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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621414
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Kcnh2
Name: potassium voltage-gated channel subfamily H member 2
Acc ID: CHEBI:44107
Term: malachite green cation
Definition: An iminium ion obtained by dimethylation of the imino group of 4-{[4-(dimethylamino)phenyl](phenyl)methylene}cyclohexa-2,5-dien-1-imine. Used in the form of its chloride salt as a green-coloured dye.
Chemical ID: MESH:C005095
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Kcnh2decreases activityISORGD:7321016480464CTDmalachite green results in decreased activity of KCNH2 protein

PMID:21362439
Kcnh2multiple interactionsISORGD:7321016480464CTD[malachite green results in decreased activity of KCNH2 protein] which results in decreased import of Thallium

PMID:21362439
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