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GENE - TERM ANNOTATION REPORT

RGD ID: 621414
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Kcnh2
Name: potassium voltage-gated channel subfamily H member 2
Acc ID: DOID:9003163
Term: Heart Block
Definition: Impaired conduction of cardiac impulse that can occur anywhere along the conduction pathway, such as between the SINOATRIAL NODE and the right atrium (SA block) or between atria and ventricles (AV block). Heart blocks can be classified by the duration, frequency, or completeness of conduction block. Reversibility depends on the degree of structural or functional defects.
Definition Source(s): MESH:D006327
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Kcnh2 ISOKCNH2 (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Conduction disorder of the heartPMID:17088455 PMID:19322600 PMID:19841300 PMID:21410720 PMID:22581653 PMID:22677073 PMID:23465283 PMID:23631430 PMID:23861362 PMID:24033266 PMID:24334129 PMID:25637381 PMID:25741868 PMID:26159999 PMID:28492532
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