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Gene: Ppp2cb (protein phosphatase 2 catalytic subunit beta) Rattus norvegicus
Symbol: Ppp2cb
Name: protein phosphatase 2 catalytic subunit beta
Description: Exhibits protein C-terminus binding activity and protein serine/threonine phosphatase activity. Involved in several processes, including negative regulation of Ras protein signal transduction; positive regulation of microtubule binding activity; and response to lead ion. Predicted to localize to the cytoplasm and protein phosphatase type 2A complex. Orthologous to human PPP2CB (protein phosphatase 2 catalytic subunit beta); PARTICIPATES IN dopamine signaling pathway; phosphatidylinositol 3-kinase-Akt signaling pathway; transforming growth factor-beta Smad dependent signaling pathway; INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; ammonium chloride.
Type: protein-coding
Also known as: MGC94855; PP2A-beta; Pp2a2; Protein phosphatase 2 (formerly 2A) catalytic subunit beta isoform; protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform; protein phosphatase 2, catalytic subunit, beta isoform; protein phosphatase 2, catalytic subunit, beta isozyme; protein phosphatase 2A catalytic alpha subunit; protein phosphatase 2a, catalytic subunit, beta isoform; protein phosphatase-2A-beta; serine/threonine-protein phosphatase 2A catalytic subunit beta isoform
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01662,273,276 - 62,294,767 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1662,273,276 - 62,294,769 (-)Ensembl
Rnor_5.01661,933,984 - 61,955,475 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41662,330,513 - 62,351,968 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11662,330,587 - 62,352,043 (-)NCBI
Celera1656,594,208 - 56,615,135 (-)NCBICelera
Cytogenetic Map16q12.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Ppp2cb
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3381
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.