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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Samd8 | Rat | (1->4)-beta-D-glucan | multiple interactions | ISO | Samd8 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of SAMD8 mRNA | CTD | PMID:36331819 | Samd8 | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Samd8 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of SAMD8 mRNA | CTD | PMID:22206623 | Samd8 | Rat | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of SAMD8 mRNA | CTD | PMID:29097150 | Samd8 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of SAMD8 mRNA | CTD | PMID:21215274 | Samd8 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Samd8 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of SAMD8 mRNA | CTD | PMID:28213091 | Samd8 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Samd8 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to SAMD8 gene] | CTD | PMID:28213091 | Samd8 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Samd8 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of SAMD8 mRNA | CTD | PMID:19465110 and PMID:24680724 | Samd8 | Rat | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 4-dinitrotoluene affects the expression of SAMD8 mRNA | CTD | PMID:21346803 | Samd8 | Rat | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 6-dinitrotoluene affects the expression of SAMD8 mRNA | CTD | PMID:21346803 | Samd8 | Rat | acetamide | decreases expression | EXP | | 6480464 | acetamide results in decreased expression of SAMD8 mRNA | CTD | PMID:31881176 | Samd8 | Rat | acrylamide | increases expression | EXP | | 6480464 | Acrylamide results in increased expression of SAMD8 mRNA | CTD | PMID:28959563 | Samd8 | Rat | aflatoxin B1 | increases expression | ISO | Samd8 (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of SAMD8 mRNA | CTD | PMID:19770486 | Samd8 | Rat | aflatoxin B1 | increases expression | ISO | SAMD8 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased expression of SAMD8 mRNA | CTD | PMID:21641981 | Samd8 | Rat | all-trans-retinoic acid | increases expression | ISO | SAMD8 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of SAMD8 mRNA | CTD | PMID:33167477 | Samd8 | Rat | arsenous acid | increases expression | ISO | SAMD8 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of SAMD8 mRNA | CTD | PMID:20458559 | Samd8 | Rat | benzo[a]pyrene | increases expression | ISO | SAMD8 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of SAMD8 mRNA | CTD | PMID:20064835 | Samd8 | Rat | benzo[a]pyrene | decreases methylation | ISO | SAMD8 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of SAMD8 3' UTR | CTD | PMID:27901495 | Samd8 | Rat | benzo[a]pyrene | increases methylation | ISO | SAMD8 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of SAMD8 promoter | CTD | PMID:27901495 | Samd8 | Rat | benzo[a]pyrene | decreases expression | ISO | Samd8 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of SAMD8 mRNA | CTD | PMID:22228805 | Samd8 | Rat | benzo[e]pyrene | increases methylation | ISO | SAMD8 (Homo sapiens) | 6480464 | benzo(e)pyrene results in increased methylation of SAMD8 intron | CTD | PMID:30157460 | Samd8 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of SAMD8 mRNA | CTD | PMID:25181051 more ... | Samd8 | Rat | cadmium atom | multiple interactions | ISO | SAMD8 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of SAMD8 mRNA | CTD | PMID:35301059 | Samd8 | Rat | cadmium dichloride | increases expression | ISO | SAMD8 (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of SAMD8 mRNA | CTD | PMID:38568856 | Samd8 | Rat | cadmium dichloride | multiple interactions | ISO | SAMD8 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of SAMD8 mRNA | CTD | PMID:35301059 | Samd8 | Rat | chlormequat chloride | increases expression | EXP | | 6480464 | Chlormequat results in increased expression of SAMD8 protein | CTD | PMID:34958886 | Samd8 | Rat | chloroprene | increases expression | EXP | | 6480464 | Chloroprene results in increased expression of SAMD8 mRNA | CTD | PMID:23125180 | Samd8 | Rat | choline | multiple interactions | ISO | Samd8 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of SAMD8 gene | CTD | PMID:20938992 | Samd8 | Rat | cobalt dichloride | increases expression | ISO | Samd8 (Mus musculus) | 6480464 | cobaltous chloride results in increased expression of SAMD8 mRNA | CTD | PMID:21139344 | Samd8 | Rat | cobalt dichloride | increases expression | ISO | SAMD8 (Homo sapiens) | 6480464 | cobaltous chloride results in increased expression of SAMD8 mRNA | CTD | PMID:19320972 | Samd8 | Rat | cobalt dichloride | increases expression | EXP | | 6480464 | cobaltous chloride results in increased expression of SAMD8 mRNA | CTD | PMID:24386269 | Samd8 | Rat | copper(II) sulfate | increases expression | ISO | SAMD8 (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of SAMD8 mRNA | CTD | PMID:19549813 | Samd8 | Rat | cyclosporin A | increases expression | ISO | SAMD8 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of SAMD8 mRNA | CTD | PMID:25562108 | Samd8 | Rat | cyclosporin A | decreases methylation | ISO | SAMD8 (Homo sapiens) | 6480464 | Cyclosporine results in decreased methylation of SAMD8 promoter | CTD | PMID:27989131 | Samd8 | Rat | DDE | decreases expression | ISO | SAMD8 (Homo sapiens) | 6480464 | Dichlorodiphenyl Dichloroethylene results in decreased expression of SAMD8 mRNA | CTD | PMID:38568856 | Samd8 | Rat | diarsenic trioxide | increases expression | ISO | SAMD8 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of SAMD8 mRNA | CTD | PMID:20458559 | Samd8 | Rat | Dibutyl phosphate | affects expression | ISO | SAMD8 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of SAMD8 mRNA | CTD | PMID:37042841 | Samd8 | Rat | dimethylarsinous acid | increases expression | ISO | SAMD8 (Homo sapiens) | 6480464 | dimethylarsinous acid results in increased expression of SAMD8 mRNA | CTD | PMID:23487506 | Samd8 | Rat | doxorubicin | decreases expression | ISO | SAMD8 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of SAMD8 mRNA | CTD | PMID:29803840 | Samd8 | Rat | folic acid | multiple interactions | ISO | Samd8 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of SAMD8 gene | CTD | PMID:20938992 | Samd8 | Rat | ketoconazole | increases expression | ISO | SAMD8 (Homo sapiens) | 6480464 | Ketoconazole results in increased expression of SAMD8 mRNA | CTD | PMID:36621641 | Samd8 | Rat | L-methionine | multiple interactions | ISO | Samd8 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of SAMD8 gene | CTD | PMID:20938992 | Samd8 | Rat | lead(0) | affects expression | ISO | SAMD8 (Homo sapiens) | 6480464 | Lead affects the expression of SAMD8 mRNA | CTD | PMID:28903495 | Samd8 | Rat | leflunomide | increases expression | ISO | SAMD8 (Homo sapiens) | 6480464 | leflunomide results in increased expression of SAMD8 mRNA | CTD | PMID:28988120 | Samd8 | Rat | methapyrilene | increases methylation | ISO | SAMD8 (Homo sapiens) | 6480464 | Methapyrilene results in increased methylation of SAMD8 intron | CTD | PMID:30157460 | Samd8 | Rat | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of SAMD8 gene | CTD | PMID:35440735 | Samd8 | Rat | methylmercury chloride | increases expression | ISO | SAMD8 (Homo sapiens) | 6480464 | methylmercuric chloride results in increased expression of SAMD8 mRNA | CTD | PMID:28001369 | Samd8 | Rat | nickel atom | increases expression | ISO | SAMD8 (Homo sapiens) | 6480464 | Nickel results in increased expression of SAMD8 mRNA | CTD | PMID:23195993 | Samd8 | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of SAMD8 mRNA | CTD | PMID:33387578 | Samd8 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Samd8 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of SAMD8 mRNA | CTD | PMID:36331819 | Samd8 | Rat | rotenone | increases expression | EXP | | 6480464 | Rotenone results in increased expression of SAMD8 mRNA | CTD | PMID:19013527 | Samd8 | Rat | sodium arsenate | increases expression | ISO | Samd8 (Mus musculus) | 6480464 | sodium arsenate results in increased expression of SAMD8 mRNA | CTD | PMID:21795629 | Samd8 | Rat | sodium arsenite | increases expression | ISO | SAMD8 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of SAMD8 mRNA | CTD | PMID:38568856 | Samd8 | Rat | tetrachloroethene | increases expression | ISO | Samd8 (Mus musculus) | 6480464 | Tetrachloroethylene results in increased expression of SAMD8 mRNA | CTD | PMID:28973375 | Samd8 | Rat | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of SAMD8 mRNA | CTD | PMID:31150632 | Samd8 | Rat | thiram | increases expression | ISO | SAMD8 (Homo sapiens) | 6480464 | Thiram results in increased expression of SAMD8 mRNA | CTD | PMID:38568856 | Samd8 | Rat | titanium dioxide | decreases methylation | ISO | Samd8 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of SAMD8 gene | CTD | PMID:35295148 | Samd8 | Rat | torcetrapib | increases expression | ISO | SAMD8 (Homo sapiens) | 6480464 | torcetrapib results in increased expression of SAMD8 mRNA | CTD | PMID:23228038 | Samd8 | Rat | triphenyl phosphate | affects expression | ISO | SAMD8 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of SAMD8 mRNA | CTD | PMID:37042841 | Samd8 | Rat | troglitazone | decreases expression | ISO | Samd8 (Mus musculus) | 6480464 | troglitazone results in decreased expression of SAMD8 mRNA | CTD | PMID:28973697 | Samd8 | Rat | urethane | increases expression | ISO | SAMD8 (Homo sapiens) | 6480464 | Urethane results in increased expression of SAMD8 mRNA | CTD | PMID:28818685 | Samd8 | Rat | valproic acid | increases methylation | ISO | SAMD8 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of SAMD8 gene | CTD | PMID:29154799 | Samd8 | Rat | valproic acid | increases expression | ISO | SAMD8 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of SAMD8 mRNA | CTD | PMID:23179753 and PMID:29154799 | Samd8 | Rat | vinclozolin | affects expression | EXP | | 6480464 | vinclozolin affects the expression of SAMD8 mRNA | CTD | PMID:19015723 | Samd8 | Rat | vinclozolin | increases methylation | EXP | | 6480464 | vinclozolin results in increased methylation of SAMD8 gene | CTD | PMID:31682807 | Samd8 | Rat | zinc atom | multiple interactions | ISO | SAMD8 (Homo sapiens) | 6480464 | [PCI 5002 co-treated with Zinc] results in increased expression of SAMD8 mRNA | CTD | PMID:18593933 | Samd8 | Rat | zinc(0) | multiple interactions | ISO | SAMD8 (Homo sapiens) | 6480464 | [PCI 5002 co-treated with Zinc] results in increased expression of SAMD8 mRNA | CTD | PMID:18593933 | |