, subfamily H (eag-related), member 2; r-ERG; RERG; voltage-gated potassium channel subunit Kv11.1
Orthologs:
Homo sapiens (human) : KCNH2 (potassium voltage-gated channel subfamily H member 2)  HGNC  Alliance
Mus musculus (house mouse) : Kcnh2 (potassium voltage-gated channel, subfamily H (eag-related), member 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kcnh2 (potassium voltage-gated channel subfamily H member 2)
Pan paniscus (bonobo/pygmy chimpanzee) : KCNH2 (potassium voltage-gated channel subfamily H member 2)
Canis lupus familiaris (dog) : KCNH2 (potassium voltage-gated channel subfamily H member 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kcnh2 (potassium voltage-gated channel subfamily H member 2)
Sus scrofa (pig) : KCNH2 (potassium voltage-gated channel subfamily H member 2)
Chlorocebus sabaeus (African green monkey) : KCNH2 (potassium voltage-gated channel subfamily H member 2)
Heterocephalus glaber (naked mole-rat) : Kcnh2 (potassium voltage-gated channel subfamily H member 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.047,355,066 - 7,387,282 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl47,355,574 - 7,387,253 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.047,366,726 - 7,398,606 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.446,192,644 - 6,224,285 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.146,192,643 - 6,224,284 (+)NCBI
Celera46,444,570 - 6,473,521 (+)NCBICelera
Cytogenetic Map4q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
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Strain Sequence Variants (Rnor 6.0)