Sema3e (semaphorin 3E) - Rat Genome Database

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Gene: Sema3e (semaphorin 3E) Rattus norvegicus
Analyze
Symbol: Sema3e
Name: semaphorin 3E
RGD ID: 1310973
Description: Predicted to enable chemorepellent activity; neuropilin binding activity; and semaphorin receptor binding activity. Predicted to be involved in several processes, including angiogenesis; neuron development; and positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction. Predicted to be active in extracellular space and plasma membrane. Biomarker of transient cerebral ischemia. Orthologous to human SEMA3E (semaphorin 3E); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; alpha-Zearalanol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC108350656; LOC296789; sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E; semaphorin-3E; uncharacterized LOC108350656
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8421,252,686 - 21,510,449 (-)NCBIGRCr8
mRatBN7.2420,297,534 - 20,555,287 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl420,299,718 - 20,555,229 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx425,487,004 - 25,736,649 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0421,330,088 - 21,579,569 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0419,713,113 - 19,962,579 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0417,314,745 - 17,594,659 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl417,272,511 - 17,594,598 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0417,560,774 - 17,563,239 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0417,288,508 - 17,411,535 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4416,523,602 - 16,781,878 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1416,525,151 - 16,673,253 (-)NCBI
Celera415,809,991 - 16,063,707 (-)NCBICelera
Cytogenetic Map4q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-butan-2-yl-4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-1,2,4-triazol-3-one  (ISO)
3-Nitrobenzanthrone  (ISO)
4,4'-sulfonyldiphenol  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
atrazine  (EXP)
belinostat  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
Benzo[k]fluoranthene  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
choline  (ISO)
cisplatin  (ISO)
cocaine  (EXP)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
entinostat  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
flutamide  (EXP)
folic acid  (ISO)
genistein  (ISO)
gentamycin  (EXP)
itraconazole  (ISO)
ketoconazole  (ISO)
L-methionine  (ISO)
lead diacetate  (ISO)
lipopolysaccharide  (ISO)
maneb  (ISO)
mercury dibromide  (ISO)
methapyrilene  (ISO)
microcystin-LR  (EXP,ISO)
N-methyl-4-phenylpyridinium  (ISO)
nickel atom  (ISO)
ozone  (ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
perfluorooctanoic acid  (EXP)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
senecionine  (ISO)
silicon dioxide  (EXP)
sodium arsenite  (ISO)
succimer  (ISO)
sunitinib  (ISO)
temozolomide  (ISO)
tetrachloromethane  (ISO)
titanium dioxide  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
trovafloxacin  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. SEMA3E mutation in a patient with CHARGE syndrome. Lalani SR, etal., J Med Genet. 2004 Jul;41(7):e94.
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Sema3E/PlexinD1 signaling inhibits postischemic angiogenesis by regulating endothelial DLL4 and filopodia formation in a rat model of ischemic stroke. Zhou YF, etal., FASEB J. 2019 Apr;33(4):4947-4961. doi: 10.1096/fj.201801706RR. Epub 2019 Jan 17.
Additional References at PubMed
PMID:15550623   PMID:20385769   PMID:22179111   PMID:24006456   PMID:24841563   PMID:30007159  


Genomics

Comparative Map Data
Sema3e
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8421,252,686 - 21,510,449 (-)NCBIGRCr8
mRatBN7.2420,297,534 - 20,555,287 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl420,299,718 - 20,555,229 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx425,487,004 - 25,736,649 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0421,330,088 - 21,579,569 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0419,713,113 - 19,962,579 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0417,314,745 - 17,594,659 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl417,272,511 - 17,594,598 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0417,560,774 - 17,563,239 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0417,288,508 - 17,411,535 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4416,523,602 - 16,781,878 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1416,525,151 - 16,673,253 (-)NCBI
Celera415,809,991 - 16,063,707 (-)NCBICelera
Cytogenetic Map4q12NCBI
SEMA3E
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38783,363,238 - 83,649,139 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl783,363,238 - 83,649,139 (-)EnsemblGRCh38hg38GRCh38
GRCh37782,992,554 - 83,278,455 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36782,831,158 - 83,116,260 (-)NCBINCBI36Build 36hg18NCBI36
Build 34782,637,872 - 82,922,975NCBI
Celera777,694,433 - 77,979,877 (-)NCBICelera
Cytogenetic Map7q21.11NCBI
HuRef777,887,145 - 77,887,879 (-)NCBIHuRef
HuRef777,595,681 - 77,739,611 (-)NCBIHuRef
CHM1_1782,923,279 - 83,208,527 (-)NCBICHM1_1
T2T-CHM13v2.0784,614,452 - 84,899,593 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2782,325,430 - 82,610,645 (-)NCBI
Sema3e
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39514,075,290 - 14,306,703 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl514,075,290 - 14,306,703 (+)EnsemblGRCm39 Ensembl
GRCm38514,025,276 - 14,256,689 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl514,025,276 - 14,256,689 (+)EnsemblGRCm38mm10GRCm38
MGSCv37514,025,276 - 14,256,689 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36514,031,321 - 14,260,320 (+)NCBIMGSCv36mm8
Celera1224,396,140 - 24,628,407 (+)NCBICelera
Cytogenetic Map5A1NCBI
cM Map55.66NCBI
Sema3e
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554102,732,996 - 2,831,210 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554102,732,983 - 2,831,220 (+)NCBIChiLan1.0ChiLan1.0
SEMA3E
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26101,216,178 - 101,499,805 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17149,480,816 - 149,764,448 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0775,329,049 - 75,612,946 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1788,994,889 - 89,274,073 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl788,995,049 - 89,274,241 (-)Ensemblpanpan1.1panPan2
SEMA3E
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11822,881,135 - 22,982,549 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1822,881,133 - 23,116,696 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1822,557,413 - 22,793,028 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01823,332,852 - 23,568,629 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1823,332,879 - 23,569,152 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11822,967,259 - 23,202,826 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01822,502,891 - 22,738,629 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01823,164,304 - 23,400,247 (-)NCBIUU_Cfam_GSD_1.0
Sema3e
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511864,648,977 - 64,883,826 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367341,850,673 - 2,084,891 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367341,850,709 - 2,085,541 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SEMA3E
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl996,682,246 - 96,941,072 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1996,682,178 - 96,941,074 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29106,872,688 - 107,135,027 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SEMA3E
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12165,255,610 - 65,529,021 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2165,415,373 - 65,533,090 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604238,431,351 - 38,737,423 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sema3e
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473931,608,501 - 31,716,640 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473931,606,128 - 31,851,624 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Sema3e
1772 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:463
Count of miRNA genes:242
Interacting mature miRNAs:302
Transcripts:ENSRNOT00000008936
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2302371Stl22Serum triglyceride level QTL 225.15blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521829457114705Rat
2303585Bw86Body weight QTL 864body mass (VT:0001259)body weight (CMO:0000012)41467806559678065Rat
8552903Pigfal2Plasma insulin-like growth factor 1 level QTL 27.3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)4131934116Rat
724557Plsm1Polydactyly-luxate syndrome (PLS) morphotypes QTL 10.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)4127716890Rat
9590100Sffal4Serum free fatty acids level QTL 47.360.05blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)4131934116Rat
8552906Pigfal3Plasma insulin-like growth factor 1 level QTL 3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)41008408955084089Rat
1357341Gluco5Glucose level QTL 56.4adipocyte free fatty acid secretion trait (VT:0010465)absolute change in adipocyte free fatty acid secretion per unit volume (CMO:0001446)4133250345Rat
1357343Gluco4Glucose level QTL 40.00002adipocyte glucose uptake trait (VT:0004185)adipocyte maximal glucose uptake to basal glucose uptake ratio (CMO:0000874)4133250345Rat
6478766Anxrr47Anxiety related response QTL 470.09637locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)41008408955084089Rat
631642Stl2Serum triglyceride level QTL 23.3blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521917856647776Rat
6478769Anxrr48Anxiety related response QTL 480.02514locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)41008408955084089Rat
631261Tcas3Tongue tumor susceptibility QTL 36.88tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)41081417091360527Rat
61333Gluco16Glucose level QTL 164.30.00001adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)4130372989Rat
634323Hc2Hypercalciuria QTL 22.15urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)421079645210796Rat
2313401Anxrr27Anxiety related response QTL 27aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)41793350862933508Rat
61408Scl23Serum cholesterol level QTL 230.0005blood HDL phospholipid amount (VT:0010504)serum high density lipoprotein phospholipid level (CMO:0001567)4127716890Rat
631209Bw2Body weight QTL24.2retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)4994088544463908Rat
8694374Bw155Body weight QTL 1553.390.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)41008408955084089Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45214602146446691Rat
9589046Scfw2Subcutaneous fat weight QTL 25.540.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)4131934116Rat
6478724Anxrr35Anxiety related response QTL 350.00449defecation behavior trait (VT:0010462)defecation measurement (CMO:0000997)41008408955084089Rat
61351Bp33Blood pressure QTL 330.0018arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4127716890Rat
61415Eae11Experimental allergic encephalomyelitis QTL 112.9nervous system integrity trait (VT:0010566)post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)4139505420Rat
1641905Colcr1Colorectal carcinoma resistance QTL 14.30.0003intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)4129494328Rat
619616Bp79Blood pressure QTL 790.0292arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4521460278882945Rat
7387227Uae40Urinary albumin excretion QTL 402.90.0052urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)41794699962946999Rat
1358201Gluco12Glucose level QTL121.6adipocyte glucose uptake trait (VT:0004185)adipocyte maximal glucose uptake (CMO:0000870)4521839229593287Rat
738021Hcar13Hepatocarcinoma resistance QTL 134.3liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)4132584199Rat
1358203Stl19Serum triglyceride level QTL 192.80.002blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521829465958103Rat
9590304Scort17Serum corticosterone level QTL 174.960.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)41008408955084089Rat
9589097Slep11Serum leptin concentration QTL 115.090.001blood leptin amount (VT:0005667)plasma leptin level (CMO:0000781)4131934116Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)411320076180699135Rat
1300141Bp178Blood pressure QTL 178arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)41002490139524530Rat

Markers in Region
D4Got203  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2420,307,643 - 20,307,809 (+)MAPPERmRatBN7.2
Rnor_6.0417,324,850 - 17,325,015NCBIRnor6.0
Rnor_5.0417,296,433 - 17,296,598UniSTSRnor5.0
RGSC_v3.4416,531,527 - 16,531,692UniSTSRGSC3.4
Celera415,817,916 - 15,818,081UniSTS
Cytogenetic Map4q12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 10 48 113 89 88 57 25 57 6 214 95 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000008936   ⟹   ENSRNOP00000008936
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl420,299,718 - 20,555,229 (-)Ensembl
Rnor_6.0 Ensembl417,316,925 - 17,594,598 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000080931   ⟹   ENSRNOP00000072530
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl417,272,511 - 17,440,506 (-)Ensembl
RefSeq Acc Id: NM_001106579   ⟹   NP_001100049
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8421,254,866 - 21,510,374 (-)NCBI
mRatBN7.2420,299,718 - 20,555,229 (-)NCBI
Rnor_6.0417,316,925 - 17,594,598 (-)NCBI
Rnor_5.0417,288,508 - 17,411,535 (-)NCBI
Rnor_5.0417,560,774 - 17,563,239 (-)NCBI
RGSC_v3.4416,523,602 - 16,781,878 (-)RGD
Celera415,809,991 - 16,063,707 (-)RGD
Sequence:
RefSeq Acc Id: XM_017592522   ⟹   XP_017448011
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8421,252,686 - 21,510,426 (-)NCBI
mRatBN7.2420,297,534 - 20,555,285 (-)NCBI
Rnor_6.0417,314,745 - 17,594,659 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039107252   ⟹   XP_038963180
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8421,258,557 - 21,510,449 (-)NCBI
mRatBN7.2420,303,441 - 20,555,287 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001100049 (Get FASTA)   NCBI Sequence Viewer  
  XP_017448011 (Get FASTA)   NCBI Sequence Viewer  
  XP_038963180 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL99467 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000008936
  ENSRNOP00000008936.5
RefSeq Acc Id: NP_001100049   ⟸   NM_001106579
- Peptide Label: precursor
- UniProtKB: D3Z8E2 (UniProtKB/TrEMBL),   A6K5F8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017448011   ⟸   XM_017592522
- Peptide Label: isoform X1
- UniProtKB: D3Z8E2 (UniProtKB/TrEMBL),   A6K5F8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000008936   ⟸   ENSRNOT00000008936
Ensembl Acc Id: ENSRNOP00000072530   ⟸   ENSRNOT00000080931
RefSeq Acc Id: XP_038963180   ⟸   XM_039107252
- Peptide Label: isoform X2
Protein Domains
Ig-like   Sema

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3Z8E2-F1-model_v2 AlphaFold D3Z8E2 1-775 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692823
Promoter ID:EPDNEW_R3348
Type:initiation region
Name:Sema3e_1
Description:semaphorin 3E
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0417,594,545 - 17,594,605EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310973 AgrOrtholog
BioCyc Gene G2FUF-45887 BioCyc
Ensembl Genes ENSRNOG00000006631 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000008936 ENTREZGENE
  ENSRNOT00000008936.6 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL
  2.60.40.10 UniProtKB/TrEMBL
  ligand-binding face of the semaphorins, domain 2 UniProtKB/TrEMBL
InterPro Ig-like UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Immunoglobulin UniProtKB/TrEMBL
  Plexin-like_fold UniProtKB/TrEMBL
  Semap_dom_sf UniProtKB/TrEMBL
  Semaphorin UniProtKB/TrEMBL
  Semaphorin/CD100_Ag UniProtKB/TrEMBL
  Semaphorin_3E UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom UniProtKB/TrEMBL
KEGG Report rno:296789 UniProtKB/TrEMBL
NCBI Gene 296789 ENTREZGENE
PANTHER PTHR11036 UniProtKB/TrEMBL
  PTHR11036:SF22 UniProtKB/TrEMBL
Pfam PF00047 UniProtKB/TrEMBL
  Sema UniProtKB/TrEMBL
PhenoGen Sema3e PhenoGen
PROSITE IG_LIKE UniProtKB/TrEMBL
  SEMA UniProtKB/TrEMBL
RatGTEx ENSRNOG00000006631 RatGTEx
SMART PSI UniProtKB/TrEMBL
  Sema UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP Plexin repeat UniProtKB/TrEMBL
  Sema UniProtKB/TrEMBL
  SSF48726 UniProtKB/TrEMBL
UniProt A6K5F8 ENTREZGENE, UniProtKB/TrEMBL
  D3Z8E2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Sema3e  semaphorin 3E  LOC108350656  uncharacterized LOC108350656  Data merged from RGD:11461120 737654 PROVISIONAL
2016-08-02 LOC108350656  uncharacterized LOC108350656      Symbol and Name status set to provisional 70820 PROVISIONAL
2016-01-21 Sema3e  semaphorin 3E  Sema3e  sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Sema3e  sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E   Sema3e_predicted  sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Sema3e_predicted  sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E (predicted)      Symbol and Name status set to approved 70820 APPROVED