Kpna3 (karyopherin subunit alpha 3) - Rat Genome Database

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Gene: Kpna3 (karyopherin subunit alpha 3) Rattus norvegicus
Analyze
Symbol: Kpna3
Name: karyopherin subunit alpha 3
RGD ID: 1311339
Description: Predicted to enable nuclear import signal receptor activity and nuclear localization sequence binding activity. Predicted to be involved in NLS-bearing protein import into nucleus. Predicted to be located in cytoplasm. Predicted to be part of NLS-dependent protein nuclear import complex. Predicted to be active in nucleoplasm. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 88. Orthologous to human KPNA3 (karyopherin subunit alpha 3); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: importin; importin subunit alpha-3; importin subunit alpha-4; karyopherin (importin) alpha 3; karyopherin alpha 3; LOC361055; predicted role in nuclear import
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81539,712,375 - 39,786,127 (-)NCBIGRCr8
mRatBN7.21535,536,310 - 35,610,066 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1535,536,316 - 35,610,419 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1537,402,845 - 37,475,011 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01538,553,491 - 38,625,651 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01536,998,924 - 37,070,757 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01541,696,356 - 41,770,112 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1541,698,281 - 41,770,112 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01545,500,469 - 45,574,246 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41540,513,214 - 40,585,152 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11540,528,913 - 40,600,852 (-)NCBI
Celera1535,235,629 - 35,307,265 (-)NCBICelera
Cytogenetic Map15p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2,6-dinitrotoluene  (EXP)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
5-fluorouracil  (ISO)
acetylsalicylic acid  (ISO)
acrylamide  (EXP)
actinomycin D  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
aristolochic acid A  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP,ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
coumestrol  (ISO)
cyproterone acetate  (EXP)
decabromodiphenyl ether  (ISO)
dexamethasone  (EXP)
Dibutyl phosphate  (ISO)
dioxygen  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
ethyl methanesulfonate  (ISO)
finasteride  (EXP)
flutamide  (EXP)
formaldehyde  (ISO)
FR900359  (ISO)
isoprenaline  (EXP)
ivermectin  (ISO)
ketoconazole  (ISO)
lipopolysaccharide  (ISO)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
phenol red  (ISO)
pirinixic acid  (EXP)
poly(I:C)  (EXP)
potassium dichromate  (ISO)
quercetin  (ISO)
rimonabant  (ISO)
sodium arsenite  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
trimellitic anhydride  (ISO)
triphenyl phosphate  (ISO)
tunicamycin  (ISO)
uranium atom  (ISO)
vitamin E  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11744694   PMID:12477932   PMID:16906019   PMID:25931508   PMID:26875149   PMID:31505169   PMID:32814091  


Genomics

Comparative Map Data
Kpna3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81539,712,375 - 39,786,127 (-)NCBIGRCr8
mRatBN7.21535,536,310 - 35,610,066 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1535,536,316 - 35,610,419 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1537,402,845 - 37,475,011 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01538,553,491 - 38,625,651 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01536,998,924 - 37,070,757 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01541,696,356 - 41,770,112 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1541,698,281 - 41,770,112 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01545,500,469 - 45,574,246 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41540,513,214 - 40,585,152 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11540,528,913 - 40,600,852 (-)NCBI
Celera1535,235,629 - 35,307,265 (-)NCBICelera
Cytogenetic Map15p12NCBI
KPNA3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381349,699,320 - 49,792,682 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1349,699,320 - 49,792,682 (-)EnsemblGRCh38hg38GRCh38
GRCh371350,273,456 - 50,366,818 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361349,171,462 - 49,265,058 (-)NCBINCBI36Build 36hg18NCBI36
Build 341349,171,462 - 49,265,058NCBI
Celera1331,328,396 - 31,421,989 (-)NCBICelera
Cytogenetic Map13q14.2NCBI
HuRef1331,066,776 - 31,160,103 (-)NCBIHuRef
CHM1_11350,240,998 - 50,334,562 (-)NCBICHM1_1
T2T-CHM13v2.01348,918,230 - 49,011,561 (-)NCBIT2T-CHM13v2.0
Kpna3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391461,602,635 - 61,677,396 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1461,602,660 - 61,677,323 (-)EnsemblGRCm39 Ensembl
GRCm381461,365,186 - 61,439,947 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1461,365,211 - 61,439,874 (-)EnsemblGRCm38mm10GRCm38
MGSCv371461,984,023 - 62,058,784 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361460,319,296 - 60,393,984 (-)NCBIMGSCv36mm8
Celera1459,132,256 - 59,207,222 (-)NCBICelera
Cytogenetic Map14D1NCBI
cM Map1432.76NCBI
Kpna3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554313,147,679 - 3,212,306 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554313,147,679 - 3,176,577 (-)NCBIChiLan1.0ChiLan1.0
KPNA3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21451,137,959 - 51,234,859 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11349,789,631 - 49,886,323 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01330,838,320 - 30,931,608 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11349,586,544 - 49,679,899 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1349,586,544 - 49,679,906 (-)Ensemblpanpan1.1panPan2
KPNA3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1222,064,733 - 2,110,524 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl222,064,731 - 2,108,414 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha222,047,113 - 2,139,532 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0222,007,822 - 2,100,805 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl222,007,822 - 2,100,799 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1221,917,661 - 2,010,070 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0221,966,867 - 2,059,505 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0221,985,280 - 2,077,707 (+)NCBIUU_Cfam_GSD_1.0
Kpna3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945159,253,953 - 159,299,123 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365652,737,218 - 2,775,798 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365652,738,003 - 2,775,814 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KPNA3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1117,948,210 - 18,031,946 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11117,948,210 - 18,033,818 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21118,085,064 - 18,165,110 (-)NCBISscrofa10.2Sscrofa10.2susScr3
KPNA3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1327,615,040 - 27,711,287 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl327,614,983 - 27,711,358 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605716,171,549 - 16,268,410 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kpna3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247484,902,484 - 4,961,186 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247484,902,570 - 4,961,191 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Kpna3
347 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:65
Count of miRNA genes:53
Interacting mature miRNAs:61
Transcripts:ENSRNOT00000034400
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331729Rf42Renal function QTL 423.071kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)151736289773690657Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15142356671Rat
10755503Bp391Blood pressure QTL 3912.37arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)152024860037896129Rat
1582227Gluco30Glucose level QTL 303.60.0003blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)152803066582262678Rat
1582228Epfw3Epididymal fat weight QTL 34.10.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)152803066582262678Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)152280624098288169Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)152280624098288169Rat
10401805Kidm51Kidney mass QTL 51kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1530632945306329Rat
2293686Bmd36Bone mineral density QTL 367.40.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)153361105871477291Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151249614165205939Rat
2298549Neuinf12Neuroinflammation QTL 123.5nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)15155302115Rat
2293691Bmd37Bone mineral density QTL 376.60.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)153361105871477291Rat
2293688Bss29Bone structure and strength QTL 295.310.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)151111114256111142Rat
1582214Stl21Serum triglyceride level QTL 213.10.022blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)152803066582262678Rat
631273Lecl2Lens clarity QTL 20.001lens clarity trait (VT:0001304)age of onset/diagnosis of cataract (CMO:0001584)151059608955596089Rat
2300167Bmd63Bone mineral density QTL 635.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)151111114256111142Rat
731170Pur3Proteinuria QTL 32.30.0005urine protein amount (VT:0005160)urine protein excretion rate (CMO:0000759)15141686771Rat
738017Hcas7Hepatocarcinoma susceptibility QTL 72.91liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)15226636846921453Rat
152025253Hrtrt24Heart rate QTL 243.82heart pumping trait (VT:2000009)152788577486257085Rat
10054130Srcrt8Stress Responsive Cort QTL 82.180.0085blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)152211793367117933Rat
2300173Bmd62Bone mineral density QTL 6212.80.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)151111114256111142Rat
2324620Coatc3Coat color QTL 3coat/hair pigmentation trait (VT:0010463)pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)151985656646187442Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151672552880672115Rat
1582251Gluco24Glucose level QTL 243.20.0008blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)15553075650530756Rat
1598828Glom14Glomerulus QTL 142.5kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)153405413979054139Rat
1582242Gluco28Glucose level QTL 283.30.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)152803066582262678Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)152280624098288169Rat
1582244Bw79Body weight QTL 7940.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)152803066582262678Rat

Markers in Region
RH143738  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81539,780,840 - 39,780,983 (+)Marker Load Pipeline
mRatBN7.21535,604,779 - 35,604,922 (+)MAPPERmRatBN7.2
Rnor_6.01541,764,826 - 41,764,968NCBIRnor6.0
Rnor_5.01545,568,959 - 45,569,101UniSTSRnor5.0
RGSC_v3.41540,579,866 - 40,580,008UniSTSRGSC3.4
Celera1535,301,989 - 35,302,131UniSTS
RH 3.4 Map15226.2UniSTS
Cytogenetic Map15p12UniSTS
RH143369  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21535,605,361 - 35,605,493 (+)MAPPERmRatBN7.2
Rnor_6.01541,765,408 - 41,765,539NCBIRnor6.0
Rnor_5.01545,569,541 - 45,569,672UniSTSRnor5.0
RGSC_v3.41540,580,448 - 40,580,579UniSTSRGSC3.4
Celera1535,302,571 - 35,302,702UniSTS
RH 3.4 Map15222.5UniSTS
Cytogenetic Map15p12UniSTS
D13S663E  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21535,538,228 - 35,538,326 (+)MAPPERmRatBN7.2
Rnor_6.01541,698,275 - 41,698,372NCBIRnor6.0
Rnor_5.01545,502,388 - 45,502,485UniSTSRnor5.0
RGSC_v3.41540,513,208 - 40,513,305UniSTSRGSC3.4
Celera1535,235,623 - 35,235,720UniSTS
Cytogenetic Map15p12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000034400   ⟹   ENSRNOP00000032371
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1535,536,316 - 35,610,076 (-)Ensembl
Rnor_6.0 Ensembl1541,698,281 - 41,770,112 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000101221   ⟹   ENSRNOP00000083022
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1535,536,316 - 35,560,883 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000106096   ⟹   ENSRNOP00000084014
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1535,536,316 - 35,610,419 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000111588   ⟹   ENSRNOP00000093015
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1535,536,316 - 35,610,059 (-)Ensembl
RefSeq Acc Id: NM_001014792   ⟹   NP_001014792
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81539,714,300 - 39,786,127 (-)NCBI
mRatBN7.21535,538,235 - 35,610,066 (-)NCBI
Rnor_6.01541,698,281 - 41,770,112 (-)NCBI
Rnor_5.01545,500,469 - 45,574,246 (-)NCBI
RGSC_v3.41540,513,214 - 40,585,152 (-)RGD
Celera1535,235,629 - 35,307,265 (-)RGD
Sequence:
RefSeq Acc Id: XM_006252127   ⟹   XP_006252189
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81539,712,375 - 39,785,588 (-)NCBI
mRatBN7.21535,536,310 - 35,609,527 (-)NCBI
Rnor_6.01541,696,356 - 41,769,605 (-)NCBI
Rnor_5.01545,500,469 - 45,574,246 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039093503   ⟹   XP_038949431
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81539,712,375 - 39,768,982 (-)NCBI
mRatBN7.21535,536,310 - 35,592,921 (-)NCBI
RefSeq Acc Id: XM_039093504   ⟹   XP_038949432
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81539,712,375 - 39,786,044 (-)NCBI
mRatBN7.21535,536,310 - 35,609,983 (-)NCBI
RefSeq Acc Id: XM_063274414   ⟹   XP_063130484
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81539,712,375 - 39,780,543 (-)NCBI
RefSeq Acc Id: NP_001014792   ⟸   NM_001014792
- UniProtKB: Q56R18 (UniProtKB/TrEMBL),   D3ZU98 (UniProtKB/TrEMBL),   A0A8I5ZWC6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006252189   ⟸   XM_006252127
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZWC6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000032371   ⟸   ENSRNOT00000034400
RefSeq Acc Id: XP_038949432   ⟸   XM_039093504
- Peptide Label: isoform X2
- UniProtKB: A6K6B9 (UniProtKB/TrEMBL),   A0A8I5ZWC6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038949431   ⟸   XM_039093503
- Peptide Label: isoform X2
- UniProtKB: A6K6B9 (UniProtKB/TrEMBL),   A0A8I5ZWC6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000093015   ⟸   ENSRNOT00000111588
Ensembl Acc Id: ENSRNOP00000084014   ⟸   ENSRNOT00000106096
Ensembl Acc Id: ENSRNOP00000083022   ⟸   ENSRNOT00000101221
RefSeq Acc Id: XP_063130484   ⟸   XM_063274414
- Peptide Label: isoform X2
- UniProtKB: A6K6B9 (UniProtKB/TrEMBL),   A0A8I5ZWC6 (UniProtKB/TrEMBL)
Protein Domains
IBB

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q56R18-F1-model_v2 AlphaFold Q56R18 1-521 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699743
Promoter ID:EPDNEW_R10267
Type:initiation region
Name:Kpna3_1
Description:karyopherin subunit alpha 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01541,770,168 - 41,770,228EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311339 AgrOrtholog
BioCyc Gene G2FUF-13504 BioCyc
Ensembl Genes ENSRNOG00000014945 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000034400.4 UniProtKB/TrEMBL
  ENSRNOT00000101221.1 UniProtKB/TrEMBL
  ENSRNOT00000106096.1 UniProtKB/TrEMBL
  ENSRNOT00000111588.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.690 UniProtKB/TrEMBL
  1.25.10.10 UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  Arm_3 UniProtKB/TrEMBL
  Armadillo UniProtKB/TrEMBL
  Importin-a-like_IBB-bd_dom UniProtKB/TrEMBL
  Importin-a_IBB_sf UniProtKB/TrEMBL
  Importing_su_alpha UniProtKB/TrEMBL
KEGG Report rno:361055 UniProtKB/TrEMBL
NCBI Gene 361055 ENTREZGENE
PANTHER IMPORTIN ALPHA UniProtKB/TrEMBL
  IMPORTIN SUBUNIT ALPHA-4 UniProtKB/TrEMBL
Pfam Arm UniProtKB/TrEMBL
  Arm_3 UniProtKB/TrEMBL
  IBB UniProtKB/TrEMBL
PhenoGen Kpna3 PhenoGen
PIRSF Importin_alpha UniProtKB/TrEMBL
PROSITE ARM_REPEAT UniProtKB/TrEMBL
  IBB UniProtKB/TrEMBL
RatGTEx ENSRNOG00000014945 RatGTEx
SMART ARM UniProtKB/TrEMBL
Superfamily-SCOP ARM-type_fold UniProtKB/TrEMBL
UniProt A0A8I5ZWC6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZYF9_RAT UniProtKB/TrEMBL
  A0A8I6AIU8_RAT UniProtKB/TrEMBL
  A6K6B9 ENTREZGENE, UniProtKB/TrEMBL
  D3ZU98 ENTREZGENE
  Q56R18 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary D3ZU98 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-11 Kpna3  karyopherin subunit alpha 3  Kpna3  karyopherin alpha 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2009-12-15 Kpna3  karyopherin alpha 3  Kpna3  karyopherin (importin) alpha 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Kpna3  karyopherin (importin) alpha 3  Kpna3_predicted  karyopherin (importin) alpha 3 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Kpna3_predicted  karyopherin (importin) alpha 3 (predicted)      Symbol and Name status set to approved 70820 APPROVED