Gene: Mthfd1l (methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like) Rattus norvegicus
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Symbol: Mthfd1l
Name: methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
Description: ENCODES a protein that exhibits ATP binding (ortholog); formate-tetrahydrofolate ligase activity (ortholog); protein homodimerization activity (ortholog); INVOLVED IN 10-formyltetrahydrofolate biosynthetic process (ortholog); embryonic neurocranium morphogenesis (ortholog); embryonic viscerocranium morphogenesis (ortholog); PARTICIPATES IN folate cycle metabolic pathway; folate metabolic pathway; hereditary folate malabsorption pathway; ASSOCIATED WITH Craniofacial Abnormalities (ortholog); neural tube defect (ortholog); FOUND IN mitochondrion (ortholog); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; aflatoxin B1; all-trans-retinoic acid
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: formyltetrahydrofolate synthetase domain containing 1; Fthfsdc1; LOC361472; monofunctional C1-tetrahydrofolate synthase, mitochondrial
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0140,529,092 - 40,719,232 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0141,876,363 - 42,065,394 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4134,759,445 - 34,800,865 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1134,690,706 - 34,876,868 (+)NCBI
Celera136,135,294 - 36,323,637 (+)NCBICelera
Cytogenetic Map1p11-q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Mthfd1l
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1307311
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-01-30
Status: ACTIVE