Tp63 (tumor protein p63) - Rat Genome Database

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Gene: Tp63 (tumor protein p63) Rattus norvegicus
Analyze
Symbol: Tp63
Name: tumor protein p63
RGD ID: 620863
Description: Enables DNA-binding transcription factor activity; double-stranded DNA binding activity; and protein domain specific binding activity. Involved in aging; positive regulation of cell population proliferation; and spermatogenesis. Located in dendrite; nucleus; and rough endoplasmic reticulum. Part of protein-containing complex. Human ortholog(s) of this gene implicated in several diseases, including ADULT syndrome; EEC syndrome (multiple); ectodermal dysplasia (multiple); orofacial cleft 8; and split hand-foot malformation 4. Orthologous to human TP63 (tumor protein p63); PARTICIPATES IN altered p53 signaling pathway; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 3,4-dichloroaniline; acrylamide.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: keratinocyte transcription factor KET; Ket; p73L; Tp73l; transformation related protein 63; Trp63; tumor protein 63; tumor protein 63 kDa; tumor protein p73-like
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21174,838,858 - 75,049,764 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1174,838,859 - 75,049,398 (-)Ensembl
Rnor_6.01178,234,853 - 78,456,559 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1178,234,800 - 78,456,501 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01182,262,234 - 82,484,354 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41176,900,622 - 77,200,251 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11176,958,211 - 77,257,840 (-)NCBI
Celera1173,744,494 - 73,953,104 (-)NCBICelera
Cytogenetic Map11q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
adenocarcinoma  (ISO)
ADULT syndrome  (ISO)
amenorrhea  (ISO)
ankyloblepharon-ectodermal defects-cleft lip/palate syndrome  (ISO)
bladder exstrophy  (ISS)
bladder exstrophy-epispadias-cloacal exstrophy complex  (ISO)
breast disease  (ISO)
Breast Neoplasms  (ISO)
carcinoma  (ISO)
cervix uteri carcinoma in situ  (ISO)
cleft lip  (ISO)
cleft palate  (ISO)
Colorectal Neoplasms  (ISO)
Congenital Foot Deformities  (ISO)
Congenital Hand Deformities  (ISO)
Congenital Limb Deformities  (ISO)
Corneal Injuries  (ISO)
Craniofacial Abnormalities  (ISO)
ectodermal dysplasia  (ISO)
ectrodactyly, ectodermal dysplasia, and cleft lip-palate syndrome 3  (ISO)
EEC syndrome  (ISO)
Experimental Diabetes Mellitus  (IEP)
Experimental Neoplasms  (ISO)
Female Urogenital Diseases  (ISO)
gastroesophageal reflux disease  (ISS)
genetic disease  (ISO)
Limb-Mammary Syndrome  (ISO)
lung adenocarcinoma  (ISO)
Lung Neoplasms  (ISO)
Multiple Abnormalities  (ISO)
muscular dystrophy  (ISO)
Neoplasm Metastasis  (ISO)
Neoplastic Cell Transformation  (ISO)
orofacial cleft 8  (ISO)
Ovarian Neoplasms  (ISO)
pancreatic cancer  (ISO)
primary ovarian insufficiency  (ISO)
prostate cancer  (ISO)
prostate carcinoma in situ  (ISO)
Prostatic Neoplasms  (ISO)
Rapp-Hodgkin syndrome  (ISO)
schizophrenia  (ISO)
Skin Abnormalities  (ISO)
split hand-foot malformation  (ISO)
split hand-foot malformation 4  (ISO)
squamous cell carcinoma  (ISO)
squamous cell neoplasm  (ISO)
Sweat Gland Neoplasms  (ISO)
transitional cell carcinoma  (ISO)
urinary bladder cancer  (ISO)
Urologic Neoplasms  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (EXP)
1,2-dibromoethane  (ISO)
1,2-dichloroethane  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-diaminotoluene  (ISO)
2-hydroxypropanoic acid  (ISO)
3,4-dichloroaniline  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxynon-2-enal  (ISO)
4-vinylcyclohexene dioxide  (ISO)
acrylamide  (EXP)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
aflatoxin B2  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
antimonite  (ISO)
antirheumatic drug  (ISO)
apigenin  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butan-1-ol  (ISO)
butane-2,3-dione  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
camptothecin  (ISO)
carbon nanotube  (ISO)
chloropicrin  (ISO)
chrysin  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
cycloheximide  (ISO)
diarsenic trioxide  (ISO)
dibenzo[a,l]pyrene  (ISO)
dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
emodin  (ISO)
entinostat  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
ethylenediaminetetraacetic acid  (ISO)
eugenol  (ISO)
formaldehyde  (ISO)
Fusarenone X  (ISO)
genistein  (EXP,ISO)
glycidol  (ISO)
graphite  (ISO)
hydroxyurea  (ISO)
isobutanol  (ISO)
kaempferol  (ISO)
ketoconazole  (ISO)
lactacystin  (ISO)
lead diacetate  (ISO)
leptomycin B  (ISO)
lithium chloride  (ISO)
luteolin  (ISO)
melphalan  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (EXP)
myricetin  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
nickel dichloride  (ISO)
panobinostat  (ISO)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
phenylmercury acetate  (ISO)
PhIP  (ISO)
progesterone  (ISO)
quercetin  (ISO)
quercitrin  (ISO)
quinolin-8-ol  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sirolimus  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
titanium dioxide  (ISO)
topotecan  (ISO)
trichostatin A  (ISO)
trimellitic anhydride  (ISO)
troglitazone  (ISO)
urethane  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
aging  (IEP)
anatomical structure formation involved in morphogenesis  (ISO)
animal organ morphogenesis  (ISO)
cell aging  (ISO)
cell differentiation  (ISO)
cell population proliferation  (ISO)
cellular response to DNA damage stimulus  (ISO)
chromatin remodeling  (ISO)
cloacal septation  (ISO)
cranial skeletal system development  (ISO)
ectoderm and mesoderm interaction  (ISO)
embryonic forelimb morphogenesis  (ISO)
embryonic hindlimb morphogenesis  (ISO)
embryonic limb morphogenesis  (ISO)
epidermal cell differentiation  (ISO)
epidermal cell division  (ISO)
epidermis development  (ISO)
epithelial cell development  (ISO)
epithelial cell differentiation  (ISO)
establishment of planar polarity  (ISO)
establishment of skin barrier  (ISO,ISS)
female genitalia morphogenesis  (ISO)
hair follicle development  (ISO)
hair follicle morphogenesis  (ISO)
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator  (ISO)
keratinocyte differentiation  (ISO)
keratinocyte proliferation  (ISO)
morphogenesis of a polarized epithelium  (ISO)
multicellular organism aging  (ISO)
negative regulation of apoptotic process  (ISO)
negative regulation of cellular senescence  (ISO)
negative regulation of intracellular estrogen receptor signaling pathway  (ISO)
negative regulation of keratinocyte differentiation  (ISO)
negative regulation of mesoderm development  (ISO)
negative regulation of transcription by RNA polymerase II  (ISO)
negative regulation of transcription, DNA-templated  (ISO)
neuron apoptotic process  (ISO)
Notch signaling pathway  (IEA)
odontogenesis of dentin-containing tooth  (ISO)
pattern specification process  (ISO)
polarized epithelial cell differentiation  (ISO)
positive regulation of apoptotic signaling pathway  (ISO)
positive regulation of cell cycle G1/S phase transition  (ISO)
positive regulation of cell population proliferation  (IMP)
positive regulation of fibroblast apoptotic process  (ISO)
positive regulation of keratinocyte proliferation  (ISO)
positive regulation of mesenchymal cell proliferation  (ISO)
positive regulation of Notch signaling pathway  (ISO)
positive regulation of osteoblast differentiation  (ISO)
positive regulation of somatic stem cell population maintenance  (ISO)
positive regulation of transcription by RNA polymerase II  (ISO)
positive regulation of transcription, DNA-templated  (ISO)
post-anal tail morphogenesis  (ISO)
prostate gland development  (ISO)
prostatic bud formation  (ISO)
protein tetramerization  (IEA)
proximal/distal pattern formation  (ISO)
regulation of cysteine-type endopeptidase activity involved in apoptotic process  (ISO)
regulation of epidermal cell division  (ISO,ISS)
regulation of transcription by RNA polymerase II  (IBA)
skeletal system development  (ISO)
skin epidermis development  (ISO)
skin morphogenesis  (ISO)
smooth muscle tissue development  (ISO)
spermatogenesis  (IEP)
squamous basal epithelial stem cell differentiation involved in prostate gland acinus development  (ISO)
sympathetic nervous system development  (ISO)
urinary bladder development  (ISO)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
1. Alves LU, etal., Genet Mol Biol. 2015 Mar;38(1):37-41. doi: 10.1590/S1415-475738120140125. Epub 2014 Mar 17.
2. Arcolino FO, etal., Int J Exp Pathol. 2010 Apr;91(2):144-54. doi: 10.1111/j.1365-2613.2009.00696.x. Epub 2009 Dec 22.
3. Bamberger C and Schmale H, FEBS Lett 2001 Jul 20;501(2-3):121-6.
4. Barrow LL, etal., J Med Genet. 2002 Aug;39(8):559-66.
5. Celli J, etal., Cell. 1999 Oct 15;99(2):143-53.
6. Clements SE, etal., Br J Dermatol. 2010 Jan;162(1):201-7. doi: 10.1111/j.1365-2133.2009.09496.x. Epub 2009 Nov 9.
7. Djelloul S, etal., Oncogene. 2002 Feb 7;21(7):981-9.
8. Eisenkraft A, etal., Fetal Pediatr Pathol. 2015;34(6):400-6. doi: 10.3109/15513815.2015.1095261. Epub 2015 Oct 16.
9. Farah CA, etal., J Biol Chem. 2005 Mar 11;280(10):9439-49. Epub 2004 Dec 28.
10. Freed-Pastor WA and Prives C, Genes Dev. 2012 Jun 15;26(12):1268-86. doi: 10.1101/gad.190678.112.
11. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
12. Hayashi T, etal., J Androl. 2004 Sep-Oct;25(5):692-8.
13. He Y, etal., J Korean Med Sci. 2008 Oct;23(5):825-32.
14. Hsueh YJ, etal., J Biomed Sci. 2004 Sep-Oct;11(5):641-51.
15. Kruslin B, etal., Pathol Oncol Res. 2006;12(4):205-9. Epub 2006 Dec 25.
16. Lin Z, etal., J Cancer Res Clin Oncol. 2006 Dec;132(12):811-6. Epub 2006 Jun 28.
17. Marchini S, etal., Ann Oncol. 2008 Mar;19(3):501-7. Epub 2007 Nov 12.
18. McGrath JA, etal., Hum Mol Genet. 2001 Feb 1;10(3):221-9.
19. MGD data from the GO Consortium
20. Moore JE, etal., DNA Cell Biol. 2002 May-Jun;21(5-6):443-51.
21. Muller PA and Vousden KH, Nat Cell Biol. 2013 Jan;15(1):2-8. doi: 10.1038/ncb2641.
22. NCBI rat LocusLink and RefSeq merged data July 26, 2002
23. OMIM Disease Annotation Pipeline
24. Ray AK, etal., Clin Genet. 2004 Sep;66(3):217-22.
25. Reiner T, etal., Mol Cancer Res. 2007 Nov;5(11):1171-9. Epub 2007 Nov 2.
26. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
27. RGD automated import pipeline for gene-chemical interactions
28. Schmale H and Bamberger C, Oncogene 1997 Sep;15(11):1363-7.
29. South AP, etal., Br J Dermatol. 2002 Feb;146(2):216-20.
30. Stepan A, etal., Rom J Morphol Embryol. 2009;50(3):461-5.
31. Su P, etal., Int J Colorectal Dis. 2013 Dec;28(12):1621-7. doi: 10.1007/s00384-013-1725-6. Epub 2013 Jun 5.
32. Tuna B, etal., Anal Quant Cytol Histol. 2009 Apr;31(2):118-22.
33. van Bokhoven H, etal., Am J Hum Genet. 2001 Sep;69(3):481-92. Epub 2001 Jul 17.
34. Vernersson Lindahl E, etal., Am J Med Genet A. 2013 Aug;161A(8):1961-71. doi: 10.1002/ajmg.a.36074. Epub 2013 Jun 14.
35. Wei J, etal., PLoS One. 2012;7(5):e35337. doi: 10.1371/journal.pone.0035337. Epub 2012 May 4.
36. Wilkins S, etal., PLoS Genet. 2012;8(12):e1003070. doi: 10.1371/journal.pgen.1003070. Epub 2012 Dec 20.
37. Yin W, etal., J Dent Res. 2010 Aug;89(8):813-7. doi: 10.1177/0022034510366804. Epub 2010 Apr 21.
Additional References at PubMed
PMID:9774969   PMID:10227293   PMID:10227294   PMID:10373484   PMID:10657951   PMID:11106548   PMID:11522642   PMID:11532371   PMID:11641404   PMID:12368184   PMID:12446779   PMID:12446784  
PMID:12789272   PMID:14729569   PMID:15189821   PMID:15361520   PMID:15371309   PMID:15585950   PMID:15982302   PMID:16080917   PMID:16107615   PMID:16337913   PMID:16343436   PMID:16363065  
PMID:16410075   PMID:16466397   PMID:16524929   PMID:16601749   PMID:16618808   PMID:17041603   PMID:17079275   PMID:17093266   PMID:17122775   PMID:17383628   PMID:17522155   PMID:17878916  
PMID:18159078   PMID:18256694   PMID:18326838   PMID:19194497   PMID:19451233   PMID:19815500   PMID:20123734   PMID:21127502   PMID:21285247   PMID:21335238   PMID:21464285   PMID:21930775  
PMID:22274697   PMID:22521434   PMID:22575646   PMID:23608756   PMID:23906066   PMID:24075906   PMID:25417702   PMID:25503409   PMID:25655704   PMID:28827783  


Genomics

Comparative Map Data
Tp63
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21174,838,858 - 75,049,764 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1174,838,859 - 75,049,398 (-)Ensembl
Rnor_6.01178,234,853 - 78,456,559 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1178,234,800 - 78,456,501 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01182,262,234 - 82,484,354 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41176,900,622 - 77,200,251 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11176,958,211 - 77,257,840 (-)NCBI
Celera1173,744,494 - 73,953,104 (-)NCBICelera
Cytogenetic Map11q22NCBI
TP63
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl3189,631,389 - 189,897,276 (+)EnsemblGRCh38hg38GRCh38
GRCh383189,596,746 - 189,897,276 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh373189,314,535 - 189,615,065 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363190,831,910 - 191,097,759 (+)NCBINCBI36hg18NCBI36
Celera3187,783,803 - 188,042,610 (+)NCBI
Cytogenetic Map3q28NCBI
HuRef3186,752,882 - 187,012,887 (+)NCBIHuRef
CHM1_13189,312,090 - 189,577,623 (+)NCBICHM1_1
Trp63
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391625,502,513 - 25,710,838 (+)NCBIGRCm39mm39
GRCm39 Ensembl1625,502,513 - 25,710,852 (+)Ensembl
GRCm381625,683,763 - 25,892,088 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1625,683,763 - 25,892,102 (+)EnsemblGRCm38mm10GRCm38
MGSCv371625,683,851 - 25,892,174 (+)NCBIGRCm37mm9NCBIm37
MGSCv361625,717,291 - 25,807,429 (+)NCBImm8
Celera1626,227,614 - 26,435,704 (+)NCBICelera
Cytogenetic Map16B1NCBI
cM Map1617.37NCBI
Tp63
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542018,176,155 - 18,384,786 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542018,178,639 - 18,384,786 (-)NCBIChiLan1.0ChiLan1.0
TP63
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.13195,172,810 - 195,473,085 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3195,199,167 - 195,474,104 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v03186,651,879 - 186,918,300 (+)NCBIMhudiblu_PPA_v0panPan3
TP63
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13421,766,861 - 21,985,095 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3421,766,496 - 21,983,046 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3425,860,495 - 26,078,655 (+)NCBI
ROS_Cfam_1.03421,700,749 - 21,919,495 (+)NCBI
UMICH_Zoey_3.13421,716,204 - 21,934,749 (+)NCBI
UNSW_CanFamBas_1.03421,710,660 - 21,927,985 (+)NCBI
UU_Cfam_GSD_1.03421,951,749 - 22,170,136 (+)NCBI
Tp63
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602114,397,903 - 114,613,831 (-)NCBI
SpeTri2.0NW_004936578492,267 - 705,282 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TP63
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13127,116,104 - 127,347,075 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113127,115,990 - 127,347,082 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213136,309,804 - 136,515,766 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TP63
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11583,861,489 - 84,126,675 (+)NCBI
Vero_WHO_p1.0NW_02366604157,444,595 - 57,708,553 (+)NCBI
Tp63
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473067,283,444 - 67,489,808 (-)NCBI


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)111897620886241447Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112767241082846715Rat
1300110Stl7Serum triglyceride level QTL 74.64blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)112952841882566702Rat
2298551Neuinf10Neuroinflammation QTL 103.7nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)113123913478851519Rat
70180BpQTLcluster10Blood pressure QTL cluster 103.19arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)113491804179918041Rat
1300135Rf19Renal function QTL 193.38blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)114094618882566702Rat
2312566Glom20Glomerulus QTL 203.60.001kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)114428575982566702Rat
1581565Pur10Proteinuria QTL 100.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)114480331882846466Rat
1581572Uae35Urinary albumin excretion QTL 350.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)114480331882846466Rat
4889859Pur28Proteinuria QTL 2819.50.001total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)114545932375190161Rat
724561Plsm4Polydactyly-luxate syndrome (PLS) morphotypes QTL 40.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)115445753486241447Rat
4889521Gluco62Glucose level QTL 622.820.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)115513672982993457Rat
7411658Foco27Food consumption QTL 2716.20.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)115635142486241447Rat
631506Bp104Blood pressure QTL 1042.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)115980279482566545Rat
70208Niddm22Non-insulin dependent diabetes mellitus QTL 223.61blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)115980279482566553Rat
10058954Gmadr7Adrenal mass QTL 72.490.0049adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)116034659086241447Rat
1549848Bvd6Brain ventricular dilatation QTL 63.10.0001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)116611332182169223Rat
634339Niddm50Non-insulin dependent diabetes mellitus QTL 503.32blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)116642214886241447Rat
1354593Stl12Serum triglyceride level QTL 123.36blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)116642214886241447Rat
1354656Bvd3Brain ventricular dilatation QTL 33.640.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)116944607082846715Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2362
Count of miRNA genes:338
Interacting mature miRNAs:471
Transcripts:ENSRNOT00000002636, ENSRNOT00000036179, ENSRNOT00000036193, ENSRNOT00000067251, ENSRNOT00000068116
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 1
Low 2 9 13 8 11 8 12 22 9 8
Below cutoff 2 14 21 14 6 14 43 21 15 2

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001127339 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001127341 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001127342 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001127343 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001127344 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_019221 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006248500 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008768791 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597881 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AJ277446 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ277447 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ277448 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ277449 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ277450 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ277451 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ277452 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ277453 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473999 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000222 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y10258 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000002636   ⟹   ENSRNOP00000002636
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1174,838,859 - 74,931,425 (-)Ensembl
Rnor_6.0 Ensembl1178,234,854 - 78,327,282 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000036179   ⟹   ENSRNOP00000032308
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1174,854,156 - 75,049,398 (-)Ensembl
Rnor_6.0 Ensembl1178,250,397 - 78,456,200 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000036193   ⟹   ENSRNOP00000033463
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1178,234,800 - 78,456,501 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000067251   ⟹   ENSRNOP00000059178
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1174,838,859 - 75,049,398 (-)Ensembl
Rnor_6.0 Ensembl1178,234,854 - 78,456,200 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000068116   ⟹   ENSRNOP00000061884
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1174,838,859 - 75,049,398 (-)Ensembl
Rnor_6.0 Ensembl1178,234,854 - 78,341,349 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000113030   ⟹   ENSRNOP00000089600
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1174,912,864 - 75,049,398 (-)Ensembl
RefSeq Acc Id: NM_001127339   ⟹   NP_001120811
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21174,838,858 - 75,049,398 (-)NCBI
Rnor_6.01178,234,853 - 78,456,200 (-)NCBI
Rnor_5.01182,262,234 - 82,484,354 (+)NCBI
RGSC_v3.41176,900,622 - 77,200,251 (-)RGD
Celera1173,744,494 - 73,953,104 (-)RGD
Sequence:
RefSeq Acc Id: NM_001127341   ⟹   NP_001120813
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21174,854,400 - 75,049,398 (-)NCBI
Rnor_6.01178,250,397 - 78,456,200 (-)NCBI
Rnor_5.01182,262,234 - 82,484,354 (+)NCBI
RGSC_v3.41176,900,622 - 77,200,251 (-)RGD
Celera1173,760,076 - 73,953,104 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001127342   ⟹   NP_001120814
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21174,838,858 - 74,931,291 (-)NCBI
Rnor_6.01178,234,853 - 78,327,282 (-)NCBI
Rnor_5.01182,262,234 - 82,484,354 (+)NCBI
RGSC_v3.41176,900,622 - 77,200,251 (-)RGD
Celera1173,744,494 - 73,836,976 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001127343   ⟹   NP_001120815
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21174,838,858 - 74,931,291 (-)NCBI
Rnor_6.01178,234,853 - 78,327,282 (-)NCBI
Rnor_5.01182,262,234 - 82,484,354 (+)NCBI
RGSC_v3.41176,900,622 - 77,200,251 (-)RGD
Celera1173,744,494 - 73,836,976 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001127344   ⟹   NP_001120816
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21174,854,400 - 74,931,291 (-)NCBI
Rnor_6.01178,250,397 - 78,327,282 (-)NCBI
Rnor_5.01182,262,234 - 82,484,354 (+)NCBI
RGSC_v3.41176,900,622 - 77,200,251 (-)RGD
Celera1173,760,076 - 73,836,976 (-)NCBI
Sequence:
RefSeq Acc Id: NM_019221   ⟹   NP_062094
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21174,838,858 - 75,049,398 (-)NCBI
Rnor_6.01178,234,853 - 78,456,200 (-)NCBI
Rnor_5.01182,262,234 - 82,484,354 (+)NCBI
RGSC_v3.41176,900,622 - 77,200,251 (-)RGD
Celera1173,744,494 - 73,953,104 (-)RGD
Sequence:
RefSeq Acc Id: XM_006248500   ⟹   XP_006248562
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21174,852,197 - 75,049,764 (-)NCBI
Rnor_6.01178,245,462 - 78,456,281 (-)NCBI
Rnor_5.01182,262,234 - 82,484,354 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017597881   ⟹   XP_017453370
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21174,838,876 - 75,049,764 (-)NCBI
Rnor_6.01178,234,871 - 78,456,281 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_062094   ⟸   NM_019221
- Peptide Label: isoform a
- UniProtKB: Q9JJP6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001120811   ⟸   NM_001127339
- Peptide Label: isoform b
- UniProtKB: Q9JJP6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001120814   ⟸   NM_001127342
- Peptide Label: isoform d
- UniProtKB: Q9JJP6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001120815   ⟸   NM_001127343
- Peptide Label: isoform e
- UniProtKB: Q9JJP6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001120813   ⟸   NM_001127341
- Peptide Label: isoform c
- UniProtKB: Q9JJP6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001120816   ⟸   NM_001127344
- Peptide Label: isoform f
- UniProtKB: Q9JJP6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006248562   ⟸   XM_006248500
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017453370   ⟸   XM_017597881
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000059178   ⟸   ENSRNOT00000067251
RefSeq Acc Id: ENSRNOP00000033463   ⟸   ENSRNOT00000036193
RefSeq Acc Id: ENSRNOP00000032308   ⟸   ENSRNOT00000036179
RefSeq Acc Id: ENSRNOP00000002636   ⟸   ENSRNOT00000002636
RefSeq Acc Id: ENSRNOP00000061884   ⟸   ENSRNOT00000068116
RefSeq Acc Id: ENSRNOP00000089600   ⟸   ENSRNOT00000113030
Protein Domains
SAM

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BUF/N (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
DA/OlaHsd (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
F344/Stm (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FXLE16/Stm (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/FarMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrcAek (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrcAek (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrcAek (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
M520/NRrrcMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MWF/Hsd (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/OlalpcvMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/RijCrl (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620863 AgrOrtholog
Ensembl Genes ENSRNOG00000001924 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSRNOP00000002636 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000032308 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000033463 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000059178 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000061884 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000002636 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000036179 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000036193 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000067251 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000068116 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.150.50 UniProtKB/Swiss-Prot
  2.60.40.720 UniProtKB/Swiss-Prot
  4.10.170.10 UniProtKB/Swiss-Prot
InterPro p53-like_TF_DNA-bd UniProtKB/Swiss-Prot
  p53/RUNT-type_TF_DNA-bd_sf UniProtKB/Swiss-Prot
  p53_DNA-bd UniProtKB/Swiss-Prot
  p53_tetramer_sf UniProtKB/Swiss-Prot
  p53_tetrameristn UniProtKB/Swiss-Prot
  p53_tumour_suppressor UniProtKB/Swiss-Prot
  SAM UniProtKB/Swiss-Prot
  SAM/pointed_sf UniProtKB/Swiss-Prot
  Tp63 UniProtKB/Swiss-Prot
  Tumor-p63_SAM UniProtKB/Swiss-Prot
KEGG Report rno:246334 UniProtKB/Swiss-Prot
NCBI Gene 246334 ENTREZGENE
PANTHER PTHR11447 UniProtKB/Swiss-Prot
  PTHR11447:SF8 UniProtKB/Swiss-Prot
Pfam P53 UniProtKB/Swiss-Prot
  P53_tetramer UniProtKB/Swiss-Prot
  SAM_2 UniProtKB/Swiss-Prot
PhenoGen Tp63 PhenoGen
PRINTS P53SUPPRESSR UniProtKB/Swiss-Prot
PROSITE P53 UniProtKB/Swiss-Prot
SMART SAM UniProtKB/Swiss-Prot
Superfamily-SCOP SSF47719 UniProtKB/Swiss-Prot
  SSF47769 UniProtKB/Swiss-Prot
  SSF49417 UniProtKB/Swiss-Prot
UniProt P63_RAT UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary Q99JD6 UniProtKB/Swiss-Prot
  Q99JD7 UniProtKB/Swiss-Prot
  Q99JD8 UniProtKB/Swiss-Prot
  Q99JD9 UniProtKB/Swiss-Prot
  Q99JE0 UniProtKB/Swiss-Prot
  Q99JE1 UniProtKB/Swiss-Prot
  Q99JE2 UniProtKB/Swiss-Prot
  Q99JE3 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2009-12-21 Tp63  tumor protein p63  Tp73l  tumor protein p73-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-10-23 Tp73l  tumor protein p73-like  Trp63  transformation related protein 63  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2003-04-09 Trp63  transformation related protein 63      Symbol and Name updated 629477 APPROVED
2003-03-12 Trp63  transformation related protein 63  Tp63  tumor protein 63 kDa   Data Merged 628472 PROVISIONAL
2002-08-07 Trp63  transformation related protein 63      Symbol and Name status set to provisional 70820 PROVISIONAL
2002-06-10 Tp63  tumor protein 63 kDa       Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_transcript transcript consists of multiple KET isoforms that are colocalized in different rat tissues 634449