Calb2 (calbindin 2) - Rat Genome Database

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Gene: Calb2 (calbindin 2) Rattus norvegicus
Analyze
Symbol: Calb2
Name: calbindin 2
RGD ID: 620981
Description: Enables calcium ion binding activity. Predicted to be involved in regulation of long-term synaptic potentiation and regulation of presynaptic cytosolic calcium ion concentration. Located in cuticular plate and stereocilium. Is active in synapse. Orthologous to human CALB2 (calbindin 2); PARTICIPATES IN calcium/calcium-mediated signaling pathway; INTERACTS WITH (R)-lipoic acid; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: calretinin; CR; MGC105356
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Candidate Gene For: Eau8
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81955,023,849 - 55,050,858 (-)NCBIGRCr8
mRatBN7.21938,114,435 - 38,141,438 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1938,114,424 - 38,141,438 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1944,920,886 - 44,947,919 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01945,574,230 - 45,601,269 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01947,883,801 - 47,910,840 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01941,482,743 - 41,509,617 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1941,482,728 - 41,509,658 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01952,310,641 - 52,337,700 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41940,023,072 - 40,051,150 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11940,027,952 - 40,056,031 (-)NCBI
Celera1937,512,226 - 37,538,062 (-)NCBICelera
Cytogenetic Map19q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(R)-lipoic acid  (EXP)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2-hydroxypropanoic acid  (ISO)
2-palmitoylglycerol  (ISO)
3-chloropropane-1,2-diol  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methylcholanthrene  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
amphetamine  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
asbestos  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
Brodifacoum  (EXP)
butanal  (ISO)
Butylparaben  (ISO)
C60 fullerene  (EXP)
cadmium atom  (ISO)
carmustine  (ISO)
cefaloridine  (EXP)
CGP 52608  (ISO)
chlordecone  (ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
cytarabine  (ISO)
DDE  (EXP)
DDT  (EXP)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
diethylstilbestrol  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
ethanol  (EXP,ISO)
ethylparaben  (ISO)
flusilazole  (EXP)
flutamide  (EXP)
hydroquinone  (ISO)
indometacin  (ISO)
ketamine  (EXP)
ketoconazole  (EXP)
L-ascorbic acid  (EXP)
lead diacetate  (EXP)
lead(0)  (EXP,ISO)
Licochalcone B  (ISO)
lipoic acid  (EXP)
maneb  (ISO)
methamphetamine  (EXP)
methimazole  (EXP)
methylisothiazolinone  (ISO)
methylmercury chloride  (ISO)
methylparaben  (ISO)
N-Nitrosopyrrolidine  (ISO)
nickel atom  (ISO)
O-methyleugenol  (ISO)
oxaliplatin  (ISO)
ozone  (ISO)
panobinostat  (ISO)
paraquat  (ISO)
PCB138  (EXP,ISO)
pentanal  (ISO)
picrotoxin  (EXP)
pirinixic acid  (EXP,ISO)
potassium dichromate  (ISO)
rac-lactic acid  (ISO)
raloxifene  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
simvastatin  (EXP)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sotorasib  (ISO)
sterigmatocystin  (EXP)
temozolomide  (ISO)
toluene  (EXP)
trametinib  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. De novo expression of calretinin in trimethyltin-induced degeneration of developing rat hippocampus. Businaro R, etal., Brain Res Mol Brain Res 2002 Jan 31;98(1-2):141-4.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. The concentrations of calcium buffering proteins in mammalian cochlear hair cells. Hackney CM, etal., J Neurosci. 2005 Aug 24;25(34):7867-75.
4. Calretinin and CD34 immunoreactivity of the endometrial stroma in normal endometrium and change of the immunoreactivity in dysfunctional uterine bleeding with evidence of 'disordered endometrial stroma'. Mai KT, etal., Pathology. 2008 Aug;40(5):493-9.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. Structural and biochemical characterization of neuronal calretinin domain I-II (residues 1-100). Comparison to homologous calbindin D28k domain I-II (residues 1-93). Palczewska M, etal., Eur J Biochem. 2001 Dec;268(23):6229-37.
8. GOA pipeline RGD automated data pipeline
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Comprehensive gene review and curation RGD comprehensive gene curation
11. Cytosolic Ca2+ buffers. Schwaller B, Cold Spring Harb Perspect Biol. 2010 Nov;2(11):a004051. doi: 10.1101/cshperspect.a004051. Epub 2010 Oct 13.
12. Nucleotide sequence of rat calretinin cDNA. Strauss KI and Jacobowitz DM, Neurochem Int 1993 Jun;22(6):541-6.
13. Immunocytochemical detection of calretinin in the claustrum and endopiriform nucleus of the chinchilla. Szalak R, etal., Pol J Vet Sci. 2015;18(4):857-63. doi: 10.1515/pjvs-2015-0111.
14. Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins. Wilhelm BG, etal., Science. 2014 May 30;344(6187):1023-8. doi: 10.1126/science.1252884.
15. Distribution of calretinin, calbindin D28k, and parvalbumin in subcellular fractions of rat cerebellum: effects of calcium. Winsky L and Kuznicki J, J Neurochem. 1995 Jul;65(1):381-8.
Additional References at PubMed
PMID:1988053   PMID:7918640   PMID:12477932   PMID:12577320   PMID:12868005   PMID:14730585   PMID:15093134   PMID:15355314   PMID:15489334   PMID:17177263   PMID:17965879   PMID:18720478  
PMID:18769561   PMID:21080000   PMID:21394464   PMID:21835217   PMID:22037839   PMID:22221733   PMID:23273895   PMID:24134921   PMID:25730969   PMID:25813826   PMID:33040447  


Genomics

Comparative Map Data
Calb2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81955,023,849 - 55,050,858 (-)NCBIGRCr8
mRatBN7.21938,114,435 - 38,141,438 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1938,114,424 - 38,141,438 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1944,920,886 - 44,947,919 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01945,574,230 - 45,601,269 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01947,883,801 - 47,910,840 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01941,482,743 - 41,509,617 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1941,482,728 - 41,509,658 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01952,310,641 - 52,337,700 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41940,023,072 - 40,051,150 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11940,027,952 - 40,056,031 (-)NCBI
Celera1937,512,226 - 37,538,062 (-)NCBICelera
Cytogenetic Map19q12NCBI
CALB2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381671,358,723 - 71,390,433 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1671,358,713 - 71,390,436 (+)EnsemblGRCh38hg38GRCh38
GRCh371671,392,626 - 71,424,336 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361669,950,127 - 69,981,842 (+)NCBINCBI36Build 36hg18NCBI36
Build 341669,950,126 - 69,981,836NCBI
Celera1655,708,128 - 55,740,202 (+)NCBICelera
Cytogenetic Map16q22.2NCBI
HuRef1657,186,719 - 57,192,385 (+)NCBIHuRef
HuRef1657,160,840 - 57,186,546 (+)NCBIHuRef
CHM1_11672,805,453 - 72,837,193 (+)NCBICHM1_1
T2T-CHM13v2.01677,174,637 - 77,207,658 (+)NCBIT2T-CHM13v2.0
Calb2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398110,869,158 - 110,894,844 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8110,864,134 - 110,894,842 (-)EnsemblGRCm39 Ensembl
GRCm388110,142,526 - 110,168,212 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8110,137,502 - 110,168,210 (-)EnsemblGRCm38mm10GRCm38
MGSCv378112,666,438 - 112,692,106 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368113,031,667 - 113,057,335 (-)NCBIMGSCv36mm8
Celera8114,365,078 - 114,391,219 (-)NCBICelera
Cytogenetic Map8D3NCBI
cM Map857.44NCBI
Calb2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554844,075,067 - 4,103,559 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554844,075,103 - 4,103,509 (+)NCBIChiLan1.0ChiLan1.0
CALB2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21882,768,831 - 82,801,912 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11688,702,425 - 88,982,493 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01653,620,317 - 53,653,372 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11671,195,770 - 71,227,937 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1671,195,770 - 71,227,937 (+)Ensemblpanpan1.1panPan2
CALB2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1577,178,158 - 77,205,663 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl577,177,951 - 77,205,671 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha577,139,985 - 77,167,208 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0577,616,925 - 77,644,159 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl577,616,951 - 77,644,096 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1577,437,354 - 77,464,585 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0577,260,506 - 77,287,715 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0577,759,356 - 77,786,581 (+)NCBIUU_Cfam_GSD_1.0
Calb2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934937,217,095 - 37,244,688 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647522,341,822 - 22,372,609 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647522,344,416 - 22,372,015 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CALB2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl614,391,857 - 14,420,663 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1614,392,220 - 14,420,663 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2613,904,114 - 13,933,267 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CALB2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1554,503,635 - 54,538,304 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl554,504,082 - 54,538,441 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604717,312,991 - 17,345,343 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Calb2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474613,548,540 - 13,578,501 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474613,549,339 - 13,577,929 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Calb2
103 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:88
Count of miRNA genes:73
Interacting mature miRNAs:83
Transcripts:ENSRNOT00000022943
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9589102Slep13Serum leptin concentration QTL 134.630.001blood leptin amount (VT:0005667)plasma leptin level (CMO:0000781)1956937445569374Rat
8694186Bw152Body weight QTL 1523.340.001body mass (VT:0001259)body weight gain (CMO:0000420)1956937445569374Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19218792746708701Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19218792756457239Rat
61447Tcas1Tongue tumor susceptibility QTL 16.08tongue integrity trait (VT:0010553)squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)19231612147316121Rat
2317848Alcrsp21Alcohol response QTL 211.8999999761581420.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)19320477748204777Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19409615555283277Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19745724942983518Rat
724565Tcas5Tongue tumor susceptibility QTL 510.04tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)19997775339654489Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191082797043544039Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)191545586057337602Rat
1331788Rf45Renal function QTL 452.818kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)191560502346559041Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)191563020157337602Rat
2298478Eau8Experimental allergic uveoretinitis QTL 80.0163uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)191715443357337602Rat
61350Bp32Blood pressure QTL 320.012arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)192048357557337602Rat
1549835Tcas7Tongue tumor susceptibility QTL 70.001tongue integrity trait (VT:0010553)squamous cell carcinoma of the head and neck tumor number (CMO:0001876)192481797839654489Rat
724546Kidm3Kidney mass QTL 33.1kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)192932249057337602Rat
1358200Insglur2Insulin/glucose ratio QTL 24.1blood glucose amount (VT:0000188)serum insulin level (CMO:0000358)193383821455283146Rat
1358200Insglur2Insulin/glucose ratio QTL 24.1blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)193383821455283146Rat

Markers in Region
D19Rat71  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21938,130,095 - 38,130,307 (-)MAPPERmRatBN7.2
Rnor_6.01941,493,877 - 41,494,088NCBIRnor6.0
Rnor_5.01952,321,960 - 52,322,171UniSTSRnor5.0
RH 3.4 Map19437.4RGD
RH 3.4 Map19437.4UniSTS
RH 2.0 Map19481.8RGD
SHRSP x BN Map1927.8698RGD
Cytogenetic Map19q12UniSTS
X73985  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21938,114,703 - 38,114,871 (-)MAPPERmRatBN7.2
Rnor_6.01941,509,181 - 41,509,348NCBIRnor6.0
Rnor_5.01952,337,264 - 52,337,431UniSTSRnor5.0
RGSC_v3.41940,023,341 - 40,023,508UniSTSRGSC3.4
Celera1937,512,495 - 37,512,662UniSTS
Cytogenetic Map19q12UniSTS
RH138609  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21938,114,524 - 38,114,704 (-)MAPPERmRatBN7.2
Rnor_6.01941,509,348 - 41,509,527NCBIRnor6.0
Rnor_5.01952,337,431 - 52,337,610UniSTSRnor5.0
RGSC_v3.41940,023,162 - 40,023,341UniSTSRGSC3.4
Celera1937,512,316 - 37,512,495UniSTS
RH 3.4 Map19437.3UniSTS
Cytogenetic Map19q12UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 72 19
Low 1 9 1 13 1 2 2 2 16 18 3 2
Below cutoff 26 25 21 6 21 6 6 12 4 3 6

Sequence


RefSeq Acc Id: ENSRNOT00000022943   ⟹   ENSRNOP00000022943
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1938,114,435 - 38,141,438 (-)Ensembl
Rnor_6.0 Ensembl1941,482,728 - 41,509,658 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000096342   ⟹   ENSRNOP00000090456
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1938,114,424 - 38,138,156 (-)Ensembl
RefSeq Acc Id: NM_053988   ⟹   NP_446440
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81955,023,849 - 55,050,858 (-)NCBI
mRatBN7.21938,114,435 - 38,141,438 (-)NCBI
Rnor_6.01941,482,743 - 41,509,617 (+)NCBI
Rnor_5.01952,310,641 - 52,337,700 (+)NCBI
RGSC_v3.41940,023,072 - 40,051,150 (-)RGD
Celera1937,512,226 - 37,538,062 (-)RGD
Sequence:
RefSeq Acc Id: NP_446440   ⟸   NM_053988
- UniProtKB: P47728 (UniProtKB/Swiss-Prot),   A6IZ54 (UniProtKB/TrEMBL),   A0A8I6ADK6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000022943   ⟸   ENSRNOT00000022943
RefSeq Acc Id: ENSRNOP00000090456   ⟸   ENSRNOT00000096342
Protein Domains
EF-hand

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P47728-F1-model_v2 AlphaFold P47728 1-271 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701129
Promoter ID:EPDNEW_R11653
Type:single initiation site
Name:Calb2_1
Description:calbindin 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01941,482,726 - 41,482,786EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620981 AgrOrtholog
BioCyc Gene G2FUF-5694 BioCyc
Ensembl Genes ENSRNOG00000016977 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055019421 UniProtKB/Swiss-Prot
  ENSRNOG00060012743 UniProtKB/Swiss-Prot
  ENSRNOG00065011171 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000022943 ENTREZGENE
  ENSRNOT00000022943.5 UniProtKB/Swiss-Prot
  ENSRNOT00000096342.1 UniProtKB/TrEMBL
  ENSRNOT00055033152 UniProtKB/Swiss-Prot
  ENSRNOT00060021650 UniProtKB/Swiss-Prot
  ENSRNOT00065018085 UniProtKB/Swiss-Prot
Gene3D-CATH EF-hand UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7312595 IMAGE-MGC_LOAD
InterPro CALB2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF-hand-dom_pair UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF_Hand_1_Ca_BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF_hand_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:117059 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:105356 IMAGE-MGC_LOAD
NCBI Gene 117059 ENTREZGENE
PANTHER CALBINDIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR19972:SF4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam EF-hand_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF-hand_5 UniProtKB/TrEMBL
  EF-hand_7 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Calb2 PhenoGen
PROSITE EF_HAND_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF_HAND_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000016977 RatGTEx
  ENSRNOG00055019421 RatGTEx
  ENSRNOG00060012743 RatGTEx
  ENSRNOG00065011171 RatGTEx
SMART EFh UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47473 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6ADK6 ENTREZGENE, UniProtKB/TrEMBL
  A6IZ53_RAT UniProtKB/TrEMBL
  A6IZ54 ENTREZGENE, UniProtKB/TrEMBL
  A6IZ55_RAT UniProtKB/TrEMBL
  CALB2_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-08-06 Calb2  calbindin 2      Symbol and Name status set to provisional 70820 PROVISIONAL